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Urology

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https://www.readbyqxmd.com/read/28923410/extended-case-duration-and-hypotension-are-associated-with-higher-grade-postoperative-complications-after-urinary-diversion-for-non-oncological-disease
#1
Y Santiago-Lastra, Michael R Mathis, Elizabeth Andraska, Aleda L Thompson, Bahaa S Malaeb, Anne P Cameron, J Quentin Clemens, John T Stoffel
OBJECTIVE: To report survival for patients who undergo urinary diversion for benign indications and to identify risk factors for morbidity at 90 days. METHODS: This is a retrospective review of consecutive urinary diversions with or without cystectomy for non-oncological indications at a single institution. The indication for diversion was intractable incontinence, upper tract deterioration, urinary fistula, and unmanageable bladder pain. Patients were categorized according to their most severe complication within 90 days of surgery, using the Clavien-Dindo system...
September 15, 2017: Urology
https://www.readbyqxmd.com/read/28917606/argus-t-sling-in-182-male-patients-short-term-results-of-a-multicenter-study
#2
Salvatore Siracusano, Francesco Visalli, Michele Favro, Carlo Tallarigo, Mauro Saccomanni, Alexander Kugler, Alberto Diminutto, Renato Talamini, Walter Artibani
OBJECTIVES: To evaluate the short-term results with Argus-T sling in patients affected by post-prostatectomy incontinence (PPI) METHODS: 182 patients affected by PPI were treated with Argus-T sling at 5 Urological centers from June 2008 to March 2013. The preoperative evaluation included medical history, pad count (1-2 pads: mild PPI; 3-5 pads: moderate PPI; >5 pads: severe PPI), VAS on continence, QoL score scale, physical examination, cystoscopy and urodynamic evaluation. Postoperative evaluation was performed six weeks postoperatively, and late follow-up (FU) was achieved in April 2013...
September 13, 2017: Urology
https://www.readbyqxmd.com/read/28916254/development-of-a-natural-language-processing-engine-to-generate-bladder-cancer-pathology-data-for-health-services-research
#3
Florian R Schroeck, Olga V Patterson, Patrick R Alba, Erik A Pattison, John D Seigne, Scott L DuVall, Douglas J Robertson, Brenda Sirovich, Philip P Goodney
OBJECTIVE: To take a first step towards assembling population based cohorts of bladder cancer patients with longitudinal pathology data, we developed and validated a natural language processing (NLP) engine that abstracts pathology data from full text pathology reports. METHODS: Using 600 bladder pathology reports randomly selected from the Department of Veterans Affairs, we developed and validated an NLP engine to abstract data on histology, invasion (presence versus absence and depth), grade, presence of muscularis propria, and presence of carcinoma in situ...
September 12, 2017: Urology
https://www.readbyqxmd.com/read/28916253/the-place-of-transanal-endoscopic-surgery-in-the-treatment-of-recto-urethral-fistula
#4
X Serra-Aracil, M Labro-Ciurans, L Mora-Lopez, J Muñoz-Rodriguez, R Martos-Calvo, J Prats-López, S Navarro-Soto
OBJECTIVES: To assess the role of TEO/TEM in recto-urethral fistulas (RUF). RUF may appear after radical prostatectomy. Their treatment represents a challenge; many therapies have been proposed, from conservative to aggressive surgical approaches. Transanal endoscopic surgery (TEO/TEM) is a minimally invasive technique to access the site of the RUF to perform repair. METHODS: Observational study with prospective data collection, conducted between September 2006 and December 2015...
September 12, 2017: Urology
https://www.readbyqxmd.com/read/28916252/decreased-monoamine-oxidase-a-expression-and-activity-in-the-bladders-of-rats-with-partial-outlet-obstruction
#5
Mai Michishita, Kazuo Yano, Ken-Ichi Tomita, Satoru Yoshikawa, Osamu Matsuzaki, Ken-Ichi Kasahara
OBJECTIVE To investigate changes in expression and activity of monoamine oxidase A (MAO-A) in rats with partial bladder outlet obstruction (pBOO). Previous studies suggested that monoamines, such as serotonin (5-hydroxytryptamine; 5-HT) and noradrenaline (NA), are involved in bladder hyperactivity secondary to pBOO. However, little is known about the role of MAO-A, an enzyme oxidizing 5-HT and NA, in the pathogenesis. METHODS Female Sprague Dawley rats were subjected to sham or pBOO operations for 7 days, then their bladders were isolated...
September 12, 2017: Urology
https://www.readbyqxmd.com/read/28893633/enhanced-recovery-open-versus-laparoscopic-left-donor-nephrectomy-a-randomized-controlled-trial
#6
Ahmed M Mansour, Ahmed R El-Nahas, Bedeir Ali-El-Dein, Ahmed Abdelfattah, Ahmed Hamed, Ahmed Abdel-Rahman, Ibrahim Eraky, Ahmed A Shokeir
OBJECTIVE: To compare recovery outcomes between laparoscopic donor nephrectomy (LDN) and open donor nephrectomy (ODN) within a specified Enhanced Recovery Program (ERP) for left kidney donations. MATERIALS AND METHODS: A phase III randomized trial was conducted between January 2013 and June 2015, eligible left side donors were randomized to laparoscopic or open donor nephrectomy in a 1:1 ratio with recovery optimized within a standardized ERP. The primary outcome was patient-reported measure of physical fatigue, as measured by the physical fatigue domain of the translated Multidimensional Fatigue Inventory 20 (MFI-20)...
September 8, 2017: Urology
https://www.readbyqxmd.com/read/28893632/patients-experiences-with-extramammary-paget-s-disease-an-online-pilot-study-querying-a-patient-support-group
#7
Paul H Chung, Jeremy T Kampp, Bryan B Voelzke
OBJECTIVE: To illustrate the heterogeneous care delivered to patients with Extramammary Paget's Disease (EMPD), a rare and lethal malignancy with poorly described treatment methodologies, by characterizing the clinical and pathological characteristics of an international patient support group. METHODS: Institutional review board approval was obtained to develop and distribute a non-validated survey to patients from an international, online EMPD support group. The survey was developed to capture patient clinical and pathological details and was distributed between January 2017 and February 2017...
September 8, 2017: Urology
https://www.readbyqxmd.com/read/28893631/a-75-year-old-african-american-female-with-an-incidentally-identified-renal-mass-after-traumatic-fall
#8
Zachary S Feuer, Noam D Fine, Jyoti D Chouhan, Daniel A Segal, Michael Tyler, Steve Xie, Patrick J Hammill, Llewellyn M Hyacinthe, Brian K McNeil, Andrew G Winer
No abstract text is available yet for this article.
September 8, 2017: Urology
https://www.readbyqxmd.com/read/28890152/letter-to-the-editor-re-leapman-et%C3%A2-al-up-and-away-five-decades-of-urologic-investigation-in-microgravity
#9
LETTER
Helena C Chang, Mathew Sorensen, Jonathan D Harper, Michael R Bailey, Dorit Donoviel
No abstract text is available yet for this article.
September 7, 2017: Urology
https://www.readbyqxmd.com/read/28890151/when-to-perform-preoperative-bone-scintigraphy-for-kidney-cancer-staging-indications-for-preoperative-bone-scintigraphy
#10
Alessandro Larcher, Fabio Muttin, Nicola Fossati, Paolo Dell'Oglio, Ettore Di Trapani, Armando Stabile, Francesco Ripa, Francesco Trevisani, Cristina Carenzi, Maria Picchio, Alberto Briganti, Andrea Salonia, Alexandre Mottrie, Roberto Bertini, Francesco Montorsi, Umberto Capitanio
OBJECTIVES: To identify an objective and reproducible strategy for preoperative staging bone scintigraphy [BS] in patients diagnosed with renal cell carcinoma [RCC], since in absence of objective criteria, the decision to perform preoperative BS remains a subjective practice. METHODS: 2,008 RCC patients treated with surgery and prospectively included into an institutional database. The study outcome was presence of one or more bone lesions suspicious for metastases at staging BS...
September 7, 2017: Urology
https://www.readbyqxmd.com/read/28888753/the-role-of-gut-microbiome-in-the-pathogenesis-of-prostate-cancer-a-prospective-pilot-study
#11
David M Golombos, Abimbola Ayangbesan, Padraic O'Malley, Patrick Lewicki, LaMont Barlow, Christopher E Barbieri, Chrystal Chan, Casey DuLong, Galeb Abu-Ali, Curtis Huttenhower, Douglas S Scherr
OBJECTIVE: To elucidate potential biomarkers or mechanistic principles involved with the gut microbiota and its impact on prostate cancer pathogenesis. MATERIALS AND METHODS: A prospective case-control pilot study evaluating the gut microbiome of 20 men with either benign prostatic conditions (n = 8) or intermediate/high risk clinically localized prostate cancer (Gleason ≥4+3 cN0M0) (n = 12) undergoing care at tertiary referral center from 9/1/2015 - 3/1/2016...
September 6, 2017: Urology
https://www.readbyqxmd.com/read/28888752/incidence-of-clinically-significant-prostate-cancer-after-a-diagnosis-of-atypical-small-acinar-proliferation-asap-high-grade-prostatic-intraepithelial-neoplasia-hgpin-or-benign-tissue
#12
Scott Wiener, Peter Haddock, Joe Cusano, Ilene Staff, Tara McLaughlin, Joseph Wagner
Objective To assess the incidence of clinically significant and insignificant prostate cancer after an initial biopsy that revealed either atypical small acinar proliferation (ASAP), high grade prostatic intraepithelial neoplasia (HGPIN), or benign tissue. Methods We retrospectively identified patients diagnosed with ASAP, HGPIN or benign tissue who had a repeat prostate biopsy within one year of diagnosis during 1987-2015. We compared the incidence of any prostate cancer and clinically significant prostate cancer (based on Gleason score, prostate-specific antigen (PSA), number of positive cores and core volume) for each diagnostic group...
September 6, 2017: Urology
https://www.readbyqxmd.com/read/28888751/female-outlet-obstruction-after-anti-incontinence-surgery
#13
REVIEW
Henry Tran, Matthew Rutman
Numerous surgical options are available for management of stress urinary incontinence in women, including urethral bulking agents, pubo-vaginal slings, retropubic bladder neck suspensions, mid-urethral slings, and even artificial urinary sphincters. We discuss the incidence, etiology, diagnosis, evaluation, and management of bladder outlet obstruction (BOO) after anti-incontinence surgery in females. This problem presents with a wide range of symptoms. Urodynamic evaluation is not always diagnostic, but can be helpful...
September 6, 2017: Urology
https://www.readbyqxmd.com/read/28888750/primary-mediastinal-pure-seminomatous-germ-cell-tumor-germinoma-as-a-rare-cause-of-precocious-puberty-in-a-9-year-old-patient
#14
Alejandra Bravo-Balado, Lynda Torres Castellanos, Adriana Carrillo Rodríguez, Daniel Gómez Zapata, Juan Javier Lammoglia Hoyos, Rafael Andrade, Jaime Pérez Niño
Less than 5-7% of germ cell tumors (GCTs) are extragonadal, being the central nervous system (CNS) the most common location in children, followed by retroperitoneum and mediastinum. Only 10% of mediastinal tumors are malignant and one third of these are pure seminomas (germinomas). We report the case of a 9 year-old boy with development of secondary sexual characteristics. Beta human chorionic gonadotropin (B-hCG) was elevated and a mediastinal mass was found. Final histology showed a pure seminomatous germ cell tumor (SGCT)...
September 6, 2017: Urology
https://www.readbyqxmd.com/read/28888749/complete-penile-disassembly-for-repair-of-epispadias-causes-erectile-tissue-alteration-through-tgf-%C3%AE-1-overexpression-in-rabbit-model
#15
Ali Tourchi, Mahsa Shabaninia, Meghan Stewart, Hiroshi Miyamoto, Heather Di Carlo, John Gearhart
OBJECTIVE: To investigate corporal tissue viability and changes in endothelial content following current techniques used for epispadias repair in animal model MATERIALS AND METHODS: Sixty rabbits were allocated into three groups: Sham operation (penile degloving), complete disassembly model, and Cantwell-Ransley model. On weeks 2, 4, 12, and 24 post-op, the penile tissue was harvested and processed for (i)Masson's trichrome staining for smooth muscle cell(SMC)/collagen ratios (ii)immunohistochemical staining for endothelial factor(CD31) and TGF-β1 (iii)TUNEL assay to detect apoptosis...
September 6, 2017: Urology
https://www.readbyqxmd.com/read/28886994/successful-treatment-of-residual-curvature-in-peyronie-s-disease-in-men-previously-treated-with-intralesional-collagenase-clostridium-histolyticum
#16
Kenneth DeLay, Linley Diao, Hoang M T Nguyen, Jonathan Zurawin, Russell Libby, Faysal Yafi, Wayne J G Hellstrom
OBJECTIVE: To determine the success and feasibility of surgically correcting residual curvature after intralesional collagenase Clostridium histolyticum (CCH) for the treatment of Peyronie's disease. METHODS: We performed a retrospective analysis of patients who had intralesional CCH treatment for (PD) and who subsequently underwent penile plication (PP), plaque incision and grafting (PIG), or inflatable penile prosthesis (IPP) placement. RESULTS: Ten men who underwent PP, PIG, or IPP for the treatment of residual curvature after intralesional CCH were identified...
September 5, 2017: Urology
https://www.readbyqxmd.com/read/28882782/prostate-cancer-in-transgender-women-incidence-etiopathogenesis-and-management-challenges
#17
Nicholas A Deebel, Jacqueline P Morin, Riccardo Autorino, Randy Vince, Baruch Grob, Lance J Hampton
OBJECTIVES: To critically analyze the available evidence regarding the incidence, etiopathogenesis, and management of CaP in this specific subset of patients. In addition, this manuscript aims to present a recent case report of a transgender woman with a unique presentation at the author's institution. METHODS: An electronic non-systematic literature search was performed to identify pertinent studies. PubMed search engine was queried by using the following search terms: "prostate cancer", "male to female transsexual", "transgender patient", "androgen+prostate cancer", "estrogen therapy+prostate cancer", "health care barrier"...
September 4, 2017: Urology
https://www.readbyqxmd.com/read/28882781/ureteroscopic-urinary-stone-treatment-among-patients-with-renal-anomalies-patient-characteristics-and-treatment-outcomes
#18
Jaap D Legemate, Barbaros Baseskioglu, Jakub Dobruch, Jorge Gutierrez-Aceves, Oscar Negrete, Carlos Rioja Sanz, Muharrem Murat Yildiz, Jean Jmch de la Rosette
OBJECTIVES: To evaluate patients' characteristics, surgical procedure data, and outcomes of URS stone treatment in patients with a horseshoe kidney (HSK), ectopic kidney (EK), and malrotated kidney (MK). METHODS: This study is a sub-analysis of the CROES URS Global Study, which was a prospective multicenter observational study, collecting data on URS stone treatment from consecutive patients over a 1-year period. 114 Centers participated in 32 countries. This analysis acuminated on URS stone treatment in the specified renal anomalies: HSK, EK and MK...
September 4, 2017: Urology
https://www.readbyqxmd.com/read/28882780/author-reply-re-leapman-et%C3%A2-al-up-and-away-five-decades-of-urologic-investigation-in-microgravity-urology-2017-106-18-25
#19
LETTER
Michael S Leapman, Jeffrey A Jones
No abstract text is available yet for this article.
September 4, 2017: Urology
https://www.readbyqxmd.com/read/28882779/safety-and-effectiveness-of-holmium-laser-enucleation-of-the-prostate-using-a-low-power-laser
#20
Shingo Minagawa, Shinsuke Okada, Hirofumi Morikawa
OBJECTIVE: To assess the safety and effectiveness of holmium laser enucleation of the prostate (HoLEP) using a low-power 30 W holmium laser with an en-bloc enucleation technique. METHODS: We retrospectively analyzed 74 patients with a diagnosis of benign prostatic hyperplasia treated with HoLEP using a 30 W laser set at 1.5 J with a frequency of 20 Hz, as a low-power setting. The enucleation process was performed using the en-bloc technique. Forty-four patients were operated on by an experienced surgeon, while 30 patients were operated on by 2 less experienced surgeons...
September 4, 2017: Urology
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