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Journal of Clinical Periodontology

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https://www.readbyqxmd.com/read/27891638/regenerative-potential-of-leucocyte-and-platelet-rich-fibrin-l-prf-part-b-sinus-floor-elevation-alveolar-ridge-preservation-and-implant-therapy-a-systematic-review
#1
REVIEW
Ana B Castro, Nastaran Meschi, Andy Temmerman, Nelson Pinto, Paul Lambrechts, Wim Teughels, Marc Quirynen
AIM: To analyse the effect of Leucocyte- and Platelet Rich Fibrin (L-PRF) on bone regeneration procedures and osseointegration. MATERIALS AND METHODS: An electronic and hand search was conducted in three databases (MEDLINE, EMBASE and Cochrane). Only randomised clinical trials, written in English where L-PRF was applied in bone regeneration and implant procedures, were selected. No follow-up restrictions were applied. RESULTS: A total of 14 articles were included and processed...
November 28, 2016: Journal of Clinical Periodontology
https://www.readbyqxmd.com/read/27883212/a-retrospective-study-on-periodontal-disease-progression-in-private-practice
#2
Luigi Nibali, Chuanming Sun, Aliye Akcalı, Xsuan Meng, Yu-Kang Tu, Nikos Donos
BACKGROUND: Only a handful of studies have assessed tooth loss risk in chronic periodontitis patients following active therapy and factors associated with it. AIMS: The aim of this retrospective study was to assess tooth loss in a cohort of chronic periodontitis patients undergoing maintenance care in a UK private practice setting. MATERIALS AND METHODS: One hundred chronic periodontitis patients treated with active periodontal therapy (APT) were followed up in supportive periodontal therapy (SPT) for at least 5 years...
November 24, 2016: Journal of Clinical Periodontology
https://www.readbyqxmd.com/read/27883211/tissue-changes-after-ridge-preservation-with-two-xenografts-preliminary-results-from-a-multicenter-randomized-controlled-clinical-trial
#3
Antonio Barone, Paolo Toti, Alessandro Quaranta, Fortunato Alfonsi, Alessandro Cucchi, Bruno Negri, Roberto Di Felice, Saverio Marchionni, Jose' Luis Calvo-Guirado, Ugo Covani, Ulf Nannmark
OBJECTIVES: To evaluate and compare clinical and histological changes after ridge preservation procedures with those of spontaneous healing. MATERIALS_AND_METHODS: Ninety patients were enrolled in the present randomized controlled clinical trial and underwent single-tooth extraction in the premolar/molar areas. Thirty sites were grafted with collagenated cortico-cancellous (coll), 30 sites with cortical (cort) porcine bone and 30 sites underwent natural healing. Primary (vertical and horizontal bone changes after 3-month) and secondary outcomes (histomorphometric after 3 months) were evaluated at implant placement...
November 24, 2016: Journal of Clinical Periodontology
https://www.readbyqxmd.com/read/27883203/impact-of-platform-switching-on-interproximal-bone-levels-around-8-5-mm-implants-in-the-posterior-region-5-year-results-from-a-randomized-clinical-trial
#4
Gerdien Telleman, Gerry M Raghoebar, Arjan Vissink, Henny J A Meijer
AIM: To assess the medium-term results of 8.5 mm implants supplied with a conventional platform-matched implant-abutment connection or a platform-switched design. MATERIALS & METHODS: Eighty patients with 1 or more missing teeth in the maxillary or mandibular posterior zone were randomly assigned for treatment with implants with a conventional (control group) or platform-switched (test group) implant-abutment connection. Follow-up visits were conducted 1 month, 1 year and 5 years after functional loading...
November 24, 2016: Journal of Clinical Periodontology
https://www.readbyqxmd.com/read/27883202/the-role-of-platelets-in-inflammatory-immune-responses-in-generalized-aggressive-periodontitis
#5
Yalin Zhan, Ruifang Lu, Huanxin Meng, Xian'e Wang, Xiaojun Sun, Jianxia Hou
AIM: To investigate the relationship between inflammatory markers and platelet size in generalized aggressive periodontitis (GAgP). MATERIAL AND METHODS: Periodontal, inflammatory, and platelet indices were compared between 59 GAgP patients and 59 healthy subjects. Gingival biopsies from 5 patients and 5 healthy subjects were examined by immunohistochemistry and electron microscopy. Changes in patient periodontal and platelet indices were re-evaluated at 3 months after periodontal therapy...
November 24, 2016: Journal of Clinical Periodontology
https://www.readbyqxmd.com/read/27883200/a-new-way-to-estimate-disease-prevalence-from-random-partial-mouth-samples
#6
John S Preisser, Sarah J Marks, Anne E Sanders, Aderonke A Akinkugbe, James D Beck
AIM: Standard partial-mouth estimators of chronic periodontitis that define an individual's disease status solely in terms of selected sites underestimate prevalence. This study proposes an improved prevalence estimator based on randomly sampled sites and evaluates its accuracy in a well characterized population cohort. METHODS: Importantly, this method does not require determination of disease status at the individual level. Instead, it uses a statistical distributional approach to derive a prevalence formula from randomly selected periodontal sites...
November 24, 2016: Journal of Clinical Periodontology
https://www.readbyqxmd.com/read/27859471/volumetric-changes-at-pontic-sites-with-or-without-soft-tissue-grafting-a-controlled-clinical-study-with-a-10-year-follow-up
#7
Stefan P Bienz, Irena Sailer, Ignacio Sanz-Martin, Ronald E Jung, Christoph H F Hämmerle, Daniel S Thoma
OBJECTIVE: to evaluate volumetric changes of soft tissues at pontic sites in patients treated with or without soft tissue grafting over an observation period of 10 years. MATERIALS AND METHODS: A total of 17 patients receiving a tooth-borne fixed dental prosthesis (FDP) were enrolled in this study. Nine patients received a subepithelial connective tissue graft at the pontic site (test). Eight patients continued without soft tissue grafting (control). Baseline impressions were taken after delivery of the final FDP and at 10 years...
November 17, 2016: Journal of Clinical Periodontology
https://www.readbyqxmd.com/read/27862138/risk-factors-in-periodontology-a-conceptual-framework
#8
Philippe Bouchard, Maria Clotilde Carra, Adrien Boillot, Francis Mora, Hélène Rangé
AIM: The present article aims to emphasize the concepts of causal chains and the causal network of risk factors in periodontitis. The definition and assessment of risk factors, risk indicators and predisposing factors are of paramount importance in the understanding of the pathogenesis of periodontitis, as well as in its prevention and treatment. MATERIALS AND METHODS: This is a narrative review focusing on two main questions: (1) what is a risk in periodontology? and (2) how can a risk be assessed? RESULTS: The probability of the occurrence of an adverse outcome following exposure is not sufficient to analyze the impact of a risk factor on the disease...
November 12, 2016: Journal of Clinical Periodontology
https://www.readbyqxmd.com/read/27801947/prevalence-of-periodontal-diseases-in-a-multicenter-cohort-of-perinatally-hiv-infected-and-hiv-exposed-and-uninfected-youth
#9
Mark I Ryder, Tzy-Jyun Yao, Jonathan S Russell, Anna-Barbara Moscicki, Caroline H Shiboski
AIMS: To compare the prevalence and severity of periodontal diseases between 180 perinatally HIV-infected (PHIV) and 118 perinatally HIV-exposed and uninfected (PHEU) youth in a cross-sectional study conducted at 11 clinical sites in the United States and Puerto Rico from the Adolescent Master Protocol study of the Pediatric HIV/AIDS cohort study (PHACS) network. METHODS: Several analyses were conducted, employing the current CDC/AAP classification for periodontitis and incorporating a definition of gingivitis based on a bleeding on probing (BOP) threshold, and analyses based on more detailed whole-mouth, intra-oral regionally, site-based and tooth-based criteria of BOP, plaque levels, pockets depths and clinical attachment levels...
November 1, 2016: Journal of Clinical Periodontology
https://www.readbyqxmd.com/read/27801940/prognostic-value-of-a-simplified-method-for-periodontal-risk-assessment-during-supportive-periodontal-therapy
#10
Leonardo Trombelli, Luigi Minenna, Luca Toselli, Antonio Zaetta, Luigi Checchi, Vittorio Checchi, Michele Nieri, Roberto Farina
AIM: to evaluate the association between risk scores generated with a simplified method for periodontal risk assessment (Perio Risk) and tooth loss as well as bone loss during supportive periodontal therapy (SPT). MATERIALS & METHODS: Data related to 109 patients (42 males; mean age: 42.2 ± 10.2 years, range 22-62) enrolled in a SPT program for a mean period of 5.6 years were retrospectively obtained at two specialist periodontal clinics. Patients were stratified according to Perio Risk risk score (on a scale from 1 - low risk to 5 - high risk) as calculated at the end of active periodontal therapy...
November 1, 2016: Journal of Clinical Periodontology
https://www.readbyqxmd.com/read/27790732/root-coverage-using-porcine-collagen-matrix-with-fibroblast-growth-factor-2-a-pilot-study-in-dogs
#11
Jae Kook Cha, Yoo-Kyung Sun, Jung-Seok Lee, Seong-Ho Choi, Ui-Won Jung
AIM: The aim of this study was to evaluate the effect of fibroblast growth factor-2 (FGF-2) in combination with porcine collagen matrix (CM) for coverage of gingival recession defects in dogs. MATERIALS AND METHODS: In five male mongrel dogs, labial gingival recession defects were surgically created in the lower-third incisors bilaterally. The defects were randomly assigned to the CM/FGF-2 group (experimental) or the CM-only group (control). Standardized clinical photographs and silicone impressions were taken at 4 and 16 weeks of healing to calculate the remaining recession area...
October 28, 2016: Journal of Clinical Periodontology
https://www.readbyqxmd.com/read/27783851/regenerative-potential-of-leucocyte-and-platelet-rich-fibrin-l-prf-part-a-intrabony-defects-furcation-defects-and-periodontal-plastic-surgery-a-systematic-review-and-meta-analysis
#12
REVIEW
Ana B Castro, Nastaran Meschi, Andy Temmerman, Nelson Pinto, Paul Lambrechts, Wim Teughels, Marc Quirynen
AIM: To analyse the regenerative potential of Leucocyte- and Platelet Rich Fibrin (L-PRF) during periodontal surgery. MATERIALS AND METHODS: An electronic and hand search were conducted in three databases. Only randomised clinical trials were selected and no follow-up limitation was applied. Pocket depth (PD), clinical attachment level (CAL), bone fill, keratinized tissue width (KTW), recession reduction, and root coverage (%) were considered as outcome. When possible, meta-analysis was performed...
October 26, 2016: Journal of Clinical Periodontology
https://www.readbyqxmd.com/read/27783846/periodontitis-is-not-associated-with-metabolic-risk-during-the-fourth-decade-of-life
#13
Dara M Shearer, W Murray Thomson, Jonathan M Broadbent, Jim Mann, Richie Poulton
AIM: To examine associations between periodontitis and developmental trajectories of glycated haemoglobin (HbA1c) during the third and fourth decades in an initially healthy sample. MATERIALS AND METHODS: HbA1c data collected at ages 26, 32 and 38 in the prospective Dunedin Multidisciplinary Health and Development Study were used to assign study members (n=893) to trajectories applying group-based trajectory modelling (GBTM). The model allowed the statistical linking of baseline demographic, smoking and waist-height ratio covariates to group membership probability; and added a time-varying covariate (periodontitis) to the trajectories themselves to examine whether events that occurred during the course of the trajectory altered its course...
October 26, 2016: Journal of Clinical Periodontology
https://www.readbyqxmd.com/read/27783845/cementogenesis-and-osteogenesis-in-periodontal-tissue-regeneration-by-recombinant-human-transforming-growth-factor-%C3%AE-3-a-pilot-study-in-papio-ursinus
#14
Ugo Ripamonti, Ruqayya Parak, Roland M Klar, Caroline Dickens, Therese Dix-Peek, Raquel Duarte
OBJECTIVES: The aim of this study was to investigate cementogenesis and alveolar bone induction during in vivo periodontal tissue regeneration upon implantation of hTGF-β3 in furcation defects of Papio ursinus and to evaluate the feasibility of gene expression studies. MATERIALS AND METHODS: Class II furcation defects (day 0) were prepared in mandibular first and second molars of three P. ursinus and on day 30 implanted with and without 75 μg hTGF-β3 in Matrigel(®) matrix...
October 26, 2016: Journal of Clinical Periodontology
https://www.readbyqxmd.com/read/27767222/long-term-clinical-response-to-treatment-and-maintenance-of-localized-aggressive-periodontitis-a-cohort-study
#15
Karina A F S Miller, Luciana S Branco-de-Almeida, Sandra Wolf, Nicole Hovencamp, Tina Treloar, Peter Harrison, Ikramuddin Aukhil, Yan Gong, Luciana M Shaddox
AIM: To evaluate long-term clinical response to periodontal therapy and maintenance in localized aggressive periodontitis (LAP). MATERIALS AND METHODS: One hundred forty-one African-Americans diagnosed with LAP, aged 5-25 years, were enrolled. Patients underwent periodontal mechanical debridement plus one week of amoxicillin/metronidazole. Mechanical therapy was repeated as needed and clinical parameters were recorded at baseline, 3, 6, 12, 18, and 24 months, and 2 additional annual follow-up visits after treatment...
October 21, 2016: Journal of Clinical Periodontology
https://www.readbyqxmd.com/read/27754553/host-genetics-role-in-the-pathogenesis-of-periodontal-disease-and-caries
#16
Luigi Nibali, Anna Di Iorio, Yu-Kang Tu, Alexandre R Vieira
BACKGROUND: This study aimed to produce the latest summary of the evidence for association of host genetic variants contributing to both periodontitis and caries. MATERIALS AND METHODS: Two systematic searches of the literature were conducted in Ovid Medline, Embase, LILACS and Cochrane Library for large candidate gene studies, systematic reviews and GWAS reporting data on host genetic variants and presence of periodontal disease and caries. RESULTS: A total of 124 studies were included in the review (59 for the periodontitis outcome and 68 for the caries outcome), from an initial search of 15,487 titles...
October 18, 2016: Journal of Clinical Periodontology
https://www.readbyqxmd.com/read/27736011/periodontal-regeneration-compared-with-access-flap-surgery-in-human-intra-bony-defects-20-year-follow-up-of-a-randomized-clinical-trial-tooth-retention-periodontitis-recurrence-and-costs
#17
Pierpaolo Cortellini, Jacopo Buti, Giovanpaolo Pini Prato, Maurizio S Tonetti
AIM: Compare the long-term outcomes and costs of three treatment modalities in intra-bony defects. MATERIALS AND METHODS: Forty-five intra-bony defects in 45 patients had been randomly allocated to receive: modified papilla preservation technique with titanium-reinforced expanded-polytetrafluoroethylene (ePTFE) membranes (MPPT Tit, N = 15); access flap with expanded-PTFE membranes (Flap-ePTFE, N = 15) and access flap alone (Flap, N = 15). Supportive periodontal care (SPC) was provided monthly for 1 year, then every 3 months for 20 years...
October 13, 2016: Journal of Clinical Periodontology
https://www.readbyqxmd.com/read/27726174/effectiveness-of-non-surgical-periodontal-therapy-in-a-large-chinese-population-with-chronic-periodontitis
#18
Jian Jiao, Dong Shi, Zhan-Qiang Cao, Huan-Xin Meng, Rui-Fang Lu, Li Zhang, Yi Song, Jing-Ren Zhao
AIM: To evaluate the effectiveness of non-surgical periodontal treatment (NSPT) and its influential factors in a large Chinese population with chronic periodontitis. METHODS: Periodontal examination data of 10,789 patients with at least one periodontal re-evaluation record were extracted from a hospital-based electronic periodontal charting record system. Probing depth (PD) and bleeding index (BI) reductions after NSPT and their influential factors were analyzed by multilevel analysis...
October 11, 2016: Journal of Clinical Periodontology
https://www.readbyqxmd.com/read/27717180/does-obesity-influence-the-subgingival-microbiota-composition-in-periodontal-health-and-disease
#19
Suellen Silva Maciel, Magda Feres, Tiago Eduardo Dias Gonçalves, Glaucia Santos Zimmermann, Hélio Doyle Pereira da Silva, Luciene Cristina Figueiredo, Poliana Mendes Duarte
AIM: To evaluate whether obesity affects the subgingival microbial composition of patients with periodontal health or chronic periodontitis (CP). MATERIALS AND METHODS: Based on periodontal parameters, body mass index and waist-hip ratio, 166 patients were allocated into one of the following groups: Normal weight (NW) patients with periodontal health (n = 44), NW patients with CP (n = 40), obese patients with periodontal health (n = 40) and obese patients with CP (n = 42)...
October 7, 2016: Journal of Clinical Periodontology
https://www.readbyqxmd.com/read/27716970/soft-tissue-volume-augmentation-at-dental-implant-sites-using-a-volume-stable-three-dimensional-collagen-matrix-histologic-outcomes-of-a-preclinical-study
#20
Daniel S Thoma, Nadja Naenni, Goran I Benic, Christoph H F Hämmerle, Ronald E Jung
AIM: To test whether or not soft tissue augmentation with a collagen matrix (VCMX) leads to a similar increase in ridge width around dental implants compared to the use of an autogenous subepithelial connective tissue graft (SCTG). MATERIALS AND METHODS: In 12 dogs, immediate dental implants were placed with simultaneous guided bone regeneration. Three months later, soft tissue volume augmentation was performed by randomly allocating three treatment modalities to these sites (VCMX, SCTG, sham-operated group (control))...
October 7, 2016: Journal of Clinical Periodontology
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