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Tropical Medicine & International Health: TM & IH

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https://www.readbyqxmd.com/read/28319300/children-s-mouthing-of-soil-contaminated-objects-is-associated-with-environmental-enteropathy
#1
Tomohiko Morita, Jamie Perin, Lauren Oldja, Shwapon Biswas, R Bradley Sack, Shahnawaz Ahmed, Rashidul Haque, Nurul Amin Bhuiyan, Tahmina Parvin, Sazzadul Islam Bhuyian, Mahmuda Akter, Kaisar A Talukder, Shahnaij Mohammad, Abu G Faruque, Christine Marie George
OBJECTIVE: To investigate the relationship between children's mouthing behaviors, diarrhea, and environmental enteropathy. METHODS: Prospective cohort study of 216 children ≤ 30 months of age in rural Bangladesh. Mouthing contacts with soil and food and objects with visible soil was measured by five-hour structured observation. Stool was analyzed for four fecal markers of intestinal inflammation: alpha-1-antitrypsin, myeloperoxidase, neopterin, and calprotectin...
March 20, 2017: Tropical Medicine & International Health: TM & IH
https://www.readbyqxmd.com/read/28319296/joint-effects-of-climate-variability-and-socio-ecological-factors-on-dengue-transmission-epidemiological-evidence
#2
REVIEW
Rokeya Akter, Wenbiao Hu, Suchithra Naish, Shahera Banu, Shilu Tong
OBJECTIVE: To assess the epidemiological evidence on the joint effects of climate variability and socio-ecological factors on dengue transmission. METHODS: Following PRISMA guidelines, a detailed literature search was conducted in PubMed, Web of Science and Scopus. Peer-reviewed, freely available and full text articles, considering both climate and socio-ecological factors in relation to dengue, published in English from January 1993 to October 2015 were included in this review...
March 20, 2017: Tropical Medicine & International Health: TM & IH
https://www.readbyqxmd.com/read/28294472/knowledge-and-practice-regarding-dengue-and-chikungunya-a-cross-sectional-study-among-healthcare-workers-and-community-in-northern-tanzania
#3
Debora C Kajeguka, Rachelle E Desrochers, Rose Mwangi, Maseke R Mgabo, Michael Alifrangis, Reginald A Kavishe, Franklin W Mosha, Manisha A Kulkarni
OBJECTIVE: To investigate knowledge and prevention practices regarding dengue and chikungunya amongst community members, as well as knowledge, treatment and diagnostic practices among healthcare workers. METHOD: We conducted a cross-sectional survey with 125 community members and 125 healthcare workers from 13 health facilities in six villages in the Hai district of Tanzania. A knowledge score was generated based on participant responses to a structured questionnaire, with a score of 40 or higher (out of 80 and 50 total scores for community members and healthcare workers, respectively) indicating good knowledge...
March 13, 2017: Tropical Medicine & International Health: TM & IH
https://www.readbyqxmd.com/read/28278358/health-seeking-behaviour-and-health-expenditure-in-adults-aged-45-years-and-older-in-china-2011-2013
#4
Jiasen Li, Xing Lin Feng
OBJECTIVES: To provide an assessment of China's progress to universal health care from the perspective of people-centred care. METHODS: We obtained data on 28,103 participants from the China Health and Retirement Longitudinal Study during 2011-2013. Logistic regressions and generalized linear models were used to analyse care-seeking behaviours and medical expenditure. RESULTS: Insurance coverage was 95.5% in 2013. Nearly 60% subjects in need of medical care were self-medicated...
March 9, 2017: Tropical Medicine & International Health: TM & IH
https://www.readbyqxmd.com/read/28278357/factors-associated-with-the-health-and-cognition-of-6-8-year-old-children-in-kwazulu-natal-south-africa
#5
Oluwakemi R Ajayi, Glenda Matthews, Myra Taylor, Jane Kvalsvig, Leslie L Davidson, Shuaib Kauchali, Claude A Mellins
OBJECTIVE: To investigate 6-8 year-old children's health, nutritional status and cognitive development in a predominantly rural area of KwaZulu-Natal, South Africa. METHODS: Cohort study of 1383 children investigating the association of demographic variables (area of residence, sex, pre- school education, HIV status, height for age and haemoglobin level) and family variables (socioeconomic status, maternal and paternal level of education), with children's cognitive performance...
March 9, 2017: Tropical Medicine & International Health: TM & IH
https://www.readbyqxmd.com/read/28278352/mobile-phone-based-interactive-voice-response-as-a-tool-for-improving-access-to-healthcare-in-remote-areas-in-ghana-an-evaluation-of-user-experiences
#6
J Brinkel, J May, R Krumkamp, M Lamshöft, B Kreuels, E Owusu-Dabo, A Mohammed, A Bonacic Marinovic, P Dako-Gyeke, A Krämer, J N Fobil
OBJECTIVES: To investigate and determine the factors that enhanced or constituted barriers to the acceptance of an mHealth system which was piloted in Asante-Akim North District of Ghana to support healthcare of children. METHODS: Four semi-structured focus group discussions were conducted with a total of 37 mothers. Participants were selected from a study population of mothers who subscribed to a pilot mHealth system which used an interactive voice response for its operations...
March 9, 2017: Tropical Medicine & International Health: TM & IH
https://www.readbyqxmd.com/read/28244191/does-targeting-children-with-hygiene-promotion-messages-work-the-effect-of-handwashing-promotion-targeted-at-children-on-diarrhoea-soil-transmitted-helminth-infections-and-behaviour-change-in-low-and-middle-income-countries
#7
REVIEW
Julie A Watson, Jeroen H J Ensink, Monica Ramos, Prisca Benelli, Elizabeth Holdsworth, Robert Dreibelbis, Oliver Cumming
OBJECTIVES: To synthesise evidence on the effect of handwashing promotion interventions targeting children, on diarrhoea, soil-transmitted helminth infection and handwashing behaviour, in low and middle income country settings. METHODS: A systematic review of the literature was performed by searching 8 databases and reference lists were hand searched for additional articles. Studies were reviewed for inclusion according to pre-defined inclusion criteria and the quality of all studies was assessed...
February 28, 2017: Tropical Medicine & International Health: TM & IH
https://www.readbyqxmd.com/read/28244176/can-infant-vaccination-prevent-pneumococcal-meningitis-outbreaks-in-sub-saharan-africa
#8
EDITORIAL
James M Stuart
The WHO Strategic Advisory Group of Experts is reviewing the technical evidence to inform policy on optimal use of infant pneumococcal conjugate vaccines (PCV)(1). Since 2010, multivalent vaccines (PCV-10, PCV-13) have been successfully introduced with the support of Gavi the Vaccine Alliance into infant immunisation programmes across the developing world(2). One recommended schedule consists of three doses under the age of 6 months (3+0), with the aim of providing maximum protection to infants, the age group at highest risk of pneumococcal disease(3)...
February 28, 2017: Tropical Medicine & International Health: TM & IH
https://www.readbyqxmd.com/read/28218991/follow-up-of-surgically-treated-patients-with-cystic-echinococcosis-can-novel-recombinant-antigens-compete-with-imaging-analysis-of-a-patient-cohort
#9
Marija Stojkovic, Hans-Micha Adt, Kerstin Rosenberger, Ghalia Boubaker, Ana Hernandez-Gonzalez, Thomas Junghanss, Marcel Zwahlen, Mar Siles-Lucas
OBJECTIVE: To compare the performance of two novel recombinant antigens (EgP29, 2B2t) with imaging in a well-defined cohort of surgically treated cystic echinococcosis (CE) patients to determine whether serology reflects surgical cure as defined by imaging. METHODS: From a cohort of 223 CE-confirmed patients of a national clinical center for echinococcosis, 36 surgically treated patients were eligible for analysis. Sera were tested by enzyme-linked immunosorbent assay (ELISA) for specific IgG and IgG4 antibodies against the EgP29 and 2B2t antigens...
February 20, 2017: Tropical Medicine & International Health: TM & IH
https://www.readbyqxmd.com/read/28214384/placental-pathology-in-hiv-infection-at-term-a-comparison-with-hiv-uninfected-women
#10
Emma Kalk, Pawel Schubert, Julie A Bettinger, Mark F Cotton, Monika Esser, Amy Slogrove, Colleen A Wright
OBJECTIVES: To describe and correlate placental characteristics from pregnancies in HIV-infected and HIV-negative women with maternal and infant clinical and immunological data. METHODS: Prospective descriptive study of placentas from term, uncomplicated vaginal births in a cohort of HIV-infected (n=120) and HIV-negative (n=103) women in Cape Town, South Africa. Microscopic and macroscopic features were used to determine pathological cluster diagnoses. The majority of HIV-infected women received some form of drug treatment for the prevention of vertical transmission of HIV...
February 18, 2017: Tropical Medicine & International Health: TM & IH
https://www.readbyqxmd.com/read/28214373/improved-detection-of-zika-virus-rna-in-human-and-animal-specimens-by-a-novel-highly-sensitive-and-specific-real-time-rt-pcr-assay-targeting-the-5-untranslated-region-of-zika-virus
#11
Jasper Fuk-Woo Chan, Cyril Chik-Yan Yip, Kah-Meng Tee, Zheng Zhu, Jessica Oi-Ling Tsang, Kenn Ka-Heng Chik, Terance Gi-Wai Tsang, Chris Chung-Sing Chan, Vincent Kwok-Man Poon, Siddharth Sridhar, Feifei Yin, Ivan Fan-Ngai Hung, Sandy Ka-Yee Chau, Anna Jinxia Zhang, Kwok-Hung Chan, Kwok-Yung Yuen
OBJECTIVE AND METHOD: We developed and evaluated five novel real-time RT-PCR assays targeting conserved regions in the 5'-untranslated region (5'-UTR), envelope (E'), non-structural protein 2A (NS2A), NS5, and 3'-UTR of the ZIKV genome. RESULTS: The ZIKV-5'-UTR assay exhibited the lowest in-vitro limit of detection (5-10 RNA copies/reaction and 3.0×10(-1) plaque-forming units/ml). Compared to the modified version of a widely adopted RT-PCR assay targeting the ZIKV-E gene, the ZIKV-5'-UTR assay showed better sensitivity in human clinical specimens, and representative mouse specimens, including many organs which are known to be involved in human ZIKV infection but difficult to obtain in clinical settings...
February 18, 2017: Tropical Medicine & International Health: TM & IH
https://www.readbyqxmd.com/read/28196301/guinea-worm-infection-in-northern-nigeria-reflections-on-a-disease-approaching-eradication
#12
Brian Greenwood, Alice Greenwood, Andrew Bradley
Global eradication of the Guinea worm (Dracunculus medinensis) is near, although perhaps delayed a little by the discovery of a transmission cycle in dogs. It is, therefore, an appropriate time to reflect on the severe impact of this infection on the life of the communities where it was endemic prior to the start of the global eradication programme in 1981. From 1971-74, we conducted a series of unpublished studies on Guinea worm in a group of villages in Katsina State, northern Nigeria, where the infection was highly endemic...
February 14, 2017: Tropical Medicine & International Health: TM & IH
https://www.readbyqxmd.com/read/28196298/human-to-human-transmission-of-brucella-a-systematic-review
#13
REVIEW
Felipe F Tuon, Regina B Gondolfo, Natacha Cerchiari
OBJECTIVE: The most common form of transmitting human brucellosis is through contaminated food or direct contact with infected animals. Human-to-human transmission (HHT) has been described as isolated case reports. The aim of this systematic review was to describe all cases of HHT of human brucellosis reported in the medical literature. METHODS: A literature search was conducted using PubMed, Scopus and Scielo databases using specific search terms published until March 2016...
February 14, 2017: Tropical Medicine & International Health: TM & IH
https://www.readbyqxmd.com/read/28187247/prevalence-and-correlates-of-antibiotic-sharing-in-the-philippines-antibiotic-misconceptions-and-community-level-access-to-nonmedical-sources-of-antibiotics
#14
Daniel Barber, Efren Casquejo, Purita L Ybañez, Magdaleno T Pinote, Luz Casquejo, Lucia S Pinote, Magdalena Estorgio, April M Young
OBJECTIVE: To identify sociodemographic, knowledge, and attitudinal correlates to antibiotic-sharing among a community-based sample of adults (age 18 and older) in a low-income setting of the Philippines and to explore community-level data on informal antibiotic distribution in roadside stands (i.e., sari-sari stands). METHODS: Participants (n=307) completed self-administered surveys. Correlates to antibiotic sharing were assessed using logistic regression with Firth's bias-adjusted estimates...
February 10, 2017: Tropical Medicine & International Health: TM & IH
https://www.readbyqxmd.com/read/28173608/prevalence-and-risk-factors-for-scrub-typhus-in-south-india
#15
Paul Trowbridge, Divya P, Prasanna S Premkumar, George M Varghese
OBJECTIVE: To determine the prevalence and risk factors of scrub typhus in Tamil Nadu, South India. METHODS: We performed a clustered seroprevalence study of the areas around Vellore. All participants completed a risk factor survey, with seropositive and seronegative participants acting as cases and controls, respectively, in a risk factor analysis. After univariate analysis, variables found to be significant underwent multivariate analysis. RESULTS: Of 721 people participating in this study, 31...
February 7, 2017: Tropical Medicine & International Health: TM & IH
https://www.readbyqxmd.com/read/28170120/physical-function-grip-strength-and-frailty-in-people-living-with-hiv-in-sub-saharan-africa-systematic-review
#16
REVIEW
Charlotte Bernard, François Dabis, Nathalie de Rekeneire
OBJECTIVE: To present the current knowledge on physical function, grip strength and frailty in HIV-infected patients living in sub-Saharan Africa, where the phenomenon is largely underestimated. METHODS: A systematic search was conducted on MEDLINE, Scopus and African Index Medicus. We reviewed articles on sub-Saharan African people living with HIV (PLHIV) >18 years old, published until November 2016. RESULTS: Of 537 articles, 12 were conducted in six African countries and included in this review...
February 7, 2017: Tropical Medicine & International Health: TM & IH
https://www.readbyqxmd.com/read/28168834/pyrethroid-and-ddt-tolerance-of-anopheles-gambiae-s-l-from-sengerema-district-an-area-of-intensive-pesticide-usage-in-northwestern-tanzania
#17
Anita Philbert, Sylvester Leonard Lyantagaye, Gabriele Pradel, Che Julius Ngwa, Gamba Nkwengulila
OBJECTIVE: To assess the susceptibility status of malaria vectors to pyrethroids and dichlorodiphenyltrichloroethane (DDT), characterize the mechanisms underlying resistance, and to evaluate the role of agro-chemical use in resistance selection among malaria vectors in Sengerema agro ecosystem zone, Tanzania. METHODS: Mosquito larvae were collected from farms and reared to obtain adults. The susceptibility status of An. gambiae s.l. was assessed using WHO bioassay tests to permethrin, deltamethrin, lambdacyhalothrin, etofenprox, cyfluthrin, and DDT...
February 7, 2017: Tropical Medicine & International Health: TM & IH
https://www.readbyqxmd.com/read/28164415/escherichia-coli-contamination-of-child-complementary-foods-and-association-with-domestic-hygiene-in-rural-bangladesh
#18
Sarker Masud Parvez, Laura Kwong, Musarrat Jabeen Rahman, Ayse Ercumen, Amy J Pickering, Probir K Ghosh, Md Zahidur Rahman, Kishor Kumar Das, Stephen P Luby, Leanne Unicomb
OBJECTIVE: To determine the frequency and concentration of Escherichia coli in child complementary food and its association with domestic hygiene practices in rural Bangladesh. METHOD: A total of 608 households with children <2 years were enrolled. We collected stored complementary food samples, performed spot checks on domestic hygiene and measured ambient temperature in the food storage area. Food samples were analysed using the IDEXX most probable number (MPN) method with Colilert-18 media to enumerate E...
February 6, 2017: Tropical Medicine & International Health: TM & IH
https://www.readbyqxmd.com/read/28151567/first-molecular-epidemiology-of-entamoeba-histolytica-e-dispar-and-e-moshkovskii-infections-in-yemen-different-species-specific-associated-risk-factors
#19
Mona A Al-Areeqi, Hany Sady, Hesham M Al-Mekhlafi, Tengku Shahrul Anuar, Abdulelah H Al-Adhroey, Wahib M Atroosh, Salwa Dawaki, Fatin Nur Elyana, Nabil A Nasr, Init Ithoi, Yee-Ling Lau, Johari Surin
OBJECTIVES: To investigate the molecular epidemiology of Entamoeba histolytica, E. dispar and E. moshkovskii infections among rural communities in Yemen. METHODS: In a community-based study, faecal samples were collected from 605 participants and examined by wet mount, formalin-ether sedimentation, trichrome staining and nested multiplex PCR techniques. Demographic, socio-economic and environmental information was collected using a pre-tested questionnaire. RESULTS: Overall, 324 (53...
February 2, 2017: Tropical Medicine & International Health: TM & IH
https://www.readbyqxmd.com/read/28151566/efficacy-of-artesunate-sulphadoxine-pyrimethamine-and-artemether-lumefantrine-and-dhfr-and-dhps-mutations-in-somalia-evidence-for-updating-the-malaria-treatment-policy
#20
Marian Warsame, Abdikarim Hussein Hassan, Abdillahi Mohamed Hassan, Abdulkadir Mohamed Arale, Ali Mohamed Jibril, Said Abdulkadir Mohamud, Amy Barrette, Abdikarim Yusuf Muse, Fahmi Essa Yusuf, Rania A Nada, Jamal Ghilan Hefzullah Amran
OBJECTIVE: To determine the therapeutic efficacy of artesunate + sulphadoxine/pyrimethamine (AS + SP) and artemether + lumefantrine (AL), and to investigate the presence of molecular mutations associated with resistance, to inform national malaria treatment policy. METHODS: One-arm prospective studies were conducted in three study sites in Somalia in 2013 and 2015 to evaluate the efficacy of AS + SP and AL among patients with uncomplicated falciparum malaria. Outcomes included clinical and parasitological response over 28 days, and the presence of dihydrofolate reductase (dfhr) and dihydropteroate synthase (dhps) and mutations...
February 2, 2017: Tropical Medicine & International Health: TM & IH
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