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Journal of Pediatric Urology

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https://www.readbyqxmd.com/read/28713004/results-of-a-prospective-randomized-control-trial-comparing-hydrophilic-to-uncoated-catheters-in-children-with-neurogenic-bladder
#1
William DeFoor, Pramod Reddy, Melissa Reed, Brian VanderBrink, Elizabeth Jackson, Bin Zhang, Julie Denlinger, Paul Noh, Eugene Minevich, Curtis Sheldon
INTRODUCTION: Children with neurogenic bladder (NGB) often require a lifetime of clean intermittent catheterization (CIC), typically using uncoated catheters (UCs). Hydrophilic catheters (HCs) have lower friction than UCs with reported less damage to the urethra. The purpose of this study is to compare outcomes between these catheters. METHODS: An investigator-initiated, prospective, randomized clinical trial was conducted to compare HCs versus UCs. Children aged 2-17 years with NGB on CIC were enrolled for 1 year...
July 4, 2017: Journal of Pediatric Urology
https://www.readbyqxmd.com/read/28716390/impact-of-cytokine-genetic-polymorphisms-on-the-risk-of-renal-parenchymal-infection-in-children
#2
Almontaser Hussein, Eman Askar, Ahlam Badawy, Khaled Saad, Asmaa Zahran, Ahmad A Elderwy
BACKGROUND: Acute pyelonephritis is associated with renal scarring in up to 30% of patients. Renal scarring may cause significant long-term morbidity. The pathogenesis of acute pyelonephritis remains unclear, although it involves interaction among uroepithelium, the immune system cells, and the locally produced cytokines. That some UTI-prone children develop acute pyelonephritis, and eventually renal parenchymal scarring, suggests a genetic role. Interleukin-6, interleukin-8, chemokine receptor-1 (CXCR1), and tumor necrosis factor-alpha (TNFα), the key regulators of the host immune responses, are proteins whose secretion is controlled by genes...
July 3, 2017: Journal of Pediatric Urology
https://www.readbyqxmd.com/read/28713007/future-fertility-for-individuals-with-differences-of-sex-development-parent-attitudes-and-perspectives-about-decision-making
#3
Emilie K Johnson, Ilina Rosoklija, Angela Shurba, Anthony D'Oro, Elisa J Gordon, Diane Chen, Courtney Finlayson, Jane L Holl
BACKGROUND: Children, adolescents, and young adults (children/youth) with differences/disorders of sex development (DSD) face challenges related to future fertility; this may be due to variations in gonadal development, and, for some, gonadectomy performed to reduce the risk of malignancy. Childhood may be the only time for preservation of biological fertility potential for children/youth who undergo gonadectomy or have early gonadal failure. Fertility-related decision-making for these patients is particularly complicated, due to the need for parental proxy decision-making, potential discordance between gender identity and gonadal type, and uncertain future assisted reproductive technologies...
July 3, 2017: Journal of Pediatric Urology
https://www.readbyqxmd.com/read/28713005/steroid-5-alpha-reductase-type-2-srd5a2-gene-v89l-polymorphism-and-hypospadias-risk-a-meta-analysis
#4
K Zhang, Y Li, Y Mao, M Ma
BACKGROUND: Hypospadias is a common congenital malformation in males, in which the urethral orifice is found on the ventral side of the penis as a result of incomplete fusion of urethral folds. The etiology of hypospadias is poorly understood, and may be multifactorial, including genetic, endocrine and environmental factors. The steroid 5-alpha-reductase type 2 (SRD5A2) gene, which is mainly expressed in the ventral side of the urethra in the process of male genital development, plays an important role in urethral shaping...
June 28, 2017: Journal of Pediatric Urology
https://www.readbyqxmd.com/read/28689649/epispadias-repair-with-tunica-vaginalis-flap
#5
R S Zee, J H Makari, Fernando Ferrer, C D A Herndon
INTRODUCTION: Primary epispadias is a rare congenital malformation that afflicts about 1 in 80,000 children. The surgical repair, originally described by Cantwell over 100 years ago, is fundamentally sound and incorporates several important steps to achieve an optimal result. METHODS: A 9-month-old male with penopubic epispadias presented for surgical repair. Pre-operative imaging included a normal renal ultrasound and voiding cystourethrogram that demonstrated a moderate-sized bladder, partially competent bladder neck, and no vesicoureteral reflux...
June 27, 2017: Journal of Pediatric Urology
https://www.readbyqxmd.com/read/28689648/clinical-and-genetic-characterization-of-chinese-pediatric-cystine-stone-patients
#6
Luming Shen, Xiaoming Cong, Xin Zhang, Ninghong Wang, Ping Zhou, Yan Xu, Qingyi Zhu, Xiaojian Gu
INTRODUCTION: Cystine stone is the only clinical manifestation in patients with cystinuria, which is an autosomal recessive inheritable disease. However, clinical and genetic data vary among patients in different countries. OBJECTIVE: To investigate the characteristics of Chinese pediatric cystine stone patients. PATIENTS AND METHODS: Thirteen pediatric patients with cystine stones were evaluated in our clinic between 2012 and 2015. Gene mutations in SLC3A1 and SLC7A9 were investigated...
June 24, 2017: Journal of Pediatric Urology
https://www.readbyqxmd.com/read/28688994/comparison-of-30-day-emergency-department-bouncebacks-after-pediatric-versus-adult-urologic-surgery
#7
Courtney L Shepard, Julian Wan
INTRODUCTION: More pediatric patients seem to present to the emergency department (ED) for non-urgent matters after urologic procedures than adult patients. Under new and expanding healthcare reform, pediatric urologists may be penalized for these visits. We compare our 30-day postoperative bounceback rates to the ED and the acuity of the concerns in these populations. MATERIALS AND METHODS: All urology consults at our institution are maintained on a prospectively tracked database...
June 20, 2017: Journal of Pediatric Urology
https://www.readbyqxmd.com/read/28673795/use-of-3d-reconstruction-cloacagrams-and-3d-printing-in-cloacal-malformations
#8
Jennifer J Ahn, Margarett Shnorhavorian, Anne-Marie E Amies Oelschlager, Beth Ripley, Giridhar M Shivaram, Jeffrey R Avansino, Paul A Merguerian
INTRODUCTION: Cloacal anomalies are complex to manage, and the anatomy affects prognosis and management. Assessment historically includes examination under anesthesia, and genitography is often performed, but these do not consistently capture three-dimensional (3D) detail or spatial relationships of the anatomic structures. Three-dimensional reconstruction cloacagrams can provide a high level of detail including channel measurements and the level of the cloaca (<3 cm vs. >3 cm), which typically determines the approach for surgical reconstruction and can impact long-term prognosis...
June 20, 2017: Journal of Pediatric Urology
https://www.readbyqxmd.com/read/28713006/ultrasonographic-findings-in-the-epididymis-of-pediatric-patients-with-testicular-torsion
#9
C E Afsarlar, R Elizondo, E Yilmaz, E Cakmakci, D J Ballow, E Demir, G Guney, C J Koh
INTRODUCTION: Although grayscale ultrasound and color Doppler ultrasound characteristics of the torsed testis are well established in the literature, less is known about its anatomic partner: the epididymis. OBJECTIVE: The purpose of this study was to describe the ultrasound characteristics of the epididymis in pediatric patients with testicular torsion, and to describe their potential role as prognostic criteria for testicular salvage outcomes. STUDY DESIGN: During a retrospective review of 217 pediatric patients with acute testicular torsion during 2009-2016, morphological features of the epididymis from scrotal ultrasounds (size, parenchymal characteristics, and vascular flow of both epididymis heads), as well as patient demographics, time duration, surgical outcomes, histopathology results, and follow-up periods were analyzed...
June 19, 2017: Journal of Pediatric Urology
https://www.readbyqxmd.com/read/28713003/reassessing-the-utility-of-routine-urine-culture-with-urodynamics-uti-incidence-and-risk-factors
#10
Devon C Snow-Lisy, Christopher Halline, Emilie K Johnson, Dawn Diaz-Saldano, Theresa Meyer, Elizabeth B Yerkes
INTRODUCTION: There is no consensus regarding use of periprocedural antibiotics or routine urine cultures during urodynamics study (UDS) in children. At our hospital, we historically have obtained urine cultures during UDS. However, even with positive cultures, few patients require treatment. Most are successfully managed with increased hydration and frequent bladder emptying. PURPOSE: To evaluate clinical characteristics, antibiotic treatment, and outcomes in patients undergoing UDS to identify (1) risk factors for urinary tract infection (UTI) after UDS, and (2) patients who may benefit from routine urine culture...
June 19, 2017: Journal of Pediatric Urology
https://www.readbyqxmd.com/read/28679474/a-comparison-of-micro-perc-and-retrograde-intrarenal-surgery-results-in-pediatric-patients-with-renal-stones
#11
Haluk Sen, Ilker Seckiner, Omer Bayrak, Kazim Dogan, Sakip Erturhan
INTRODUCTION: With advancements in endoscopic surgery, open surgical techniques for urinary system stones have paved the way for the application of less invasive treatment modalities in patients with pediatric kidney stone disease. These treatment options include extracorporeal shock wave lithotripsy (ESWL), percutaneous nephrolithotomy (PCNL), and retrograde intrarenal surgery (RIRS). OBJECTIVE: We aimed to compare the efficacy and safety of RIRS and micro-PCNL techniques in the surgical treatment of kidney stones in pediatric patients...
June 19, 2017: Journal of Pediatric Urology
https://www.readbyqxmd.com/read/28676152/early-vs-late-presenting-urethroplasty-complications-after-hypospadias-repair-a-retrospective-analysis-of-patient-follow-up
#12
Mark A Faasse, Dennis B Liu
INTRODUCTION: Complications after primary hypospadias repair often present late, that is, more than 1 year postoperatively. This has important implications for clinical practice and prospective research protocols. Follow-up regimen-or lack thereof-may contribute to delayed diagnosis of complications. OBJECTIVE: To characterize and compare the follow-up regimens of patients with early and late-presenting urethroplasty complications after primary hypospadias repair, specifically noting the length of time between encounters during which complications emerged...
June 19, 2017: Journal of Pediatric Urology
https://www.readbyqxmd.com/read/28669585/commentary-to-attitudes-towards-disorders-of-sex-development-nomenclature-among-affected
#13
Pierre Mouriquand
No abstract text is available yet for this article.
June 19, 2017: Journal of Pediatric Urology
https://www.readbyqxmd.com/read/28669584/re-fertility-in-disorders-of-sex-development-a-review
#14
LETTER
Nicolás Fernández
No abstract text is available yet for this article.
June 19, 2017: Journal of Pediatric Urology
https://www.readbyqxmd.com/read/28688993/fat-demented-and-stupid-an-unrecognized-legacy-of-pediatric-urology
#15
REVIEW
Christopher S Cooper
The human body is an unfathomably intricate structure consisting of many connected and intertwined systems. This makes it impossible for therapeutic interventions to selectively target only one physiologic system without some impact or side effects on all the other systems. The resiliency of the human body modifies and disguises side effects, some of which may be undetectable for years and not apparent without scientific investigation. Pediatric urologists employ relatively few medications for the common conditions they treat and in general these consist of antibiotics, anticholinergics, and anesthetics...
June 17, 2017: Journal of Pediatric Urology
https://www.readbyqxmd.com/read/28666918/urinary-tract-infection-after-retrograde-urethrogram-in-children-a-multicenter-study
#16
Neha R Malhotra, Jared R Green, Cynthia K Rigsby, Jane L Holl, Earl Y Cheng, Emilie K Johnson
INTRODUCTION: The risk of post-procedural urinary tract infection (ppUTI) after retrograde urethrogram (RUG) has not been well quantified. Prophylactic antibiotics may reduce the risk, but must be weighed against the risks of antibiotic resistance. Prior research has shown that this risk is variable after voiding cystourethrogram (0-42% reported ppUTI rate) and appears to be low after urodynamics (0-4.8%) but this risk has not been well documented for patients undergoing RUG. OBJECTIVE: We aimed to (1) describe the rate of ppUTI after RUG, and (2) examine factors associated with use of antibiotics at the time of RUG...
June 17, 2017: Journal of Pediatric Urology
https://www.readbyqxmd.com/read/28711548/experience-with-specially-designed-pored-polyacetal-mold-dressing-method-used-in-mcindoe-style-vaginoplasty
#17
So-Eun Han, Ju Young Go, Doo Seok Choi, Gi Hong Seo, So Young Lim
INTRODUCTION: Appropriate postoperative care and prolonged use of the mold are prerequisites for achieving successful results in McIndoe-style vaginoplasty. OBJECTIVE: We introduce a specially designed pored polyacetal mold to maintain the reconstructed vagina, with favorable long-term results allowing drainage of the serous and bloody discharge without removal of the mold, and reduction of infection rate and the chance of skin graft shearing in McIndoe vaginoplasty...
June 16, 2017: Journal of Pediatric Urology
https://www.readbyqxmd.com/read/28687410/radiographic-gapometry-score-a-simple-predictor-for-surgical-approach-in-pediatric-traumatic-posterior-urethral-strictures
#18
Virender Sekhon, Sharmad J Kudchadkar, Anubhav Raj, M S Ansari
BACKGROUND: Post-traumatic posterior urethral injuries in children are rare events. Their management algorithms are extrapolations from adult literature and they continue to pose a difficult challenge for pediatric urologists. Not much data for age-related feasibility of an end-to-end urethroplasty are available. OBJECTIVE: This study was designed to validate a simple preoperative radiographic score to predict the type of surgical repair for traumatic posterior urethral strictures in children...
June 16, 2017: Journal of Pediatric Urology
https://www.readbyqxmd.com/read/28673796/sleep-disordered-breathing-in-enuretic-children-and-controls
#19
Ingrid Jönson Ring, Agneta Markström, Farhan Bazargani, Tryggve Nevéus
INTRODUCTION: Nocturnal enuresis and sleep disordered breathing are common childhood problems that are reported to be associated with each other. Sleep disordered breathing is often found in children with upper airway obstruction and, according to some studies, its presence is associated with an increased risk of nocturnal enuresis. Respiration during sleep in children with therapy-resistant enuresis, but no history of snoring or sleep apneas, has previously been investigated, and subclinical signs of disordered respiration were found in this group...
June 16, 2017: Journal of Pediatric Urology
https://www.readbyqxmd.com/read/28669586/long-term-outcomes-of-cutaneous-vesicostomy-in-patients-with-neuropathic-bladder-caused-by-spina-bifida
#20
M İrfan Dönmez, Alonso Carrasco, Amanda F Saltzman, Vijaya Vemulakonda, Duncan T Wilcox
OBJECTIVE: To evaluate the outcomes of patients who underwent cutaneous vesicostomy for management of neuropathic bladder secondary to spina bifida. We hypothesize that vesicostomy, in select patients, is beneficial to prevent upper urinary tract deterioration (UTD), reduce febrile urinary tract infections (UTIs), and preserve renal function. STUDY DESIGN: We performed a retrospective chart review on patients with spina bifida who underwent cutaneous vesicostomy at our institution between 2000 and 2016...
June 16, 2017: Journal of Pediatric Urology
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