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Journal of Clinical Periodontology

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https://www.readbyqxmd.com/read/29655178/screening-of-candidate-biomaterials-for-alveolar-augmentation-using-a-critical-size-rat-calvaria-defect-model
#1
Cristiano Susin, Jaebum Lee, Tiago Fiorini, Ki-Tae Koo, Peter Schüpbach, Patricia D Melchiors Angst, Amanda Finger Stadler, Ulf Me Wikesjö
OBJECTIVE: To screen candidate biomaterials intended for alveolar augmentation relative to their potential to enhance local bone formation using a routine critical-size (ø8-mm) rat calvaria defect model. METHODS: One-hundred-and-forty, male, Sprague-Dawley outbred rats, age 11-12 wks, weight 325-375 g, obtained from USDA approved breeder, randomized into 14 groups of 10 animals, each received one of the following treatments: sham-surgery (empty control), Bio-Oss (bovine HA/reference control), or candidate biomaterials including bovine HA, synthetic HA/ß-TCP and calcium phosphate constructs, mineralized/demineralized human bone preparations, a ß-TCP/calcium sulfate and an HA/calcium sulfate putty...
April 14, 2018: Journal of Clinical Periodontology
https://www.readbyqxmd.com/read/29611224/self-report-assessment-of-severe-periodontitis-periodontal-screening-score-development
#2
Maria Clotilde Carra, Alice Gueguen, Frédérique Thomas, Bruno Pannier, Giuseppina Caligiuri, Philippe Gabriel Steg, Marie Zins, Philippe Bouchard
AIM: To derive from a validated questionnaire a periodontal screening score, intended as an user-friendly tool to identify individuals at risk of periodontitis in epidemiological studies. METHODS: A French 12-item self-reported questionnaire was developed by translating English questions previously used for periodontitis screening and surveillance. After a cognitive evaluation, the questionnaire was validated in a sample of 232 individuals (mean age: 46.1±12.6 years) receiving full-mouth periodontal examination, including probing pocket depth and clinical attachment level recordings...
April 3, 2018: Journal of Clinical Periodontology
https://www.readbyqxmd.com/read/29611221/5-year-rct-comparing-minimally-with-moderately-rough-implants-in-patients-with-severe-periodontitis
#3
M Raes, R D'hondt, W Teughels, W Coucke, M Quirynen
AIM: To compare the clinical and microbiological performance of minimally and moderately rough implants in patients with a history of severe periodontitis. MATERIAL AND METHODS: Forty-eight minimally (Tur) and moderately (TiU) rough implants were placed in eighteen patients according to a split-mouth protocol. Marginal bone loss, probing pocket depth (PPD), clinical attachment level (CAL), and bleeding on probing (BoP) were recorded, and microbial samples were analysed by means of quantitative PCR...
April 3, 2018: Journal of Clinical Periodontology
https://www.readbyqxmd.com/read/29611219/association-between-periodontal-disease-and-gestational-diabetes-mellitus-gdm-a-prospective-cohort-study
#4
Ashok Kumar, Deepika S Sharma, Mahesh Verma, Arundeep Kaur Lamba, Madhavi M Gupta, Shashi Sharma, Vanamail Perumal
AIM: The present study aims to determine the association between periodontal disease and gestational diabetes mellitus (GDM) and the effect of this association on pregnancy outcome in North Indian population. MATERIALS & METHODS: A total of 584 primigravidae were recruited at 12-14 weeks of gestation. Their periodontal examination was done along with 75g oral glucose load test at the time of recruitment. GDM was diagnosed as per the DIPSI (The Diabetes in Pregnancy Study group India) guidelines (≥140mg/dL)...
April 3, 2018: Journal of Clinical Periodontology
https://www.readbyqxmd.com/read/29611218/validation-of-multivariable-models-for-predicting-tooth-loss-in-periodontitis-patients
#5
F Schwendicke, E Schmietendorf, A Plaumann, S Sälzer, C E Dörfer, C Graetz
OBJECTIVES: A large number of multivariable models which associate independent variables with the outcome tooth loss exist. Directly or indirectly, these make predictions as to the relative risk of tooth loss. We aimed to validate six of these prediction models. METHODS: We applied each model, if needed after adaptions, in a cohort of 301 compliant periodontitis patients who had been under supportive periodontal treatment (SPT) in a university setting over 21.7±5...
April 3, 2018: Journal of Clinical Periodontology
https://www.readbyqxmd.com/read/29608804/relationship-between-vitamin-d-receptor-gene-polymorphism-and-susceptibility-to-chronic-kidney-disease-and-periodontal-disease-in-community-dwelling-elderly
#6
A Yoshihara, N Kaneko, M Iwasaki, K Nohno, H Miyazaki
OBJECTIVES: The aim of this study was to investigate the possible correlation between vitamin D receptor (VDR) gene polymorphism and susceptibility to chronic kidney disease (CKD) and periodontal disease. MATERIAL AND METHODS: This study analyzed 345 participants, who were all 79 years of age. Kidney function levels were determined based on the estimated glomerular filtration rate (eGFR) (non-reduced function: ≥60, and reduced function: <60 mL/min/1.73 m2 )...
April 2, 2018: Journal of Clinical Periodontology
https://www.readbyqxmd.com/read/29608793/a-randomized-controlled-study-on-the-accuracy-of-free-handed-pilot-drill-guided-and-fully-guided-implant-surgery-in-partially-edentulous-patients
#7
Faris Younes, Jan Cosyn, Thomas De Bruyckere, Roberto Cleymaet, Eline Bouckaert, Aryan Eghbali
AIM: To compare the accuracy of free-handed (FH), pilot-drill guided (PG) and fully-guided (FG) implant surgery. MATERIALS AND METHODS: Partially edentulous patients in need of ≥2 implants in the posterior maxilla were randomly allocated to one of the following treatment groups: FH, PG, FG. Ideal implant positions were determined in designated software following the fusion of bony information (CBCT data in DICOM format) to the prosthetic wax-up (optical scan data in STL format)...
April 2, 2018: Journal of Clinical Periodontology
https://www.readbyqxmd.com/read/29608788/a-retrospective-study-of-30959-implants-risk-factors-associated-with-early-and-late-implant-loss
#8
Guofen Lin, Shuhua Ye, Fengjia Liu, Fuming He
AIM: This retrospective study assessed the risk factors associated with early and late implant loss at the patient- and implant-based analysis. MATERIALS AND METHODS: A total of 18199 patients received 30959 dental implants during the years 2011-2015. Age, gender, jaw, location, implant brands, implant length and diameter, bone augmentation procedures, and the number of implants placed per patient were recorded. A multivariate generalized estimating equation (GEE) logistic regression was used to identify risk factors related to both early and late implant loss...
April 2, 2018: Journal of Clinical Periodontology
https://www.readbyqxmd.com/read/29608783/wild-type-isolates-of-porphyromonas-gingivalis-derived-from-periodontitis-patients-display-major-variability-in-platelet-activation
#9
Y Jockel-Schneider, A Kobsar, A Stellzig-Eisenhauer, U Vogel, S Störk, S Frantz, U Schlagenhauf, M Eigenthaler
In vitro studies revealed that Porphyromonas gingivalis (Pg), a pathogen intimately associated with the onset and progression of periodontitis, is able to activate platelets thus linking periodontal inflammation with the endangerment of vascular health. As wild-type Pg strains are characterized by major genetic heterogeneity, the commonness of platelet activating Pg strains in periodontitis patients is unknown as of yet. Therefore, this study evaluated the platelet activation capacity of wild-type Pg isolates sampled from patients with aggressive periodontitis...
April 2, 2018: Journal of Clinical Periodontology
https://www.readbyqxmd.com/read/29575189/appraisal-of-systematic-reviews-on-the-management-of-peri-implant-diseases-with-two-methodological-tools
#10
Clovis Mariano Faggion, Alberto Monje, Jason Wasiak
AIM: This study aimed to (a) to evaluate and compare the performance of two methodological instruments to appraise systematic reviews, and (b) to identify potential disagreements of systematic review authors regarding risk of bias (ROB) evaluation of randomized controlled trials (RCTs) included in systematic reviews on peri-implant diseases. MATERIAL/METHODS: We searched Medline, Web of Science databases, and Cochrane library for systematic reviews on peri-implant diseases published before July 11, 2017...
March 25, 2018: Journal of Clinical Periodontology
https://www.readbyqxmd.com/read/29575168/site-level-risk-predictors-of-peri-implantitis-a-retrospective-analysis
#11
Purnima S Kumar, Shareef M Dabdoub, Rachna Hegde, Nanditha Ranganathan, Angelo Mariotti
AIM: The goal of the present investigation was to identify site-level factors that might allow prognostication of individual implants in partially-dentate patients with multiple non-splinted restorations. METHODS: We analyzed clinical and radiographic characteristics of 222 non-splinted single implants in function for at least 5 years in 86 partially dentate individuals at the time of functional loading and at follow-up, with the outcome variable being peri-implantitis...
March 25, 2018: Journal of Clinical Periodontology
https://www.readbyqxmd.com/read/29574908/ppar%C3%AE-plays-dual-roles-on-experimental-periodontitis-in-rats
#12
Weiwei Qiao, Changning Wang, Wushuang Huang, Yingying Hu, Yaling Song
AIM: To investigate the effects of PPARγ on inflammation control and bone remodeling in experimental periodontitis in rats. MATERIALS AND METHODS: Experimental periodontitis was induced in rats by thread ligation around cervixes of mandibular first molars. PPARγ agonist, antagonist and vehicle were intraperitoneally administrated respectively into rats. 96 male SD rats were randomly divided into control, ligation+vehicle, ligation+agonist and ligation+antagonist groups...
March 25, 2018: Journal of Clinical Periodontology
https://www.readbyqxmd.com/read/29574866/surgical-treatment-of-peri-implantitis-using-enamel-matrix-derivative-an-rct-3-and-5-year-follow-up
#13
Catrine Isehed, Björn Svenson, Pernilla Lundberg, Anders Holmlund
OBJECTIVE: To assess the clinical and radiographic outcomes 3 and 5 years after the surgical treatment of peri-implantitis per se or in combination with an enamel matrix derivative (EMD). MATERIALS AND METHODS: At baseline, 29 patients were randomized to surgical treatment with adjunctive EMD or no EMD. One year after the surgical treatment of peri-implantitis, 25 patients remained eligible for survival analyses at the 3- and 5-year follow-up. The primary outcomes were implant loss and bone level (BL) change measured on radiographs, and the secondary outcomes, bleeding on probing, pus and plaque at each implant, were analyzed in 18 and14 patients at the 3- and 5-year follow-up, respectively...
March 25, 2018: Journal of Clinical Periodontology
https://www.readbyqxmd.com/read/29574852/early-and-late-implant-failure-of-submerged-versus-non-submerged-implant-healing-a-systematic-review-meta-analysis-and-trial-sequential-analysis
#14
REVIEW
Giuseppe Troiano, Lucio Lo Russo, Luigi Canullo, Domenico Ciavarella, Lorenzo Lo Muzio, Luigi Laino
INTRODUCTION: The aim of this systematic review is to analyze current evidence regarding differences in early and late implant failure as well as in marginal bone level (MBL) changes between submerged and non-submerged healed dental implants. METHODS: PUBMED, SCOPUS, EMBASE and Web of Science databases were searched for prospective randomized and non-randomized controlled studies addressing direct comparison between submerged and non-submerged implant healing, without performing immediate loading...
March 25, 2018: Journal of Clinical Periodontology
https://www.readbyqxmd.com/read/29517812/microrna-146a-and-microrna-155-as-novel-crevicular-fluid-biomarkers-for-periodontitis-in-nondiabetic-and-type-2-diabetic-patients
#15
Nikola Radović, Nataša Nikolić Jakoba, Nina Petrović, Aleksandra Milosavljević, Božidar Brković, Jelena Roganović
AIM: Recent studies point at the crucial role of epigenetic mechanisms in the development of multifactorial diseases such as periodontitis and diabetes mellitus (DM) type 2. In addition, circulatory microRNAs (miRs) have emerged as novel biomarkers for various diseases. Aim of this study was to investigate the levels of miR-146a and miR-155 and superoxide dismutase (SOD) activity in gingival crevicular fluid (GCF) of periodontitis patients with (CPDM) and without (CP) DM type 2 as well as in periodontally healthy, control groups (PHDM and PH, respectively)...
March 8, 2018: Journal of Clinical Periodontology
https://www.readbyqxmd.com/read/29505132/influence-of-implant-neck-surface-and-placement-depth-on-crestal-bone-changes-and-soft-tissue-dimensions-around-platform-switched-implants-a-histologic-study-in-dogs
#16
Cristina Valles, Xavier Rodriguez-Ciurana, Fernando Muñoz, Maria Permuy, Henar López-Alonso, Jose Nart
OBJECTIVES: To analyze bone remodeling and peri-implant soft tissues around platform-switching implants with and without a machined collar placed at different levels in relation to bone crest. MATERIAL AND METHODS: All mandibular premolars and the first molars were extracted in five dogs. At 6 months, six implants with and without a machined neck (MACH and GBAE implants, respectively) were randomly inserted in each hemimandible positioning the implant-abutment interface in either a supracrestal (+1...
March 5, 2018: Journal of Clinical Periodontology
https://www.readbyqxmd.com/read/29500839/green-tea-prevents-vascular-disturbs-and-attenuates-periodontal-breakdown-in-long-term-hyperglycemia-in-t1d-rats
#17
Daniela Pereira Catanzaro, Ever Elias Mena Laura, Tania M Cestari, Ricardo V N Arantes, Gustavo Pompermaier Garlet, Rumio Taga, Gerson Francisco de Assis
AIM: The effects of green tea on the modulation of vascularization during the progression of spontaneous periodontitis in long-term hyperglycemia in streptozotocin induced type-1 diabetic (T1D) rats were evaluated. MATERIALS AND METHODS: Wistar rats normoglycemic (NG) and T1D were divided in two control groups, which received water (NG-W and T1D-W) and two experimental groups that received green tea (NG-GT and T1D-GT). Periodontal structures were evaluated by microtomographic and histological analyzes...
March 3, 2018: Journal of Clinical Periodontology
https://www.readbyqxmd.com/read/29500837/investigation-of-factors-that-influence-pain-experienced-and-use-of-pain-medication-following-periodontal-surgery
#18
Jennifer R Beaudette, Peter C Fritz, Philip J Sullivan, Assunta Piccini, Wendy E Ward
AIMS: To determine the relationship between anticipated pain and actual pain experienced following soft tissue grafting or implant surgery; and to identify the factors that predict actual pain experienced and the use of pain medication following soft tissue grafting or implant surgery. MATERIALS AND METHODS: Prior to dental implant placement (n=98) or soft tissue grafting (n=115) and for seven days following the procedure, patients completed a visual analog scale indicating anticipated or experienced pain, respectively...
March 3, 2018: Journal of Clinical Periodontology
https://www.readbyqxmd.com/read/29500836/the-effect-of-decellularized-tissue-engineered-constructs-on-periodontal-regeneration
#19
A Farag, S M Hashimi, C Vaquette, P M Bartold, D W Hutmacher, S Ivanovski
AIM: To evaluate the effect of decellularized tissue engineered constructs on cell differentiation in vitro and periodontal regeneration in vivo. MATERIALS AND METHODS: Periodontal ligament cell (PDLC) sheets were loaded on polycaprolactone (PCL) scaffolds then decellularized. Constructs were assessed for their effect on allogenic PDLC and mesenchymal stem cell (MSC) differentiation in vitro, as evaluated by gene expression of bone and periodontal ligament tissue markers post-seeding...
March 3, 2018: Journal of Clinical Periodontology
https://www.readbyqxmd.com/read/29500831/mediation-analysis-of-systemic-inflammation-on-the-association-between-periodontitis-and-glycemic-status
#20
Kitti Torrungruang, Boonsong Ongphiphadhanakul, Supawadee Jitpakdeebordin, Somchai Sarujikumjornwatana
AIM: This cross-sectional study investigated the associations between periodontitis, systemic inflammation, and glycemic status. MATERIALS AND METHODS: The participants were divided into three groups: normoglycemia, impaired fasting glucose (IFG), and diabetes. Multinomial logistic regression was used to examine the associations between periodontitis severity and glycemic status, adjusting for potential confounders. Mediation analysis of four systemic inflammatory biomarkers, C-reactive protein (CRP), white blood cell count (WBC), neutrophil-lymphocyte ratio (NLR), and platelet-lymphocyte ratio (PLR), was performed...
March 3, 2018: Journal of Clinical Periodontology
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