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Psychological Medicine

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https://www.readbyqxmd.com/read/28325167/virtual-reality-in-the-assessment-understanding-and-treatment-of-mental-health-disorders
#1
D Freeman, S Reeve, A Robinson, A Ehlers, D Clark, B Spanlang, M Slater
Mental health problems are inseparable from the environment. With virtual reality (VR), computer-generated interactive environments, individuals can repeatedly experience their problematic situations and be taught, via evidence-based psychological treatments, how to overcome difficulties. VR is moving out of specialist laboratories. Our central aim was to describe the potential of VR in mental health, including a consideration of the first 20 years of applications. A systematic review of empirical studies was conducted...
March 22, 2017: Psychological Medicine
https://www.readbyqxmd.com/read/28290271/diminished-modulation-of-preparatory-sensorimotor-mu-rhythm-predicts-attention-deficit-hyperactivity-disorder-severity
#2
N Ter Huurne, D Lozano-Soldevilla, M Onnink, C Kan, J Buitelaar, O Jensen
BACKGROUND: Attention-deficit/hyperactivity disorder (ADHD) is characterized by problems in regulating attention and in suppressing disruptive motor activity, i.e. hyperactivity and impulsivity. We recently found evidence that aberrant distribution of posterior α band oscillations (8-12 Hz) is associated with attentional problems in ADHD. The sensorimotor cortex also produces strong 8-12 Hz band oscillations, namely the μ rhythm, and is thought to have a similar inhibitory function...
March 14, 2017: Psychological Medicine
https://www.readbyqxmd.com/read/28290265/reduced-optimism-and-a-heightened-neural-response-to-everyday-worries-are-specific-to-generalized-anxiety-disorder-and-not-seen-in-social-anxiety
#3
K S Blair, M Otero, C Teng, M Geraci, M Ernst, R J R Blair, D S Pine, C Grillon
BACKGROUND: Generalized anxiety disorder (GAD) and social anxiety disorder (SAD) are co-morbid and associated with similar neural disruptions during emotion regulation. In contrast, the lack of optimism examined here may be specific to GAD and could prove an important biomarker for that disorder. METHOD: Unmedicated individuals with GAD (n = 18) and age-, intelligence quotient- and gender-matched SAD (n = 18) and healthy (n = 18) comparison individuals were scanned while contemplating likelihoods of high- and low-impact negative (e...
March 14, 2017: Psychological Medicine
https://www.readbyqxmd.com/read/28290262/stigma-related-barriers-and-facilitators-to-help-seeking-for-mental-health-issues-in-the-armed-forces-a-systematic-review-and-thematic-synthesis-of-qualitative-literature
#4
S J Coleman, S A M Stevelink, S L Hatch, J A Denny, N Greenberg
A recent quantitative review in the area of stigma and help seeking in the armed forces has questioned the association between these factors (Sharp et al. 2015). To date, the contribution of qualitative literature in this area has largely been ignored, despite the value this research brings to the understanding of complex social constructs such as stigma. The aim of the current systematic review of qualitative studies was to identify appropriate literature, assess the quality and synthesize findings across studies regarding evidence of stigma-related barriers and facilitators to help seeking for mental health issues within the armed forces...
March 14, 2017: Psychological Medicine
https://www.readbyqxmd.com/read/28287059/subjective-measures-of-health-and-all-cause-mortality-the-rotterdam-study
#5
A Sajjad, R L Freak-Poli, A Hofman, S J Roza, M A Ikram, H Tiemeier
BACKGROUND: Subjectively assessed health is related to mortality. Various subjective indicators of health have been studied, but it is unclear whether perceived physical functioning or mental health best accounts for the relation with mortality. METHOD: We studied the relation of subjective measures of health with all-cause mortality in 5538 participants of age 55 to 96 years at baseline from the Rotterdam Study. Various instruments of subjectively assessed health were used, that included basic activities of daily living (BADL), instrumental activities of daily living (IADL), quality of life (QoL), positive affect, somatic symptoms and negative affect...
March 13, 2017: Psychological Medicine
https://www.readbyqxmd.com/read/28274297/letter-to-the-editor-electrode-placement-in-electroconvulsive-therapy-bilateral-is-still-the-gold-standard-for-some-patients-a-reply
#6
E Kolshus, A Jelovac, D M McLoughlin
No abstract text is available yet for this article.
March 9, 2017: Psychological Medicine
https://www.readbyqxmd.com/read/28274287/letter-to-the-editor-electrode-placement-in-electroconvulsive-therapy-bilateral-is-still-the-gold-standard-for-some-patients
#7
C H Kellner, M Cicek, J L Ables
No abstract text is available yet for this article.
March 9, 2017: Psychological Medicine
https://www.readbyqxmd.com/read/28249639/baseline-demographics-clinical-features-and-predictors-of-conversion-among-200-individuals-in-a-longitudinal-prospective-psychosis-risk-cohort
#8
G Brucato, M D Masucci, L Y Arndt, S Ben-David, T Colibazzi, C M Corcoran, A H Crumbley, F M Crump, K E Gill, D Kimhy, A Lister, S A Schobel, L H Yang, J A Lieberman, R R Girgis
BACKGROUND: DSM-5 proposes an Attenuated Psychosis Syndrome (APS) for further investigation, based upon the Attenuated Positive Symptom Syndrome (APSS) in the Structured Interview for Psychosis-Risk Syndromes (SIPS). SIPS Unusual Thought Content, Disorganized Communication and Total Disorganization scores predicted progression to psychosis in a 2015 NAPLS-2 Consortium report. We sought to independently replicate this in a large single-site high-risk cohort, and identify baseline demographic and clinical predictors beyond current APS/APSS criteria...
March 2, 2017: Psychological Medicine
https://www.readbyqxmd.com/read/28241891/characterizing-cognitive-heterogeneity-on-the-schizophrenia-bipolar-disorder-spectrum
#9
T E Van Rheenen, K E Lewandowski, E J Tan, L H Ospina, D Ongur, E Neill, C Gurvich, C Pantelis, A K Malhotra, S L Rossell, K E Burdick
BACKGROUND: Current group-average analysis suggests quantitative but not qualitative cognitive differences between schizophrenia (SZ) and bipolar disorder (BD). There is increasing recognition that cognitive within-group heterogeneity exists in both disorders, but it remains unclear as to whether between-group comparisons of performance in cognitive subgroups emerging from within each of these nosological categories uphold group-average findings. We addressed this by identifying cognitive subgroups in large samples of SZ and BD patients independently, and comparing their cognitive profiles...
February 28, 2017: Psychological Medicine
https://www.readbyqxmd.com/read/28238294/within-subject-neural-reactivity-to-reward-and-threat-is-inverted-in-young-adolescents
#10
M E Thomason, H A Marusak
BACKGROUND: As children mature, they become increasingly independent and less reliant on caregiver support. Changes in brain systems are likely to stimulate and guide this process. One mechanistic hypothesis suggests that changes in neural systems that process reward and threat support the increase in exploratory behavior observed in the transition to adolescence. This study examines the basic tenets of this hypothesis by performing functional magnetic resonance imaging (fMRI) during well-established reward and threat processing tasks in 40 children and adolescents, aged 9-15 years...
February 27, 2017: Psychological Medicine
https://www.readbyqxmd.com/read/28228182/cost-effectiveness-of-computerized-cognitive-behavioural-therapy-for-the-treatment-of-depression-in-primary-care-findings-from-the-randomised-evaluation-of-the-effectiveness-and-acceptability-of-computerised-therapy-reeact-trial
#11
A Duarte, S Walker, E Littlewood, S Brabyn, C Hewitt, S Gilbody, S Palmer
BACKGROUND: Computerized cognitive-behavioural therapy (cCBT) forms a core component of stepped psychological care for depression. Existing evidence for cCBT has been informed by developer-led trials. This is the first study based on a large independent pragmatic trial to assess the cost-effectiveness of cCBT as an adjunct to usual general practitioner (GP) care compared with usual GP care alone and to establish the differential cost-effectiveness of a free-to-use cCBT programme (MoodGYM) in comparison with a commercial programme (Beating the Blues) in primary care...
February 23, 2017: Psychological Medicine
https://www.readbyqxmd.com/read/28222825/combined-universal-and-selective-prevention-for-adolescent-alcohol-use-a-cluster-randomized-controlled-trial
#12
M Teesson, N C Newton, T Slade, N Carragher, E L Barrett, K E Champion, E V Kelly, N K Nair, L A Stapinski, P J Conrod
BACKGROUND: No existing models of alcohol prevention concurrently adopt universal and selective approaches. This study aims to evaluate the first combined universal and selective approach to alcohol prevention. METHOD: A total of 26 Australian schools with 2190 students (mean age: 13.3 years) were randomized to receive: universal prevention (Climate Schools); selective prevention (Preventure); combined prevention (Climate Schools and Preventure; CAP); or health education as usual (control)...
February 22, 2017: Psychological Medicine
https://www.readbyqxmd.com/read/28222824/curiosity-killed-the-cat-no-evidence-of-an-association-between-cat-ownership-and-psychotic-symptoms-at-ages-13-and-18-years-in-a-uk-general-population-cohort
#13
F Solmi, J F Hayes, G Lewis, J B Kirkbride
BACKGROUND: Congenital or early life infection with Toxoplasma gondii has been implicated in schizophrenia aetiology. Childhood cat ownership has been hypothesized as an intermediary marker of T. gondii infection and, by proxy, as a risk factor for later psychosis. Evidence supporting this hypothesis is, however, limited. METHOD: We used birth cohort data from the Avon Longitudinal Study of Parents and Children (ALSPAC) to investigate whether cat ownership in pregnancy and childhood (ages 4 and 10 years) was associated with psychotic experiences (PEs) in early (age 13, N = 6705) and late (age 18, N = 4676) adolescence, rated from semi-structured interviews...
February 22, 2017: Psychological Medicine
https://www.readbyqxmd.com/read/28222820/the-cross-national-epidemiology-of-specific-phobia-in-the-world-mental-health-surveys
#14
K J Wardenaar, C C W Lim, A O Al-Hamzawi, J Alonso, L H Andrade, C Benjet, B Bunting, G de Girolamo, K Demyttenaere, S E Florescu, O Gureje, T Hisateru, C Hu, Y Huang, E Karam, A Kiejna, J P Lepine, F Navarro-Mateu, M Oakley Browne, M Piazza, J Posada-Villa, M L Ten Have, Y Torres, M Xavier, Z Zarkov, R C Kessler, K M Scott, P de Jonge
BACKGROUND: Although specific phobia is highly prevalent, associated with impairment, and an important risk factor for the development of other mental disorders, cross-national epidemiological data are scarce, especially from low- and middle-income countries. This paper presents epidemiological data from 22 low-, lower-middle-, upper-middle- and high-income countries. METHOD: Data came from 25 representative population-based surveys conducted in 22 countries (2001-2011) as part of the World Health Organization World Mental Health Surveys initiative (n = 124 902)...
February 22, 2017: Psychological Medicine
https://www.readbyqxmd.com/read/28202098/gene-environment-interplay-in-depressive-symptoms-moderation-by-age-sex-and-physical-illness
#15
A J Petkus, C R Beam, W Johnson, J Kaprio, T Korhonen, M McGue, J M Neiderhiser, N L Pedersen, C A Reynolds, M Gatz
BACKGROUND: Numerous factors influence late-life depressive symptoms in adults, many not thoroughly characterized. We addressed whether genetic and environmental influences on depressive symptoms differed by age, sex, and physical illness. METHOD: The analysis sample included 24 436 twins aged 40-90 years drawn from the Interplay of Genes and Environment across Multiple Studies (IGEMS) Consortium. Biometric analyses tested age, sex, and physical illness moderation of genetic and environmental variance in depressive symptoms...
February 16, 2017: Psychological Medicine
https://www.readbyqxmd.com/read/28202095/the-effects-of-vitamin-and-mineral-supplementation-on-symptoms-of-schizophrenia-a-systematic-review-and-meta-analysis
#16
J Firth, B Stubbs, J Sarris, S Rosenbaum, S Teasdale, M Berk, A R Yung
BACKGROUND: When used as an adjunctive with antipsychotics, certain vitamins and minerals may be effective for improving symptomatic outcomes of schizophrenia, by restoring nutritional deficits, reducing oxidative stress, or modulating neurological pathways. METHOD: We conducted a systematic review of all randomized controlled trials (RCTs) reporting effects of vitamin and/or mineral supplements on psychiatric symptoms in people with schizophrenia. Random-effects meta-analyses were used to calculate the standardized mean difference between nutrient and placebo treatments...
February 16, 2017: Psychological Medicine
https://www.readbyqxmd.com/read/28196554/impact-of-childhood-and-adulthood-psychological-health-on-labour-force-participation-and-exit-in-later-life
#17
C Clark, M Smuk, D Lain, S A Stansfeld, E Carr, J Head, S Vickerstaff
BACKGROUND: Adulthood psychological health predicts labour force activity but few studies have examined childhood psychological health. We hypothesized that childhood psychological ill-health would be associated with labour force exit at 55 years. METHOD: Data were from the 55-year follow-up of the National Child Development Study (n = 9137). Labour force participation and exit (unemployment, retirement, permanent sickness, homemaking/other) were self-reported at 55 years...
February 15, 2017: Psychological Medicine
https://www.readbyqxmd.com/read/28196550/genetic-and-environmental-influences-on-last-year-major-depression-in-adulthood-a-highly-heritable-stable-liability-but-strong-environmental-effects-on-1-year-prevalence
#18
K S Kendler, C O Gardner
BACKGROUND: This study seeks to clarify the contribution of temporally stable and occasion-specific genetic and environmental influences on risk for major depression (MD). METHOD: Our sample was 2153 members of female-female twin pairs from the Virginia Twin Registry. We examined four personal interview waves conducted over an 8-year period with MD in the last year defined by DSM-IV criteria. We fitted a structural equation model to the data using classic Mx. The model included genetic and environmental risk factors for a latent, stable vulnerability to MD and for episodes in each of the four waves...
February 15, 2017: Psychological Medicine
https://www.readbyqxmd.com/read/28196549/mental-health-related-stigma-and-pathways-to-care-for-people-at-risk-of-psychotic-disorders-or-experiencing-first-episode-psychosis-a-systematic-review
#19
P C Gronholm, G Thornicroft, K R Laurens, S Evans-Lacko
BACKGROUND: Stigma associated with mental illness can delay or prevent help-seeking and service contact. Stigma-related influences on pathways to care in the early stages of psychotic disorders have not been systematically examined. METHOD: This review systematically assessed findings from qualitative, quantitative and mixed-methods research studies on the relationship between stigma and pathways to care (i.e. processes associated with help-seeking and health service contact) among people experiencing first-episode psychosis or at clinically defined increased risk of developing psychotic disorder...
February 15, 2017: Psychological Medicine
https://www.readbyqxmd.com/read/28193313/community-based-screening-intervention-for-depression-affects-suicide-rates-among-middle-aged-japanese-adults
#20
H Oyama, T Sakashita
BACKGROUND: It has been suggested that screening interventions may be effective for suicide prevention. Few studies, however, have reported their effects on outcome measures, including death by suicide among middle-aged adults. METHOD: We used a quasi-experimental parallel cluster design with matched community-based intervention and control municipalities (total eligible population: 90 000) in Japan. At-risk residents within the intervention area were invited for universal depression screening and subsequent care/support...
February 14, 2017: Psychological Medicine
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