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Journal of Perinatal Medicine

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https://www.readbyqxmd.com/read/27935855/estimation-of-fetal-weight-by-ultrasonography-after-preterm-premature-rupture-of-membranes-comparison-of-different-formulas
#1
Sertac Esin, Mutlu Hayran, Yusuf Aytac Tohma, Mahmut Guden, Ismail Alay, Deniz Esinler, Serdar Yalvac, Omer Kandemir
OBJECTIVE: To compare different ultrasonographic fetal weight estimation formulas in predicting the fetal birth weight of preterm premature rupture of membrane (PPROM) fetuses. METHODS: Based on the ultrasonographic measurements, the estimated fetal weight (EFW) was calculated according to the published formulas. The comparisons used estimated birth weight (EBW) and observed birth weight (OBW) to calculate the mean absolute percentage error [(EBW-OBW)/OBW×100], mean percentage error [(EBW-OBW)/OBW×100)] and their 95% confidence intervals...
December 9, 2016: Journal of Perinatal Medicine
https://www.readbyqxmd.com/read/27935854/second-trimester-maternal-serum-markers-in-the-prediction-of-preeclampsia
#2
Qiong Luo, Xiujun Han
AIM: To determine whether late second-trimester maternal serum biomarkers are useful for the prediction of preeclampsia during the third trimester, a case-control study including 33 preeclamptic and 71 healthy pregnancies was conducted. Maternal serum concentrations of placental protein 13 (PP13), pregnancy-associated plasma protein (PAPP-A), pentraxin3 (PTX3), soluble FMS-like tyrosine kinase-1 (sFlt-1), myostatin and follistatin-like-3 (FSLT-3) were measured at 24-28 weeks' gestation...
December 9, 2016: Journal of Perinatal Medicine
https://www.readbyqxmd.com/read/27914214/antithrombin-improves-the-maternal-and-neonatal-outcomes-but-not-the-angiogenic-factors-in-extremely-growth-restricted-fetuses-at-28-weeks-of-gestation
#3
Midori Fujisaki, Ken Furuta, Masanao Ohhashi, Seishi Furukawa, Yuki Kodama, Yasuyuki Kawagoe, Hiroshi Sameshima, Tsuyomu Ikenoue
AIMS: Severe preterm fetal growth restriction (FGR) remote from term is problematic. We aimed to investigate the effect of maternally-administered antithrombin on maternal and neonatal outcomes. A prospective, one-arm, pilot study was performed in 14 women with severe FGR (≤5th centile) at <28 weeks of gestation, without hypertensive disorders. Maternal plasma concentrations of soluble Feline McDonough Sarcoma (FMS)-like trypsin kinase-1 (sFlt-1) and placental growth factor (PlGF) were measured and categorized into three groups: group 1; low sFlt-1 and high PlGF, group 2; moderate sFlt-1 and low PlGF, and group 3; high sFlt-1 and low PlGF...
December 3, 2016: Journal of Perinatal Medicine
https://www.readbyqxmd.com/read/27888650/closure-of-the-cervical-os-in-patients-after-fertility-preserving-treatment-for-early-cervical-cancer-results-of-a-prospective-observational-study
#4
Mandy Mangler, Malgorzata Lanowska, Anne Bartens, Aaron Schindler, Jens-Uwe Blohmer, Dorothee Speiser
INTRODUCTION: Up to 50% of the infants delivered after radical vaginal trachelectomy (RVT) are born prematurely. An effective strategy to reduce this number could be the closure of the cervical os (CCO). PATIENTS AND METHODS: Fifteen pregnant patients who had a RVT due to early cervical cancer were included in this prospective case control study. All patients were scheduled for CCO early in the second trimester. CCO was performed in 12 patients. Their data were compared to data from 125 pregnancies after a RVT without CCO...
November 26, 2016: Journal of Perinatal Medicine
https://www.readbyqxmd.com/read/27875320/association-of-chronic-hepatitis-b-virus-infection-with-preterm-birth-our-experience-and-meta-analysis
#5
Ai-Min Cui, Jian-Guo Shao, Hai-Bo Li, Yi Shen, Zhi-Xian Chen, Sheng Zhang, Zhao-Lian Bian, Gang Qin, Xiao-Yan Cheng
OBJECTIVES: To assess the association of chronic hepatitis B virus (HBV) infection with preterm birth (PTB). METHODS: A cohort of 20,498 pregnant women (497 HBV carriers with 20,001 non-HBV controls) with normal alanine aminotransferase (ALT) levels was selected from the Obstetrics & Gynecology Hospital of Nantong University. The clinical parameters and PTB incidence were compared between HBV carriers and non-HBV subjects. For the meta-analysis, we searched the PubMed, Ovid and Cochrane Library databases for studies comparing PTB incidence between individuals with chronic HBV infection and non-HBV subjects...
November 22, 2016: Journal of Perinatal Medicine
https://www.readbyqxmd.com/read/27865094/planned-home-birth-and-the-association-with-neonatal-hypoxic-ischemic-encephalopathy
#6
Shane W Wasden, Stephen T Chasen, Jeffrey M Perlman, Jessica L Illuzzi, Frank A Chervenak, Amos Grunebaum, Heather S Lipkind
OBJECTIVE: To evaluate the association between planned home birth and neonatal hypoxic ischemic encephalopathy (HIE). METHODS: This is a case-control study in which a database of neonates who underwent head cooling for HIE at our institution from 2007 to 2011 was linked to New York City (NYC) vital records. Four normal controls per case were then randomly selected from the birth certificate data after matching for year of birth, geographic location, and gestational age...
November 19, 2016: Journal of Perinatal Medicine
https://www.readbyqxmd.com/read/27865093/maternal-endothelial-damage-as-a-disorder-shared-by-early-preeclampsia-late-preeclampsia-and-intrauterine-growth-restriction
#7
Sebastian Kwiatkowski, Barbara Dołegowska, Ewa Kwiatkowska, Rafał Rzepka, Natalia Marczuk, Beata Loj, Andrzej Torbè
INTRODUCTION: Preeclampsia (PE) and intrauterine growth restriction (IUGR) are separate disease entities that have frequently been reported as sharing the same pathogenesis. In both of them, angiogenesis disorders and generalized endothelial damage with an accompanying inflammation are the dominant symptoms. In this study, we attempted to prove that both these processes demonstrate the same profile in early PE, late PE and IUGR patients, while the only difference is in the degree of exacerbation of the lesions...
November 19, 2016: Journal of Perinatal Medicine
https://www.readbyqxmd.com/read/27855117/comparison-of-the-duo-of-insulin-like-growth-factor-binding-protein-1-alpha-fetoprotein-amnioquick-duo-%C3%A2-and-traditional-clinical-assessment-for-diagnosing-premature-rupture-of-fetal-membranes
#8
George Uchenna Eleje, Euzebus Chinonye Ezugwu, Ahizechukwu Chigoziem Eke, Joseph Ifeanyichukwu Ikechebelu, Chukwudi Celestine Obiora, Nnabuike Okechukwu Ojiegbe, Ifeanyichukwu Uzoma Ezebialu, Chukwuemeka Okwudili Ezeama, Betrand Obi Nwosu, Gerald Okanandu Udigwe, Charles Ikechukwu Okafor, Frank Okechukwu Ezugwu
PURPOSE: To determine the diagnostic accuracy of insulin-like growth factor binding protein-1/alpha fetoprotein (Amnioquick duo+®) compared with traditional clinical assessment (TCA) of nitrazine, ferning and pooling for the diagnosis of prelabor rupture of membranes (PROM). METHODS: A double-blinded, multicenter clinical study was conducted between February 2015 and August 2015 among pregnant women presenting with symptoms or features suggestive of PROM between 24 and 42 weeks gestation...
November 17, 2016: Journal of Perinatal Medicine
https://www.readbyqxmd.com/read/27845885/maternal-venous-sharp1-levels-in-preeclampsia
#9
Ali Ozgur Ersoy, Efser Oztas, Sibel Ozler, Aytekin Tokmak, Ebru Ersoy, Merve Ergin, Nuri Danisman
AIM: Owing to its mysterious etiology, pathogenesis of preeclampsia (PE) remains controversial. Here we aimed to compare the levels of an angiogenesis marker, split and hairy related protein-1 (SHARP1), in PE vs. normal pregnancy. METHODS: Thirty-one patients with early-onset PE (EOPE), 26 patients with late-onset PE (LOPE), and 33 patients as a control group were recruited for this study in a tertiary referral center in Ankara, Turkey. Maternal venous SHARP1 levels and individual characteristics of the three groups were compared...
November 15, 2016: Journal of Perinatal Medicine
https://www.readbyqxmd.com/read/27831924/transient-fetal-blood-redistribution-associated-with-maternal-supine-position
#10
Karina P Silva, Tatiana Emy N K Hamamoto, Roseli M Y Nomura
OBJECTIVE: To investigate whether fetal blood circulation is influenced by the maternal supine position. METHODS: The inclusion criteria were good health, a singleton pregnancy, maternal age between 18 and 40 years, gestational age between 36 and 40 weeks, and an agreement to participate in the study. Each participant (n=20) was initially asked to adopt the left lateral position for 5 min, while fetal Doppler measurements were taken of the fetal middle cerebral artery (MCA), umbilical artery (UA), and umbilical vein (UV)...
November 10, 2016: Journal of Perinatal Medicine
https://www.readbyqxmd.com/read/27831923/perinatal-death-associated-with-umbilical-cord-prolapse
#11
Mark P Hehir, Lucia Hartigan, Rhona Mahony
OBJECTIVE: Umbilical cord prolapse occurs when the cord prolapses ahead of or alongside the presenting part. It is an acute obstetric emergency with potential catastrophic effects. We set out to assess incidence of cord prolapse, as well as rates and characteristics of perinatal death associated with the condition. STUDY DESIGN: This was a retrospective cohort study. All recorded cases of cord prolapse were included, and rates of perinatal death and encephalopathy, as well as intrapartum and maternal characteristics were examined...
November 10, 2016: Journal of Perinatal Medicine
https://www.readbyqxmd.com/read/27824616/increased-rates-of-cesarean-sections-and-large-families-a-potentially-dangerous-combination
#12
Ahmed M Saleh, Joachim W Dudenhausen, Badreldeen Ahmed
Rates of cesarean sections have been on the rise over the past three decades all over the world, despite the ideal rate of 10-15% that had been set by the World Health Organization (WHO) in 1985, in Fortaleza, Brazil. This epidemic increase in the rate of cesarean delivery is due to many factors which include, cesarean delivery on request, advanced maternal age at first pregnancy, decrease in number of patients who are willing to try vaginal birth after cesarean delivery, virtual disappearance of vaginal breech delivery, perceived increase in the weight of the fetus and increase in the number of women with chronic medical conditions such as Diabetes Mellitus and congenital heart disease in the reproductive age...
November 8, 2016: Journal of Perinatal Medicine
https://www.readbyqxmd.com/read/27805908/twin-pregnancy-in-women-above-the-age-of-45-years-maternal-and-neonatal-outcomes
#13
Tomer Avnon, Alon Haham, Ariel Many
Childbearing age continues to rise and, with the increasing implementation of assisted reproductive technology (ART), the number of multiple pregnancies has also risen. This is a retrospective cohort study on maternal and neonatal outcomes of the twin pregnancies of 57 women aged ≥45 years compared to 114 younger women who gave birth in our institution between January 2011 and August 2015. Data were extracted from the real-time computerized database. The rates of hypertensive complications and pre-eclampsia (PE) were much higher in the study group compared to the controls (24/57 vs...
November 2, 2016: Journal of Perinatal Medicine
https://www.readbyqxmd.com/read/27780155/the-importance-of-clinically-and-ethically-fine-tuning-decision-making-about-cesarean-delivery
#14
Michelle T Nguyen, Laurence B McCullough, Frank A Chervenak
In obstetric practice, each pregnant woman presents with a composite of maternal and fetal characteristics that can alter the risk of significant harm without cesarean intervention. The hospital's availability of resources and the obstetrician's training, experience, and skill level can also alter the risk of significant harm without cesarean intervention. This paper proposes a clinical ethical framework that takes these clinical and organizational factors into account, to promote a deliberative rather than simplistic approach to decision-making and counseling about cesarean delivery...
October 25, 2016: Journal of Perinatal Medicine
https://www.readbyqxmd.com/read/27780154/maternal-and-neonatal-outcomes-following-expectant-management-of-preterm-prelabour-rupture-of-membranes-before-viability
#15
Winnie Huiyan Sim, Edward Araujo Júnior, Fabricio Da Silva Costa, Penelope Marie Sheehan
AIM: To assess the contemporary maternal and neonatal outcomes following expectant management of preterm premature rupture of membranes (PPROM) prior to 24 weeks' gestation and to identify prognostic indicators of this morbid presentation. METHODS: We performed a systematic review in the Pubmed and EMBASE databases to identify the primary (perinatal mortality, severe neonatal morbidity and serious maternal morbidity) and secondary (neonatal survival and morbidity) outcomes following expectant management of previable PPROM...
October 25, 2016: Journal of Perinatal Medicine
https://www.readbyqxmd.com/read/27771626/pregnancy-outcomes-regarding-maternal-serum-afp-value-in-second-trimester-screening
#16
Karolina Bartkute, Dalia Balsyte, Josef Wisser, Juozas Kurmanavicius
AIM: The aim of this study was to evaluate the predictive value of α-fetoprotein in maternal serum (MS-AFP) as a marker for diverse pregnancy outcomes. METHODS: The study was based on pregnancy and delivery data from 5520 women between 1999 and 2014 at University Hospital of Zurich (UHZ). INCLUSION CRITERIA: both MS-AFP and pregnancy outcome were known for the same pregnancy. Pregnancy outcomes and characteristics such as fetal malformation, intrauterine fetal death (IUFD) and intrauterine growth retardation as well as maternal age, weight before pregnancy, gestational age (GA) at delivery, newborn weight, length and head circumference were analyzed with respect to the MS-AFP value...
October 24, 2016: Journal of Perinatal Medicine
https://www.readbyqxmd.com/read/27768584/maternal-complications-in-settings-where-two-thirds-of-extremely-preterm-births-are-delivered-by-cesarean-section
#17
Susanne Hesselman, Maria Jonsson, Eva-Britta Råssjö, Monika Windling, Ulf Högberg
OBJECTIVE: To investigate the maternal complications associated with cesarean section (CS) in the extremely preterm period according to the gestational week (GW) and to indication of delivery. STUDY DESIGN: This is a retrospective case-referent study with a review of medical records of women who delivered at 22-27 weeks of gestation (n=647) at two level III units in Sweden. For abdominal delivery, gestational length was stratified into 22-24 (n=105) and 25-27 (n=301) weeks...
October 21, 2016: Journal of Perinatal Medicine
https://www.readbyqxmd.com/read/27763883/clinical-chorioamnionitis-at-term-vii-the-amniotic-fluid-cellular-immune-response
#18
Alicia Martinez-Varea, Roberto Romero, Yi Xu, Derek Miller, Ahmed I Ahmed, Piya Chaemsaithong, Noppadol Chaiyasit, Lami Yeo, Majid Shaman, Kia Lannaman, Benjamin Cher, Sonia S Hassan, Nardhy Gomez-Lopez
OBJECTIVES: 1) To characterize the cellular composition of the amniotic fluid of patients diagnosed with clinical chorioamnionitis at term, as a function of the presence or absence of microorganisms determined by cultivation techniques, and 2) to characterize the cytokine production by white blood cells present in the amniotic fluid using flow cytometry-based techniques. MATERIALS AND METHODS: Amniotic fluid samples from 20 women who had the diagnosis of clinical chorioamnionitis at term were analyzed using cultivation techniques (for aerobic and anaerobic bacteria as well as genital Mycoplasmas)...
October 20, 2016: Journal of Perinatal Medicine
https://www.readbyqxmd.com/read/27754969/underlying-causes-of-neonatal-deaths-in-term-singleton-pregnancies-home-births-versus-hospital-births-in-the-united-states
#19
Amos Grünebaum, Laurence B McCullough, Birgit Arabin, Joachim Dudenhausen, Brooke Orosz, Frank A Chervenak
INTRODUCTION: The objective of this study was to evaluate the underlying causes of neonatal mortality (NNM) in midwife-attended home births and compare them to hospital births attended by a midwife or a physician in the United States (US). METHODS: A retrospective cohort study of the Centers for Disease Control (CDC) linked birth/infant death data set (linked files) for 2008 through 2012 of singleton, term (≥37 weeks) births and normal newborn weights (≥2500 grams)...
October 18, 2016: Journal of Perinatal Medicine
https://www.readbyqxmd.com/read/27718495/risk-of-recurrent-preterm-birth-among-women-according-to-change-in-partner
#20
Rebecca J Baer, Juan Yang, Christina D Chambers, Kelli K Ryckman, Audrey F Saftlas, Vincenzo Berghella, Chris Dunkel Schetter, Gary M Shaw, David K Stevenson, Laura L Jelliffe-Pawlowski
There is well-established literature indicating change in partner as a risk for preeclampsia, yet the research on the risk of preterm birth after a change in partners has been sparse and inconsistent. Using a population of California live born singletons, we aimed to determine the risk of preterm birth after a change in partner between the first and second pregnancies. The risk of preterm and early term delivery in the second pregnancy was calculated for mothers who did or did not change partners between births with the referent group as women who delivered both pregnancies at term and did not change partners...
October 8, 2016: Journal of Perinatal Medicine
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