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Seminars in Nuclear Medicine

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https://www.readbyqxmd.com/read/30193652/spect-ct-in-postoperative-shoulder-pain
#1
REVIEW
Mathilde Thélu-Vanysacker, Paycha Frédéric, Thélu Charles-Edouard, Bailliez Alban, Bonnevialle Nicolas, Blaire Tanguy
Over the last 2 decades, the incidence of prosthetic shoulder replacements has increased considerably, leading to a rising number of complications and reoperations. In this article, we review how SPECT/CT can be of significant clinical value for shoulder surgeons. Bone SPECT/CT can provide the correct diagnosis for different types of mechanical complications: glenoiditis after hemiarthroplasty, glenoidal loosening after total shoulder arthroplasty, and scapular notching after reverse shoulder arthroplasty. Various nuclear medicine methods are available for detecting prosthesis infection...
September 2018: Seminars in Nuclear Medicine
https://www.readbyqxmd.com/read/30193651/spect-ct-in-postoperative-foot-and-ankle-pain
#2
REVIEW
Willm Uwe Kampen, Florian Westphal, Tim Van den Wyngaert, Klaus Strobel, Torsten Kuwert, Wouter Van der Bruggen, Gopinath Gnanasegaran, Jan-Hauke Jens, Frédéric Paycha
Postoperative pain is a clinically relevant issue in orthopedic patients, affecting more than 40% 1 year after foot and ankle surgery. Because of the very complex anatomy with many different joints and several motion axes, clinical examination and conventional imaging are sometimes not sufficient to identify a local pain generator. Local uptake of bone-seeking radiopharmaceuticals is known to correlate accurately with sites of pain generating foci and, thus, bone scintigraphy has been an established method to evaluate these respective patients for many years...
September 2018: Seminars in Nuclear Medicine
https://www.readbyqxmd.com/read/30193650/spect-ct-in-the-postoperative-painful-knee
#3
REVIEW
Wouter van der Bruggen, Michael T Hirschmann, Klaus Strobel, Willm Uwe Kampen, Torsten Kuwert, Gopinath Gnanasegaran, Tim Van den Wyngaert, Frédéric Paycha
This review summarizes the role of SPECT/CT in patients with a painful postoperative knee and describes typical diagnostic criteria in these patients. Pain after knee surgery is common and is influenced by the underlying pathology, the type of surgery, and the patient. Knee joint-preserving surgery includes osteotomy, ligament reconstruction, meniscus surgery, and cartilage repair procedures, often used in combination. Knee arthroplasty procedures consist of unicondylar, patellofemoral, and primary or revision total knee prosthesis...
September 2018: Seminars in Nuclear Medicine
https://www.readbyqxmd.com/read/30193649/spect-ct-in-postoperative-painful-hip-arthroplasty
#4
REVIEW
Tim Van den Wyngaert, Frédéric Paycha, Klaus Strobel, Willm Uwe Kampen, Torsten Kuwert, Wouter van der Bruggen, Gopinath Gnanasegaran
Consecutive milestones in hip arthroplasty design and surgical technique have contributed to the successful and cost-effective intervention this procedure has become today in maintaining mobility and quality of life in patients with osteoarthritis, fracture, or other hip conditions. With the increasing prevalence of hip joint replacements, the need for improved diagnostic imaging tools to guide revision surgery has risen in parallel. Over the last few years, promising data have emerged on the potential role of bone SPECT/CT imaging in the assessment of patients with recurrent pain after arthroplasty...
September 2018: Seminars in Nuclear Medicine
https://www.readbyqxmd.com/read/30193648/bone-spect-ct-in-postoperative-spine
#5
REVIEW
Gopinath Gnanasegaran, Frédéric Paycha, Klaus Strobel, Wouter van der Bruggen, Willm Uwe Kampen, Torsten Kuwert, Tim Van den Wyngaert
Back pain is a common problem and the diagnosis and treatment depend on the clinical presentation, yet overlap between pain syndromes is common. Imaging of patients with chronic back pain in both pre- and postoperative scenarios include radiological, radionuclide, and hybrid techniques. In general, these techniques have their own advantages and limitations. The aim of surgery is to eliminate pathologic segmental motion and accompanying symptoms, especially pain. However, surgical procedures are not without complications and localizing the cause of the pain is often challenging...
September 2018: Seminars in Nuclear Medicine
https://www.readbyqxmd.com/read/30193647/spect-ct-in-postoperative-hand-and-wrist-pain
#6
REVIEW
Klaus Strobel, Wouter van der Bruggen, Urs Hug, Gopinath Gnanasegaran, Willm Uwe Kampen, Torsten Kuwert, Frédéric Paycha, Tim van den Wyngaert
In this review we summarize the current evidence and experience regarding the performance of SPECT/CT in the evaluation of patients with postoperative painful wrist or hand. There is a wide range of operative wrist and hand interventions due to congenital, traumatic, degenerative, or inflammatory diseases. A significant number of patients suffer from pain after operative procedures. Several imaging modalities have been used to evaluate the reason for painful postoperative wrists like standard conventional x-rays, ultrasound, CT, MRI, or bone scintigraphy...
September 2018: Seminars in Nuclear Medicine
https://www.readbyqxmd.com/read/30193646/letter-from-the-guest-editors
#7
EDITORIAL
Frederic Paycha, Gopinath Gnanasegaran, Tim Van den Wyngaert
No abstract text is available yet for this article.
September 2018: Seminars in Nuclear Medicine
https://www.readbyqxmd.com/read/30193645/letter-from-the-editors
#8
EDITORIAL
Leonard M Freeman, M Donald Blaufox
No abstract text is available yet for this article.
September 2018: Seminars in Nuclear Medicine
https://www.readbyqxmd.com/read/29852947/snmmi-procedure-standard-eanm-practice-guideline-for-diuretic-renal-scintigraphy-in-adults-with-suspected-upper-urinary-tract-obstruction-1-0
#9
REVIEW
Andrew T Taylor, David C Brandon, Diego de Palma, M Donald Blaufox, Emmanuel Durand, Belkis Erbas, Sandra F Grant, Andrew J W Hilson, Anni Morsing
No abstract text is available yet for this article.
July 2018: Seminars in Nuclear Medicine
https://www.readbyqxmd.com/read/29852946/radiation-imagers-for-quantitative-single-particle-digital-autoradiography-of-alpha-and-beta-particle-emitters
#10
REVIEW
Brian W Miller
Promising therapies are being developed or are in early-stage clinical trials that employ the use of alpha- and beta-emitting radionuclides to cure hematologic malignancies. However, these targeted radionuclide therapies have not yet met their expected potential for cancer treatment. A primary reason is lack of biodistribution, dosimetry, and dose-response information at cellular levels, which are directly related to optimal targeting, achieving a requisite therapeutic dose, and assessing the safety profile in normal organs and tissues...
July 2018: Seminars in Nuclear Medicine
https://www.readbyqxmd.com/read/29852945/innovations-in-nuclear-imaging-instrumentation-cerenkov-imaging
#11
REVIEW
Ryo Tamura, Edwin C Pratt, Jan Grimm
Cerenkov luminescence (CL) is blue glow light produced by charged subatomic particles travelling faster than the phase velocity of light in a dielectric medium such as water or tissue. CL was first discovered in 1934, but for biomedical research it was recognized only in 2009 after advances in optical camera sensors brought the required high sensitivity. Recently, applications of CL from clinical radionuclides have been rapidly expanding to include not only preclinical and clinical biomedical imaging but also an approach to therapy...
July 2018: Seminars in Nuclear Medicine
https://www.readbyqxmd.com/read/29852944/absolute-quantitation-of-spect-studies
#12
REVIEW
Michael Ljungberg
Methods for absolute quantitation of SPECT images provide an estimate of the activity uptakes in various organs and tissues in units of (M)Bq or (m)Ci. However, because tomographic SPECT images generally are hampered by several physical and camera-specific effects, accurate and precise compensation methods are required. The most important effects are (1) photon attenuation in the patient resulting in a reduction of expected acquired count; (2) the contribution of events from photons, scattered in the phantom and the collimator but accepted by the energy window because of a poor energy resolution of the NaI(Tl) crystal; and (3) the effect of the collimator response function that degrades the image quality because of the relatively poor spatial resolution...
July 2018: Seminars in Nuclear Medicine
https://www.readbyqxmd.com/read/29852943/pet-mri-hybrid-systems
#13
REVIEW
Julia G Mannheim, Andreas M Schmid, Johannes Schwenck, Prateek Katiyar, Kristina Herfert, Bernd J Pichler, Jonathan A Disselhorst
Over the last decade, the combination of PET and MRI in one system has proven to be highly successful in basic preclinical research, as well as in clinical research. Nowadays, PET/MRI systems are well established in preclinical imaging and are progressing into clinical applications to provide further insights into specific diseases, therapeutic assessments, and biological pathways. Certain challenges in terms of hardware had to be resolved concurrently with the development of new techniques to be able to reach the full potential of both combined techniques...
July 2018: Seminars in Nuclear Medicine
https://www.readbyqxmd.com/read/29852942/innovations-in-instrumentation-for-positron-emission-tomography
#14
REVIEW
Eric Berg, Simon R Cherry
PET scanners are sophisticated and highly sensitive biomedical imaging devices that can produce highly quantitative images showing the 3-dimensional distribution of radiotracers inside the body. PET scanners are commonly integrated with x-ray CT or MRI scanners in hybrid devices that can provide both molecular imaging (PET) and anatomical imaging (CT or MRI). Despite decades of development, significant opportunities still exist to make major improvements in the performance of PET systems for a variety of clinical and research tasks...
July 2018: Seminars in Nuclear Medicine
https://www.readbyqxmd.com/read/29852941/guest-editorial
#15
EDITORIAL
Pat Zanzonico
No abstract text is available yet for this article.
July 2018: Seminars in Nuclear Medicine
https://www.readbyqxmd.com/read/29852940/editorial-innovations-in-nuclear-medicine-instrumentation
#16
EDITORIAL
Leonard M Freeman, M Donald Blaufox
No abstract text is available yet for this article.
July 2018: Seminars in Nuclear Medicine
https://www.readbyqxmd.com/read/29626946/implementation-of-quality-systems-in-nuclear-medicine-why-it-matters-an-outcome-analysis-quality-management-audits-in-nuclear-medicine-part-iii
#17
REVIEW
Maurizio Dondi, Diana Paez, Leonel Torres, Mario Marengo, Angelika Bischof Delaloye, Kishor Solanki, Annare Van Zyl Ellmann, Enrique Estrada Lobato, Rodolfo Nunez Miller, Francesco Giammarile, Thomas Pascual
The International Atomic Energy Agency (IAEA) developed a comprehensive program-Quality Management Audits in Nuclear Medicine (QUANUM). This program covers all aspects of nuclear medicine practices including, but not limited to, clinical practice, management, operations, and services. The QUANUM program, which includes quality standards detailed in relevant checklists, aims at introducing a culture of comprehensive quality audit processes that are patient oriented, systematic, and outcome based. This paper will focus on the impact of the implementation of QUANUM on daily routine practices in audited centers...
May 2018: Seminars in Nuclear Medicine
https://www.readbyqxmd.com/read/29626945/molecular-imaging-of-vulnerable-plaque
#18
REVIEW
Takehiro Nakahara, Jagat Narula, H William Strauss
Molecular imaging provides multiple imaging techniques to identify characteristics of vulnerable plaque including I) Inflammatory cells (the presence and metabolic activity of macrophages), II) synthesis of lipid and fatty acid in the plaque, III) the presence of hypoxia in severely inflamed lesions, IV) expression of factors stimulating angiogenesis, V) expression of protease enzymes in the lesion, VI) development of microthrombi in late-phase lesions, VII) apoptosis, and VIII) microcalcification.
May 2018: Seminars in Nuclear Medicine
https://www.readbyqxmd.com/read/29626944/molecular-imaging-of-inflammatory-arthritis-and-related-disorders
#19
REVIEW
François Jamar, Annibale Versari, Filippo Galli, Frédéric Lecouvet, Alberto Signore
Rheumatic disorders comprise a number of diseases that range from benign, mildly symptomatic degenerative disease to severe systemic disorders such as giant-cell vasculitis with dramatic consequences such as acute blindness. The former is relatively common, whereas the latter is rare. In between, commonly encountered disorders such as rheumatoid arthritis and the various spondyloarthritides, with or without peripheral enthesitis, are daily challenges for the caring physician. Clinical evaluation is of utmost importance and is constantly described under the form of specialist guidelines in all parts of the world...
May 2018: Seminars in Nuclear Medicine
https://www.readbyqxmd.com/read/29626943/new-spect-and-pet-radiopharmaceuticals-for-imaging-inflammatory-diseases-a-meta-analysis-of-the-last-10-years
#20
REVIEW
Marta Pacilio, Chiara Lauri, Daniela Prosperi, Agnese Petitti, Alberto Signore
Modern molecular nuclear medicine is rapidly developing in the field of imaging of chronic inflammatory diseases, and many new radiopharmaceuticals have been recently described and tested in animals and man. These can detect early pathophysiological changes before the development of anatomical changes and, often, before clinical onset of symptoms. This field includes new radiopharmaceuticals for SPECT and PET use to define new strategies for imaging immune cells as well as tissue modifications induced by the inflammatory process...
May 2018: Seminars in Nuclear Medicine
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