journal
MENU ▼
Read by QxMD icon Read
search

Radiotherapy and Oncology: Journal of the European Society for Therapeutic Radiology and Oncology

journal
https://www.readbyqxmd.com/read/29343409/monitoring-early-changes-in-rectal-tumor-morphology-and-volume-during-5%C3%A2-weeks-of-preoperative-chemoradiotherapy-an-evaluation-with-sequential-mris
#1
Doenja M J Lambregts, Ahmed Bani Yassien, Max J Lahaye, Anja Betgen, Monique Maas, Geerard L Beets, Uulke A van der Heide, Baukelien van Triest, Regina G H Beets-Tan
PURPOSE: To assess early changes in rectal tumor volume and morphology on sequential MRIs performed during 5 weeks of chemoradiotherapy. MATERIALS AND METHODS: Thirteen patients underwent weekly T2W-MRI during 5 weeks of preoperative radiotherapy (total 50 Gy), starting after the first week of radiation. Two radiologists visually evaluated tumor volume and morphology and one reader manually segmented tumors for each time point to quantitatively calculate tumor volumes...
January 15, 2018: Radiotherapy and Oncology: Journal of the European Society for Therapeutic Radiology and Oncology
https://www.readbyqxmd.com/read/29343408/response-to-perilesional-edema-in-brain-cancer-independent-prognosticator-or-epiphenomenon-of-biomolecular-signature
#2
LETTER
Hsiang-Kuang Tony Liang, Wen-Yih Isaac Tseng
No abstract text is available yet for this article.
January 14, 2018: Radiotherapy and Oncology: Journal of the European Society for Therapeutic Radiology and Oncology
https://www.readbyqxmd.com/read/29336835/standard-whole-prostate-gland-radiotherapy-with-and-without-lesion-boost-in-prostate-cancer-toxicity-in-the-flame-randomized-controlled-trial
#3
Evelyn M Monninkhof, Juliette W L van Loon, Marco van Vulpen, Linda G W Kerkmeijer, Floris J Pos, Karin Haustermans, Laura van den Bergh, Sofie Isebaert, Gill M McColl, Robert Jan Smeenk, Juus Noteboom, Iris Walraven, Petra H M Peeters, Uulke A van der Heide
PURPOSE: To compare toxicity rates in patients with localized prostate cancer treated with standard fractionated external beam radiotherapy (EBRT) with or without an additional integrated boost to the macroscopically visible tumour. MATERIAL AND METHODS: FLAME is a phase 3 multicentre RCT (NCT01168479) of patients with pathologically confirmed localized intermediate or high-risk prostate cancer. The standard treatment arm (n = 287) received a dose to the entire prostate of 77 Gy in 35 fractions...
January 11, 2018: Radiotherapy and Oncology: Journal of the European Society for Therapeutic Radiology and Oncology
https://www.readbyqxmd.com/read/29331543/consolidation-chemotherapy-after-definite-concurrent-chemoradiation-in-patients-with-non-operable-esophageal-cancer-is-it-useful
#4
LETTER
Antoine Adenis, Florence Castan, Thierry Conroy
No abstract text is available yet for this article.
January 10, 2018: Radiotherapy and Oncology: Journal of the European Society for Therapeutic Radiology and Oncology
https://www.readbyqxmd.com/read/29331542/concurrent-chemoradiotherapy-alone-is-feasible-for-esophageal-squamous-cell-carcinoma-patients-not-suitable-for-surgery
#5
LETTER
Yongshun Chen, Jun Wang
No abstract text is available yet for this article.
January 10, 2018: Radiotherapy and Oncology: Journal of the European Society for Therapeutic Radiology and Oncology
https://www.readbyqxmd.com/read/29331541/perilesional-edema-in-brain-cancer-independent-prognosticator-or-epiphenomenon-of-biomolecular-signature
#6
LETTER
Valerio Nardone, Claudia Vinciguerra, Antonio Federico, Alfonso Cerase, Luigi Pirtoli, Paolo Tini
No abstract text is available yet for this article.
January 10, 2018: Radiotherapy and Oncology: Journal of the European Society for Therapeutic Radiology and Oncology
https://www.readbyqxmd.com/read/29317113/letter-to-the-editor-on-nevens-et-al
#7
LETTER
Olgun Elicin, Roland Giger
No abstract text is available yet for this article.
January 6, 2018: Radiotherapy and Oncology: Journal of the European Society for Therapeutic Radiology and Oncology
https://www.readbyqxmd.com/read/29310903/proton-beam-therapy-for-skull-base-chordomas-in-106-patients-a-dose-adaptive-radiation-protocol
#8
Vivien Fung, Valentin Calugaru, Stéphanie Bolle, Hamid Mammar, Claire Alapetite, Philippe Maingon, Ludovic De Marzi, Sébastien Froelich, Jean-Louis Habrand, Rémi Dendale, Georges Noël, Loïc Feuvret
BACKGROUND AND PURPOSE: To evaluate clinical results and safety of a dose adaptive protocol based on tumor volume coverage and critical structure constraints, for the treatment of skull base chordomas. MATERIAL AND METHODS: Between May 2006 and October 2012, 106 patients with skull base chordoma were treated by combined photon and proton irradiation. Prescribed dose levels were 68.4, 70.2, 72 and 73.8 Gy(RBE) in once daily fractionation of 1.8 Gy(RBE). Dose level and dosimetric constraints to organs at risk depended on postoperative residual Gross Tumor Volume (GTV) coverage...
January 6, 2018: Radiotherapy and Oncology: Journal of the European Society for Therapeutic Radiology and Oncology
https://www.readbyqxmd.com/read/29307729/upfront-vs-no-upfront-neck-dissection-in-primary-head-and-neck-cancer-radio-chemo-therapy-reply-to-elicin-et-al
#9
LETTER
Daan Nevens, Fréderic Duprez, Katrien Bonte, Philippe Deron, Wouter Huvenne, Annouschka Laenen, Wilfried De Neve, Sandra Nuyts
No abstract text is available yet for this article.
January 4, 2018: Radiotherapy and Oncology: Journal of the European Society for Therapeutic Radiology and Oncology
https://www.readbyqxmd.com/read/29306498/concurrent-chemoradiotherapy-for-bladder-cancer-practice-patterns-and-outcomes-in-the-general-population
#10
Ketan Ghate, Kelly Brennan, Safiya Karim, D Robert Siemens, William J Mackillop, Christopher M Booth
BACKGROUND: Clinical trials have shown that chemoradiotherapy (CRT) improves survival compared to radiation therapy (RT) alone in muscle-invasive bladder cancer. We describe uptake of CRT and comparative effectiveness in routine practice. METHODS: Electronic treatment records were linked to the population-based Ontario Cancer Registry to identify all patients with bladder cancer treated with curative-intent RT in 1999-2013. Modified Poisson regression was used to analyze factors associated with use of CRT...
January 3, 2018: Radiotherapy and Oncology: Journal of the European Society for Therapeutic Radiology and Oncology
https://www.readbyqxmd.com/read/29306497/short-and-long-term-risks-of-cardiovascular-disease-following-radiotherapy-in-rectal-cancer-in-four-randomized-controlled-trials-and-a-population-based-register
#11
Lingjing Chen, Sandra Eloranta, Anna Martling, Ingrid Glimelius, Martin Neovius, Bengt Glimelius, Karin E Smedby
AIM: A population-based cohort and four randomized trials enriched with long-term register data were used to clarify if radiotherapy in combination with rectal cancer surgery is associated with increased risks of cardiovascular disease (CVD). METHODS: We identified 14,901 rectal cancer patients diagnosed 1995-2009 in Swedish nationwide registers, of whom 9227 were treated with preoperative radiotherapy. Also, we investigated 2675 patients with rectal cancer previously randomized to preoperative radiotherapy or not followed by surgery in trials conducted 1980-1999...
January 3, 2018: Radiotherapy and Oncology: Journal of the European Society for Therapeutic Radiology and Oncology
https://www.readbyqxmd.com/read/29295747/comparison-of-detection-methods-for-hpv-status-as-a-prognostic-marker-for-loco-regional-control-after-radiochemotherapy-in-patients-with-hnscc
#12
Annett Linge, Ulrike Schötz, Steffen Löck, Fabian Lohaus, Cläre von Neubeck, Volker Gudziol, Alexander Nowak, Inge Tinhofer, Volker Budach, Ali Sak, Martin Stuschke, Panagiotis Balermpas, Claus Rödel, Hatice Bunea, Anca-Ligia Grosu, Amir Abdollahi, Jürgen Debus, Ute Ganswindt, Kirsten Lauber, Steffi Pigorsch, Stephanie E Combs, David Mönnich, Daniel Zips, Gustavo B Baretton, Frank Buchholz, Mechthild Krause, Claus Belka, Michael Baumann
OBJECTIVE: To compare six HPV detection methods in pre-treatment FFPE tumour samples from patients with locally advanced head and neck squamous cell carcinoma (HNSCC) who received postoperative (N = 175) or primary (N = 90) radiochemotherapy. MATERIALS AND METHODS: HPV analyses included detection of (i) HPV16 E6/E7 RNA, (ii) HPV16 DNA (PCR-based arrays, A-PCR), (iii) HPV DNA (GP5+/GP6+ qPCR, (GP-PCR)), (iv) p16 (immunohistochemistry, p16 IHC), (v) combining p16 IHC and the A-PCR result and (vi) combining p16 IHC and the GP-PCR result...
December 30, 2017: Radiotherapy and Oncology: Journal of the European Society for Therapeutic Radiology and Oncology
https://www.readbyqxmd.com/read/29291951/hypofractionated-radiation-therapy-hfrt-versus-conventional-fractionated-radiation-therapy-crt-for-newly-diagnosed-glioblastoma-patients-a-propensity-score-matched-analysis
#13
Pierina Navarria, Federico Pessina, Ciro Franzese, Stefano Tomatis, Matteo Perrino, Luca Cozzi, Matteo Simonelli, Lorenzo Bello, Elena Clerici, Marco Riva, Armando Santoro, Marta Scorsetti
BACKGROUND: The current treatment for newly diagnosed glioblastoma consists of surgery followed by conventional radiotherapy (CRT) with concomitant and adjuvant chemotherapy. Hypofractionated radiation therapy (HFRT) has been investigated and it resulted feasible and safe. The aim of this study was to evaluate whether HFRT can be comparable to CRT. MATERIALS AND METHODS: The analysis included newly diagnosed glioblastoma patients treated with CRT 60 Gy/30 fractions or HFRT 60 Gy/15 fractions...
December 29, 2017: Radiotherapy and Oncology: Journal of the European Society for Therapeutic Radiology and Oncology
https://www.readbyqxmd.com/read/29290405/ct-ventilation-imaging-derived-from-breath-hold-ct-exhibits-good-regional-accuracy-with-galligas-pet
#14
Enid M Eslick, John Kipritidis, Denis Gradinscak, Mark J Stevens, Dale L Bailey, Benjamin Harris, Jeremy T Booth, Paul J Keall
BACKGROUND AND PURPOSE: CT ventilation imaging (CTVI) derived from four dimensional CT (4DCT) has shown only moderate spatial accuracy in humans due to 4DCT image artefacts. Here we assess the accuracy of an improved CTVI using high quality exhale/inhale breath-hold CT (BHCT). MATERIALS AND METHODS: Eighteen lung cancer patients underwent exhale/inhale BHCT, 4DCT and Galligas PET ventilation scans in a single imaging session. For each BHCT and 4DCT scan, we performed deformable image registration (DIR) between the inhale and exhale phase images to quantify ventilation using three published metrics: (i) breathing induced lung density change, CTVIDIR-HU (ii) breathing induced volume change CTVIDIR-Jac and (iii) the regional air-tissue product, CTVIHU Spatial accuracy was reported as the voxel-wise Spearman correlation r between CTVI and Galligas PET...
December 28, 2017: Radiotherapy and Oncology: Journal of the European Society for Therapeutic Radiology and Oncology
https://www.readbyqxmd.com/read/29287737/response-to-stephane-renaud-et-al
#15
EDITORIAL
Wen-Chi Yang, Jin-Yuan Shih, Chao-Chi Ho, Feng-Ming Hsu
No abstract text is available yet for this article.
December 26, 2017: Radiotherapy and Oncology: Journal of the European Society for Therapeutic Radiology and Oncology
https://www.readbyqxmd.com/read/29279241/mri-evaluation-of-sacral-chordoma-treated-with-carbon-ion-radiotherapy-alone
#16
Lorenzo Preda, Davide Stoppa, Maria Rosaria Fiore, Giulia Fontana, Sofia Camisa, Roberto Sacchi, Michele Ghitti, Gisela Viselner, Piero Fossati, Francesca Valvo, Viviana Vitolo, Maria Bonora, Alberto Iannalfi, Barbara Vischioni, Alessandro Vai, Edoardo Mastella, Guido Baroni, Roberto Orecchia
BACKGROUND AND PURPOSE: To compare RECIST 1.1 with volume modifications in patients with sacral chordoma not suitable for surgery treated with carbon ions radiotherapy (CIRT) alone. To evaluate patients pain before and after CIRT. To detect if baseline Apparent Diffusion Coefficient values (ADC) from Diffusion Weighted sequences could predict response to treatment. MATERIAL AND METHODS: Patients included had one cycle of CIRT and underwent MRI before and after treatment...
December 23, 2017: Radiotherapy and Oncology: Journal of the European Society for Therapeutic Radiology and Oncology
https://www.readbyqxmd.com/read/29277447/treatment-of-advanced-nasopharyngeal-cancer-using-low-or-high-dose-concurrent-chemoradiotherapy-with-intensity-modulated-radiotherapy-a-propensity-score-matched-nationwide-population-based-cohort-study
#17
Tsung-Ming Chen, Kuan-Chou Lin, Kevin Sheng-Po Yuan, Chia-Lun Chang, Jyh-Ming Chow, Szu-Yuan Wu
BACKGROUND: No large-scale, head-to-head, phase III, randomized, controlled trial with an adequate sample size has investigated the effect of concurrent low-dose (LD) or high-dose (HD) cisplatin with radiotherapy on nasopharyngeal cancer (NPC). Thus, we conducted a propensity-score-matched, nationwide, population-based cohort study in Taiwan to investigate the outcomes of LD-concurrent chemoradiotherapy (CCRT) or HD-CCRT with intensity-modulated radiotherapy (IMRT) in patients with advanced NPC...
December 22, 2017: Radiotherapy and Oncology: Journal of the European Society for Therapeutic Radiology and Oncology
https://www.readbyqxmd.com/read/29277446/phase-i-trial-of-stereotactic-mr-guided-online-adaptive-radiation-therapy-smart-for-the-treatment-of-oligometastatic-or-unresectable-primary-malignancies-of-the-abdomen
#18
Lauren Henke, Rojano Kashani, Clifford Robinson, Austen Curcuru, Todd DeWees, Jeffrey Bradley, Olga Green, Jeff Michalski, Sasa Mutic, Parag Parikh, Jeffrey Olsen
PURPOSE/OBJECTIVES: SBRT is used to treat oligometastatic or unresectable primary abdominal malignancies, although ablative dose delivery is limited by proximity of organs-at-risk (OAR). Stereotactic, magnetic resonance (MR)-guided online-adaptive radiotherapy (SMART) may improve SBRT's therapeutic ratio. This prospective Phase I trial assessed feasibility and potential advantages of SMART to treat abdominal malignancies. MATERIALS/METHODS: Twenty patients with oligometastatic or unresectable primary liver (n = 10) and non-liver (n = 10) abdominal malignancies underwent SMART...
December 22, 2017: Radiotherapy and Oncology: Journal of the European Society for Therapeutic Radiology and Oncology
https://www.readbyqxmd.com/read/29273262/long-term-quality-of-life-in-inoperable-non-small-cell-lung-cancer-patients-treated-with-conventionally-fractionated-compared-to-hyperfractionated-accelerated-radiotherapy-results-of-the-randomized-chartwel-trial
#19
Marlene Hechtner, Mechthild Krause, Jochem König, Steffen Appold, Beate Hornemann, Susanne Singer, Michael Baumann
BACKGROUND AND PURPOSE: To evaluate the quality of life (QoL) of patients with inoperable non-small cell lung cancer treated with conventionally fractionated radiotherapy (CF) vs. continuous hyperfractionated accelerated radiotherapy weekend-less (CHARTWEL). MATERIAL AND METHODS: The largest monocentric subgroup of the phase III CHARTWEL trial was analyzed up to three years after randomization. QoL was assessed with the European Organization for Research and Treatment of Cancer QoL Core Questionnaire (QLQ-C30) and lung cancer module (QLQ-LC13) and compared using linear mixed models...
December 19, 2017: Radiotherapy and Oncology: Journal of the European Society for Therapeutic Radiology and Oncology
https://www.readbyqxmd.com/read/29273261/genotype-driven-phase-i-study-of-weekly-irinotecan-in-combination-with-capecitabine-based-neoadjuvant-chemoradiation-for-locally-advanced-rectal-cancer
#20
Ji Zhu, Xinxiang Li, Yunzhu Shen, Yun Guan, Weilie Gu, Peng Lian, Weiqi Sheng, Sanjun Cai, Zhen Zhang
PURPOSE: We aimed to identify the maximum tolerated dose (MTD) of weekly irinotecan in combination with capecitabine-based neoadjuvant chemoradiation according to the UGT1A1∗28 genotype in patients with locally advanced rectal cancer. PATIENTS AND METHODS: Patients with clinical stage T3-4, N0-2 who were eligible for preoperative chemoradiotherapy were screened for the UGT1A1∗28 genotype. Twenty-six patients with either the ∗1∗1 or ∗1∗28 genotype were eligible for dose escalation of irinotecan, and patients with a ∗28∗28 genotype were excluded...
December 19, 2017: Radiotherapy and Oncology: Journal of the European Society for Therapeutic Radiology and Oncology
journal
journal
20234
1
2
Fetch more papers »
Fetching more papers... Fetching...
Read by QxMD. Sign in or create an account to discover new knowledge that matter to you.
Remove bar
Read by QxMD icon Read
×

Search Tips

Use Boolean operators: AND/OR

diabetic AND foot
diabetes OR diabetic

Exclude a word using the 'minus' sign

Virchow -triad

Use Parentheses

water AND (cup OR glass)

Add an asterisk (*) at end of a word to include word stems

Neuro* will search for Neurology, Neuroscientist, Neurological, and so on

Use quotes to search for an exact phrase

"primary prevention of cancer"
(heart or cardiac or cardio*) AND arrest -"American Heart Association"