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Pediatric Surgery International

Yun-Lin Ye, Fu-Fu Zheng, Dong Chen, Ji Zhang, Zhuo-Wei Liu, Zi-Ke Qin, Fang-Jian Zhou
PURPOSE: To evaluate risk factors of relapse in pediatric patients with clinical stage I (CS1) testicular yolk sac tumors. METHODS: With retrospective analysis, the medical records of children with pure testicular yolk sac tumors who were referred to Sun Yat-sen University Cancer Center and The First Affiliated Hospital from January 1995 to December 2015 were selected and recorded. Histopathology and staging were retrieved and multivariate analysis was performed with SPSS 20...
December 11, 2018: Pediatric Surgery International
Josephine Reismann, D Schädlich, M I Minderjahn, K Rothe, M Reismann
PURPOSE: We have recently shown that uncomplicated phlegmonous appendicitis is characterized by independent inflammatory patterns based on significant eosinophilia in children aged 7-17 years. However, clinical decision-making based on inflammatory values is not easy, especially due to the dynamics of inflammation over time. The present study was performed to evaluate the basic distinguishability of the inflammatory entities by laboratory values over time based on an extended patient number with children aged 0-17 years...
December 7, 2018: Pediatric Surgery International
Joseph A Sujka, Katrina L Weaver, Justin A Sobrino, Ashwini Poola, Katherine W Gonzalez, Shawn D St Peter
BACKGROUND: Post-operative intra-abdominal abscess (PIAA) is the most common complication after appendectomy for perforated appendicitis (PA). Typically, intravenous antibiotics by a peripherally inserted venous catheter are utilized to treat the abscess. We sought to evaluate the role of oral antibiotics in this population. METHODS: This is a retrospective review conducted of children between January 2005 and September 2015 with a PIAA. Demographics, clinical course, complications, and follow-up were analyzed using descriptive statistics...
December 3, 2018: Pediatric Surgery International
Lina Schollin Ask, Jan F Svensson, Ola Olén, Åke Örtqvist
PURPOSE: Intussusception has been associated with rotavirus vaccine. The rotavirus vaccine will soon be introduced in the Swedish national immunization program. A validation of the diagnosis of intussusception among Swedish children in the Swedish National Patient Register is needed, as a basis for future vaccine safety surveillance by Swedish registers. METHODS: This diagnostic study reviewed the medical admission records of 392 Swedish children with intussusception from 1987 to 2013...
November 26, 2018: Pediatric Surgery International
Weiwei Jiang, GuangLin Chen, Jie Zhang, Xiaofeng Lv, Changgui Lu, Huan Chen, Wei Li, Hongxing Li, Qiming Geng, Xiaoqun Xu, Weibing Tang
BACKGROUND: There are many advantages of a SMOF emulsion (SMOF-lipid), such as liver-protective properties and anti-inflammatory effects. The objective of this study was to compare the clinical outcomes of SMOF-lipid with medium-chain triglycerides (MCT) /long-chain triglycerides (LCT) in infants after intestinal surgery. METHODS: This was a prospective, randomized study. Neonates receiving intravenous nutrient solution, including lipid emulsion after gastrointestinal surgery, were included in this study...
November 24, 2018: Pediatric Surgery International
Elisabet Gustafson, Therese Larsson, Johan Danielson
PURPOSE: The aim of this study was to assess the function and quality of life of Hirschsprung's Disease (HD) beyond adolescence and relate it to matched controls. METHODS: All 203 patients diagnosed with HD at our department from 1961 to 1995 were identified. 21 had died, 43 had unclear diagnosis and 16 could not be traced. The remaining 123 patients were sent bowel function and SF-36 quality of life questionnaires. 69 patients (mean age 37.8, range 22-58, 13 female) responded and were matched with 138 age and sex-matched controls...
November 20, 2018: Pediatric Surgery International
Satoshi Obata, Koichiro Yoshimaru, Kosuke Kirino, Tomoko Izaki, Satoshi Ieiri, Atsuyuki Yamataka, Tsugumichi Koshinaga, Jun Iwai, Hitoshi Ikeda, Hiroshi Matsufuji, Yoshinao Oda, Tomoaki Taguchi
PURPOSE: Acquired isolated hypoganglionosis (A-IH) is a late-onset intestinal pseudo-obstruction disorder and shows different pathophysiological findings from congenital isolated hypoganglionosis (C-IH). In this study, we retrospectively examined five cases of A-IH and investigated the features of A-IH. METHODS: Five cases of A-IH were extracted from a nationwide retrospective cohort study in 10 years, from which totally 355 cases of Allied Disorders of Hirschsprung's Disease (ADHD) were collected...
November 19, 2018: Pediatric Surgery International
Louis A Carrillo, Akshita Kumar, Matthew T Harting, Claudia Pedroza, Charles S Cox
PURPOSE: New guidelines have been proposed for venous thromboembolism (VTE) prophylaxis in pediatric trauma patients. This paper seeks to evaluate risk factors associated with VTE that might further guide patient selection for prophylaxis. METHODS: Review of a tertiary children's academic hospital's trauma database for VTE events and associated risk factors from 2005 to 2016. RESULTS: 15,306 pediatric trauma patients were identified and reviewed...
November 19, 2018: Pediatric Surgery International
Xueqiang Yan, Houfang Kuang, Zhenchuang Zhu, Haibin Wang, Jun Yang, Xufei Duan, Hongqiang Bian, Nannan Zheng, Xuyong Chen
OBJECTIVE: The aim of this study was to investigate the pathogenesis, symptoms and individualized surgical management in pediatrics with gastroduodenal perforation (GDP). METHODS: Patients diagnosed with GDP from January 2013 to December 2016 in our hospital were collected and divided into gastric perforation (GP) group and duodenal perforation (DP) group. Demographics, clinical events, etiological factors, symptoms, the time from symptom onset to operation, intraoperative findings and surgical procedures were analyzed...
November 17, 2018: Pediatric Surgery International
Elisa Zambaiti, Federico Scottoni, Eleonora Rizzi, Simone Russo, Koichi Deguchi, Simon Eaton, Alessandro F Pellegata, Paolo De Coppi
BACKGROUND: Conditions leading to reduced gastric volume are difficult to manage and are associated to poor quality-of-life. Stomach augmentation using a tissue-engineered stomach is a potential solution to restore adequate physiology and food reservoir. Aim of this study was to evaluate the decellularisation of whole rat stomach using a detergent-enzymatic protocol. METHODS: Stomachs harvested from rats were decellularised through luminal and vascular cannulation using 24-h detergent-enzymatic treatment and completely characterized by appropriate staining, DNA and Extracellular matrix -component quantifications...
November 16, 2018: Pediatric Surgery International
Katie W Russell, Michael L Nance, N Scott Adzick, Pablo Laje
AIM OF THE STUDY: To evaluate the incidence of respiratory failure requiring ECMO in newborns with gastroschisis (GC), compare it to the incidence in the general population, review the surgical outcomes of newborns with GC requiring ECMO and compare them to newborns with GC not requiring ECMO. METHODS: This is a retrospective review of all neonatal admissions for GC from December 2010 to September 2015. MAIN RESULTS: 110 newborns with GC were admitted to our NICU between 12/2010 and 9/2015; 36 were term...
November 16, 2018: Pediatric Surgery International
Alberto Peña, Andrea Bischoff
No abstract text is available yet for this article.
November 15, 2018: Pediatric Surgery International
T Maluleke, H Mangray, M Arnold, H A Moore, S W Moore
INTRODUCTION: Visceral myopathies remain difficult and frustrating clinical entities, a distinctive form of acquired degenerative visceral myopathy, African degenerative leiomyopathy, a myogenic functional intestinal obstruction without aganglionosis which affects smooth muscle of the intestine, in young indigenous African children. The Actin G2 gene is the main gene encoding smooth muscle actin found in enteric tissues. Recent research has identified Actin G2 alpha gene variation as an important causative biomarker in visceral myopathies and megacystis microcolon...
November 15, 2018: Pediatric Surgery International
Tiffany J Zens, Andrew Rogers, Randi Cartmill, Daniel Ostlie, Bridget L Muldowney, Peter Nichol, Jonathan E Kohler
PURPOSE: Umbilical hernias are common in young children. Many resolve spontaneously by age four with very low risk of symptoms or incarceration. Complications associated with surgical repair of asymptomatic umbilical hernias have not been well elucidated. We analyzed data from one hospital to test the hypothesis that repair at younger ages is associated with increased complication rates. METHODS: A retrospective chart review of all umbilical hernia repairs performed during 2007-2015 was conducted at a tertiary care children's hospital...
November 14, 2018: Pediatric Surgery International
Katarzyna Micka-Michalak, Thomas Biedermann, Ernst Reichmann, Martin Meuli, Agnes S Klar
PURPOSE: Ultraviolet (UV) radiation adversely affects skin health at cellular and molecular levels. Hence, UV radiation can directly induce inflammatory responses in the dermis by inducing erythema, edema, inflammation, dermal fibroblasts alterations, and extracellular matrix modifications. METHODS: Human keratinocytes, melanocytes, and fibroblasts were isolated from skin biopsies, cultured, and expanded in vitro. Fibroblasts were seeded into collagen type I hydrogels that were subsequently covered by keratinocytes and melanocytes...
November 14, 2018: Pediatric Surgery International
Suniah S Ayub, Michelle Zeidan, Shawn D Larson, Saleem Islam
PURPOSE: Severe constipation and encopresis are significant problems in the pediatric population. Medical management succeeds in 50-70%; however, surgical considerations are necessary for the remainder such as the antegrade continence enema (ACE). The purpose of this study is to assess the long-term outcomes following the ACE procedure. METHODS: All patients undergoing an ACE over a 14-year period were included. Data on clinical conditions, treatments, and outcomes were collected...
November 13, 2018: Pediatric Surgery International
Adam M Vogel, Jingwen Zhang, Patrick D Mauldin, Regan F Williams, Eunice Y Huang, Matthew T Santore, Kuojen Tsao, Richard A Falcone, M Sidney Dassinger, Jeffrey H Haynes, Martin L Blakely, Robert T Russell, Bindi J Naik-Mathuria, Shawn D St Peter, David Mooney, Jeffrey S Upperman, Christian J Streck
PURPOSE: To describe the practice pattern for routine laboratory and imaging assessment of children following blunt abdominal trauma (BAT). METHODS: Children (age < 16 years) presenting to 14 pediatric trauma centers following BAT over a 1-year period were prospectively identified. Injury, demographic, routine laboratory and imaging utilization data were collected. Descriptive, comparative, and correlation analysis was performed. RESULTS: 2188 children with a median age of 8 (4,12) years were included and the median injury severity score was 5 (1,10)...
November 13, 2018: Pediatric Surgery International
Rachel Harwood, Fraser Horwood, Violeta Tafilaj, Ross J Craigie
PURPOSE: To determine the impact of intra-operative Trans-anastomotic Tube (TAT) placement on the cost of post-operative nutrition in infants with congenital duodenal obstruction (CDO). METHODS: A retrospective analysis of patients undergoing corrective surgery for CDO, with birth-weight over 1.5 kg over a 10-year period. Data are presented as median (inter-quartile range) and analysed with Mann-Whitney U test and Fisher's exact test as appropriate. RESULTS: 59 patients were included...
November 11, 2018: Pediatric Surgery International
Katie A Fritz, Ayman Y Khmour, Krista Kitzerow, Thomas T Sato, Mir A Basir
PURPOSE: Congenital diaphragmatic hernia (CDH) survivors experience increased risk of medical and neurodevelopmental challenges. This study describes the health-related quality of life (HRQOL), special education utilization and the family impact among neonatal CDH survivors. METHODS: A single-center prospective cohort of CDH survivors born between 1995 and 2006 was followed. Parents completed the PedsQL HRQOL index and a Family Impact survey to assess the need for medical equipment, home health services, and special education and quantify the burden placed on the family by their child's medical needs...
November 11, 2018: Pediatric Surgery International
Joshua S O'Connell, Maarten Janssen Lok, Hiromu Miyake, Shogo Seo, Edoardo Bindi, Mashriq Alganabi, Agostino Pierro
AIM OF STUDY: The repair of esophageal atresia (EA) carries an increased risk of anastomotic leak and stricture formation, especially in patients with anastomotic tension. To minimize this risk, pediatric surgeons perform elective post-operative muscle paralysis, positive-pressure ventilation, and head flexion (PVF) to reduce movement and tension at the anastomosis. We systematically reviewed and analyzed the effect of post-operative PVF on reducing anastomotic complications. METHODS: Embase, MEDLINE, Web of Science, and PubMed databases were used to conduct searches...
November 10, 2018: Pediatric Surgery International
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