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Patrick Druwé, Koenraad G Monsieurs, Ruth Piers, James Gagg, Shinji Nakahara, Evan Avraham Alpert, Hans van Schuppen, Gábor Élő, Anatolij Truhlář, Sofie A Huybrechts, Nicolas Mpotos, Luc-Marie Joly, Theodoros Xanthos, Markus Roessler, Peter Paal, Michael N Cocchi, Conrad BjØrshol, Monika Pauliková, Jouni Nurmi, Pascual Piñera Salmeron, Radoslaw Owczuk, Hildigunnur Svavarsdóttir, Conor Deasy, Diana Cimpoesu, Marios Ioannides, Pablo Aguilera Fuenzalida, Lisa Kurland, Violetta Raffay, Gal Pachys, Bram Gadeyne, Johan Steen, Stijn Vansteelandt, Peter De Paepe, Dominique D Benoit
INTRODUCTION: Cardiopulmonary resuscitation (CPR) is often started irrespective of comorbidity or cause of arrest. We aimed to determine the prevalence of perception of inappropriate CPR of the last cardiac arrest encountered by clinicians working in emergency departments and out-of-hospital, factors associated with perception, and its relation to patient outcome. METHODS: A cross-sectional survey was conducted in 288 centres in 24 countries. Factors associated with perception of CPR and outcome were analyzed by Cochran-Mantel-Haenszel tests and conditional logistic models...
September 12, 2018: Resuscitation
Marc Schluep, Benjamin Yaël Gravesteijn, Robert Jan Stolker, Henrik Endeman, Sanne Elisabeth Hoeks
INTRODUCTION: In-hospital cardiac arrest is a major adverse event with an incidence of 1-6/1000 admissions. It has been poorly researched and data on survival is limited. The outcome of interest in IHCA research is predominantly survival to discharge, however recent guidelines warrant for more long-term outcomes. In this systematic review we sought to quantitatively summarize one-year survival after in-hospital cardiac arrest. METHODS: For this systematic review and meta-analysis we performed a systematic search of all published data on one-year survival after IHCA up to March 9th, 2018...
September 10, 2018: Resuscitation
Bradley J Petek, Christopher L Erley, Peter J Kudenchuk, David Carlbom, Jared Strote, Medley O Gatewood, William P Shuman, Ravi S Hira, Martin L Gunn, Charles Maynard, Kelley R Branch
AIM: To review data for non-invasive imaging in the diagnosis of non-traumatic out-of-hospital cardiac arrest (OHCA). DATA SOURCES: We searched MEDLINE, EMBASE, Cochrane library, and databases from inception to January 2017 for studies utilizing non-invasive imaging to identify potential causes of OHCA [computed tomography (CT), ultrasound including echocardiography, and magnetic resonance (MRI)]. STUDY SELECTION: Inclusion criteria were the following: 1) randomized control trials, cohort studies or observational studies; 2) contained a population ≥18 years old with non-traumatic OHCA who underwent diagnostic imaging with CT, MRI, echocardiography, or abdominal ultrasound; 3) imaging was obtained for diagnostic purposes; 4) patients were alive or were undergoing cardiopulmonary resuscitation at the time of imaging; 5) contained potential causes of OHCA...
September 7, 2018: Resuscitation
Johan Israelsson, Ingela Thylén, Anna Strömberg, Anders Bremer, Kristofer Årestedt
AIM: To explore factors associated with health-related quality of life (HRQoL) among cardiac arrest (CA) survivors treated with an implantable cardioverter-defibrillator (ICD) in relation to gender, and to compare their HRQoL with a general population. METHODS: This cross-sectional study included 990 adults treated with an ICD after suffering CA. All participants received a questionnaire including demographics, comorbidities and instruments to measure HRQoL (EQ-5D-3L and HADS), ICD-related concerns (ICDC), perceived control (CAS), and type D personality (DS-14)...
September 7, 2018: Resuscitation
Alain A Lipowicz, Sheldon Cheskes, Sara H Gray, Farida Jeejeebhoy, Janice Lee, Damon C Scales, Cathy Zhan, Laurie J Morrison
BACKGROUND: Incidence and survival rates after cardiac arrest among pregnant women are reported for in-hospital cardiac arrests; the incidence of maternal out-of-hospital cardiac arrest (OHCA) is unknown. Current cardiopulmonary resuscitation guidelines contain recommendations specific to this population; compliance with these has not been investigated. OBJECTIVE: To report maternal OHCA incidence, outcomes, and compliance with recommended treatment guidelines. METHODS: A population-based cohort study of consecutive maternal OHCAs from 2010 to 2014...
September 7, 2018: Resuscitation
Muhammad Usman Ali, Donna Fitzpatrick-Lewis, Meghan Kenny, Parminder Raina, Dianne L Atkins, Jasmeet Soar, Jerry Nolan, Giuseppe Ristagno, Diana Sherifali
PURPOSE: The purpose of this systematic review is to provide up-to-date evidence on effectiveness of antiarrhythmic drugs for shockable cardiac arrest to help inform the 2018 International Liaison Committee on Resuscitation Consensus on Science with Treatment Recommendations. METHODS: A search was conducted in electronic databases Medline, Embase, and Cochrane Library from inception to August 15, 2017. RESULTS: Of the 9371 citations reviewed, a total of 14 RCTs and 17 observational studies met our inclusion criteria for adult population and only 1 observational study for pediatric population...
September 1, 2018: Resuscitation
Robert Ruemmler, Alexander Ziebart, Christian Moellmann, Andreas Garcia-Bardon, Jens Kamuf, Frances Kuropka, Bastian Duenges, Erik Kristoffer Hartmann
BACKGROUND: The effects of different ventilation strategies during CPR on patient outcomes and lung physiology are still poorly understood. This study compares positive pressure ventilation (IPPV) to passive oxygenation (CPAP) and a novel ultra-low tidal volume ventilation (ULTVV) regimen in an experimental ventricular fibrillation animal model. STUDY DESIGN: Prospective randomized controlled trial. ANIMALS: 30 male German landrace pigs (16-20 weeks)...
August 31, 2018: Resuscitation
Sin Young Kim, Sang O Park, Jong Won Kim, Juno Sung, Kyeong Ryong Lee, Young Hwan Lee, Dae Young Hong, Kwang Je Baek
AIM: The cardiopulmonary resuscitation (CPR) guidelines recommend that endotracheal intubation (ETI) should be performed only by highly skilled rescuers. However, the definition of 'highly skilled' is unclear. This study evaluated how much experience with ETI is required for rescuers to perform successful ETI quickly without complications including serious chest compression interruption (interruption time <10 s) or oesophageal intubation during CPR. METHODS: This was a clinical observation study using review of CPR video clips in an urban emergency department (ED) over 2 years...
August 30, 2018: Resuscitation
Peter Radsel, Marko Noc
No abstract text is available yet for this article.
August 30, 2018: Resuscitation
Rita Patel, Manjula D Nugawela, Hannah B Edwards, Alison Richards, Hein Le Roux, Anne Pullyblank, Penny Whiting
OBJECTIVE: To evaluate the effectiveness and predictive accuracy of early warning scores (EWS) to predict deteriorating patients in pre-hospital settings. METHODS: Systematic review. Seven databases searched to August 2017. Study quality was assessed using QUADAS-2. A narrative synthesis is presented. ELIGIBILITY: Studies that evaluated EWS predictive accuracy or that compared outcomes in populations that did or did not use EWS, in any pre-hospital setting were eligible for inclusion...
August 29, 2018: Resuscitation
G D Nadarajan, L Tiah, A F W Ho, A Azazh, M K Castren, S L Chong, M J El Sayed, T Hara, B S Leong, F K Lippert, M H M Ma, Y Y Ng, H M Ohn, J Overton, P P Pek, S Perret, L A Wallis, K D Wong, M E H Ong
INTRODUCTION: The Global Resuscitation Alliance (GRA) was established in 2015 to improve survival for Out- of-Hospital Cardiac Arrest (OHCA) using the best practices developed by the Seattle Resuscitation Academy. However, these 10 programs were recommended in the context of developed Emergency Care Systems (ECS). Implementing these programs can be challenging for ECS at earlier stages of development. We aimed to explore barriers faced by developing ECS and to establish pre-requisites needed...
August 29, 2018: Resuscitation
Jason A Bartos, Kathleen Carlson, Claire Carlson, Ganesh Raveendran, Ranjit John, Tom P Aufderheide, Demetris Yannopoulos
BACKGROUND: Resuscitation of refractory out-of-hospital ventricular fibrillation/ventricular tachycardia (VF/VT) cardiac arrest using extracorporeal membrane oxygenation (ECMO) establishes a complex patient population. We aimed to describe the critical care strategies and outcomes in this population. METHODS: Between December 1, 2015 and January 1, 2018, 100 consecutive adult patients with refractory VF/VT out-of-hospital cardiac arrest and ongoing CPR were transported to the cardiac catheterization laboratory...
August 29, 2018: Resuscitation
Carolyn M Zelop, Sharon Einav, Jill M Mhyre, Steven S Lipman, Julia Arafeh, Richard E Shaw, Dana P Edelson, Farida M Jeejeebhoy
BACKGROUND: Maternal mortality has risen in the United States in the twenty-first century, yet large cohort data of maternal cardiac arrest (MCA) are limited. OBJECTIVE: We sought to describe contemporary characteristics and outcomes of in-hospital MCA. METHODS: We queried the American Heart Association's Get with the Guidelines Resuscitation voluntary registry from 2000 to 2016 to identify cases of maternal cardiac arrest. All index cardiac arrests occurring in women aged 18-50 with a patient illness category designated as obstetric or location of arrest occurring in a delivery suite were included...
August 28, 2018: Resuscitation
Jea Yeon Choi, Dongbum Suh, Do Kyun Kim, Young Ho Kwak, Jae Yun Jung, Jin Hee Lee, Jin Hee Jeong, Hyuksool Kwon, So Hyun Paek
BACKGROUND: A mid-arm circumference-based weight estimation formula has recently been proposed. The Cattermole formula, which is suggested for children aged 1-11 years, is calculated as (mid-arm circumference in cm - 10) × 3 kg. The objective of this study was to externally validate the Cattermole formula using a Korean national survey database. METHODS: The data collected from a national survey conducted in 2005 by the Korean Pediatric Society included body weight, height, age and mid-arm circumference...
August 27, 2018: Resuscitation
Min Kyun Na, Wonhee Kim, Tae Ho Lim, Bohyoung Jang, Youngsuk Cho, Kyu-Sun Choi, Hyun-Goo Shin, Chiwon Ahn, Juncheol Lee, Jae Guk Kim
AIMS: This study aimed to evaluate the prognostic accuracy of the gray matter to white matter ratio (GWR) in predicting neurological outcomes in post-cardiac arrest patients treated with target temperature management. DATA SOURCES: We systematically searched MEDLINE and EMBASE (Search date: 09/13/2017). Included studies were those evaluating neurological outcomes using the cerebral performance categories scale. We performed a subgroup analysis based on the location of the measurement...
August 27, 2018: Resuscitation
Daniela Fatuzzo, Isabelle Beuchat, Vincent Alvarez, Jan Novy, Mauro Oddo, Andrea O Rossetti
AIM: Electroencephalography (EEG) is a key modality for assessment of prognosis following cardiac arrest (CA); however, whether continuous EEG (cEEG) is superior to routine intermittent EEG (rEEG) remains debated. We examined the impact of cEEG (>18 h) vs. rEEG (<30 min) on outcome in comatose CA patients as part of multimodal prognostication. METHODS: We analysed a large prospective registry of comatose post-CA adults (n = 497; 2009-2018), stratified based on whether they received cEEG (n = 62) or rEEG (n = 435), including standardized reactivity testing at two time-points...
August 25, 2018: Resuscitation
Adam Cheng, Jonathan P Duff, David Kessler, Nancy M Tofil, Jennifer Davidson, Yiqun Lin, Jenny Chatfield, Linda L Brown, Elizabeth A Hunt
AIM: To determine if integrating a trained CPR Coach into resuscitation teams can improve CPR quality during simulated pediatric cardiopulmonary arrest (CPA). METHODS: We conducted a multicenter, prospective, randomized trial. An 18-minute simulated CPA scenario was run for resuscitation teams comprised of CPR-certified professionals from four International Network for Simulation-based Pediatric Innovation, Research & Education (INSPIRE) institutions. Forty teams (200 participants) were randomized to having a trained CPR Coach vs...
August 24, 2018: Resuscitation
Kevin Roedl, Dominik Jarczak, Sophie Becker, Valentin Fuhrmann, Stefan Kluge, Jakob Müller
BACKGROUND: The number of cardiac arrests (CA) in the group of very elderly patients (≥ 90 years) is expected to increase markedly due to the world`s rapidly ageing population. However, only little is known about long term outcome, CA- and intensive care unit (ICU) characteristics of patient's ≥ 90 years (nonagenarians) suffering from CA. METHODS: This single-center retrospective study included all adult patients ≥ 90 years after CA and return of spontaneous circulation (ROSC) which were treated at our ICU between January 1st 2008 and September 15th 2016...
August 23, 2018: Resuscitation
Claudio Sandroni, Paolo De Santis, Sonia D'Arrigo
Successful resuscitation from cardiac arrest depends on provision of adequate blood flow to vital organs generated by cardiopulmonary resuscitation (CPR). Measurement of end-tidal expiratory pressure of carbon dioxide (ETCO2 ) using capnography provides a noninvasive estimate of cardiac output and organ perfusion during cardiac arrest and can therefore be used to monitor the quality of CPR and predict return of spontaneous circulation (ROSC). In clinical observational studies, mean ETCO2 levels in patients with ROSC are higher than those in patients with no ROSC...
August 22, 2018: Resuscitation
Jainn-Jim Lin, Chia-Ying Lin, Shao-Hsuan Hsia, Huei-Shyong Wang, Ming-Chou Chiang, Kuang-Lin Lin
BACKGROUND: Recent studies suggest that a 48-h therapeutic hypothermia protocol does not improve outcomes in paediatric out-of-hospital cardiac arrest survivors. The aim of this study was to evaluate the effect of 72-h therapeutic hypothermia at 33 °C compared to normothermia at 35.5 °C-37.5 °C on outcomes and the incidence of adverse events in paediatric asphyxial out-of-hospital cardiac arrest survivors. METHODS: We conducted this retrospective cohort study at a tertiary paediatric intensive care unit between January 2010 and June 2017...
August 22, 2018: Resuscitation
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