journal
MENU ▼
Read by QxMD icon Read
search

Transplant International: Official Journal of the European Society for Organ Transplantation

journal
https://www.readbyqxmd.com/read/29150966/current-policy-for-allocation-of-donor-livers-in-the-netherlands-advantages-primary-sclerosing-cholangitis-patients-on-the-liver-transplantation-waiting-list-a-retrospective-study
#1
Jorn C Goet, Bettina E Hansen, Madelon Tieleman, Bart van Hoek, Aad P van den Berg, Wojciech G Polak, Jeroen Dubbeld, Robert J Porte, Cynthia Konijn, Robert A de Man, Herold J Metselaar, Annemarie C de Vries
Studies from the United States and Nordic countries indicate primary sclerosing cholangitis (PSC) patients have low mortality on the liver transplantation (LTx) waiting list. However, this may vary among geographical areas. Therefore, we compared waiting list mortality and post-transplant survival between Laboratory Model for End Stage Liver Disease (LM) and MELD Exception (ME) prioritized PSC and non-PSC candidates in a nationwide study in the Netherlands. A retrospective analysis of patients waitlisted from 2006 to 2013 was conducted...
November 18, 2017: Transplant International: Official Journal of the European Society for Organ Transplantation
https://www.readbyqxmd.com/read/29150964/de-novo-donor-specific-hla-antibodies-after-combined-intestinal-and-vascularised-composite-allotransplantation
#2
Annemarie Weissenbacher, Georgios Vrakas, Mian Chen, Srikanth Reddy, Philip Allan, Henk Giele, Martin Cnm Barnardo, Anil Vaidya, Peter J Friend, Susan V Fuggle
Combining vascularised composite allotransplantation (VCA) with intestinal transplantation to achieve primary abdominal closure has become a feasible procedure. Besides facilitating closure, the abdominal wall can be used to monitor intestinal rejection. As the inclusion of a VCA raises the possibility of an enhanced alloimmune response, we investigated the incidence and clinical effect of de novo donor specific HLA antibodies (dnDSA) in a cohort of patients receiving an intestinal transplant with or without a VCA...
November 18, 2017: Transplant International: Official Journal of the European Society for Organ Transplantation
https://www.readbyqxmd.com/read/29130558/right-lobe-donor-hepatectomy-is-it-safe
#3
Sanjay Goja, Sanjay Kumar Yadav, Sanjiv Saigal, Arvinder Singh Soin
INTRODUCTION: Donor safety is utmost important in Living donor liver transplantation (LDLT). Small for size syndrome in some recipients with left lobe donors led to the evolution of right lobe LDLT. AIM: To analyse the safety of large series of right lobe (RL) donor hepatectomies and compare outcomes with left lobe (LL) and left lateral segment (LLS) donations. MATERIAL AND METHODS: A consecutive cohort of 726 donors from January 2011 to January 2014 were studied; RL (n=641, 88...
November 12, 2017: Transplant International: Official Journal of the European Society for Organ Transplantation
https://www.readbyqxmd.com/read/29130541/depression-social-support-and-clinical-outcomes-following-lung-transplantation
#4
Patrick J Smith, Laurie D Snyder, Scott M Palmer, Benson M Hoffman, Gregory L Stonerock, Krista K Ingle, Caroline K Saulino, James A Blumenthal
BACKGROUND: Depressive symptoms are common among lung transplant candidates and have been associated with poorer clinical outcomes in some studies. Previous studies have been plagued by methodologic problems, including small sample sizes, few clinical events, and uncontrolled confounders, particularly perioperative complications. In addition, few studies have examined social support as a potential protective factor. We therefore examined the association between pre-transplant depressive symptoms, social support, and mortality in a large sample of lung transplant recipients...
November 12, 2017: Transplant International: Official Journal of the European Society for Organ Transplantation
https://www.readbyqxmd.com/read/29130538/-what-if-this-is-my-chance-to-save-my-life-a-semi-structured-interview-study-on-the-motives-and-experiences-of-esrd-patients-who-engaged-in-public-solicitation-of-a-living-kidney-donor
#5
Mathilde C Pronk, Dorthe Slaats, Willij C Zuidema, Medard T Hilhorst, Frank J M F Dor, Michiel Betjes, Willem Weimar, Jacqueline van de Wetering, Emma K Massey
The increase of patients using public solicitation (PS) to find a living kidney donor has generated a debate about the ethical complexities of PS. To investigate why patients engaged in PS and what they experienced during PS we conducted semi-structured interviews with 20 Dutch end-stage renal disease patients who had publicly solicited a living donor. Transcipts were thematically analyzed. We identified ten themes on patients' considerations preceding PS: cautiousness in discussing living donation within social network; reluctance to accept a kidney from loved ones; rejection/withdrawal of related donor candidates; moral objections to black market organs/paid donation; the ease of social media; encouraged by others; ends justyfying the means; despair and urge to take action; public disclosure of vulnerability; fear of being (perceived to be) selfish...
November 12, 2017: Transplant International: Official Journal of the European Society for Organ Transplantation
https://www.readbyqxmd.com/read/29130535/between-center-disparities-in-access-to-heart-transplantation-in-france-contribution-of-candidate-and-center-factors
#6
Christelle Cantrelle, Richard Dorent, Emilie Savoye, Philippe Tuppin, Guillaume Lebreton, Camille Legeai, Olivier Bastien
Transplantation represents the last option for patients with advanced heart failure. We assessed between-center disparities in access to heart transplantation in France one year after registration and evaluated the contribution of factors to these disparities. Adults (n=2,347) registered on the French national waiting list between January 1, 2010 and December 31, 2014 in the 23 transplant centers were included. Associations between candidate and transplant center characteristics and access to transplantation were assessed by proportional hazards frailty models...
November 12, 2017: Transplant International: Official Journal of the European Society for Organ Transplantation
https://www.readbyqxmd.com/read/29130583/endoscopic-retrograde-cholangio-pancreatography-in-the-management-of-biliary-complications-after-paediatric-liver-transplantation
#7
Sivaramakrishnan Venkatesh Karthik, Seng-Hock Quak, Marion M Aw
BACKGROUND: The published paediatric experience with Endoscopic retrograde cholangio-pancreatography (ERCP) in the diagnosis and management of biliary complications following liver transplantation (LT) is limited. AIMS: We describe our experience with ERCP in the management of children following LT who presented with biliary complications, over a 20 year period (1995-2014). METHODS: The retrospectively reviewed data is summarized descriptively...
November 11, 2017: Transplant International: Official Journal of the European Society for Organ Transplantation
https://www.readbyqxmd.com/read/29108097/routine-haemostasis-testing-before-transplanted-kidney-biopsy-a-cohort-study
#8
Gerhardus J A J M Kuiper, Maarten H L Christiaans, Monique H J M Mullens, Hugo Ten Cate, Karly Hamulýak, Yvonne M C Henskens
BACKGROUND: Kidney biopsy can result in bleeding complications. Pre-biopsy testing using bleeding time (BT) is controversial. New whole blood haemostasis tests, like platelet function analyser 100 (PFA-100) and multiple electrode aggregometer (MEA) might perform better. We postulated that PFA-100 would be suitable to replace BT pre-biopsy. METHODS: In 154 patients, transplanted kidney biopsies were performed after measurement of bleeding time, PFA-100, MEA, and mean platelet volume (MPV)...
November 6, 2017: Transplant International: Official Journal of the European Society for Organ Transplantation
https://www.readbyqxmd.com/read/29090502/endoscopic-treatment-of-anastomotic-biliary-stricture-after-adult-deceased-donor-liver-transplantation-with-multiple-plastic-stents-versus-self-expandable-metal-stents-a-systematic-review-and-meta-analysis
#9
REVIEW
Filippo Landi, Nicola de'Angelis, Ailton Sepulveda, Aleix Martínez-Pérez, Iradj Sobhani, Alexis Laurent, Olivier Soubrane
BACKGROUND: Anastomotic biliary strictures (ABSs) occur in up to 15% of patients after liver transplantation (LT). The aim of this study was to compare the efficacy and safety of self-expandable metal stents (SEMS) versus multiple plastic stents (MPS). METHODS: Databases were searched through April 2017. The outcome measures were technical success, stricture resolution, recurrence and complications. We synthesized the findings descriptively and performed a meta-analysis...
November 1, 2017: Transplant International: Official Journal of the European Society for Organ Transplantation
https://www.readbyqxmd.com/read/29082567/graft-intolerance-syndrome-requiring-graft-nephrectomy-after-late-kidney-graft-failure-can-it-be-predicted
#10
Kim L W Bunthof, Carmen M Verhoeks, Jan A J G van den Brand, Luuk B Hilbrands
BACKGROUND: Graft nephrectomy is recommended in case of early graft failure. When the graft fails more than 3-6 months after transplantation it is current practice to follow a wait-and-see policy. A common indication for graft removal is the graft intolerance syndrome. We aimed to create a risk prediction model for the occurrence of graft intolerance resulting in graft nephrectomy. METHODS: We collected data of kidney transplantations performed in our centre between 1980 and 2010 that failed at least 6 months after transplantation...
October 30, 2017: Transplant International: Official Journal of the European Society for Organ Transplantation
https://www.readbyqxmd.com/read/29057524/organ-transplantation-from-increased-infectious-risk-donors-the-experience-of-the-nord-italia-transplant-program-a-retrospective-study
#11
Paolo Antonio Grossi, Daniela Dalla Gasperina, Domenico Lombardi, Andrea Ricci, Giuseppe Piccolo, Alessandro Nanni Costa
The purpose of this study was to assess the safety and the clinical outcome associated with organ transplantation from increased infectious risk donors (IRD). We retrospectively identified all adult deceased IRD referred to the Nord Italia Transplant program coordinating center from November 2006 to November 2011. All potential donors were screened for social risk factors that may increase the risk of donor-derived infection with human immunodeficiency (HIV), hepatitis B virus (HBV), or hepatitis C virus (HCV)...
October 23, 2017: Transplant International: Official Journal of the European Society for Organ Transplantation
https://www.readbyqxmd.com/read/29057508/impact-of-antiviral-prophylaxis-in-adults-ebv-seronegative-kidney-recipients-on-early-and-late-ptld-onset-a-retrospective-cohort-study
#12
Simon Ville, Berthe-Marie Imbert-Marcille, Marianne Coste-Burel, Claire Garandeau, Aurélie Meurette, Diego Cantarovitch, Magali Giral, Maryvonne Hourmant, Gilles Blancho, Jacques Dantal
Post-transplantation lympho-proliferative disorder (PTLD) pathogenesis is related to EBV infection. Mismatch with the donor (EBV D+/R-) is the main risk factor for both early PTLD (< 1 year post transplantation) and late (> 1 year). In these at-risk patients, the role of antiviral prophylaxis for preventing PTLD remains controversial. We analysed the impact of antiviral drugs given to prevent CMV disease in a mono-centric retrospective cohort of 73 adult kidney or kidney-pancreas EBV seronegative recipients, transplanted between 01/01/2000 and 01/01/2016...
October 23, 2017: Transplant International: Official Journal of the European Society for Organ Transplantation
https://www.readbyqxmd.com/read/29030886/genetics-of-acute-rejection-after-kidney-transplantation
#13
REVIEW
Casey R Dorr, William S Oetting, Pamala A Jacobson, Ajay K Israni
Treatment of acute rejection (AR) following kidney transplantation has improved in recent years, but there are still limitations to successful outcomes. This review article covers literature in regard to recipient and donor genetics of AR kidney and secondarily of liver allografts. Many candidate gene and some genome-wide association studies (GWASs) have been conducted for AR in kidney transplantation. Genetic associations with AR in kidney and liver are mostly weak, and in most cases, the associations have not been reproducible...
October 14, 2017: Transplant International: Official Journal of the European Society for Organ Transplantation
https://www.readbyqxmd.com/read/29024071/an-unjustified-benefit-immortal-time-bias-in-the-analysis-of-time-dependent-events
#14
REVIEW
Andreas Gleiss, Rainer Oberbauer, Georg Heinze
Immortal time bias is a problem arising from methodologically wrong analyses of time-dependent events in survival analyses. We illustrate the problem by analysis of a kidney transplantation study. Following patients from transplantation to death, groups defined by the occurrence or nonoccurrence of graft failure during follow-up seemingly had equal overall mortality. Such naive analysis assumes that patients were assigned to the two groups at time of transplantation, which actually are a consequence of occurrence of a time-dependent event later during follow-up...
October 11, 2017: Transplant International: Official Journal of the European Society for Organ Transplantation
https://www.readbyqxmd.com/read/29024051/lifetime-end-stage-kidney-disease-risk-estimation-in-living-kidney-donor-candidates-remains-a-challenge
#15
LETTER
Darren Lee, John B Whitlam, Natasha Cook, Momena Manzoor, Geoff Harley, Suet-Wan Choy, Lawrence P McMahon, Matthew A Roberts
No abstract text is available yet for this article.
October 11, 2017: Transplant International: Official Journal of the European Society for Organ Transplantation
https://www.readbyqxmd.com/read/29024009/is-kidney-transplantation-safe-after-careful-selection-of-the-recipients-with-a-history-of-psychotic-disorder
#16
Miklos Z Molnar
The prevalence of both bipolar disorder and schizophrenia is around 1-4% in the general population and represents a relative contraindication for kidney transplantation. There are several reasons for this, including concerns in relation to relapse of psychiatric illness, medication and other post-transplant treatment non-adherence, inadequate social support, emotional and cognitive capability, and potential drug interactions between psychotropic and immunosuppressant medications. Only a small proportion of recipients with psychotic disorder has eventually been transplanted...
October 11, 2017: Transplant International: Official Journal of the European Society for Organ Transplantation
https://www.readbyqxmd.com/read/28987015/center-practice-drives-variation-in-choice-of-u-s-kidney-transplant-induction-therapy-a-retrospective-analysis-of-contemporary-practice
#17
V R Dharnidharka, A S Naik, D A Axelrod, M A Schnitzler, Z Zhang, S Bae, D L Segev, D C Brennan, T Alhamad, R Ouseph, N N Lam, M Nazzal, H Randall, B L Kasiske, M McAdams-Demarco, K L Lentine
To assess factors that influence the choice of induction regimen in contemporary kidney transplantation, we examined center-identified, national transplant registry data for 166,776 US recipients (2005-2014). Bi-level hierarchical models were constructed, wherein use of each regimen was compared pairwise with use of interleukin-2 receptor blocking antibodies (IL2rAb). Overall, 81.8% of patients received induction, including thymoglobulin (TMG, 46.0%), IL2rAb (21.9%), alemtuzumab (ALEM, 12.5%), and other agents (1...
October 7, 2017: Transplant International: Official Journal of the European Society for Organ Transplantation
https://www.readbyqxmd.com/read/28945291/safety-of-renal-transplantation-in-patients-with-bipolar-or-psychotic-disorders-a-retrospective-study
#18
Tomek Kofman, Franck Pourcine, Florence Canoui-Poitrine, Nassim Kamar, Paolo Malvezzi, Hélène François, Emmanuelle Boutin, Vincent Audard, Philippe Lang, Frank Martinez, Christophe Legendre, Marie Matignon, Philippe Grimbert
Solid organ transplantation societies recommend a relative contraindication of transplantation for people with bipolar or psychotic disorders. Very few data are available on the outcome of kidney transplantation and the increased risk of kidney disease in those patients. We conducted a retrospective multicenter cohort study (1979-2014) including kidney allograft recipients with either bipolar (BD) or psychotic disorders prior to transplant. Objectives were kidney allograft and patient outcomes compared to a matched control group without psychiatric disorders and the evolution of psychiatric disorder at 60 months after transplantation...
September 25, 2017: Transplant International: Official Journal of the European Society for Organ Transplantation
https://www.readbyqxmd.com/read/28940695/herpes-zoster-in-kidney-transplant-recipients-protective-effect-of-anti-cytomegalovirus-prophylaxis-and-natural-killer-cell-count-a-single-center-cohort-study
#19
Mario Fernández-Ruiz, Julia Origüen, David Lora, Francisco López-Medrano, Esther González, Natalia Polanco, Rafael San Juan, Tamara Ruiz-Merlo, Patricia Parra, Amado Andrés, José María Aguado
Despite its impact on quality of life and potential for complications, specific risk and protective factors for herpes zoster (HZ) after kidney transplantation (KT) remain to be clarified. We included 444 patients undergoing KT between November 2008 and March 2013. Peripheral blood lymphocyte subpopulations were measured at baseline and months 1 and 6. The risk factors for early (first post-transplant year) and late HZ (years 1-5) were separately assessed. We observed 35 episodes of post-transplant HZ after a median follow-up of 48...
September 22, 2017: Transplant International: Official Journal of the European Society for Organ Transplantation
https://www.readbyqxmd.com/read/28940684/the-cold-hard-facts-seasonal-variation-in-outcomes-after-kidney-transplantation
#20
Wai H Lim, Germaine Wong
Seasonal variation in the incidence and cardiovascular disease complications in the general population has been well documented (1) . According to analysis of data from the United States Renal Data System (USRDS) of all prevalent end-stage kidney disease (ESKD) patients between 2000 and 2013, the transition to ESKD (i.e. initiation of renal replacement therapy) and the incidence of all-cause and cause-specific mortality in patients with ESKD were highest during winter months (particularly January) compared to summer months, suggesting the possibility of season-specific precipitants during winter months contributing to adverse outcomes in both the general population and in patients with ESKD (2) ...
September 22, 2017: Transplant International: Official Journal of the European Society for Organ Transplantation
journal
journal
20283
1
2
Fetch more papers »
Fetching more papers... Fetching...
Read by QxMD. Sign in or create an account to discover new knowledge that matter to you.
Remove bar
Read by QxMD icon Read
×

Search Tips

Use Boolean operators: AND/OR

diabetic AND foot
diabetes OR diabetic

Exclude a word using the 'minus' sign

Virchow -triad

Use Parentheses

water AND (cup OR glass)

Add an asterisk (*) at end of a word to include word stems

Neuro* will search for Neurology, Neuroscientist, Neurological, and so on

Use quotes to search for an exact phrase

"primary prevention of cancer"
(heart or cardiac or cardio*) AND arrest -"American Heart Association"