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American Journal of Gastroenterology

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https://www.readbyqxmd.com/read/28220782/non-physician-clinicians-in-gi-practice-part-1-current-status-and-utilization
#1
Richard E Moses, Ralph D McKibbin
No abstract text is available yet for this article.
February 21, 2017: American Journal of Gastroenterology
https://www.readbyqxmd.com/read/28220781/therapeutic-drug-monitoring-in-ibd-the-new-standard-of-care-for-anti-tnf-therapy
#2
Konstantinos Papamichael, Adam S Cheifetz
No abstract text is available yet for this article.
February 21, 2017: American Journal of Gastroenterology
https://www.readbyqxmd.com/read/28220780/bacterial-infections-change-natural-history-of-cirrhosis-irrespective-of-liver-disease-severity
#3
Elena Dionigi, Matteo Garcovich, Mauro Borzio, Gioacchino Leandro, Avik Majumdar, Aikaterini Tsami, Vasiliki Arvaniti, Davide Roccarina, Massimo Pinzani, Andrew K Burroughs, James O'Beirne, Emmanuel A Tsochatzis
OBJECTIVES: We assessed the prognostic significance of infections in relation to current prognostic scores and explored if infection could be considered per se a distinct clinical stage in the natural history of cirrhosis. METHODS: We included consecutive patients with cirrhosis admitted to a tertiary referral liver unit for at least 48 h over a 2-year period. Diagnosis of infection was based on positive cultures or strict established criteria. We used competing risk analysis and propensity score matching for data analysis...
February 21, 2017: American Journal of Gastroenterology
https://www.readbyqxmd.com/read/28220779/non-physician-clinicians-in-gi-practice-part-2-utilization-and-risks
#4
Richard E Moses, Ralph D McKibbin
No abstract text is available yet for this article.
February 21, 2017: American Journal of Gastroenterology
https://www.readbyqxmd.com/read/28220778/katie-a-patient-s-perspective
#5
Katie Errico
No abstract text is available yet for this article.
February 21, 2017: American Journal of Gastroenterology
https://www.readbyqxmd.com/read/28220777/medication-management-in-the-pregnant-ibd-patient
#6
Sumona Saha
No abstract text is available yet for this article.
February 21, 2017: American Journal of Gastroenterology
https://www.readbyqxmd.com/read/28220776/katie-the-physician-s-perspective-of-a-young-woman-s-illness-experience
#7
Douglas A Drossman
No abstract text is available yet for this article.
February 21, 2017: American Journal of Gastroenterology
https://www.readbyqxmd.com/read/28195180/successful-resolution-of-recurrent-clostridium-difficile-infection-using-freeze-dried-encapsulated-fecal-microbiota-pragmatic-cohort-study
#8
Christopher Staley, Matthew J Hamilton, Byron P Vaughn, Carolyn T Graiziger, Krista M Newman, Amanda J Kabage, Michael J Sadowsky, Alexander Khoruts
OBJECTIVES: Fecal microbiota transplantation (FMT) is increasingly being used for treatment of recurrent Clostridium difficile infection (R-CDI) that cannot be cured with antibiotics alone. In addition, FMT is being investigated for a variety of indications where restoration or restructuring of the gut microbial community is hypothesized to be beneficial. We sought to develop a stable, freeze-dried encapsulated preparation of standardized fecal microbiota that can be used for FMT with ease and convenience in clinical practice and research...
February 14, 2017: American Journal of Gastroenterology
https://www.readbyqxmd.com/read/28195179/fostering-collaboration-through-creation-of-an-ibd-learning-health-system
#9
Lisa C Johnson, Gil Y Melmed, Eugene C Nelson, Megan M Holthoff, S Alandra Weaver, Tamara S Morgan, Corey A Siegel
No abstract text is available yet for this article.
February 14, 2017: American Journal of Gastroenterology
https://www.readbyqxmd.com/read/28195178/recurrence-of-barrett-s-esophagus-is-rare-following-endoscopic-eradication-therapy-coupled-with-effective-reflux-control
#10
Srinadh Komanduri, Peter J Kahrilas, Kumar Krishnan, Tim McGorisk, Kiran Bidari, David Grande, Laurie Keefer, John Pandolfino
OBJECTIVES: Recent data suggest that effective control of gastroesophageal reflux improves outcomes associated with endoscopic eradication therapy (EET) for Barrett's esophagus (BE). However, the impact of reflux control on preventing recurrent intestinal metaplasia and/or dysplasia is unclear. The aims of the study were: (a) to determine the effectiveness and durability of EET under a structured reflux management protocol and (b) to determine the impact of optimizing anti-reflux therapy on achieving complete eradication of intestinal metaplasia (CE-IM)...
February 14, 2017: American Journal of Gastroenterology
https://www.readbyqxmd.com/read/28195177/prevalence-of-nonalcoholic-steatohepatitis-associated-cirrhosis-in-the-united-states-an-analysis-of-national-health-and-nutrition-examination-survey-data
#11
Mohammad Nasser Kabbany, Praveen Kumar Conjeevaram Selvakumar, Kymberly Watt, Rocio Lopez, Zade Akras, Nizar Zein, William Carey, Naim Alkhouri
OBJECTIVES: Nonalcoholic fatty liver disease (NAFLD) includes a wide spectrum of manifestations ranging from nonalcoholic fatty liver (NAFL) to nonalcoholic steatohepatitis (NASH), fibrosis and eventually cirrhosis. The prevalence of NAFLD has been shown to be increasing over time; however, the prevalence of NASH cirrhosis and advanced fibrosis over time has not been well studied. Estimate the changes in prevalence of NASH cirrhosis and NAFLD-associated advanced fibrosis among adults in the United States...
February 14, 2017: American Journal of Gastroenterology
https://www.readbyqxmd.com/read/28169285/a-randomized-phase-iii-clinical-trial-of-plecanatide-a-uroguanylin-analog-in-patients-with-chronic-idiopathic-constipation
#12
Philip B Miner, William D Koltun, Gregory J Wiener, Marianela De La Portilla, Blas Prieto, Kunwar Shailubhai, Mary Beth Layton, Laura Barrow, Leslie Magnus, Patrick H Griffin
OBJECTIVES: This study assessed the efficacy and safety of plecanatide, a guanylate cyclase-C (GC-C) agonist and the first uroguanylin analog approved for the treatment of chronic idiopathic constipation (CIC). METHODS: This phase III, multicenter, double-blind, placebo-controlled study randomized 1,394 patients with CIC. Patients received either plecanatide (3 or 6 mg) or placebo, orally, once daily, for 12 weeks. The primary efficacy endpoint was the percentage of patients who were durable overall complete spontaneous bowel movement (CSBM) responders over the 12-week treatment period...
February 7, 2017: American Journal of Gastroenterology
https://www.readbyqxmd.com/read/28169284/long-term-glycemic-control-in-adult-patients-undergoing-remote-vs-local-total-pancreatectomy-with-islet-autotransplantation
#13
Samuel J Kesseli, Matthew Wagar, Min K Jung, Kerrington D Smith, Yu Kuei Lin, R Matthew Walsh, Betul Hatipoglu, Martin L Freeman, Timothy L Pruett, Gregory J Beilman, David E R Sutherland, Ty B Dunn, David A Axelrod, Sushela S Chaidarun, Tyler K Stevens, Melena Bellin, Timothy B Gardner
OBJECTIVES: Total pancreatectomy with islet autotransplantation (TPIAT) is increasingly performed with remote islet cell processing and preparation, i.e., with islet cell isolation performed remotely from the primary surgical site at an appropriately equipped islet isolation facility. We aimed to determine whether TPIAT using remote islet isolation results in comparable long-term glycemic outcomes compared with TPIAT performed with standard local isolation. METHODS: We performed a retrospective cohort study of adult patients who underwent TPIAT at three tertiary care centers from 2010 to 2013...
February 7, 2017: American Journal of Gastroenterology
https://www.readbyqxmd.com/read/28139657/another-go-around-for-aspirin-the-gut-is-the-heart-of-the-matter-this-time
#14
Aasma Shaukat
No abstract text is available yet for this article.
January 31, 2017: American Journal of Gastroenterology
https://www.readbyqxmd.com/read/28139656/the-chicago-classification-3-0-results-in-more-normal-findings-and-fewer-hypotensive-findings-with-no-difference-in-other-diagnoses
#15
H Monrroy, D Cisternas, C Bilder, A Ditaranto, J Remes-Troche, A Meixueiro, M A Zavala, J Serra, I Marín, A Ruiz de León, J Pérez de la Serna, A Hani, A Leguizamo, L Abrahao, R Coello, M A Valdovinos
OBJECTIVES: High-resolution manometry (HRM) is the preferred method for the evaluation of motility disorders. Recently, an update of the diagnostic criteria (Chicago 3.0) has been published. The aim of this study was to compare the performance criteria of Chicago version 2.0 (CC2.0) vs. 3.0 (CC3.0) in a cohort of healthy volunteers and symptomatic patients. METHODS: HRM studies of asymptomatic and symptomatic individuals from several centers of Spain and Latin America were analyzed using both CC2...
January 31, 2017: American Journal of Gastroenterology
https://www.readbyqxmd.com/read/28139655/a-multidisciplinary-approach-to-pancreas-cancer-in-2016-a-review
#16
REVIEW
Evan L Fogel, Safi Shahda, Kumar Sandrasegaran, John DeWitt, Jeffrey J Easler, David M Agarwal, Mackenzie Eagleson, Nicholas J Zyromski, Michael G House, Susannah Ellsworth, Ihab El Hajj, Bert H O'Neil, Attila Nakeeb, Stuart Sherman
In this article, we review our multidisciplinary approach for patients with pancreatic cancer. Specifically, we review the epidemiology, diagnosis and staging, biliary drainage techniques, selection of patients for surgery, chemotherapy, radiation therapy, and discuss other palliative interventions. The areas of active research investigation and where our knowledge is limited are emphasized.Am J Gastroenterol advance online publication, 31 January 2017; doi:10.1038/ajg.2016.610.
January 31, 2017: American Journal of Gastroenterology
https://www.readbyqxmd.com/read/28117363/increased-risk-of-gallstone-disease-following-colectomy-for-ulcerative-colitis
#17
Anders Mark-Christensen, Søren Brandsborg, Søren Laurberg, Niels Johansen, Jørn Helmut Pachler, Ole Thorlacius-Ussing, Mie Dilling Kjær, Niels Qvist, Louise Preisler, Jens Hillingsø, Jacob Rosenberg, Peter Jepsen
OBJECTIVES: Biochemical studies suggest that patients who have had a colectomy or restorative proctocolectomy with ileal pouch-anal anastomosis (IPAA) are at an increased risk of developing gallstone disease, but epidemiological studies are lacking. We evaluated the risk of gallstone disease following colectomy and IPAA. METHODS: Individuals who had a colectomy were identified from a national cohort of patients with ulcerative colitis (UC), and controls without colectomy were sampled from within the same cohort, matching on gender, calendar year, and year of birth...
January 24, 2017: American Journal of Gastroenterology
https://www.readbyqxmd.com/read/28117362/a-prospective-study-of-smoking-and-risk-of-synchronous-colorectal-cancers
#18
David A Drew, Reiko Nishihara, Paul Lochhead, Aya Kuchiba, Zhi Rong Qian, Kosuke Mima, Katsuhiko Nosho, Kana Wu, Molin Wang, Edward Giovannucci, Charles S Fuchs, Andrew T Chan, Shuji Ogino
OBJECTIVES: Cigarette smoking has been linked to somatic genetic and epigenetic aberrations, including CpG island methylator phenotype (CIMP)-high, microsatellite instability (MSI)-high and BRAF mutation. These molecular features have been associated with synchronous primary colorectal cancers (CRCs). Thus, we examined the hypothesis that smoking might be associated with the risk of synchronous CRCs. METHODS: Within the Health Professionals Follow-up Study and Nurses' Health Study, we examined the relationship of smoking and incidence of CRC according to tumor synchronicity, using duplication-method Cox proportional hazards regression analysis...
January 24, 2017: American Journal of Gastroenterology
https://www.readbyqxmd.com/read/28117361/the-impact-of-intragastric-balloons-on-obesity-related-co-morbidities-a-systematic-review-and-meta-analysis
#19
REVIEW
Violeta B Popov, Amy Ou, Allison R Schulman, Christopher C Thompson
ObjectivesTherapies less invasive than surgery and more effective than lifestyle and pharmacotherapy are needed to contend with the obesity epidemic. Intragastric balloons (IGBs) are a minimally invasive endoscopic weight loss method recently approved for use in the US. The purpose of the study is to assess the effect of IGBs on metabolic outcomes associated with obesity.MethodsMEDLINE, Embase, and Cochrane Database were searched through July 2016. Dual extraction and quality assessment of studies using Cochrane risk of bias tool were performed independently by two authors...
January 24, 2017: American Journal of Gastroenterology
https://www.readbyqxmd.com/read/28117360/barrett-s-esophagus-with-low-grade-dysplasia-ablate-or-wait
#20
Sravanthi Parasa, Prateek Sharma
No abstract text is available yet for this article.
January 24, 2017: American Journal of Gastroenterology
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