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Journal of Dentistry

Mathilde C Peters, Aubrey R Hopkins, Qingzhao Yu
OBJECTIVES: Micro-invasive resin-infiltration has shown to inhibit lesion progression of proximal non-cavitated carious lesions, suggesting an alternative to early operative treatment. This split-mouth, randomized placebo-controlled clinical trial evaluated the effects of proximal lesion infiltration supplementary to standard-of-care management in high caries risk (HCR)-patients. METHODS: Forty-two HCR-subjects with two similar interproximal posterior lesions received professional HCR-regimen including repeated F-varnish applications...
September 15, 2018: Journal of Dentistry
Murali Srinivasan, Martin Schimmel, Manuel Naharro, Ciaran O' Neill, Gerald McKenna, Frauke Müller
ObjectiveThis study compared the clinical time spent and the costs incurred whilstconstructing complete dentures (CDs) using a two-visit digital-denture protocol (DDP) with the conventional complete denture protocol (CCDP), in a university setting.Methods Twelve undergraduate final-year dental students utilized both the DDP and the CCDP to construct two sets of CDs for patients requiring either an upper CD opposing a partial natural dentition restored using a partial removable prosthesis [Group#1: students: n = 6, upper CD: n = 12 (6-DDP +6-CCDP)] or both upper and lower CDs [Group#2: students: n = 6, upper and lower CDs: n = 24 (12-DDP + 12-CCDP)]...
September 10, 2018: Journal of Dentistry
Clovis Mariano Faggion, Robert S Ware, Nikolaos Bakas, Jason Wasiak
OBJECTIVES: To comprehensively report on the characteristics of retracted publications in the field of dentistry. METHODS: We searched MEDLINE (via PubMed), PubMed Central, Web of Science and Google Scholar databases for dental retracted articles from database inception to 02 July 2018. In addition, we scanned the search engine, Google Scholar, and the website, Retraction Watch (, for retracted dental studies. Two researchers independently screened titles, abstracts and full text of search results...
September 8, 2018: Journal of Dentistry
Bruna Maria de Carvalho Martins, Emmanuel João Nogueira Leal da Silva, Daniele Masterson Tavares Pereira Ferreira, Kátia Rodrigues Reis, Tatiana Kelly da Silva Fidalgo
OBJECTIVES: This systematic review aimed to verify if there is difference in the longevity of minimally invasive techniques compared to the complete replacement for the treatment of defective direct restorations in permanent teeth. DATA: The data included randomized controlled clinical trials comparing the clinical performance of defective dental restorations treated by a complete replacement technique or minimally invasive techniques on permanent teeth. Evaluation of the risk of bias was performed using the Cochrane Collaboration common scheme for bias and the evidence was qualified using the GRADE tool...
September 3, 2018: Journal of Dentistry
Christopher D Lynch, Jessica L Roberts, Ali Al-Shehri, Paul J Milward, Alastair J Sloan
AIM: Based on histological studies from the 1960s, it is recommended that dental pulp temperature increases should not exceed 5.5 °C. However, no contemporary reliable models exist to explore the effects of heat on living dental pulp. The aim of this project was to develop a clinically valid model for studying temperature increases caused by three commonly-used light curing units (LCUs). METHODS: Temperature increases caused by LCUs at varying exposure times and via various thicknesses of dentine were recorded using traditional approaches and an ex-vivo tooth slice model...
August 31, 2018: Journal of Dentistry
Falk Schwendicke, Joachim Krois, Ulrich Schiffner, Wolfgang Micheelis, Rainer A Jordan
INTRODUCTION: We assessed time trends in root caries experience, i.e. the sum of filled and carious root surfaces (FRS, CRS), and evaluated risk indicators of FRS/CRS in Germany. METHODS: FRS and CRS from repeated waves (1997, 2005, 2014) of the nationally-representative German Oral Health Studies were analyzed in 35-44- and 65-74-year-olds (adults/younger seniors; n = 4388). Weighted means were interpolated cross-sectionally across age groups by fitting piecewise-cubic spline-curves, and population-level FRS and CRS calculated...
August 27, 2018: Journal of Dentistry
Faisal D Al-Qarni, Franklin Tay, Michael D Weir, Mary A S Melo, Jirun Sun, Thomas W Oates, Xianju Xie, Hockin H K Xu
OBJECTIVES: The objectives were to develop a calcium (Ca) and phosphate (P) ion-rechargeable and protein-repellent adhesive containing nanoparticles of amorphous calcium phosphate (NACP) and 2-methacryloyloxyethyl phosphorylcholine (MPC), and investigate the MPC effects on ion recharge and re-releases for the first time. METHODS: Pyromellitic glycerol dimethacrylate and ethoxylated bisphenol-A dimethacrylate were used to fabricate adhesive PEHB. Six adhesives were tested: (1) Scotchbond (SBMP); (2) PEHB, (3) PEHB + 20%NACP; (4) PEHB + 30%NACP; (5) PEHB + 20%NACP+3%MPC; (6) PEHB + 30%NACP+3%MPC...
August 25, 2018: Journal of Dentistry
Huiyi Yan, Shilei Wang, Lin Han, Wenan Peng, Luyao Yi, Rui Guo, Siying Liu, Hongye Yang, Cui Huang
OBJECTIVES: This work aims to explore the feasibility of chlorhexidine-encapsulated mesoporous silica (CHX@pMSN) as a modifier of a commercial dental adhesive via the evaluation of physicochemical properties and antibacterial capabilities of adhesive-dentin interface. METHODS: Therapeutic adhesives were developed in the present study by incorporating CHX@pMSN into a commercial adhesive at four mass fractions (0, 1, 5 and 10 wt.%). The antibacterial capability on Streptococcus mutans (S...
August 25, 2018: Journal of Dentistry
Masatoshi Ando, Margherita Fontana, George J Eckert, Rodrigo A Arthur, Hui Zhang, Domenick T Zero
OBJECTIVES: Evaluate the ability of objectively measured specular reflection, roughness, and fluorescence change during dehydration to assess caries lesion activity. METHODS: One hundred ninety-five ground/polished 3 × 3 × 2 mm sound human enamel specimens were divided into three groups and demineralized using a multispecies microbial caries model for 3, 6, or 9 days; and then remineralized with 1100 ppm-F as NaF solution for 10 days using a pH-cyclic model...
August 19, 2018: Journal of Dentistry
Gregory Celine, Vanessa Cho, Alexandr Kogan, Robert Anthonappa, Nigel King
OBJECTIVES: To determine, using eye-tracking technology, what children notice the most when they look at the dentist. METHODS: A total of 41 children viewed 10 images of dentists of different genders and ethnicities, and wearing different attires, on a computer screen. Due to calibration issues with the eye tracking equipment, data from one child was excluded thus resulting in a final sample of 40 children (21 females; 19 males). Participants were aged 4-12 years...
August 13, 2018: Journal of Dentistry
Ollie Y Yu, Irene S Zhao, May L Mei, Edward C M Lo, C H Chu
OBJECTIVES: To investigate the remineralising effect and bacterial growth inhibition of 38% silver diamine fluoride (SDF) solution and 5% sodium fluoride (NaF) varnish on artificial dentine caries lesions. METHODS: Demineralised dentine blocks were treated with SDF + NaF (Group 1), SDF (Group 2), NaF (Group 3) and water (Group 4) and subjected to a Streptococcus mutans biofilm challenge. Lesion depth, precipitates' characteristics and matrix (collagen)-to-mineral ratio were evaluated by micro-computer tomography (micro-CT), X-ray diffraction (XRD) and Fourier transform infrared spectroscopy (FTIR), respectively...
August 13, 2018: Journal of Dentistry
Peiyan Shen, Glenn D Walker, Yi Yuan, Coralie Reynolds, David P Stanton, James R Fernando, Eric C Reynolds
OBJECTIVES: To compare remineralization of enamel subsurface lesions by fluoride dentifrices with added calcium in a double-blind, randomized, cross-over, in situ study. METHODS: Human enamel with subsurface lesions were prepared and inserted into intra-oral appliances worn by volunteers. A slurry (1 g toothpaste/4 ml H2 O) was rinsed for 60 s, 4 times per day for 14 days. Seven toothpastes were tested: (i) 1450 ppm F (NaF), (ii) 5000 ppm F (NaF), (iii) 1450 ppm F (MFP) with calcium sodium phosphosilicate (CSP), (iv) 1450 ppm F (MFP) with CaCO3 /Arg, (v) 1150 ppm F (SnF2 ) with amorphous calcium phosphate (ACP), (vi) 1100 ppm F (NaF) with casein phosphopeptide-amorphous calcium phosphate (CPP-ACP) and (vii) 5000 ppm F (NaF) with functionalized tri-calcium phosphate (TCP)...
August 9, 2018: Journal of Dentistry
Barbara Cvikl, Adrian Lussi, Thiago Saads Carvalho, Andreas Moritz, Reinhard Gruber
OBJECTIVES: Matrix metalloproteinases (MMPs) in dentin and saliva can degrade collagen. Divalent metals are known inhibitors of MMPs, but stannous - such as in the form of stannous chloride (SnCl2 ) or stannous fluoride (SnF2 ) - is yet to be tested for a possible inhibitory effect. In this study, we tested the inhibitory effect on the proteolytic activity of MMP-2 and MMP-9. METHODS: Sodium chloride (NaCl), sodium fluoride (NaF), and chlorhexidine (CHX) were used as controls...
August 3, 2018: Journal of Dentistry
Xue Cai, Xiao-Yan Wang, Filippo Santarcangelo, G John Schoeffel, Brian E Bergeron, Franklin R Tay, Li-Na Niu
INTRODUCTION: The present study examined the effects of irrigant flow rate and simulated intraosseous sinusoidal pressure on the rate of NaOCl extrusion from the apical terminus of a faux root canal. METHODS: An extrusion setup was designed to enable irrigant extrusion to be opposed by 30 mm Hg simulated intraosseous pressure. The faux canal apex was opposed by atmospheric + 30 mm Hg pressure (experimental) or atmospheric pressure only (control group). Using five irrigant delivery rates (15...
August 2, 2018: Journal of Dentistry
Chirayu Ruengrungsom, Joseph E A Palamara, Michael F Burrow
OBJECTIVES: To review the clinical performance of GIC restorations using calculated annual failure rates and qualitative descriptions based on conventional and ART techniques from two aspects: occlusal and approximal cavities in permanent or deciduous posterior teeth. SOURCES: Search strategies was undertaken of the PubMed database from January 1983 to March 2018. Additional articles were collected by hand searching. STUDY SELECTION: The following basic search terms, "(glass ionomer cement) and (clinical performance or survival or ART or atraumatic restorative or high viscosity)" with inclusion and exclusion criteria according to PRISMA flow diagram...
July 11, 2018: Journal of Dentistry
Sofia Chatzimarkou, Despina Koletsi, Katerina Kavvadia
INTRODUCTION/OBJECTIVES: This systematic review aimed to critically appraise the evidence on resin infiltration for the clinical management of proximal caries lesions in primary and permanent teeth. DATA: Search terms included resin infiltration, micro-invasive and proximal caries. Potentially eligible studies involved proximal caries lesions treated with resin infiltration. Risk of bias assessment was performed using the Cochrane risk of bias tool and the quality of evidence was assessed with GRADE...
October 2018: Journal of Dentistry
Vivian Mendes, Gustavo Oliveira Dos Santos, Vittorio Moraschini
No abstract text is available yet for this article.
October 2018: Journal of Dentistry
Ramy Emara, Karim Elhennawy, Falk Schwendicke
OBJECTIVES: The aim of this study was to evaluate the biocompatibility, odontogenic, angiogenic and inflammatory effects of commercially available calcium silicate cements (CSCs) on dental pulp cells. DATA: In vitro, animal and human in vivo studies reporting on biocompatibility, odontogenic, angiogenic and inflammatory effects of CSCs on dental pulp cells were screened using a systematic review, and a descriptive analysis performed. SOURCES: We searched Medline via PubMed, Google Scholar and Scopus, followed by hand search and cross-referencing...
October 2018: Journal of Dentistry
Jae-Hong Lee, Do-Hyung Kim, Seong-Nyum Jeong, Seong-Ho Choi
OBJECTIVES: Deep convolutional neural networks (CNNs) are a rapidly emerging new area of medical research, and have yielded impressive results in diagnosis and prediction in the fields of radiology and pathology. The aim of the current study was to evaluate the efficacy of deep CNN algorithms for detection and diagnosis of dental caries on periapical radiographs. MATERIALS AND METHODS: A total of 3000 periapical radiographic images were divided into a training and validation dataset (n = 2400 [80%]) and a test dataset (n = 600 [20%])...
October 2018: Journal of Dentistry
Domenick T Zero, Frank Lippert, Anderson T Hara, Jonathan E Creeth, Evelyn E Newby, Andrew Butler, Paul Constantin, Mary Lynn Bosma
OBJECTIVES: Data generated from three similar in situ caries crossover studies presented the opportunity to conduct a pooled analysis to investigate how dentifrice formulations with different fluoride salts and combinations at concentrations of 1400-1450 ppm F, different abrasive systems and in some cases, carbomer (Carb), affect enamel caries lesion remineralization and fluoridation. METHODS: Subjects continuously wore modified partial dentures holding two gauze-covered partially-demineralized human enamel specimens for 14 days and brushed 2×/day with their assigned dentifrice: Study 1: sodium fluoride (NaF)/Carb/silica, NaF/silica, NaF + monofluorophosphate (MFP)/chalk; Study 2: NaF/Carb/silica, NaF + MFP/dical, amine fluoride (AmF)/silica; Study 3: NaF/Carb/silica, NaF + stannous fluoride (SnF2 )/silica/hexametaphosphate (HMP)...
October 2018: Journal of Dentistry
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