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Pediatrics

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https://www.readbyqxmd.com/read/28916591/continuous-glucose-monitoring-in-very-preterm-infants-a-randomized-controlled-trial
#1
Alfonso Galderisi, Andrea Facchinetti, Garry M Steil, Paulina Ortiz-Rubio, Francesco Cavallin, William V Tamborlane, Eugenio Baraldi, Claudio Cobelli, Daniele Trevisanuto
BACKGROUND AND OBJECTIVES: Impaired glucose control in very preterm infants is associated with increased morbidity, mortality, and poor neurologic outcome. Strategies based on insulin titration have been unsuccessful in achieving euglycemia in absence of an increase in hypoglycemia and mortality. We sought to assess whether glucose administration guided by continuous glucose monitoring (CGM) is more effective than standard of care blood glucose monitoring in maintaining euglycemia in very preterm infants...
September 15, 2017: Pediatrics
https://www.readbyqxmd.com/read/28916590/us-emergency-department-trends-in-imaging-for-pediatric-nontraumatic-abdominal-pain
#2
Lauren M Niles, Monika K Goyal, Gia M Badolato, James M Chamberlain, Joanna S Cohen
OBJECTIVES: To describe national emergency department (ED) trends in computed tomography (CT) and ultrasound imaging for the evaluation of pediatric nontraumatic abdominal pain from 2007 through 2014. METHODS: We used data from the National Hospital Ambulatory Medical Care Survey to measure trends in CT and ultrasound use among children with nontraumatic abdominal pain. We performed multivariable logistic regression to measure the strength of the association of ED type (pediatric versus general ED) with CT and ultrasound use adjusting for potential confounding variables...
September 15, 2017: Pediatrics
https://www.readbyqxmd.com/read/28912368/neurodevelopment-of-hiv-exposed-and-hiv-unexposed-uninfected-children-at-24-months
#3
Sumona Chaudhury, Paige L Williams, Gloria K Mayondi, Jean Leidner, Penny Holding, Vicki Tepper, Sharon Nichols, Jane Magetse, Maureen Sakoi, Kebaiphe Moabi, Joseph Makhema, Charlotte Mdluli, Haruna Jibril, George R Seage, Betsy Kammerer, Shahin Lockman
BACKGROUND: We sought to determine if HIV-exposed uninfected (HEU) children had worse neurodevelopmental outcomes at 24 months compared with HIV-unexposed uninfected (HUU) children in Botswana. METHODS: HIV-infected and uninfected mothers enrolled in a prospective observational study ("Tshipidi") in Botswana from May 2010 to July 2012. Child neurodevelopment was assessed at 24 months with the Bayley Scales of Infant and Toddler Development, Third Edition (Bayley-III: cognitive, gross motor, fine motor, expressive language, and receptive language domains) and the Development Milestones Checklist (DMC), a caregiver-completed questionnaire (locomotor, fine motor, language and personal-social domains)...
September 14, 2017: Pediatrics
https://www.readbyqxmd.com/read/28912367/lessons-from-pediatric-hiv-a-case-for-curative-intent-in-pediatric-cancer-in-lmics
#4
REVIEW
Henry Miller, Jeremy S Slone, Eric Raabe, Nader Kim El-Mallawany, Parth Mehta, B Ryan Phelps
No abstract text is available yet for this article.
September 14, 2017: Pediatrics
https://www.readbyqxmd.com/read/28904072/validation-of-a-novel-assay-to-distinguish-bacterial-and-viral-infections
#5
Isaac Srugo, Adi Klein, Michal Stein, Orit Golan-Shany, Nogah Kerem, Irina Chistyakov, Jacob Genizi, Oded Glazer, Liat Yaniv, Alina German, Dan Miron, Yael Shachor-Meyouhas, Ellen Bamberger, Kfir Oved, Tanya M Gottlieb, Roy Navon, Meital Paz, Liat Etshtein, Olga Boico, Gali Kronenfeld, Eran Eden, Robert Cohen, Helène Chappuy, François Angoulvant, Laurence Lacroix, Alain Gervaix
BACKGROUND: Reliably distinguishing bacterial from viral infections is often challenging, leading to antibiotic misuse. A novel assay that integrates measurements of blood-borne host-proteins (tumor necrosis factor-related apoptosis-inducing ligand, interferon γ-induced protein-10, and C-reactive protein [CRP]) was developed to assist in differentiation between bacterial and viral disease. METHODS: We performed double-blind, multicenter assay evaluation using serum remnants collected at 5 pediatric emergency departments and 2 wards from children ≥3 months to ≤18 years without (n = 68) and with (n = 529) suspicion of acute infection...
September 13, 2017: Pediatrics
https://www.readbyqxmd.com/read/28904071/assessing-the-febrile-child-for-serious-infection-a-step-closer-to-meaningful-rapid-results
#6
David W Kimberlin, Claudette L Poole
No abstract text is available yet for this article.
September 13, 2017: Pediatrics
https://www.readbyqxmd.com/read/28899986/perioperative-spending-on-spinal-fusion-for-scoliosis-for-children-with-medical-complexity
#7
Jay G Berry, Michael Glotzbecker, Jonathan Rodean, Izabela Leahy, Joanne Cox, Sara J Singer, Margaret O'Neill, Matt Hall, Lynne Ferrari
BACKGROUND: Global payment is used with surgeries to optimize health, lower costs, and improve quality. We assessed perioperative spending on spinal fusion for scoliosis to inform how this might apply to children. METHODS: Retrospective analysis of 1249 children using Medicaid and aged ≥5 years with a complex chronic condition undergoing spinal fusion in 2013 from 12 states. From perioperative health services measured 6 months before and 3 months after spinal fusion, we simulated a spending reallocation with increased preoperative care and decreased hospital care...
September 12, 2017: Pediatrics
https://www.readbyqxmd.com/read/28893851/synthetic-cannabinoid-use-among-high-school-seniors
#8
Joseph J Palamar, Monica J Barratt, Leigh Coney, Silvia S Martins
OBJECTIVES: In this study, we examined the prevalence and correlates of current synthetic cannabinoid (SC) use among high school seniors in the United States. METHODS: Monitoring the Future, an annual nationally representative survey of high school seniors, began querying current (30-day) SC use in 2014. Data were examined from the 2 most recent cohorts (2014-2015; N = 7805). Prevalence of self-reported use was examined and differences in demographics and recency and frequency of other drug use was compared between current marijuana-only users and current SC (plus marijuana) users using χ(2) and generalized linear model using Poisson...
September 11, 2017: Pediatrics
https://www.readbyqxmd.com/read/28893850/age-legislation-and-off-road-vehicle-injuries-in-children
#9
Michael R Flaherty, Toby Raybould, Cassandra M Kelleher, Raghu Seethala, Jarone Lee, Haytham M A Kaafarani, Peter T Masiakos
BACKGROUND AND OBJECTIVES: In 2010, the Massachusetts Legislature passed a comprehensive law that restricted off-road vehicle (ORV) use by children <14 years old and regulated ORV use by children up to the age of 18 years. We aimed to examine the impact of the 2010 Massachusetts law on the rates of ORV-related injuries. METHODS: A retrospective analysis was performed of Massachusetts emergency department (ED) and inpatient discharges between 2002 and 2013 as found in the Center for Health Information and Analysis database by using external causes of injury codes specific to ORV-related injuries...
September 11, 2017: Pediatrics
https://www.readbyqxmd.com/read/28885171/gestational-age-and-outcomes-in-critical-congenital-heart-disease
#10
Martina A Steurer, Rebecca J Baer, Roberta L Keller, Scott Oltman, Christina D Chambers, Mary E Norton, Shabnam Peyvandi, Larry Rand, Satish Rajagopal, Kelli K Ryckman, Anita J Moon-Grady, Laura L Jelliffe-Pawlowski
BACKGROUND AND OBJECTIVES: It is unknown how gestational age (GA) impacts neonatal morbidities in infants with critical congenital heart disease (CCHD). We aim to quantify GA-specific mortality and neonatal morbidity in infants with CCHD. METHODS: Cohort study using a database linking birth certificate, infant hospital discharge, readmission, and death records, including infants 22 to 42 weeks' GA without chromosomal anomalies (2005-2012, 2 988 925 live births)...
September 8, 2017: Pediatrics
https://www.readbyqxmd.com/read/28882877/clinical-pathway-produces-sustained-improvement-in-acute-gastroenteritis-care
#11
Lori Rutman, Eileen J Klein, Julie C Brown
BACKGROUND AND OBJECTIVES: Despite widespread use of the rotavirus vaccine in the last decade, dehydrating illnesses impact almost 2 billion children worldwide annually. Evidence supports oral rehydration therapy as a first-line treatment of mild to moderate dehydration. Ondansetron has proven to be a safe and effective adjunct in children with vomiting. We implemented a clinical pathway in our pediatric emergency department (ED) in January 2005 to improve care for this common condition...
September 7, 2017: Pediatrics
https://www.readbyqxmd.com/read/28882876/post-up-study-postpartum-depression-screening-in-well-child-care-and-maternal-outcomes
#12
Angarath I van der Zee-van den Berg, Magda M Boere-Boonekamp, Catharina G M Groothuis-Oudshoorn, Maarten J IJzerman, Riet M E Haasnoot-Smallegange, Sijmen A Reijneveld
OBJECTIVES: Postpartum depression often remains unaddressed. Screening in well-child care (WCC) may improve early detection, promote maternal recovery, and reduce effects on child development. We assessed the effectiveness of screening for postpartum depression in WCC compared with care as usual (CAU) on outcomes at mother and child levels. METHODS: In a prospective, quasiexperimental, comparative design, mothers visiting Dutch WCC centers were exposed either to screening at 1, 3, and 6 months postpartum (n = 1843) or to CAU (n = 1246)...
September 7, 2017: Pediatrics
https://www.readbyqxmd.com/read/28877999/sudden-cardiac-arrest-while-eating-a-hot-dog-a-rare-presentation-of-brugada-syndrome-in-a-child
#13
Isa Ozyilmaz, Bedir Akyol, Yakup Ergul
Patients who are diagnosed with Brugada syndrome (BS) usually experience sudden cardiac arrest (SCA) and arrhythmia when they have a high fever, consume alcohol, and, more frequently, during their night sleep. In some rare cases, an SCA can be seen depending on a possible vagal stimulus, such as eating a large bite of food. We describe a 9-year-old patient who had a sudden cardiac attack while he was eating a large hot dog. After successful resuscitation, a suspicious ST elevation in V2 was seen in his electrocardiographic evaluation...
September 6, 2017: Pediatrics
https://www.readbyqxmd.com/read/28877998/respiratory-infections-and-the-risk-of-celiac-disease
#14
Renata Auricchio, Donatella Cielo, Renato de Falco, Martina Galatola, Valentina Bruno, Basilio Malamisura, Maria Giovanna Limongelli, Riccardo Troncone, Luigi Greco
BACKGROUND AND OBJECTIVES: The increasing incidence of celiac disease (CD) suggests that common infections before the onset of autoimmune diseases could be an important factor in switching the immune response. We aimed to explore the relationship between early clinical events and the development of CD in genetically predisposed infants. METHODS: In this study, 373 newborns from families with at least 1 relative with CD were recruited, and human leukocyte antigen DQ2- or DQ8-positive infants were followed up with clinical and serological evaluations...
September 6, 2017: Pediatrics
https://www.readbyqxmd.com/read/28872047/doing-more-about-health-care-disparities-moving-past-description-to-action
#15
Marvin B Harper
No abstract text is available yet for this article.
September 5, 2017: Pediatrics
https://www.readbyqxmd.com/read/28872046/racial-and-ethnic-differences-in-antibiotic-use-for-viral-illness-in-emergency-departments
#16
Monika K Goyal, Tiffani J Johnson, James M Chamberlain, T Charles Casper, Timothy Simmons, Evaline A Alessandrini, Lalit Bajaj, Robert W Grundmeier, Jeffrey S Gerber, Scott A Lorch, Elizabeth R Alpern
BACKGROUND AND OBJECTIVES: In the primary care setting, there are racial and ethnic differences in antibiotic prescribing for acute respiratory tract infections (ARTIs). Viral ARTIs are commonly diagnosed in the pediatric emergency department (PED), in which racial and ethnic differences in antibiotic prescribing have not been previously reported. We sought to investigate whether patient race and ethnicity was associated with differences in antibiotic prescribing for viral ARTIs in the PED...
September 5, 2017: Pediatrics
https://www.readbyqxmd.com/read/28870977/recommendations-for-prevention-and-control-of-influenza-in-children-2017-2018
#17
(no author information available yet)
This statement updates the recommendations for routine use of the seasonal influenza vaccine and antiviral medications for the prevention and treatment of influenza in children. The American Academy of Pediatrics recommends annual seasonal influenza immunization for everyone 6 months and older, including children and adolescents. Highlights for the upcoming 2017-2018 season include the following:1. Annual universal influenza immunization is indicated with either a trivalent or quadrivalent (no preference) inactivated vaccine;2...
September 4, 2017: Pediatrics
https://www.readbyqxmd.com/read/28864554/dietary-supplements-isotretinoin-and-liver-toxicity-in-adolescents-a-retrospective-case-series
#18
Cynthia Marie Carver DeKlotz, Keith D Roby, Sheila Fallon Friedlander
Isotretinoin is the most effective acne therapy available, but has the potential for a number of adverse side effects, including transaminitis. The iPLEDGE isotretinoin program recommends avoiding some herbals and supplements due to potential side effects. However, little is known about the effects of protein supplements on the liver, particularly in patients taking isotretinoin. We designed a retrospective chart review to evaluate the symptoms, diagnosis, treatment, and outcome of patients on or preparing to take isotretinoin therapy who were concurrently ingesting protein or herbal supplementation and who developed transaminitis...
September 1, 2017: Pediatrics
https://www.readbyqxmd.com/read/28864553/language-matters-identifying-medically-complex-children-in-foster-care
#19
Erin P Williams, Rebecca R Seltzer, Renee D Boss
No abstract text is available yet for this article.
September 1, 2017: Pediatrics
https://www.readbyqxmd.com/read/28851740/patient-and-researcher-engagement-in-health-research-a-parent-s-perspective
#20
Israel Amirav, Virginia Vandall-Walker, Jananee Rasiah, Laura Saunders
No abstract text is available yet for this article.
August 29, 2017: Pediatrics
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