Daniel Vidal-Correoso, Sandra V Mateo, Ana M Muñoz-Morales, Fernando Lucas-Ruiz, Marta Jover-Aguilar, Felipe Alconchel, Laura Martínez-Alarcón, Sara Sánchez-Redondo, Vanesa Santos, Víctor López-López, Antonio Ríos-Zambudio, Pedro Cascales, José Antonio Pons, Pablo Ramírez, Pablo Pelegrín, Héctor Peinado, Alberto Baroja-Mazo
BACKGROUND: Liver transplantation (LT) is crucial for end-stage liver disease patients, but organ shortages persist. Donation after circulatory death (DCD) aims to broaden the donor pool but presents challenges. Complications like acute rejection, hepatic artery thrombosis, and biliary issues still impact posttransplant prognosis. Biomarkers, including extracellular vesicles (EVs) and microRNAs (miRNAs), show promise in understanding and monitoring posttransplant events. This study explores the role of EVs and their miRNA cargo in LT, including their potential as diagnostic tools...
April 5, 2024: Transplantation