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Journal of Perinatal Medicine

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https://www.readbyqxmd.com/read/30098288/prediction-of-postnatal-developmental-disabilities-using-the-antenatal-fetal-neurodevelopmental-test-kanet-assessment
#1
Toshiyuki Hata, Kenji Kanenishi, Nobuhiro Mori, Mohamed Ahmed Mostafa AboEllail, Uiko Hanaoka, Kosuke Koyano, Ikuko Kato, Takashi Kusaka
Objective To assess the usefulness of the antenatal fetal neurodevelopmental test for the prediction of postnatal developmental disabilities. Methods Fetal behavior was assessed with Kurjak's antenatal neurodevelopmental test (KANET) using four-dimensional ultrasound between 28 and 38 weeks of gestation. A score range of 0-5 was characterized as abnormal, from 6 to 9 was considered borderline, and 10-16 was normal. After birth, follow-up was conducted for at least 2 years in all fetuses. Results There were 337 normal (95...
August 11, 2018: Journal of Perinatal Medicine
https://www.readbyqxmd.com/read/30098287/somatic-development-at-birth-as-influenced-by-maternal-characteristics-an-analysis-of-the-german-perinatal-survey
#2
Dirk Manfred Olbertz, Asja Knie, Sebastian Straube, Roland Hentschel, Ekkehard Schleußner, Hans-Peter Hagenah, Jan Däbritz, Manfred Voigt
We investigated the effects of maternal age, body weight, body height, weight gain during pregnancy, smoking during pregnancy, previous live births and being a single mother on somatic development at birth. We analysed data from the German Perinatal Survey for the years 1998-2000 from eight German federal states. We had available data on 508,926 singleton pregnancies and neonates in total; for 508,893 of which we could classify the neonates as small, appropriate or large for gestational age (SGA, AGA or LGA) based on the 10th and 90th birth weight percentiles...
August 11, 2018: Journal of Perinatal Medicine
https://www.readbyqxmd.com/read/30067511/from-single-case-analysis-of-neonatal-deaths-toward-a-further-reduction-of-the-neonatal-mortality-rate
#3
André Sander, Roland Wauer
Background The infant mortality rate (IMR), a key indicator of the quality of a healthcare system, has remained at approximately 3.5‰ for the past 10 years in Germany. Generic quality indicators (QIs), as used in Germany since 2010, greatly help in ensuring such a good value but do not seem to be able to further reduce the IMR. The neonatal mortality rate (NMR) contributes to 65-70% of the IMR. We therefore propose single-case analysis of neonatal deaths as an additional method and show an efficient way to implement this approach...
August 1, 2018: Journal of Perinatal Medicine
https://www.readbyqxmd.com/read/30052523/untimely-diagnosis-of-fetomaternal-hemorrhage-what-went-wrong
#4
Isabella Piva, Piergiorgio Iannone, Danila Morano, Pantaleo Greco
Fetomaternal hemorrhage (FMH) is an obstetrical challenge. It is defined as a passage of fetal blood into the maternal circulation or vice versa, which might complicate pregnancy or delivery. Most cases of acute and chronic FMH are idiopathic in origin and involve uncomplicated near-term pregnancies. Yet, due to the lack of universal screening, heterogeneous clinical presentation and insufficient clinicians awareness, in some cases FMH may present as immediate fetal compromise or even stillbirth as the most devastating consequence...
July 27, 2018: Journal of Perinatal Medicine
https://www.readbyqxmd.com/read/30024856/comparison-of-two-different-treatments-in-depressed-pregnant-women-fetal-growth-characteristics-and-neonatal-outcomes
#5
Lisa Giardinelli, Lorenzo Lelli, Valentina Ugolini, Lisa Lazzeretti, Iuliia Burian, Giuliana Lino, Clara Lunardi, Giovanni Castellini, Valdo Ricca
Background In this pilot study, the effects of selective serotonin reuptake inhibitors (SSRIs) and psychological intervention on fetal growth characteristics and neonatal outcomes were evaluated in two different groups of women affected by prenatal depression. Methods Forty-seven pregnant women diagnosed with major depression were divided into two different treatment groups according to the severity of their depression. The first group was treated with a combination of pharmacotherapy and psychological support...
July 19, 2018: Journal of Perinatal Medicine
https://www.readbyqxmd.com/read/30020889/neonatal-ogg1-mutyh-knockout-mice-have-altered-inflammatory-gene-response-compared-to-wildtype-mice-in-the-brain-and-lung-after-hypoxia-reoxygenation
#6
Anne Gro W Rognlien, Embjørg J Wollen, Monica Atneosen-Åsegg, Rajikala Suganthan, Magnar Bjørås, Ola Didrik Saugstad
BACKGROUND: 8-Oxoguanine DNA-glycosylase 1 (OGG1) and mutY DNA glycosylase (MUTYH) are crucial in the repair of the oxidative DNA lesion 7,8-dihydro-8-oxoguanine caused by hypoxia-reoxygenation injury. Our objective was to compare the gene expression changes after hypoxia-reoxygenation in neonatal Ogg1-Mutyh double knockout mice (OM) and wildtype mice (WT), and study the gene response in OM after hyperoxic reoxygenation compared to normoxic. METHODS: Postnatal day 7 mice were subjected to 2 h of hypoxia (8% O2) followed by reoxygenation in either 60% O2 or air, and sacrificed right after completed reoxygenation (T0h) or after 72 h (T72h)...
July 18, 2018: Journal of Perinatal Medicine
https://www.readbyqxmd.com/read/29995636/association-between-increased-antenatal-vaginal-ph-and-preterm-birth-rate-a-systematic-review
#7
Marina J Weckend, Loukia M Spineli, Susanne Grylka-Baeschlin, Mechthild M Gross
Background Worldwide, 14.9 million infants (11%) are born preterm each year. Up to 40% of preterm births (PTBs) are associated with genital tract infections. The vaginal pH can reflect changes in the vaginal milieu and, if elevated, indicates an abnormal flora or infection. Objective The aim of the study was to investigate whether an increased antenatal vaginal pH >4.5 in pre-labour pregnant women is associated with an increased PTB rate <37 completed weeks gestation. Search strategy Key databases included SCOPUS, EMBASE, MEDLINE, PsycInfo and the Cochrane Central Register of Controlled Trials, complemented by hand search, up to January 2017...
July 11, 2018: Journal of Perinatal Medicine
https://www.readbyqxmd.com/read/29995635/relationship-between-intercellular-adhesion-molecule-1-and-morbidly-adherent-placenta
#8
Engin Korkmazer, Rampia Nizam, Emine Arslan, Özgür Akkurt
Objective Morbidly adherent placenta (MAP) is a clinical condition the prevalance of which is steadily increasing. It is described as the invasion of the placenta into the uterine wall through the myometrium and beyond. Several studies have shown that intercellular adhesion molecule-1 (ICAM-1) increases the invasion capability of tumor cells and placental cells. In our study, we investigated the expression of ICAM-1 in MAP cases. Study design This is a prospective case-control study. Eighty-nine patients who were diagnosed with MAP and 96 patients, without adherent placenta, as a control group were included in the study...
July 11, 2018: Journal of Perinatal Medicine
https://www.readbyqxmd.com/read/29995634/a-prospective-analysis-of-intake-and-composition-of-mother-s-own-milk-in-preterm-newborns-less-than-32-weeks-gestational-age
#9
Marta Cabrera Lafuente, M Teresa Montes Bueno, Natividad Pastrana, Cristina Segovia, Rosario Madero Jarabo, Camilia R Martin, Felix Omeñaca Teres, Miguel Sáenz de Pipaón Marcos
BACKGROUND: Mothers of preterm (PT) infants have difficulty providing adequate quantities of human milk (HM) for their babies during their hospital stay. The macronutrient content in HM changes over time, varying across and within individual mothers. Research aim: To describe the intake of mothers' own milk (MOM) and its composition according to gestational (GA) and postnatal age (PNA) in infants born <32 weeks' GA and to correlate them with neonatal weight, length and morbidities...
July 10, 2018: Journal of Perinatal Medicine
https://www.readbyqxmd.com/read/30070096/serum-biomarkers-of-neuronal-injury-in-newborns-evaluated-for-selective-head-cooling-a-comparative-pilot-study
#10
Uday P Patil, Pradeep V Mally, Elena V Wachtel
BACKGROUND: Evaluation of newborns for hypoxic ischemic encephalopathy (HIE) includes laboratory and clinical parameters, as well as amplitude integrated electroencephalogram (aEEG). Based on qualifying criteria, selective head cooling (SHC) is initiated for infants with evidence of moderate to severe HIE. However, some newborns may not qualify for hypothermia therapy based on normal aEEG. OBJECTIVE: To compare levels of serum glial fibrillary acidic protein (GFAP), ubiquitin c-terminal hydrolase-1 (UCHL-1) protein and phosphorylated axonal neurofilament heavy chain (pNF-H), in newborns who met initial screening criteria for HIE but did not qualify for head cooling, to the levels in healthy newborns...
July 3, 2018: Journal of Perinatal Medicine
https://www.readbyqxmd.com/read/29958184/reply-to-congenital-zika-syndrome-in-non-endemic-regions-a-neuroimaging-pattern-based-approach
#11
LETTER
Mohammad Zare Mehrjardi
No abstract text is available yet for this article.
June 29, 2018: Journal of Perinatal Medicine
https://www.readbyqxmd.com/read/29949516/ductus-venosus-agenesis-and-fetal-malformations-what-can-we-expect-a-systematic-review-of-the-literature
#12
REVIEW
Diana Pacheco, Otília Brandão, Nuno Montenegro, Alexandra Matias
OBJECTIVES: The ductus venosus agenesis (DVA) is a rare condition with a variable prognosis that relies partly on the presence of associated conditions. The purpose of our study was to analyze the literature regarding the post-natal outcome of fetuses with DVA associated with fetal malformations, in order to discuss the best management options for couples. DATA SOURCES: We performed a systematic review of the literature of MEDLINE and SCOPUS electronic databases in a 25-year period from 1992 to September 2017...
June 27, 2018: Journal of Perinatal Medicine
https://www.readbyqxmd.com/read/29949515/growth-and-body-composition-in-preterm-newborns-with-bronchopulmonary-dysplasia-a-cohort-study
#13
Amanda da Silva Martins, Maria Dalva Barbosa Baker Méio, Saint Clair S Gomes, Paola Azara Tabicas Lima, Brunna Grazziotti Milanesi, Maria Elisabeth Lopes Moreira
OBJECTIVE: To compare growth and body composition of preterm infants (gestational age <32 weeks) with and without bronchopulmonary dysplasia (BPD). METHODS: A prospective cohort involving three neonatal units in the public health system of the Brazilian city of Rio de Janeiro. Inclusion: newborns with gestational age <32 weeks. EXPOSURE: BPD. Anthropometric measurements were performed at birth and at 1 month of infant corrected age. Body composition was measured using an air displacement plethysmography (ADP) (PEA POD®) at 1 month of infant corrected age...
June 27, 2018: Journal of Perinatal Medicine
https://www.readbyqxmd.com/read/29949514/thromboprophylaxis-in-pregnant-women-with-thrombophilia-and-a-history-of-thrombosis
#14
Svetlana Akinshina, Alexander Makatsariya, Victoria Bitsadze, Jamilya Khizroeva, Nadine Khamani
BACKGROUND: Despite intensive research, thromboembolism still accounts for significant maternal morbidity and mortality. We examined thrombophilia in patients with thromboembolism during pregnancy and evaluated the efficiency of antithrombotic prophylaxis in patients with thrombophilia for the prevention of recurrent thromboembolism. MATERIALS AND METHODS: Sixty-eight women with a history of thromboembolism were managed during pregnancy, in light of their thrombotic history and the result of thrombophilia assessment...
June 27, 2018: Journal of Perinatal Medicine
https://www.readbyqxmd.com/read/29936490/does-rescue-cerclage-work
#15
Durai Shivani, Bin Huey Quek, Pih Lin Tan, Tagore Shephali
Rescue cervical cerclage (RCC), also known as emergency cerclage, has long been the subject of controversy. Its use in women who have a dilated cervix has been ambivalent. RCC is often considered as a salvage measure for pregnancies which are at a high risk of severe preterm delivery (PTD) or mid-trimester miscarriage. This study aims to examine and assess the efficacy of RCC and its ability to prolong pregnancy until neonatal viability is achieved. The current data suggest that RCC is associated with a longer latency period frequently resulting in better pregnancy outcomes (Namouz S, Porat S, Okun N, Windrim R, Farine D...
June 25, 2018: Journal of Perinatal Medicine
https://www.readbyqxmd.com/read/29924738/obstetrical-maternal-and-neonatal-outcomes-in-pregnancies-affected-by-muscular-dystrophy
#16
Adriano Petrangelo, Eman Alshehri, Nicholas Czuzoj-Shulman, Haim A Abenhaim
OBJECTIVE: Pregnancies in women affected by a muscular dystrophy are at an increased risk of adverse maternal and neonatal outcomes due to the effect of the disease on the muscular, cardiac and respiratory systems. We sought to evaluate the risk of adverse outcomes within a large population-based cohort study. METHODS: We used the data extracted from the Nationwide Inpatient Sample (NIS) to conduct a retrospective population-based cohort study consisting of over 12 million births that occurred in the United States between 1999 and 2013...
June 20, 2018: Journal of Perinatal Medicine
https://www.readbyqxmd.com/read/29924737/outcomes-in-oligohydramnios-the-role-of-etiology-in-predicting-pulmonary-morbidity-mortality
#17
Ashley Hesson, Elizabeth Langen
OBJECTIVE: Early-onset oligohydramnios is typically secondary to renal-urinary anomalies (RUA) or preterm premature rupture of membranes (PPROM). We compared neonatal pulmonary outcomes between these etiologies. METHODS: We conducted a retrospective cohort study of women with oligohydramnios identified before 24 completed weeks of gestation attributed to either PPROM or RUA. Patients were excluded if other fetal anomalies were noted. Respiratory morbidity was assessed by the need for oxygen at 36 corrected weeks or at hospital discharge...
June 20, 2018: Journal of Perinatal Medicine
https://www.readbyqxmd.com/read/29894302/effect-of-psychotropic-drugs-on-fetal-behavior-in-the-third-trimester-of-pregnancy
#18
Toshiyuki Hata, Kenji Kanenishi, Mohamed Ahmed Mostafa AboEllail, Nobuhiro Mori, Kosuke Koyano, Ikuko Kato, Takashi Kusaka
AIM: To assess the effect of psychotropic drugs on fetal behavior using four-dimensional (4D) ultrasound in the third trimester of pregnancy. METHODS: Fetal behavior was assessed using Kurjak's antenatal neurodevelopmental test (KANET) using 4D ultrasound between 28 and 36 weeks of gestation. Thirty healthy (control group) and 10 psychotropic-drug-administered pregnant (case group) women were studied. The total value of the KANET score and values of each parameter (eight parameters) were compared between the two groups...
June 12, 2018: Journal of Perinatal Medicine
https://www.readbyqxmd.com/read/29894301/quantification-of-fetal-myocardial-function-in-pregnant-women-with-diabetic-diseases-and-in-normal-controls-using-speckle-tracking-echocardiography-ste
#19
Nina Rolf, Laura Kerschke, Janina Braun, Maria Karina Falkenberg, Kerstin Hammer, Helen Ann Köster, Mareike Möllers, Kathrin Oelmeier de Murcia, Walter Klockenbusch, Ralf Schmitz
PURPOSE: The purpose of our study was to quantify the fetal myocardial function in pregnant women with diabetic diseases (FDM) and in normal controls (FC) using speckle tracking echocardiography (STE). METHODS: In this prospective study, the myocardial strain and dyssynchrony were analyzed using STE in a transversal four-chamber view in 180 fetuses (53 FDM, 127 FC) between 19 and 39 weeks of gestation. The measurements of the global and segmental longitudinal strain of both chambers (2C) and of the single left chamber (1C) were executed offline via QLab 10...
June 12, 2018: Journal of Perinatal Medicine
https://www.readbyqxmd.com/read/29883324/reply-to-letter-to-the-editor-by-stritzke-a-and-shah-ps-transfusion-associated-necrotizing-enterocolitis-re-evaluated-a-systematic-review-and-meta-analysis
#20
LETTER
Stientje Esther Rai, Amneet Kaur Sidhu, Rohin Jayaram Krishnan
No abstract text is available yet for this article.
June 8, 2018: Journal of Perinatal Medicine
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