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Sleep Medicine

Daniel Ruivo Marques, Vanda Clemente, Ana Allen Gomes, Maria Helena Pinto de Azevedo
No abstract text is available yet for this article.
January 4, 2018: Sleep Medicine
Alexander Neergaard Olesen, Matteo Cesari, Julie Anja Engelhard Christensen, Helge Bjarup Dissing Sorensen, Emmanuel Mignot, Poul Jennum
OBJECTIVE: To evaluate rapid eye movement (REM) muscular activity in narcolepsy by applying five algorithms to electromyogram (EMG) recordings, and to investigate its value for narcolepsy diagnosis. PATIENTS/METHODS: A modified version of phasic EMG metric (mPEM), muscle activity index (MAI), REM atonia index (RAI), supra-threshold REM EMG activity metric (STREAM), and Frandsen method (FR) were calculated from polysomnography recordings of 20 healthy controls, 18 clinic controls (subjects suspected with narcolepsy but finally diagnosed without any sleep abnormality), 16 narcolepsy type one without REM sleep behavior disorder (RBD), nine narcolepsy type one with RBD, and 18 narcolepsy type two...
April 2018: Sleep Medicine
Victoria M Pak, Feng Dai, Brendan T Keenan, Nalaka S Gooneratne, Allan I Pack
Sleepiness and cardiovascular disease share common molecular pathways; thus, metabolic risk factors for sleepiness may also predict cardiovascular disease risk. Daytime sleepiness predicts mortality and cardiovascular disease, although the mechanism is unidentified. This study explored the associations between subjective sleepiness and metabolite concentrations in human blood plasma within the oxidative and inflammatory pathways, in order to identify mechanisms that may contribute to sleepiness and cardiovascular disease risk...
April 2018: Sleep Medicine
Ezra M Cohen, Michelle L Dossett, Darshan H Mehta, Roger B Davis, Yvonne C Lee
OBJECTIVES: Sleep difficulties are a serious health problem in children, and interest in using complementary and alternative medicine (CAM) therapies to treat sleep is growing. In this study, we aimed to identify: the prevalence of sleep difficulties in children, and the prevalence and patterns of CAM use among children with trouble sleeping. METHODS: We used the 2012 National Health Interview Survey (NHIS) dataset to estimate the prevalence of sleep difficulties and CAM use in children ages 6-17 years...
April 2018: Sleep Medicine
Takafumi Monma, Akira Ando, Tohru Asanuma, Yutaka Yoshitake, Goichiro Yoshida, Taiki Miyazawa, Naoyuki Ebine, Satoko Takeda, Naomi Omi, Makoto Satoh, Kumpei Tokuyama, Fumi Takeda
OBJECTIVE: To clarify sleep disorder risk factors among student athletes, this study examined the relationship between lifestyle habits, competition activities, psychological distress, and sleep disorders. METHODS: Student athletes (N = 906; male: 70.1%; average age: 19.1 ± 0.8 years) in five university sports departments from four Japanese regions were targeted for analysis. Survey items were attributes (age, gender, and body mass index), sleep disorders (recorded through the Pittsburgh Sleep Quality Index), lifestyle habits (bedtime, wake-up time, smoking, drinking alcohol, meals, part-time jobs, and use of electronics after lights out), competition activities (activity contents and competition stressors), and psychological distress (recorded through the K6 scale)...
April 2018: Sleep Medicine
Yiping Chen, Christiana Kartsonaki, Robert Clarke, Yu Guo, Canqing Yu, Zheng Bian, Qilian Jiang, Shanpeng Li, Junshi Chen, Liming Li, Zhengming Chen
BACKGROUND: Inadequate sleep duration and insomnia can affect both physical and mental health. There is limited evidence, however, on characteristics and correlates of sleep patterns and insomnia in urban and rural China. METHODS: This cross-sectional study, involving 512,891 adults aged 30-79 years from ten (five urban and five rural) diverse areas in China, recorded detailed information, using interviewer-administered laptop-based questionnaires, on sleep patterns (duration, daytime napping and snoring) and insomnia symptoms...
April 2018: Sleep Medicine
Cynthia R Johnson, Tristram Smith, Alexandra DeMand, Luc Lecavalier, Victoria Evans, Matthew Gurka, Naomi Swiezy, Karen Bearss, Lawrence Scahill
BACKGROUND AND PURPOSE: Sleep disturbances in autism spectrum disorder (ASD) are common and may impair daytime functioning as well as add to parental burden. In this well characterized sample of young children with ASD and disruptive behaviors, we examine the association of age and IQ in sleep disturbances using the Child Sleep Habits Questionnaire modified for ASD (CSHQ-ASD). We also test whether children with poor sleep have greater daytime behavioral problems than those with better sleep...
April 2018: Sleep Medicine
Monica Moresco, Mariangela Lecciso, Darina Ocadlikova, Marco Filardi, Silvia Melzi, Birgitte Rahbek Kornum, Elena Antelmi, Fabio Pizza, Emmanuel Mignot, Antonio Curti, Giuseppe Plazzi
BACKGROUND: Type 1 narcolepsy (NT1) is a central hypersomnia linked to the destruction of hypocretin-producing neurons. A great body of genetic and epidemiological data points to likely autoimmune disease aetiology. Recent reports have characterized peripheral blood T-cell subsets in NT1, whereas data regarding the cerebrospinal fluid (CSF) immune cell composition are lacking. The current study aimed to characterize the T-cell and natural killer (NK) cell subsets in NT1 patients with long disease course...
April 2018: Sleep Medicine
Juhyeun Kim, Abraham G Hartzema
STUDY OBJECTIVES: The objective of this study is to assess adherence and persistence of ropinirole, pramipexole, and gabapentin; to investigate factors associated with non-adherence and non-persistence in restless legs syndrome (RLS) patients. METHODS: We used the 2008-2014 Marketscan® Research Databases to conduct a retrospective data analysis. The study included newly diagnosed RLS patients who initiated ropinirole, pramipexole, or gabapentin therapy. During 365 days of follow-up, mean medication possession ratios (MPRs) for adherence and the proportion of adherent users were calculated...
April 2018: Sleep Medicine
Shinya Makino, Sachie Hirose, Miki Kakutani, Masayoshi Fujiwara, Mitsuru Nishiyama, Yoshio Terada, Hitoshi Ninomiya
OBJECTIVES: To clarify the relationship between nighttime sleep duration, midday naps, and glycemic control in Japanese patients diagnosed with type 2 diabetes (n = 355) or impaired glucose tolerance (n = 43). METHODS: A total of 398 patients completed a self-administered questionnaire on sleep duration/quality and were divided into five groups according to their self-reported nighttime sleep duration: <5 h, 5-6 h, 6-7 h, 7-8 h, and >8 h. Each group was further divided into two subgroups each according to the presence or absence of midday naps...
April 2018: Sleep Medicine
Yi-Qi Lin, Sheng-Di Chen
Increasing evidence indicates a strong association between rapid eye movement sleep behavior disorder (RBD) and Parkinson's disease - cognitive impairment (PD-CI). Numerous longitudinal and cross-sectional studies have shown that RBD may be an important risk factor and predictor of Parkinson's disease - mild cognitive impairment (PD-MCI) and Parkinson's disease dementia (PDD); which may be explained by the association of mechanisms between RBD and PD-CI, including neurotransmitter alterations, genetic mutation, neuroinflammation, alpha-synuclein inclusion, abnormal cerebral metabolism and cortical activity slowing...
April 2018: Sleep Medicine
Rachel P Ogilvie, Kamakshi Lakshminarayan, Conrad Iber, Sanjay R Patel, Pamela L Lutsey
BACKGROUND: Although excessive daytime sleepiness (EDS) is a common symptom of obstructive sleep apnea (OSA), and both EDS and OSA have separately been associated with increased risk of cardiovascular disease (CVD), their joint association with CVD risk is unknown. METHODS: Among 3874 Sleep Heart Health Study (SHHS) participants without prevalent CVD, moderate to severe OSA was defined by an apnea hypopnea index (AHI) ≥ 15 on an in-home polysomnography. EDS was defined as an Epworth Sleepiness Scale score ≥11...
April 2018: Sleep Medicine
Jessica K Martino, Christopher B Freelance, Gregory L Willis
Insomnia, hypersomnia and REM Sleep Behavior Disorder (RSBD) during sleep are major problems for patients suffering from Parkinson's disease (PD) but they are also used to predict its onset. While these secondary symptoms detract from the quality of life in PD patients, few treatment options are available due to limited efficacy or risk of complicating the treatment regimen. Light therapy (LT) has been suggested as a strategy for sleep disorders but it has only been implemented recently for use in PD. An open label, retrospective study was undertaken where PD patients had been undergoing LT, using polychromatic light, for four months to 15 years prior...
April 2018: Sleep Medicine
Ruth L F Leong, Shirley Y J Koh, Jesisca Tandi, Michael W L Chee, June C Lo
Prospective memory is defined as remembering to do something at a particular moment in the future and may be modulated by sleep. Here, we investigated whether multiple nights of partial sleep deprivation would affect the successful retrieval of intentions. Fifty-nine adolescents (mean age ± SD: 16.1 ± 0.6 years) were instructed to remember to press specific keys in response to the target words presented during a semantic categorization task in the future. Their memory was tested after five nights of either 5-h (sleep restriction group) or 9-h time-in-bed (control group)...
April 2018: Sleep Medicine
Akiyoshi Shimura, Sakai Hideo, Yoshikazu Takaesu, Ryota Nomura, Yoko Komada, Takeshi Inoue
OBJECTIVE: Sleep affects adolescents in various ways. However, the effects of multiple factors on sleep hygiene remain unclear. A comprehensive assessment of the effects of life habits on sleep in high-school students was conducted. METHODS: A cross-sectional survey of 344 high school students (age range 15-17; 171 boys, 173 girls) in Tokyo, Japan was conducted in 2015. Complete responses were provided by 294 students. Demographic variables, Pittsburgh Sleep Quality Index (PSQI), diurnal type scale, Pediatric Daytime Sleepiness Scale (PDSS), and life habits such as dinnertime, viewing electronic displays, caffeine intake, sunlight in the morning, and the brightness of the room in the night were asked...
April 2018: Sleep Medicine
C Overbergh, S Installe, A Boudewyns, K Van Hoorenbeeck, S L Verhulst
Continuous positive airway pressure (CPAP) is being increasingly used in children of all age ranges. The limited number of commercially available masks especially in infants and young children may complicate its use and compliance. In this report, we describe our experience with the use of the Optiflow™ (Fisher and Paykel Healthcare) Nasal Cannula attached to a regular CPAP device in the setting of chronic CPAP use. This interface consists of a nasal cannula and was originally designed for the delivery of high-flow oxygen therapy...
April 2018: Sleep Medicine
Denise Manica, Cláudia Schweiger, Leo Sekine, Simone Chaves Fagondes, Gabriel Kuhl, Marcus Vinicius Collares, Paulo José Cauduro Marostica
OBJECTIVES: To evaluate the association of polysomnographic parameters with clinical symptom severity in Robin sequence (RS) patients. METHODS: All patients diagnosed as presenting with RS at Hospital de Clínicas de Porto Alegre from October 2012 to June 2016 were enrolled. They were classified as isolated RS, RS-plus, and syndromic RS. Polysomnography (PSG) was performed, except for those patients in need of respiratory support. Symptom severity was evaluated as defined by the Cole et al...
March 2018: Sleep Medicine
Eve Reynaud, Anne Forhan, Barbara Heude, Marie-Aline Charles, Sabine Plancoulaine
OBJECTIVE: The aim was to study, with a developmental approach, the longitudinal association between night-waking from age 2 to 5-6 years and behavior at age 5-6 years. METHODS: Within the French birth cohort study Etude sur les Déterminants pré et post natals du développement et de la santé de l'ENfant (EDEN), repeated measures of children's night-waking were collected at age 2, 3 and 5-6 through parental questionnaires and were used to model night-waking trajectories...
March 2018: Sleep Medicine
Winda L Ng, Jonathan E Shaw, Anna Peeters
OBJECTIVE: To assess the relationship between excessive daytime sleepiness (EDS), disability, mortality, and life expectancy (with and without disability) in a cohort of middle-aged American adults. METHODS: The Wisconsin Longitudinal Study, a life-course study on 10,317 high school graduates from Wisconsin, was used to assess the odds ratio (OR) between EDS in 2004 for prevalent and incident disability to 2011 through multiple logistic regression, and to estimate the hazard ratio (HR) of EDS in 2004 for mortality over ten years through a Cox proportional hazard model...
March 2018: Sleep Medicine
Bat Sheva Goldberger-Raskin, Doron Gothelf, Rachel Bachner-Melman, Claudia Lang, Jonathan Kushnir
OBJECTIVE: Previous research has demonstrated a link between childhood anxiety and sleep problems, but little is known about the link between these difficulties and parental sleep disturbances. The purpose of the current study was to explore the association between anxious children's sleep difficulties and those of their mothers. METHOD: A total of 101 children aged 8-18 years and their mothers participated in this study. The clinical group included 66 children (mean age = 11...
March 2018: Sleep Medicine
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