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Reproductive Biomedicine Online

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https://www.readbyqxmd.com/read/28784335/the-vienna-consensus-report-of-an-expert-meeting-on-the-development-of-art-laboratory-performance-indicators
#1
REVIEW
(no author information available yet)
This proceedings report presents the outcomes from an international workshop supported by the European Society of Human Reproduction and Embryology (ESHRE) and Alpha Scientists in Reproductive Medicine, designed to establish consensus on definitions and recommended values for Indicators for the assisted reproductive technology (ART) laboratory. Minimum performance-level values ('competency') and aspirational ('benchmark') values were recommended for a total of 19 Indicators, including 12 Key Performance Indicators (KPIs), five Performance Indicators (PIs), and two Reference Indicators (RIs)...
August 3, 2017: Reproductive Biomedicine Online
https://www.readbyqxmd.com/read/28797742/response-rlh-versus-uhcg-supplementation-in-poor-ovarian-responders
#2
LETTER
Grace Wing Shan Kong, Jennifer Sze Man Mak, Tin Chiu Li
No abstract text is available yet for this article.
August 2, 2017: Reproductive Biomedicine Online
https://www.readbyqxmd.com/read/28802706/the-impact-of-adenomyosis-on-the-outcome-of-ivf-embryo-transfer
#3
Dimitrios Mavrelos, Tom K Holland, Oliver O'Donovan, Mohamed Khalil, George Ploumpidis, Davor Jurkovic, Yakoub Khalaf
Our study examined the impact of adenomyosis on the chance of clinical pregnancy after IVF and embryo transfer (IVF-ET). This was a prospective multicentre study from April 2013 to October 2015. We included 375 women with history of infertility who attended for a 3D scan prior to IVF-ET. A total of 150/375 (40.0%, 95% confidence interval [CI] 35.2-45.0) women had clinical pregnancy. Women with any feature of adenomyosis had a lower clinical pregnancy rate (21/72 [29.2%, 95% CI 18.6-39.6] versus 129/303 [42...
July 29, 2017: Reproductive Biomedicine Online
https://www.readbyqxmd.com/read/28802704/early-miscarriage-rate-in-lean-polycystic-ovary-syndrome-women-after-euploid-embryo-transfer-a-matched-pair-study
#4
Lu Luo, Fang Gu, Huying Jie, Chenhui Ding, Qiang Zhao, Qiong Wang, Canquan Zhou
The early miscarriage rate is reported to be higher in patients with polycystic ovary syndrome (PCOS) compared with non-PCOS patients. However, whether PCOS is an independent risk factor for early miscarriage is still controversial; to what extent embryonic aneuploidy accounts for miscarriages of PCOS is still unknown. In this 1:3 matched-pair study, 67 lean PCOS patients and 201 controls matched for age, body mass index (BMI) and embryo scores undergoing a single euploid blastocyst transfer in vitrified-warmed cycles were analysed...
July 29, 2017: Reproductive Biomedicine Online
https://www.readbyqxmd.com/read/28784336/a-prospective-randomized-controlled-trial-comparing-two-doses-of-oestrogen-therapy-after-hysteroscopic-adhesiolysis-to-prevent-intrauterine-adhesion-recurrence
#5
Jun Guo, T C Li, YuHuan Liu, EnLan Xia, Yu Xiao, FengQiong Zhou, Xue Yang
The aim of this prospective, randomized, controlled trial was to evaluate the efficacy of different doses of oestrogen treatment (2 mg and 6 mg daily) after hysteroscopic adhesiolysis in patients with moderate to severe adhesion according to the American Fertility Society (AFS) classification of intrauterine adhesions. A total of 121 patients were included in the final analysis. Fifty-nine patients received 2 mg oestrogen daily (low-dose group), and 62 received 6 mg oestrogen daily (high-dose group) for three cycles after surgery...
July 29, 2017: Reproductive Biomedicine Online
https://www.readbyqxmd.com/read/28802705/rlh-versus-uhcg-supplementation-in-poor-ovarian-responders
#6
LETTER
Emilia Richter, Wenhui Fang, Salvatore Longobardi, Thomas D'Hooghe
No abstract text is available yet for this article.
July 25, 2017: Reproductive Biomedicine Online
https://www.readbyqxmd.com/read/28781009/response-from-the-editors-first-birth-following-spindle-transfer
#7
LETTER
Mina Alikani, Bart C J Fauser, Juan Antonio García-Valesco, Joe Leigh Simpson, Martin H Johnson
No abstract text is available yet for this article.
July 20, 2017: Reproductive Biomedicine Online
https://www.readbyqxmd.com/read/28797743/importance-of-a-5-versus-7-day-pill-free-interval-in-a-gnrh-antagonist-protocol-using-corifollitropin-alfa-a-prospective-cohort-study-in-oocyte-donors
#8
Alicia Pérez-Calvo, Francisca Martínez, Christophe Blockeel, Elisabeth Clúa, Ignacio Rodríguez, Pere N Barri, Buenaventura Coroleu
In this prospective cohort study, oocyte donors were recruited prospectively and assigned to receive corifollitropin alfa: 5 days after pill discontinuation (group D5; 42 donors), or 7 days after pill discontinuation (group D7; 50 donors) in a gonadotrophin-releasing hormone antagonist protocol. Fixed additional daily doses of 200 IU recombinent FSH (rFSH) were started after 7 days of corifollitropinalfa, until triggering. No significant differences in basal characteristics were observed between both groups...
July 14, 2017: Reproductive Biomedicine Online
https://www.readbyqxmd.com/read/28756898/paving-the-way-for-a-gold-standard-of-care-for-infertility-treatment-improving-outcomes-through-standardization-of-laboratory-procedures
#9
REVIEW
William Schoolcraft, Marcos Meseguer
Infertility affects over 70 million couples globally. Access to, and interest in, assisted reproductive technologies is growing worldwide, with more couples seeking medical intervention to conceive, in particular by IVF. Despite numerous advances in IVF techniques since its first success in 1978, almost half of the patients treated remain childless. The multifactorial nature of IVF treatment means that success is dependent on many variables. Therefore, it is important to examine how each variable can be optimized to achieve the best possible outcomes for patients...
July 14, 2017: Reproductive Biomedicine Online
https://www.readbyqxmd.com/read/28756130/inositol-supplementation-in-women-with-polycystic-ovary-syndrome-undergoing-intracytoplasmic-sperm-injection-a-systematic-review-and-meta-analysis-of-randomized-controlled-trials
#10
REVIEW
Nicolás Mendoza, Laura Pérez, Tommaso Simoncini, Alessandro Genazzani
Polycystic ovary syndrome (PCOS) is a complex and heterogeneous disease that involves menstrual dysfunction and reproductive difficulty, as well as metabolic problems. The aim of this study was to assess the effectiveness of myo-inositol (MYO) and d-chiro-inositol (DCI) on improving oocyte or embryo quality and pregnancy rates for women with PCOS undergoing intracytoplasmic sperm injection (ICSI). We searched the Web of Knowledge, MEDLINE, EMBASE, Pubmed, Scopus and Cochrane databases for all articles published in any language up to March 2017...
July 14, 2017: Reproductive Biomedicine Online
https://www.readbyqxmd.com/read/28754547/first-birth-following-spindle-cell-transfer
#11
LETTER
Norbert Gleicher, Vitaly A Kushnir, David A Albertini, David H Barad
No abstract text is available yet for this article.
July 14, 2017: Reproductive Biomedicine Online
https://www.readbyqxmd.com/read/28754548/impact-of-the-outcome-of-fresh-blastocyst-transfer-on-the-subsequent-frozen-thawed-blastocyst-transfer-cycle
#12
Tarek El-Toukhy, Julia Y Kopeika, Yusuf Beebeejaun, Omar El Tokhy, Jyotsna Pundir, Yacoub Khalaf
The objective of this observational study was to assess the influence of the outcome of fresh blastocyst transfer on the success rate of the subsequent sibling frozen-thawed blastocyst transfer (FBT) cycle. In total, 1639 FBT cycles were divided into two groups: Group A (n = 698) cycles in which a positive pregnancy test result was achieved and Group B (n = 941) cycles in which no pregnancy was achieved in the preceding fresh IVF cycle. Mean age at cryopreservation, basal FSH level, number of oocytes retrieved, number of embryos transferred in the fresh cycle and survival rate of the thawed blastocysts in the FBT cycle were comparable between the two groups...
July 13, 2017: Reproductive Biomedicine Online
https://www.readbyqxmd.com/read/28751208/response-first-birth-following-spindle-cell-transfer
#13
LETTER
James A Boiani, Jacques Cohen
No abstract text is available yet for this article.
July 13, 2017: Reproductive Biomedicine Online
https://www.readbyqxmd.com/read/28733170/human-animal-chimeras-circumventing-rather-than-discussing-ethical-concerns-comes-at-a-price
#14
EDITORIAL
Wybo Dondorp, Martin H Johnson
No abstract text is available yet for this article.
July 13, 2017: Reproductive Biomedicine Online
https://www.readbyqxmd.com/read/28780381/response-first-birth-following-spindle-transfer-should-we-stay-or-should-we-go
#15
LETTER
Zitao Liu, Zaher Merhi, John Zhang, Taosheng Huang
No abstract text is available yet for this article.
July 12, 2017: Reproductive Biomedicine Online
https://www.readbyqxmd.com/read/28739334/oocyte-spindle-transfer-for-prevention-of-mitochodrial-disease-the-question-of-membrane-fusion-technique
#16
LETTER
Jan Tesarik
No abstract text is available yet for this article.
July 12, 2017: Reproductive Biomedicine Online
https://www.readbyqxmd.com/read/28733168/chimeras-intended-for-human-gamete-production-an-ethical-alternative
#17
César Palacios-González
Human eggs for basic, fertility and stem-cell research are in short supply. Many experiments that require their use cannot be carried out at present, and, therefore, the benefits that could emerge from these are either delayed or never materialise. This state of affairs is problematic for scientists and patients worldwide, and it is a matter that needs our attention. Recent advances in chimera research have opened the possibility of creating human/non-human animal chimeras intended for human gamete production (chimeras-IHGP)...
July 11, 2017: Reproductive Biomedicine Online
https://www.readbyqxmd.com/read/28736152/time-lapse-culture-with-morphokinetic-embryo-selection-improves-pregnancy-and-live-birth-chances-and-reduces-early-pregnancy-loss-a-meta-analysis
#18
REVIEW
Csaba Pribenszky, Anna-Maria Nilselid, Markus Montag
Embryo evaluation and selection is fundamental in clinical IVF. Time-lapse follow-up of embryo development comprises undisturbed culture and the application of the visual information to support embryo evaluation. A meta-analysis of randomized controlled trials was carried out to study whether time-lapse monitoring with the prospective use of a morphokinetic algorithm for selection of embryos improves overall clinical outcome (pregnancy, early pregnancy loss, stillbirth and live birth rate) compared with embryo selection based on single time-point morphology in IVF cycles...
July 10, 2017: Reproductive Biomedicine Online
https://www.readbyqxmd.com/read/28734688/ptgs2-down-regulation-in-cumulus-cells-of-infertile-women-with-endometriosis
#19
Caroline M da Luz, Michele G da Broi, Flávia Cappello Donabela, Cláudia Cristina Paro de Paz, Juliana Meola, Paula A Navarro
A deleterious effect of endometriosis on oocyte quality has been proposed. Evidence suggests that cumulus cells could be used as indirect biomarkers of oocyte quality. The PTGS2 gene, which encodes cyclooxygenase 2 (COX-2), is deregulated in endometriotic lesions and plays a crucial role in the acquisition of oocyte competence. To date, research evaluating PTGS2 expression in cumulus cells of infertile patients with endometriosis has not been conducted. The aim this study was to compare the expression levels of PTGS2 in cumulus cells of infertile women, with and without endometriosis, undergoing ovarian stimulation for intracytoplasmic sperm injection (ICSI)...
July 10, 2017: Reproductive Biomedicine Online
https://www.readbyqxmd.com/read/28733169/implications-of-the-2014-androgen-excess-and-polycystic-ovary-syndrome-society-guidelines-on-polycystic-ovarian-morphology-for-polycystic-ovary-syndrome-diagnosis
#20
J P Christ, M N Gunning, B C J M Fauser
The Androgen Excess and Polycystic Ovary Syndrome Society (AEPCOS) has recommended an updated threshold for polycystic ovarian morphology (PCOM) of 25 follicles or more, 10 ml or more of ovarian volume, or both. We describe the effect of these guidelines on reproductive and metabolic characteristics in 404 women. These women were separated into four groups: group A: hyperandrogenism and oligo-amenorrhoea (n = 157); group B: hyperandrogenism or oligo-amenorrhoea and PCOM meeting AEPCOS 2014 criteria (n = 125); group C: hyperandrogenism or oligo-amenorrhoea and PCOM meeting Rotterdam 2003 but not AEPCOS 2014 criteria (n = 72); and group D: non-PCOS not meeting either criteria (n = 50)...
July 8, 2017: Reproductive Biomedicine Online
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