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Tuo-Yu Chen, Soomi Lee, Margeaux M Schade, Yasuhiko Saito, Angelique Chan, Orfeu M Buxton
The association of sleep with pain is well documented among adult populations. Even though both sleep problems and pain are prevalent in older adults, the longitudinal and bidirectional relationship between sleep deficiency (i.e., insufficient and poor sleep) and pain is less well established. This study investigated the association between sleep deficiency and pain among community-dwelling adults aged 65 years and older across a 2-3 year period. We analyzed cross-country data from the Nihon University Japanese Longitudinal Study of Aging (N = 2888) and the Panel on Health and Aging of Singaporean Elderly (N = 2111)...
November 12, 2018: Sleep
Amy R Goetz, Dean W Beebe, James L Peugh, Constance A Mara, Bruce P Lanphear, Joseph M Braun, Kimberly Yolton, Lori J Stark
Study Objectives: High birth weight (HBW; ≥ 4000g) is strongly associated with later overweight, yet little is known about how to disrupt this trajectory. The current study examined sleep practices during infancy and toddlerhood among children born HBW or normal birth weight (NBW; 2500-3999g). Methods: Latent growth curve models were used to examine sleep during infancy and toddlerhood among 270 mother-child dyads enrolled in the Health Outcomes and Measures of the Environment Study...
November 9, 2018: Sleep
Brian J Miller, Carmen B Parker, Mark H Rapaport, Peter F Buckley, William V McCall
Study Objectives: Insomnia is a common symptom in the clinical course of schizophrenia. There is a robust association between insomnia and suicidality in other psychiatric disorders. Two previous studies found associations between insomnia and suicide attempt or completed suicide in patients with schizophrenia. We hypothesized that greater insomnia would be associated with greater levels of suicidal ideation in patients with schizophrenia and other non-affective psychoses. Method: We recruited 108 inpatients and outpatients age 18-65 between July 2010 and July 2016 with DSM-IV non-affective psychosis (schizophrenia, schizoaffective disorder, or schizophreniform disorder)...
November 8, 2018: Sleep
Olivier Mairesse, Eoin Macdonald-Nethercott, Daniel Neu, Helio Fernandez Tellez, Emilie Dessy, Xavier Neyt, Romain Meeusen, Nathalie Pattyn
Study Objectives: Manned spaceflights from Earth to Mars will likely become reality within the next decades. Humans will be exposed to prolonged isolation, confinement, and altered photoperiods in artificial atmospheric conditions, with potential adverse effects on sleep and performance. On Earth, polar environments serve as space-analogues to study human adaptation, yet few studies include polysomnography due to operational constraints. Methods: Polysomnography, subjective sleepiness and fatigue and psychomotor performance were measured every six weeks in 13 males ("Hivernauts") during a 13-month winter-over campaign at Concordia (Antarctica)...
November 7, 2018: Sleep
Asher Y Rosinger, Anne-Marie Chang, Orfeu Buxton, Junjuan Li, Shouling Wu, Xiang Gao
Study Objectives: Short and long sleep duration are linked to reduced kidney function, but little research has examined how sleep is associated with hydration status. Our aim was to assess the relationship between sleep duration and urinary hydration biomarkers among adults in a cross-cultural context. Methods: Three samples of adults aged 20y were analyzed: 2007-2008 National Health and Nutrition Examination Survey (NHANES; n=4,680), 2009-2012 NHANES (n=9,559), and 2012 cross-sectional wave of the Chinese Kailuan Study (n=11,903), excluding pregnant women and adults with failing kidneys...
November 5, 2018: Sleep
Nicole G Nahmod, Soomi Lee, Lindsay Master, Anne-Marie Chang, Lauren Hale, Orfeu M Buxton
Study Objectives: High school start times (SSTs) directly impact adolescents' sleep timing and duration. This study investigated the associations between SSTs and actigraphically-measured 24-hour sleep duration, sleep onset, sleep offset and sleep quality. Methods: This study included 383 adolescents (Mage=15.5, SDage=0.6 years) participating in the age 15 wave of the Fragile Families & Child Wellbeing Study, a national birth cohort study sampling from 20 large U...
November 3, 2018: Sleep
Shuai Liu, Yun Kwok Wing, Yanli Hao, Weixia Li, Jihui Zhang, Bin Zhang
Study Objectives: To determine the longitudinal associations of long-time mobile phone use (LTMPU) with sleep disturbances and mental distress in a prospective cohort of technical college students. Methods: A total of 4,333 (response rate: 91.5%) and 3,396 (response rate: 78.4%) participants were recruited at baseline and eight-month follow-up, respectively. Data were collected by a set of questionnaires including socio-demographics, lifestyle practice, duration of mobile phone use per day, sleep patterns on weekdays and weekends, as well as Insomnia Severity Index, Epworth Sleepiness Scale, reduced Morningness-Eveningness Questionnaire, Beck Depression Inventory, and Zung Self-Rating Anxiety Scale...
November 3, 2018: Sleep
James N Cousins, Kian F Wong, Bindiya L Raghunath, Carol Look, Michael W L Chee
Study objectives: Daytime naps benefit long-term memory relative to taking a break and remaining awake. However, the use of naps as a practical way to improve learning has not been examined, in particular, how memory following a nap compares with spending the equivalent amount of time cramming. Methods: Young adults learned detailed factual knowledge in sessions that flanked one-hour spent napping (n=27), taking a break (n=27), or cramming that information (n=30)...
October 29, 2018: Sleep
Akane Kohno, Yuji Kitamura, Shinichiro Kato, Hirohisa Imai, Yoshitada Masuda, Yasunori Sato, Shiroh Isono
Study Objectives: Animal studies suggest a pivotal role of the hyoid bone in obstructive sleep apnea (OSA). We aimed to explore the role of the hyoid bone in humans by testing the hypotheses that muscle paralysis and lung volume (LV) changes displace the hyoid bone position particularly in patients with obesity and/or OSA. Methods: Fifty patients undergoing general anesthesia participated in this study (20 non-obese, non-OSA subjects; 8 non-obese patients with OSA; 22 obese OSA patients)...
October 29, 2018: Sleep
Michael T Smith, Bethany Remeniuk, Patrick H Finan, Traci J Speed, D Andrew Tompkins, Mercedes Robinson, Kaylin Gonzalez, Martin F Bjurstrom, Michael R Irwin
Objectives: Females demonstrate heightened central sensitization (CS), a risk factor for chronic pain characterized by enhanced responsivity of central nervous system nociceptors to normal or subthreshold input. Sleep disruption increases pain sensitivity, but sex has rarely been evaluated as a moderator and few experiments have measured CS. We evaluated whether two nights of sleep disruption alters CS measures of secondary hyperalgesia and mechanical temporal summation in a sex dependent manner...
October 29, 2018: Sleep
John H Harkness, Priyanka N Bushana, Ryan P Todd, William C Clegern, Barbara A Sorg, Jonathan P Wisor
We used a novel automated sleep disruption (SD) apparatus to determine the impact of SD on sleep and molecular markers of oxidative stress in parvalbumin (PV) neurons in the rat prefrontal cortex (PFC). Rats were subjected to two 6-hr SD sessions from zeitgeber time (ZT) 0 to ZT6, once by the gentle handling method and the other by an automated agitator running the length of the rat's home cage floor (a novel SD method). The same rats were later subjected to a 12-hr SD session from ZT0 - ZT12. Sleep was disrupted with both methods, although rats slept less during gentle handling than during the automated condition...
October 27, 2018: Sleep
R Glenn Weaver, Michael W Beets, Michelle Perry, Ethan Hunt, Keith Brazendale, Lindsay Decker, Gabrielle Turner-McGrievy, Russell Pate, Shawn D Youngstedt, Brian E Saelens, Alberto Maydeu-Olivares
Study Objectives: To examine changes in elementary aged children's sleep and physical activity during a one-week and a three-week school break. Methods: Sleep and physical activity of elementary children (n=154, age=5-9 years, 44.8% female, 65.5% African American) were collected over seven weeks that included a one-week break in two schools and a three-week break in a single school. Mixed regression models estimated sleep and physical activity changes within and between groups (i...
October 24, 2018: Sleep
Johan Skoog, Helena Jönsson, Robert Sigström, Svante Östling, Hanna Falk, Margda Waern, Valgeir Thorvaldsson, Ingmar Skoog, Boo Johansson
Study objectives: To investigate birth cohort differences in the prevalence of insomnia from age 70 to 79. Methods: Data were drawn from populations-based samples of two cohorts of septuagenarians; the early born 1901-07-cohort, who took part in psychiatric examinations between 1971-1986 (n=681), and the later born 1930-cohort, examined between 2000-2010 (n=943). Examinations were conducted at ages 70, 75 and 79. Criteria for insomnia were identical across cohorts and included sleep dissatisfaction accompanied with complaints of difficulty initiating or maintaining sleep...
October 24, 2018: Sleep
Teng-Teng Fan, Wen-Hao Chen, Le Shi, Xiao Lin, Serik Tabarak, Si-Jing Chen, Jian-Yu Que, Yan-Ping Bao, Xiang-Dong Tang, Jie Shi, Lin Lu, Hong-Qiang Sun, Jia Jia Liu
Study Objectives: Objective sleep duration has been linked to insomnia severity. However, cognitive functions of insomniacs with different sleep duration have been seldom addressed. Brain-derived neurotrophic factor (BDNF) has an important role in cognitive function and has been linked to clinical insomnia recently. The present study aimed to evaluate the comprehensive cognitive functions in primary insomniacs with different objective sleep durations, and further examine the involvement of peripheral BDNF...
October 22, 2018: Sleep
Michelle Reid, Janice E Maras, Steven Shea, Alexis C Wood, Cecilia Castro-Diehl, Dayna A Johnson, Tianyi Huang, David R Jacobs, Allison Crawford, Marie-Pierre St-Onge, Susan Redline
Rationale: While short sleep duration has been linked to unhealthy dietary patterns, little is known about the association of obstructive sleep apnea (OSA), a disorder characterized by sleep fragmentation, and diet. Objective: Investigate associations between diet quality and OSA in the Multi-Ethnic Study of Atherosclerosis and assess whether reductions in slow wave sleep (stage N3) and rapid eye movement (REM) sleep are potential mediators for these associations...
October 22, 2018: Sleep
Jessica E Owen, Bryndis Benediktsdottir, Thorarinn Gislason, Stephen R Robinson
Obstructive sleep apnea (OSA) is commonly associated with memory impairments. Although MRI studies have found volumetric differences in the hippocampus of OSA patients compared to controls, MRI lacks the spatial resolution to detect changes in the specific regions of the hippocampus that process different types of memory. The present study performed histopathological investigations on autopsy brain tissue from 32 OSA patients (17 female, 15 male) to examine whether the thickness and myelination of the hippocampus and entorhinal cortex (EC) vary as a function of OSA severity...
October 20, 2018: Sleep
B Stojanoski, A Benoit, N Van Den Berg, L B Ray, A M Owen, A Shahidi Zandi, A Quddus, F J E Comeau, S M Fogel
Study Objectives: The behavioural and cognitive consequences of severe sleep deprivation are well understood. Surprisingly, relatively little is known about the neural correlates of mild and acute sleep restriction on tasks that require sustained vigilance for prolonged periods of time during the day. Methods and Results: Event-related potential (ERP) paradigms can reveal insight into the neural correlates underlying visual processing and behavioral responding that is impaired with reduced alertness, as a consequence of sleep loss...
October 20, 2018: Sleep
Paola Malerba, Lauren N Whitehurst, Stephen B Simons, Sara C Mednick
Electrophysiological sleep rhythms have been shown to impact human waking cognition, but their spatio-temporal dynamics are not understood. We investigated how slow oscillations (SOs, 0.5-4 Hz) are organized during a night of polysomnographically-recorded sleep, focusing on the scalp electrode manifold. We detected troughs of SOs at all electrodes independently and analyzed the concurrent SO troughs found in every other electrode within ±400ms. We used a k-clustering algorithm to categorize the spatial patterns of SO trough co-occurrence into three types (Global, Local or Frontal) depending on their footprint on the electrode manifold during the considered time window...
October 17, 2018: Sleep
Lisa J Meltzer, Michelle Short, Genery D Booster, Michael Gradisar, Christine A Marco, Amy R Wolfson, Mary A Carskadon
Study Objectives: Provide actigraphic reference values for motor activity during sleep for children and adolescents ages 8-17 years. Methods: Participants were 671 healthy community-dwelling children and adolescents (52% female, mean age 13.5+2.4 years) from the United States (64%) and Australia (36%). All participants wore an Ambulatory-Monitoring Inc. (AMI, Ardsley, NY) actigraph on their non-dominant wrist for ≥5 nights and completed daily sleep diaries. Actigraphy data were scored with standard methods and a validated algorithm...
October 17, 2018: Sleep
Shahrokh Javaheri, Scott W McKane, Nathan Cameron, Robin E Germany, Atul Malhotra
Study Objectives: Periodic breathing with central sleep apnea (CSA) is common in patients with left ventricular systolic dysfunction. Based on the pathophysiological mechanisms underlying CSA, we hypothesized that the frequency of CSA episodes would increase in the late hours of non-rapid eye movement (NREM) of sleep. Methods: Forty-one patients with left ventricular ejection fraction <40% underwent full-night-attended polysomnography scored by a central core lab...
October 16, 2018: Sleep
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