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Journal of Clinical Periodontology

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https://www.readbyqxmd.com/read/28815664/simultaneous-lateral-bone-augmentation-and-implant-placement-using-a-particulated-synthetic-bone-substitute-around-chronic-peri-implant-dehiscence-defects-in-dogs
#1
Ui-Won Jung, Jae-Kook Cha, Fabio Vignoletti, Javier Nuñez, Javier Sanz, Mariano Sanz
AIM: To determine the histological outcomes when using a highly porous synthetic bone substitute and a cross-linked collagen membrane for lateral bone augmentation of peri-implant dehiscence defects. METHODS: In 8 dogs, three treatment groups were randomly allocated at each peri-implant dehiscence defect (mean height x depth = 3 x 1 mm): (i) synthetic bone substitute covered by a cross-linked collagen membrane (test group), (ii) deproteinized bovine bone mineral covered by a natural collagen membrane (positive control), and (iii) no treatment (negative control)...
August 16, 2017: Journal of Clinical Periodontology
https://www.readbyqxmd.com/read/28804947/periodontitis-and-non-alcoholic-fatty-liver-disease-a-population-based-cohort-investigation-in-the-study-of-health-in-pomerania
#2
Aderonke A Akinkugbe, Gary D Slade, A Sidney Barritt, Steven Offenbacher, Astrid Petersmann, Thomas Kocher, Markus M Lerch, Julia Mayerle, Henry Völzke, Gerardo Heiss, Birte Holtfreter
Non-alcoholic fatty liver disease (NAFLD) affects 20-30% of adults with risk factors like obesity and insulin resistance putatively acting through chronic low-grade inflammation. Because periodontitis elicits low-grade inflammation, we hypothesized that it could contribute to NAFLD occurrence. Objective To investigate epidemiologic associations between periodontitis and the incidence of NAFLD among 2,623 participants of the Study of Health in Pomerania METHODS: Periodontitis at baseline was defined as the percentage of sites (0%, 1-30%, ≥30%) with 1) clinical attachment level (CAL) ≥3mm; 2) probing pocket depth (PD) ≥4mm...
August 14, 2017: Journal of Clinical Periodontology
https://www.readbyqxmd.com/read/28800160/exercise-attenuates-alveolar-bone-loss-and-anxiety-like-behaviour-in-rats-with-periodontitis
#3
Eric F Andrade, Débora R Orlando, Júlia A S Gomes, Renata de C Foureaux, Rafael C Costa, Mary S Varaschin, Gustavo P Rogatto, Rodrigo F de Moura, Luciano J Pereira
AIM: To evaluate the effects of physical training on inflammatory and behavioral parameters of Wistar rats with periodontal disease (PD). MATERIALS AND METHODS: Twenty four animals were distributed in a 2x2 factorial design (with and without exercise, with and without PD). Trained animals swimmed one hour daily during eight weeks. PD was induced by ligature 14 days before the end of experiment and in the last week all animals were submitted to the Marble Burying Test...
August 11, 2017: Journal of Clinical Periodontology
https://www.readbyqxmd.com/read/28800151/cost-comparison-of-prediction-based-decision-making-for-periodontally-affected-molars
#4
Falk Schwendicke, Michael Stolpe, Christian Graetz
AIM: Tooth loss prediction could improve decision-making for periodontally-affected molars. We analyzed the costs of removing all, none or only those molars predicted to be at-risk for extraction during supportive periodontal therapy (SPT). METHODS: This is a model-based study using a German private-payer-perspective. Building mainly on cost and effectiveness data from 2039 molars (301 patients) which received long-term SPT, five (exemplary) prediction/decision strategies were compared: Retaining all molars, removing molars with furcation-involvement (FI) ≥I/≥II/III, or removing all molars...
August 11, 2017: Journal of Clinical Periodontology
https://www.readbyqxmd.com/read/28800147/reduction-in-bacteremia-after-brushing-with-a-triclosan-copolymer-dentifrice-a-randomized-clinical-study
#5
P K Sreenivasan, D Tischio-Bereski, D H Fine
AIM: The aims of this study were to; 1) test susceptibility to bacteremia in subjects with moderate gingivitis, and 2) compare the effects of brushing with a fluoride toothpaste (control) as compared to a triclosan/copolymer toothpaste (test) on those susceptible to repeated bacteremia. MATERIALS AND METHODS: 107 adult subjects were tested for repeated bacteremia after eating a hard apple. 29 bacteremia positive subjects were enrolled in a double-blind cross-over study designed to analyze the effects of a test toothpaste...
August 11, 2017: Journal of Clinical Periodontology
https://www.readbyqxmd.com/read/28800146/the-relationship-between-open-versus-normal-contact-point-and-inter-proximal-papilla-dimensions-in-periodontally-healthy-young-adults-a-controlled-clinical-trial
#6
Ronaldo Barcellos de Santana, Jose Luis Carneiro de Miranda, Carolina Miller Mattos de Santana
AIM: The gingival architecture is determined by the spatial orientation of the gingival zenith (GZ) and the interdental papillae (IP). Among the factors commonly associated with the presence and morphology of the IP, the contact point (CP) and the interdental distance relationships have been considered the most important. The objective of the present controlled clinical trial was to evaluate the role of the CP in determining the clinical and morphometric parameters of the interdental papilla...
August 11, 2017: Journal of Clinical Periodontology
https://www.readbyqxmd.com/read/28800144/at-least-three-phenotypes-exist-among-periodontitis-patients
#7
Chryssa Delatola, Bruno G Loos, Evgeni Levin, Marja L Laine
AIM: To identify phenotypes of periodontitis patients by the use of an unsupervised modeling technique (clustering), based on pre-treatment radiographic and microbiological characteristics. MATERIALS AND METHODS: This retrospective study included data from 392 untreated periodontitis patients. Co-regularized spectral clustering algorithm was used to cluster the patients. The resulting clusters were subsequently characterized based on their demographics, radiographic bone loss patterns and microbial data...
August 11, 2017: Journal of Clinical Periodontology
https://www.readbyqxmd.com/read/28796888/a-double-masked-rct-comparing-four-periodontitis-treatment-strategies-5-year-clinical-results
#8
Hans R Preus, Per Gjermo, Vibeke Baelum
AIM: To test the hypothesis of no difference in the 5-year clinical outcome of therapy between groups of patients treated with conventional over-weeks scaling and root planing or same-day full-mouth-disinfection, with or without adjunctive metronidazole. MATERIALS AND METHODS: Following a three-month oral hygiene phase, 184 periodontitis patients were randomly allocated to one of four treatment regimens 1) full mouth disinfection+metronidazole, 2) full mouth disinfection+placebo, 3) scaling and root planing+metronidazole, 4) scaling and root planing+placebo...
August 10, 2017: Journal of Clinical Periodontology
https://www.readbyqxmd.com/read/28782128/serum-lipid-levels-in-patients-with-periodontal-disease-a-meta-analysis-and-meta-regression
#9
REVIEW
Rafael Nepomuceno, Suzane C Pigossi, Livia S Finoti, Silvana R P Orrico, Joni A Cirelli, Silvana P Barros, Steven Offenbacher, Raquel M Scarel-Caminaga
AIM: Several papers have considered the potential relationship between periodontitis and lipid parameters. The present systematic review, meta-analysis and meta-regression study focused on investigating whether serum lipid parameter levels were elevated in patients with periodontal disease (PD) (without altered systemic conditions) in comparison with periodontally healthy subjects. MATERIALS AND METHODS: Eligible studies were those with data about serum lipid parameter levels in non-smoking subjects with and without chronic periodontitis, who are generally healthy and not taking any medication for dyslipidemia...
August 7, 2017: Journal of Clinical Periodontology
https://www.readbyqxmd.com/read/28771794/vertical-sub-classification-predicts-survival-of-molars-with-class-ii-furcation-involvement-during-supportive-periodontal-care
#10
Maurizio S Tonetti, Allis L Christiansen, Pierpaolo Cortellini
BACKGROUND: Furcation involvement is a major predictor of tooth survival. Focus has so far been on the predictive value of the horizontal component of furcation involvement. Residual periodontal support on each of the roots is likely to play a major role on retention of the furcated molar. Aim of this clinical audit study is to preliminarily assess the impact of vertical sub-classification on tooth retention. METHODS: Tooth retention of class II furcated molars in 200 consectutive patients compliant with periodontal supportive care for a minimum of 10 years was retrospectively evaluated in a single practice...
August 3, 2017: Journal of Clinical Periodontology
https://www.readbyqxmd.com/read/28766745/exploring-the-microbiome-of-healthy-and-diseased-peri-implant-sites-using-illumina-sequencing
#11
I Sanz-Martin, J Doolittle-Hall, R P Teles, M Patel, G N Belibasakis, C H Hämmerle, R E Jung, F R F Teles
AIM: To compare the microbiome of healthy (H) and diseased (P) peri-implant sites and determine the core peri-implant microbiome. MATERIALS AND METHODS: Submucosal biofilms from 32 H and 35 P sites were analyzed using 16S rRNA sequencing (MiSeq, Illumina), QIIME and HOMINGS. Differences between groups were determined using Principal Coordinate Analysis (PCoA), t-tests and Wilcoxon rank sum test and FDR-adjusted. The peri-implant core microbiome was determined. RESULTS: PCoA showed partitioning between H and P at all taxonomic levels...
August 2, 2017: Journal of Clinical Periodontology
https://www.readbyqxmd.com/read/28766735/relationship-between-tooth-loss-and-peripheral-arterial-disease-among-women
#12
Francisco J Muñoz-Torres, Kenneth J Mukamal, Jennifer K Pai, Walter Willett, Kaumudi J Joshipura
AIM: We assessed the longitudinal association between tooth loss and peripheral arterial disease (PAD) within the Nurses' Health Study. MATERIALS AND METHODS: After excluding participants with prior cardiovascular diseases, 277 out of 79,680 women were confirmed as PAD cases during 16-years of follow-up. Number of teeth and recent tooth loss were reported initially in 1992. Subsequent tooth loss was recorded in 1996 and in 2000. We evaluated the associations of baseline number of teeth and recent tooth loss with risk of PAD, adjusting for age, smoking, diabetes, hypertension, high cholesterol, aspirin use, family history of myocardial infarction, BMI, alcohol consumption, physical activity, post-menopausal hormone use, and use of vitamin E, vitamin D, multivitamin, and calcium...
August 2, 2017: Journal of Clinical Periodontology
https://www.readbyqxmd.com/read/28749582/is-periodontitis-associated-with-halitosis-a-systematic-review-and-meta-regression-analysis
#13
REVIEW
Manuela F Silva, Mariana G Cademartori, Fábio R M Leite, Rodrigo López, Flávio F Demarco, Gustavo G Nascimento
AIM: To systematically review the literature in order to investigate a potential association between periodontitis and halitosis. METHODS: Electronic searches were performed in four different databases: PubMed, Scopus, Web of Science and Scielo. Population based observational studies that tested the association between periodontitis and halitosis were included. Additionally, meta-analysis, meta-regression and subgroup analyses were performed to synthesize the evidence...
July 27, 2017: Journal of Clinical Periodontology
https://www.readbyqxmd.com/read/28746780/kava-241-reduced-periodontal-destruction-in-a-collagen-antibody-primed-porphyromonas-gingivalis-model-of-periodontitis
#14
Abdulsalam Alshammari, Jayesh Patel, Jacob Al-Hashemi, Bin Cai, James Panek, Olivier Huck, Salomon Amar
AIM: The aim of this study was to evaluate the effect of Kava-241, an optimized Piper methysticum Kava compound, on periodontal destruction in a collagen antibody primed oral gavage model of periodontitis. METHODS: Experimental periodontitis was induced by oral gavage of Porphyromonas gingivalis (P.gingivalis) + type-II collagen antibody (AB) in mice during 15 days. Mice were treated with Kava-241 concomitantly or prior to P.gingivalis gavage and compared to untreated mice...
July 26, 2017: Journal of Clinical Periodontology
https://www.readbyqxmd.com/read/28746727/idiopathic-male-infertility-related-to-periodontal-and-caries-status
#15
Nándor Práger, Norbert Pásztor, Ákos Várnagy, Zoltan Kozinszky, Zoltán Baráth, István Gorzó, Márta Radnai
OBJECTIVES: The present study was undertaken to evaluate the possible correlation between the periodontal and dental status and sperm pathology in idiopathic male infertility. METHODS: The periodontal and caries status and semen quality of 199 men presented with unexplained male infertility were examined. Periodontal and dental factors were analyzed by sperm pathology categories. RESULTS: 106 men had normal sperm parameters, whereas 93 men had some type of spermpathology; 27...
July 26, 2017: Journal of Clinical Periodontology
https://www.readbyqxmd.com/read/28736819/evaluation-of-dna-methylation-of-inflammatory-genes-following-treatment-of-chronic-periodontitis-a-pilot-case-control-study
#16
Farah Asa'ad, Valentina Bollati, Giorgio Pagni, Rogerio M Castilho, Eleonora Rossi, Francesca Pomingi, Letizia Tarantini, Dario Consonni, William V Giannobile, Giulio Rasperini
OBJECTIVE: To evaluate the influence of periodontal therapy on DNA methylation in chronic periodontitis patients as compared to healthy individuals. MATERIALS & METHODS: Twenty patients were enrolled into two groups: 1) 10 diagnosed as clinically healthy; and 2) 10 diagnosed with chronic periodontitis. Clinical measures were recorded and gingival biopsies were harvested at baseline (both patient groups) and at 2 and 8 weeks post-baseline for diseased individuals...
July 24, 2017: Journal of Clinical Periodontology
https://www.readbyqxmd.com/read/28733997/natural-history-of-periodontitis-disease-progression-and-tooth-loss-over-40-years
#17
C A Ramseier, Å Ånerud, M Dulac, M Lulic, M P Cullinan, G J Seymour, M J Faddy, W Büergin, M Schätzle, N P Lang
OBJECTIVES: To assess long-term attachment and periodontitis-related tooth loss (PTL) in untreated periodontal disease over 40 years. MATERIAL AND METHODS: Data originated from the natural history of periodontitis study in Sri Lankan tea labourers first examined in 1970. In 2010, 75 subjects (15.6%) of the original cohort were re-examined. RESULTS: PTL over 40 years varied between 0 and 28 teeth (mean 13.1). Four subjects presented with no PTL while 12 were edentulous...
July 22, 2017: Journal of Clinical Periodontology
https://www.readbyqxmd.com/read/28727170/entire-papilla-preservation-technique-in-the-regenerative-treatment-of-deep-intrabony-defects-1-year-results
#18
Serhat Aslan, Nurcan Buduneli, Pierpaolo Cortellini
AIM: This study evaluates the clinical performance of a novel tunnel-like surgical technique in the treatment of isolated deep intrabony defects. MATERIAL AND METHODS: Twelve patients presenting with at least one isolated deep intrabony defect received regenerative periodontal treatment with "entire papilla preservation" technique. Access to the intrabony defect for debridement was provided by a bevelled vertical releasing incision positioned in the buccal gingiva of the neighbouring interdental space...
July 20, 2017: Journal of Clinical Periodontology
https://www.readbyqxmd.com/read/28727164/the-innate-host-response-in-caries-and-periodontitis
#19
Joerg Meyle, Henrik Dommisch, Sabine Groeger, Rodrigo A Giacaman, Massimo Costalonga, Mark Herzberg
Innate immunity rapidly defends the host against infectious insults. These reactions are of limited specificity and exhaust without providing long-term protection. Functional fluids and effector molecules contribute to the defence against infectious agents, drive the immune response, and direct the cellular players. AIM: To review the literature and present a summary of current knowledge about the function of tissues, cellular players and soluble mediators of innate immunity relevant to caries and periodontitis...
July 20, 2017: Journal of Clinical Periodontology
https://www.readbyqxmd.com/read/28727160/the-long-term-effect-of-a-zinc-acetate-and-chlorhexidine-diacetate-containing-mouth-rinse-on-intra-oral-halitosis-a-randomized-clinical-trial
#20
Seida Erovic Ademovski, Carina Mårtensson, G Rutger Persson, Stefan Renvert
AIM: To evaluate the long-term effects of a zinc acetate and chlorhexidine diacetate mouth rinse (Zn/CHX) on intra-oral halitosis. MATERIALS AND METHODS: Forty-six adults with intra-oral halitosis were randomized into a 6-month, double-blind, placebo-controlled clinical study. The presence of intra-oral halitosis was evaluated at baseline, 3, and 6 months after treatment by assessment of organoleptic score (OLS) and by total volatile sulphur compounds (T-VSC), hydrogen sulphide (H2 S) and methyl mercaptan (MM) concentrations in exhaled air...
July 20, 2017: Journal of Clinical Periodontology
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