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Journal of Clinical Periodontology

M L Jourdain, L Pierrard, L Kanagaratnam, F Velard, J Sergheraert, B Lefèvre, S C Gangloff, J Braux
AIM: Antimicrobial peptides (AMPs) are one of the most active components of innate immunity and have characteristics that could place them at the heart of the pathogenesis of periodontal disease. This study investigated differences in the expression of AMP coding genes obtained using a simple harvesting technique, gingival smear, between two groups of patients: chronic periodontitis subjects vs healthy ones. MATERIALS AND METHODS: Twenty-three patients were enrolled in two groups: 12 were diagnosed with moderate or severe generalized chronic periodontitis and 11 were diagnosed as clinically healthy...
February 15, 2018: Journal of Clinical Periodontology
Akihiko Tanaka, Kenji Takeuchi, Michiko Furuta, Toru Takeshita, Shino Suma, Takashi Shinagawa, Yoshihiro Shimazaki, Yoshihisa Yamashita
AIM: To examine the effect of tooth brushing on the development of metabolic syndrome, including assessment of periodontal status, in middle-aged adults. METHODS: This 5-year follow-up retrospective study was performed in 3722 participants (2897 males and 825 females) aged 35-64 years who underwent both medical check-ups and dental examinations. Metabolic components included obesity, elevated triglycerides, blood pressure, fasting glucose, and reduced high-density lipoprotein...
February 8, 2018: Journal of Clinical Periodontology
Simone Cortellini, Ana B Castro, Andy Temmerman, Jeroen Vandessel, Nelson Pinto, Reinhilde Jacobs, Marc Quirynen
AIM: The objective of this proof-of-concept study was to investigate the effects of a new GBR technique with a tissue engineering approach. MATERIAL AND METHODS: This single cohort observational study evaluated the outcome of the L-PRF block for horizontal bone augmentation in the maxilla. The L-PRF block is prepared by mixing a particulated biomaterial with chopped L-PRF membranes at a 50:50 ratio and adding Liquid Fibrinogen to glue all together. Horizontal augmentation was assessed linearly and volumetrically immediately after surgery and 5-8 months later by matching consecutive CBCTs...
February 8, 2018: Journal of Clinical Periodontology
L Jauhiainen, A L Suominen, S Männistö, M Knuuttila, P Ylöstalo
AIM: To examine whether a healthy diet based on nutrient recommendations is associated with periodontal condition in smokers. MATERIAL AND METHODS: Daily smokers from the cross-sectional Health 2000 Survey in Finland, analyzed in two age groups (30-49 and 50-79 years, n= 704 and 267) and according to the level of oral hygiene. Periodontal condition was measured as the number of sextants with gingival bleeding and teeth with ≥ 4 mm deepened periodontal pockets...
February 8, 2018: Journal of Clinical Periodontology
M Pietiäinen, K A E Kopra, J Vuorenkoski, A Salminen, S Paju, P Mäntylä, K Buhlin, J M Liljestrand, M S Nieminen, J Sinisalo, K Hyvärinen, P J Pussinen
AIM: We investigated the association between the Aggregatibacter actinomycetemcomitans serotypes, periodontal status, and coronary artery disease (CAD). MATERIALS AND METHODS: The study population included 497 patients who underwent coronary angiography, and clinical oral examination. Quantitative polymerase chain reaction assays were designed to identify the serotypes from saliva samples. RESULTS: A. actinomycetemcomitans serotype frequencies were: serotype "c" 35...
January 31, 2018: Journal of Clinical Periodontology
Brenda Heaton, Praveen Sharma, Raul I Garcia, Thomas Dietrich
AIM: To evaluate the assumptions underlying the use of partial-mouth recording (PMR) protocols and the associated mechanisms of potential misclassification of periodontal disease. METHODS: Using data from 640 participants in the VA Dental Longitudinal Study, we compared tooth-specific and site-specific clinical measures, and calculated sensitivity and specificity of different PMR protocols by applying the CDC-AAP definitions for periodontitis as the full-mouth reference standard...
January 31, 2018: Journal of Clinical Periodontology
Stefanie Samietz, Clemens Jürgens, Till Ittermann, Birte Holtfreter, Christiane Pink, Sabine Schipf, Reiner Biffar, Henry Völzke, Thomas Kocher, Frank Tost
AIM: To investigate the relation between oral health status and microcirculation we analyzed the association between periodontitis and number of teeth with retinal vessel diameters. METHODS: We analyzed data from 4420 subjects from the Study-of-Health-in-Pomerania-TREND (SHIP-TREND). All subjects (3183 for number of teeth, 3013 for mean probing depth, 2894 for mean attachment level) underwent nonmydriatic funduscopy and dental examination. We measured central retinal arteriolar (CRAE), venular (CRVE) vessel diameters and calculated arterio-venous-ratio (AVR) from static-vessel-analysis...
January 31, 2018: Journal of Clinical Periodontology
Jung-Hoo Lee, Yoo-Jin Shin, Jong-Ho Lee, Hyun-Duck Kim
AIM: Toothbrushing (TB), dental flossing (DF) and inter-dental brushing (IDB) are regarded as fundamental self-care methods for periodontal health. Few evidences on its effectiveness on periodontal health are available. Hence, this study aimed to evaluate the association of TB, DF, IDB and interaction effect with periodontal health. MATERIALS AND METHODS: The nationally representative 4,766 Korean adults aged 19 years and older were cross-sectionally surveyed in 2010 and 2012...
January 25, 2018: Journal of Clinical Periodontology
Stijn Vervaeke, Carine Matthys, Rima Nassar, Veronique Christiaens, Jan Cosyn, Hugo De Bruyn
AIM: To evaluate the effect of soft tissue thickness on bone remodeling and to investigate if implant surface exposure can be avoided by adapting the vertical implant position in relation to the soft tissue thickness. MATERIALS&METHODS: Twenty-five patients received two non-splinted implants supporting an overdenture in the mandible. Soft tissue thickness was measured using bone sounding and ultrasonically. One implant was installed equicrestally(control) and the vertical position of the second implant was adapted to the site-specific soft tissue thickness(test)...
January 23, 2018: Journal of Clinical Periodontology
Tim Hilgenfeld, Thorsten Kästel, Alexander Heil, Peter Rammelsberg, Sabine Heiland, Martin Bendszus, Franz Sebastian Schwindling
AIM: To evaluate whether high-resolution, non-contrast-enhanced dental MRI can be used for accurate determination of palatal-masticatory-mucosa-thickness (PMMT) and to locate the greater palatal artery (GPA). MATERIALS AND METHODS: In five volunteers (4 males, 1 female; mean age 30.2±0.4 years) two independent raters measured PMMT by use of dental MRI in 180 positions. For comparison, clinical bone sounding was performed. The GPA was identified in time-of-flight (TOF) angiography and MSVAT-SPACE-prototype sequence...
January 15, 2018: Journal of Clinical Periodontology
Ernest Rojo, Giorgio Stroppa, Ignacio Sanz-Martin, Oscar Gonzalez-Martín, Antonio Santos Alemany, José Nart
AIM: To compare the soft tissue volume gain (VG) around single tooth implants with subepithelial connective tissue graft (SCTG) from either the lateral palate (LP) or from the tuberosity area (TA). METHODS: 32 patients with 36 implants with buccal volume deficiencies were randomly assigned to receive SCTG from LP (control group/CG) or TA (test group/TG). Clinical parameters were recorded and volume gain was evaluated by STL image superimposition of 2 intraoral scans (baseline/BL and 3 months after surgery/FU-3)...
January 15, 2018: Journal of Clinical Periodontology
Frank Schwarz, Jürgen Becker, Sara Civale, Didem Hazar, Theresa Iglhaut, Gerhard Iglhaut
OBJECTIVES: To assess the onset, progression and resolution of experimentally induced peri-implant mucositis lesions at abutments with different microstructures in humans. MATERIAL & METHODS: In a randomized, controlled, interventional two-centre study, a total of 28 patients had received 28 target implants and were randomly allocated to either partially microgrooved (test) or machined (control) healing abutments. The study was accomplished in three phases, including a wound healing period (WH) following implant placement (12 weeks), a plaque exposure phase (EP-21 days) and a resolution phase (RP-16 weeks)...
January 13, 2018: Journal of Clinical Periodontology
Samuel Huber, Marco Zeltner, Christoph H F Hämmerle, Ronald E Jung, Daniel S Thoma
AIM: To assess peri-implant soft tissue dimensions at implant sites, previously augmented with a collagen matrix (VCMX) or an autogenous subepithelial connective tissue graft (SCTG), between crown insertion and 1 year. METHODS: Twenty patients with single-tooth implants received soft tissue augmentation prior to abutment connection randomly using VCMX or SCTG. Following abutment connection 3 months later, final reconstructions were fabricated and inserted (baseline)...
December 31, 2017: Journal of Clinical Periodontology
J Nuñez, N Sanchez, F Vignoletti, I Sanz-Martin, R Caffesse, S Santamaria, J A Garcia-Sanz, M Sanz
AIM: The objective of this in-vivo experimental study to evaluate the regenerative potential of a cell therapy combining allogenic periodontal ligament derived cells with in a xenogeneic bone substitute in a similar experimental model. METHODS: In 9 beagle dogs, critical-size 6 mm supra-alveolar periodontal defects were created around the PIII and PIV. The resulting supra-alveolar defects were randomly treated with either 1.4 x 106 allogenic canine periodontal ligament-derived cells seeded on de-proteinized bovine bone mineral with 10% collagen (DBBM-C) (test group), or DBBM-C without cells (control group)...
December 29, 2017: Journal of Clinical Periodontology
Phoebus N Madianos, Panagiotis A Koromantzos
AIM: To provide an update of the systematic review by Engebretson and Kocher J Clin Periodontol. 2013 Apr;40 Suppl 14:S153 on the effect of periodontal therapy on glycaemic control of people with diabetes. METHODS: PubMed Literature search restricted to meta-analyses published from 2013 to the present was conducted. The search resulted in seven meta-analyses of RCTs. RESULTS: Reduction in HbA1c at 3-4 months was reported in all reviews for the treatment group ranging from -0...
December 26, 2017: Journal of Clinical Periodontology
Guojing Liu, Qingxian Luan, Feng Chen, Zhibin Chen, Qian Zhang, Xiaoqian Yu
AIM: To investigate the shift in the subgingival microbiota under scaling and root planing (SRP) in generalized aggressive periodontitis (GAgP) patients. MATERIALS AND METHODS: After undergoing supragingival scaling, twelve individuals with GAgP were enrolled in this longitudinal study. Full-mouth SRP was accomplished in 3 weeks and re-evaluated 6 weeks later. Pooled subgingival samples (posterior-mesial, posterior-buccal, anterior-mesial, and anterior-buccal) were obtained from each patient before SRP (pre-treatment group) and at the time of re-evaluation (post-treatment group)...
December 21, 2017: Journal of Clinical Periodontology
Elastria Widita, Akihiro Yoshihara, Lisdrianto Hanindriyo, Hideo Miyazaki
AIMS: An association between periodontal disease and liver enzymes has been reported previously. This study examined the relationship between clinical periodontal parameters and changes in liver enzymes levels in 265 non-institutionalized Japanese elderly aged 72 years over eight years. MATERIALS AND METHODS: Periodontal parameters were measured by using the number of sites with probing pocket depth (PPD) ≥ 6 mm and clinical attachment level (CAL) ≥ 6 mm. Changes in liver enzymes (alanine transaminase [ALT] and aspartate transaminase [AST]) was grouped based on any elevation of concentrations...
December 19, 2017: Journal of Clinical Periodontology
Nadja Naenni, Stefan P Bienz, Fernando Muñoz, Christoph H F Hämmerle, Ronald E Jung, Daniel S Thoma
AIM: To assess volumetric and linear changes following ridge preservation (RP) or spontaneous healing plus early implant placement with or without simultaneous guided bone regeneration (GBR). MATERIALS AND METHODS: In eight adult beagle dogs, the mesial roots of the mandibular P3, P4 and M1 were extracted. Sites were randomized to either ridge preservation (RP) or spontaneous healing (SH). Four weeks later dental implants were placed either with (RP2) or without removing non-integrated DBBM (RP1)...
December 19, 2017: Journal of Clinical Periodontology
Elisabet Mauri-Obradors, Alexandra Merlos, Albert Estrugo-Devesa, Enric Jané-Salas, José López-López, Miguel Viñas
BACKGROUND: Periodontitis and diabetes are highly prevalent conditions whose association has long been recognized. OBJECTIVE: To evaluate the effect of nonsurgical periodontal treatment on serum HbA1c (hemoglobin A1c or glycated hemoglobin) levels in patients with type 2 diabetes. RESEARCH DESIGN AND METHODS: This was a 6-month, single-masked, randomized clinical trial based on 90 patients (HbA1c: 7.7% (61 mmol/mol) ± 1.13%) who were randomly assigned to either the treatment group (oral hygiene instructions + scaling and root planning using ultrasound and Gracey curettes) or the control group (oral hygiene instructions + supragingival removal of plaque and calculus using ultrasound)...
December 19, 2017: Journal of Clinical Periodontology
Fabian Cieplik, Laura Tabenski, Karl-Anton Hiller, Gottfried Schmalz, Wolfgang Buchalla, Michael Christgau
AIM: To investigate the clinical long-term outcomes 13 years following guided tissue regeneration (GTR) in deep intrabony defects with and without additional application of autogenous platelet concentrate (APC). METHODS: In 25 patients, two deep contra-lateral intrabony defects were treated according to GTR using ß-TCP and bio-resorbable membranes. In test defects, APC was applied additionally. After 13 years, clinical healing results were assessed and compared to results at baseline and after 1 year...
December 15, 2017: Journal of Clinical Periodontology
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