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Pediatric Surgery International

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https://www.readbyqxmd.com/read/29214342/editorial
#1
EDITORIAL
Prem Puri
No abstract text is available yet for this article.
December 6, 2017: Pediatric Surgery International
https://www.readbyqxmd.com/read/29214341/sternocostal-slipping-rib-syndrome
#2
Patrick C Bonasso, Shannon N Petrus, Samuel D Smith, Richard J Jackson
PURPOSE: Classical slipping rib syndrome (SRS) can be subclassified based on anatomical location. We describe our experience with three patients suffering from symptomatic sternocostal slipping rib syndrome (SCSRS), a much less common variant of SRS. METHODS: This was a retrospective review of patients with SRS from 1988 to 2016. Described is our experience. RESULTS: Of 44 patients identified with SRS, three patients underwent operations for SCSRS variant...
December 6, 2017: Pediatric Surgery International
https://www.readbyqxmd.com/read/29196881/gata-6-expression-is-decreased-in-diaphragmatic-and-pulmonary-mesenchyme-of-fetal-rats-with-nitrofen-induced-congenital-diaphragmatic-hernia
#3
Toshiaki Takahashi, Florian Friedmacher, Julia Zimmer, Prem Puri
PURPOSE: Congenital diaphragmatic hernia (CDH) and associated pulmonary hypoplasia are thought to be caused by a malformation of the underlying diaphragmatic and airway mesenchyme. GATA binding protein 6 (Gata-6) is a zinc finger-containing transcription factor that plays a crucial role during diaphragm and lung development. In the primordial diaphragm, Gata-6 expression is restricted to mesenchymal compartments of the pleuroperitoneal folds (PPFs). In addition, Gata-6 is essential for airway branching morphogenesis through upregulation of mesenchymal signaling...
December 2, 2017: Pediatric Surgery International
https://www.readbyqxmd.com/read/29196880/role-of-intestinal-hsp70-in-barrier-maintenance-contribution-of-milk-to-the-induction-of-hsp70-2
#4
Rebecca M Rentea, Yuee Guo, Xiaorong Zhu, Mark W Musch, Eugene B Chang, David M Gourlay, Jennifer L Liedel
BACKGROUND: Necrotizing enterocolitis (NEC) is a gastrointestinal disease of complex etiology resulting in devastating systemic inflammation and often death in premature newborns. We previously demonstrated that formula feeding inhibits ileal expression of heat shock protein-70 (Hsp70), a critical stress protein within the intestine. Barrier function for the premature intestine is critical. We sought to determine whether reduced Hsp70 protein expression increases neonatal intestinal permeability...
December 1, 2017: Pediatric Surgery International
https://www.readbyqxmd.com/read/29188379/inguinal-hernia-repair-by-bianchi-incision-in-boys-a-retrospective-study
#5
Junshan Lin, Dumiao Li, Jinwen Chen, Li Lin, Yali Xu
OBJECTIVE: Open inguinal hernia repair by Bianchi incision is a potential alternative technique for the treatment of IH. This study aims to retrospectively analyze boys with IH, who underwent open IH repair by Bianchi incision. METHODS: A total of 3300 boys (1-144 months) with IH from April 2007 to September 2015 were enrolled into this study. An open high scrotal incision (Bianchi incision) to ligate the processus proximal to the internal inguinal ring was performed in patients for IH repair...
November 29, 2017: Pediatric Surgery International
https://www.readbyqxmd.com/read/29177625/hydrometrocolpos-etiology-and-management-past-beckons-the-present
#6
REVIEW
Kashish Khanna, Shilpa Sharma, D K Gupta
Hydrometrocolpos is a rare condition in which the uterus and the vagina are grossly distended with a retained fluid other than pus or blood. It may present during the neonatal period or later at puberty. Most cases reported earlier were stillbirths and were diagnosed only on autopsy. Antenatal diagnosis is now possible with the advent of ultrasound. An early diagnosis and speedy management is the key to survival. Many previous case reports have focused on the varied clinical presentations, multiple causes, associated syndromes and/or the radiological diagnosis of this condition...
November 24, 2017: Pediatric Surgery International
https://www.readbyqxmd.com/read/29170900/the-challenges-of-closing-an-ileostomy-in-patients-with-total-intestinal-aganglionosis-after-small-bowel-transplant
#7
Fereshteh Salimi Jazi, Tiffany J Sinclair, Chad M Thorson, Ricardo Castillo, Andrew C Bonham, Carlos O Esquivel, Matias Bruzoni
We present the case of a 14-year-old male with a history of small bowel transplantation for long segment Hirschsprung's disease who underwent Duhamel ileorectal pull-through procedure. In post-transplant, the patient had no restrictions and was not TPN-dependent. To improve his quality of life, he and his family were interested in closing the ileostomy and undergoing pull-through surgery. The complexity of the case includes the presence of an aganglionic rectal segment-a short root of the mesentery due to the small bowel transplant-and significant immunosuppression...
November 23, 2017: Pediatric Surgery International
https://www.readbyqxmd.com/read/29167984/x-ray-micro-computed-tomography-in-pediatric-surgery-a-new-tool-for-studying-embryos
#8
Susann Brosig, N Peukert, R Metzger, H Schneider, R Haak, J Gosemann, M Lacher, D Kluth
PURPOSE: The embryology of common congenital malformations is discussed controversially. Studies are hampered by a shortage of study material and techniques which require partial or complete preparation and therewith destruction of embryos. X-ray micro-computed-tomography (µCT) is a technical opportunity keeping the embryos intact. Thus, the aim of this study was to assess the applicability of µCT in embryonic research compared to the anatomical information obtained by scanning electron microscopy (SEM)...
November 22, 2017: Pediatric Surgery International
https://www.readbyqxmd.com/read/29159423/characterizing-pediatric-surgical-capacity-in-the-eastern-democratic-republic-of-congo-results-of-a-pilot-study
#9
Sarah B Cairo, Luc Malemo Kalisya, Richard Bigabwa, David H Rothstein
PURPOSE: Characterize pediatric surgical capacity in the eastern Democratic Republic of Congo (DRC) to identify areas of potential improvement. METHODS: The Pediatric Personnel, Infrastructure, Procedures, Equipment, and Supplies (PediPIPES) survey was used in two representative eastern DRC provinces to assess existing surgical infrastructure and capacity. We compared our results to previously published reports from other sub-Saharan African countries. RESULTS: Fourteen hospitals in the eastern DRC and 37 in 19 sub-Saharan African (SSA) countries were compared...
November 20, 2017: Pediatric Surgery International
https://www.readbyqxmd.com/read/29138922/extraspinal-sacrococcygeal-ependymoma-masquerading-as-sacrococcygeal-teratoma-in-the-pediatric-patient
#10
Ruchi Amin, Elizabeth Berdan, Jeffrey Knipstein, Jason Jarzembowski, Sabina Siddiqui
No abstract text is available yet for this article.
November 14, 2017: Pediatric Surgery International
https://www.readbyqxmd.com/read/29134395/choledochal-malformation-terminology-and-aetiology
#11
LETTER
Filippo Parolini, Mark Davenport
No abstract text is available yet for this article.
November 13, 2017: Pediatric Surgery International
https://www.readbyqxmd.com/read/29128874/the-initial-prophylactic-antibiotic-usage-and-subsequent-necrotizing-enterocolitis-in-high-risk-premature-infants-a-systematic-review-and-meta-analysis
#12
Xue Fan, Li Zhang, Jun Tang, Chao Chen, Juan Chen, Yi Qu, Dezhi Mu
OBJECTIVE: To investigate the correlation between the initial prophylactic antibiotic use and the subsequent NEC in high-risk premature infants. METHODS: We performed a literature search of PubMed, EMBASE, the Cochrane Central Register of Controlled Trials (CENTRAL), and the Web of Science, and nine studies with a total of 5207 infants were selected for inclusion in this study. RESULTS: The pooled estimate for the seven studies combined indicating that prophylactic antibiotic usage was associated with a non-significant trend toward increased incidence of NEC [odds ratio (OR) 0...
November 11, 2017: Pediatric Surgery International
https://www.readbyqxmd.com/read/29124404/pediatric-patients-receiving-naloxone-within-48%C3%A2-h-of-anesthesia-a-case-control-study
#13
Vinay K Donempudi, Juraj Sprung, Toby N Weingarten
PURPOSE: Excessive narcotization in pediatric surgical patients has not been well characterized. This report describes the use of postoperative naloxone in pediatric patients. METHODS: Pediatric surgical patients from January 1, 2010, through June 30, 2016, who underwent general anesthesia and received naloxone within 48 h postoperatively were identified and matched 1:1 with controls by age, sex, and procedure. Cases and controls underwent retrospective chart review...
November 9, 2017: Pediatric Surgery International
https://www.readbyqxmd.com/read/29124403/esophagoesophagopexy-technique-for-assisted-fistulization-of-esophageal-atresia
#14
Isabelle Chumfong, Hanmin Lee, Benjamin E Padilla, Tippi C MacKenzie, Lan T Vu
PURPOSE: We describe our experience using a modified suture fistula technique for addressing tension in longer gap esophageal atresia (EA). Esophagoesophagopexy (EEP) is the tacking of the proximal and distal ends of esophageal pouches without formal anastomosis. In this retrospective cohort, we review the outcomes of patients with EA after EEP. METHODS: We reviewed the operative reports of EA cases treated at our institution from 1997 to 2016 and identified all patients described as having EEP...
November 9, 2017: Pediatric Surgery International
https://www.readbyqxmd.com/read/29124402/presence-of-viable-germ-cells-in-testicular-regression-syndrome-remnants-is-routine-excision-indicated-a-systematic-review
#15
REVIEW
Ramesh Mark Nataraja, Evie Yeap, Costa J Healy, Inderpal S Nandhra, Feilim L Murphy, John M Hutson, Chris Kimber
There is no consensus in the literature about the necessity for excision of testicular remnants in the context of surgery for an impalpable testis and testicular regression syndrome (TRS). The incidence of germ cells (GCs) within these nubbins varies between 0 and 16% in previously published series. There is a hypothetical potential future malignancy risk, although there has been only one previously described isolated report of intratubular germ-cell neoplasia. Our aim was to ascertain an accurate incidence of GCs and seminiferous tubules (SNTs) within excised nubbins and hence guide evidence-based practice...
November 9, 2017: Pediatric Surgery International
https://www.readbyqxmd.com/read/29124401/bronchoscopic-assessments-and-clinical-outcomes-in-pediatric-patients-with-tracheomalacia-and-bronchomalacia
#16
Yuichi Okata, Tomomi Hasegawa, Yuko Bitoh, Kosaku Maeda
BACKGROUND: Tracheomalacia and bronchomalacia (TM/BM) are one of the serious causes of airway obstruction in infants and children. This study reviewed our bronchoscopic assessments and clinical outcomes in pediatric patients with TM/BM, and investigated risk factors of surgical intervention for TM/BM. METHODS: Fifty-seven consecutive patients who were diagnosed as TM/BM by bronchoscopy between 2009 and 2013 were reviewed retrospectively. They were divided into two groups according to the presence (group E, n = 26) or absence (group N, n = 31) of acute life-threatening events and extubation failure (ALTE/EF)...
November 9, 2017: Pediatric Surgery International
https://www.readbyqxmd.com/read/29124400/characterization-of-m1-and-m2-polarization-of-macrophages-in-vascularized-human-dermo-epidermal-skin-substitutes-in-vivo
#17
Agnes S Klar, Katarzyna Michalak-Mićka, Thomas Biedermann, Claudia Simmen-Meuli, Ernst Reichmann, Martin Meuli
AIMS AND OBJECTIVES: Vascularized bio-engineered human dermo-epidermal skin substitutes (vascDESS) hold promise for treating burn patients, including those with severe full-thickness wounds. We have previously shown that vascDESS promote wound healing by enhanced influx of macrophages and granulocytes. Immediately following transplantation, macrophages infiltrate the graft and differentiate into a pro-inflammatory (M1) or a pro-healing M2 phenotype. The aim of this study was to characterize the activation state of macrophages infiltrating skin transplants at distinct time points following transplantation...
November 9, 2017: Pediatric Surgery International
https://www.readbyqxmd.com/read/29119252/image-based-surgical-risk-factors-for-wilms-tumor
#18
Takaharu Oue, Akihiro Yoneda, Noriaki Usui, Takashi Sasaki, Masahiro Zenitani, Natsumi Tanaka, Shuichiro Uehara, Soji Ibuka, Yuichi Takama, Hiroomi Okuyama
PURPOSE: The standard treatment for Wilms tumor (WT) is primary resection. However, in cases with unresectable tumor or tumor spillage, which are considered to have high surgical risks, more intensive chemotherapy and radiotherapy are required. In the present study, we retrospectively analyzed preoperative image parameters to identify factors associated with surgical risks. METHODS: Twenty-nine patients with WT were enrolled in this study. Data on various preoperative image parameters, such as tumor size, tumor volume, displacement of great vessels, and contralateral extension of the tumor were collected, and their relationship with surgical factors, including operative time, hemorrhage, tumor spillage, and unresectability were analyzed...
November 8, 2017: Pediatric Surgery International
https://www.readbyqxmd.com/read/29119251/postoperative-complications-and-long-term-functional-outcome-in-children-operated-for-idiopathic-rectal-prolapse
#19
Elin Albertsdottir, Niels Qvist
PURPOSE: The aim of the present study was to evaluate the postoperative complications and the long-term gastrointestinal functional outcome after surgical treatment for rectal prolapse on a strategy with stapled anopexy for short (< 5 cm) prolapse and Delormes procedure for longer (> 5 cm) rectal prolapse. METHODS: A total of 38 patients were included with a postoperative follow-up period ranging from 1 month to 9.1 years. Thirty patients (83%) completed the Rome III questionnaire on gastrointestinal function, with the follow-up period ranging from 2 months to 7 years...
November 8, 2017: Pediatric Surgery International
https://www.readbyqxmd.com/read/29094201/a-review-of-genetic-factors-contributing-to-the-etiopathogenesis-of-anorectal-malformations
#20
REVIEW
Kashish Khanna, Shilpa Sharma, Noel Pabalan, Neetu Singh, D K Gupta
BACKGROUND: Anorectal malformation (ARM) is a common congenital anomaly with a wide clinical spectrum. Recently, many genetic and molecular studies have been conducted worldwide highlighting the contribution of genetic factors in its etiology. We summarize the current literature on such genetic factors. MATERIALS AND METHODS: Literature search was done using different combinations of terms related to genetics in anorectal malformations. From 2012 to June 2017, articles published in the English literature and studies conducted on human population were included...
November 1, 2017: Pediatric Surgery International
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