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BJOG: An International Journal of Obstetrics and Gynaecology

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https://www.readbyqxmd.com/read/30009579/reproductive-medicine-still-more-art-than-science
#1
J Wilkinson, S Bhattacharya, J M N Duffy, M S Kamath, J Marjoribanks, S Repping, A Vail, M van Wely, C M Farquhar
The history of obstetrics and gynaecology is not a tale of evidence-based practice. Tradition, expert opinion, and the lure of new technology have frequently superseded evidence as the primary driver for clinical decision making. The proof can be found in a litany of dubious interventions which have gained widespread popularity despite an absence of high quality data attesting to their effectiveness and, in some cases, ample credible evidence demonstrating harm. As a specialty, we have relied on investigations including X-ray pelvimetry and antenatal stress tests, subjected innumerable women to stilboestrol and thalidomide, and have performed routine episiotomy in all primigravid women 1,...
July 16, 2018: BJOG: An International Journal of Obstetrics and Gynaecology
https://www.readbyqxmd.com/read/30009547/-nausicaa-compression-suture-a-simple-and-effective-alternative-to-hysterectomy-in-placenta-accreta-spectrum-and-other-causes-of-severe-postpartum-haemorrhage
#2
Jin-Chung Shih, Kao-Lang Liu, Jessica Kang, Jehn-Hsiahn Yang, Ming-Wei Lin, Ching-Uen Yu
Postpartum haemorrhage (PPH), especially resulted from placenta accreta spectrum (PAS), has become a worldwide concern in maternity care. We described a novel method of uterine compression sutures ("Nausicaa" technique) as an alternative to hysterectomy for patients suffered from major PPH. We applied this technique in 68 patients with major PPH (including 43 patients of PAS, 20 patients of placenta previa totalis, and five patients with uterine atony) during caesarean section; and none of these patients required for further hysterectomy...
July 16, 2018: BJOG: An International Journal of Obstetrics and Gynaecology
https://www.readbyqxmd.com/read/30009461/do-we-need-a-core-outcome-set-for-childbirth-perineal-trauma-research-a-systematic-review-of-outcome-reporting-in-randomised-trials-evaluating-the-management-of-childbirth-trauma
#3
Vasilios Pergialiotis, Constantin Durnea, Abdullatif Elfituri, James M N Duffy, Stergios K Doumouchtsis
BACKGROUND: Selecting appropriate outcomes to reflect both beneficial and harmful effects is a critical step in designing childbirth trauma trials. OBJECTIVE: To evaluate the outcomes and outcomes measures reported in randomised controlled trials evaluating interventions for childbirth trauma. SEARCH STRATEGY: Randomised trials were identified by searching bibliographical databases including Cochrane Central Register of Controlled Trials (CENTRAL), Medline, and EMBASE...
July 16, 2018: BJOG: An International Journal of Obstetrics and Gynaecology
https://www.readbyqxmd.com/read/30007113/urinary-stress-incontinence-and-other-maternal-outcomes-two-years-after-caesarean-or-vaginal-birth-for-twin-pregnancy-a-multicentre-randomised-trial
#4
Eileen K Hutton, Mary E Hannah, Andrew R Willan, Susan Ross, Alexander C Allen, B Anthony Armson, Amiram Gafni, K S Joseph, Kathryn Mangoff, Arne Ohlsson, J Johanna Sanchez, Elizabeth V Asztalos, Jon F R Barrett
OBJECTIVE: Does planned caesarean compared with planned vaginal birth lower the risk of problematic urinary stress, fecal or flatal incontinence?. DESIGN: Women between 32 0/7 and 38 6/7 weeks gestation with twin pregnancy were randomised to planned caesarean or planned vaginal birth. SETTING: 106 centers in 25 countries. POPULATION: 2305 /2804 enrolled in the study completed questionnaires at two years (82.2%follow up): 1155 in the planned caesarean group, 1150 in the planned vaginal birth group...
July 14, 2018: BJOG: An International Journal of Obstetrics and Gynaecology
https://www.readbyqxmd.com/read/30007106/a-definitive-rct-addressing-the-impact-of-vaginal-birth-on-incontinence
#5
R M Tähtinen, R Cartwright
Stress urinary incontinence is a common condition among women. Although an extensive body of evidence suggests that vaginal delivery increases rates of post-partum stress urinary incontinence compared with caesarean section (Tähtinen RM et al. Eur Urol. 2016;70:148-58) there has been almost an complete lack of adequate prior RCT data. The only previous randomized trial to address this topic is the Term Breech Trial (Hannah M et al. Am J Obstet Gynecol.2004;191:917-27). This article is protected by copyright...
July 14, 2018: BJOG: An International Journal of Obstetrics and Gynaecology
https://www.readbyqxmd.com/read/30007098/core-outcome-set-for-induction-of-labour-trials-what-s-the-expectation
#6
Moeun Son
Induction of labour is one of the most common procedures performed in obstetrics. As such, many clinical trials have been undertaken to try to optimise induction strategies and interventions. Unfortunately, the wide variation in the measuring and reporting of outcomes across induction studies - as well as studies involving different topics - has hampered the process of data synthesis and effective translation into clinical practice. In an effort to mitigate these challenges, there has been a growing call for the development and use of core outcome sets in the field of obstetrics...
July 14, 2018: BJOG: An International Journal of Obstetrics and Gynaecology
https://www.readbyqxmd.com/read/29992731/vaginal-prevalence-of-hpv-infections-in-uterovaginal-aplasia-patients-before-and-after-laparoscopically-assisted-creation-of-a-neovagina-a-prospective-epidemiological-observational-study
#7
K Katharina Rall, Birgitt Schoenfisch, Dorit Schoeller, Diana Stefanescu, Andrina Koelle, Melanie Henes, Markus Huebner, Florin Andrei Taran, Harald Seeger, Angelika Iftner, Thomas Iftner, Sara Yvonne Brucker
OBJECTIVE: To study vaginal as opposed to cervical HPV acquisition with regard to true prevalence, HPV types, and the role of co-factors in virgins and after their sexual debut. DESIGN: Prospective epidemiological observational study. SETTING: University hospital specialized in genital malformations. POPULATION: Women diagnosed with MRKHS and undergoing neovaginoplasty between November 2011 and July 2017. METHODS: This is a prospective study including 186 MRKH patients before and after sexual debut...
July 10, 2018: BJOG: An International Journal of Obstetrics and Gynaecology
https://www.readbyqxmd.com/read/29989319/investigation-before-implementation
#8
Brett D Einerson
Dr. Archie Cochrane is widely considered to be the first great champion of evidence-based medicine. His now famous 1971 book bemoaned the absence of evidence supporting many of the medical interventions widely practiced at the time. [Effectiveness and Efficiency, Cochrane] He urged physicians to measure "the benefit and the cost to the population of a particular type of activity," and to use this data to guide medical decisions. This article is protected by copyright. All rights reserved.
July 10, 2018: BJOG: An International Journal of Obstetrics and Gynaecology
https://www.readbyqxmd.com/read/29989298/asparaginase-like-protein-1-expression-in-curettage-independently-predicts-lymph-node-metastasis-in-endometrial-carcinoma-a-multicenter-study
#9
Tina Fonnes, Jone Trovik, Per-Henrik D Edqvist, Kristine E Fasmer, Janusz Marcickiewicz, Solveig Tingulstad, Anne C Staff, Line Bjørge, Frederic Amant, Ingfrid S Haldorsen, Henrica Mj Werner, Lars A Akslen, Ingvild L Tangen, Camilla Krakstad
OBJECTIVE: Correct preoperative identification of high-risk patients is important to optimize surgical treatment and improve survival. We wanted to explore if Asparaginase-like protein 1 (ASRGL1) expression in curettage could predict lymph node metastases and poor outcome, potentially improving preoperative risk stratification. DESIGN: Multicenter study. SETTING: Ten hospitals in Norway, Sweden and Belgium. POPULATION: Women diagnosed with endometrial carcinoma...
July 10, 2018: BJOG: An International Journal of Obstetrics and Gynaecology
https://www.readbyqxmd.com/read/29989296/male-factor-infertility-an-opportunity-to-investigate-individual-and-family-health
#10
Sorena Keihani, Brent Hanson, James M Hotaling
Male infertility affects at least half of infertile couples, either as the sole factor or a contributing element. Despite its common nature, men seek infertility care at a lower rate than women. About 50% of men experiencing infertility do not seek professional help and up to a quarter of couples seeking infertility treatment do not complete a male factor evaluation. This article is protected by copyright. All rights reserved.
July 10, 2018: BJOG: An International Journal of Obstetrics and Gynaecology
https://www.readbyqxmd.com/read/29981523/development-of-a-core-outcome-set-for-trials-on-induction-of-labour-cosiol-an-international-multi-stakeholder-delphi-study
#11
Francois Dos Santos, Stephanie Drymiotou, Alba Antequera, Ben W Mol, Christopher Gale, Declan Devane, Janneke Van't Hooft, Mark J Johnson, Matthew Hogg, Shakila Thangaratinam
OBJECTIVE: To develop a set of core outcomes to be minimally reported in trials on induction of labour. DESIGN: Two-round Delphi survey and consensus meeting. POPULATION: Four Stakeholder groups: midwives, obstetricians, neonatologists, and women's representatives. METHODS: Protocol registered with COMET (registration number: 695). Stakeholders rated reported outcomes for importance (1-limited to 9-critical). The median rating of each outcome was calculated...
July 7, 2018: BJOG: An International Journal of Obstetrics and Gynaecology
https://www.readbyqxmd.com/read/29978593/patient-initiated-follow-up-affects-fear-of-recurrence-and-health-care-use-a-randomized-trial-in-early-stage-endometrial-cancer
#12
M M Jeppesen, P T Jensen, D G Hansen, R D Christensen, O Mogensen
OBJECTIVE: To test the hypothesis that patient-initiated follow-up reduces fear of cancer recurrence (FCR) and health care use when compared to traditional hospital-based follow-up. DESIGN: Pragmatic, multi-centre randomized trial. SETTING: Four Danish departments of gynaecology between May 2013 and May 2016. POPULATION: 156 women diagnosed with International Federation of Gynaecology and Obstetrics (FIGO) stage I low-intermediate risk endometrial carcinoma METHODS: Women allocated to the control group attended hospital-based follow-up consisting of regular out-patient visits for three years after primary treatment...
July 6, 2018: BJOG: An International Journal of Obstetrics and Gynaecology
https://www.readbyqxmd.com/read/29978556/collect-a-collaborative-database-for-pregnancy-and-placental-research-studies-worldwide
#13
Jenny E Myers, Leslie Myatt, James M Roberts, Christopher W G Redman
The related pregnancy complications, pre-eclampsia, fetal growth restriction (FGR) and preterm birth persist as leading causes of maternal and perinatal death and long term morbidity. Whilst the impact of these conditions is significant in high income countries, the burden of these diseases falls disproportionately on low and middle income countries (LMICS). Whilst our understanding of the underlying pathophysiology of the obstetrical syndromes, pre-eclampsia, FGR and preterm birth has progressed, the development of new treatments and preventative strategies has slowed, with very few new interventions successfully translating into clinical practice...
July 6, 2018: BJOG: An International Journal of Obstetrics and Gynaecology
https://www.readbyqxmd.com/read/29978553/recurrence-of-pre-eclampsia-and-the-risk-of-future-hypertension-and-cardiovascular-disease-a-systematic-review-and-meta-analysis
#14
Laura Brouwers, Alida J van der Meiden-van Roest, Claudia Savelkoul, Tatjana E Vogelvang, A Titia Lely, Arie Franx, Bas B van Rijn
BACKGROUND: women with a history of hypertensive disorders, including pre-eclampsia during pregnancy, have a two-to-five fold increased risk of cardiovascular disease (CVD). In 15% of women pre-eclampsia recurs in the following pregnancy. OBJECTIVES: to evaluate all evidence on the future risk of developing hypertension and CVD after multiple pregnancies complicated by pre-eclampsia compared with pre-eclampsia in a single pregnancy followed by normal subsequent pregnancy...
July 6, 2018: BJOG: An International Journal of Obstetrics and Gynaecology
https://www.readbyqxmd.com/read/29978539/endometrial-cancer-follow-up-finding-the-confidence-to-let-go
#15
Jo Morrison
Follow up after endometrial cancer lacks a supporting evidence base and "the less there is to justify a traditional custom, the harder it is to get rid of it" (Twain M. The Adventures of Tom Sawyer. 1876). A number of factors drive routine follow up including; desire to improve outcomes; psychological benefits to both patient and clinician; and financial gain. However, there are costs to follow up for patients and health systems. We need to critically evaluate effectiveness and cost-effectiveness of follow up strategies in endometrial cancer...
July 6, 2018: BJOG: An International Journal of Obstetrics and Gynaecology
https://www.readbyqxmd.com/read/29953717/risk-of-hypertension-after-hysterectomy-a-population-based-study
#16
Dah-Ching Ding, I-Ju Tsai, Chung Y Hsu, Jen-Hung Wang, Shinn-Zong Lin, Fung-Chang Sung
OBJECTIVE: Hysterectomy is the second most common surgery performed for mainly benign uterine pathologies in females. The association between hysterectomy and the subsequent risk of hypertension remains controversial. This study investigated the risk of developing hypertension in women who had a hysterectomy. DESIGN: Population-based retrospective cohort study. SETTING: We used the Taiwan National Health Insurance Research Database with claims data of 1 million randomly selected insured individuals...
June 28, 2018: BJOG: An International Journal of Obstetrics and Gynaecology
https://www.readbyqxmd.com/read/29952111/re-the-incidence-characteristics-managements-and-outcomes-of-anaphylaxis-in-pregnancy-a-population-based-descriptive-study-latex-anaphylaxis-in-pregnancy-gone-or-forgotten
#17
LETTER
Ilai Ronel, Carolyn F Weiniger, Nadav Levy
No abstract text is available yet for this article.
June 27, 2018: BJOG: An International Journal of Obstetrics and Gynaecology
https://www.readbyqxmd.com/read/29952063/authors-reply-re-the-incidence-characteristics-management-and-outcomes-of-anaphylaxis-in-pregnancy-a-population-based-descriptive-study
#18
LETTER
Stephen J McCall, Kathryn J Bunch, Peter Brocklehurst, Rhiannon D'Arcy, Kim Hinshaw, Jennifer J Kurinczuk, D Nuala Lucas, Benjamin Stenson, Derek Tuffnell, Marian Knight
No abstract text is available yet for this article.
June 27, 2018: BJOG: An International Journal of Obstetrics and Gynaecology
https://www.readbyqxmd.com/read/29940089/abnormal-vaginal-bleeding-in-women-of-reproductive-age-treated-with-edoxaban-or-warfarin-for-venous-thromboembolism-a-post-hoc-analysis-of-the-hokusai-vte-study
#19
Luuk J J Scheres, Marjolein P A Brekelmans, Walter Ageno, Cihan Ay, Harry R Büller, Sabine Eichinger, Barbara A Hutten, Frederikus A Klok, Saskia Middeldorp, Karen Schreiber, Ksenija Stach, Marc Blondon, Aurélien Delluc
OBJECTIVE: to investigate the characteristics and outcome of abnormal vaginal bleeding in women receiving edoxaban or warfarin for treatment of venous thromboembolism (VTE). DESIGN AND SETTING: post-hoc analysis of the Hokusai-VTE study, a multicentre, randomized, double-blind trial comparing edoxaban with for acute symptomatic VTE. POPULATION: women below 50 years receiving edoxaban or warfarin for treatment of VTE. METHODS: we collected data on diagnostic measures, treatment and clinical outcome of abnormal vaginal bleeding events...
June 25, 2018: BJOG: An International Journal of Obstetrics and Gynaecology
https://www.readbyqxmd.com/read/29940085/measurements-of-a-normal-vulva-in-women-aged-15-84-a-cross-sectional-prospective-single-centre-study
#20
Anne Kreklau, Inês Vaz, Florian Oehme, Fabienne Strub, Ruth Brechbühl, Corina Christmann, Andreas Günthert
OBJECTIVE: Accurate and detailed description of a "normal vulva" is rare, even though few studies dealt with the topic of normal measurements of parts of the external female genitalia. This leads to a situation with a wide range of existing diagnoses concerning "normal" vulvar morphology. DESIGN: Cross-sectional prospective single center study. SETTING: From August 2015 to April 2017 we included 657 women in our gynecological and uro-gynecological outpatient clinic of the Cantonal Hospital Lucerne...
June 25, 2018: BJOG: An International Journal of Obstetrics and Gynaecology
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