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Surgery

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https://www.readbyqxmd.com/read/28629653/do-hepatic-sided-tumors-require-more-extensive-resection-than-peritoneal-sided-tumors-in-patients-with-t2-gallbladder-cancer-results-of-a-retrospective-multicenter-study
#1
Woohyung Lee, Chi-Young Jeong, Jae Yool Jang, Young Hoon Kim, Young Hoon Roh, Kwan Woo Kim, Sung Hwa Kang, Myung Hee Yoon, Hyung Il Seo, Sung Pil Yun, Jeong-Ik Park, Bo-Hyun Jung, Dong Hoon Shin, Young Il Choi, Hyung Hwan Moon, Chong Woo Chu, Je Ho Ryu, Kwangho Yang, Young Mok Park, Soon-Chan Hong
BACKGROUND: Tumor location is a prognostic factor for survival in patients with T2 gallbladder cancer. However, the optimal extent of resection according to tumor location remains unclear. METHODS: We reviewed the records of 192 patients with T2 gallbladder cancer who underwent R0 or R1 resection at 6 institutions. Perioperative and oncologic outcomes were compared according to the extent of resection between hepatic-sided (n = 93) and peritoneal-sided (n = 99) tumors...
June 16, 2017: Surgery
https://www.readbyqxmd.com/read/28624178/liver-transplantation-in-patients-with-liver-metastases-from-neuroendocrine-tumors-a%C3%A2-systematic-review
#2
Dimitrios Moris, Diamantis I Tsilimigras, Ioannis Ntanasis-Stathopoulos, Eliza W Beal, Evangelos Felekouras, Spiridon Vernadakis, John J Fung, Timothy M Pawlik
BACKGROUND: Liver transplantation to treat neuroendocrine tumors, especially in the setting of diffuse liver involvement not amenable to operative resection remains controversial. We sought to perform a systematic review of the current literature to summarize data on patients undergoing liver transplantation with neuroendocrine tumors liver metastases as the indication. METHODS: A systematic review was conducted in accordance to the Preferred Reporting Items for Systematic reviews and Meta-Analysis guidelines...
June 14, 2017: Surgery
https://www.readbyqxmd.com/read/28624177/autophagy-can-alleviate-severe-burn-induced-damage-to-the-intestinal-tract-in-mice
#3
Duanyang Zhang, Wei Qiu, Peng Wang, Pan Zhang, Fang Zhang, PeiP Wang, Yong Sun
BACKGROUND: The present study was designed to examine the effect of autophagy and apoptosis on intestinal injury in mice after severe burns. METHODS: Kunming mice were subjected to third degree burns over 30% of the total body surface area. Damage to the intestine was assessed by examining changes in intestinal mucosal morphology, enzyme-linked immunosorbent assay of serum d-lactate, diamine oxidase, lipopolysaccharide, interleukin-6, and tumor necrosis factor α (marker of intestinal damage), hematoxylin and eosin staining, and Western blotting under 4 experimental conditions: control group, burn only (burn group), burn and administration of rapamycin to stimulate intestinal autophagy (rapamycin group), or burn and administration of 3-methyladenine to inhibit intestinal autophagy (3-methyladenine group)...
June 14, 2017: Surgery
https://www.readbyqxmd.com/read/28619666/treatment-of-rectal-cancer-in-the-east-and-west-should-it-be-different
#4
EDITORIAL
Songphol Malakorn, George J Chang
No abstract text is available yet for this article.
June 12, 2017: Surgery
https://www.readbyqxmd.com/read/28606726/patients-are-well-served-by-collis-gastroplasty-when-indicated
#5
Adam S Weltz, H Reza Zahiri, Udai S Sibia, Nan Wu, George T Fantry, Adrian E Park
BACKGROUND: Debate persists about the impact of a Collis gastroplasty on outcomes of antireflux operation. This study analyzed operative and quality of life outcomes from a series of 480 patients who underwent laparoscopic antireflux operation with a Collis gastroplasty reported to date. METHODS: A retrospective review was conducted to compare outcomes between patients undergoing laparoscopic antireflux operation with Collis gastroplasty versus without Collis gastroplasty at 2 large, foregut centers from October 2004 to December 2011 and July 2012 to September 2016...
June 9, 2017: Surgery
https://www.readbyqxmd.com/read/28606725/do-packed-red-blood-cell-transfusions-really-worsen-oncologic-outcomes-in-colon-cancer
#6
Ramzi Amri, Anne M Dinaux, Lieve G J Leijssen, Hiroko Kunitake, Liliana G Bordeianou, David L Berger
BACKGROUND: Data from small retrospective studies have argued that perioperative packed red blood cell transfusions may increase the risk of developing metastatic recurrence in cancer patients. This study tests this assumption in a large cohort spanning a decade of operatively treated colon cancer patients. METHODS: All patients undergoing primary resection of a colon cancer at a tertiary care center between 2004-2014 (n = 1,423) were included in a retrospective review of a prospectively maintained data repository...
June 9, 2017: Surgery
https://www.readbyqxmd.com/read/28602496/chylous-leak-after-pancreatic-resection-a%C3%A2-grading-system-was-needed
#7
LETTER
Tarek Debs, Niccolo Petrucciani, Radwan Kassir, Delphine Ouvrier, Anne Claire Frin, Imed Ben Amor, Jean Gugenheim
No abstract text is available yet for this article.
June 8, 2017: Surgery
https://www.readbyqxmd.com/read/28602495/effects-of-socioeconomic-status-on-children-with-well-differentiated-thyroid-cancer
#8
Evan F Garner, Ilan I Maizlin, Matthew B Dellinger, Kenneth W Gow, Melanie Goldfarb, Adam B Goldin, John J Doski, Monica Langer, Jed G Nuchtern, Sanjeev A Vasudevan, Mehul V Raval, Elizabeth A Beierle
BACKGROUND: Well-differentiated thyroid cancer is the most common endocrine malignancy in children. Adult literature has demonstrated socioeconomic disparities in patients undergoing thyroidectomy, but the effects of socioeconomic status on the management of pediatric well-differentiated thyroid cancer remains poorly understood. METHODS: Patients ≤21 years of age with well-differentiated thyroid cancer remains were reviewed from the National Cancer Data Base...
June 8, 2017: Surgery
https://www.readbyqxmd.com/read/28602494/an-enlarged-painful-scrotum
#9
Jeries Paolo Zawaideh, Luca Berardi, Michele Buscaglia, Lorenzo Egildo Derchi
No abstract text is available yet for this article.
June 8, 2017: Surgery
https://www.readbyqxmd.com/read/28602493/alcohol-attenuates-myocardial-ischemic-injury
#10
Laura A Scrimgeour, Brittany A Potz, Nassrene Y Elmadhun, Louis M Chu, Frank W Sellke
BACKGROUND: Moderate alcohol consumption is cardioprotective but the mechanism of action remains unclear. Nuclear factor κ-B regulates the expression of genes involved in inflammation, stress, and apoptosis. We used a swine model of diet-induced metabolic syndrome to investigate the effects of red wine and vodka on nuclear factor κ-B signaling and cytokine activity in chronically ischemic myocardium. METHODS: Yorkshire swine were given a high-fat diet for 4 weeks; an ameroid constrictor was then placed on the left circumflex artery...
June 8, 2017: Surgery
https://www.readbyqxmd.com/read/28602492/open-versus-endovascular-aneurysm-repair-trial-review
#11
Craig Weinkauf, Elizabeth George, Wei Zhou
The Open versus Endovascular Aneurysm Repair trial is the only randomized controlled trial that is funded by the federal government to evaluate the treatment outcomes of infrarenal abdominal aortic aneurysms. Since the initial publication, multiple post-hoc analyses have become available. This review summarizes these data, focusing on the primary outcome measures (ie, overall survival) and several key secondary outcomes including aneurysm-related death, age consideration, secondary procedures, and endoleaks...
June 8, 2017: Surgery
https://www.readbyqxmd.com/read/28599805/re-single-incision-versus-3-port-laparoscopic-cholecystectomy-in-symptomatic-gallstones-a-prospective-randomized-study
#12
LETTER
Ajay Kumar Pal, Deelip Singh, Abhinav Arun Sonkar, Awanish Kumar
No abstract text is available yet for this article.
June 6, 2017: Surgery
https://www.readbyqxmd.com/read/28578142/impact-of-lymph-node-ratio-in-selecting-patients-with-resected-gastric-cancer-for-adjuvant-therapy
#13
Yuhree Kim, Malcolm H Squires, George A Poultsides, Ryan C Fields, Sharon M Weber, Konstantinos I Votanopoulos, David A Kooby, David J Worhunsky, Linda X Jin, William G Hawkins, Alexandra W Acher, Clifford S Cho, Neil Saunders, Edward A Levine, Carl R Schmidt, Shishir K Maithel, Timothy M Pawlik
BACKGROUND: The impact of adjuvant chemotherapy and chemo-radiation therapy in the treatment of resectable gastric cancer remains varied. We sought to define the clinical impact of lymph node ratio on the relative benefit of adjuvant chemotherapy or chemo-radiation therapy among patients having undergone curative-intent resection for gastric cancer. METHODS: Using the multi-institutional US Gastric Cancer Collaborative database, 719 patients with gastric adenocarcinoma who underwent curative-intent resection between 2000 and 2013 were identified...
May 31, 2017: Surgery
https://www.readbyqxmd.com/read/28578141/physiologic-correlates-of-intraoperative-blood-transfusion-among-patients-undergoing-major-gastrointestinal-operations
#14
Marcelo Cerullo, Faiz Gani, Sophia Y Chen, Joseph K Canner, William W Yang, Steven M Frank, Timothy M Pawlik
BACKGROUND: Guidelines for transfusion focus on nadir levels of hemoglobin. Hemoglobin triggers may not be helpful, however, in defining appropriate intraoperative use of packed red blood cells. We sought to define the use of intraoperative packed red blood cells relative to quantitative physiologic factors at the time of operation. METHODS: Prospective intraoperative data on patients undergoing a major gastrointestinal operation between 2010 and 2014 were analyzed...
May 31, 2017: Surgery
https://www.readbyqxmd.com/read/28576385/prognostic-value-of-venous-invasion-in-resected-t3-pancreatic-adenocarcinoma-depth-of-invasion-matters
#15
Pietro Addeo, Michel Velten, Gerlinde Averous, François Faitot, Marlene Nguimpi-Tambou, Gennaro Nappo, Emanuele Felli, Pascal Fuchshuber, Philippe Bachellier
BACKGROUND: Incomplete evaluation of venous invasion has led to conflicting results regarding the prognosis of patients undergoing pancreatectomy with a synchronous venous resection. This study evaluates the prognostic value associated with the presence and the depth of venous invasion in T3 pancreatic adenocarcinoma. METHODS: This study evaluated retrospectively 181 consecutive pancreatoduodenectomies performed for T3N0M0 and T3N1M0 pancreatic adenocarcinomas (stages IIA and IIB) from January 2006 to December 2014...
May 30, 2017: Surgery
https://www.readbyqxmd.com/read/28559084/letter-to-the-editor-regarding-quantitative-study-of-voice-dysfunction-after-thyroidectomy
#16
LETTER
Raouef Ahmed Bichoo, Chandan K Jha, Sanjay K Yadav
No abstract text is available yet for this article.
May 27, 2017: Surgery
https://www.readbyqxmd.com/read/28554491/does-the-emergency-surgery-score-accurately-predict-outcomes-in-emergent-laparotomies
#17
Thomas Peponis, Jordan D Bohnen, Naveen F Sangji, Anirudh R Nandan, Kelsey Han, Jarone Lee, D Dante Yeh, Marc A de Moya, George C Velmahos, David C Chang, Haytham M A Kaafarani
BACKGROUND: The emergency surgery score is a mortality-risk calculator for emergency general operation patients. We sought to examine whether the emergency surgery score predicts 30-day morbidity and mortality in a high-risk group of patients undergoing emergent laparotomy. METHODS: Using the 2011-2012 American College of Surgeons National Surgical Quality Improvement Program database, we identified all patients who underwent emergent laparotomy using (1) the American College of Surgeons National Surgical Quality Improvement Program definition of "emergent," and (2) all Current Procedural Terminology codes denoting a laparotomy, excluding aortic aneurysm rupture...
May 26, 2017: Surgery
https://www.readbyqxmd.com/read/28552169/large-single-center-databases-and-the-evolution-of-endovascular-therapy-for-complex-aortic-aneurysms
#18
Matthew J Eagleton, Behzad Farivar, Agenor Dias
BACKGROUND: Fenestrated and branched endograft repair of complex aortic disease has revolutionized the approach to treatment of this life-threatening problem. Several sites have developed long-standing programs evaluating the application and outcomes of this technology. These reports are based on the development of large, single-center databases. These centers have helped to pioneer the evolution of this approach, and their assessments have led to significant improvements and identified areas that require improvement in the ensuing years...
May 25, 2017: Surgery
https://www.readbyqxmd.com/read/28551380/computed-tomography-measured-psoas-density-predicts-outcomes-in-trauma
#19
Taehwan Yoo, Wilson D Lo, David C Evans
BACKGROUND: Age-related loss of muscle mass and function (sarcopenia) is linked to poor outcomes after operation and trauma. Here we evaluate computed tomography measured psoas muscle density and area using quick and simple tools available to the bedside clinician. We hypothesize these measures will predict poor outcomes after blunt traumatic injury. METHODS: We conducted a retrospective cohort study of patients ages ≥45 years in the Ohio State University Trauma Registry in 2008 that received a computed tomographic scan of the abdomen and/or pelvis with intravenous contrast...
May 24, 2017: Surgery
https://www.readbyqxmd.com/read/28551379/review-of-1-000-consecutive-extracorporeal-membrane-oxygenation-runs-as-a-quality-initiative
#20
Harold N Lovvorn, Daphne C Hardison, Heidi Chen, Ashly C Westrick, Melissa E Danko, Brian C Bridges, William F Walsh, John B Pietsch
BACKGROUND: Extracorporeal membrane oxygenation is a resource-intensive mode of life-support potentially applicable when conventional therapies fail. Given the initial success of extracorporeal membrane oxygenation to support neonates and infants in the 1980s, indications have expanded to include adolescents, adults, and selected moribund patients during cardiopulmonary resuscitation. This single-institution analysis was conducted to evaluate programmatic growth, outcomes, and risk for death despite extracorporeal membrane oxygenation across all ages and diseases...
May 24, 2017: Surgery
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