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Rachel S Bronheim, Eric K Oermann, Samuel K Cho, John M Caridi
STUDY DESIGN: Retrospective cohort study. OBJECTIVE: To identify associations between abnormal coagulation profile and postoperative morbidity and mortality in patients undergoing posterior lumbar fusion (PLF). SUMMARY OF BACKGROUND DATA: The literature suggests that abnormal coagulation profile is associated with postoperative complications, notably the need for blood transfusion. However, there is little research that directly addresses the influence of coagulation profile on postoperative complications following PLF...
October 17, 2016: Spine
Toshinori Sakai, Fumitake Tezuka, Kazuta Yamashita, Yoichiro Takata, Kosaku Higashino, Akihiro Nagamachi, Koichi Sairyo
STUDY DESIGN: A retrospective review of prospectively collected data. OBJECTIVE: To investigate recent outcomes of conservative treatment for bony healing in pediatric patients with lumbar spondylolysis (LS) and to identify the problems that need to be resolved. SUMMARY OF BACKGROUND DATA: Several diagnostic and therapeutic techniques for LS have been developed recently, leading to better outcomes for bony healing. METHODS: Overall, 63 consecutive pediatric patients (53 boys and 10 girls) with LS (average age: 13...
October 17, 2016: Spine
Meagan E Ita, Nathan D Crosby, Ben A Bulka, Beth A Winkelstein
STUDY DESIGN: Immunohistochemistry labeled pre- and post-synaptic structural markers to quantify excitatory and inhibitory synapses in the spinal superficial dorsal horn at 14 days after painful facet joint injury in the rat. OBJECTIVE: The objective of this study was to investigate the relationship between pain and synapse density in the spinal cord after facet injury. SUMMARY OF BACKGROUND DATA: Neck pain is a major contributor to disability and often becomes chronic...
October 17, 2016: Spine
Linlu Zhao, Darren M Roffey, Suzan Chen
STUDY DESIGN: Systematic review and meta-analysis. OBJECTIVE: To assess and synthesize the current evidence on the association between the rs1256120 single nucleotide polymorphism (SNP) of the estrogen receptor beta gene (ESR2) and adolescent idiopathic scoliosis (AIS). SUMMARY OF BACKGROUND DATA: Hormonal disturbance has been postulated as a potential etiological factor in the development of AIS. As estrogen receptors are important mediators of estrogen response, mutations in these genes, including rs1256120 of ESR2, have been chosen as susceptibility candidates for AIS predisposition...
October 17, 2016: Spine
Chang-Hyun Lee, Moon Jun Sohn, Chae Heuck Lee, Chan Young Choi, Seong Rok Han, Byung-Wan Choi
STUDY DESIGN: Systematic review and meta-analysis of studies for the treatment of cervical myelopathy with OPLL treated with laminoplasty or fusion. OBJECTIVE: To delineate whether OPLL continues to progress after laminoplasty compared with fusion and to clarify the relationship between radiological progression of OPLL and neurological decline. SUMMARY OF BACKGROUND DATA: Laminoplasty is usually performed in patients with multilevel ossification of the posterior longitudinal ligament (OPLL) due to the surgical morbidity of anterior surgery...
October 17, 2016: Spine
Ali Nourbakhsh, Fletcher Preuss, Michael Hadeed, Adam Shimer
STUDY DESIGN: Case report. OBJECTIVE: To describe a young adult with a pars defect undergoing percutaneous direct fixation using intraoperative Computed Tomography (CT) scan. SUMMARY OF BACKGROUND DATA: Direct pars repair has been utilized since the 1960 s. There are no reports in the literature describing a percutaneous technique. METHODS: Using a percutaneous technique under the guide of intraoperative CT scan, a cannulated partially threaded screw was inserted across the pars defect...
October 17, 2016: Spine
Louis M Day, Subaraman Ramchandran, Cyrus M Jalai, Bassel G Diebo, Barthelemy Liabaud, Renaud Lafage, Themistocles Protopsaltis, Peter G Passias, Frank J Schwab, Shay Bess, Thomas J Errico, Virginie Lafage, Aaron J Buckland
STUDY DESIGN: Retrospective clinical and radiographic single-center study OBJECTIVE.: Assess simultaneous cervical spine and lower extremity compensatory changes with changes in thoracolumbar spinal alignment. SUMMARY OF BACKGROUND DATA: Full-body stereoradiographic imaging allows better understanding of reciprocal changes in cervical and lower extremity alignment in the setting of thoracolumbar malalignment. Few studies describe the simultaneous effect of alignment correction on these mechanisms...
October 17, 2016: Spine
Malene Rask Andersen, Muhammad Farooq, Karen Koefoed, Klaus W Kjaer, Ane Simony, Sren Tvorup Christensen, Lars Allan Larsen
STUDY DESIGN: Mutation analysis of a candidate disease gene in a cohort of patients with moderate to severe Adolescent idiopathic scoliosis (AIS). OBJECTIVE: To investigate if damaging mutations in the planar cell polarity gene VANGL1 could be identified in AIS patients. SUMMARY OF BACKGROUND DATA: AIS is a spinal deformity which occurs in 1-3% of the population. The cause of AIS is often unknown, but genetic factors are important in the etiology...
October 17, 2016: Spine
Hideaki Kaneko, Shuo Zhang, Miho Sekiguchi, Takuya Nikaido, Koshi Makita, Jiro Kurata, Shin-Ichi Konno
STUDY DESIGN: Cross-sectional study. OBJECTIVE: To evaluate activity of the nucleus accumbens (NAc) in response to lumbar mechanical stimulation in patients with chronic low back pain (cLBP) using functional magnetic resonance imaging (fMRI). SUMMARY OF BACKGROUND DATA: Although a modified activity of the NAc was characterized in cLBP patients, its pathological significance has yet to be determined. We hypothesized that NAc activation in response to pain might differ depending on the extent of psychiatric problems, which might be associated with the affective/motivational background of chronic pain...
October 17, 2016: Spine
Kingsley R Chin, Fabio J R Pencle, Jason A Seale, Franz K Pencle
STUDY DESIGN: A single-center, retrospective study. OBJECTIVE: To determine the safety and outcomes of total disc replacement (TDR) as an outpatient procedure in the ambulatory surgery center (ASC). SUMMARY OF BACKGROUND DATA: Anterior cervical discectomy and fusion (ACDF) has been demonstrated to be safe in the outpatient setting. As the awareness of same day surgery procedures is on the rise due to better outcome and shorter recovery time...
October 17, 2016: Spine
Ming-Xiang Zou, Guo-Hua Lv, Xiao-Bin Wang, Jing Li
No abstract text is available yet for this article.
October 6, 2016: Spine
Anita Mohandas, Chris Summa, W Bradley Worthington, Jason Lerner, Kevin T Foley, Robert J Bohinski, Gregory B Lanford, Carol Holden, Richard N W Wohns
STUDY DESIGN: Delphi Panel expert panel consensus and narrative literature review OBJECTIVE.: To obtain expert consensus on best practices for patient selection and perioperative decision making for outpatient anterior cervical surgery (anterior cervical disc fusion (ACDF) and cervical total disc replacement (CTDR)). SUMMARY OF BACKGROUND DATA: Spine surgery in ambulatory settings is becoming a preferred option for both patients and providers. The transition from traditional inpatient environments has been enabled by innovation in anesthesia protocols and surgical technique, as well as favorable economics...
October 6, 2016: Spine
Rafael De la Garza Ramos, C Rory Goodwin, Taylor Purvis, Isaac O Karikari, Amer F Samdani, Daniel M Sciubba
STUDY DESIGN: Retrospective cohort study of a nationwide database. OBJECTIVE: To compare in-hospital outcomes for pediatric patients who underwent primary versus revision spinal fusion. SUMMARY OF BACKGROUND DATA: There is limited data on outcomes after primary versus revision spinal fusion in children. METHODS: Data from the Nationwide Inpatient Sample from 2002 to 2011 was analyzed. Pediatric patients (age <18) who underwent ≥ 3 level spinal fusion were identified...
October 6, 2016: Spine
Päivi Kolu, Kari Tokola, Markku Kankaanpää, Jaana Suni
STUDY DESIGN: A cross-sectional study, part of a randomized controlled trial. OBJECTIVE: To evaluate the association of physical activity, cardiorespiratory fitness, and neuromuscular fitness with direct health-care costs and sickness-related absence among nursing personnel with nonspecific low back pain. SUMMARY OF BACKGROUND DATA: Low back pain creates a huge economic burden due to increased sick leave and use of health-care services. METHODS: Female nursing personnel with nonspecific low back pain were included (n = 219)...
October 6, 2016: Spine
Harry T Mai, Robert J Burgmeier, Sean M Mitchell, Andrew C Hecht, Joseph C Maroon, Gordon W Nuber, Wellington K Hsu
STUDY DESIGN: Retrospective cohort study OBJECTIVE.: To determine if the level of a cervical disc herniation (CDH) procedure will uniquely impact performance-based outcomes in elite athletes of the National Football League (NFL). SUMMARY OF BACKGROUND DATA: Comparative assessments of post-surgical outcomes in NFL athletes with CDH at different levels are unknown. Further, the surgical decision making for these types of injuries in professional football athletes remains controversial...
September 30, 2016: Spine
D Kojo Hamilton, Christopher Kong, Jayme Hiratzka, Alec G Contag, Tamir Ailon, Breton Line, Alan Daniels, Justin S Smith, Peter Passias, Themistocles Protopsaltis, Daniel Sciubba, Douglas Burton, Christopher Shaffrey, Eric Klineberg, Gregory Mundis, Han-Jo Kim, Virginie Lafage, Renaud Lafage, Justin Scheer, Oheneba Boachie-Adjei, Shay Bess, Robert Hart
STUDY DESIGN: This is a multicenter retrospective review of prospectively collected cases. OBJECTIVE: Our objective was to evaluate the relationship between patient satisfaction, HRQoL scores, complications, and radiographic measures at 2 years post-operative follow-up. SUMMARY OF BACKGROUND DATA: For patients receiving operative management for adult spine deformity (ASD), the relationship between health-related quality of life (HRQoL) measures, radiographic parameters, post-operative complications, and self-reported satisfaction remains unclear...
September 29, 2016: Spine
Rob C Brink, Tom P C Schlösser, Dino Colo, Ludvig Vavruch, Marijn van Stralen, Koen L Vincken, Marcus Malmqvist, Moyo C Kruyt, Hans Tropp, René M Castelein
STUDY DESIGN: Cross-sectional. OBJECTIVE: To investigate the presence and magnitude of anterior spinal overgrowth in neuromuscular scoliosis and compare this to the same measurements in idiopathic scoliosis and healthy spines. SUMMARY OF BACKGROUND DATA: Anterior spinal overgrowth has been described as a potential driver for the onset and progression of adolescent idiopathic scoliosis (AIS). Whether this anterior overgrowth is specific for AIS or also present in non-idiopathic scoliosis has not been reported...
September 28, 2016: Spine
Ross C Puffer, Meghan Murphy, Patrick Maloney, Daryl Kor, Ahmad Nassr, Brett Freedman, Jeremy Fogelson, Mohamad Bydon
STUDY DESIGN: A retrospective review of a consecutive series of spinal fusions comparing patient and procedural characteristics of patients who developed surgical site infections (SSIs) after spinal fusion. OBJECTIVE: It is known that increased surgical time (incision to closure) is associated with a higher rate of postoperative SSIs. We sought to determine whether increased total anesthetic time (intubation to extubation) is a factor in the development of SSIs as well...
September 28, 2016: Spine
Wen-Bin Xu, Jun-Hui Liu, Zhi-Jun Chen, Xiang-Qian Fang, Shun-Wu Fan, Zhi-Jun Hu
STUDY DESIGN: Experimental study evaluated magnetic resonance imaging (MRI) and histologic changes in the multifidus muscle after anterior spinal fusion. OBJECTIVE: To determine the effect of spinal fusion on the multifidus muscle in an anterior rabbit model through the use of MRI and histologic evaluation. SUMMARY OF BACKGROUND DATA: Retraction and splitting approach are known to be important factors in postoperative injury and atrophy of the multifidus muscle...
September 28, 2016: Spine
Morimoto Daijiro, Isu Toyohiko, Kim Kyongsong, Chiba Yasuhiro, Iwamoto Naotaka, Isobe Masanori, Morita Akio
STUDY DESIGN: Prospective observational cohort study. OBJECTIVE: The objective of this study was to present the long-term surgical outcomes of operative treatment for superior cluneal nerve (SCN) entrapment neuropathy (SCNEN) and to analyze the causes of poor results and further treatment required. SUMMARY OF BACKGROUND DATA: There are few reports of the outcomes of surgical treatment for SCNEN, and most studies describe results for operations conducted under general anesthesia with short follow-up periods...
September 23, 2016: Spine
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