Oriella Gnarra, Julia van der Meer, Jan D Warncke, Livia G Fregolente, Elena Wenz, Kseniia Zub, Uchendu Nwachukwu, Zhongxing Zhang, Ramin Khatami, Sigrid von Manitius, Silvia Miano, Jens Acker, Mathias Strub, Robert Riener, Claudio L A Bassetti, Markus H Schmidt
The Swiss Primary Hypersomnolence and Narcolepsy Cohort Study (SPHYNCS) is a multicenter research initiative to identify new biomarkers in central disorders of hypersomnolence (CDH). Whereas narcolepsy type 1 (NT1) is well characterized, other CDH disorders lack precise biomarkers. In SPHYNCS, we utilized Fitbit smartwatches to monitor physical activity, heart rate, and sleep parameters over one year. We examined the feasibility of long-term ambulatory monitoring using the wearable device. We then explored digital biomarkers differentiating patients with NT1 from healthy controls (HC)...
March 29, 2024: Sleep