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International Journal of Pediatric Otorhinolaryngology

Raymond P Shupak, Bruce B Horswell, Marcus D Shaffer, Milton J Plata
Nodular fasciitis is a benign lesion uncommonly found in the head and neck region. Although described previously in adults, there have been no reports of nodular fasciitis in a child's tongue. A 4 month old male infant was referred for evaluation of a rapidly growing tongue lesion. He underwent excisional biopsy of the lesion. Initial pathology suggested a spindle cell tumor. Subsequent outside facility molecular testing was obtained and Nodular Fasciitis was confirmed. Nodular fasciitis is a rare benign tumor that can be often mistaken for malignancy...
October 2018: International Journal of Pediatric Otorhinolaryngology
Juliana L Manganella, Derek J Stiles, Kosuke Kawai, Devon L Barrett, Laura B O'Brien, Margaret A Kenna
OBJECTIVES: To examine if the tablet-based Agilis Health Mobile Audiogram (Agilis Audiogram) is an effective and valid measure of hearing thresholds compared to a pure-tone audiogram in an adult and pediatric population. METHODS: Participants underwent an otologic exam, conventional audiometric evaluation and the self-administered Agilis Audiogram. We examined whether the difference of pure-tone average (PTA) between the two measurement techniques fell within the equivalence range of ±8 dB...
October 2018: International Journal of Pediatric Otorhinolaryngology
Song Gao, Yi Jiang, Guojian Wang, Yongyi Yuan, Shasha Huang, Xue Gao, Xiaohong Li, Dejun Zhang, Jian Wu, Xiaowen Ji, Tao Deng, Ligang Wang, Dongyang Kang, Pu Dai
OBJECTIVE: Hereditary nonsyndromic hearing loss is extremely heterogeneous and an X-linked form accounts for 1-5% of all cases. The aim of this study was to identify the pathogenic variants in a nonsyndromic X-linked dominant hearing loss family, and explain the reason of different hearing phenotype in hearing between the two sisters with the same variant. METHODS: Targeted gene capture and next-generation sequencing were used to study the genetic cause. What's more, methylation differences among the androgen receptor genes were used to investigate whether the different hearing levels of the two sisters is related to X-chromosome inactivation (Xi)...
October 2018: International Journal of Pediatric Otorhinolaryngology
Yue Wang, Wenshan Xing, Tun Liu, Xu Zhou, Jin Qian, Bingqing Wang, Shouqin Zhao, Qingguo Zhang
BACKGROUND: Congenital bilateral microtia with external ear canal (EAC)/middle ear malformation lead to severe appearance defects, hearing impairment and language barrier. Here we report an optimal integrated surgical technique for BoneBridge implantation and auricular reconstruction, which reduce time span of operation, total cost and patients' suffering as well. METHOD: Seven patients with bilateral external and middle ear malformation received 2-stage auricular reconstruction (age from 7 to 11 years old)...
October 2018: International Journal of Pediatric Otorhinolaryngology
Mohammad Majid Oryadi-Zanjani
INTRODUCTION: Production of Infant Scale Evaluation (PRISE) is a popular parent-report scale used to assess the pre-first word vocalization of children. There is not any tool to assess pre-verbal vocalizations in Persian speaking children. Therefore, considering the two important roles of pre-verbal vocalizations both in the early diagnosis of hearing impairment and in measuring the effectiveness of CIs and habilitation programs, we aimed to adapt and validate the PRISE questionnaire on Persian normal hearing children aged 3-18 months and estimate the PRISE's normative distribution for them...
October 2018: International Journal of Pediatric Otorhinolaryngology
Matthew R Hoffman, Katrina M Thompson, Jessica Van Beek-King
Idiopathic laryngotracheal stenosis is a fibroinflammatory stenosis in persons without alternative explanation such as trauma, intubation, or autoimmune disease. Patients are usually females of child-bearing age. We report on an 11-year-old male who developed progressive dyspnea and stridor. Bronchoscopy revealed 90% stenosis of the cervical trachea. He underwent serial balloon dilation with steroid injection; stenosis decreased to 20%. He had no history of intubation or trauma. Histologic and laboratory workup for autoimmune disease was negative...
October 2018: International Journal of Pediatric Otorhinolaryngology
Shruti Zaveri, Jeffrey C Rastatter, John M Carter, Stanley Kim, John Maddalozzo
INTRODUCTION: Successful pediatric revision thyroid surgery depends primarily on effective localization of recurrent or persistent lesions. Secondary to fibrosis and scarring, blind regional dissection can fail to retrieve the tissues of concern. Conventionally, high resolution CT or ultrasound of the neck has been used to map lesions within the thyroid bed. The success rate of excising recurrent lesions using these mapping techniques is at best 80%. We present a small series of patients in which hook wire localization was used to help localize and excise recurrent and/or persistent neck disease during secondary operations...
October 2018: International Journal of Pediatric Otorhinolaryngology
Han Jie Soh, Katherine Rowe, Margot J Davey, Rosemary S C Horne, Gillian M Nixon
OBJECTIVE: To develop and test a screening tool based on the OSA-18 questionnaire for triage of referrals for sleep-disordered breathing (SDB) in children. STUDY DESIGN: Consecutive children aged >2y without major comorbidities referred for polysomnography (PSG) or overnight oximetry for suspected obstructive sleep apnea (OSA) between 11 January and 31 May 2017 were included. OSA was defined by an obstructive apnea/hypopnea index (OAHI) >1event/h on PSG or an abnormal overnight oximetry (McGill Oximetry Score 2-4)...
October 2018: International Journal of Pediatric Otorhinolaryngology
Sofia Sousa, Magda Rocha, Francisco Patrão, Gabriel Pereira, Sofia Reis, Patrícia Horta, Conceição Salgado, Marques Dos Santos
INTRODUCTION: Drooling of saliva is the unintentional loss of saliva from the mouth resulting in excess pooling of saliva in the anterior portion of the oral cavity. It is considered normal in infants and usually resolves itself by 15-18 months of age. It is a common problem in pediatric patients with cerebral palsy or other neurological disorders. Drooling interferes with speech, impairs oral hygiene and contributes to oral dermatitis, aspiration pneumonias and fluid electrolyte imbalances...
October 2018: International Journal of Pediatric Otorhinolaryngology
James Johnston, Michael Hoggard, Kristi Biswas, Carmen Astudillo-García, Fiona J Radcliff, Murali Mahadevan, Richard G Douglas
INTRODUCTION: Culture-independent methods, based on bacterial 16 S rRNA gene sequencing, have been used previously to investigate the adenotonsillar microbiota. However, these studies have focused on a single sampling site (usually a surface swab). We aimed to investigate potential differences in adenotonsillar microbiota according to sampling location, both on and within the adenoids and palatine tonsils. METHODS: Pediatric patients (n = 28, mean age five years) undergoing adenotonsillectomy were recruited for this study...
October 2018: International Journal of Pediatric Otorhinolaryngology
Soukaina Elrharchi, Zied Riahi, Sara Salime, Halima Nahili, Hassan Rouba, Mostafa Kabine, Crystel Bonnet, Christine Petit, Abdelhamid Barakat
OBJECTIVES: Hearing loss (HL) is one of the most common sensorineural disorders. In the present study, we identified two novel missense mutations in BSND gene causing Bartter syndrome type IV which is a genetic disease with an autosomal recessive transmission, characterized by hypokalaemia, metabolic alkalosis, an elevation in plasma renin activity and hyperaldosteronism as well as sensorineural deafness. METHODS: Whole-exome sequencing was performed to study the genetic causes of Hearing loss in two unrelated patients from two Moroccan families...
October 2018: International Journal of Pediatric Otorhinolaryngology
F Jahshan, O Ertracht, A Abu Ammar, O Ronen, S Srouji, L Apel-Sarid, N Eisenbach, S Atar, E Sela, M Gruber
OBJECTIVE: Laryngotracheal damage is a well-described complication of endotracheal intubation and animal models are essential for studying the underlying cellular injury cascade. This novel rat model is based on transoral intubation and aims to simulate the common clinical scenario of tube-related airway damage. METHODS: Prospective randomized control pilot study. 28 male Sprague-Dawley were randomly assigned into three groups: control, 3-h' intubation and 6-h' intubation...
October 2018: International Journal of Pediatric Otorhinolaryngology
Mario A Mujica-Mota, Neel Patel, Issam Saliba
OBJECTIVE: Evidence shows type 1 diabetes(T1D) leads to vascular damage and neuropathy. The purpose of this study was to perform a systematic review and a meta-analysis to assess the evidence of the effects of T1D on hearing function. METHODS: Three electronic databases were used. The articles were independently reviewed by two authors using predefined inclusion criteria to identify eligible studies. They were then classified as high or low methodological quality...
October 2018: International Journal of Pediatric Otorhinolaryngology
Andrew A McCormick, Tony Tarchichi, Christopher Azbell, Lorelei Grunwaldt, Noel Jabbour
OBJECTIVE: A subglottic hemangioma (SGH) is a benign tumor of infancy that can cause severe obstruction of the airway. Infantile hemangiomas, in general, are the most common head and neck tumor in children, affecting 4-5% of the pediatric population. This retrospective cohort study characterizes subglottic infantile hemangiomas at a single vascular anomaly center over a 5-year period (2013-2017) during the era of propranolol treatment. METHODS: Queried the Vascular Anomaly Database at Children's Hospital of Pittsburgh for all infantile hemangioma(s) and then identified case of subglottic hemangiomas...
October 2018: International Journal of Pediatric Otorhinolaryngology
Miki Paker, Jacob T Cohen, Nedal Moed, Lev Shleizerman, Muhamed Masalha, Dror Ashkenazi, Salim Mazzawi
Septic thrombophlebitis of the facial vein (STFN) commonly presents with facial erythema, tenderness, and swelling above the involved vessel. Due to its rarity, diagnosis and treatment remain a challenge. Lemierre syndrome (LS), which consists of a triad of internal jugular vein thrombophlebitis, septicemia, and distant septic emboli, is a more common entity of which physicians are more familiar. Whether tonsillitis-related STFN is actually LS in a different anatomical area and shares the same characteristics is still left to be answered...
October 2018: International Journal of Pediatric Otorhinolaryngology
Valerie Cote, Marissa Schwartz, Jose F Arbouin Vargas, Michael Canfarotta, Katherine R Kavanagh, Usama Hamdan, Tulio A Valdez
INTRODUCTION: Cleft palate is one of the most common congenital anomalies, yet surgical repair remains challenging and can lead to significant complications in the hands of inexperienced surgeons. There is a great need for the development of a simulation model that will allow surgeons worldwide to learn and practice the intricate skills needed for cleft palate surgery. OBJECTIVES: 1. To develop a low-cost incomplete cleft palate simulation model using additive manufacturing technology (3D printing)...
October 2018: International Journal of Pediatric Otorhinolaryngology
Peter J Ciolek, Elise Kang, Julie A Honaker, Erika A Woodson, Brandon S Hopkins, Samantha Anne
INTRODUCTION: Objective of the study is to define rates of successful completion of components of pediatric vestibular testing (VT). METHODS: Retrospective review of VT performed on patients less than 18 years of age from 2004 to 2015. RESULTS: 188 pediatric patients (mean age: 13.9 ± 3.56 years old, range 2-17 years) underwent testing. Thirty-five (18.6%) had abnormal test results. Pediatric patients unable to complete all aspects of VT could still complete an average of 7...
October 2018: International Journal of Pediatric Otorhinolaryngology
Edward D Ferenczy, Michael J Stoner, Sandra P Spencer, Samantha W Gee, Daniel J Scherzer, Joseph D Tobias
OBJECTIVE: The objective of this study was to evaluate endotracheal tube cuff pressure after emergency intubation and identify variables associated with an elevated cuff pressure. METHODS: This was a prospective cohort study of intubated patients in the emergency department of Nationwide Children's Hospital. The primary study outcome, cuff pressure, was measured via manometer. Clinical details related to the intubation were collected and analyzed as secondary outcomes...
October 2018: International Journal of Pediatric Otorhinolaryngology
James Johnston, Michael Hoggard, Kristi Biswas, Carmen Astudillo-García, Sharon Waldvogel-Thurlow, Fiona J Radcliff, Murali Mahadevan, Richard G Douglas
INTRODUCTION: Obstructive sleep apnea (OSA) is now a more common indication for tonsillectomy than recurrent tonsillitis (RT) [1,2]. Few studies have addressed possible differences in pathogenesis between these two conditions. Children with RT and OSA are often being treated in the community with multiple courses of antibiotics before surgery. Current understanding of the role of bacteria in disorders of the tonsils is mainly based on the culture of tonsil swabs. Swab cultures reflect only a very small fraction of the bacteria present on the mucosal surface and may not represent the bacterial communities within the tonsil crypts [3,4]...
October 2018: International Journal of Pediatric Otorhinolaryngology
Nathalie Goulème, Michel Debue, Karen Spruyt, Catherine Vanderveken, Romolo Daniele De Siati, José Ortega-Solis, Jennifer Petrossi, Sylvette Wiener-Vacher, Maria Pia Bucci, Eugen Ionescu, Hung Thai-Van, Naïma Deggouj
BACKGROUND: The aim of this multicenter study is to investigate the effect of chronological age and gender in postural control. METHODS: To approach an ecological model, we used a multicenter posturography assessment. We analyzed postural control with surface, mean velocity of center of pressure [CoP] and temporal analysis, with Postural Instability Index [PII] being a more sensitive parameter in postural evaluation. A large sample of 156 age- and gender-matched healthy children recruited in several pediatrics hospitals, participated...
October 2018: International Journal of Pediatric Otorhinolaryngology
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