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https://www.readbyqxmd.com/read/29779869/genotypic-characteristics-and-their-association-with-phenotypic-characteristics-of-hereditary-medullary-thyroid-carcinoma-in-korea
#1
Kyong Yeun Jung, Seok-Mo Kim, Min Joo Kim, Sun Wook Cho, Bup-Woo Kim, Yong Sang Lee, Jong Ju Jeong, Kee-Hyun Nam, Woong Youn Chung, Kyu Eun Lee, Eun-Jae Chung, Hyo Jeong Kim, Do Joon Park, Myung-Whun Sung, Cheong Soo Park, Bo Young Cho, Young Joo Park, Hang-Seok Chang
BACKGROUND: Hereditary medullary thyroid carcinoma can present as a part of multiple endocrine neoplasia syndrome by rearranged during transfection gene mutation. We evaluated the prevalence of rearranged during transfection gene mutation in patients who have medullary thyroid carcinoma and the correlations of genotype with medullary thyroid carcinoma, pheochromocytoma, and hyperparathyroidism according to the revised American Thyroid Association risk level. METHODS: A total of 331 patients were diagnosed with medullary thyroid carcinoma, 172 of whom were tested for the rearranged during transfection germline mutation by sequencing of exon 8, 10, 11, and 13-16...
May 17, 2018: Surgery
https://www.readbyqxmd.com/read/29779868/new-onset-diabetes-after-pancreatoduodenectomy-a-systematic-review-and-meta-analysis
#2
Lianne Scholten, Timothy H Mungroop, Simone A L Haijtink, Yama Issa, L Bengt van Rijssen, Bas Groot Koerkamp, Casper H van Eijck, Olivier R Busch, J Hans DeVries, Marc G Besselink
BACKGROUND: Pancreatoduodenectomy may lead to new-onset diabetes mellitus, also known as type 3c diabetes, but the exact risk of this complication is unknown. The aim of this review was to assess the risk of new-onset diabetes mellitus after pancreatoduodenectomy. METHODS: A literature search was performed in PubMed, Embase (Ovid), and the Cochrane Library for English articles published from March 1993 until March 2017 (PROSPERO registry number: CRD42016039784)...
May 17, 2018: Surgery
https://www.readbyqxmd.com/read/29778250/surgical-management-of-intraductal-papillary-mucinous-neoplasm-with-main-duct-involvement-an-international-expert-survey-and-case-vignette-study
#3
Lianne Scholten, Nadine C M van Huijgevoort, Marco J Bruno, Carlos Fernandez-Del Castillo, Sohei Satoi, Alain Sauvanet, Christopher Wolfgang, Paul Fockens, Suresh T Chari, Marco Del Chiaro, Jeanin E van Hooft, Marc G Besselink
BACKGROUND: The risk of invasive cancer in resected intraductal papillary mucinous neoplasm with main pancreatic duct involvement is 33%-60%. Most guidelines, therefore, advise resection of main duct intraductal papillary mucinous neoplasm and mixed type intraductal papillary mucinous neoplasm in surgically fit patients, although advice on the surgical strategy (partial or total pancreatectomy) differs. We performed a survey amongst international experts to guide the design of future studies and help to prepare for a single international set of guidelines...
May 16, 2018: Surgery
https://www.readbyqxmd.com/read/29776597/the-role-of-fdg-pet-in-detecting-rejection-after-liver-transplantation
#4
Ashley M Watson, Neal Bhutiani, Prejesh Philips, Eric G Davis, Mary Eng, Robert M Cannon, Christopher M Jones
BACKGROUND: The activation and increased metabolic activity of T cells in acute cellular rejection could allow fluoro-2-deoxyglucose positron emission tomography to be utilized for detection of acute cellular rejection. The objective of this study was to evaluate the effectiveness of fluoro-2-deoxyglucose positron emission tomography in detecting acute cellular rejection in the clinical setting. METHODS: Fluoro-2-deoxyglucose positron emission tomography studies were performed on 88 orthotopic liver transplant patients at 7 and 17 days postoperatively (first positron emission tomography and second positron emission tomography, respectively)...
May 15, 2018: Surgery
https://www.readbyqxmd.com/read/29776596/surgical-procedures-in-health-professional-shortage-areas-impact-of-a-surgical-incentive-payment-plan
#5
Adrian Diaz, Katiuscha Merath, Fabio Bagante, Qinyu Chen, Ozgur Akgul, Eliza Beal, Jay Idrees, Griffin Olsen, Faiz Gani, Timothy M Pawlik
INTRODUCTION: The Affordable Care Act established a Center for Medicare/Medicaid Services based 10% reimbursement bonus for general surgeons in Health Professional Shortage Areas. We sought to assess the impact of the Affordable Care Act Surgery Incentive Payment on surgical procedures performed in Health Professional Shortage Areas. METHODS: Hospital utilization data from the California Office of Statewide Health Planning and Development between January 1, 2006, and December 31, 2015, were used to categorize hospitals according to Health Professional Shortage Area location...
May 15, 2018: Surgery
https://www.readbyqxmd.com/read/29773360/quality-of-cells-in-autologous-cell-transplantation-for-critical-limb-ischemia
#6
LETTER
Tetsuji Fujita
No abstract text is available yet for this article.
May 14, 2018: Surgery
https://www.readbyqxmd.com/read/29759300/decreased-contractile-response-of-peripheral-arterioles-to-serotonin-after-cpb-in-patients-with-diabetes
#7
Sharif A Sabe, Jun Feng, Yuhong Liu, Laura A Scrimgeour, Afshin Ehsan, Frank W Sellke
BACKGROUND: Regulation of coronary vasomotor tone by serotonin is significantly changed after cardioplegic arrest and reperfusion. The current study investigates whether cardiopulmonary bypass may also affect peripheral arteriolar response to serotonin in patients with or without diabetes. METHODS: Human peripheral microvessels (90-180 µm diameter) were dissected from harvested skeletal muscle tissues from diabetic and non-diabetic patients before and after cardiopulmonary bypass and cardiac surgery (n = 8/group)...
May 11, 2018: Surgery
https://www.readbyqxmd.com/read/29754978/risk-stratification-using-a-novel-liver-functional-reserve-score-of-combination-prothrombin-time-international-normalized-ratio-to-albumin-ratio-and-albumin-in-patients-with-hepatocellular-carcinoma
#8
Koichiro Haruki, Hiroaki Shiba, Nobuhiro Saito, Takashi Horiuchi, Yoshihiro Shirai, Yuki Fujiwara, Kenei Furukawa, Taro Sakamoto, Katsuhiko Yanaga
BACKGROUND: Liver function in patients with hepatocellular carcinoma is generally graded according to the Child-Pugh system; however, some variables in the Child-Pugh grade are subjective. We developed a novel, objective score called the prothrombin time-international normalized ratio to albumin ratio. The aim of this study was to evaluate the prognostic value of this new score in patients with hepatocellular carcinoma after hepatic resection. METHODS: The study comprised 199 patients who underwent elective hepatic resection for hepatocellular carcinoma between January 2003 and December 2014...
May 10, 2018: Surgery
https://www.readbyqxmd.com/read/29753461/hepatic-venous-pressure-gradient-after-portal-vein-embolization-an-accurate-predictor-of-future-liver-remnant-hypertrophy
#9
Kayvan Mohkam, Agnès Rode, Benjamin Darnis, Anne-Frédérique Manichon, Loïc Boussel, Christian Ducerf, Philippe Merle, Mickaël Lesurtel, Jean-Yves Mabrut
BACKGROUND: The impact of portal hemodynamic variations after portal vein embolization on liver regeneration remains unknown. We studied the correlation between the parameters of hepatic venous pressure measured before and after portal vein embolization and future hypertrophy of the liver remnant after portal vein embolization. METHODS: Between 2014 and 2017, we reviewed patients who were eligible for major hepatectomy and who had portal vein embolization. Patients had undergone simultaneous measurement of portal venous pressure and hepatic venous pressure gradient before and after portal vein embolization by direct puncture of portal vein and inferior vena cava...
May 9, 2018: Surgery
https://www.readbyqxmd.com/read/29753460/synthetic-high-density-lipoprotein-nanoconjugate-targets-neuroblastoma-stem-cells-blocking-migration-and-self-renewal
#10
Chitra Subramanian, Peter T White, Rui Kuai, Avinaash Kalidindi, Valerie P Castle, James J Moon, Barbara N Timmermann, Anna Schwendeman, Mark S Cohen
BACKGROUND: Pathways critical for neuroblastoma cancer stem cell function are targeted by 4,19,27-triacetyl withalongolide A (WGA-TA). Because neuroblastoma cells and their cancer stem cells highly overexpress the scavenger receptor class B type 1 receptor that binds to synthetic high-density lipoprotein, we hypothesized that a novel mimetic synthetic high-density lipoprotein nanoparticle would be an ideal carrier for the delivery of 4,19,27-triacetyl withalongolide to neuroblastoma and neuroblastoma cancer stem cells...
May 9, 2018: Surgery
https://www.readbyqxmd.com/read/29751970/does-liver-transplant-offer-a-better-survival-benefit-than-margin-negative-resection-in-patients-with-small-unifocal-hepatocellular-carcinoma
#11
LETTER
Tian Yang, Jiong-Jie Yu, Li-Yang Sun, Bing Quan
No abstract text is available yet for this article.
May 9, 2018: Surgery
https://www.readbyqxmd.com/read/29751966/outcomes-in-nursing-home-patients-with-traumatic-brain-injury
#12
Stephanie N Lueckel, Cyrus M Kosar, Joan M Teno, Sean F Monaghan, Daithi S Heffernan, William G Cioffi, Kali S Thomas
BACKGROUND: Traumatic brain injury is a leading cause of death and disability in the United States. In survivors, traumatic brain injury remains a leading contributor to long-term disability and results in many patients being admitted to skilled nursing facilities for postacute care. Despite this very large population of traumatic brain injury patients, very little is known about the long-term outcomes of traumatic brain injury survivors, including rates of discharge to home or risk of death in long-term nursing facilities...
May 9, 2018: Surgery
https://www.readbyqxmd.com/read/29751964/letter-to-editor-thyroid-lobectomy-is-not-sufficient-for-t2-papillary-thyroid-cancers
#13
LETTER
Prakshi Chopra, Chitresh Kumar
No abstract text is available yet for this article.
May 9, 2018: Surgery
https://www.readbyqxmd.com/read/29751969/the-rate-of-false-positive-diagnosis-of-colorectal-liver-metastases-in-patients-undergoing-resection-with-the-development-of-a-novel-externally-validated-risk-score
#14
David J O'Reilly, James Hodson, Thomas W Pike, Ravi Marudanayagam, Robert P Sutcliffe, Paolo Muiesan, John Isaac, J Peter A Lodge, Darius F Mirza, Keith J Roberts
BACKGROUND: Diagnostic error in patients undergoing resection of colorectal liver metastases (CRLM) is unusual but exposes patients to unnecessary risks associated with treatment. The primary aim of this study was to determine the rate of and risk factors for a false-positive diagnosis of colorectal liver metastases in patients undergoing hepatic resection. The secondary aim was to develop and validate a risk score to predict a false-positive diagnosis. METHODS: Patients were identified from prospectively maintained databases...
May 8, 2018: Surgery
https://www.readbyqxmd.com/read/29751968/maintaining-oncologic-integrity-with-minimally-invasive-resection-of-pediatric-embryonal-tumors
#15
Hannah M Phelps, Gregory D Ayers, Josephine M Ndolo, Hannah L Dietrich, Katherine D Watson, Melissa A Hilmes, Harold N Lovvorn
BACKGROUND: Embryonal tumors arise typically in infants and young children and are often massive at presentation. Operative resection is a cornerstone in the multimodal treatment of embryonal tumors but potentially disrupts therapeutic timelines. When used appropriately, minimally invasive surgery can minimize treatment delays. The oncologic integrity and safety attainable with minimally invasive resection of embryonal tumors, however, remains controversial. METHODS: Query of the Vanderbilt Cancer Registry identified all children treated for intracavitary, embryonal tumors during a 15-year period...
May 8, 2018: Surgery
https://www.readbyqxmd.com/read/29751967/aneurysm-of-the-spleno-mesenteric-portal-confluence
#16
Servane Hamel, Paul Martre, Jean-Jacques Tuech, Lilian Schwarz
No abstract text is available yet for this article.
May 8, 2018: Surgery
https://www.readbyqxmd.com/read/29751965/de-labeling-of-%C3%AE-lactam-allergy-reduces-intraoperative-time-and-optimizes-choice-in-antibiotic-prophylaxis
#17
Yara Moussa, Joseph Shuster, Gilbert Matte, Andrew Sullivan, Robert H Goldstein, Dayle Cunningham, Moshe Ben-Shoshan, Gabriele Baldini, Francesco Carli, Christos Tsoukas
BACKGROUND: Suspected penicillin allergic individuals receive suboptimal non-β-lactams for intraoperative prophylaxis which may prolong operations and have negative clinical outcomes. We therefore studied if β-lactam de-labeling optimized choice of prophylactic antibiotics and improved intraoperative time efficiency. METHODS: A multistep approach was used. It included a risk assessment tool by an allergist, β-lactam skin testing and oral provocation. To determine the value of de-labeling, we appraised intraoperative antibiotic choices and correlated them with time to first incision...
May 8, 2018: Surgery
https://www.readbyqxmd.com/read/29747862/the-effect-of-insurance-type-on-access-to-inguinal-hernia-repair-under-the-affordable-care-act
#18
Walter Hsiang, Catherine McGeoch, Sarah Lee, William Cheung, Robert Becher, Kimberly A Davis, Kevin M Schuster
BACKGROUND: The expansion of Medicaid under the Affordable Care Act extended coverage to any individual with an income up to 138% of the federal poverty level. Our study of surgeon practice management investigated the impact of the type of insurance on access to elective inguinal hernia repair and the disparities in access between Medicaid expansion and nonexpansion states. METHODS: Practices of 240 hernia repair surgeons across 8 states were randomly selected from the American College of Surgeons Find a Surgeon Database...
May 7, 2018: Surgery
https://www.readbyqxmd.com/read/29739617/supporting-the-patient-through-supporting-the-surgeon-involved-in-an-adverse-event-and-or-a-medical-litigation
#19
EDITORIAL
David Xiang, Dimitrios Linos
No abstract text is available yet for this article.
May 5, 2018: Surgery
https://www.readbyqxmd.com/read/29731247/race-is-associated-with-completion-of-neoadjuvant-chemotherapy-for-breast-cancer
#20
Anne T Knisely, Alex D Michaels, J Hunter Mehaffey, Taryn E Hassinger, Elizabeth D Krebs, David R Brenin, Anneke T Schroen, Shayna L Showalter
BACKGROUND: Completion of prescribed neoadjuvant chemotherapy for breast cancer is paramount to patients obtaining full benefit from the treatment; however, factors affecting neoadjuvant chemotherapy completion are not known. We hypothesized that race is a predictor of completion of neoadjuvant chemotherapy in patients with breast cancer. METHODS: All patients with breast cancer treated with neoadjuvant chemotherapy 2009-2016 at a single institution were stratified by completion of neoadjuvant chemotherapy and by race...
May 3, 2018: Surgery
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