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International Journal of Colorectal Disease

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https://www.readbyqxmd.com/read/28213624/oligometastatic-colorectal-cancer-is-single-site-bony-colorectal-metastasis-a-treatable-condition
#1
Noel Cassar, Adrian Ben Cresswell, Brendan Moran
INTRODUCTION: A potentially resectable bony metastasis in the context of oligometastatic colorectal cancer is uncommon. Bony metastases are usually considered a late event with poor prognosis and generally associated with liver and/or lung metastases. INDEX CASE: A previously healthy 33-year-old gentleman, with no family history of colorectal cancer, presented with rectal bleeding and at colonoscopy had a biopsy-proven adenocarcinoma of the rectum, 7 cm from the anal verge...
February 17, 2017: International Journal of Colorectal Disease
https://www.readbyqxmd.com/read/28210856/the-effect-of-metformin-on-the-recurrence-of-colorectal-adenoma-in-diabetic-patients-with-previous-colorectal-adenoma
#2
Min Seok Han, Hyun Jung Lee, Soo Jung Park, Sung Pil Hong, Jae Hee Cheon, Won Ho Kim, Tae Il Kim
PURPOSE: Existing studies suggest that metformin lowers the risk and mortality of colorectal cancer. However, the effect of metformin on the suppression and prevention of colorectal adenomas is not clear. The aim of this study was to evaluate the effect of metformin on the recurrence of colorectal adenoma in diabetic patients with previous colorectal adenoma. METHODS: Among 423 diabetic patients who underwent surveillance colonoscopy after resection of colorectal adenoma between 2005 and 2011, 257 patients were retrospectively reviewed...
February 16, 2017: International Journal of Colorectal Disease
https://www.readbyqxmd.com/read/28210855/lymph-node-retrieval-in-colorectal-cancer-determining-factors-and-prognostic-significance
#3
Johannes Betge, Lars Harbaum, Marion J Pollheimer, Richard A Lindtner, Peter Kornprat, Matthias P Ebert, Cord Langner
PURPOSE: The study aimed to analyze clinicopathological factors that determine the extent of lymph node retrieval and to evaluate its prognostic impact in patients with colorectal cancer (CRC). METHODS: The number of retrieved lymph nodes was analyzed in 381 CRC specimens. Lymph node count was related to different clinicopathological variables by binary logistic regression. Progression-free survival (PFS) and cancer-specific survival (CSS) were determined using the Kaplan-Meier method and Cox regression models...
February 16, 2017: International Journal of Colorectal Disease
https://www.readbyqxmd.com/read/28210854/comparison-of-histopathology-and-real-time-polymerase-chain-reaction-rt-pcr-for-detection-of-mycobacterium-tuberculosis-in-fistula-in-ano
#4
Pankaj Garg
PURPOSE: Histopathology is commonly used to diagnose tuberculosis in fistula-in-ano. The aim was to compare the sensitivity of polymerase chain reaction and histopathology in detecting tuberculosis in fistula-in-ano. METHODS: The histopathology and polymerase chain-reaction of tissue (fistula tract) was done in all the consecutive operated cases. When pus sample was also available, polymerase chain reaction-pus was also done RESULTS: Three hundred forty seven samples (179 patients) were tested over 2 years (median 6...
February 16, 2017: International Journal of Colorectal Disease
https://www.readbyqxmd.com/read/28210853/the-yet-to-be-discovered-mechanism-of-anastomotic-leakage-comment-to-lack-of-evidence-for-tissue-hypoxia-as-a-contributing-factor-in-anastomotic-leak-following-colon-anastomosis-and-segmental-devascularization-in-rats
#5
LETTER
https://www.readbyqxmd.com/read/28210852/treatment-of-rectovaginal-fistula-with-gracilis-muscle-flap-transposition-long-term-follow-up
#6
Seong Oh Park, Ki Yong Hong, Kyo Joo Park, Hak Chang, Jin Yong Shin, Seung-Yong Jeong
PURPOSE: Rectovaginal fistulas are difficult to treat completely, especially when patients present with a history of multiple surgeries and radiation therapy. We aimed to evaluate the efficacy of gracilis muscle flap transposition to treat rectovaginal fistula. METHODS: We performed a retrospective chart review of all gracilis muscle transposition cases and other procedures between January 2009 and July 2016. RESULTS: Total 53 cases were reviewed...
February 16, 2017: International Journal of Colorectal Disease
https://www.readbyqxmd.com/read/28210851/in-vivo-and-ex-vivo-sentinel-node-mapping-does-not-identify-the-same-lymph-nodes-in-colon-cancer
#7
Helene Schou Andersen, Astrid Louise Bjørn Bennedsen, Stefan Kobbelgaard Burgdorf, Jens Ravn Eriksen, Susanne Eiholm, Anders Toxværd, Lene Buhl Riis, Jacob Rosenberg, Ismail Gögenur
INTRODUCTION: Identification of lymph nodes and pathological analysis is crucial for the correct staging of colon cancer. Lymph nodes that drain directly from the tumor area are called "sentinel nodes" and are believed to be the first place for metastasis. The purpose of this study was to perform sentinel node mapping in vivo with indocyanine green and ex vivo with methylene blue in order to evaluate if the sentinel lymph nodes can be identified by both techniques. METHODS: Patients with colon cancer UICC stage I-III were included from two institutions in Denmark from February 2015 to January 2016...
February 16, 2017: International Journal of Colorectal Disease
https://www.readbyqxmd.com/read/28204867/right-versus-left-laparoscopic-colectomy-for-colon-cancer-does-side-make-any-difference
#8
Juan P Campana, Pablo A Pellegrini, Gustavo L Rossi, Guillermo Ojea Quintana, Ricardo E Mentz, Carlos A Vaccaro
PURPOSE: To compare the intraoperative and postoperative outcomes between right laparoscopic colectomy (RLC) and left laparoscopic colectomy (LLC) for colon cancer. METHOD: Patients who underwent elective RLC or LLC for colon cancer between January 2004 and December 2014 were identified and elected for a retrospective analysis. Primary outcomes were technical difficulty (including operative time, intraoperative complications, and conversion rate) and postoperative outcome (including postoperative complications, length of hospital stay, reinterventions, readmissions, and mortality)...
February 15, 2017: International Journal of Colorectal Disease
https://www.readbyqxmd.com/read/28194494/college-inflammatory-bowel-disease-c-ibd-day-a-targeted-approach-to-shared-decision-making-in-college-age-students-with-ibd-a-2-year-pilot-project
#9
Kofi Clarke, Mohammad Bilal, Heitham Abdul-Baki, Paul Lebovitz, Sandra El-Hachem
BACKGROUND: Adherence to treatment is a key therapeutic goal in chronic disorders including diabetes, inflammatory bowel disease (IBD), and hypertension. Non-adherence has been associated with increased health care costs. Previous studies have evaluated adherence to treatment in inflammatory bowel disease, as well as predictors of non-adherence. Higher belief of necessity for medications and membership of IBD patient organizations have been associated with higher medication adherence...
February 13, 2017: International Journal of Colorectal Disease
https://www.readbyqxmd.com/read/28190102/the-positive-impact-of-surgical-quality-control-on-adequate-lymph-node-harvest-by-standardized-laparoscopic-surgery-and-national-quality-assessment-program-in-colorectal-cancer
#10
Daeyoun David Won, Sung Bong Choi, Yoon Suk Lee, Seong Taek Oh, Jun Gi Kim, In Kyu Lee
PURPOSE: We aimed to present the factors associated with lymph node harvest (LNH) and seek whether surgical quality control measures can improve LNH. METHODS: From a prospectively collected data at a single institution, 874 CRC patients who underwent curative surgery between 2004 and 2013 were included. Factor and survival analyses were performed regarding LNH. Subgroup analysis was performed according to LNH group (LNH ≥ 12 vs LNH < 12) and year of surgery (2004-2008, 2009-2011, and 2012-2013 group)...
February 11, 2017: International Journal of Colorectal Disease
https://www.readbyqxmd.com/read/28190101/morphologic-change-of-the-psoas-muscle-as-a-surrogate-marker-of-sarcopenia-and-predictor-of-complications-after-colorectal-cancer-surgery
#11
Marie Hanaoka, Masamichi Yasuno, Megumi Ishiguro, Shinichi Yamauchi, Akifumi Kikuchi, Michiyo Tokura, Toshiaki Ishikawa, Eiji Nakatani, Hiroyuki Uetake
PURPOSE: Sarcopenia is reported to be associated with complications after surgery. However, there is no established optimal parameter to determine sarcopenia affecting surgical outcome. This study investigated whether morphologic change of the psoas muscle (MPM) reflects sarcopenia and could be a predictor of complications after colorectal cancer surgery. METHODS: Colorectal cancer patients who underwent primary tumor resection with anastomosis between 2015 and 2016 were analyzed...
February 11, 2017: International Journal of Colorectal Disease
https://www.readbyqxmd.com/read/28188417/the-efficacy-of-endoscopic-submucosal-dissection-for-colorectal-tumors-extending-to-the-dentate-line
#12
Satohiro Matsumoto, Hirosato Mashima
PURPOSE: Although endoscopic submucosal dissection (ESD) is becoming the mainstay of the treatment strategies, rather than surgical treatment, for colorectal tumors extending to the dentate line, ESD is technically more difficult. This study was aimed at assessing the usefulness of ESD for the treatment of colorectal tumors extending to the dentate line. METHODS: This study included 531 patients with colorectal tumors who underwent colorectal ESD between 2008 and 2015...
February 10, 2017: International Journal of Colorectal Disease
https://www.readbyqxmd.com/read/28185004/an-18-month-study-of-the-effects-of-ibd-symptomatology-and-emotion-regulation-on-depressed-mood
#13
Inês A Trindade, Cláudia Ferreira, Mariana Moura-Ramos, José Pinto-Gouveia
PURPOSE: Depressive symptomatology in IBD patients is known to predict disease activity, which, in turn, can increase depressive symptoms in perpetuating a cycle between depression and IBD symptomatology. The mechanisms that contribute to the relationship between disease activity and depressive symptoms are not clearly investigated yet. Since emotion regulation has been considered particularly relevant to define the impact of adverse experiences on different outcomes, the current study aimed to examine the longitudinal influence of two maladaptive emotion regulation processes, cognitive fusion and brooding, on the association between disease activity and depressed mood...
February 9, 2017: International Journal of Colorectal Disease
https://www.readbyqxmd.com/read/28185003/incorporation-of-serum-carcinoembryonic-antigen-levels-into-the-prognostic-grouping-system-of-colon-cancer
#14
Heita Ozawa, Kenjiro Kotake, Miki Hosaka, Akira Hirata, Yusuke Nakagawa, Shin Fujita, Kenichi Sugihara
PURPOSE: This study aimed to clarify the significance of preoperative serum carcinoembryonic antigen (CEA) on disease-free survival (DFS) in colon cancer and propose a new prognostic grouping system. METHODS: A multiinstitutional retrospective cohort of 7296 colon cancer patients who underwent R0 surgery between 1997 and 2006 was analyzed. We stratified preoperative serum CEA values into three categories (C-stages): C0 (normal CEA), C1A (up to double the cutoff value), and C1B (more than double the cutoff value) and stratified each TNM stage by C-stage...
February 9, 2017: International Journal of Colorectal Disease
https://www.readbyqxmd.com/read/28176005/prognosis-of-video-assisted-thoracoscopic-pulmonary-metastasectomy-in-patients-with-colorectal-cancer-lung-metastases-an-analysis-of-154-cases
#15
Fenghao Sun, Li Chen, Mengkun Shi, Xiaodong Yang, Ming Li, Xinyu Yang, Xiyu Dai, Cheng Zhan, Yu Shi, Qun Wang
PURPOSE: Video-assisted thoracoscopic surgery (VATS) is widely used in thoracic surgery and increasingly applied to pulmonary metastasectomy. The purpose of this study was to identify prognostic factors of patients undergoing VATS pulmonary metastasectomy from colorectal cancer (CRC). METHODS: Between January 2005 and June 2015, a total of 154 patients underwent VATS pulmonary metastasectomy from CRC. Patient demographic data and characteristics of the primary tumor and pulmonary metastasis were analyzed to identify factors significantly correlated with prognosis...
February 7, 2017: International Journal of Colorectal Disease
https://www.readbyqxmd.com/read/28161731/aspecific-ileitis-crohn-s-disease-or-not-crohn-s-disease-a-prospective-study
#16
Cristina Bezzio, Ilaria Arena, Massimo Devani, Barbara Omazzi, Gianpiero Manes, Simone Saibeni
PURPOSE: It is not clear whether aspecific ileitis may represent an early manifestation or a milder variant of Crohn's disease or not. The aim of this study was to evaluate the clinical outcomes of aspecific ileitis. METHODS: Subjects with at least one of the following signs at retrograde ileoscopy: erythema, nodularity, aftae, erosions, and ulcers were considered. They should not have had defined gastrointestinal disease, biochemical signs of inflammation, use of drugs, celiac disease, and intestinal infectious disease...
February 4, 2017: International Journal of Colorectal Disease
https://www.readbyqxmd.com/read/28144745/intraoperative-colonoscopy-for-the-assessment-and-prevention-of-anastomotic-leakage-in-low-anterior-resection-for-rectal-cancer
#17
Seung Yoon Yang, Jeonghee Han, Yoon Dae Han, Min Soo Cho, Hyuk Hur, Kang Young Lee, Nam Kyu Kim, Byung Soh Min
PURPOSE: Anastomotic leakage (AL) after stapled anastomosis in rectal cancer surgery is a major concern. Various types of intraoperative anastomotic air leakage tests (ALTs) have been proposed to reduce AL. This study aimed to evaluate the impact of intraoperative colonoscopy (IOC) as an intraoperative ALT in low anterior resection for rectal cancer. METHODS: A total of 1266 patients were retrospectively reviewed. Among them, 215 patients who underwent IOC as an ALT in rectal cancer surgery were identified...
January 31, 2017: International Journal of Colorectal Disease
https://www.readbyqxmd.com/read/28130593/functional-outcome-following-rectal-surgery-predisposing-factors-for-low-anterior-resection-syndrome
#18
Daniel Ll Hughes, Julie Cornish, Chris Morris
PURPOSE: Developments in surgical techniques and neoadjuvant treatment have enabled an increasing proportion of patients with rectal cancer to undergo sphincter-sparing resections. The avoidance of a permanent stoma can come at the cost of poor bowel function which can significantly impact patients' quality of life. The objective of this study was to identify the incidence and risk factors for the development of bowel dysfunction following rectal cancer surgery. METHODS: Patients undergoing anterior resection for rectal cancer between January 2009 and January 2015 were identified from a rectal cancer database at a single centre...
January 27, 2017: International Journal of Colorectal Disease
https://www.readbyqxmd.com/read/28130592/extended-lymphadenectomy-for-locally-advanced-and-recurrent-rectal-cancer
#19
Panagiotis A Georgiou, S Mohammed Ali, Gina Brown, Shahnawaz Rasheed, Paris P Tekkis
PURPOSE: The purpose of this study is to assess the value of extended (lateral) lymphadenectomy (EL) in the operative management of locally advanced and recurrent rectal cancer. METHODS: Patients that underwent exenterative surgery for locally advanced or recurrent rectal cancer between 2006 and 2009 were included in the study. A decision for EL was taken at the local multidisciplinary meeting based on the radiological findings. Perioperative and oncological outcomes were assessed and compared between the EL and non-EL group prospectively...
January 27, 2017: International Journal of Colorectal Disease
https://www.readbyqxmd.com/read/28130591/comment-on-article-entitled-the-ripasa-score-is-sensitive-and-specific-for-the-diagnosis-of-acute-appendicitis-in-a-western-population
#20
LETTER
Gautam Chandra, Abhinav Shekhar, Rajeev Ranjan Kumar, Sanjay Kumar Yadav
No abstract text is available yet for this article.
January 27, 2017: International Journal of Colorectal Disease
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