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American Journal of Gastroenterology

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https://www.readbyqxmd.com/read/29925917/it-s-actually-a-little-complicated-antibiotics-for-uncomplicated-diverticulitis
#1
EDITORIAL
Anne F Peery
The assumption that acute uncomplicated diverticulitis requires antibiotics has been challenged. In this issue, the Dutch Diverticular Disease Collaborative Study Group report the 2-year follow-up to their trial of observation vs. treatment with amoxicillin-clavulanic acid for acute uncomplicated diverticulitis. The new study provides useful insights on the natural history of acute uncomplicated diverticulitis. The most intriguing data compared rates of elective sigmoid resection between the groups. There was a trend toward more elective surgery in the observation group compared to those in the antibiotic group...
June 21, 2018: American Journal of Gastroenterology
https://www.readbyqxmd.com/read/29925916/needleless-transcutaneous-electrical-acustimulation-a-pilot-study-evaluating-improvement-in-post-operative-recovery
#2
Bo Zhang, Feng Xu, Pingping Hu, Mingyuan Zhang, Kehui Tong, Gang Ma, Yuemei Xu, Liang Zhu, Jiande D Z Chen
BACKGROUND: Functional gastrointestinal disturbance occurs after abdominal surgeries and could last for an extended period of time in some cases. This study was designed (1) to evaluate the effects of needleless transcutaneous electrical acustimulation (TEA) on postoperative recovery, and (2) to investigate the mechanisms involving autonomic function in postoperative patients after removal of gastrointestinal cancers. METHODS: Forty-two patients (33 male, age: 69...
June 21, 2018: American Journal of Gastroenterology
https://www.readbyqxmd.com/read/29925915/a-randomized-controlled-trial-of-opt-in-versus-opt-out-colorectal-cancer-screening-outreach
#3
Shivan J Mehta, Tanya Khan, Carmen Guerra, Catherine Reitz, Timothy McAuliffe, Kevin G Volpp, David A Asch, Chyke A Doubeni
OBJECTIVES: Colorectal cancer (CRC) screening uptake is suboptimal, despite national efforts to increase screening rates. Behavioral economic approaches such as changing defaults may increase participation. We compare response rates to opt-in or opt-out messaging in mailed fecal immunochemical test (FIT) outreach. METHODS: This is a two-arm randomized controlled trial among 314 patients aged 50-74 years who had at least two primary care visits in the 2-year pre-enrollment period and were screening-eligible but not up-to-date...
June 21, 2018: American Journal of Gastroenterology
https://www.readbyqxmd.com/read/29925914/overtube-assisted-eus-guided-access-of-the-common-bile-duct-in-a-patient-with-roux-en-y-gastric-bypass-anatomy
#4
Juliana Yang, Payal Saxena, Lea Fayad, Omid Sanaei, Robert Moran, Olaya Brewer-Gutierrez, Christopher Paiji, Mouen A Khashab
No abstract text is available yet for this article.
June 21, 2018: American Journal of Gastroenterology
https://www.readbyqxmd.com/read/29925913/no-benefit-of-concomitant-5-aminosalicylates-in-patients-with-ulcerative-colitis-escalated-to-biologic-therapy-pooled-analysis-of-individual-participant-data-from-clinical-trials
#5
Siddharth Singh, James A Proudfoot, Parambir S Dulai, Vipul Jairath, Mathurin Fumery, Ronghui Xu, Brian G Feagan, William J Sandborn
OBJECTIVES: 5-aminosalicylates (5-ASA) are frequently continued in patients with moderate-severe ulcerative colitis (UC), even after escalation to biologic agents, without evaluation of the benefit of this approach. We conducted an individual participant data (IPD) pooled analysis of trials of infliximab and golimumab in UC, to evaluate whether concomitant use of 5-ASA modifies clinical outcomes among anti-tumor necrosis factor (TNF)-α-treated patients. METHODS: We included IPD from five trials of infliximab and golimumab in patients with moderate-severe UC (ACT-1 and -2, PURSUIT-SC, PURSUIT-M, NCT00336492)...
June 21, 2018: American Journal of Gastroenterology
https://www.readbyqxmd.com/read/29925912/persistence-with-immunomodulator-monotherapy-use-and-incidence-of-therapeutic-ineffectiveness-among-users-of-immunomodulator-monotherapy-in-ibd
#6
Laura E Targownik, Stella Leung, Lisa M Lix, Harminder Singh, Charles N Bernstein
OBJECTIVES: Immunomodulator (IM)-based monotherapy with thiopurines or methotrexate is being increasingly supplanted in the management of moderate-to-severe IBD by more efficacious biologic agents. However, given their low cost, IMs may still have a selective role in this setting. METHODS: We used a Canadian population-based dataset of persons with IBD spanning from 1996 until 2014 to assess the initiation and continued use of IM monotherapy, the incidence of outcomes associated with ineffectiveness (defined as IBD-related hospitalization, IBD-resective surgery, systemic corticosteroid (CS) use, or the need for biologic therapy), and the demographic and disease-related characteristics associated with persistence on IM monotherapy and IBD-associated adverse outcomes...
June 21, 2018: American Journal of Gastroenterology
https://www.readbyqxmd.com/read/29925911/acute-rejection-of-a-duodenal-graft
#7
Olivier de Rougemont, Christian E Oberkofler, Tim Reese, Christoph Gubler
No abstract text is available yet for this article.
June 21, 2018: American Journal of Gastroenterology
https://www.readbyqxmd.com/read/29925910/successful-daa-based-treatment-of-hcv-related-fibrosing-cholestatic-hepatitis-after-liver-transplantation-due-to-a-fulminant-liver-failure
#8
LETTER
Marcin Krawczyk, Bartłomiej Gawęda, Artur Kośnik, Sławomir Rejowski, Piotr Remiszewski, Marek Krawczyk, Piotr Milkiewicz, Joanna Raszeja-Wyszomirska
No abstract text is available yet for this article.
June 21, 2018: American Journal of Gastroenterology
https://www.readbyqxmd.com/read/29921898/response-to-yeomans-et-al
#9
LETTER
Shih-Wei Lai, Cheng-Li Lin, Shih-Chang Hung
No abstract text is available yet for this article.
June 20, 2018: American Journal of Gastroenterology
https://www.readbyqxmd.com/read/29915405/wheat-intolerance-and-chronic-gastrointestinal-symptoms-in-an-australian-population-based-study-association-between-wheat-sensitivity-celiac-disease-and-functional-gastrointestinal-disorders
#10
Michael D E Potter, Marjorie M Walker, Michael P Jones, Natasha A Koloski, Simon Keely, Nicholas J Talley
OBJECTIVES: Wheat avoidance in the absence of celiac disease (CD) is common but occurrence of concurrent functional gastrointestinal disorders (FGIDs) in this group is uncertain. The aims of this study were to determine the prevalence of self-reported wheat or gluten sensitivity and doctor diagnosed CD in an Australian population, define the associated gastrointestinal (GI) symptoms and FGIDs, and determine the relationship between self-reported wheat sensitivity, demographic and medical factors...
June 19, 2018: American Journal of Gastroenterology
https://www.readbyqxmd.com/read/29915404/the-global-phenomenon-of-self-reported-wheat-sensitivity
#11
EDITORIAL
Imran Aziz
Celiac disease affects about 1% of the population and is treated with a gluten-free diet. However, the last decade has seen a huge rise in individuals self-reporting wheat sensitivity, and consuming a gluten-free diet, despite not having a doctor-diagnosis of celiac disease. A recent flurry of observational studies from across the globe suggests that approximately 10% of the population is self-reporting wheat sensitivity. They describe a constellation of intestinal and extra-intestinal symptoms attributed to ingestion of gluten-based products...
June 19, 2018: American Journal of Gastroenterology
https://www.readbyqxmd.com/read/29915403/h-pylori-and-barrett-s-esophagus-implications-for-populations-and-practice
#12
EDITORIAL
Colin W Howden
In this edition of the American Journal of Gastroenterology, Wang and colleagues report the results of an analysis of six different case-control studies examining the relationship between Helicobacter pylori (H. pylori) infection and Barrett's esophagus. They present a cogent argument that there is an inverse association between these two that is mediated via GERD. This is broadly consistent with previous reports. While further establishing this inverse association, the findings should not materially influence our routine clinical practice regarding GERD or H...
June 19, 2018: American Journal of Gastroenterology
https://www.readbyqxmd.com/read/29915402/endoscopic-removal-of-a-fish-bone-migrating-and-penetrating-the-stomach
#13
Sho Sasaki, Jun Nishikawa, Mitsuru Saito, Shigeyuki Suenaga, Toshiyuki Uekitani, Yuichiro Yokoyama, Isao Sakaida
No abstract text is available yet for this article.
June 19, 2018: American Journal of Gastroenterology
https://www.readbyqxmd.com/read/29915401/invagination-as-manifestation-of-a-perivascular-epithelioid-cell-neoplasm-pecoma-of-the-colon
#14
Lukas Neuhaus, Andreas Probst, Helmut Messmann, Lena Siebert, Dmytro Vlasenko, Abbas Agaimy, Saskia Ting
No abstract text is available yet for this article.
June 19, 2018: American Journal of Gastroenterology
https://www.readbyqxmd.com/read/29915400/office-based-point-of-care-testing-iga-igg-deamidated-gliadin-peptide-for-celiac-disease
#15
Michelle S Lau, Peter D Mooney, William L White, Michael A Rees, Simon H Wong, Marios Hadjivassiliou, Peter H R Green, Benjamin Lebwohl, David S Sanders
OBJECTIVES: Celiac disease (CD) is common yet under-detected. A point of care test (POCT) may improve CD detection. We aimed to assess the diagnostic performance of an IgA/IgG-deamidated gliadin peptide (DGP)-based POCT for CD detection, patient acceptability, and inter-observer variability of the POCT results. METHODS: From 2013-2017, we prospectively recruited patients referred to secondary care with gastrointestinal symptoms, anemia and/or weight loss (group 1); and patients with self-reported gluten sensitivity with unknown CD status (group 2)...
June 19, 2018: American Journal of Gastroenterology
https://www.readbyqxmd.com/read/29915399/anatomical-and-functional-features-of-the-internal-rectal-prolapse-with-outlet-obstruction-determined-with-3d-endorectal-ultrasonography-and-high-resolution-anorectal-manometry-an-observational-case-control-study
#16
Luigi Brusciano, Salvatore Tolone, Paolo Limongelli, Gianmattia Del Genio, Federico Messina, Jacopo Martellucci, Mariachiara Lanza Volpe, Antonio Longo, Ludovico Docimo
OBJECTIVES: To investigate correlation between rectal wall thickness (RWT) and anorectal pressures, in obstructed defecation syndrome (ODS) patients caused by internal rectal prolapse. METHODS: ODS patients and healthy volunteers (HVs) underwent 3D endorectal ultrasound (3D-EUS) and high-resolution anorectal manometry (HRAM); RWT, total rectal wall volume (TRWV), pushing endorectal pressure (PEP), recto-anal gradient were determined RESULTS: We enrolled 35 ODS patients and 25 HVs...
June 19, 2018: American Journal of Gastroenterology
https://www.readbyqxmd.com/read/29915398/response-to-golfeyz
#17
LETTER
Benjamin Lebwohl, Jonas F Ludvigsson
No abstract text is available yet for this article.
June 19, 2018: American Journal of Gastroenterology
https://www.readbyqxmd.com/read/29915397/response-to-perrella-et-al
#18
LETTER
Paul Y Kwo, Mitchell L Shiffman, David E Bernstein
No abstract text is available yet for this article.
June 19, 2018: American Journal of Gastroenterology
https://www.readbyqxmd.com/read/29915396/probiotics-in-gastroenterology-how-pro-is-the-evidence-in-adults
#19
REVIEW
Ronald L Koretz
Probiotic usage has become popular with both medical practitioners and the community in general; patients commonly seek advice regarding what, if any, such preparation would be useful for their own diseases. Since such advice should be evidence-based, identified randomized clinical trials (RCTs) for a number of gastrointestinal conditions were reviewed; the data were organized by individual probiotic genera/species. Only trials in adults were considered. Most of the identified RCTs were small and low-quality, so any conclusions to be drawn will be limited at least by methodologic problems...
June 19, 2018: American Journal of Gastroenterology
https://www.readbyqxmd.com/read/29915395/treatment-of-endoscopy-associated-cerebral-gas-embolism
#20
Jeffr Cooper
No abstract text is available yet for this article.
June 19, 2018: American Journal of Gastroenterology
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