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Journal of Clinical Periodontology

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https://www.readbyqxmd.com/read/28092104/quantitative-proteomic-analysis-of-gingival-crevicular-fluids-from-deciduous-and-permanent-teeth
#1
Yumi Moriya, Takashi Obama, Toshihiro Aiuchi, Tomomi Sugiyama, Yumiko Endo, Yoko Koide, Emiko Noguchi, Motonori Ishizuka, Mitsuko Inoue, Hiroyuki Itabe, Matsuo Yamamoto
AIM: Gingivitis commonly progresses to periodontitis in permanent dentition but rarely in deciduous teeth. Little is known about the biochemical differences between gingiva of deciduous and permanent teeth. Here we compared the protein profiles of gingival crevicular fluids (GCF) from the gingiva of deciduous and permanent teeth. MATERIALS AND METHODS: Forty children with mixed dentition (Hellman's dental age IIIA) were selected and GCF samples were collected from deciduous cuspids and central incisors in the maxilla...
January 16, 2017: Journal of Clinical Periodontology
https://www.readbyqxmd.com/read/28081288/short-dental-implants-6-mm-versus-long-dental-implants-11-15-mm-in-combination-with-sinus-floor-elevation-procedures-3-year-results-from-a-multi-center-randomized-controlled-clinical-trial
#2
Veronika Pohl, Daniel S Thoma, Katarzyna Sporniak-Tutak, Abel Garcia-Garcia, Thomas D Taylor, Robert Haas, Christoph H F Hämmerle
AIM: To test whether or not the use of short dental implants (6 mm) results in an implant survival rate similar to that with longer implants (11-15 mm) in combination with sinus grafting. METHODS: This multi-center study enrolled 101 patients with partial edentulism in the posterior maxilla and a remaining bone height of 5-7 mm. Included patients were randomly assigned to receive short implants (6 mm; GS / group short) or long implants (11-15 mm) simultaneously with sinus grafting (GG / group graft)...
January 12, 2017: Journal of Clinical Periodontology
https://www.readbyqxmd.com/read/28063250/comparative-3d-micro-ct-and-2d-histomorphometry-analysis-of-dental-implant-osseointegration-in-the-maxilla-of-minipigs
#3
Oliver Bissinger, Florian Andreas Probst, Klaus-Dietrich Wolff, Anke Jeschke, Jochen Weitz, Herbert Deppe, Andreas Kolk
AIM: The bone implant contact (BIC) has traditionally been evaluated with histological methods. Thereupon, strong correlations of 2-dimensional (2D) BIC have been detected between μCT and destructive histology. However, due to the high intra-sample variability of BIC values, one histological slice is not sufficient to represent 3D BIC. Therefore, our aim has been to correlate the averaged values of 3-4 histological sections to 3D μCT. MATERIAL AND METHODS: Fifty four implants inserted into the maxilla of 14 minipigs were evaluated...
January 7, 2017: Journal of Clinical Periodontology
https://www.readbyqxmd.com/read/28036117/gingivitis-and-lifestyle-influences-on-hs-crp-and-il6-in-adolescents
#4
Vinay Pitchika, Elisabeth Thiering, Isabel Metz, Katrin Rothmaier, Anja Willenberg, Reinhard Hickel, Marie Standl, Thomas Kocher, Joachim Heinrich, Jan Kühnisch
AIM: This cross-sectional study was repeated at two time points and investigated the influence of gingivitis, smoking and body mass index (BMI) on the systemic inflammatory markers high-sensitivity C-reactive protein (hs-CRP) and interleukin 6 (IL6) in 10- and 15-year-olds. MATERIALS AND METHODS: The study sample of two birth cohorts, i.e., GINIplus and LISAplus, from the Munich centre consisted of 806 and 846 subjects who were evaluated at 10- and 15-year follow-ups, respectively...
December 30, 2016: Journal of Clinical Periodontology
https://www.readbyqxmd.com/read/28036104/periodontitis-and-incident-type-2-diabetes-a-prospective-cohort-study
#5
Lewis Winning, Christopher C Patterson, Charlotte E Neville, Frank Kee, Gerard J Linden
OBJECTIVES: To investigate periodontitis as a risk factor for incident type 2 diabetes mellitus (T2DM) in a group of men aged 58-72 years. METHODS: 1331 dentate, diabetes-free males in Northern Ireland underwent a detailed periodontal examination during 2001-2003. Follow-up was by bi-annual questionnaire and for those reporting diabetes their general medical practitioner was contacted to validate diabetes type, treatment and diagnosis date. Cox's proportional hazard models were used to estimate the effect of periodontitis on incident diabetes...
December 30, 2016: Journal of Clinical Periodontology
https://www.readbyqxmd.com/read/28032908/adjunctive-efficacy-of-probiotics-in-the-treatment-of-experimental-peri-implant-mucositis-with-mechanical-and-photodynamic-therapy-a-randomized-cross-over-clinical-trial
#6
Claudio Mongardini, Andrea Pilloni, Roberto Farina, Gianluca Di Tanna, Blerina Zeza
AIM: to evaluate the adjunctive clinical efficacy of probiotics in the treatment of peri-implant mucositis (p-iM) with professionally administered plaque removal (PAPR) and photodynamic therapy (PDT). MATERIALS AND METHODS: Following p-iM induction, patients underwent PAPR+PDT and were randomly assigned to receive the professional and home-based administration of probiotics (Lactobacillus plantarum and Lactobacillus brevis) (test treatment) or placebo preparation (control treatment) according to a cross-over design...
December 29, 2016: Journal of Clinical Periodontology
https://www.readbyqxmd.com/read/28032906/3-dimensional-functionalized-polycaprolactone-hyaluronic-acid-hydrogel-constructs-for-bone-tissue-engineering
#7
Stephen M Hamlet, Cedryck Vaquette, Amit Shah, Dietmar W Hutmacher, Saso Ivanovski
AIM: Alveolar bone regeneration remains a significant clinical challenge in periodontology and dental implantology. This study assessed the mineralized tissue forming potential of 3D printed medical grade polycaprolactone (mPCL) constructs containing osteoblasts encapsulated in a hyaluronic acid (HA) hydrogel incorporating bone morphogenetic protein-7 (BMP-7). MATERIALS AND METHODS: HA-hydrogels containing human osteoblasts ± BMP-7 were prepared. Cell viability, osteogenic gene expression, mineralized tissue formation and BMP-7 release in vitro, were assessed by fluorescence staining, RT-PCR, histological / μ-CT examination and ELISA respectively...
December 29, 2016: Journal of Clinical Periodontology
https://www.readbyqxmd.com/read/28032903/serum-lipids-modify-periodontal-infection-interleukin-6-association
#8
Anniina Haro, Tuomas Saxlin, Anna Liisa Suominen, Antti Jula, Matti Knuuttila, Pekka Ylöstalo
AIM: To investigate whether the systemic response against a local inflammatory process in periodontium is dependent on the individual's serum lipid composition. MATERIAL AND METHODS: This study was based on a subpopulation of the Health 2000 Survey that included 878 subjects who were aged between 45 and 64 years, dentate, non-diabetic and non-rheumatic. The inflammatory condition of periodontium was measured by means of the number of teeth with deepened (4 mm or deeper) periodontal pockets...
December 29, 2016: Journal of Clinical Periodontology
https://www.readbyqxmd.com/read/28028838/long-term-tooth-retention-in-chronic-periodontitis-results-after-18%C3%A2-years-of-a-conservative-periodontal-treatment-regimen-in-a-university-setting
#9
Christian Graetz, Anna Plaumann, Peter Schlattmann, Maren Kahl, Claudia Springer, Sonja Sälzer, Konstantin Gomer, Christof Dörfer, Falk Schwendicke
AIM: The longitudinal study assessed the risk of tooth loss under a non-regenerative treatment regimen and aimed to identify prognostic factors for tooth loss. METHODS: Three hundred and fifteen patients (8009 teeth) were examined before (T0) and after active periodontal therapy (APT, T1) as well as after (mean ± SD) 18 ± 6 years of supportive periodontal therapy (SPT, T2). Descriptive statistics and a Cox proportional hazards shared-frailty model were applied...
December 27, 2016: Journal of Clinical Periodontology
https://www.readbyqxmd.com/read/28028834/the-association-between%C3%A2-undiagnosed-glycemic-abnormalities-and-cardiometabolic-risk-factors-with-periodontitis-results-from-2007-2009-canadian-health-measures-survey
#10
Aleksandra Zuk, Carlos Quiñonez, Michael Lebenbaum, Laura C Rosella
AIM: The aim was to investigate the association between undiagnosed glycemic abnormalities and cardiometabolic risk factors with periodontitis. METHODS: Using Cycle 1 (2007 to 2009) of Canadian Health Measures Survey, survey-sampling weights were applied to a restricted sample of fasting, non-pregnant adults between 19 - 79 years of age without diagnosed or treated type-2 diabetes. We estimated the prevalence of periodontitis, and various cardiometabolic risk factors according to the clinical diagnostic definition for metabolic syndrome (MetS), recognized by the American Heart Association and National Heart, Lung, and Blood Institute...
December 27, 2016: Journal of Clinical Periodontology
https://www.readbyqxmd.com/read/28005268/health-information-quality-of-websites-on-periodontology
#11
Isabella Bizzi, Pietro Ghezzi, Priyamvada Paudyal
AIM: This study aimed to assess the quality of the information available on the Web on gum disease. METHODS: The term 'gum disease' was searched in Google and in MedlinePlus. The first 200 websites were analysed by the Journal of the American Medical Association (JAMA) criteria and the Health On the Net Foundation (HONCode) certification, instruments for assessing quality of health information. Data was analysed through the Mann-Whitney test or Kruskal-Wallis test, followed by the Dunn's test, using the GraphPad Prism Software version 6...
December 22, 2016: Journal of Clinical Periodontology
https://www.readbyqxmd.com/read/28005267/human-gingiva-transcriptome-during-wound-healing
#12
Yun Wang, Dimitris N Tatakis
OBJECTIVES: To investigate the gene expression profile of human gingiva following surgical wounding. METHODS: Ten volunteers had one side of the palate wounded. Five days later, biopsies were harvested from both wounded (healing gingiva) and contralateral site (normal gingiva). Tissue samples were processed for gene expression (RNA-Seq, real-time PCR) and immuno-histochemistry. Gene-set enrichment/pathway analysis was also performed. RESULTS: Seven hundred genes were significantly differentially expressed in healing gingiva...
December 22, 2016: Journal of Clinical Periodontology
https://www.readbyqxmd.com/read/28005264/mucin-4-and-matrix-metalloproteinase-7-as-novel-salivary-biomarkers-for-periodontitis
#13
Anna Lundmark, Gunnar Johannsen, Kaja Eriksson, Anna Kats, Leif Jansson, Taina Tervahartiala, Nilminie Rathnayake, Sigvard Åkerman, Björn Klinge, Timo Sorsa, Tülay Yucel-Lindberg
AIM: Periodontitis is a chronic inflammatory disease, characterized by irreversible destruction of tooth-supporting tissue including alveolar bone. We recently reported mucin 4 (MUC4) and matrix metalloproteinase 7 (MMP7) as highly associated with periodontitis in gingival tissue biopsies. The aim of this study was to further investigate the levels of MUC4 and MMP7 in saliva and gingival crevicular fluid (GCF) samples of patients with periodontitis. MATERIALS AND METHODS: Saliva and GCF samples were collected from periodontitis patients and healthy controls...
December 22, 2016: Journal of Clinical Periodontology
https://www.readbyqxmd.com/read/27978604/effects-of-emd-liquid-osteogain-on-periodontal-healing-in-class-iii-furcation-defects-in-monkeys
#14
Yoshinori Shirakata, Richard J Miron, Toshiaki Nakamura, Kotaro Sena, Yukiya Shinohara, Naoto Horai, Dieter D Bosshardt, Kazuyuki Noguchi, Anton Sculean
AIM: To evaluate the effect of a novel liquid carrier system of enamel matrix derivative (Osteogain) soaked on an absorbable collagen sponge (ACS) upon periodontal wound healing/regeneration in furcation defects in monkeys. MATERIALS AND METHODS: The stability of the conventional enamel matrix derivative (Emdogain) and Osteogain adsorbed onto ACS was evaluated by ELISA. Chronic class III furcation defects were created at teeth 36, 37, 46, 47 in three monkeys (Macaca fascicularis)...
December 15, 2016: Journal of Clinical Periodontology
https://www.readbyqxmd.com/read/27978603/clinical-and-radiographic-intra-subject-comparison-of-implants-placed-with-or-without-guided-bone-regeneration-15-year-results
#15
Goran I Benic, Mira Bernasconi, Ronald E Jung, Christoph H F Hämmerle
AIM: To test whether implants placed with simultaneous guided bone regeneration (GBR) differ from implants placed without GBR regarding survival rate, interproximal marginal bone level (MBL), and dimensions of buccal bone and mucosa. MATERIAL & METHODS: Twenty-three patients treated 15 years earlier were included. Machined implants had been inserted following one of the two procedures: (1) with simultaneous GBR, which involved grafting with particulate deproteinized bovine bone mineral (DBBM), autogenous bone (AB) or a mixture of the two and defect covering with a native collagen membrane (CM), (GBR group) and (2) standard implant placement without GBR (control group)...
December 15, 2016: Journal of Clinical Periodontology
https://www.readbyqxmd.com/read/27978602/immediate-vs-delayed-implant-placement-after-anterior-single-tooth-extraction-the-timing-randomised-controlled-clinical-trial
#16
Maurizio S Tonetti, Pierpaolo Cortellini, Filippo Graziani, Francesco Cairo, Niklaus P Lang, Roberto Abundo, Gian Paolo Conforti, Siegfried Marquardt, Giulio Rasperini, Maurizio Silvestri, Beat Wallkamm, Anton Wetzel
AIM: to compare need for bone augmentation, surgical complications, periodontal, radiographic, aesthetic and patient reported outcomes in subjects receiving implant placement at the time of extraction (IMI) or 12 weeks thereafter. METHODS: Subjects requiring single tooth extraction in the anterior and premolar areas were recruited in 7 private practices. Implant position and choice of platform were restoratively driven. Measurements were performed by calibrated and masked examiners...
December 15, 2016: Journal of Clinical Periodontology
https://www.readbyqxmd.com/read/27978601/cross-sectional-associations-of-impaired-glucose-metabolism-measures-with-bleeding-on-probing-and-periodontitis
#17
Cynthia M Pérez, Francisco Muñoz, Oelisoa M Andriankaja, Christine S Ritchie, Sasha Martínez, José Vergara, José Vivaldi, Lydia López, Maribel Campos, Kaumudi J Joshipura
AIM: This study assessed the associations of pre-diabetes and insulin resistance with bleeding on probing (BOP) and periodontitis among adults. MATERIALS AND METHODS: We included 1191 Hispanic adults aged 40-65 years, free of diabetes, enrolled in San Juan Overweight Adults Longitudinal Study. Pre-diabetes was defined as impaired fasting glucose (IFG), impaired glucose tolerance (IGT), or impaired glycated haemoglobin. Impaired one-hour plasma glucose (1hPG) was defined as levels >155 mg/dl...
December 15, 2016: Journal of Clinical Periodontology
https://www.readbyqxmd.com/read/27978598/the-subgingival-microbiome-systemic-inflammation-and-insulin-resistance-the-oral-infections-glucose-intolerance-and-insulin-resistance-study-origins
#18
Ryan T Demmer, Alexander Breskin, Michael Rosenbaum, Aleksandra Zuk, Charles LeDuc, Rudolph Leibel, Bruce Paster, Moïse Desvarieux, David R Jacobs, Panos N Papapanou
BACKGROUND: Inflammation might link microbial exposures to insulin resistance. We investigated the cross-sectional association between periodontal microbiota, inflammation and insulin resistance. METHODS: The Oral Infections, Glucose Intolerance and Insulin Resistance Study (ORIGINS) enrolled 152 diabetes-free adults (77% female) aged 20-55 years (mean=34±10). 304 subgingival plaque samples were analyzed using the Human Oral Microbe Identification Microarray to measure the relative abundances of 379 taxa...
December 15, 2016: Journal of Clinical Periodontology
https://www.readbyqxmd.com/read/27930822/estimating-effects-of-craniofacial-morphology-on-gingival-recession-and-clinical-attachment-loss
#19
Loutfi Salti, Birte Holtfreter, Christiane Pink, Mohamad Habes, Reiner Biffar, Stavros Kiliaridis, Karl-Friedrich Krey, Robin Bülow, Henry Völzke, Thomas Kocher, Amro Daboul
OBJECTIVES: Evidence on possible associations between facial morphology, attachment loss and gingival recession is lacking. We analyzed whether the facial type, which can be described by the ratio of facial width and length (facial index), is related to periodontal loss of attachment, hypothesizing that a broad face might be associated with less gingival recession (GR) and less clinical attachment loss (CAL) than a long face. MATERIALS AND METHODS: Data from the 11-years follow-up of the population-based Study of Health in Pomerania were used...
December 8, 2016: Journal of Clinical Periodontology
https://www.readbyqxmd.com/read/27930813/free-gingival-grafts-for-implants-exhibiting-lack-of-keratinized-mucosa-a-prospective-controlled-randomized-clinical-study
#20
Se-Lim Oh, Radi M Masri, David A Williams, Chao Ji, Elaine Romberg
INTRODUCTION: To evaluate clinical and radiographic outcomes following free gingival grafts (FGGs) around implants with limited keratinized mucosa (KM) during 18 months follow-up compared to oral prophylaxis without augmentation. MATERIALS AND METHODS: This prospective controlled randomized blind clinical study investigated 41 implants displaying lack of KM in 28 subjects. After baseline examination, fourteen subjects in the experimental group received FGGs followed by oral prophylaxis and fourteen subjects in the control group received oral prophylaxis only...
December 8, 2016: Journal of Clinical Periodontology
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