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Journal of Clinical Periodontology

Karina A F S Miller, Luciana S Branco-de-Almeida, Sandra Wolf, Nicole Hovencamp, Tina Treloar, Peter Harrison, Ikramuddin Aukhil, Yan Gong, Luciana M Shaddox
AIM: To evaluate long-term clinical response to periodontal therapy and maintenance in localized aggressive periodontitis (LAP). MATERIALS AND METHODS: One hundred forty-one African-Americans diagnosed with LAP, aged 5-25 years, were enrolled. Patients underwent periodontal mechanical debridement plus one week of amoxicillin/metronidazole. Mechanical therapy was repeated as needed and clinical parameters were recorded at baseline, 3, 6, 12, 18, and 24 months, and 2 additional annual follow-up visits after treatment...
October 21, 2016: Journal of Clinical Periodontology
Luigi Nibali, Anna Di Iorio, Yu-Kang Tu, Alexandre R Vieira
BACKGROUND: This study aimed to produce the latest summary of the evidence for association of host genetic variants contributing to both periodontitis and caries. MATERIALS AND METHODS: Two systematic searches of the literature were conducted in Ovid Medline, Embase, LILACS and Cochrane Library for large candidate gene studies, systematic reviews and GWAS reporting data on host genetic variants and presence of periodontal disease and caries. RESULTS: A total of 124 studies were included in the review (59 for the periodontitis outcome and 68 for the caries outcome), from an initial search of 15,487 titles...
October 18, 2016: Journal of Clinical Periodontology
Pierpaolo Cortellini, Jacopo Buti, Giovanpaolo Pini Prato, Maurizio S Tonetti
AIM: compare the long-term outcomes and costs of 3 treatment modalities in intrabony defects. MATERIALS AND METHODS: 45 intrabony defects in 45 patients had been randomly allocated to receive: modified papilla preservation technique with titanium reinforced e-polytetrafluoroethylene (ePTFE) membranes (MPPT Tit, N=15); access flap with e-PTFE membranes (Flap-ePTFE, N=15); access flap alone (Flap, N=15). Supportive periodontal care (SPC) was provided monthly for 1 year, then every 3 months for 20 years...
October 13, 2016: Journal of Clinical Periodontology
Jian Jiao, Dong Shi, Zhan-Qiang Cao, Huan-Xin Meng, Rui-Fang Lu, Li Zhang, Yi Song, Jing-Ren Zhao
AIM: To evaluate the effectiveness of non-surgical periodontal treatment (NSPT) and its influential factors in a large Chinese population with chronic periodontitis. METHODS: Periodontal examination data of 10,789 patients with at least one periodontal re-evaluation record were extracted from a hospital-based electronic periodontal charting record system. Probing depth (PD) and bleeding index (BI) reductions after NSPT and their influential factors were analyzed by multilevel analysis...
October 11, 2016: Journal of Clinical Periodontology
Suellen da Silva Maciel, Magda Feres, Tiago Eduardo Dias Gonçalves, Glaucia Santos Zimmermann, Hélio Doyle Pereira da Silva, Luciene Cristina Figueiredo, Poliana Mendes Duarte
AIM: To evaluate whether obesity affects the subgingival microbial composition of patients with periodontal health or chronic periodontitis (CP). MATERIALS AND METHODS: Based on periodontal parameters, body mass index and waist-hip ratio, 166 patients were allocated into one of the following groups: Normal weight (NW) patients with periodontal health (n=44), NW patients with CP (n=40), Obese patients with periodontal health (n=40) and obese patients with CP (n=42)...
October 7, 2016: Journal of Clinical Periodontology
Daniel S Thoma, Nadja Naenni, Goran I Benic, Christoph H F Hämmerle, Ronald E Jung
AIM: To test whether or not soft tissue augmentation with a collagen matrix (VCMX) leads to a similar increase in ridge width around dental implants compared to the use of an autogenous subepithelial connective tissue graft (SCTG). MATERIALS AND METHODS: In 12 dogs, immediate dental implants were placed with simultaneous guided bone regeneration. Three months later, soft tissue volume augmentation was performed by randomly allocating three treatment modalities to these sites (VCMX, SCTG, sham-operated group (control))...
October 7, 2016: Journal of Clinical Periodontology
Andressa Vilas Boas Nogueira, Rafael Scaf de Molon, Marjan Nokhbehsaim, James Deschner, Joni Augusto Cirelli
AIM: The present study aimed to evaluate the contribution of biomechanical loading to inflammation-induced tissue destruction. MATERIALS AND METHODS: A total of 144 adult Holtzman rats were randomly assigned into four experimental groups: control (C), ligature-induced periodontal disease (P), orthodontic movement (OM), and combination group (OMP). 1, 3, 7, and 15 days following baseline, 9 animals from each experimental group were sacrificed. Bone volume fraction (BVF) and bone mineral density (BMD) were measured using micro-computed tomography...
October 7, 2016: Journal of Clinical Periodontology
Oreste Iocca, Alessio Farcomeni, Simon Pardiñas-Lopez, Huzefa S Talib
AIMS: To conduct a traditional meta-analysis and a Bayesian Network meta-analysis to synthesize the information coming from Randomized Controlled Trials on different socket grafting materials and combine the resulting indirect evidence in order to make inferences on treatments that have not been compared directly. MATERIALS AND METHODS: RCTs were identified for inclusion in the systematic review and subsequent statistical analysis. Bone height and width remodeling were selected as the chosen summary measures for comparison...
October 6, 2016: Journal of Clinical Periodontology
Leena Jauhiainen, Anna Liisa Suominen, Noora Kanerva, Satu Männistö, Matti Knuuttila, Pekka Ylöstalo
AIM: To examine whether a Nordic diet measured by the Baltic Sea Diet Score (BSDS) and the Recommended Finnish Diet Score (RFDS) is associated with periodontal condition. MATERIAL AND METHODS: The study population consisted of non-smoking, non-diabetic and non-rheumatoid individuals in the Health 2000 Survey in Finland. Analyses were made in two age groups (30-49 years (n=1210) and 50-79 years (n=977)) and subsequently in two oral hygiene groups (good oral hygiene and poor oral hygiene)...
October 5, 2016: Journal of Clinical Periodontology
Ahmed E Al-Subaie, Marco Laurenti, Mohamed-Nur Abdallah, Iskandar Tamimi, Farid Yaghoubi, Hazem Eimar, Nicholas Makhoul, Faleh Tamimi
: Propranolol, a non-selective β-blocker widely used to treat cardiovascular conditions, favors bone accrual. Accordingly, we hypothesized that propranolol could be useful for improving bone healing and osseointegration. This in-vivo study was designed to investigate the effect of propranolol on bone healing and osseointegration in rats' tibiae. METHODS: On 24 Sprague-Dawley rats, a unicortical defect was created in the right tibial metaphysis of each rat and a custom made titanium implant was placed in the left tibia...
October 5, 2016: Journal of Clinical Periodontology
Xiangyu Sun, Eduardo Bernabé, Xuenan Liu, Jennifer E Gallagher, Shuguo Zheng
AIM: To explore the association between contextual factors and periodontal disease. METHODS: We pooled individual-level data from 20,204 35-44-year-olds and 9,666 65-74-years-olds, who participated in the 3(rd) National Oral Health Survey in China (2005), with province-level data from different sources. The association of provincial macroeconomic factors (Gross Domestic Product [GDP] per capita and Gini coefficient), health resources (public health expenditure, dentist to population ratio and dental therapist to population ratio), demographic composition (proportion of rural population and minority ethnic groups) and tobacco industry (tobacco crops, cigarette production and proportion of smokers) with the numbers of teeth with periodontal pocket depth (PPD)>4mm and loss of attachment (LOA)>4mm were assessed in multilevel models, controlling for individual-level demographic, socioeconomic and behavioural factors...
October 5, 2016: Journal of Clinical Periodontology
Phillipa White, Dimitra Sakellari, Helen Roberts, Idyli Risafi, Martin Ling, Paul Cooper, Mike Milward, Iain Chapple
AIMS: To investigate ex vivo peripheral neutrophil extracellular trap (NET) production and their subsequent degradation by plasma in chronic periodontitis patients, and periodontally and systemically healthy-matched controls. MATERIALS AND METHODS: Chronic periodontitis patient and control (n=40 pairs) peripheral blood neutrophils were stimulated for NET quantification. A subset of patients received non-surgical periodontal therapy (n=19) and NETs were quantified 3-months later alongside controls...
September 28, 2016: Journal of Clinical Periodontology
Adriano Azaripour, Maren Kissinger, Vittorio Siro Leone Farina, Cornelis J F Van Noorden, Aslihan Gerhold-Ay, Brita Willershausen, Pierpaolo Cortellini
AIM: The aim of this randomized clinical trial was to compare the coronally advanced flap (CAF) with the modified microsurgical tunnel technique (MMTT) for treatment of Miller class I and II recessions. MATERIAL AND METHODS: 40 patients with 71 gingival recessions were recruited and randomly assigned to either CAF or to MMTT. In both groups a connective tissue graft was applied. Clinical evaluations were performed after 3, 6, and 12 months. Impressions were taken and digitally scanned 3-dimensionally to evaluate the quantitative soft tissue changes in the operative region...
September 26, 2016: Journal of Clinical Periodontology
Martina Stefanini, Karin Jepsen, Massimo de Sanctis, Nicola Baldini, Björn Greven, Bernd Heinz, Jan Wennström, Björn Cassel, Fabio Vignoletti, Mariano Sanz, Søren Jepsen, Giovanni Zucchelli
AIM: To assess patient-reported outcome measures (PROMs), aesthetics and stability of root coverage procedures from a previous 6-month RCT after 1 year. MATERIAL & METHODS: 45 patients (90 recessions) had received a coronally advanced flap (CAF = control) only or a xenogeneic collagen matrix in addition (CAF + CMX = test). Visual analogue scales (VAS) and questionnaires were used for PROMs and the root coverage aesthetic score (RES) for professional aesthetic evaluations...
September 22, 2016: Journal of Clinical Periodontology
Wim Slot, Gerry M Raghoebar, Marco S Cune, Arjan Vissink, Henny J A Meijer
OBJECTIVE: To compare a four- and six-implant maxillary overdenture after an observation period of 5 years. MATERIAL AND METHODS: Fifty subjects with functional problems concerning their maxillary denture, who had ample bone volume in the anterior region to place four or six implants, were included and randomly assigned to either group. Implant and overdenture survival, clinical performance, marginal bone loss and patient satisfaction were assessed. RESULTS: Forty-six patients completed the 5-year follow-up...
September 15, 2016: Journal of Clinical Periodontology
Eric Todd Scheyer, Rick Heard, Jim Janakievski, George Mandelaris, Marc L Nevins, Stephen R Pickering, Christopher R Richardson, Bryan Pope, Gregory Toback, Diego Velásquez, Heiner Nagursky
AIM: To compare the effectiveness of two-ridge preservation treatments. MATERIALS AND METHODS: Forty subjects with extraction sockets exhibiting substantial buccal dehiscences were enrolled and randomized across 10 standardized centres. Treatments were demineralized allograft plus reconstituted and cross-linked collagen membrane (DFDBA + RECXC) or deproteinized bovine bone mineral with collagen plus native, bilayer collagen membrane (DBBMC + NBCM). Socket dimensions were recorded at baseline and 6 months...
September 12, 2016: Journal of Clinical Periodontology
Daniel S Thoma, Monika Hilbe, Stefan Bienz, Manuel Sancho, Christoph H F Hämmerle, Ronald E Jung
AIM: To test whether or not a collagen matrix can improve early wound healing compared to spontaneous healing based on histologic and immunohistologic analyses. METHODS: In 20 volunteers, 6 mm punch biopsies were harvested at the palate. A xenogeneic collagen matrix (XCM) was sutured in one site; the other one was left untreated (control). Biopsies with a diameter of 8 mm were subsequently obtained at 4, 8, 15 and 29 days and histologic and immunohistologic analyses were performed...
September 12, 2016: Journal of Clinical Periodontology
Bernadette Pretzl, Peter Eickholz, Daniel Saure, Thorsten Pfefferle, Anna Zeidler, Bettina Dannewitz
OBJECTIVES: To assess the influence of endodontic status on retention of molars in patients under supportive periodontal treatment (SPT). MATERIAL & METHODS: A total of 136 subjects with 1015 molars at baseline were examined retrospectively, including 188 endodontically treated molars in 90 patients. Multilevel Cox regression analysis identified factors contributing to loss of molars. RESULTS: Root canal treatments contributed significantly to loss of molars during on average 13...
August 29, 2016: Journal of Clinical Periodontology
Dagmar F Bunaes, Stein Atle Lie, Anne Nordrehaug Åstrøm, Kamal Mustafa, Knut N Leknes
AIM: To evaluate the effect of cigarette smoking on periodontal health at patient, tooth, and site levels following supportive therapy. MATERIALS AND METHODS: Eighty chronic periodontitis patients, 40 smokers and 40 non-smokers, were recruited to a single-arm clinical trial. Periodontal examinations were performed at baseline (T0), 3 months following active periodontal therapy (T1), and 12 months following supportive periodontal therapy (T2). Smoking status was validated measuring serum cotinine levels...
August 24, 2016: Journal of Clinical Periodontology
Chih-Chun Mei, Fu-Ying Lee, Hwey-Chin Yeh
OBJECTIVE: To evaluate patients' pain perception following periodontal or implant surgery and to explore risk factors associated with post-surgical pain. MATERIALS AND METHODS: Patients undergoing periodontal or implant surgery were recruited. Post-surgical pain perception was evaluated by a numeric rating scale (NRS, 1 to 10) after one week. Self-reported durations of pain (DOP) and swelling (DOS), and consumption of prescriptions were also recorded. Demographic and surgical variables were compared between the groups of mild (MP) and moderate-to-severe post-surgical pain (SP)...
August 24, 2016: Journal of Clinical Periodontology
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