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Reproductive Biomedicine Online

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https://www.readbyqxmd.com/read/29936089/older-women-using-their-own-eggs-issue-framed-with-two-oldest-reported-ivf-pregnancies-and-a-live-birth
#1
Norbert Gleicher, Vitaly A Kushnir, Sarah Darmon, David F Albertini, David H Barad
RESEARCH QUESTION: What level of IVF pregnancy success is currently possible in women of extremely advanced age? DESIGN: This study reports on outcomes in women aged 43-51 years at the Centre for Human Reproduction, an academically affiliated private clinical fertility and research centre in New York City. RESULTS: During the study years of 2014-2016, 16 pregnancies were established, all through day 3 transfers. Based on 'intent to treat' (cycle start), clinical pregnancy rates were 4/190 (2...
May 24, 2018: Reproductive Biomedicine Online
https://www.readbyqxmd.com/read/29857986/critical-appraisal-of-the-vienna-consensus-performance-indicators-for-assisted-reproductive-technology-laboratories
#2
María Luisa Lopez-Regalado, Luis Martínez-Granados, Antonio González-Utor, Nereyda Ortiz, Miriam Iglesias, Manuel Ardoy, Jose A Castilla
The Vienna consensus, based on the recommendations of an expert panel, has identified 19 performance indicators for assisted reproductive technology (ART) laboratories. Two levels of reference values are established for these performance indicators: competence and benchmark. For over 10 years, the Spanish embryology association (ASEBIR) has participated in the definition and design of ART performance indicators, seeking to establish specific guidelines for ART laboratories to enhance quality, safety and patient welfare...
May 24, 2018: Reproductive Biomedicine Online
https://www.readbyqxmd.com/read/30078420/the-impact-of-music-therapy-on-pain-and-stress-reduction-during-oocyte-retrieval-a-randomized-controlled-trial
#3
Cosy Wing Ching Cheung, Alice Wong Wai Yee, Pui Shan Chan, Sotirios H Saravelos, Jacqueline Pui Wah Chung, Lai Ping Cheung, Grace Wing Shan Kong, Tin-Chiu Li
RESEARCH QUESTION: Does music therapy help in reducing pain and anxiety in women undergoing transvaginal ultrasound-guided oocyte retrieval (TUGOR)? DESIGN: In this randomized controlled open label study, 209 participants were recruited and randomized into three groups (music group, n = 70; headphone group, n = 70; control group, n = 69). Patients' psychological status was assessed using the visual analogue scale of pain (VAS-P), satisfaction of pain control, state-trait anxiety inventory (STAI), Beck depression inventory (BDI), and general health questionnaire (GHQ)...
August 2018: Reproductive Biomedicine Online
https://www.readbyqxmd.com/read/30075843/response-how-pgs-pgt-a-laboratories-succeeded-in-losing-all-credibility
#4
LETTER
Santiago Munné, Sarah Yarnal, Pedro A Martinez-Ortiz, Mark Hughes, Tony Gordon
No abstract text is available yet for this article.
August 2018: Reproductive Biomedicine Online
https://www.readbyqxmd.com/read/30075842/response-how-pgs-pgt-a-laboratories-succeeded-in-losing-all-credibility
#5
LETTER
Francesca Romana Grati, Gloria Gallazzi, Lara Branca, Federico Maggi, Giuseppe Simoni, Yuval Yaron
No abstract text is available yet for this article.
August 2018: Reproductive Biomedicine Online
https://www.readbyqxmd.com/read/30075841/how-pgs-pgt-a-laboratories-succeeded-in-losing-all-credibility
#6
LETTER
Norbert Gleicher, Vitaly A Kushnir, David H Barad
No abstract text is available yet for this article.
August 2018: Reproductive Biomedicine Online
https://www.readbyqxmd.com/read/30075840/the-emperor-still-looks-naked
#7
COMMENT
Peter Braude
Preimplantation genetic screening for aneuploidy continues to excite disagreement, discussion and confusion in the field of reproductive medicine. This commentary provides a contribution to the ongoing debate.
August 2018: Reproductive Biomedicine Online
https://www.readbyqxmd.com/read/30075839/a-big-step-forward-for-pgt-m
#8
EDITORIAL
Sharyn Stock-Myer, Martin Johnson
No abstract text is available yet for this article.
August 2018: Reproductive Biomedicine Online
https://www.readbyqxmd.com/read/30075838/is-45-years-of-age-the-cut-off-for-using-autologous-oocytes
#9
EDITORIAL
John L Yovich, Michael J Chapman, Kevin N Keane, Julian Savulescu
No abstract text is available yet for this article.
August 2018: Reproductive Biomedicine Online
https://www.readbyqxmd.com/read/29807764/gene-expression-changes-in-uterine-myomas-in-response-to-ulipristal-acetate-treatment
#10
Guillaume E Courtoy, Jacques Donnez, Jérôme Ambroise, Pablo Arriagada, Mathieu Luyckx, Etienne Marbaix, Marie-Madeleine Dolmans
RESEARCH QUESTION: Does ulipristal acetate (UPA) modify the expression of genes related to apoptosis or the extracellular matrix in uterine myomas and are any modifications associated with a clinical response? DESIGN: Targeted analysis of 176 apoptosis- or extracellular-matrix-related genes was conducted using polymerase chain reaction (PCR) arrays. Relevant results were validated by quantitative PCR. Four groups were established: responsive short-term (one course, n = 9), responsive long-term (two to four courses, n = 9), non-responsive (n = 9), and the control group who was not given any hormone therapy (n = 9)...
August 2018: Reproductive Biomedicine Online
https://www.readbyqxmd.com/read/29778555/cryostorage-of-human-gametes-and-embryos-a-reckoning
#11
EDITORIAL
Mina Alikani
No abstract text is available yet for this article.
July 2018: Reproductive Biomedicine Online
https://www.readbyqxmd.com/read/29776850/what-is-the-best-protocol-to-cryopreserve-immature-mouse-testicular-cell-suspensions
#12
Jaime Onofre, Katrien Faes, Prashant Kadam, Elena Vicini, Ans M M van Pelt, Ellen Goossens
RESEARCH QUESTION: From a clinical perspective, which parameters grant optimal cryopreservation of mouse testicular cell suspensions? DESIGN: We studied the effect of different cryopreservation rates, the addition of sugars, different vessels and the addition of an apoptotic inhibitor on the efficiency of testicular cell suspension cryopreservation. After thawing and warming, testicular cell suspensions were transplanted to recipient mice for further functional assay...
July 2018: Reproductive Biomedicine Online
https://www.readbyqxmd.com/read/29759886/oocyte-retrieval-difficulties-in-women-with-ovarian-endometriomas
#13
Laura Benaglia, Andrea Busnelli, Rossella Biancardi, Walter Vegetti, Marco Reschini, Paolo Vercellini, Edgardo Somigliana
RESEARCH QUESTION: What are the frequency, characteristics and consequences of technical diffiiculties encountered by physicians when carrying out oocyte retrieval in women with ovarian endometriomas? DESIGN: We prospectively recruited women undergoing IVF and compared technical difficulties between women with (n = 56) and without (n = 227) endometriomas. RESULTS: In exposed women, the cyst had to be transfixed in eight cases (14%, 95% CI 7 to 25%) and accidental contamination of the follicular fluid with the endometrioma content was recorded in nine women (16%, 95% CI 8 to 27%)...
July 2018: Reproductive Biomedicine Online
https://www.readbyqxmd.com/read/29754985/response-scoring-of-mosaic-embryos-after-preimplantation-genetic-testing-the-rollercoaster-ride-between-fear-hope-and-embryo-wastage
#14
LETTER
Francesca Romana Grati, Gloria Gallazzi, Lara Branca, Federico Maggi, Giuseppe Simoni, Yuval Yaron
No abstract text is available yet for this article.
July 2018: Reproductive Biomedicine Online
https://www.readbyqxmd.com/read/29752003/scoring-of-mosaic-embryos-after-preimplantation-genetic-testing-a-rollercoaster-ride-between-fear-hope-and-embryo-wastage
#15
LETTER
Maximilian Murtinger, Barbara Wirleitner, Maximilian Schuff
No abstract text is available yet for this article.
July 2018: Reproductive Biomedicine Online
https://www.readbyqxmd.com/read/29731240/predicting-live-birth-for-poor-ovarian-responders-the-prosper-concept
#16
Philippe Lehert, Wai Chin, Joan Schertz, Thomas D'Hooghe, Carlo Alviggi, Peter Humaidan
RESEARCH QUESTION: A number of live-birth predictive models are available, and despite clinical interest these are rarely used owing to poor performance. In addition, no predictive models specifically for poor ovarian responders (POR) are available. The aim of the current project was to develop a clinically applicable tool for predicting live birth for PORs receiving recombinant human FSH [r-hFSH]. DESIGN: A model was developed to predict live birth in PORs receiving r-hFSH, using data from the ESPART trial...
July 2018: Reproductive Biomedicine Online
https://www.readbyqxmd.com/read/29729849/remembering-j-michael-bedford-1932-2018-a-great-thinker-and-scholar
#17
EDITORIAL
Ryuzo Yanagimachi, Mina Alikani
No abstract text is available yet for this article.
July 2018: Reproductive Biomedicine Online
https://www.readbyqxmd.com/read/29709394/clinical-practice-guidelines-for-fertility-preservation-in-young-women-undergoing-gonadotoxic-treatment-an-overview-and-critical-appraisal-of-methodological-quality-and-content
#18
Özlem Baysal, Jozefien A M Hamilton, Carl J C M Hamilton, Didi D M Braat, Catharina C M Beerendonk, Willianne L D M Nelen
RESEARCH QUESTION: What is the methodological quality and content of internationally available clinical practice guidelines (CPGs) on fertility preservation (FP) care in adult women? DESIGN: Internationally available CPGs on FP care in adult women were identified after conducting an extensive literature search and consulting (inter)national key experts. The methodological quality of the CPGs was appraised by an (inter)national panel of experts using the Appraisal of Guidelines for Research and Evaluation (AGREE) II instrument...
July 2018: Reproductive Biomedicine Online
https://www.readbyqxmd.com/read/29706285/blastocyst-vitrification-cryostorage-and-warming-does-not-affect-live-birth-rate-infant-birth-weight-or-timing-of-delivery
#19
Lucky Sekhon, Joseph A Lee, Eric Flisser, Alan B Copperman, Daniel Stein
RESEARCH QUESTION: Does vitrification and warming affect live birth rate, infant birth weight and timing of delivery? DESIGN: Retrospective, cohort study comparing outcomes of donor oocyte recipient fresh (n = 25) versus vitrified (n = 86) euploid blastocyst transfers; donor oocyte recipient singleton live births from fresh (n = 100) versus vitrified (n = 102) single embryo transfers (SET); and autologous vitrified euploid SET (n = 1760) (cryostored 21-1671 days)...
July 2018: Reproductive Biomedicine Online
https://www.readbyqxmd.com/read/29703435/very-low-anti-m%C3%A3-llerian-hormone-concentrations-are-not-an-independent-predictor-of-embryo-quality-and-pregnancy-rate
#20
Alberto Pacheco, María Cruz, Carlos Iglesias, Juan Antonio García-Velasco
RESEARCH QUESTION: Is anti-Müllerian hormone (AMH) serum concentration a useful tool to predict the outcome of assisted reproductive treatment? DESIGN: Retrospective cohort study involving 2971 patients who underwent 5570 IVF cycles. Patients were classified into six groups according to their AMH levels and analysed for associations with reproductive outcome. Several parameters of ovarian response and clinical outcome were compared between groups. RESULTS: Cancellation rate and clinical pregnancy rate varied by AMH group, with highest cancellation rates (32...
July 2018: Reproductive Biomedicine Online
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