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International Journal of Colorectal Disease

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https://www.readbyqxmd.com/read/28634703/isoperistaltic-versus-antiperistaltic-side-to-side-anastomosis-after-right-laparoscopic-hemicolectomy-for-cancer-isovanti-trial-study-protocol-for-a-randomised-clinical-trial
#1
N Ibañez, J Abrisqueta, J Luján, Q Hernández, P Parrilla
BACKGROUND: It is believed that loosing ileocecal valve is well tolerated in patients who do not have short bowel syndrome or Crohn disease. From the hypothesis of colonic peristalsis and transit is regulated by that ileocecal valvular mechanism, we try to find out if the creation of a new pseudo-valvular mechanism as antiperistaltic anastomosis could be considered after right hemicolectomy can cause any short- or long-term changes in gastrointestinal habits. PURPOSE: The purpose of the study at primary endpoint is to compare early (occurring within 30 days of surgery) and late (occurring during the follow-up) postoperative complications between both groups The purpose of the study at secondary endpoint is to compare intraoperative and postoperative events between experimental and control groups in terms of operating time, first oral tolerance day, first flatus and faeces, length of hospital stay and orocecal transit; comparing rates of gastrointestinal life quality and comparing mortality rates between both groups...
June 21, 2017: International Journal of Colorectal Disease
https://www.readbyqxmd.com/read/28555444/diverticulitis-recurrence-after-percutaneous-abscess-drainage
#2
REVIEW
Tarek Jalouta, Nezar Jrebi, Martin Luchtefeld, James W Ogilvie
PURPOSE: Recurrent diverticulitis has been reported in 30-50% of patients who recover from an episode of diverticular-associated abscess. Our aim was to review the outcomes of patients who underwent non-operative management after percutaneous drainage (PD) of colonic diverticular abscess. METHODS: All patients with a diverticular-associated abscess were identified between 2001 and 2012. Individual charts were queried for peri-procedural data and follow-up. The most recent follow-up data were acquired via the electronic medical record or telephone call...
May 30, 2017: International Journal of Colorectal Disease
https://www.readbyqxmd.com/read/28540599/erratum-to-primary-vs-delayed-perineal-proctectomy-there-is-no-free-lunch
#3
Vitaliy Poylin, Thomas Curran, Daniel Alvarez, Deborah Nagle, Thomas Cataldo
No abstract text is available yet for this article.
May 24, 2017: International Journal of Colorectal Disease
https://www.readbyqxmd.com/read/28536898/impact-of-tissue-adhesives-on-the-prevention-of-anastomotic-leakage-of-colonic-anastomoses-an-in-vivo-study
#4
Konstantinos A Vakalopoulos, Joanna W A M Bosmans, Kevin W Y van Barneveld, Ruben R M Vogels, Geesien S A Boersema, Zhouqiao Wu, Marion J J Gijbels, Johannes Jeekel, Gert-Jan Kleinrensink, Nicole D Bouvy, Johan F Lange
BACKGROUND: Tissue adhesives (TA) may be useful to strengthen colorectal anastomoses, thereby preventing anastomotic leakage (AL). Previous studies have identified cyanoacrylate (CA) TAs as the most promising colonic anastomotic sealants. This study investigates the protective effects of sealing colonic anastomoses with various CAs. MATERIALS AND METHODS: Fifty-five Wistar rats underwent laparotomy and transection of the proximal colon. An anastomosis was created with 4 interrupted sutures followed by either application of Histoacryl Flexible, Omnex, Glubran 2, or no TA seal...
May 23, 2017: International Journal of Colorectal Disease
https://www.readbyqxmd.com/read/28534070/total-abdominal-colectomy-vs-restorative-total-proctocolectomy-as-the-initial-approach-to-medically-refractory-ulcerative-colitis
#5
Jinyu Gu, Luca Stocchi, Jeanie Ashburn, Feza H Remzi
PURPOSE: There is scant data assessing the consequences of staging restorative proctocolectomy for ulcerative colitis. The aim of the study is to compare outcomes of initial vs. staged restorative proctocolectomy. METHODS: Patients completing restorative proctocolectomy, including ileostomy reversal, during 2006-2012 were identified from an IRB-approved database. Demographics, treatment variables, and perioperative outcomes were assessed. RESULTS: Out of 521 patients, 322 (62%) underwent initial total abdominal colectomy before restorative proctectomy...
May 22, 2017: International Journal of Colorectal Disease
https://www.readbyqxmd.com/read/28526942/development-of-a-new-risk-nomogram-of-perioperative-major-adverse-cardiac-events-for-chinese-patients-undergoing-colorectal-carcinoma-surgery
#6
Juhong Zhang, Ying Xiao, Daya Yang, Xiaodong Zhuang, Ling Wang, Xiuren Gao, Zhibin Huang
PURPOSE: The purpose of this study is to create a new risk nomogram to predict perioperative major adverse cardiac events in patients undergoing colorectal carcinoma surgery. METHODS: A total of 1899 patients who underwent colorectal carcinoma surgery at a tertiary teaching hospital in China between 2007 and 2012 were recruited. Logistic regression analysis was used to define risk factors for major adverse cardiac events. A nomogram-predicting model was built based on the logistic regression model and discrimination was tested by receiver operating characteristic curves...
May 19, 2017: International Journal of Colorectal Disease
https://www.readbyqxmd.com/read/28523473/young-colorectal-cancer-patients-often-present-too-late
#7
Jia-Hao Law, Frederick H Koh, Ker-Kan Tan
PURPOSE: Current screening and health education strategies on colorectal cancer (CRC) remain focused on individuals >50 years old. However, CRC in young adults is not uncommon. This paper aims to explore how CRC presents in young adults and their clinical outcomes. METHODS: All patients aged <50 years diagnosed with CRC from January 2007 to December 2015 were reviewed. Patient demographics, clinical symptoms, and outcomes of treatment were collected. RESULTS: Of 1367 patients diagnosed with CRC, 154 (11...
May 18, 2017: International Journal of Colorectal Disease
https://www.readbyqxmd.com/read/28501944/sociodemographic-predictors-of-participation-in-colorectal-cancer-screening
#8
Ulrik Deding, Anna Sharon Henig, Ann Salling, Christian Torp-Pedersen, Henrik Bøggild
PURPOSE: Colorectal cancer screening by inviting citizens to complete a test for blood in faeces was initiated in Denmark in 2014. We have examined sociodemographic predictors that influence participation to identify factors that could be targeted to increase compliance. METHODS: National registers were used to link data on invitations for colorectal cancer screening in Denmark from 2014 to 2015. Region of residence, age, gender, immigration status, income, educational level and marital status were identified...
May 13, 2017: International Journal of Colorectal Disease
https://www.readbyqxmd.com/read/28501943/protocol-for-the-development-of-a-core-outcome-set-cos-for-hemorrhoidal-disease-an-international-delphi-study
#9
R R van Tol, J Melenhorst, C D Dirksen, L P S Stassen, S O Breukink
PURPOSE: Over the last decade, many studies were performed regarding treatment options for hemorrhoidal disease. Randomised controlled trials (RCTs) should have well-defined primary and secondary outcomes. However, the reported outcome measures are numerous and diverse. The heterogeneity of outcome definition in clinical trials limits transparency and paves the way for bias. The development of a core outcome set (COS) helps minimizing this problem. A COS is an agreed minimum set of outcomes that should be measured and reported in all clinical trials of a specific disease...
May 13, 2017: International Journal of Colorectal Disease
https://www.readbyqxmd.com/read/28497404/sexual-dysfunction-following-rectal-cancer-surgery
#10
REVIEW
V Celentano, R Cohen, J Warusavitarne, O Faiz, M Chand
INTRODUCTION: Sexual and urological problems after surgery for rectal cancer are common, multifactorial, inadequately discussed, and untreated. The urogenital function is dependent on dual autonomic sympathetic and parasympathetic innervation, and four key danger zones exist that are at risk for nerve damage during colorectal surgery: one of these sites is in the abdomen and three are in the pelvis. The aim of this study is to systematically review the epidemiology of sexual dysfunction following rectal cancer surgery, to describe the anatomical basis of autonomic nerve-preserving techniques, and to explore the scientific evidence available to support the laparoscopic or robotic approach over open surgery...
May 11, 2017: International Journal of Colorectal Disease
https://www.readbyqxmd.com/read/28497403/locally-advanced-rectal-cancer-predicting-non-responders-to-neoadjuvant-chemoradiotherapy-using-apparent-diffusion-coefficient-textures
#11
Ming Liu, Han Lv, Li-Heng Liu, Zheng-Han Yang, Er-Hu Jin, Zhen-Chang Wang
PURPOSE: The purpose of the study is to evaluate whether apparent diffusion coefficient (ADC) textures could identify patient with locally advanced rectal cancer (LARC) who would not respond to neoadjuvant chemoradiotherapy (NCRT). METHOD: Twenty-six patients who underwent MRI including diffusion-weighted imaging at a 3.0 T system before NCRT were enrolled. Texture analysis of pre-therapy ADC mapping was carried out, and a total of 133 ADC textures as well as routine mean ADC value of the primary tumor were extracted for each patient...
May 11, 2017: International Journal of Colorectal Disease
https://www.readbyqxmd.com/read/28497402/impact-of-resection-versus-no-resection-of-the-primary-tumor-on-survival-in-patients-with-colorectal-cancer-and-synchronous-unresectable-metastases-protocol-for-a-randomized-multicenter-study-cr4
#12
Sebastiano Biondo, Ricardo Frago, Esther Kreisler, Eloy Espin-Basany
PURPOSE: The purpose of this study was to determine whether patients diagnosed with colorectal cancer and synchronous unresectable metastases (stage IV) can benefit from resection of the primary tumor in terms of an improvement in cancer-specific survival. METHODS: Stage IV colorectal cancer patients are eligible for inclusion in a randomized multicenter study carried out in 22 hospitals throughout Spain. Exclusion criteria are rectal tumors below 12 cm from the anal verge or locally advanced tumors, multiple bone or central nervous system metastases, and history of another primary cancer...
May 11, 2017: International Journal of Colorectal Disease
https://www.readbyqxmd.com/read/28493008/role-of-family-history-and-tumor-location-on-prognosis-of-patients-with-colorectal-cancer-and-synchronous-metastases
#13
Colloca Giuseppe, Venturino Antonella
BACKGROUND/AIMS: Family history of colorectal cancer and tumor location along colon-rectum have been reported as prognostic factors. The aim of the current study is to analyze the role of both on overall survival in a series of patients with metastatic colorectal cancer with synchronous metastases. METHODS: A retrospective mono-institutional analysis has been performed on patients, who received chemotherapy from 2004 to 2008. A Cox proportional-hazards regression was used to calculate hazard ratio (HR) for death, after adjustment for other variables (tumor metastasectomy, number of organs involved with metastases, number of anti-neoplastic drugs, age, sex, tumor grade, baseline CEA)...
May 10, 2017: International Journal of Colorectal Disease
https://www.readbyqxmd.com/read/28484832/accuracy-of-routinely-collected-comorbidity-data-in-patients-undergoing-colectomy-a-retrospective-study
#14
Shahin Hajibandeh, Shahab Hajibandeh, Roger Deering, Dearbhla McEleney, John Guirguis, Sarah Dix, Abdelhakem Sreh, Afsana Kausar
OBJECTIVES: This paper aimed to determine the baseline accuracy, sensitivity, specificity, positive predictive value (PPV), and negative predictive value (NPV) of routinely collected comorbidity data in patients undergoing any types of colectomy. METHODS: All patients aged >18 who underwent right hemicolectomy, left hemicolectomy, sigmoid colectomy, subtotal colectomy, or total colectomy between 1 January 2015 and 1 November 2016 were identified. The following comorbidities were considered: hypertension, ischemic heart disease (IHD), diabetes, asthma, chronic obstructive pulmonary disease (COPD), cerebrovascular disease (CVD), chronic kidney disease (CKD), and hypercholesterolemia...
May 8, 2017: International Journal of Colorectal Disease
https://www.readbyqxmd.com/read/28478571/primary-vs-delayed-perineal-proctectomy-there-is-no-free-lunch
#15
Vitaliy Poylin
PURPOSE: Perineal wound complications associated with anorectal excision are associated with prolonged wound healing and readmission. In order to avoid these problems, the surgeon may choose to leave the anorectum in situ. The purpose of this study is to compare complications and outcomes after primary vs. delayed anorectum removal. METHODS: A retrospective review of all patients undergoing proctectomy or proctocolectomy with permanent stoma between 2004 and 2014 in a single tertiary institution was conducted...
May 6, 2017: International Journal of Colorectal Disease
https://www.readbyqxmd.com/read/28474261/letter-to-the-editor-regarding-colorectal-surgery-and-surgical-site-infection-is-a-change-of-attitude-necessary
#16
LETTER
Saeed Shoar, Sergio Ibarra, Alberto Gonzalez, Daniel P Geisler
No abstract text is available yet for this article.
May 4, 2017: International Journal of Colorectal Disease
https://www.readbyqxmd.com/read/28474260/the-role-of-hepatic-enzymes-in-crohn-s-disease
#17
LETTER
Davide Giuseppe Ribaldone, Marco Astegiano, Rinaldo Pellicano
No abstract text is available yet for this article.
May 4, 2017: International Journal of Colorectal Disease
https://www.readbyqxmd.com/read/28444508/study-protocol-on-the-role-of-intestinal-microbiota-in-colorectal-cancer-treatment-a-pathway-to-personalized-medicine-2-0
#18
R Aarnoutse, J M P G M de Vos-Geelen, J Penders, E G Boerma, F A R M Warmerdam, B Goorts, S W M Olde Damink, Z Soons, S S M Rensen, M L Smidt
PURPOSE: Investigate in patients with metastatic and/or irresectable colorectal cancer treated with systemic treatment with capecitabine or TAS-102 whether: 1. Intestinal microbiota composition can act as a predictor for response. 2. Intestinal microbiota composition changes during systemic treatment and its relation to chemotoxicity. BACKGROUND: Gut microbiota and host determinants evolve in symbiotic and dependent relationships resulting in a personal ecosystem...
April 25, 2017: International Journal of Colorectal Disease
https://www.readbyqxmd.com/read/28444507/heuristics-and-bias-in-rectal-surgery
#19
Ewan MacDermid, Christopher J Young, Susan J Moug, Robert G Anderson, Heather L Shepherd
PURPOSE: Deciding to defunction after anterior resection can be difficult, requiring cognitive tools or heuristics. From our previous work, increasing age and risk-taking propensity were identified as heuristic biases for surgeons in Australia and New Zealand (CSSANZ), and inversely proportional to the likelihood of creating defunctioning stomas. We aimed to assess these factors for colorectal surgeons in the British Isles, and identify other potential biases. METHODS: The Association of Coloproctology of Great Britain and Ireland (ACPGBI) was invited to complete an online survey...
April 25, 2017: International Journal of Colorectal Disease
https://www.readbyqxmd.com/read/28444506/preoperative-risk-factors-for-prolonged-postoperative-ileus-after-colorectal-resection
#20
Albert M Wolthuis, Gabriele Bislenghi, Maarten Lambrecht, Steffen Fieuws, Anthony de Buck van Overstraeten, Guy Boeckxstaens, André D'Hoore
PURPOSE: Prolonged postoperative ileus (PPOI) after colorectal resection significantly impacts patients' recovery and hospital stay. Because treatment options for PPOI are limited, it is necessary to focus on prevention strategies. The aim of this study is to investigate risk factors associated with PPOI in patients undergoing colorectal surgery. METHODS: Data from all consecutive patients who underwent colorectal resection in our department were retrospectively analyzed from a prospective database over a 9-month period...
April 25, 2017: International Journal of Colorectal Disease
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