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Tropical Medicine & International Health: TM & IH

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https://www.readbyqxmd.com/read/28544500/non-communicable-diseases-and-hiv-care-and-treatment-models-of-integrated-service-delivery
#1
REVIEW
Malia Duffy, Bisola Ojikutu, Soa Andrian, Elaine Sohng, Thomas Minior, Lisa R Hirschhorn
OBJECTIVES: Non-communicable diseases (NCD) are a growing cause of morbidity in low-income countries including in people living with Human Immunodeficiency Virus (HIV). Integration of NCD and HIV services can build upon experience with chronic care models from HIV programs. We describe models of NCD and HIV integration, challenges, and lessons learned. METHODS: Literature review of articles on integrated NCD and HIV programs in low-income countries and key informant interviews with leaders of identified integrated NCD and HIV programs...
May 24, 2017: Tropical Medicine & International Health: TM & IH
https://www.readbyqxmd.com/read/28544285/salmonella-typhi-genomics-envisaging-the-future-of-typhoid-eradication
#2
REVIEW
Kien-Pong Yap, Kwai Lin Thong
Next-generation whole genome sequencing has revolutionized the study of infectious diseases in recent years. The availability of genome sequences and its understanding have transformed the field of molecular microbiology, epidemiology, infection treatments and vaccine developments. We review the key findings of the publicly accessible genomes of Salmonella enterica serovar Typhi since the first complete genome to the most recent release of thousands of S. typhi genomes, which remarkably shape the genomic research of S...
May 24, 2017: Tropical Medicine & International Health: TM & IH
https://www.readbyqxmd.com/read/28544728/index-case-finding-facilitates-identification-and-linkage-to-care-of-children-and-young-adults-living-with-hiv-aids-in-malawi
#3
Saeed Ahmed, Rachael A Sabelli, Katie Simon, Nora E Rosenberg, Elijah Kavuta, Mwelura Harawa, Spencer Dick, Frank Linzie, Peter N Kazembe, Maria H Kim
OBJECTIVES: Evaluation of a novel index case-finding and linkage-to-care program to identify and link HIV-infected children (1-15 years) and young adults (>15-24 years) to care. METHODS: HIV-infected patients enrolled in HIV services were screened and those who reported untested household members (index cases) were offered home or facility-based HIV testing and counseling (HTC) of their household by a community health worker (CHW). HIV-infected household members identified were enrolled in a follow-up program offering home and facility-based follow-up by CHWs...
May 23, 2017: Tropical Medicine & International Health: TM & IH
https://www.readbyqxmd.com/read/28544099/genetic-signatures-coupled-with-lineage-shift-characterize-endemic-evolution-of-dengue-virus-serotype-2-during-2015-outbreak-in-delhi-india
#4
Manish Chandra Choudhary, Ekta Gupta, Shvetank Sharma, Nadeem Hasnain, Pragya Agarwala
OBJECTIVE: In 2015 New Delhi witnessed a massive outbreak of Dengue virus (DENV) resulting in high morbidity and mortality. We report the molecular characterization of the dominant circulating DENV strain to understand its evolution and dispersal. MATERIALS AND METHODS: DENV infections were diagnosed by detection of IgM/NS1 antigen and serotyping was performed by C-PrM PCR. Envelope gene was amplified and variation(s) in envelope gene were analyzed. Phylogenetic tree construction, time-based phylogeny and origin of DENV were analyzed...
May 23, 2017: Tropical Medicine & International Health: TM & IH
https://www.readbyqxmd.com/read/28544032/prevalence-of-diabetes-mellitus-in-chinese-children-with-thalassaemia-major
#5
Yuzhen Liang, Rekha Bajoria, Yan Jiang, Hongwei Su, Hongfei Pan, Ning Xia, Ratna Chatterjee, Yongrong Lai
OBJECTIVE: Diabetes mellitus is a common endocrinopathy in patients with β-thalassaemia major (β-TM), which is high prevalent in southern China. This study aimed to determine the cause and prevalence of glycaemic disorders in Chinese children with β-TM. METHODS: In this prospective study, fasting glucose and insulin (FINS) levels were assessed in 267 β-TM and 80 non-TM control children. Homeostatic model assessment (HOMA) and the quantitative insulin sensitivity check index (QUICKI) were evaluated...
May 22, 2017: Tropical Medicine & International Health: TM & IH
https://www.readbyqxmd.com/read/28544070/the-importance-of-assessing-out-of-pocket-payments-when-the-financing-of-antiretroviral-therapy-is-transitioned-to-domestic-funding-findings-from-vietnam
#6
Benjamin Johns, Le Bao Chau, Kieu Huu Hanh, Nguyen Thuy Huong, Hoa Mai Do, Anh Thuy Duong, Long Hoang Nguyen
OBJECTIVE: To assess out-of-pocket payments and catastrophic health expenditures among antiretroviral therapy (ART) patients in Vietnam, and to model catastrophic payments under different copayment scenarios when the primary financing of ART changes to social health insurance. METHODS: Cross-sectional facility-based survey of 843 patients at 42 health facilities representative of 87% of ART patients in 2015. RESULTS: Because of donor and government funding, no payments were made for antiretroviral drugs...
May 19, 2017: Tropical Medicine & International Health: TM & IH
https://www.readbyqxmd.com/read/28510998/new-onset-type-2-diabetes-mellitus-among-patients-receiving-hiv-care-at-newlands-clinic-harare-zimbabwe-retrospective-cohort-analysis
#7
Cleophas Chimbetete, Catrina Mugglin, Tinei Shamu, Bindu Kalesan, Barbara Bertisch, Matthias Egger, Olivia Keiser
OBJECTIVE: To assess the incidence and associated factors of Type 2 Diabetes Mellitus (T2DM) among people living with HIV (PLHIV) in Zimbabwe. METHODS: We analyzed data of all HIV-infected patients older than 16 years who attended Newlands Clinic between March 1, 2004 and April 29, 2015. The clinic considers patients whose random blood sugar is higher than 11.1 mmol/L and which is confirmed by a fasting blood sugar higher than 7.0 mmol/L to have T2DM. T2DM is also diagnosed in symptomatic patients who have a RBS >11...
May 16, 2017: Tropical Medicine & International Health: TM & IH
https://www.readbyqxmd.com/read/28510997/impact-of-m-health-application-used-by-community-health-volunteers-on-improving-utilization-of-maternal-newborn-and-child-health-care-services-in-a-rural-area-of-uttar-pradesh-india
#8
Shankar Prinja, Ruby Nimesh, Aditi Gupta, Pankaj Bahuguna, Madhu Gupta, Jarnail Singh Thakur
OBJECTIVE: To raise the quality of counselling by community health volunteers resulting in improved uptake of maternal, neonatal and child health services (MNCH), an m-health application was introduced under a project named 'Reducing Maternal and Newborn Deaths (ReMiND)' in district Kaushambi in India. We report the impact of this project on coverage of key MNCH services. METHODS: A pre and post quasi-experimental design was undertaken to assess the impact of intervention...
May 16, 2017: Tropical Medicine & International Health: TM & IH
https://www.readbyqxmd.com/read/28510994/improved-detection-of-burkholderia-pseudomallei-from-non-blood-clinical-specimens-using-enrichment-culture-and-pcr-narrowing-diagnostic-gap-in-resource-constrained-settings
#9
Chaitanya Tellapragada, Tushar Shaw, Annet D'Souza, Vandana Kalwaje Eshwara, Chiranjay Mukhopadhyay
OBJECTIVES: To evaluate the diagnostic utility of enrichment culture and PCR for improved case detection rates of non-bacteremic form of melioidosis in limited resource settings. METHODS: Clinical specimens (n=525) obtained from patients presenting at a tertiary care hospital of south India with clinical symptoms suggestive of community-acquired pneumonia, lower respiratory tract infections, superficial or internal abscesses, chronic skin ulcers and bone or joint infections were tested for the presence of Burkholderia pseudomallei using conventional culture (CC), enrichment culture (EC) and PCR...
May 16, 2017: Tropical Medicine & International Health: TM & IH
https://www.readbyqxmd.com/read/28510990/perioperative-nutrition-management-as-an-important-component-of-surgical-capacity-in-low-and-middle-income-countries
#10
REVIEW
Shinji Nakahara, Do Huy Nguyen, An Tho Bui, Michiko Sugiyama, Masao Ichikawa, Tetsuya Sakamoto, Teiji Nakamura
Needs for surgical care are growing in low- and middle-income countries. Existing surgical care capacity indicators, focusing on the availability of equipment, personnel, and operation and anaesthetic skills, are not intended to evaluate perioperative nutrition management, which influences surgical outcomes. In this narrative review, we describe the prevalence of malnutrition and its clinical consequences among surgical patients in low- and middle-income countries, suggest potential measures to improve nutrition management, and discuss the necessity of considering nutrition management as a component of surgical care capacity...
May 16, 2017: Tropical Medicine & International Health: TM & IH
https://www.readbyqxmd.com/read/28510988/barriers-to-obstetric-fistula-treatment-in-low-income-countries-a-systematic-review
#11
REVIEW
Rachel Bach, Charlotte Warren, Zoe Baker, Ben Bellows
OBJECTIVES: To identify the barriers that women living with fistula in low-income countries face, preventing them from seeking care, reaching medical centers, and receiving appropriate care. METHODS: Bibliographic databases, grey literature, journals, and network and organization websites were searched in English and French from June to July 2014 using key search terms and specific inclusion and exclusion criteria for discussion of barriers to fistula treatment...
May 16, 2017: Tropical Medicine & International Health: TM & IH
https://www.readbyqxmd.com/read/28464403/seasonal-variation-in-child-mortality-in-rural-guinea-bissau
#12
Bibi Uhre Nielsen, Stine Byberg, Peter Aaby, Amabelia Rodrigues, Christine Stabell Benn, Ane Baerent Fisker
OBJECTIVES: In many African countries, child mortality is higher in the rainy season than in the dry season. We investigated the effect of season on child mortality by time periods, sex, and age in rural Guinea-Bissau. METHODS: Bandim health project follows children under-five in a health and demographic surveillance system in rural Guinea-Bissau. We compared the mortality in the rainy season (June to November) between 1990 and 2013 with the mortality in the dry season (December to May) in Cox proportional hazards models providing rainy versus dry season mortality rate ratios (r/d-mrr)...
May 2, 2017: Tropical Medicine & International Health: TM & IH
https://www.readbyqxmd.com/read/28449385/linkage-to-hiv-care-after-home-based-hiv-counselling-and-testing-in-sub-saharan-africa-a-systematic-review
#13
REVIEW
Eugene Ruzagira, Kathy Baisley, Anatoli Kamali, Samuel Biraro, Heiner Grosskurth
BACKGROUND: Home-based HIV counselling and testing (HBHCT) has the potential to increase HIV testing uptake in sub-Saharan Africa (SSA), but data on linkage to HIV care after HBHCT are scarce. We conducted a systematic review of linkage to care after HBHCT in SSA. METHODS: Five databases were searched for studies published between 1st January 2000 and 19th August 2016 that reported on linkage to care among adults newly identified with HIV infection through HBHCT...
April 27, 2017: Tropical Medicine & International Health: TM & IH
https://www.readbyqxmd.com/read/28449358/incident-rate-and-risk-factors-for-tuberculosis-among-patients-with-type-2-diabetes-retrospective-cohort-study-in-shanghai-china
#14
Hanbi Qiu, Yan Shi, Yanyun Li, Xin Shen, Rui Li, Qundi Yang, Qichao Pan, Fei Yan
OBJECTIVE: To examine the incident rate of tuberculosis (TB) and its associates among adults with type 2 diabetes in Shanghai, China. METHODS: We conducted a retrospective cohort study among 170,399 type 2 diabetes patients aged ≥18 years who were registered in Shanghai Community-Based Diabetes Management System between 2004 and 2009. Their TB status was tracked until December 31, 2014. Cox regression was performed to identify the risk factors for TB RESULTS: We documented 785 new TBcases during 654,977 person-years of follow-up...
April 27, 2017: Tropical Medicine & International Health: TM & IH
https://www.readbyqxmd.com/read/28449332/behavioural-disinhibition-in-the-general-population-during-the-antiretroviral-therapy-roll-out-in-sub-saharan-africa-systematic-review-and-meta-analysis
#15
REVIEW
Eva M Legemate, Jan A C Hontelez, Caspar W N Looman, Sake J De Vlas
OBJECTIVES: Improved life expectancy and reduced transmission probabilities due to ART may result in behavioural disinhibition - i.e. an increase in sexual risk behaviour in response to a perceived lower risk of HIV. We examined trends in sexual risk behaviour in the general population of sub-Saharan African countries 1999 - 2015. METHODS: We systematically reviewed scientific literature of sexual behaviour, and reviewed trends in Demographic and Health Surveys...
April 27, 2017: Tropical Medicine & International Health: TM & IH
https://www.readbyqxmd.com/read/28449319/comparison-of-administrative-and-survey-data-for-estimating-vitamin-a-supplementation-and-deworming-coverage-of-children-under-five-years-of-age-in-sub-saharan-africa
#16
Amynah Janmohamed, David Doledec
OBJECTIVE: To compare administrative coverage data to results from household coverage surveys for vitamin A supplementation (VAS) and deworming campaigns conducted during 2010-2015 in 12 African countries. METHODS: Paired t-tests examined differences between administrative and survey coverage for 52 VAS and 34 deworming dyads. Independent t-tests measured VAS and deworming coverage differences between data sources for door-to-door and fixed-site delivery strategies and VAS coverage differences between 6 to 11 and 12 to 59-month age groups...
April 27, 2017: Tropical Medicine & International Health: TM & IH
https://www.readbyqxmd.com/read/28449318/screening-diagnosis-and-management-of-human-cysticercosis-and-t-solium-taeniasis-technical-recommendations-by-the-cohemi-project-study-group
#17
Lorenzo Zammarchi, Maurizio Bonati, Marianne Strohmeyer, Marco Albonico, Ana Requena-Méndez, Zeno Bisoffi, Alessandra Nicoletti, Hector H García, Alessandro Bartoloni
Neurocysticercosis, the central nervous system's localized form of cysticercosis, is considered to be the leading cause of epilepsy in the developing world. In Europe, the disease mainly imported and affects both immigrants and travellers. However, autochthonous cases of cysticercosis in low-endemic countries could also originate from T. solium carriers (migrants or travellers) who acquired taeniasis overseas. Management of cysticercosis is a challenge for European healthcare providers since they are often hardly aware of this infection and have little familiarity in managing this disease...
April 27, 2017: Tropical Medicine & International Health: TM & IH
https://www.readbyqxmd.com/read/28449238/exposure-response-relationship-of-neighbourhood-sanitation-and-children-s-diarrhea
#18
Youngmee Tiffany Jung, Wendy Lou, Yu-Ling Cheng
OBJECTIVES: To assess the association of neighbourhood sanitation coverage with under-five children's diarrheal morbidity, and to evaluate its exposure-response relationship. METHODS: We used the Demographic and Health Surveys (DHS) of 29 developing countries in sub-Saharan Africa and South Asia, conducted between 2010 and 2014. The primary outcome was 2-week incidence of diarrhea in children under 5 years of age (N=300426). We conducted three-level logistic regression analyses and applied cubic splines to assess the trend between neighbourhood-level coverage of improved household sanitation and diarrheal morbidity...
April 27, 2017: Tropical Medicine & International Health: TM & IH
https://www.readbyqxmd.com/read/28449198/systematic-review-of-sex-work-interventions-in-sub-saharan-africa-examining-combination-prevention-approaches
#19
REVIEW
George Awungafac, Therese Delvaux, Bea Vuylsteke
OBJECTIVE: The incidence of HIV and sexually transmitted infections is disproportionately high among sex workers (SW). We aimed to update the evidence on the effectiveness of SW interventions in sub-Saharan Africa and to provide more insights into combination prevention. METHODS: The Systematic review followed PRISMA guidelines in a search of PUBMED and POPLINE for peer-reviewed literature published between 1 January 2000 and 22 July 2016 (registration number on PROSPERO: CRD42016042529)...
April 27, 2017: Tropical Medicine & International Health: TM & IH
https://www.readbyqxmd.com/read/28407452/uptake-and-performance-of-prevention-of-mother-to-child-transmission-and-early-infant-diagnosis-in-pregnant-hiv-infected-women-and-their-exposed-infants-at-seven-health-centres-in-addis-ababa-ethiopia
#20
Marshet Girma, Rahel Wendaferash, Hailu Shibru, Yemane Berhane, Michael Hoelscher, Arne Kroidl
OBJECTIVE: To assess the uptake of WHO-recommended PMTCT procedures in Ethiopia's health services. METHODS: Prospective observational study of HIV-positive pregnant mothers and their newborns attending PMTCT services at seven health centres in Addis Ababa. Women were recruited during antenatal care and followed-up with their newborns at delivery, day 6 and week 6 postpartum. Retention to PMCTC procedures, self-reported ART adherence, and HIV infant outcome were assessed...
April 13, 2017: Tropical Medicine & International Health: TM & IH
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