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Journal of Perinatal Medicine

Elinor Charles, Katie A Hunt, Christopher Harris, Ann Hickey, Anne Greenough
Background Small for gestational age (SGA) infants are less likely to develop respiratory distress syndrome (RDS), but more likely to develop bronchopulmonary dysplasia (BPD) and have a higher mortality. Our aim was to focus on outcomes of those with a birth weight less than or equal to 750 g. Methods The mortality, BPD severity, necrotising enterocolitis (NEC), home oxygen requirement and length of hospital stay were determined according to SGA status of all eligible infants in a 5-year period admitted within the first 24 h after birth...
October 18, 2018: Journal of Perinatal Medicine
Dragan Soldo, Mikulić-Kajić Matija, Spalldi Barišić Lara, Penava Nikolina, Orlović Martina, Soldo Neven, Kajić Martin
Background The objective of the study was to compare the effect of eicosapentaenoic acid (EPA) and docosahexaenoic acid (DHA) dietary supplementation on their concentration in total lipids (TL) and lipid fractions of maternal and umbilical vein (UV) blood. The specific objective was to analyze the impact of EPA and DHA supplementation on pregnancy outcome and neonatal birth weight. Methods Women were randomly single-blinded (randomized controlled trial; ISRCTN36705743) allocated to the group receiving EPA and DHA supplementation (supplemented group) or the group receiving placebo-corn oil (control group) in the time period from January 1st, 2016 until March 1st, 2017...
October 13, 2018: Journal of Perinatal Medicine
Siobhan Enright, Sonia Varadkar, Alison Demaio, Catherine Flynn, Fionnuala Ni Áinle, Mark P Hehir
Background Hemorrhage is a critical contributor to maternal morbidity but estimation of blood loss at delivery is frequently inaccurate. Due to this inaccuracy we sought to examine blood transfusion as a surrogate marker for morbidity in a large non-population based consecutive cohort. Methods A retrospective analysis of prospectively gathered data was carried out at two university institutions serving a heterogeneous urban obstetric population from January to December 2016. Data were analyzed to determine whether individual characteristics were associated with perinatal transfusion...
October 4, 2018: Journal of Perinatal Medicine
M Voigt, Hans-Peter Hagenah, Mirjam Kunze, Ursula Wittwer-Backofen, Dirk Manfred Olbertz, Sebastian Staube
Aim To investigate the variability in the prevalences of selected birth risks in women of different heights and weights. Materials and methods Data from the German Perinatal Survey of 1998-2000 were analyzed: 503,468 cases contributed to our analysis of the prevalences of selected birth risks specified according to maternal weight groups, 502,562 cases contributed to our analysis according to maternal height groups and 43,928 cases contributed to our analysis of birth risks in women with a body mass index (BMI) of 21-23 kg/m2 but different heights and weights...
October 1, 2018: Journal of Perinatal Medicine
Percy Pacora, Roberto Romero, Sunil Jaiman, Offer Erez, Gaurav Bhatti, Bogdan Panaitescu, Neta Benshalom-Tirosh, Eun Jung Jung, Chaur-Dong Hsu, Sonia S Hassan, Lami Yeo, Nicholas Kadar
Objectives To investigate mechanisms of in utero death in normally formed fetuses by measuring amniotic fluid (AF) biomarkers for hypoxia (erythropoietin [EPO]), myocardial damage (cardiac troponin I [cTnI]) and brain injury (glial fibrillary acidic protein [GFAP]), correlated with risk factors for fetal death and placental histopathology. Methods This retrospective, observational cohort study included intrauterine deaths with transabdominal amniocentesis prior to induction of labor. Women with a normal pregnancy and an indicated amniocentesis at term were randomly selected as controls...
September 19, 2018: Journal of Perinatal Medicine
Diana Garretto, Youn-Kyung Kim, Loredana Quadro, Rebekah R Rhodas, Veronica Pimentel, Natalie A Crnosija, Lizhou Nie, Peter Bernstein, Pamela Tropper, Genevieve S Neal-Perry
Background As breastfeeding awareness and social acceptance are increased, maternal nutritional deficiency requires more investigation. Methods A prospective cohort study was conducted to determine if vitamin A deficiency is more common in pregnant, lactating post-bariatric surgery women in an inner city population. Antepartum, women after bariatric surgery and controls with no history of malabsorption were recruited. Third trimester, postpartum maternal blood and cord blood were collected as well as three breast milk samples: colostrum, transitional and mature milk...
September 19, 2018: Journal of Perinatal Medicine
Ismail Tekesin
Objectives To assess the diagnostic value of an early anomaly scan in fetuses with increased nuchal translucency (NT) in the prediction of aneuploidy. Methods In this study we analyzed the data of pregnant women obtained at their first trimester screening in our unit. The detailed examination routinely includes measurement of NT and a scan for anatomical defects. For fetuses with an NT≥3.5 mm, the diagnostic power of early major sonographic findings (MSF) regarding abnormal karyotype was calculated. Results A total of 7352 first trimester examinations were screened...
September 15, 2018: Journal of Perinatal Medicine
Bernhard Stoiber, Christian Haslinger, Marie Kristin Schäffer, Roland Zimmermann, Leonhard Schäffer
Objectives To measure the tocolytic effect of the combination of the oxytocin receptor antagonist atosiban with the β-mimetic agent fenoterol on human myometrium of pregnant women. Methods An in vitro study of contractility in human myometrium at the Laboratory of the Department of Obstetrics, University Hospital of Zürich, Switzerland, was performed. Thirty-six human myometrial biopsies were obtained during elective caesarean sections of singleton pregnancies at term. Tissue samples were exposed to atosiban, fenoterol and the combination of atosiban with fenoterol...
September 15, 2018: Journal of Perinatal Medicine
Cecilia Villalaín, Ignacio Herraiz, Maria S Quezada, Paula I Gómez-Arriaga, Elisa Simón, Enery Gómez-Montes, Alberto Galindo
Objectives As conflicting results have been reported about the association of reversed flow on the aortic isthmus (AoI) and adverse perinatal results in fetal growth restriction (FGR), we aim to compare perinatal outcomes (including tolerance to labor induction) of late-onset FGR between those with anterograde and reversed AoI flow. Methods This was an observational retrospective cohort study on 148 singleton gestations diagnosed with late-onset FGR (diagnosis ≥32+0 weeks), with an estimated fetal weight (EFW) <10th centile and mild fetal Doppler alteration: umbilical artery (UA) pulsatility index (PI) >95th centile, middle cerebral artery (MCA)-PI <5th centile or cerebral-placental ratio <5th centile...
September 13, 2018: Journal of Perinatal Medicine
Paula J Correa, Pia Venegas, Yasna Palmeiro, Daniela Albers, Gregory Rice, Jaime Roa, Jorge Cortez, Max Monckeberg, Manuel Schepeler, Eduardo Osorio, Sebastian E Illanes
No abstract text is available yet for this article.
September 6, 2018: Journal of Perinatal Medicine
Marciali Gonçalves Fonseca Silva, Michele Lima Gregório, Moacir Fernandes de Godoy
No abstract text is available yet for this article.
September 5, 2018: Journal of Perinatal Medicine
Amelie de Gregorio, Thomas W P Friedl, Christoph Scholz, Wolfgang Janni, Florian Ebner, Nikolaus de Gregorio
No abstract text is available yet for this article.
September 4, 2018: Journal of Perinatal Medicine
Katharina Redling, Sabine Schaedelin, Evelyn Annegret Huhn, Irene Hoesli
No abstract text is available yet for this article.
September 4, 2018: Journal of Perinatal Medicine
Iris Kračun, Nataša Tul, Isaac Blickstein, Vislava Globevnik Velikonja
No abstract text is available yet for this article.
August 29, 2018: Journal of Perinatal Medicine
Marianne U Huun, Håvard T Garberg, Giuseppe Buonocore, Mariangela Longini, Elisa Belvisi, Francesco Bazzini, Fabrizio Proietti, Ola Didrik Saugstad, Rønnaug Solberg
No abstract text is available yet for this article.
August 15, 2018: Journal of Perinatal Medicine
Toshiyuki Hata, Kenji Kanenishi, Nobuhiro Mori, Mohamed Ahmed Mostafa AboEllail, Uiko Hanaoka, Kosuke Koyano, Ikuko Kato, Takashi Kusaka
Objective To assess the usefulness of the antenatal fetal neurodevelopmental test for the prediction of postnatal developmental disabilities. Methods Fetal behavior was assessed with Kurjak's antenatal neurodevelopmental test (KANET) using four-dimensional ultrasound between 28 and 38 weeks of gestation. A score range of 0-5 was characterized as abnormal, from 6 to 9 was considered borderline, and 10-16 was normal. After birth, follow-up was conducted for at least 2 years in all fetuses. Results There were 337 normal (95...
August 11, 2018: Journal of Perinatal Medicine
André Sander, Roland Wauer
Background The infant mortality rate (IMR), a key indicator of the quality of a healthcare system, has remained at approximately 3.5‰ for the past 10 years in Germany. Generic quality indicators (QIs), as used in Germany since 2010, greatly help in ensuring such a good value but do not seem to be able to further reduce the IMR. The neonatal mortality rate (NMR) contributes to 65-70% of the IMR. We therefore propose single-case analysis of neonatal deaths as an additional method and show an efficient way to implement this approach...
August 1, 2018: Journal of Perinatal Medicine
Isabella Piva, Piergiorgio Iannone, Danila Morano, Pantaleo Greco
Fetomaternal hemorrhage (FMH) is an obstetrical challenge. It is defined as a passage of fetal blood into the maternal circulation or vice versa, which might complicate pregnancy or delivery. Most cases of acute and chronic FMH are idiopathic in origin and involve uncomplicated near-term pregnancies. Yet, due to the lack of universal screening, heterogeneous clinical presentation and insufficient clinicians awareness, in some cases FMH may present as immediate fetal compromise or even stillbirth as the most devastating consequence...
July 27, 2018: Journal of Perinatal Medicine
Anju Suhag, Vincenzo Berghella
No abstract text is available yet for this article.
October 25, 2018: Journal of Perinatal Medicine
Dirk Manfred Olbertz, Asja Knie, Sebastian Straube, Roland Hentschel, Ekkehard Schleußner, Hans-Peter Hagenah, Jan Däbritz, Manfred Voigt
We investigated the effects of maternal age, body weight, body height, weight gain during pregnancy, smoking during pregnancy, previous live births and being a single mother on somatic development at birth. We analysed data from the German Perinatal Survey for the years 1998-2000 from eight German federal states. We had available data on 508,926 singleton pregnancies and neonates in total; for 508,893 of which we could classify the neonates as small, appropriate or large for gestational age (SGA, AGA or LGA) based on the 10th and 90th birth weight percentiles...
October 25, 2018: Journal of Perinatal Medicine
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