journal
MENU ▼
Read by QxMD icon Read
search

Transplant International: Official Journal of the European Society for Organ Transplantation

journal
https://www.readbyqxmd.com/read/28700114/increasing-incidence-of-melanoma%C3%A2-after-solid-organ-transplantation-a-retrospective-epidemiological-study
#1
Kinda Fattouh, Emilie Ducroux, Evelyne Decullier, Jean Kanitakis, Emmanuel Morelon, Pascale Boissonnat, Laurent Sebbag, Denis Jullien, Sylvie Euvrard
BACKGROUND: The risk of melanoma in organ transplant recipients (OTR) is increased compared with the general population. METHODS: This retrospective study registered all cases of post-transplant melanoma in kidney, heart, lung and liver transplant recipients followed in our specialized post-transplant Dermatology clinic since 1991. The yearly prevalence of melanoma and skin carcinoma between 2000 and 2015 were computed and compared in this population. Based on another cohort of kidney transplant recipients grafted since 2005, adjusted age- and sex- standardized incidence ratio (SIR) was calculated using a renal transplantation registry...
July 12, 2017: Transplant International: Official Journal of the European Society for Organ Transplantation
https://www.readbyqxmd.com/read/28691253/cardiovascular-disease-risk-in-patients-receiving-organ-transplantation-a-national-cohort-study
#2
Hsin-I Tsai, Fu-Chao Liu, Chao-Wei Lee, Chang-Fu Kuo, Lai-Chu See, Ting-Ting Chung, Huang-Ping Yu
Although organ transplantation is the definitive treatment for end stage organ failure, the post-transplant outcomes can be substantially influenced by cardiovascular complications. A national cohort study was performed to estimate risks of cardiovascular diseases in those with heart, lung, kidney and liver transplantation. This cohort study consisted of 5,978 solid organ transplantations identified using the Taiwan National Health Insurance Database. Cardiovascular and mortality risks in transplant recipients were evaluated using standardized incidence ratios, excess absolute risks, and standardized mortality ratios as compared to those in the general population...
July 10, 2017: Transplant International: Official Journal of the European Society for Organ Transplantation
https://www.readbyqxmd.com/read/28686316/is-pre-transplant-sensitization-against-angiotensin-ii-type1-receptor-still-a-risk-factor-of-graft-and-patient-outcome-in-kidney-transplantation-in-the-anti-hla-luminex-era
#3
C Deltombe, F Gillaizeau, D Anglicheau, E Morelon, K Trébern-Launay, F Le Borgne, M Rimbert, P Guérif, S Malard-Castagnet, Y Foucher, M Giral
AIMS: We aimed to assess the correlation of anti-angiotensin II type 1 receptor antibodies (anti-AT1R-Abs) before transplantation on a multicentric cohort of kidney transplant recipients (2008-2012), under Tacrolimus and Mycofenolate mofetil (MMF), screened by Luminex technology for anti -HLA immunization. METHODS: Anti-AT1R-antibody levels were measured by ELISA in pre-transplantation sera of 940 kidney recipients from 3 French centers of the DIVAT cohort. Multivariable Cox models estimated the association between pre-transplant anti-angiotensin II type 1 receptor antibodies and time to acute rejection episodes (ARE) or time to graft failure...
July 7, 2017: Transplant International: Official Journal of the European Society for Organ Transplantation
https://www.readbyqxmd.com/read/28686307/characteristics-of-liver-transplant-candidates-delisted-following-recompensation-and-predictors-of-such-delisting-in-alcohol-related-liver-disease-a-case-control-study
#4
Authors Aloysious D Aravinthan, Andrew S Barbas, Adam C Doyle, Mahmood Tazari, Gonzalo Sapisochin, Mark S Cattral, Anand Ghanekar, Ian D McGilvray, Markus Selzner, Paul D Greig, Mamatha Bhat, Nazia Selzner, David R Grant, Leslie B Lilly, Eberhard L Renner
Whether and when recovery beyond the need for transplant may occur in patients listed for decompensation remains unclear. This study aimed to investigate the characteristics of patients delisted following recompensation. Seventy-seven patients who were listed between 2005 and 2015 for decompensation, but later delisted following recompensation were included. Alcohol-related liver disease (ALD) was the underlying etiology in the majority (n=47, 61%). Listing characteristics of these patients were compared with those of decompensated ALD patients who either underwent deceased donor liver transplantation or died on the waiting list...
July 7, 2017: Transplant International: Official Journal of the European Society for Organ Transplantation
https://www.readbyqxmd.com/read/28672081/concurrent-biopsies-of-both-grafts-in-recipients-of-simultaneous-pancreas-and-kidney-demonstrates-high-rates-of-discordance-for-rejection-as-well-as-discordance-in-type-of-rejection
#5
Sandesh Parajuli, Emre Arpali, Brad C Astor, Arjang Djamali, Fahad Aziz, Robert R Redfield, Hans W Sollinger, Dixon Kaufman, Jon Odorico, Didier Mandelbrot
It is commonly assumed that in simultaneous kidney and pancreas (SPK) recipients, rejection of the two organs is concordant. As a result, concurrent biopsies of both organs are rarely performed and there are limited histological data on how often rejection is in fact discordant. We reviewed all SPK recipients transplanted at the University of Wisconsin between 01/01/2001 and 12/31/2016 that underwent biopsy of both organs. We included all patients whose biopsies were within 30 days. If patients were treated for rejection between biopsies, they were excluded if the biopsies were more than 4 days apart...
July 3, 2017: Transplant International: Official Journal of the European Society for Organ Transplantation
https://www.readbyqxmd.com/read/28672061/thalidomide-treatment-prevents-chronic-graft-rejection-after-aortic-transplantation-in-rats
#6
Katharine K Miller, Dong Wang, Xiaomeng Hu, Xiaoqin Hua, Tobias Deuse, Evgenios Neofytou, Thomas Renne, Joachim Velden, Hermann Reichenspurner, Sonja Schrepfer, Daniel Bernstein
BACKGROUND: Cardiac allograft vasculopathy (CAV) affects approximately 30% of cardiac transplant patients at five years post-transplantation. To date there are few CAV treatment or prevention options, none of which are highly effective. The aim of the study was to investigate the effect of thalidomide on the development of CAV. METHODS: The effect of thalidomide treatment on chronic rejection was assessed in rat orthotopic aortic transplants in allogeneic F344 or syngeneic Lew rats (n=6/group)...
July 3, 2017: Transplant International: Official Journal of the European Society for Organ Transplantation
https://www.readbyqxmd.com/read/28672056/surgical-complications-of-laparoendoscopic-single-site-donor-nephrectomy-a-retrospective-study
#7
John C LaMattina, Jessica M Powell, Nadiesda A Costa, David B Leeser, Silke V Niederhaus, Jonathan S Bromberg, Josue Alvarez-Casas, Michael S Phelan, Rolf N Barth
The single-port approach has been associated with an unacceptably high rate of umbilical port hernias in large series of patients undergoing single-port cholecystectomy and colectomy and with additional surgical risks thought secondary to technical and ergonomic limitations. A retrospective review of 378 consecutive laparoendoscopic single-site(LESS) donor nephrectomies performed between 04/15/2009 and 04/09/2014 was conducted. Twelve patients (3%) developed an umbilical hernia. Eleven (92%) were female and eight (73%) of these patients had a prior pregnancy...
July 3, 2017: Transplant International: Official Journal of the European Society for Organ Transplantation
https://www.readbyqxmd.com/read/28667778/organ-donation-following-euthanasia-starting-at-home
#8
LETTER
Johannes Mulder, Johan P C Sonneveld
No abstract text is available yet for this article.
July 1, 2017: Transplant International: Official Journal of the European Society for Organ Transplantation
https://www.readbyqxmd.com/read/28667664/tacrolimus-and-mycophenolate-regimen-and-subclinical-tubulo-interstitial-inflammation-in-low-immunological-risk-renal-transplants
#9
Irina B Torres, Anna V Reisaeter, Francesc Moreso, Anders Âsberg, Marta Vidal, Clara Garcia-Carro, Karsten Midtvedt, Finn P Reinholt, Helge Scott, Eva Castellà, Maite Salcedo, Christina Dörje, Joana Sellarés, Maria A Azancot, Manel Perello, Hallvard Holdaas, Daniel Serón
The aim was to evaluate the relationship between maintenance immunosuppression, subclinical tubulo-interstitial inflammation and interstitial fibrosis/tubular atrophy (IF/TA) in surveillance biopsies performed in low immunological risk renal transplants at two transplant centers. The Barcelona cohort consisted of 109 early and 66 late biopsies in patients receiving high tacrolimus (TAC-C0 target at 1-year 6-10 ng/ml) and reduced MMF dose (500 mg bid at 1-year). The Oslo cohort consisted of 262 early and 237 late biopsies performed in patients treated with low TAC-C0 (target 3-7 ng/ml) and standard MMF dose (750 mg bid)...
July 1, 2017: Transplant International: Official Journal of the European Society for Organ Transplantation
https://www.readbyqxmd.com/read/28622441/cardiovascular-mortality-among-liver-transplant-recipients-with-nonalcoholic-steatohepatitis-nash-in-the-united-states
#10
Sanjaya K Satapathy, Yu Jiang, James D Eason, Satish K Kedia, Emily Wong, Ashwani K Singal, Elizabeth A Tolley, Donna Hathaway, Satheesh Nair, Jason M Vanatta
Nonalcoholic Steatohepatitis (NASH) has become an increasingly important indication for liver transplantation (LT), and there has been a particular concern of excessive cardiovascular-related mortality in this group METHODS: Using the United Network for Organ Sharing-Standard Transplant Analysis and Research (UNOS-STAR) dataset, we reviewed data on 56,995 adult transplants (January 2002 through June 2013). 3,170 NASH liver-only recipients were identified and were matched with 3,012 non-NASH HCV+ and 3,159 non-NASH HCV- controls [matched 1:1 based on gender, age at LT (±3 years), and MELD score (±3)] RESULTS: Cox regression analysis revealed significantly lower hazard of all-cause (HR 0...
June 16, 2017: Transplant International: Official Journal of the European Society for Organ Transplantation
https://www.readbyqxmd.com/read/28608627/all-s-well-following-living-kidney-donation
#11
John Scandling
Wellbeing following living kidney donation, both physical and psychosocial, continues to be a concern and area of investigative focus decades following the acceptance of kidney transplantation as treatment for end-stage kidney disease. In this issue, Maple and colleagues report their prospective study of wellbeing in living kidney donors during the first year after donation, using a comprehensive array of psychosocial outcome measures. Their aim was to produce a quantitative analysis to better inform both transplant teams and potential donors...
June 13, 2017: Transplant International: Official Journal of the European Society for Organ Transplantation
https://www.readbyqxmd.com/read/28608619/efficacy-and-safety-of-daclatasvir-based-antiviral-therapy-in-hcv-recurrence-after-liver-transplantation-role-of-cirrhosis-and-genotype-3-a-multi-centre-cohort-study
#12
Magdalena Salcedo, Martín Prieto, Lluís Castells, Juan Manuel Pascasio, Jose Luis Montero Alvarez, Inmaculada Fernández, Gloria Sánchez-Antolín, Luisa González-Diéguez, Miguel García-Gonzalez, Alejandra Otero, Sara Lorente, Maria Dolores Espinosa, Milagros Testillano, Antonio González, Jose Castellote, Fernando Casafont, Maria-Carlota Londoño, Jose Antonio Pons, Esther Molina Pérez, Valentín Cuervas-Mons, Sonia Pascual, Jose Ignacio Herrero, Isidoro Narváez, Carmen Vinaixa, Jordi Llaneras, Jose Manuel Sousa, Rafael Bañares
BACKGROUND & AIMS: Direct-acting antiviral agents (DAA) combining daclatasvir (DCV) have reported good outcomes in the recurrence of hepatitis C virus (HCV) infection after liver transplant (LT). However, its effect on the severe recurrence and the risk of death remains controversial. We evaluated the efficacy, predictors of survival, and safety of DAC-based regimens in a large real-world cohort. METHODS: A total of 331 patients received DCV-based therapy. Duration of therapy and ribavirin use were at the investigator's discretion...
June 13, 2017: Transplant International: Official Journal of the European Society for Organ Transplantation
https://www.readbyqxmd.com/read/28608574/the-attitude-of-latin-american-immigrants-in-florida-usa-towards-deceased-organ-donation
#13
Antonio Ríos, Ana Isabel López-Navas, José Antonio García, Gregorio Garrido, Marco Antonio Ayala-García, María José Sebastián, Antonio Miguel Hernandez, Pablo Ramírez, Pascual Parrilla
INTRODUCTION: The Latin American (LA) population resident in the USA is a growing subgroup of the population. OBJECTIVE: To find out the structure of attitude towards organ donation in the LA population resident in Florida (USA). METHODS: A sample was taken of LA residents in Florida, randomised and stratified by nationality, age and sex (n=1524). Attitude was assessed using a validated questionnaire (PCID-DTO Rios), that was self-completed anonymously...
June 13, 2017: Transplant International: Official Journal of the European Society for Organ Transplantation
https://www.readbyqxmd.com/read/28605573/prediction-of-biliary-anastomotic-stricture-after-deceased-donor-liver-transplantation-the-impact-of-platelet-counts
#14
Kazuhiro Takahashi, Shunji Nagai, Krishna G Puchakayala, Mohamed Safwan, Masahiko Gosho, Amy Y Li, William J Kane, Priyanka L Singh, Michael D Rizzari, Kelly M Collins, Atsushi Yoshida, Marwan S Abouljoud, Gabriel T Schnickel
Biliary stricture is a common cause of morbidity after liver transplantation (LT). This study aimed to determine the risk factors for post-transplant biliary anastomotic strictures (BAS), focusing on perioperative platelet counts. We enrolled 771 consecutive recipients who underwent ABO-identical/compatible deceased donor LT with duct-to-duct biliary reconstruction from January 2000 to June 2012. BAS was identified in 142 cases. The median time for stricture development was 176 days. Preoperative and postoperative platelet counts within 5 days after LT were significantly lower in patients with BAS than those without BAS...
June 12, 2017: Transplant International: Official Journal of the European Society for Organ Transplantation
https://www.readbyqxmd.com/read/28590558/tangential-extraperitoneal-retrorenal-ter-approach-a-specified-uniform-technique-for-renal-transplant-biopsy
#15
LETTER
Miro Dominik Boban, Martin Tiefenthaler
while rarely discussed in literature, we want to draw attention to the fact that the risk for complications induced by percutaneous renal transplant biopsy (PRTB) might depend on the topography of the chosen biopsy path. Only a few possible techniques and approaches have been adequately described by now. In 2010, Patel et al. indicated substantial advantages of various tangential biopsy approaches [1]. Still, their study reported cases of transfusion-requiring bleedings, intraperitoneal hemorrhage and rectus sheath hematoma...
June 7, 2017: Transplant International: Official Journal of the European Society for Organ Transplantation
https://www.readbyqxmd.com/read/28585408/increased-risk-of-infection-associated-death-with-incompatible-kidney-transplantations
#16
Christian Morath, Martin Zeier, Caner Süsal
In times of organ shortage, transplantation over the blood group A/B and HLA antibody barriers helps increasing the living donor pool in kidney transplantation. Waiting times are reduced while patient survival may be improved. By desensitization, both blood group A/B as well as HLA antibodies are eliminated from the patient's circulation using plasmapheresis, double filtration plasmapheresis or selective or unselective immunoadsorption. In addition, antibody production and posttransplant antibody rebound are prevented by powerful immunosuppression and induction therapy with or without B-cell eliminating anti-CD20 antibody rituximab...
June 6, 2017: Transplant International: Official Journal of the European Society for Organ Transplantation
https://www.readbyqxmd.com/read/28574620/rescue-allocation-and-recipient-oriented-extended-allocation-in-kidney-transplantation-influence-of-the-eurotransplant-allocation-system-on-recipient-selection-and-graft-survival-for-initially-non-accepted-organs
#17
Roger Wahba, Barbara Suwelack, Wolfgang Arns, Figen Cakiroglu, Ute Eisenberger, Thorsten Feldkamp, Anita Hansen, Kathrin Ivens, Thomas Klein, Andreas Kribben, Christine Kurschat, Ulrich Lange, Anja Mühlfeld, Martin Nitschke, Stefan Reuter, Kevin Schulte, Richard Viebahn, Rainer Woitas, Martin Hellmich, Dirk L Stippel
Non-accepted kidneys grafts enter the rescue allocation (RA) process to avoid discards. In December 2013 recipient oriented extended allocation (REAL) was introduced to improve transparency. Aim of this study was to evaluate the influence of REAL on recipients' selection and graft function compared to the formerly existing RA as well as to identify factors that influence graft outcome. Therefore, a multicenter study of 10 transplant centers in the same region in Germany was performed. All transplantations after RA or REAL from 1st December 2012 until 31st December 2014 with a follow-up time until 31st December 2015 were analyzed...
June 2, 2017: Transplant International: Official Journal of the European Society for Organ Transplantation
https://www.readbyqxmd.com/read/28556989/weight-based-dosing-of-alemtuzumab-an-ounce-of-prevention
#18
Joshua J Augustine
Alemtuzumab is a lymphocyte-depleting humanized monoclonal antibody that targets CD52 and binds to T and B lymphocytes, macrophages, monocytes and natural killer cells.(1) It was approved decades ago for the treatment of B-cell chronic lymphocytic leukemia (CLL), and the use of alemtuzumab in kidney transplantation was first described in the late 1990s as a drug that could promote tolerance and allow for maintenance drug minimization.(2) Although there has been variability in dosing in renal transplantation(3-5) , alemtuzumab is typically administered at a dosage of 30 mg intravenously once or twice in the perioperative transplant period, which is a fraction the cumulative dosage used for CLL...
May 30, 2017: Transplant International: Official Journal of the European Society for Organ Transplantation
https://www.readbyqxmd.com/read/28556538/a-retrospective-database-analysis-to-evaluate-the-potential-of-evlp-to-recruit-declined-lung-donors
#19
An Martens, Dirk E Van Raemdonck, Jacqueline Smits, Stijn E Verleden, Robin Vos, Bart M Vanaudenaerde, Geert M Verleden, Karlien Degezelle, Bruno Desschans, Arne P Neyrinck
BACKGROUND: Ex-vivo lung perfusion (EVLP) is currently used for both standard and extended-criteria donor (ECD) lungs. To enlarge the donor pool, we might have to extend the threshold for ECD donation. The purpose of this study was to estimate how many additional ECD lungs could be recruited by EVLP. METHODS: We reviewed all multi-organ donors (MODs) from our collaborative donor hospitals (January 2010 - June 2015). All unused lung donors, were categorized using registered donor data and evaluated by two independent investigators to identify which lungs could be transplanted after EVLP...
May 27, 2017: Transplant International: Official Journal of the European Society for Organ Transplantation
https://www.readbyqxmd.com/read/28556488/induction-therapy-with-rabbit-antithymocyte-globulin-versus-basiliximab-after-kidney-transplantation-a-health-economic-analysis-from-a-german-perspective
#20
Liana Cremaschi, Regina von Versen, Thomas Benzing, Michael Wiesener, Nikolai Zink, Gary Milkovich, Thomas Paivanas, Meghan Gallagher, Friedrich Thaiss
A health economic analysis was undertaken based on the one-year database from a randomized study of rabbit anti-human thymocyte immunoglobulin (rATG) versus basiliximab, in kidney transplantation using resource utilization data and cost estimates from three German hospitals. A three-state Markov model was applied to estimate cost effectiveness to 10 years post-transplant. Total mean treatment cost per patient to year 1 post-transplant was €62,075 versus €59,767 for rATG versus basiliximab (p<0.01). rATG therapy was associated with similar treatment costs to basiliximab by year 2, and a predicted cumulative treatment cost saving of €4,259 under rATG versus basiliximab by year 10 post-transplant...
May 27, 2017: Transplant International: Official Journal of the European Society for Organ Transplantation
journal
journal
20283
1
2
Fetch more papers »
Fetching more papers... Fetching...
Read by QxMD. Sign in or create an account to discover new knowledge that matter to you.
Remove bar
Read by QxMD icon Read
×

Search Tips

Use Boolean operators: AND/OR

diabetic AND foot
diabetes OR diabetic

Exclude a word using the 'minus' sign

Virchow -triad

Use Parentheses

water AND (cup OR glass)

Add an asterisk (*) at end of a word to include word stems

Neuro* will search for Neurology, Neuroscientist, Neurological, and so on

Use quotes to search for an exact phrase

"primary prevention of cancer"
(heart or cardiac or cardio*) AND arrest -"American Heart Association"