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Transplantation Proceedings

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https://www.readbyqxmd.com/read/29678268/development-of-a-screening-tool-to-predict-chronic-kidney-disease-risk-in-post-nephrectomy-living-kidney-donors
#1
J S Park, H K Ahn, J Na, H H Lee, Y E Yoon, M G Yoon, W K Han
Few studies have examined the long-term risks of kidney removal to donors despite the increase of frequency in kidney transplantation. This is the 1st study to develop prediction models of chronic kidney disease (CKD) for the 1-year period after donor nephrectomy in living donors. A prospective cohort of patients who underwent donor nephrectomy from March 1, 2006, to December 31, 2016, at the Severance Hospital, Seoul, South Korea, was used. CKD was defined as a glomerular filtration rate (GFR) <60 mL/min/1...
April 17, 2018: Transplantation Proceedings
https://www.readbyqxmd.com/read/29678267/comparison-of-recipient-outcomes-after-kidney-transplantation-in-house-versus-imported-deceased-donors
#2
S Y Lim, J G Gwon, M G Kim, C W Jung
BACKGROUND: Increased cold ischemia time in cadaveric kidney transplants has been associated with a high rate of delayed graft function (DGF), and even with graft survival. Kidney transplantation using in-house donors reduces cold preservation time. The purpose of this study was to compare the clinical outcomes after transplantation in house and externally. METHODS: We retrospectively reviewed the medical records of donors and recipients of 135 deceased-donor kidney transplantations performed in our center from March 2009 to March 2016...
April 17, 2018: Transplantation Proceedings
https://www.readbyqxmd.com/read/29655492/isolated-acute-appendicitis-caused-by-aspergillus-in-a-patient-who-underwent-lung-transplantation-a-case-report
#3
H S Kim, H J Yeo, D H Shin, W H Cho, D Kim
Invasive aspergillosis is an important cause of morbidity and mortality in patients who have undergone lung transplantation. Aspergillus infections usually involve the respiratory tract, with vascular invasion and subsequent dissemination. However, acute appendicitis associated with localized aspergillosis is rare, especially among patients who have undergone prophylaxis with voriconazole. We present a case of primary Aspergillus appendicitis diagnosed by histologic examination in a patient who underwent lung transplantation...
April 11, 2018: Transplantation Proceedings
https://www.readbyqxmd.com/read/29631750/steroid-withdrawal-using-everolimus-in-abo-incompatible-kidney-transplant-recipients-with-post-transplant-diabetes-mellitus
#4
K Nanmoku, T Shinzato, T Kubo, T Shimizu, T Kimura, T Yagisawa
BACKGROUND: The effectiveness of everolimus (EVR) for ABO-incompatible (ABOi) kidney transplantation is unknown. We evaluated outcomes of conversion from steroid to EVR in ABOi kidney transplant recipients. METHODS: We performed a retrospective observational cohort study of 33 de novo consecutive adult ABOi living donor kidney transplant recipients. Desensitization was performed using 0 to 4 sessions of plasmapheresis and 1 to 2 doses of 100 mg rituximab according to the anti-A/B antibody titer...
April 6, 2018: Transplantation Proceedings
https://www.readbyqxmd.com/read/29588066/life-threatening-everolimus-associated-pneumonitis-a-case-report-and-a-review-of-the-literature
#5
F Almeida, S Amorim, A Sarmento, L Santos
INTRODUCTION: Noninfective pneumonitis is a class-related effect within mammalian target of rapamycin (mTOR) inhibitors, including everolimus, and can occasionally be severe. CASE REPORT: A 62-year-old man, medicated with everolimus due to a heart transplantation 17 years previously and with chronic kidney disease, was admitted to the intensive care unit (ICU) with acute respiratory failure, cardiovascular shock, and impaired renal function requiring dialysis. Computed tomography (CT) scan revealed right upper lobe consolidation...
March 24, 2018: Transplantation Proceedings
https://www.readbyqxmd.com/read/29588065/atypical-presentation-of-escherichia-coli-monomicrobial-necrotizing-fasciitis-in-a-renal-transplant-patient-a-case-report
#6
S Afghani, V Ngo, T Khan, V Lewis
Skin and soft tissue infections (SSTIs) are one of most frequent infectious causes for referral to the emergency department and one of the most frequent infectious causes of hospital admissions. Escherichia coli, the most commonly occurring gram-negative pathogen involved in these infections, contributes to about 7% of all SSTIs cases where gram-positive organisms reign dominant. Patients are more susceptible to these gram-negative SSTIs if they are neutropenic, have hematologic malignancies, have undergone solid organ or hematopoietic transplantation, or have cirrhotic liver disease...
March 24, 2018: Transplantation Proceedings
https://www.readbyqxmd.com/read/29571743/acute-inflammatory-syndrome-paradoxically-induced-by-de-novo-purine-inhibitors-synthesis-before-renal-transplantation-a-case-report-and-review-of-the-literature
#7
Y Maruyama, T Sadahira, Y Mitsui, K Wada, R Tanimoto, S Nishimura, Y Kobayashi, T Watanabe, Y Nasu, M Araki
BACKGROUND: Mycophenolate mofetil (MMF) and mizoribine (MZR) are increasingly used as immunosuppressive agents for organ transplantation and chronic inflammation. We report a patient with rheumatoid arthritis who had an acute inflammatory syndrome triggered by preoperative immunosuppression therapy with both MMF and MZR. CASE REPORT: A 41-year-old woman with IgA nephropathy was referred to our department for living donor renal transplantation. She had rheumatoid arthritis that was adequately treated with prednisolone 5 mg once a day and salazosulfapyridine 2000 mg once a day...
March 21, 2018: Transplantation Proceedings
https://www.readbyqxmd.com/read/29571742/family-interview-to-enable-donation-of-organs-for-transplantation-evidence-based-practice
#8
E L de Moraes, M J Dos Santos, L B de Barros E Silva, L A S de Lima Pilan, E A A de Lima, A C de Santana, M S Martins
BACKGROUND: In this study we propose a theoretical and practical basis for the best practices for interviewing relatives of brain-dead eligible organ donors. METHODS: This investigation was a reflective study of the methodologic factors of the family interview that affect their decision regarding the donation of a deceased patient's organs for transplantation. The articles that formed the empirical basis of the trial were obtained from PubMed, which is a free-access tool of the MEDLINE database of the United States National Library of Medicine...
March 21, 2018: Transplantation Proceedings
https://www.readbyqxmd.com/read/29555247/post-keratoplasty-endophthalmitis-by-multidrug-resistant-pseudomonas-aeruginosa-with-positive-culture-of-the-contralateral-donor-cornea-a-case-report
#9
J C Serna-Ojeda, L Pedro-Aguilar, C Rodriguez-Quintanilla, H Mejía-López, D G Ponce-Angulo, A Navas, V M Bautista-de Lucio, E O Graue-Hernandez
PURPOSE: The aim of this paper is to present the case report of a patient developing endophthalmitis after penetrating keratoplasty caused by a multidrug-resistant Pseudomonas aeruginosa, detected only in the contralateral donor tissue. CASE REPORT: A 77-year-old man underwent an uneventful penetrating keratoplasty with a preoperative culture-negative donor cornea; however, the fellow cornea grew multidrug-resistant Pseudomonas aeruginosa. The patient developed and was treated for endophthalmitis after penetrating keratoplasty, and aqueous and vitreous taps grew P...
March 16, 2018: Transplantation Proceedings
https://www.readbyqxmd.com/read/29555246/functional-outcomes-18-months-after-total-and-midarm-transplantation-a-case-report
#10
M Iglesias, M Ramírez-Berumen, P Butrón, J Alberú-Gómez, F Salazar-Hernández, J Macias-Gallardo, R P Leal-Villalpando, J Zamudio-Bautista, V Acosta, L Jauregui, A Hernández-Campos, V Espinosa-Cruz, J Vázquez-Lamadrid, J González-Sánchez, J Cuellar-Rodriguez, J G Sierra-Madero, R Gaytan-Cervantes, S Contreras-Barbosa, A Navarro-Lara, J Guzman-Gonzalez, J Domínguez-Cherit, M Vilatoba, S Toussaint-Caire, F Vega-Boada, F J Gómez-Pérez, M Mayorquin-Ruiz
BACKGROUND: The function reported after arm transplantation is deemed beneficial relative to the marked disability that upper arm amputation causes. OBJECTIVE: We report a 51-year-old man with a Disabilities of the Arm, Shoulder and Hand (DASH) score of 75.83 who underwent bilateral arm transplantation in October 2015. PROCEDURE: The right arm was transplanted at the glenohumeral joint level, including transplantation of the humeral head, joint capsule, and rotator cuff ligaments and tendons...
March 16, 2018: Transplantation Proceedings
https://www.readbyqxmd.com/read/29555245/case-report-spontaneous-hemorrhage-of-a-rare-renal-tumor-in-the-native-kidney-of-a-renal-transplant-recipient
#11
A L Tan, M Lawson, J Preston, S Wood, A Griffin, H Rhee
Renal cancers are some of the most common solid organ malignancies found during follow-up of patients who have undergone renal transplantation (RT). In this case report, we describe a life-threatening spontaneous hemorrhage of a rare subtype of renal cell carcinoma in the native kidney of a 27-year-old man, 4 years after RT. After fluid resuscitation and stabilization, the patient underwent emergent open radical nephrectomy with the final histopathology reporting T1bN0Mx mucinous tubular and spindle cell (MTSC) carcinoma...
March 16, 2018: Transplantation Proceedings
https://www.readbyqxmd.com/read/29458999/case-report-first-reported-combined-heart-liver-transplant-in-a-patient-with-a-congenital-solitary-kidney
#12
R M Hanna, M Kamgar, H Hasnain, R Khorsan, A Nsair, F Kaldas, A Baas, S Bunnapradist, J M Wilson
We report a case of successful combined heart liver transplant in a patient with a congenital solitary kidney. The patient had normal renal function before combined heart-liver transplantation and developed acute kidney injury requiring slow continuous dialysis and subsequent intermittent dialysis for almost 8 weeks post transplantation. Her renal function recovered and she remains off dialysis now 7 months post transplantation. She only currently has mild chronic renal insufficiency. We believe this is the first reported case of successful heart liver transplant in a patient with a congenital solitary kidney...
February 16, 2018: Transplantation Proceedings
https://www.readbyqxmd.com/read/29661469/successful-7-year-eculizumab-treatment-of-plasmapheresis-resistant-recurrent-atypical-hemolytic-uremic-syndrome-due-to-complement-factor-h-hybrid-gene-a-case-report
#13
K Vondrák, T Seeman
Atypical hemolytic-uremic syndrome (aHUS) is an extremely rare disease, and up to 70% of the patients have a genetic mutation in the encoding components of complement activation or anti-complement factor H autoantibodies. The risk of recurrence after kidney transplantation is 10% to 80%. Eculizumab, a monoclonal antibody that binds complement protein C5, has shown to be highly effective in patients with aHUS; however, there are only few reports on the efficacy and safety of long-term eculizumab treatment in children with recurrent aHUS...
April 2018: Transplantation Proceedings
https://www.readbyqxmd.com/read/29661468/successful-treatment-of-cytogenetically-normal-acute-myeloid-leukemia-with-ten-eleven-translocation-2-isocitrate-dehydrogenase-2-and-additional-sex-comb-like-1-nucleophosmin-co-mutations-by-hla-haploidentical-stem-cell-transplantation-a-case-report-and-literature
#14
Y Liu, Y Cao, Y Lin, W-M Dong, R-R Lin, Q Gu, X-B Xie, W-Y Gu
The presence of recurrent gene mutations is increasingly important in acute myeloid leukemia (AML) and sheds new insights into the understanding of leukemogenesis, prognostic evaluation, and clinical therapeutic efficacy. Until now, ten-eleven translocation 2 (TET2) and isocitrate dehydrogenase 2 (IDH2) mutations were reported to be mutually exclusive in AML patients. Similarly, nucleophosmin (NPM1) and additional sex comb-like 1 (ASXL1) mutations were rarely coexisted in AML. A 47-year-old man diagnosed with high-risk AML presented simultaneous mutations of TET2-IDH2 and NPM1-ASXL1 revealed by next-generation sequencing...
April 2018: Transplantation Proceedings
https://www.readbyqxmd.com/read/29661467/paradoxical-reaction-of-tuberculosis-in-a-heart-transplant-recipient-during-antituberculosis-therapy-a-case-report
#15
A Wakamiya, O Seguchi, A Shionoiri, Y Kumai, K Kuroda, S Nakajima, M Yanase, S Matsuda, K Wada, Y Matsumoto, S Fukushima, T Fujita, J Kobayashi, N Fukushima
INTRODUCTION: Tuberculous paradoxical reactions (PRs) are excessive immune reactions occurring after antituberculosis (TB) treatment and are commonly observed in immunocompromised hosts such as patients infected with the human immunodeficiency virus. CASE REPORT: We recently encountered a 63-year-old male heart transplant recipient who developed tuberculous PR after treatment for miliary TB. The patient had been receiving immunosuppressive therapy with cyclosporine and mycophenolate mofetil for over 15 years...
April 2018: Transplantation Proceedings
https://www.readbyqxmd.com/read/29661466/endobronchial-topical-amphotericin-b-instillation-for-pulmonary-chromomycosis-after-lung-transplantation-a-case-report
#16
H Mitomo, A Sakurada, Y Matsuda, H Notsuda, T Watanabe, H Oishi, H Niikawa, S Maeda, M Noda, T Sado, T Amemiya, Y Yoshida, T Kikuchi, K Kamei, Y Okada
We report a very rare case of pulmonary chromomycosis caused by Scedosporium prolificans that developed after lung transplantation and was successfully treated with endobronchial topical amphotericin B instillation. The subject was a woman in her 50s with a history of bilateral lobar lung transplantation from living donors for idiopathic pulmonary hypertension. Eight years after the lung transplantation, chest radiography X-ray and computed tomography showed an abnormal shadow in the right lung. Bronchoscopic findings showed obstruction by a fungal component at the laterobasal bronchus B9...
April 2018: Transplantation Proceedings
https://www.readbyqxmd.com/read/29661465/allograft-portacaval-shunt-in-small-for-size-liver-in-deceased-donor-liver-transplant
#17
J H Nguyen, D M Harnois
Portal hyperperfusion is detrimental to small-for-size livers (SFSLs) in liver transplantation. Surgical techniques modulating portal inflow provide the most effective approach to protect the SFSL. In this report, we describe a technique creating an allograft portacaval shunt that effectively attenuates portal inflow without a requirement of extensive surgical dissection in the recipient during the transplantation.
April 2018: Transplantation Proceedings
https://www.readbyqxmd.com/read/29661464/cauliflower-like-neoplasm-of-duodenal-papilla-in-a-liver-transplant-recipient-what-should-we-think-and-do-a-case-report
#18
D-L Wan, M-X Li, L Bao, L-L Zhang, L Zhang, Q-Y Chen, S-Z Lin
BACKGROUND: With the continuous improvement of liver transplantation technology, the survival rate of liver transplantation has been improved, but recurrent or de novo malignancy remains one of the major factors affecting the long-term survival of liver transplant recipients. CASE REPORT: A 45-year-old Chinese man had a plastic biliary stent placed on account of biliary anastomotic stenosis after 3 years of piggyback liver transplantation. He came to our hospital because of recurrent fever and jaundice for 2 weeks, and his carcinoembryonic antigen-199 had increased...
April 2018: Transplantation Proceedings
https://www.readbyqxmd.com/read/29661463/case-report-of-multiple-bilobar-hepatic-arterio-portal-fistulas-post-liver-transplantation-managed-conservatively
#19
Y Puri, P Srinivasan, P Peddu, N Heaton
Multiple intrahepatic arterio-portal fistulas are rare. The majority are isolated and occur secondary to liver trauma including iatrogenic interventions such as liver biopsy. Post-liver transplantation 18 cases have been reported, all secondary to an interventional radiological procedure. We report multiple bi-lobar arterio-portal fistulas in a liver transplant recipient recognized 1 year after transplantation. The donor died due to intracerebral bleeding following blunt head and abdominal trauma. In the present case, the etiology is not very clear...
April 2018: Transplantation Proceedings
https://www.readbyqxmd.com/read/29661462/donor-derived-candida-dubliniensis-resulting-in-perigraft-abscesses-in-a-liver-transplant-recipient-proven-by-whole-genome-sequencing-a-case-report
#20
Y E Teh, M L T Ang, M V La, V Gunalan, C K Tan, A L Tan, R T P Lin, T T Tan, P R Jeyaraj, S Cumaraswamy, B H Tan
BACKGROUND: The transmission of fungi via transplant, although well-known, has not often been molecularly proven. We describe a case of donor-derived candidiasis verified by whole genome sequencing. CASE DESCRIPTION: The multiorgan donor was a 42-year-old woman with subdural hemorrhage. Procurement of the thoracic organs was performed followed by the abdominal organs. Tissue from the left bronchus grew Candida dubliniensis. The liver recipient was a 63-year-old woman with cryptogenic liver cirrhosis...
April 2018: Transplantation Proceedings
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