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Pediatric Surgery International

Takahiro Korai, Katsunori Kouchi, Ayako Takenouchi, Aki Matsuoka, Kiyoaki Yabe, Chikako Nakata
PURPOSE: We aimed at investigating the incidence and risk factors of non-IgE-mediated gastrointestinal food allergies (non-IgE-GI-FAs) in neonates and infants. METHODS: A total of 126 infants who underwent neonatal gastrointestinal surgeries were grouped into those with (n = 13) and those without an onset of non-IgE-GI-FAs (n = 113). The characteristics of the two groups (e.g., birth weight, delivery type, small intestinal surgeries, and pre-/postoperative nutrition) were compared...
August 14, 2018: Pediatric Surgery International
Juma Obayashi, Shigeyuki Furuta, Takuya Kawaguchi, Kohei Kawaguchi, Kei Ohyama, Hideki Nagae, Munechika Wakisaka, Hiroaki Kitagawa
BACKGROUND: We investigated the efficacy of broad-spectrum antibiotics for prevention of postoperative intra-abdominal abscess in pediatric acute appendicitis with our 3 risk factors:-WBC > 16.5 (× 103 /µl), CRP > 3.1 (mg/dl) and appendix maximum short diameter on diagnostic imaging > 11.4 mm. METHODS: Four hundred twenty-two patients were reviewed. Patients with 0-1 risk factors were assessed as low-risk and those with 2-3 were high-risk...
August 14, 2018: Pediatric Surgery International
Giuseppe Lauriti, Gabriele Lisi, Pierluigi Lelli Chiesa, Augusto Zani, Agostino Pierro
Neurologically impaired children (NIC) suffer severe gastroesophageal reflux (GER) with poor fundoplication outcome. Aims of the study were: (1) to determine the recurrence of GER after fundoplication in NIC; (2) to compare fundoplication versus gastro-jejunal tube feeding insertion (GJ) and fundoplication versus total esophagogastric dissociation (TEGD) in primarily treating GER in NIC. Using defined search strategy, two investigators identified all comparative studies reporting the mentioned procedures to primarily treat GER in NIC...
August 13, 2018: Pediatric Surgery International
Thomas A Boyle, Kittu A Rao, Davis B Horkan, Marguerite L Bandeian, Juan E Sola, Charles A Karcutskie, Casey Allen, Eduardo A Perez, Edward B Lineen, Anthony R Hogan, Holly L Neville
BACKGROUND: Unintentional injury is the leading cause of death in children and adolescents. Injuries occurring during boating and recreational water sports are poorly described in the literature. Herein, we compare injuries from water sports to those resulting from motor vehicle collisions, which are better described in existing literature. METHODS: A retrospective review of 1935 consecutive pediatric trauma patients, as defined by age < 18 years, admitted to a single level-1 pediatric trauma center between January 2000 and August 2013 was performed...
August 13, 2018: Pediatric Surgery International
Masaya Yamoto, Akiyoshi Nomura, Koji Fukumoto, Toshiaki Takahashi, Kengo Nakaya, Akinori Sekioka, Yutaka Yamada, Naoto Urushihara
PURPOSE: The aim of this study was to investigate the risk factors for in hospital mortality in infants with esophageal atresia (EA) without critical chromosome abnormality disorders and develop a new prognostic classification to assess the influence of external risk factors on the prognosis of EA, which could provide more effective treatment strategies in clinical practice. METHODS: A retrospective chart review of all consecutive patients between January 1994 and December 2017, which included 65 EA infants who were admitted to Shizuoka Children's Hospital, was conducted...
August 11, 2018: Pediatric Surgery International
Yoshiko Usui, Shigeru Ono, Katsuhisa Baba, Yuki Tsuji
PURPOSE: Congenital tracheal stenosis (CTS) is rare and challenging. Complete tracheal rings cause a wide spectrum of airway-obstructing lesions and varying degrees of respiratory distress. Although surgical reconstruction is the primary option for symptomatic CTS, sometimes an appropriate management strategy may be difficult due to other anomalies. We aimed to identify pitfalls in the management of CTS. METHODS: We retrospectively reviewed the records of patients with CTS during the last 10 years in our institution...
August 11, 2018: Pediatric Surgery International
Yuko Bitoh, Yuichi Okata, Jiro Tsugawa, Harunori Miyauchi, Yosuke Aida, Yumiko Tachibanaki, Yumiko Nakai, Yuichiro Tomioka
PURPOSE: Treatment strategies and clinical outcomes of subglottic stenosis (SGS) in children are varied due to the degree and range of stenotic lesions. The optimal surgical procedure for SGS in children is still under debate. The aim of this study was to evaluate the clinical outcomes of our anterior-posterior cricoid (APC) split technique combined with long-term T-tube stenting for grade II or III SGS in children. METHODS: A retrospective chart review of children with SGS between January 2011 and December 2016 was conducted...
August 10, 2018: Pediatric Surgery International
Victor M Salinas-Torres, Rafael A Salinas-Torres, Ricardo M Cerda-Flores, Hugo L Gallardo-Blanco, Laura E Martínez-de-Villarreal
BACKGROUND: Gastroschisis has been assumed to have a low rate of syndromic and primary malformations. We aimed to systematically review and explore the frequency and type of malformations/chromosomal syndromes and to identify significant biological/genetic roles in gastroschisis. METHODS: Population-based, gastroschisis-associated anomalies/chromosomal defects published 1950-2018 (PubMed/MEDLINE) were independently searched by two reviewers. Associated anomalies/chromosomal defects and selected clinical characteristics were subdivided and pooled by race, system/region, isolated, and associated cases (descriptive analysis and chi-square test were performed)...
August 9, 2018: Pediatric Surgery International
Hui Xiao, Rui Huang, Long Chen, Mei Diao, Long Li
BACKGROUND: The detailed embryonic etiology and pathogenesis of anorectal malformations (ARMs) remains unclear. Recent studies have shown that gene expression abnormalities were the key factors that result in ARMs. Long non-coding RNAs (lncRNAs) were reported as the 'transcriptional noise' within the genome. The expression profiles of lncRNA and mRNA remain less characterized in the pathogenesis of ARMs. Furthermore, the function of lncRNAs in the regulation of this process has not been investigated so far...
August 7, 2018: Pediatric Surgery International
Chiyoe Shirota, Keisuke Suzuki, Hiroo Uchida, Hiroshi Kawashima, Akinari Hinoki, Takahisa Tainaka, Wataru Sumida, Naruhiko Murase, Kazuo Oshima, Kosuke Chiba, Satoshi Makita, Yujiro Tanaka
PURPOSE: Anovestibular fistula (AVF) is the most common type of anorectal malformation in females. Delayed anorectoplasty with fistula dilatation is commonly performed during infancy; however, we have been actively performing anorectoplasty in neonates. We report the surgical complications and postoperative defecation function associated with single-stage anorectoplasty performed in neonates. METHODS: Patients who underwent surgery for AVF between 2007 and 2017 at two institutions were retrospectively studied...
August 6, 2018: Pediatric Surgery International
Ryuta Masuya, Tatsuru Kaji, Motoi Mukai, Kazuhiko Nakame, Takafumi Kawano, Seiro Machigashira, Waka Yamada, Koji Yamada, Shun Onishi, Keisuke Yano, Tomoe Moriguchi, Koshiro Sugita, Masato Kawano, Hiroyuki Noguchi, Masaya Suzuhigashi, Mitsuru Muto, Satoshi Ieiri
PURPOSE: While the diagnosis and outcomes of esophageal atresia (EA) have improved, associated anomalies, the management of late complications and growth remain major issues. We analyzed factors that affected the prognosis, late complications and growth. METHODS: We retrospectively reviewed EA patients treated at two centers from 1984 to 2016. Patient characteristics, complications (gastroesophageal reflux [GER], anastomotic stenosis, tracheomalacia, dysphagia) and growth were evaluated...
August 6, 2018: Pediatric Surgery International
Hisako Kuyama, Sadashige Uemura, Atsushi Yoshida, Mayumi Yamamoto
PURPOSE: The aim of this study was to show the difference between the pulmonary function of children with mild or severe types of pectus excavatum (PE) and post-operative changes in their predicted vital capacity (%VC) following Nuss procedure. PATIENTS AND METHODS: One hundred and twenty-four of the 208 children who underwent Nuss procedure for PE between January 2007 and March 2016 were deemed eligible for this study and evaluated retrospectively. A spirometry was performed on these children on four occasions: before operation; pre-bar removal; and 1 month and 1 year after bar removal...
August 6, 2018: Pediatric Surgery International
Neetu Singh, Devendra Kumar Gupta, Shilpa Sharma, Dinesh Kumar Sahu, Archana Mishra, Devendra Kumar Yadav, Jiledar Rawat, Arun Kumar Singh
BACKGROUND: The genetic association of hypospadias-risk studies has been conducted in Caucasians, Chinese-Han populations and few in Indian populations. However, no comprehensive approach has been followed to assess genetic involvement in the severity of the disorder. METHODS: The study evaluated to establish the correlation between genotyped single nucleotide and copy number variants (SNPs/CNVs) and severity of hypospadias by an association in a total 30 SNPs in genes related to sex hormone-biosynthesis and metabolism; embryonic-development and phospholipase-D-signalling pathways on 138 surgery-confirmed hypospadias-cases from North India (84 penile and 28 cases of penoscrotal-hypospadias as compared with 31 cases of glanular + coronal), and analyzed and identified CNVs in four familial cases (18 members) and three paired-sporadic cases (6 members) using array-based comparative-genomic-hybridization and validated in 32 hypospadias samples by TaqMan assay...
August 4, 2018: Pediatric Surgery International
Yutaka Kanamori, Toshihiko Watanabe, Tohru Yorifuji, Michiya Masue, Hideyuki Sasaki, Masaki Nio
PURPOSE: Congenital hyperinsulinism is a rare disease, and the newly developed 18 fluoro-L -dihydroxyphenylalanine-positron emission tomography (18F-DOPA PET) examination can detect hyperplastic lesions. Our purpose was to report the results of a nationwide survey on surgical treatment of congenital hyperinsulinism in Japan. METHODS: A questionnaire was sent to the 159 accredited and affiliated training institutes certified as pediatric surgical institutes by the Japanese Association of Pediatric Surgeons, asking if they had encountered patients who underwent surgical treatment for congenital hyperinsulinism after 18F-DOPA PET examination from 2000 to 2017...
August 3, 2018: Pediatric Surgery International
Hiroaki Fukuzawa, Naoto Urushihara, Chisato Miyakoshi, Keisuke Kajihara, Insu Kawahara, Kaori Isono, Yoshitomo Samejima, Shizu Miura, Kotaro Uemura, Keiichi Morita, Makoto Nakao, Akiko Yokoi, Koji Fukumoto, Masaya Yamoto, Kosaku Maeda
PURPOSE: This study aimed to investigate the clinical features and risk factors of bile duct perforation in pediatric congenital biliary dilatation (CBD) patients. METHODS: CBD patients, whose initial symptom was abdominal pain, were enrolled in this study and were divided into perforated and non-perforated groups. The clinical features of the perforated group were investigated. Moreover, the age at operation, sex, and morphologic features of the extrahepatic bile duct were compared between the groups...
August 3, 2018: Pediatric Surgery International
Eric H Rosenfeld, Adam Vogel, Robert T Russell, Ilan Maizlin, Denise B Klinkner, Stephanie Polites, Barbara Gaines, Christine Leeper, Stallion Anthony, Megan Waddell, Shawn St Peter, David Juang, Rajan Thakkar, Joseph Drews, Brandon Behrens, Mubeen Jafri, Randall S Burd, Marianne Beaudin, Laurence Carmant, Richard A Falcone, Suzanne Moody, Bindi J Naik-Mathuria
PURPOSE: Determining the integrity of the pancreatic duct is important in high-grade pancreatic trauma to guide decision making for operative vs non-operative management. Computed tomography (CT) is generally an inadequate study for this purpose, and magnetic resonance cholangiopancreatography (MRCP) is sometimes obtained to gain additional information regarding the duct. The purpose of this multi-institutional study was to directly compare the results from CT and MRCP for evaluating pancreatic duct disruption in children with these rare injuries...
August 3, 2018: Pediatric Surgery International
Kazuki Yokota, Hiroo Uchida, Takahisa Tainaka, Yujiro Tanaka, Chiyoe Shirota, Akinari Hinoki, Takazumi Kato, Wataru Sumida, Kazuo Oshima, Kosuke Chiba, Tetsuya Ishimaru, Hiroshi Kawashima
PURPOSE: The Soave procedure (SO) is performed most commonly for Hirschsprung disease. SO reduces the risk of injury to the pelvic structures; however, a residual aganglionic muscle cuff could interfere with bowel movement and lead to obstructive enterocolitis. The Swenson procedure is considered ideal in terms of peristalsis. Currently, laparoscopic surgery provides better visualization and facilitates precise dissection, possibly leading to feasible performance of the laparoscopic modified Swenson procedure (SW)...
August 2, 2018: Pediatric Surgery International
Yujiro Tanaka, Takahisa Tainaka, Wataru Sumida, Akinari Hinoki, Chiyoe Shirota, Naruhiko Murase, Kazuo Oshima, Ryo Shirotsuki, Kosuke Chiba, Hiroo Uchida
PURPOSE: We previously showed that meticulous probing and resection of the intrahepatic bile duct stenosis (IHBDS)-causing membrane or septum was effective in preventing hepatolithiasis after choledochal cyst excisions in open surgeries. Then, we introduced this maneuver into laparoscopic choledochal cyst excisions in 2014 and performed routine resections since then. The aim of this study was to show the feasibility of this method in laparoscopic surgery. METHODS: We retrospectively reviewed the demographics and outcomes of patients who underwent laparoscopic choledochal cyst excisions at our hospital between January 2014 and December 2017...
August 2, 2018: Pediatric Surgery International
Jun Fujishiro, Kan Suzuki, Miho Watanabe, Chizue Uotani, Toshiko Takezoe, Naohiro Takamoto, Kentaro Hayashi
PURPOSE: Infants with Alagille syndrome (AGS) frequently develop neonatal cholestasis, and some AGS infants who suspected of biliary atresia subsequently undergo the Kasai operation with the diagnosis of biliary atresia. The aim of this study was to investigate the effect of the Kasai operation on liver and patient outcomes among AGS patients, using a meta-analysis. METHODS: A systematic review and meta-analysis of studies describing the outcomes of AGS patients with/without the Kasai operation were conducted...
August 2, 2018: Pediatric Surgery International
Alexander C Small, Alejandra Perez, Jayant Radhakrishnan, Stanley Desire, Philip Zachariah, Lisa C Creelman, Shumyle Alam
PURPOSE: Children who undergo lower urinary tract reconstruction (LUTR) often have asymptomatic bacteriuria or recurrent urinary tract infections (UTI). We aimed to determine the prevalence of positive preoperative urine cultures (PPUC) before LUTR and to analyze any impact on postoperative outcomes. METHODS: This retrospective review included all pediatric LUTR procedures utilizing bowel segments performed by one surgeon over 2 years. Preoperative cultures were obtained 1-2 days before surgery...
August 1, 2018: Pediatric Surgery International
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