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https://www.readbyqxmd.com/read/28531336/loop-gain-predicts-the-response-to-upper-airway-surgery-in-patients-with-obstructive-sleep-apnoea-ventilatory-control-abnormalities-predict-surgical-responsiveness
#1
Simon A Joosten, Paul Leong, Shane A Landry, Scott A Sands, Philip I Terrill, Dwayne Mann, Anthony Turton, Jhanavi Rangaswamy, Christopher Andara, Glen Burgess, Darren Mansfield, Garun S Hamilton, Bradley A Edwards
Study Objectives: Upper airway surgery is often recommended to treat OSA patients who cannot tolerate continuous positive airways pressure (CPAP). However, the response to surgery is variable, potentially because it does not improve the non-anatomical factors (i.e. loop gain and arousal threshold) causing OSA. Measuring these traits clinically might predict responses to surgery. Our primary objective was to test the value of loop gain and arousal threshold to predict surgical success defined as 50% reduction in apnea-hypopnea index (AHI) and AHI <10 events/hr post-surgery...
May 22, 2017: Sleep
https://www.readbyqxmd.com/read/28531332/are-sleep-problems-a-risk-factor-for-the-onset-of-musculoskeletal-pain-in-children-and-adolescents-a-systematic-review
#2
Alessandro Andreucci, Paul Campbell, Kate M Dunn
Study objectives: Musculoskeletal pain is a major burden on society. Adults with sleep problems are at higher risk for musculoskeletal pain onset, but there is no evidence for this relationship in children and adolescents. This study aimed to systematically review prospective studies on the risk for musculoskeletal pain onset in children and adolescents with sleep problems. Methods: Five databases (MEDLINE, PsycINFO, AMED, EMBASE, HMIC) were systematically searched to identify prospective studies that investigated if children and adolescents (aged 6-19 years) with sleep problems are at higher risk for musculoskeletal pain onset...
May 20, 2017: Sleep
https://www.readbyqxmd.com/read/28525646/sleep-during-menopausal-transition-a-six-year-follow-up
#3
Laura Lampio, Päivi Polo-Kantola, Sari-Leena Himanen, Samu Kurki, Eero Huupponen, Janne Engblom, Olli J Heinonen, Olli Polo, Tarja Saaresranta
Study Objectives: Menopausal transition is associated with increased dissatisfaction with sleep, but the effects on sleep architecture are conflicting. This prospective six-year follow-up study was designed to evaluate the changes in sleep stages and sleep continuity that occur in women during menopausal transition. Methods: Sixty women (mean age 46.0 years, SD 0.9) participated. All women were premenopausal at baseline, and at the six-year follow-up, women were in different stages of menopausal transition...
May 19, 2017: Sleep
https://www.readbyqxmd.com/read/28525637/characterizing-adult-sleep-behavior-over-20-years-the-population-based-doetinchem-cohort-study
#4
Margot L Zomers, Gerben Hulsegge, Sandra H van Oostrom, Karin I Proper, Wm Monique Verschuren, H Susan J Picavet
Study Objectives: To describe sleep duration patterns of adults over a 20-year period, to compare sociodemographic, lifestyle, and health characteristics across these patterns, and to relate the patterns to sleep quality. Methods: The study population consisted of 3,695 adults aged 20 to 59 years at baseline. Five measurements of self-reported sleep duration were used to compose seven patterns from 1987 to 2012: persistent short (≤6 hours), moderate (7-8 hours), or long (≥9 hours) sleep duration and several changing patterns (varying and became short, moderate, or long sleepers)...
May 19, 2017: Sleep
https://www.readbyqxmd.com/read/28525634/association-between-weekend-catch-up-sleep-and-lower-body-mass-population-based-study-weekend-catch-up-sleep-and-body-mass-index
#5
Hee-Jin Im, Shin-Hye Baek, Min Kyung Chu, Kwang Ik Yang, Won-Joo Kim, Seong-Ho Park, Robert J Thomas, Chang-Ho Yun
Study Objectives: To determine if weekend catch-up sleep (CUS) impacts body mass index (BMI) in the general population. Methods: A stratified random sample (2,156 subjects; age 19-82 years old, 43.0±14.5; 1,183 male) from the general population was evaluated, in 2010, using face-to-face interviews about sociodemographic characteristics, height, weight, habitual sleep duration and time-in-bed at night on weekdays and weekend, sleep-related profiles, mood and anxiety scales, and comorbid-medical conditions...
May 19, 2017: Sleep
https://www.readbyqxmd.com/read/28525628/modulation-of-the-muscle-activity-during-sleep-in-cervical-dystonia
#6
E Antelmi, R Ferri, F Provini, C Scaglione, F Mignani, F Rundo, S Vandi, M Fabbri, F Pizza, G Plazzi, P Martinelli, R Liguori
Introduction: Impaired sleep has been reported as an important non-motor feature in dystonia, but so far, subjective complaints have never been compared with nocturnal video-polysomnographic recording, which is the gold standard to assess sleep-related disorders. Methods: Twenty patients with idiopathic isolated cervical dystonia and 22 healthy controls underwent extensive clinical investigations, neurological examination and questionnaires screening for excessive daytime sleepiness and sleep-related disorders...
May 19, 2017: Sleep
https://www.readbyqxmd.com/read/28525617/what-sways-people-s-judgement-of-sleep-quality-a-quantitative-choice-making-study-with-good-and-poor-sleepers
#7
Fatanah Ramlee, Adam N Sanborn, Nicole K Y Tang
Study objectives: We conceptualised sleep quality judgement as a decision-making process and examined the relative importance of 17 parameters of sleep quality using a choice-based conjoint analysis. Methods: 100 participants (50 good sleepers; 50 poor sleepers) were asked to choose between two written scenarios to answer one of two questions: "Which describes a better (or worse) night of sleep?". Each scenario described a subjective experience of sleep, stringing together 17 possible determinants of sleep quality that occur at different times of the day (day before, pre-sleep, during sleep, upon waking, day after)...
May 19, 2017: Sleep
https://www.readbyqxmd.com/read/28521050/sudden-unexpected-death-during-sleep-in-familial-dysautonomia-a-case-control-study
#8
Jose-Alberto Palma, Lucy Norcliffe-Kaufmann, Miguel A Perez, Christy L Spalink, Horacio Kaufmann
Study Objectives: Sudden unexpected death during sleep (SUDS) is the most common cause of death in patients with familial dysautonomia, an autosomal recessive disease characterized by sensory and autonomic dysfunction. It remains unknown what causes SUDS in these patients and who is at highest risk. We tested the hypothesis that SUDS in FD is linked to sleep-disordered breathing. Methods: We retrospectively identified patients with familial dysautonomia who died suddenly and unexpectedly during sleep and had undergone polysomnography within the 18-month period prior to death...
May 18, 2017: Sleep
https://www.readbyqxmd.com/read/28482107/phasic-rem-transiently-approaches-wakefulness-in-the-human-cortex-a-single-pulse-electrical-stimulation-study
#9
Kiyohide Usami, Riki Matsumoto, Katsuya Kobayashi, Takefumi Hitomi, Masao Matsuhashi, Akihiro Shimotake, Takayuki Kikuchi, Kazumichi Yoshida, Takeharu Kunieda, Nobuhiro Mikuni, Susumu Miyamoto, Ryosuke Takahashi, Akio Ikeda
Study Objectives: To investigate the changes in cortical neural responses induced by external inputs during phasic rapid eye movement (REM) sleep. Methods: Single-pulse electrical stimulation (SPES) was directly applied to the human cortex during REM sleep through subdural electrodes, in seven patients who underwent invasive presurgical evaluation for intractable partial epilepsy. SPES was applied to parts of the cortex through the subdural electrodes, and induced cortical responses were recorded from adjacent and remote cortical areas...
May 8, 2017: Sleep
https://www.readbyqxmd.com/read/28482100/apoe-genotype-and-non-respiratory-sleep-parameters-in-cognitively-intact-older-adults
#10
Adam P Spira, Yang An, Yu Peng, Mark N Wu, Eleanor M Simonsick, Luigi Ferrucci, Susan M Resnick
Study Objectives: The apolipoprotein E (APOE) Ɛ4 allele increases Alzheimer's disease (AD) risk and has been linked to a greater risk of sleep-disordered breathing. We investigated the association of APOE genotype with non-respiratory sleep parameters. Methods: We studied 1,264 cognitively normal participants in the Baltimore Longitudinal Study of Aging (mean = 57.5±16.1 years, range 19.9-92.0, 48.2% women, 19.8% African American) with APOE genotyping and self-reported sleep duration (≥9, 7 or 8, ≤6 hours), difficulty falling/staying asleep, and napping...
May 6, 2017: Sleep
https://www.readbyqxmd.com/read/28482089/inter-episode-sleep-bruxism-intervals-and-myofascial-face-pain
#11
K Muzalev, F Lobbezoo, M N Janal, K G Raphael
Study Objectives: Sleep bruxism (SB) is considered as a possible etiological factor for Temporomandibular Disorder (TMD) pain. However, polysomnographic (PSG) studies, which are current "gold standard" diagnostic approach to SB, failed to prove an association between SB and TMD. A possible explanation could be that PSG studies have considered only limited characteristics of SB activity: the number of SB events per hour and, sometimes, the total duration of SB per night. According to the sports sciences literature, lack of adequate rest-time between muscle activities leads to muscle overloading and pain...
May 6, 2017: Sleep
https://www.readbyqxmd.com/read/28482056/rem-sleep-eeg-instability-in-rem-sleep-behavior-disorder-and-clonazepam-effects
#12
Raffaele Ferri, Francesco Rundo, Alessandro Silvani, Marco Zucconi, Oliviero Bruni, Luigi Ferini-Strambi, Giuseppe Plazzi, Mauro Manconi
Study Objectives: We aimed to analyze quantitatively REM sleep EEG in controls, drug-naïve idiopathic REM sleep behavior disorder patients (iRBD), and iRBD patients treated with clonazepam. Methods: Twenty-nine drug-naïve iRBD patients (mean age 68.2 years), 14 iRBD patients under chronic clonazepam therapy (mean age 66.3 years) and 21 controls (mean age 66.8 years) were recruited. Power spectra were obtained from sleep EEG (central derivation), using a 2-second sliding window, with 1-second steps...
May 6, 2017: Sleep
https://www.readbyqxmd.com/read/28482053/a-four-session-sleep-intervention-program-improves-sleep-for-older-adult-day-health-care-participants-results-of-a-randomized-controlled-trial
#13
Jennifer L Martin, Yeonsu Song, Jaime Hughes, Stella Jouldjian, Joseph M Dzierzewski, Constance H Fung, Juan Carlos Rodriguez Tapia, Michael N Mitchell, Cathy A Alessi
Study Objective: To test the effectiveness of a 4-week behavioral Sleep Intervention Program (SIP: sleep compression, modified stimulus control, and sleep hygiene) compared to a 4-week information-only control (IC) among older adults attending a VA Adult Day Health Care (ADHC) program in a double-blind, randomized, clinical trial. Methods: 42 individuals (mean age: 77 years, 93% male) enrolled in a VA ADHC program were randomized to receive SIP or IC. All completed in-person sleep and health assessments at baseline, post-treatment and 4-months follow-up that included 3 days/nights of wrist actigraphy, the Pittsburgh Sleep Quality Index (PSQI), and the Insomnia Severity Index (ISI)...
May 6, 2017: Sleep
https://www.readbyqxmd.com/read/28472528/internet-and-in-person-cognitive-behavioral-therapy-for-insomnia-in-military-personnel-a-randomized-clinical-trial
#14
Daniel J Taylor, Alan L Peterson, Kristi E Pruiksma, Stacey Young-McCaughan, Karin Nicholson, Jim Mintz
STUDY OBJECTIVES: Compare in-person and unguided Internet-delivered cognitive behavioral therapy for insomnia (CBTi) with a minimal contact control condition in military personnel. METHODS: A 3-arm parallel randomized clinical trial of 100 active duty US Army personnel at Fort Hood, Texas. Internet and in-person CBTi were comparable, except for the delivery format. The control condition consisted of phone call assessments. RESULTS: Internet and in-person CBTi both performed significantly better than the control condition on diary-assessed sleep efficiency (d = 0...
May 4, 2017: Sleep
https://www.readbyqxmd.com/read/28472425/prodromal-parkinsonism-and-neurodegenerative-risk-stratification-in-rem-sleep-behaviour-disorder
#15
Thomas R Barber, Michael Lawton, Michal Rolinski, Samuel Evetts, Fahd Baig, Claudio Ruffmann, Aimie Gornall, Johannes C Klein, Christine Lo, Gary Dennis, Oliver Bandmann, Timothy Quinnell, Zenobia Zaiwalla, Yoav Ben-Shlomo, Michele Tm Hu
Objectives.: REM sleep behaviour disorder (RBD) is the most specific marker of prodromal alpha-synucleinopathies. We sought to delineate the baseline clinical characteristics of RBD and evaluate risk stratification models. Methods.: Clinical assessments were performed in 171 RBD, 296 control and 119 untreated Parkinson's (PD) subjects. Putative risk measures were assessed as predictors of prodromal neurodegeneration and Movement Disorders Society (MDS) criteria for prodromal PD were applied...
May 4, 2017: Sleep
https://www.readbyqxmd.com/read/28472447/actigraphic-sleep-duration-and-fragmentation-in-older-women-associations-with-performance-across-cognitive-domains
#16
Adam P Spira, Katie L Stone, Susan Redline, Kristine E Ensrud, Sonia Ancoli-Israel, Jane A Cauley, Kristine Yaffe
Study Objectives: To determine the association of actigraphic sleep duration and fragmentation with cognition in community-dwelling older women. Methods: We studied 782 women (mean age = 87.4) of varied cognitive status from the Study of Osteoporotic Fractures who completed wrist actigraphy and the 3MS, California Verbal Learning Test-II-Short Form, digit span, verbal fluency tests, and the Trailmaking Test, Part B (Trails B). Total sleep time (TST) and wake after sleep onset (WASO) tertiles were our primary predictors...
May 2, 2017: Sleep
https://www.readbyqxmd.com/read/28472438/the-impact-of-chronic-sleep-restriction-on-neuronal-number-and-volumetric-correlates-of-the-dorsal-respiratory-nuclei-in-a-rat-model
#17
Ali-Mohammad Kamali, Fatemeh Karimi, Saied Karbalay-Doust, Mohammad Nami, Ali Noorafshan
Study Objectives: Sleep restriction can result in a range of neurophysiological consequences in the brain including some brain stem nuclei. This study aimed to evaluate the effects of chronic sleep restriction (CSR) on quantitative aspects of brain stem respiratory centers using stereological methods. Methods: Male rats were randomly assigned into experimental group (CSR through a modified multiple platform apparatus), corresponding apparatus-control group (grid-floor control) and cage controls...
May 2, 2017: Sleep
https://www.readbyqxmd.com/read/28460124/mild-traumatic-brain-injury-chronically-impairs-sleep-and-wake-dependent-emotional-processing
#18
Janna Mantua, Owen S Henry, Nolan F Garskovas, Rebecca M C Spencer
A single traumatic brain injury (TBI), even when mild (i.e., concussion), can cause lasting consequences. Individuals with a history of chronic (> 1 year prior) mild TBI have an increased risk of mood disturbances (e.g., depression, suicide). This population also has lingering sleep alterations, including poor sleep quality and changes in sleep stage proportions. Given these sleep deficits, we aimed to test whether sleep-dependent emotional memory consolidation is reduced in this population. We utilized a mild TBI group (3...
April 29, 2017: Sleep
https://www.readbyqxmd.com/read/28453783/sleep-related-breathing-disorders-in-chiari-malformation-type-1-a-prospective-study-of-90-patients
#19
Álex Ferré, Maria A Poca, Maria D de la Calzada, Dulce Moncho, Odile Romero, Gabriel Sampol, Juan Sahuquillo
Study objective: The aim of the present study is to describe the prevalence of sleep disorders in a large group of patients with Chiari malformation type 1 (CM-1) and determine the presence of risk factors associated with these abnormalities. Methods: Prospective study with consecutive patient selection. We included 90 adult patients with CM-1, defined by the presence of a cerebellar tonsillar descent (TD) ≥3mm. Clinical, neuroradiological studies and nocturnal polysomnography (PSG) was carried out...
April 27, 2017: Sleep
https://www.readbyqxmd.com/read/28444394/tissue-specific-dissociation-of-diurnal-transcriptome-rhythms-during-sleep-restriction-in-mice
#20
Jana Husse, Jana-Thabea Kiehn, Johanna L Barclay, Nadine Naujokat, Judit Meyer-Kovac, Hendrik Lehnert, Henrik Oster
Study objectives: Shortened or mistimed sleep affects metabolic homeostasis, which may in part be mediated by dysregulation of endogenous circadian clocks. In this study, we assessed the contribution of sleep disruption to metabolic dysregulation by analysing diurnal transcriptome regulation in metabolic tissues of mice subjected to a sleep restriction paradigm. Methods: Male mice were subjected to 2x5 days of sleep restriction (SR) with enforced waking during the first six hours of the light phase...
April 24, 2017: Sleep
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