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Sleep Medicine

Mohammad Rasoul Ghadami
No abstract text is available yet for this article.
August 23, 2018: Sleep Medicine
Duygu Duran Orlowski, Levent Öztürk
No abstract text is available yet for this article.
August 18, 2018: Sleep Medicine
Fanyi Kong, Guoyi Liu, Jingjing Xu
Several hypnotic agents commonly recommended for improving sleep at sea level are discouraged at high altitude. We aimed to evaluate the efficacy and safety of drugs prescribed for improving sleep quality in patients with acute exposure to high altitudes by conducting a systematic review and meta-analysis. An electronic search was executed for randomized controlled trials comparing drug treatments with placebo and no-treatment conditions, which used objective sleep parameters or subjective sleep quality evaluations...
August 16, 2018: Sleep Medicine
Ana Fernández-Arcos, Isabel Vilaseca, Iban Aldecoa, Mónica Serradell, Eduard Tolosa, Joan Santamaría, Ellen Gelpi, Alex Iranzo
BACKGROUND: The neuropathological hallmark of Parkinson's disease (PD) is the presence of aggregates of phosphorylated alpha-synuclein (pAS) in the nervous system. METHOD: We report a patient with video-polysomnography-confirmed idiopathic REM sleep behavior disorder that underwent parotidectomy because of parotid gland cancer. Immunohistochemistry of the gland tissue revealed abundant pAS deposits. One year after surgery the patient was diagnosed with PD. Prompted by this observation we examined the parotid gland in 10 consecutive individuals that underwent elective parotidectomy irrespective of their clinical condition...
August 14, 2018: Sleep Medicine
Ilaria Bartolini, Fabio Pizza, Andrea Di Luzio, Giulia Neccia, Elena Antelmi, Stefano Vandi, Giuseppe Plazzi
OBJECTIVE: Although being the most specific symptom of narcolepsy type 1 (NT1), cataplexy is currently investigated by clinical interview only, with potential diagnostic pitfalls. Our study aimed at testing the accuracy of an automatic video detection of cataplexy in NT1 patients vs. non-cataplectic subjects undergoing a standardized test with emotional stimulation. METHODS: Fifteen drug-naive NT1 patients and 15 age- and sex-balanced non-cataplectic subjects underwent a standardized video recording procedure including emotional stimulation causing laughter...
August 10, 2018: Sleep Medicine
Shihoko Koyama, Jun Aida, Noriko Cable, Toru Tsuboya, Yusuke Matsuyama, Yukihiro Sato, Tatsuo Yamamoto, Katsunori Kondo, Ken Osaka
BACKGROUND: No studies have examined the associations between the numbers of teeth and sleep disturbance. Therefore, we examined the associations between the number of teeth and sleep duration in older people, considering the evidence linking fewer teeth and sleep apnoea through changes in jaw position. METHODS: For this study we used information from a sample of 23,444 cohort participants, randomly selected from the Japan Gerontological Evaluation Study 2010 (N = 169,215)...
August 10, 2018: Sleep Medicine
Iva Prihodova, Iva Dudova, Marketa Mohaplova, Michal Hrdlicka, Sona Nevsimalova
BACKGROUND: Childhood narcolepsy is associated with various emotional, behavioural and cognitive dysfunctions as well as with psychiatric and neurodevelopmental disorders: anxiety, depression, attention deficit hyperactivity disorder and psychosis. A relationship between these conditions is unclear - comorbidity or similar pathophysiological mechanisms can be suggested. OBJECTIVE: We reported four children with narcolepsy type 1 (NT1) and autism spectrum disorder (ASD) - Asperger syndrome (AS)...
August 9, 2018: Sleep Medicine
Kamila Weissová, Jitka Škrabalová, Kateřina Skálová, Kateřina Červená, Zdeňka Bendová, Eva Miletínová, Jana Kopřivová, Karel Šonka, Daniela Dudysová, Aleš Bartoš, Jitka Bušková
OBJECTIVE: To evaluate changes in the expression of clock genes and melatonin levels in patients with idiopathic REM sleep behavior disorder (RBD) as a potential early stage of synucleinopathies. METHODS: We assessed the rhythmicity of circadian clock genes using real time-quantitative polymerase chain reaction and 24-h blood melatonin profiles using radio-immunoassay in 10 RBD patients and nine age-matched controls. RESULTS: The RBD patients did not show circadian rhythmicity for clock genes Per2, Bmal1, and Nr1d1 but the rhythmicity of Per 1 remained, and the amplitude of Per3 was diminished...
August 9, 2018: Sleep Medicine
Torbjörn Åkerstedt, Johanna Schwarz, Georg Gruber, Jenny Theorell-Haglöw, Eva Lindberg
OBJECTIVE: Combined insomnia and obstructive sleep apnea has been the focus of considerable research with respect to its health effects. A related issue is whether sleep disturbances in combination with snoring might exert effects on objective sleep variables in the non-clinical general population. The purpose of the present study was to investigate the polysomnographical characteristics of individuals who had sought medical help for both disturbed sleep and for snoring. No previous work of this type has been carried out...
August 9, 2018: Sleep Medicine
Xiu Hong Yang, Bao Long Zhang, Yan Hong Gu, Xiao Li Zhan, Li Li Guo, Hui Min Jin
OBJECTIVE: Sleep disorders, chronic pain, and fatigue have been long-standing torments in most patients with chronic kidney disease (CKD). In this review, we attempted to explore whether these nontraditional cardiovascular risk factors are associated with increased mortality in patients with CKD. METHOD: Electronic searches were performed in MEDLINE (PubMed, 1966-2018), EMBASE (1974-2018),, and the Cochrane Central Register of Controlled Trials databases...
August 9, 2018: Sleep Medicine
Claudia Picard-Deland, Michelle Carr, Tyna Paquette, Tore Nielsen
Nightmares are a common sleep disorder, defined as highly disturbing mentation which usually awakens the individual from rapid eye movement (REM) sleep. While nightmares are mainly a REM sleep phenomenon, Picard-Deland et al., (2017) recently showed an association between nightmare recall and sleep spindles, which are a non-rapid eye movement (NREM) oscillatory feature. Their results pointed to fewer slow spindles and a higher oscillatory frequency for fast spindles among frequent nightmare recallers compared with controls...
August 8, 2018: Sleep Medicine
Jon Genuneit, Pablo E Brockmann, Angelika A Schlarb, Dietrich Rothenbacher
No abstract text is available yet for this article.
August 7, 2018: Sleep Medicine
Guihua Hao, Wei Lu, Jie Huang, Wei Ding, Pengfei Wang, Lili Wang, Feng Ding, Min Hu, Lili Hou
OBJECTIVE: Hemodialysis (HD) patients are exposed to dysregulated fluid balance which can lead to overhydration. Poor sleep quality and excessive daytime sleepiness are particularly common in these patients, however the relationship between fluid status and sleep quality and daytime sleepiness has not yet been studied. Therefore, the aim of this study is to evaluate the correlations between fluid status and sleep quality and daytime sleepiness in HD patients. METHOD: This cross-sectional study included 115 HD patients and 30 healthy control subjects from the HD center of Shanghai Ninth People's Hospital...
July 31, 2018: Sleep Medicine
Stephen P Becker, Jessica A Lienesch
OBJECTIVE: This study examined nighttime media use in relation to sleep problems and anxiety/depression symptoms in adolescents with attention-deficit/hyperactivity disorder (ADHD). METHODS: Participants were 81 adolescents (69% male) ages 13-17 with ADHD. Adolescents completed measures assessing pubertal development, nighttime media use, circadian preference, and daytime sleepiness. Both adolescents and parents completed measures of sleep duration, sleep problems, and internalizing symptoms...
July 29, 2018: Sleep Medicine
Zhengyan Shen, Ning Zhou, Ligeng Wu
OBJECTIVES: The aim of this cross-sectional study was to assess the psychological status of patients with bruxism and to explore the potential relationship between psychological status and rhythmic masticatory muscle activity (RMMA), since the basic manifestation of sleep bruxism is RMMA. METHODS: Twenty-five patients (nine males, 16 females, and mean age 27.84 ± 5.60) who self-reported having SB and 25 normal subjects were randomly recruited. Fifty subjects filled out the Symptom Checklist-90 (SCL-90) to assess their psychopathological status...
July 19, 2018: Sleep Medicine
Victoria Dreier Thøfner Hultén, Fin Biering-Sørensen, Niklas Rye Jørgensen, Poul Jørgen Jennum
STUDY OBJECTIVES: The aim of this study was to investigate circadian rhythm and sleep complaints in individuals with spinal cord injury (SCI) as determined by diurnal saliva melatonin and cortisol as well as activity measurements and subjective sleep quality. METHODS: Fourteen patients with cervical SCI (cSCI), six patients with thoracic SCI (tSCI) and eight able-bodied controls all underwent two consecutive weeks wearing a wrist actigraph in addition to filling out a sleep diary...
July 19, 2018: Sleep Medicine
Bankim Shah, Sushanth Bhat, Peter Polos, Divya Gupta, Sudhansu Chokroverty
No abstract text is available yet for this article.
July 17, 2018: Sleep Medicine
Andreas Palm, Bengt Midgren, Jenny Theorell-Haglöw, Magnus Ekström, Mirjam Ljunggren, Christer Janson, Eva Lindberg
OBJECTIVES: Adherence to continuous positive airway pressure (CPAP) in patients with obstructive sleep apnea (OSA) is crucial. Our aim was to identify protective and risk factors against the discontinuation of CPAP treatment in patients with OSA and to estimate the mortality risk in those who were non-adherent to CPAP therapy. METHODS: This was a registry-based cohort study from 37 centers across Sweden with OSA patients on CPAP in the Swedevox Swedish national registry between July 2010 and March 2017...
July 17, 2018: Sleep Medicine
Zobida Islam, Shamima Akter, Takeshi Kochi, Huanhuan Hu, Masafumi Eguchi, Miwa Yamaguchi, Keisuke Kuwahara, Isamu Kabe, Tetsuya Mizoue
OBJECTIVE: Social jetlag, ie, the mismatch between biological and social timing, has been suggested to induce obesity and cardiometabolic abnormalities. Yet, no study has currently linked social jetlag to metabolic syndrome (MetS) among Asians. The aim of this study was to investigate the cross-sectional association of social jetlag with MetS in a Japanese working population. METHODS: Participants were 1164 employees, aged 18-78 years, who completed a health survey at a periodic checkup...
July 12, 2018: Sleep Medicine
Min Kyoung Kang, Dae Lim Koo, Jung Hwan Shin, Hyung-Min Kwon, Hyunwoo Nam
OBJECTIVE: Periodic limb movements (PLMs) can increase the risk of cardiovascular disease and mortality. Small vessel disease (SVD) has been considered a precursor to symptomatic stroke. We aimed to investigate the association between PLMs and cerebral SVD. METHODS: We enrolled participants who visited our clinic for the evaluation of sleep disturbance and underwent overnight polysomnography and brain magnetic resonance imaging. The processing steps included rating and analyzing white matter hyperintensities (WMHs), cerebral microbleeds (CMBs), asymptomatic lacunar infarctions (ALIs), perivascular spaces (PVSs), and calculating the total SVD score...
July 11, 2018: Sleep Medicine
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