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https://www.readbyqxmd.com/read/28655183/three-year-follow-up-comparing-cognitive-behavioral-therapy-for-depression-to-cognitive-behavioral-therapy-for-insomnia-for-patients-with-both-diagnoses
#1
Kerstin Blom, Susanna Jernelöv, Christian Rück, Nils Lindefors, Viktor Kaldo
This three-year follow-up compared insomnia treatment to depression treatment for patients with both diagnoses. Forty-three participants were randomized to either treatment, in the form of Internet-delivered therapist-guided cognitive behavior therapy, and 37 (86%) provided primary outcome data at the three-year follow-up. After three years, reductions on depression severity were similar in both groups (between-group effect-size, d = 0.33, p = .45), while the insomnia treatment had superior effects on insomnia severity (d = 0...
June 24, 2017: Sleep
https://www.readbyqxmd.com/read/28651371/sleep-and-physiological-dysregulation-a-closer-look-at-sleep-intraindividual-variability
#2
Bei Bei, Teresa E Seeman, Judith E Carroll, Joshua F Wiley
Study Objectives: Variable daily sleep (i.e., higher intraindividual variability; IIV) is associated with negative health consequences, but potential physiological mechanisms are poorly understood. This study examined the associations between sleep timing, duration, and quality IIV and physiological dysregulation, with diurnal cortisol trajectories as a proximal outcome, and allostatic load (AL) as a multi-system distal outcome. Methods: Participants are 436 adults (Mage±SD=54...
June 23, 2017: Sleep
https://www.readbyqxmd.com/read/28651358/rem-sleep-theta-changes-in-frequent-nightmare-recallers
#3
Louis-Philippe Marquis, Tyna Paquette, Cloé Blanchette-Carrière, Gaëlle Dumel, Tore Nielsen
The sleep of individuals suffering from frequent non-traumatic nightmares (NM) could prove useful in uncovering neural mechanisms involved in NM production. Past research has shown enhanced relative 10-14.5Hz activity ('high alpha') during REM sleep in frequent NM recallers, while other findings are consistent with a role for theta activity in REM-dependent memory processing. To replicate and expand upon this study, we computed spectral activity for sleep and wake EEG recordings from 18 frequent NM recallers and 15 control participants...
June 23, 2017: Sleep
https://www.readbyqxmd.com/read/28651353/protein-tyrosine-phosphatase-1b-mediates-sleep-fragmentation-induced-insulin-resistance-and-visceral-adipose-tissue-inflammation-in-mice
#4
David Gozal, Abdelnaby Khalyfa, Zhuanghong Qiao, Mahzad Akbarpour, Rosanna Maccari, Rosaria Ottanà
Study Objectives: Sleep fragmentation (SF) is highly prevalent and has emerged as an important contributing factor to obesity and metabolic syndrome. We hypothesized that SF-induced increases in protein tyrosine phosphatase-1B (PTP-1B) expression and activity underlie increased food intake, inflammation, and leptin and insulin resistance. Methods: Wild type (WT) and ObR-PTP-1b-/- mice (Tg) were exposed to SF and control sleep (SC), and food intake was monitored...
June 23, 2017: Sleep
https://www.readbyqxmd.com/read/28645184/early-menarche-and-menstrual-problems-are-associated-with-sleep-disturbance-in-a-large-sample-of-chinese-adolescent-girls
#5
Xianchen Liu, Hua Chen, Zhen-Zhen Liu, Fang Fan, Cun-Xian Jia
Study Objectives: Little is known about the association between menstruation and sleep disturbance in adolescent girls. This study examined sleep duration, insomnia symptoms, and sleep quality in relation to age at menarche and menstrual problems in a large sample of Chinese adolescent girls. Methods: This report represents the baseline data of an ongoing longitudinal study of the Shandong Adolescent Behavior & Health Cohort (SABHC) in Shandong, China. 5,800 12 to 18-year-old girls (mean age= 15...
June 22, 2017: Sleep
https://www.readbyqxmd.com/read/28645156/rem-sleep-behavior-disorder-and-cognitive-impairment-in-parkinson-s-disease
#6
Natalia Jozwiak, Ronald B Postuma, Jacques Montplaisir, Véronique Latreille, Michel Panisset, Sylvain Chouinard, Pierre-Alexandre Bourgouin, Jean-François Gagnon
Study Objectives: REM sleep behavior disorder (RBD) is a parasomnia affecting 33 to 46% of patients with Parkinson's disease (PD). The existence of a unique and specific impaired cognitive profile in PD patients with RBD is still controversial. We extensively assessed cognitive functions to identify whether RBD is associated with more severe cognitive deficits in nondemented patients with PD. Methods: One hundred and sixty-two participants, including 53 PD patients with RBD, 40 PD patients without RBD, and 69 healthy subjects, underwent polysomnography, a neurological assessment, and an extensive neuropsychological exam to assess attention, executive functions, episodic learning and memory, visuospatial abilities, and language...
June 22, 2017: Sleep
https://www.readbyqxmd.com/read/28637196/chronological-change-of-right-ventricle-by-chronic-intermittent-hypoxia-in-mice
#7
Hyung-Ju Cho, Woon Heo, Jung Woo Han, Yong Hyuk Lee, Jin Myung Park, Min Jung Kang, Joo-Heon Yoon, Min Goo Lee, Chang-Hoon Kim, Joo Young Kim
Study Objective: No studies have investigated sequential changes in the heart on MRI, along with observation of functional lung phenotypes and genetics, over the duration of chronic intermittent hypoxia (CIH). We investigated chronological changes in heart and lung phenotypes after CIH using a mouse model to provide new insights into the pathophysiology of sleep apnea-induced cardiovascular disease. Methods: C57BL/6J adult male mice were randomized to 4 weeks or 8 weeks of CIH...
June 20, 2017: Sleep
https://www.readbyqxmd.com/read/28633495/estradiol-protects-against-cardio-respiratory-dysfunctions-and-oxidative-stress-in-intermittent-hypoxia
#8
Sofien Laouafa, Alexandra Ribon-Demars, François Marcouiller, Damien Roussel, Aida Bairam, Vincent Pialoux, Vincent Joseph
Study Objectives: We tested the hypothesis that estradiol (E2) protects against cardio-respiratory disorders and oxidative stress induced by chronic intermittent hypoxia (CIH) in adult female rats. Methods: Sprague-Dawley female rats (230-250g) were ovariectomized (OVX) and implanted with osmotic pumps delivering vehicle (Veh) or E2 (0.5 mg/kg/day). After 14 days of recovery, the rats were exposed to chronic CIH (21%-10% O2 - 8 hours/day - 10 cycles/hour) or room air (RA)...
June 19, 2017: Sleep
https://www.readbyqxmd.com/read/28633493/corrigendum
#9
(no author information available yet)
No abstract text is available yet for this article.
June 19, 2017: Sleep
https://www.readbyqxmd.com/read/28605546/plasticity-related-gene-expression-during-eszopiclone-induced-sleep
#10
Dmitry Gerashchenko, Ravi K Pasumarthi, Thomas S Kilduff
Study Objectives: Experimental evidence suggests that restorative processes depend on synaptic plasticity changes in the brain during sleep. We used the expression of plasticity-related genes to assess synaptic plasticity changes during drug-induced sleep. Methods: We first characterized sleep induced by eszopiclone in mice during baseline conditions and during the recovery from sleep deprivation. We then compared the expression of 18 genes and 2 miRNAs critically involved in synaptic plasticity in these mice...
June 12, 2017: Sleep
https://www.readbyqxmd.com/read/28605521/recorded-and-reported-sleepiness-the-association-between-brain-arousal-in-resting-state-and-subjective-daytime-sleepiness
#11
Philippe Jawinski, Jennifer Kittel, Christian Sander, Jue Huang, Janek Spada, Christine Ulke, Kerstin Wirkner, Tilman Hensch, Ulrich Hegerl
Objectives: Daytime sleepiness is a significant public health concern. Early evidence points towards the computerized VIGALL (Vigilance Algorithm Leipzig) as time-efficient tool to assess sleepiness objectively. In the present study, we investigated the association between VIGALL variables of EEG-vigilance (indicating brain arousal in resting state) and subjective daytime sleepiness in the LIFE cohort study. Additionally, we validated VIGALL against the self-rated likelihood of having fallen asleep during the conducted resting EEG and against heart periods...
June 12, 2017: Sleep
https://www.readbyqxmd.com/read/28575510/externalizing-behaviors-and-callous-unemotional-traits-different-associations-with-sleep-quality
#12
Dan Denis, Reece Akhtar, Benjamin C Holding, Christina Murray, Jennifer Panatti, Gordon Claridge, Avi Sadeh, Nicola L Barclay, Rachael O'Leary, Barbara Maughan, Tom A McAdams, Richard Rowe, Thalia C Eley, Essi Viding, Alice M Gregory
Study Objectives: Sleep quality is associated with different aspects of psychopathology, but relatively little research has examined links between sleep quality and externalizing behaviors or callous-unemotional traits. We examined: (1) whether an association exists between sleep quality and externalizing behaviors; (2) whether anxiety mediates this association; (3) whether callous-unemotional traits are associated with sleep quality. Methods: Data from two studies were used...
June 1, 2017: Sleep
https://www.readbyqxmd.com/read/28575467/arousability-and-fall-risk-during-forced-awakenings-from-nocturnal-sleep-among-healthy-males-following-administration-of-zolpidem-10-mg-and-doxepin-6-mg-a-randomized-placebo-controlled-four-way-crossover-trial
#13
Christopher L Drake, Heith Durrence, Philip Cheng, Thomas Roth, Vivek Pillai, Edward L Peterson, Meeta Singh, Kieulinh Michelle Tran
Study Objectives: To examine and compare the arousability threshold and fall risk upon awakening of doxepin (6 mg) versus zolpidem (10 mg). Methods: A total of 52 healthy adult males were included in a double-blind, placebo-controlled, 4-way crossover study. The experimental procedure included four nights with polysomnography in the lab (zolpidem, doxepin, and their respective placebo conditions). Arousability was measured using an auditory awakening threshold delivered at the peak-plasma concentration for the active hypnotics and at matched times for the respective placebo conditions...
June 1, 2017: Sleep
https://www.readbyqxmd.com/read/28541527/sleep-dependent-modulation-of-metabolic-rate-in-drosophila
#14
Bethany A Stahl, Melissa E Slocumb, Hersh Chaitin, Justin R Diangelo, Alex C Keene
Dysregulation of sleep is associated with metabolic diseases, and metabolic rate is acutely regulated by sleep-wake behavior. In humans and rodent models, sleep loss is associated with obesity, reduced metabolic rate, and negative energy balance, yet little is known about the neural mechanisms governing interactions between sleep and metabolism. We have developed a system to simultaneously measure sleep and metabolic rate in individual Drosophila, allowing for interrogation of neural systems governing interactions between sleep and metabolic rate...
May 25, 2017: Sleep
https://www.readbyqxmd.com/read/28541519/reduced-sleep-during-social-isolation-leads-to-cellular-stress-and-induction-of-the-unfolded-protein-response-upr
#15
Marishka K Brown, Ewa Strus, Nirinjini Naidoo
Study Objectives: Social isolation has a multitude of negative consequences on human health including the ability to endure challenges to the immune system, sleep amount and efficiency, and general morbidity and mortality. These adverse health outcomes are conserved in other social species. In the fruit fly Drosophila melanogaster, social isolation leads to increased aggression, impaired memory and reduced amounts of daytime sleep. There is a correlation between molecules affected by social isolation and those implicated in sleep in Drosophila...
May 25, 2017: Sleep
https://www.readbyqxmd.com/read/28541508/self-efficacy-and-short-term-adherence-to-continuous-positive-airway-pressure-treatment-in-children
#16
Melissa S Xanthopoulos, Ji Young Kim, Michael Blechner, Ming-Yu Chang, Mary Kate Menello, Christina Brown, Edward Matthews, Terri E Weaver, Justine Shults, Carole L Marcus
Study Objectives: Infants, children and adolescents are increasingly being prescribed continuous positive airway pressure (CPAP) for treatment of obstructive sleep apnea (OSAS), yet adherence is often poor. The purpose of this study was to examine the relationship between caregiver and patient-reported health cognitions about CPAP prior to starting CPAP, and CPAP adherence at one month. We hypothesized that greater caregiver-reported self-efficacy would be positively associated with CPAP adherence in children...
May 24, 2017: Sleep
https://www.readbyqxmd.com/read/28541436/changes-in-sleep-duration-during-transition-to-statutory-retirement-a-longitudinal-cohort-study
#17
Saana Myllyntausta, Paula Salo, Erkki Kronholm, Ville Aalto, Mika Kivimäki, Jussi Vahtera, Sari Stenholm
Study Objectives: This study examined whether sleep duration changes during the transition from full-time work to statutory retirement and, if this were the case, which pre-retirement factors, including sociodemographic, work, lifestyle and health factors, predict these changes. Methods: Data from repeated surveys of the Finnish Public Sector study, linked to records of retirement, were used. The study population consisted of 5,785 participants who retired on a statutory basis in 2000-2011 and who had responded to surveys on sleep duration at least once immediately before and after their retirement (mean number of repeat study waves 3...
May 24, 2017: Sleep
https://www.readbyqxmd.com/read/28531336/loop-gain-predicts-the-response-to-upper-airway-surgery-in-patients-with-obstructive-sleep-apnoea-ventilatory-control-abnormalities-predict-surgical-responsiveness
#18
Simon A Joosten, Paul Leong, Shane A Landry, Scott A Sands, Philip I Terrill, Dwayne Mann, Anthony Turton, Jhanavi Rangaswamy, Christopher Andara, Glen Burgess, Darren Mansfield, Garun S Hamilton, Bradley A Edwards
Study Objectives: Upper airway surgery is often recommended to treat OSA patients who cannot tolerate continuous positive airways pressure (CPAP). However, the response to surgery is variable, potentially because it does not improve the non-anatomical factors (i.e. loop gain and arousal threshold) causing OSA. Measuring these traits clinically might predict responses to surgery. Our primary objective was to test the value of loop gain and arousal threshold to predict surgical success defined as 50% reduction in apnea-hypopnea index (AHI) and AHI <10 events/hr post-surgery...
May 22, 2017: Sleep
https://www.readbyqxmd.com/read/28531332/are-sleep-problems-a-risk-factor-for-the-onset-of-musculoskeletal-pain-in-children-and-adolescents-a-systematic-review
#19
Alessandro Andreucci, Paul Campbell, Kate M Dunn
Study objectives: Musculoskeletal pain is a major burden on society. Adults with sleep problems are at higher risk for musculoskeletal pain onset, but there is no evidence for this relationship in children and adolescents. This study aimed to systematically review prospective studies on the risk for musculoskeletal pain onset in children and adolescents with sleep problems. Methods: Five databases (MEDLINE, PsycINFO, AMED, EMBASE, HMIC) were systematically searched to identify prospective studies that investigated if children and adolescents (aged 6-19 years) with sleep problems are at higher risk for musculoskeletal pain onset...
May 20, 2017: Sleep
https://www.readbyqxmd.com/read/28525646/sleep-during-menopausal-transition-a-six-year-follow-up
#20
Laura Lampio, Päivi Polo-Kantola, Sari-Leena Himanen, Samu Kurki, Eero Huupponen, Janne Engblom, Olli J Heinonen, Olli Polo, Tarja Saaresranta
Study Objectives: Menopausal transition is associated with increased dissatisfaction with sleep, but the effects on sleep architecture are conflicting. This prospective six-year follow-up study was designed to evaluate the changes in sleep stages and sleep continuity that occur in women during menopausal transition. Methods: Sixty women (mean age 46.0 years, SD 0.9) participated. All women were premenopausal at baseline, and at the six-year follow-up, women were in different stages of menopausal transition...
May 19, 2017: Sleep
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