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Journal of Clinical Periodontology

Kelly McGowan, Troy McGowan, Saso Ivanovski
AIM: This systematic review aimed to determine the optimum dose and duration of amoxicillin-plus-metronidazole prescribed as an adjunct to non-surgical treatment of periodontitis. METHODS: Electronic searching identified 376 records, of which 18 were eligible blinded, randomized placebo-controlled trials. The primary outcomes assessed were periodontal pocket depth and clinical attachment level at 3-months, and secondary outcomes were adverse events and compliance...
October 13, 2017: Journal of Clinical Periodontology
Ricardo Teles, Kevin Moss, John S Preisser, Robert Genco, William V Giannobile, Patricia Corby, Nathalia Garcia, Heather Jared, Gay Torresyap, Elida Salazar, Julie Moya, Cynthia Howard, Robert Schifferle, Karen L Falkner, Jane Gillespie, Debra Dixon, MaryAnn Cugini
The goal of the present longitudinal cohort study was to examine patterns of periodontal disease progression at progressing sites and subjects defined based on linear mixed models (LMM) of clinical attachment loss (CAL) METHODS: 113 periodontally healthy and 302 periodontitis subjects had their CAL calculated bi-monthly for 12 months. LMMs were fitted for each site and the predicted CAL levels used to categorize their progression state. Participants were grouped based on the number of progressing sites into unchanged, transitional and active subjects...
October 6, 2017: Journal of Clinical Periodontology
Michitsuna Katafuchi, Bradley F Weinstein, Brian G Leroux, Yen-Wei Chen, Diane M Daubert
AIM: The purpose of this study was to determine if restoration emergence angle was associated with peri-implantitis. MATERIALS AND METHODS: A data set consisting of 96 patients with 225 implants (mean follow-up: 10.9 years) was utilized. Implants were divided into bone level and tissue level groups and radiographs were analyzed to determine the restoration emergence angles, as well as restoration profiles (convex or concave). Peri-implantitis was diagnosed based on probing depth and radiographic bone loss...
October 6, 2017: Journal of Clinical Periodontology
Masanori Iwasaki, George W Taylor, Shuji Awano, Akihiro Yoshida, Shota Kataoka, Toshihiro Ansai, Hidetoshi Nakamura
AIM: To evaluate the association between periodontal disease and pneumonia mortality in hemodialysis patients. MATERIALS AND METHODS: This prospective cohort study included 211 patients (mean age, 64.4 years) undergoing hemodialysis at a single medical center. The patients underwent a baseline clinical dental examination in 2008 and were then followed up until July 2015. Periodontal disease was defined as the presence of clinical attachment loss of ≥4 mm in ≥30% of the probed sites...
October 6, 2017: Journal of Clinical Periodontology
Yoshinori Shirakata, Richard J Miron, Yukiya Shinohara, Toshiaki Nakamura, Kotaro Sena, Naoto Horai, Dieter D Bosshardt, Kazuyuki Noguchi, Anton Sculean
AIM: To investigate the effect of a novel enamel matrix derivative formulation (EMD-liquid or Osteogain) combined with an absorbable collagen sponge (ACS) on periodontal wound healing in intrabony defects in monkeys. MATERIALS AND METHODS: Chronic 2-wall intrabony defects were created at the distal aspect of 8 teeth in 3 monkeys (Macaca fascicularis). The 24 defects were randomly assigned to one of the following treatments: (1) Open flap debridement (OFD) + ACS alone, (2) OFD + Emdogain + ACS (Emdogain/ACS), (3) OFD + Osteogain + ACS (Osteogain/ACS), or (4) OFD alone...
October 1, 2017: Journal of Clinical Periodontology
Henrique Rinaldi Matheus, Edilson Ervolino, Paula Lazilha Faleiros, Vivian Cristina Noronha Novaes, Leticia Helena Theodoro, Valdir Gouveia Garcia, Juliano Milanezi de Almeida
The purpose of this study in animals was to evaluate the peri-implant bone repair against systemic administration of the antineoplastic agent MATERIAL AND METHODS: Were used 84 male rats (Rattus norvegicus albinus - Wistar), divided in two groups, Cisplatin (CIS) and saline solution (SS). The titanium implants were inserted into the right tibia at day 0 in all animals from both groups. Group SS: Received SS via intraperitoneal at 15 and 17 days postoperatively. Group CIS: Received 5mg/kg and 2.5mg/kg of cisplatin via intraperitoneal, at 15 and 17 days, postoperatively and respectively...
October 1, 2017: Journal of Clinical Periodontology
Falk Schwendicke, Christof E Dörfer, Toni Meier
AIM: We aimed to quantify the smoking-attributable burden of periodontal disease (PD). METHODS: The association between smoking and PD was evaluated. Population-, smoking- and PD-data from the Global Burden of Disease Study were used and the burden in different sex- and age-groups in 186 countries in 2015 calculated, adjusted for PD-prevalence and numbers of cigarettes smoked. No adjustment was performed in a sensitivity analysis. RESULTS: The global smoking-attributable burden was 251,160 disability-adjusted life years (DALYs; 95% uncertainty interval: 190,721-324,241; sensitivity analysis: 344,041 DALYs), or 38...
October 1, 2017: Journal of Clinical Periodontology
Stefan Renvert, Christel Lindahl, G Rutger Persson
AIM: to determine the prevalence and development of peri-implant mucositis and peri-implantitis and to assess risk factors over time. MATERIALS AND METHODS: The study is a longitudinal case series assessing the occurrence and diagnosis of peri-implant mucositis and peri-implantitis. RESULTS: 218/294 patients who had received dental implants between 1988-1992 were examined between 2000-2002 (exam II; 9-14 years after the first exam). At exam III (20-26 years after exam I, on average 23...
September 29, 2017: Journal of Clinical Periodontology
Elise G Zuiderveld, Henny J A Meijer, Laurens den Hartog, Arjan Vissink, Gerry M Raghoebar
AIM: To assess the effect of connective tissue grafting on the mid-buccal mucosal level (MBML) of immediately placed and provisionalized single implants in the maxillofacial esthetic zone. MATERIALS AND METHODS: Sixty patients with a failing tooth were provided with an immediately placed and provisionalized implant. During implant placement, patients randomly received either a connective tissue graft from the maxillary tuberosity (n=30, test group) or no graft (n=30, control group)...
September 23, 2017: Journal of Clinical Periodontology
Yago Leira, Pablo Ameijeira, Clara Domínguez, Rogelio Leira, Juan Blanco
AIM: To evaluate the prevalence of periodontitis (CP) and its contribution to serum leptin levels in chronic migraine (CM). MATERIAL AND METHODS: In this case-control study, we included 150 subjects divided into healthy controls (n=58) and CM patients (n=92). Demographic, neurological, clinical data as well as full-mouth periodontal records were obtained. Serum leptin levels were measured by ELISA technique. RESULTS: Both the prevalence of CP and mean serum leptin levels were significantly higher in patients with CM in comparison to controls (57...
September 18, 2017: Journal of Clinical Periodontology
Sarah Hiyari, Ryan Wong, Aline Yaghsezian, Azadi Naghibi, Sotirios Tetradis, Paulo M Camargo, Flavia Q Pirih
AIM: Peri-implantitis (PI), inflammation around dental implants, shares characteristics with periodontitis (PD). However, PI is more difficult to control, treat, and detailed pathophysiology is unclear. We aimed to compare PI and PD progression utilizing a murine model. MATERIALS AND METHODS: Four-week-old male C57BL/6J mice had their left maxillary molars extracted. Implants were placed in healed extraction sockets and osseointegrated. Ligatures were tied around the implant and second molar...
September 16, 2017: Journal of Clinical Periodontology
Falk Schwendicke, Anne Sophie Biffar, Christian Graetz
AIM: This study assessed the long-term annual costs for treating aggressive periodontitis (AgP) patients. METHODS: A cohort of compliant AgP patients was retrospectively evaluated. Costs for active periodontal therapy (APT, including scaling and root planning, open flap debridement, root resections, but not pocket-elimination or regenerative surgery) and supportive periodontal therapy (SPT, including also costs for restorative, endodontic, prosthetic and surgical treatments) were estimated from a mixed payer-perspective in Germany...
September 14, 2017: Journal of Clinical Periodontology
Olivier Carcuac, Jan Derks, Ingemar Abrahamsson, Jan L Wennström, Max Petzold, Tord Berglundh
OBJECTIVES: This study reports on the 3-year follow-up of patients enrolled in a randomized controlled clinical trial on surgical treatment of advanced peri-implantitis. MATERIAL & METHODS: 100 patients with advanced peri-implantitis were randomly assigned to one of four treatment groups. Surgical therapy aiming at pocket elimination was performed and, in three test groups, supplemented by either systemic antibiotics, use of an antiseptic agent for implant surface decontamination or both...
September 13, 2017: Journal of Clinical Periodontology
Ralf-Joachim Kohal, Benedikt Christopher Spies, Annalena Bauer, Frank Butz
AIM: This 3-year report of a prospective long-term cohort investigation aimed to evaluate the clinical and radiographic outcomes of a one-piece zirconia oral implant for single tooth replacement. MATERIALS AND METHODS: 65 patients received a 1-stage implant surgery with immediate temporization. Standardized radiographs were taken at implant insertion, after 1 year, and after 3 years to monitor peri-implant bone levels. A univariate analysis of the association of different baseline parameters on marginal bone loss from implant insertion to 36 months was performed...
September 13, 2017: Journal of Clinical Periodontology
Odd Carsten Koldsland, Johan Caspar Wohlfahrt, Anne Merete Aass
AIM: To evaluate the clinical and radiographic short-term (6 months) effect of surgical treatment of peri-implantitis, and to identify prognostic indicators affecting the outcome using a multilevel statistical model. MATERIAL & METHODS: A total of 143 implants (45 patients) with a diagnosis of progressive peri-implantitis (progressive bone loss ≥2.0mm and BoP/suppuration) received surgical treatment. Clinical and radiographic parameters were assessed 6 months post-operatively...
September 13, 2017: Journal of Clinical Periodontology
Pedro Martinez-Canut, Jaime Alcaraz, Jaime Alcaraz, Pablo Alvarez-Novoa, Carmen Alvarez-Novoa, Ana Marcos, Blas Noguerol, Fernando Noguerol, Ion Zabalegui
AIMS: To develop a prediction model for tooth loss due to periodontal disease (TLPD) in patients following periodontal maintenance (PM), and assess its performance using a multicentre approach. MATERIAL AND METHODS: A multilevel analysis of eleven predictors of TLPD in 500 patients following PM was carried out to calculate the probability of TLPD. This algorithm was applied to three different TLPD samples (369 teeth) gathered retrospectively by nine periodontist, associating several intervals of probability with the corresponding survival rates, based on significant differences in the mean survival rates...
September 4, 2017: Journal of Clinical Periodontology
P Juliana Pérez-Chaparro, John Anthony McCulloch, Elsa Masae Mamizuka, Aline da Costa Lima Moraes, Marcelo Faveri, Luciene Cristina Figueiredo, Poliana Mendes Duarte, Magda Feres
To perform a thorough characterization of the subgingival microbiota of shallow, moderate and deep sites in subjects with chronic periodontitis (ChP) MATERIAL AND METHODS: Subgingival samples were collected from subjects with ChP (n=3/category of probing depth: ≤3, 4-6 and ≥7 mm) and periodontal health (PH). Samples were individually analyzed by high-throughput sequencing and the sequences were analyzed using mothur and R packages RESULTS: Nine subjects with ChP and seven with PH were included and 101 samples were evaluated...
September 4, 2017: Journal of Clinical Periodontology
Mizuki Saito, Yoshihiro Shimazaki, Toshiya Nonoyama, Yasushi Tadokoro
AIM: There is an association between type 2 diabetes mellitus (T2DM) and periodontitis. We examined the association between the dental visit status and diabetes status in the Japanese elderly population. MATERIALS AND METHODS: In total, 14,551 participants, aged 75 or 80 years, who underwent systemic health examinations were analyzed. Three independent variables of dental visit status were investigated according to dental claims data, including whether dental treatment was received, type of dental treatment (no visit, periodontal treatment, or other dental treatment), and number of days of periodontal treatment (0, 1-4, or ≥5 days)...
August 23, 2017: Journal of Clinical Periodontology
Yi Wang, Hin Nam Liu, Zhe Zhen, Kai Hang Yiu, Hung Fat Tse, George Pelekos, Maurizio Tonetti, Lijian Jin
BACKGROUND: Periodontitis is closely linked with type 2 diabetes mellitus (T2DM) and endothelial dysfunction. This study investigated the effects of periodontal treatment on immuno-inflammatory gene expression of endothelial progenitor cells (EPCs) in diabetic patients. METHODS: Eighteen T2DM patients with moderate to severe chronic periodontitis were randomly assigned to the Treatment group with oral hygiene instruction (OHI), scaling and root debridement (n=11), and Control group (n=7) with OHI alone...
August 23, 2017: Journal of Clinical Periodontology
Ines Kapferer-Seebacher, Pernilla Lundberg, Franziska Malfait, Johannes Zschocke
AIM: Ehlers-Danlos syndromes (EDS) are a group of inherited connective tissue disorders, characterized by joint hypermobility, skin hyperextensibility, and tissue fragility. Periodontal EDS (pEDS) is a specific EDS subtype caused by heterozygous mutations in complement 1 subunit genes C1R and C1S, with early severe periodontitis as predominant clinical feature. We aimed to systematically assess the spectrum of periodontal abnormalities in all EDS subtypes. MATERIALS AND METHODS: An electronic and manual search was conducted in three databases (Medline, LIVIVO, CENTRAL)...
August 23, 2017: Journal of Clinical Periodontology
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