Amy E Flowers, Tania L Gonzalez, Yizhou Wang, Chintda Santiskulvong, Ekaterina L Clark, Allynson Novoa, Caroline A Jefferies, Kate Lawrenson, Jessica L Chan, Nikhil V Joshi, Yazhen Zhu, Hsian-Rong Tseng, Erica T Wang, Mariko Ishimori, S Ananth Karumanchi, John Williams, Margareta D Pisarska
INTRODUCTION: Fetal sex affects fetal and maternal health outcomes in pregnancy, but this connection remains poorly understood. As the placenta is the route of fetomaternal communication and derives from the fetal genome, placental gene expression sex differences may explain these outcomes. OBJECTIVES: We utilized next generation sequencing to study the normal human placenta in both sexes in first and third trimester to generate a normative transcriptome based on sex and gestation...
March 21, 2024: Placenta