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Radiology

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https://www.readbyqxmd.com/read/29893650/hippocampal-calcifications-risk-factors-and-association-with-cognitive-function
#1
Esther J M de Brouwer, Remko Kockelkoren, Jules J Claus, Annemarieke de Jonghe, Mirjam I Geerlings, Thomas E F Jongsma, Willem P T M Mali, Jeroen Hendrikse, Pim A de Jong, Huiberdina L Koek
Purpose To identify risk factors for hippocampal calcifications and to investigate the association between hippocampal calcifications and cognitive function. Materials and Methods For this retrospective study, consecutive patients visiting a memory clinic at a Dutch general hospital between April 2009 and April 2015 were identified. All individuals underwent a standard diagnostic work-up including cognitive tests and brain CT. The following vascular risk factors were assessed: hypertension, diabetes mellitus, hyperlipidemia, and smoking...
June 12, 2018: Radiology
https://www.readbyqxmd.com/read/29893649/non-small-cell-lung-cancer-feasibility-of-intratumoral-radiofrequency-hyperthermia-enhanced-herpes-simplex-virus-thymidine-kinase-gene-therapy
#2
Jiansong Ji, Qiaoyou Weng, Feng Zhang, Fu Xiong, Yin Jin, Junguo Hui, Jingjing Song, Jun Gao, Minjiang Chen, Qiang Li, David Shin, Xiaoming Yang
Purpose To validate the feasibility and efficacy of intratumoral radiofrequency hyperthermia (RFH)-enhanced herpes simplex virus (HSV) thymidine kinase (TK) and ganciclovir (GCV) (hereafter, HSV-TK/GCV) gene therapy for non-small-cell lung cancer (NSCLC). Materials and Methods This study was performed from November 11, 2015, to April 14, 2017, and included (a) in vitro experiments with human NSCLC cells to establish the proof of principle, (b) in vivo experiments using mice with subcutaneous NSCLC to further demonstrate the principle, and (c) in vivo experiments using rats with orthotopic NSCLC to validate the technical feasibility...
June 12, 2018: Radiology
https://www.readbyqxmd.com/read/29893646/head-and-neck-tumors-amide-proton-transfer-mri
#3
Benjamin King Hong Law, Ann D King, Qi-Yong Ai, Darren M C Poon, Weitian Chen, Kunwar S Bhatia, Anil T Ahuja, Brigette B Ma, David Ka-Wai Yeung, Frankie Kwok Fai Mo, Yi-Xiang Wang, Jing Yuan
Purpose To evaluate the utility of amide proton transfer (APT) imaging in the characterization of head and neck tumors. Materials and Methods This retrospective study of APT imaging included 117 patients with 70 nasopharyngeal undifferentiated carcinomas (NUCs), 26 squamous cell carcinomas (SCCs), eight non-Hodgkin lymphomas (NHLs), and 13 benign salivary gland tumors (BSGTs). Normal tissues were examined in 25 patients. The APT means of malignant tumors, normal tissues, and benign tumors were calculated and compared with the Student t test and analysis of variance...
June 12, 2018: Radiology
https://www.readbyqxmd.com/read/29893645/changes-in-brain-metabolite-concentrations-after-neonatal-hypoxic-ischemic-encephalopathy
#4
Jun Shibasaki, Noriko Aida, Naho Morisaki, Moyoko Tomiyasu, Yuri Nishi, Katsuaki Toyoshima
Purpose To investigate the time-course changes and predictive utility of brain metabolite concentrations in neonatal hypoxic-ischemic encephalopathy (HIE). Materials and Methods Sixty-eight neonates (age, 35-41 gestational weeks) with HIE were admitted to a neonatal intensive care unit between September 2009 and March 2016 and examined by using proton MR spectroscopy at 18-96 hours (n = 25) and 7-14 days (n = 64) after birth (35-43 postmenstrual weeks) to estimate metabolite concentrations in the deep gray matter...
June 12, 2018: Radiology
https://www.readbyqxmd.com/read/29893644/can-amide-proton-transfer-mri-distinguish-benign-and-malignant-head-and-neck-tumors
#5
Seung Hong Choi
No abstract text is available yet for this article.
June 12, 2018: Radiology
https://www.readbyqxmd.com/read/29893643/regional-cerebral-blood-flow-in-children-and-young-adults-with-chronic-kidney-disease
#6
Hua-Shan Liu, Erum A Hartung, Abbas F Jawad, Jeffrey B Ware, Nina Laney, Allison M Port, Ruben C Gur, Stephen R Hooper, Jerilynn Radcliffe, Susan L Furth, John A Detre
Purpose To investigate the pathophysiologic effects of chronic kidney disease (CKD) on brain function in children with CKD by correlating cerebral blood flow (CBF) with clinical and behavioral indexes. Materials and Methods In this prospective study, 73 pediatric patients with CKD (mean age, 15.80 years ± 3.63; range, 9-25 years) and 57 control subjects (mean age, 15.65 years ± 3.76; range, 9-25 years) were recruited. CBF measurements were acquired with an MRI arterial spin labeling scheme. Neurocognitive measurements were performed with traditional and computerized neurocognitive batteries...
June 12, 2018: Radiology
https://www.readbyqxmd.com/read/29893642/contrast-enhanced-ct-for-colonic-diverticular-bleeding-before-colonoscopy-a-prospective-multicenter-study
#7
Shotaro Umezawa, Naoyoshi Nagata, Jun Arimoto, Shiori Uchiyama, Takuma Higurashi, Kaoru Nakano, Naoki Ishii, Toshiyuki Sakurai, Shiori Moriyasu, Yuichi Takeda, Hajime Nagase, Hirokazu Komatsu, Atsushi Nakajima, Akira Mizuki
Purpose To demonstrate the usefulness of precolonoscopy intravenous contrast material-enhanced CT for colonic diverticular bleeding (CDB). Materials and Methods A prospective, multicenter, observational study was performed. Patients with acute-onset hematochezia who were admitted to hospital were included, and those without CDB were excluded. CT was performed before colonoscopy. A Mann-Whitney U test, χ2 test, and multivariable logistic regression analysis were performed to determine the accuracy of CT before colonoscopy...
June 12, 2018: Radiology
https://www.readbyqxmd.com/read/29893641/cost-effectiveness-of-endovascular-therapy-for-acute-ischemic-stroke-a-systematic-review-of-the-impact-of-patient-age
#8
Wolfgang G Kunz, Myriam G Hunink, Konstantinos Dimitriadis, Thomas Huber, Franziska Dorn, Felix G Meinel, Bastian O Sabel, Ahmed E Othman, Maximilian F Reiser, Birgit Ertl-Wagner, Wieland H Sommer, Kolja M Thierfelder
Purpose To determine the impact of patient age on the cost-effectiveness of endovascular therapy (EVT) in addition to standard care (SC) in large-vessel-occlusion stroke for patients aged 50 to 100 years in the United States. Materials and Methods A decision-analytic Markov model was used to estimate direct and indirect lifetime costs and quality-adjusted life years (QALYs). Age-dependent input parameters were obtained from the literature. Deterministic and probabilistic sensitivity analysis for age at index stroke were used...
June 12, 2018: Radiology
https://www.readbyqxmd.com/read/29893647/the-powerful-benefit-of-endovascular-thrombectomy-for-acute-ischemic-stroke-driving-major-changes-in-stroke-systems-of-care-and-imaging-triage
#9
https://www.readbyqxmd.com/read/29869970/mapping-hypoxia-in-renal-carcinoma-with-oxygen-enhanced-mri-comparison-with-intrinsic-susceptibility-mri-and-pathology
#10
Ross A Little, Yann Jamin, Jessica K R Boult, Josephine H Naish, Yvonne Watson, Susan Cheung, Katherine F Holliday, Huiqi Lu, Damien J McHugh, Joely Irlam, Catharine M L West, Guy N Betts, Garry Ashton, Andrew R Reynolds, Satish Maddineni, Noel W Clarke, Geoff J M Parker, John C Waterton, Simon P Robinson, James P B O'Connor
Purpose To cross-validate T1-weighted oxygen-enhanced (OE) MRI measurements of tumor hypoxia with intrinsic susceptibility MRI measurements and to demonstrate the feasibility of translation of the technique for patients. Materials and Methods Preclinical studies in nine 786-0-R renal cell carcinoma (RCC) xenografts and prospective clinical studies in eight patients with RCC were performed. Longitudinal relaxation rate changes (∆R1) after 100% oxygen inhalation were quantified, reflecting the paramagnetic effect on tissue protons because of the presence of molecular oxygen...
June 5, 2018: Radiology
https://www.readbyqxmd.com/read/29869969/imaging-diagnosis-of-intrahepatic-and-perihilar-cholangiocarcinoma-recent-advances-and-challenges
#11
Ijin Joo, Jeong Min Lee, Jeong Hee Yoon
Cholangiocarcinoma, the second most common hepatobiliary malignancy after hepatocellular carcinoma, is a heterogeneous disease entity with widely varying radiologic features, clinical behavior, and treatment approaches. In the detection, characterization, staging, and resectability assessment of cholangiocarcinoma, imaging studies are indispensable. Herein, an overview of the state-of-the-art imaging techniques is presented for the evaluation of intrahepatic and perihilar cholangiocarcinoma, as well as complementary multimodality and multiparametric imaging approaches for a more comprehensive evaluation...
June 5, 2018: Radiology
https://www.readbyqxmd.com/read/29869968/murray-baron-md
#12
Arthur E Stillman, Robert M Steiner
No abstract text is available yet for this article.
June 5, 2018: Radiology
https://www.readbyqxmd.com/read/29869967/relationship-between-interstitial-lung-abnormalities-and-emphysema-in-smokers-with-and-those-without-copd
#13
Philippe A Grenier
No abstract text is available yet for this article.
June 5, 2018: Radiology
https://www.readbyqxmd.com/read/29869966/radiology-responding-to-rapid-changes-in-our-field
#14
David A Bluemke
No abstract text is available yet for this article.
June 5, 2018: Radiology
https://www.readbyqxmd.com/read/29869965/high-resolution-three-dimensional-and-cinematic-rendering-mr-neurography
#15
Jan Fritz, Shivani Ahlawat
No abstract text is available yet for this article.
June 5, 2018: Radiology
https://www.readbyqxmd.com/read/29869964/three-dimensional-in-vivo-us-of-7-week-embryo
#16
Amaury Boleis, Caroline Diguisto
No abstract text is available yet for this article.
June 5, 2018: Radiology
https://www.readbyqxmd.com/read/29869963/does-fractal-analysis-of-the-right-side-of-the-heart-provide-insight-into-pulmonary-hypertension
#17
James C Moon, Gabriella Captur
No abstract text is available yet for this article.
June 5, 2018: Radiology
https://www.readbyqxmd.com/read/29869962/effect-of-screening-mammography-on-other-preventive-services-in-older-women
#18
Gary J Whitman, Scott B Cantor
No abstract text is available yet for this article.
June 5, 2018: Radiology
https://www.readbyqxmd.com/read/29869961/digital-mammography-versus-digital-mammography-plus-tomosynthesis-for-breast-cancer-screening-the-reggio-emilia-tomosynthesis-randomized-trial
#19
Pierpaolo Pattacini, Andrea Nitrosi, Paolo Giorgi Rossi, Valentina Iotti, Vladimiro Ginocchi, Sara Ravaioli, Rita Vacondio, Luca Braglia, Silvio Cavuto, Cinzia Campari
Purpose To compare digital mammography (DM) plus digital breast tomosynthesis (DBT) versus DM alone for breast cancer screening in the Reggio Emilia Tomosynthesis trial, a two-arm test-and-treat randomized controlled trial. Materials and Methods For this trial, eligible women (45-70 years old) who previously participated in the Reggio Emilia screening program were invited for mammography. Consenting women were randomly assigned 1:1 to undergo DBT+DM or DM (both of which involved two projections and double reading)...
June 5, 2018: Radiology
https://www.readbyqxmd.com/read/29869960/female-human-spines-with-simulated-osteolytic-defects-ct-based-structural-analysis-of-vertebral-body-strength
#20
Ron Alkalay, Robert Adamson, Alexander Miropolsky, David Hackney
Purpose To evaluate a CT structural analysis protocol (SAP) for estimating the strength of human female cadaveric spines with lytic lesions. Materials and Methods Osteolytic foci was created in the middle vertebra of 44 thoracic and lumbar three-level segments from 11 female cadavers (age range, 50-70 years). The segments underwent CT by using standard clinical protocol and their failure strength was assessed at CT SAP. The spines were mechanically tested to failure in pure axial compression or in compression with torsion...
June 5, 2018: Radiology
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