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Pediatric Surgery International

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https://www.readbyqxmd.com/read/28434039/outcome-of-stoma-closure-in-babies-with-necrotising-enterocolitis-early-vs-late-closure
#1
Debasish Bijoykrishna Banerjee, Hasanthi Vithana, Shilpa Sharma, Thomas Tat Ming Tsang
Newborns undergoing surgery for necrotizing enterocolitis (NEC) often require a stoma. Currently, there is no consensus regarding the best time for stoma closure (SC). Our aim was to determine the outcomes of early versus late closure. METHODS: Retrospective analysis of patients who underwent SC following stoma formation for NEC between Jan 2009 and July 2015 was done. Early (EC) versus late closure (LC) was defined as less than 10 weeks versus at or after 10 weeks of stoma formation...
April 22, 2017: Pediatric Surgery International
https://www.readbyqxmd.com/read/28432433/glypican-3-mrna-expression-level-in-wilms-tumor-correlation-with-histological-type-stage-and-outcome
#2
Md Nahidul Wari, Archana George Vallonthaiel, Aijaz Ahmed, Deepali Saxena, Venkateswaran K Iyer, Sandeep R Mathur, Sandeep Agarwala, Sameer Bakhshi, V Srinivas, P Chattopadhyaya, Arundhati Sharma, S Datta Gupta, Amit Dinda
PURPOSE: To correlate expression of Glypican-3 in Wilms tumor with histopathology, stage, and outcome. METHODS: Glypican-3 mRNA expression by real-time PCR on tumor and normal germline samples from 75 fresh nephrectomies for Wilms tumor with fold change after normalization against GAPDH was compared. Survival analysis for event-free and overall survival (EFS, OS) with 2-year follow-up for Glypican-3 overexpression (>1.5 times) and clinicopathological parameters was performed...
April 21, 2017: Pediatric Surgery International
https://www.readbyqxmd.com/read/28424863/current-practice-regarding-timing-of-patent-processus-vaginalis-ligation-for-idiopathic-hydrocele-in-young-boys-a-survey-of-uk-surgeons
#3
Matthew Jobson, Nigel J Hall
PURPOSE: The aim of this study was to determine the current UK practice regarding timing of surgical repair of hydroceles in young boys. METHODS: Through a validated, online survey, participants were asked their preferred management option in five different clinical scenarios across five age ranges. RESULTS: 71 responses were included in the analysis. The most common age to offer surgical intervention for a congenital hydrocele that is stable or increasing in size, or a hydrocele of the cord is 24-36 months...
April 19, 2017: Pediatric Surgery International
https://www.readbyqxmd.com/read/28424862/laparoscopic-management-of-choledochal-cysts-is-a-keyhole-view-missing-the-big-picture
#4
REVIEW
Mark D Stringer
In recent years, numerous articles have promoted laparoscopic surgical treatment of choledochal cysts in children. Most of these reports assert that laparoscopic excision and biliary reconstruction are as safe as open surgery and achieve equivalent or better results. However, these conclusions are based on retrospective analyses with median follow-up periods that rarely exceed 5 years. Closer scrutiny of the laparoscopic literature indicates that the optimum procedure for treating type I and most type IVa choledochal cysts, namely radical excision of the extrahepatic bile ducts and reconstruction by wide hilar hepaticoenterostomy, preferably hepaticojejunostomy, is not being carried out in most cases...
April 19, 2017: Pediatric Surgery International
https://www.readbyqxmd.com/read/28417152/review-of-surgical-and-anesthetic-management-for-esophageal-atresia-with-tracheoesophageal-fistula-unilateral-pulmonary-agenesis-and-dextrocardia
#5
Rebecca M Rentea, Tolulope A Oyetunji, John Erkmann, Joshua Q Knowlton, Richard J Hendrickson
Association of unilateral severe pulmonary atresia or agenesis and esophageal atresia (EA) with or without tracheoesophageal fistula (TEF) and dextrocardia is a rare and highly lethal combination. We report a case of a full-term female infant who had EA with TEF, right lung agenesis, and dextrocardia. Repair of the fistula took place on day of life 3. We describe anesthetic and surgical concerns of this patient's case which are keys to a good operative outcome as well as follow-up for the patient.
April 17, 2017: Pediatric Surgery International
https://www.readbyqxmd.com/read/28401300/the-role-of-thymectomy-in-the-treatment-of-juvenile-myasthenia-gravis-a-systematic-review
#6
Arin L Madenci, George Z Li, Brent R Weil, David Zurakowski, Peter B Kang, Christopher B Weldon
BACKGROUND: The role of thymectomy in the treatment of juvenile myasthenia gravis (JMG) is poorly defined. The objective of this systematic review was to evaluate the effect of thymectomy on survival, disease severity, and peri-operative complications for patients with JMG. METHODS: A search of MEDLINE, EMBASE, and the Cochrane Library (1/1/2000-3/1/2016) identified all English language, human studies of thymectomy for JMG. The population was patients with JMG age ≤18 years who underwent thymectomy (comparator group was unexposed to thymectomy)...
April 11, 2017: Pediatric Surgery International
https://www.readbyqxmd.com/read/28378134/pediatric-short-bowel-syndrome-and-subsequent-development-of-inflammatory-bowel-disease-an-illustrative-case-and-literature-review
#7
Katherine J Baxter, Jahnavi K Srinivasan, Thomas R Ziegler, Tanvi Dhere, Richard R Ricketts, Megan M Durham
Short bowel syndrome (SBS) in neonates is an uncommon but highly morbid condition. As SBS survival increases, physiologic complications become more apparent. Few reports in the literature elucidate outcomes for adults with a pediatric history of SBS. We present a case report of a patient, born with complicated gastroschisis resulting in SBS at birth, who subsequently developed symptoms and pathologic changes of inflammatory bowel disease (IBD) as an adult. The patient lived from age 7, after a Bianchi intestinal lengthening procedure, to age 34 independent of parenteral nutrition (PN), but requiring hydration fluid via G-tube...
April 4, 2017: Pediatric Surgery International
https://www.readbyqxmd.com/read/28365863/robot-assisted-laparoscopic-pyeloplasty-in-the-pediatric-population-a-review-of-technique-outcomes-complications-and-special-considerations-in-infants
#8
REVIEW
William R Boysen, Mohan S Gundeti
Ureteropelvic junction obstruction is a common condition encountered by the pediatric urologist, and treated with pyeloplasty when indicated. Recent technological advancements and a shift across all surgical fields to embrace minimally invasive surgery have led to increased utilization of minimally invasive pyeloplasty. Conventional laparoscopy is a reasonable choice, but its use is limited by the technical challenges of precise suturing in a confined space and the associated considerable learning curve. Robotic technology has simplified the minimally invasive approach to pyeloplasty, offering enhanced visualization and improved dexterity with a fairly short learning curve...
April 1, 2017: Pediatric Surgery International
https://www.readbyqxmd.com/read/28364277/pediatric-choledochal-cysts-diagnosis-and-current-management
#9
REVIEW
Kevin C Soares, Seth D Goldstein, Mounes A Ghaseb, Ihab Kamel, David J Hackam, Timothy M Pawlik
Choledochal cysts are rare congenital disorders first described by Vater and Ezler in 1723. Their exact etiology remains incompletely understood; however, an anomalous pancreaticobiliary union (APBDU) and subsequent reflux of biliary contents into the biliary tree are thought to play a role. Accordingly, APBDU-associated choledochal cyst patients are significantly more likely to have evidence of hepatitis, cholangitis or pancreatitis and pathologically confirmed inflammation. In 1977, Todani and colleagues modified the original Alonso-Lej classification to include five types of CC...
March 31, 2017: Pediatric Surgery International
https://www.readbyqxmd.com/read/28353086/intraductal-papilloma-of-the-breast-in-an-11-year-old-male-patient-a-case-report
#10
Diamantis I Tsilimigras, Ioannis Ntanasis-Stathopoulos, Anargyros Bakopoulos, Dimitrios Schizas, Maria Kalfa, Irene Karyda, Dimitrios Papaioannou, Eirini Klapsinou, Charitini Salla, Theodoros N Sergentanis, Maria Moschovi
Intraductal papilloma (IP) constitutes a rare benign neoplasm among male population with only few reports on childhood patients. Herein, we describe an 11-year-old IP male patient who presented with spontaneous nipple discharge of his right breast.
March 28, 2017: Pediatric Surgery International
https://www.readbyqxmd.com/read/28293700/optimal-age-for-elective-surgery-of-asymptomatic-congenital-pulmonary-airway-malformation-a-meta-analysis
#11
REVIEW
Katrina J Sullivan, Michelle Li, Sarah Haworth, Elizabeth Chernetsova, Carolyn Wayne, Jessica Kapralik, Emily Chan, Ahmed Nasr
Controversy exists on the optimal age for elective resection of asymptomatic congenital pulmonary airway malformation. Current recommendations vary widely, highlighting the overall lack of consensus. A systematic search of Embase, MEDLINE, CINAL, and CENTRAL was conducted in January 2016. Identified citations were screening independently in duplicate and consensus was required for inclusion. Results were pooled using inverse variance fixed effects meta-analysis. Meta-analysis results indicate no statistically significant differences for complications within the 3-month and 6-month age comparison groups [odds ratio (OR) 4...
March 14, 2017: Pediatric Surgery International
https://www.readbyqxmd.com/read/28289881/modified-biliary-enteric-anastomosis-for-congenital-choledochal-cyst-clinical-and-prognostic-analysis-of-91-cases
#12
Ji Chen, Bin Jiang, Jun Yi, Lei Huang, Xinmin Si
PURPOSE: To report our experience with a modified biliary-enteric anastomosis procedure for the surgical treatment of congenital choledochal cysts. METHODS: Between January 2009 and December 2013, 91 children (19 boys, 72 girls; ages, 6-145 months) with congenital choledochal cysts were treated with our modified surgical procedure in our hospital. Of these patients, 69 had type I cysts, and 22 had type IV B cysts. The main parameters analyzed mainly included the operative time, duration of bowel recovery, resumption of diet, postoperative hospital stay, liver-function tests, postoperative complications, and prognosis...
March 13, 2017: Pediatric Surgery International
https://www.readbyqxmd.com/read/28289880/pediatric-morgagni-diaphragmatic-hernia-a-descriptive-study
#13
Jamie Golden, Wesley E Barry, Gene Jang, Nam Nguyen, David Bliss
INTRODUCTION: The Morgagni hernia (MH) accounts for 3-4% of congenital diaphragmatic hernias. There is a paucity of data regarding this rare defect. The purpose of this study is to describe the characteristics of children with MH, surgical approaches for repair, and patient outcomes. METHODS: Pediatric patients (ages 0-18) with a MH from 2002 to 2014 at a single, freestanding pediatric hospital were retrospectively reviewed. Patient presentation, demographics, operative methods and findings, and outcomes were evaluated...
March 13, 2017: Pediatric Surgery International
https://www.readbyqxmd.com/read/28271155/not-gastroschisis-or-omphalocele-or-anything-in-between-a-novel-congenital-abdominal-wall-defect
#14
Maija Cheung, Nasser Kakembo, Arlene Muzira, John Sekabira, Doruk Ozgediz
Congenital abdominal wall defects occur when normal embryonic development is interrupted and most commonly results in gastroschisis or omphalocele. Other entities, such as ruptured omphalocele, vanishing gastroschisis, and patent omphalomesenteric ducts with prolapse, have also been described and can create a confusing picture. This case of a newborn with a midline abdominal defect and a mass that was intestine-like and arose from the bowel cannot be classified, and no similar reports were found. This suggests a previously undescribed abdominal wall defect with an aberrant colonic appendage...
March 7, 2017: Pediatric Surgery International
https://www.readbyqxmd.com/read/28260193/management-and-prognosis-of-adrenocortical-tumors-in-children-can-we-find-out-an-appropriate-points-scoring-system-to-predict-prognosis
#15
Wei Ru, Min Yang, Shan Xu, Minju Li, Daxing Tang
BACKGROUND/PURPOSE: Adrenocortical tumors (ACTs) are rare in childhood. There are no recognized criteria to exactly distinguish between benign and malignant forms, or predict prognosis. The incidence of tumor varies across geographic regions or ethnicities, as well as malignant proportion. The aim of this study is to examine a single institution's experience with pediatric ACTs and to validate the prognostic value of the biologic/pathologic criteria of Wienecke. METHODS: Records of 26 pediatric ACTs between 1994 and 2016 in our center were reviewed retrospectively...
March 4, 2017: Pediatric Surgery International
https://www.readbyqxmd.com/read/28260192/polyphyllin-d-a-steroidal-saponin-in-paris-polyphylla-induces-apoptosis-and-necroptosis-cell-death-of-neuroblastoma-cells
#16
Shunsuke Watanabe, Tatuya Suzuki, Fujio Hara, Toshihiro Yasui, Naoko Uga, Atuki Naoe
PURPOSE: Neuroblastoma is a refractory pediatric malignant solid tumor. The previous studies demonstrated that Polyphyllin D, the main constituent of Paris polyphylla, a traditional Chinese medicine, exerts an anti-tumor effect on many tumors. However, its effects against neuroblastomas are unclear. METHODS: We examined the anti-tumor effect of polyphyllin D in human neuroblastoma using IMR-32 and LA-N-2 cells, which exhibit MYCN gene amplification, and NB-69 cells, which do not exhibit MYCN gene amplification...
March 4, 2017: Pediatric Surgery International
https://www.readbyqxmd.com/read/28260191/routine-use-of-chest-radiographs-in-the-post-operative-management-of-pectus-bar-removal-necessity-or-futility
#17
Ashwini Suresh Poola, Rebecca M Rentea, Katrina L Weaver, Shawn David St Peter
BACKGROUND: While there is literature on techniques for pectus bar removal, there are limited reports on post-operative management. This can include obtaining a postoperative chest radiograph (CXR) despite the minimal risk of associated intra-thoracic complications. This is a review of our experience with bar removal and lack of routine post-operative CXR. METHODS: A single institution retrospective chart review was performed from 2000 to 2015. Patients who underwent a pectus bar removal procedure were included...
March 4, 2017: Pediatric Surgery International
https://www.readbyqxmd.com/read/28251367/intestinal-perforation-secondary-to-ingested-foreign-bodies-a-single-center-experience-with-38-cases
#18
Xiao-Kun Lin, Da-Zhou Wu, Xiao-Fang Lin, Na Zheng
OBJECTIVE: The aim of this study is to report our experience with patients with intestinal perforation secondary to ingested foreign bodies (FBs) who were treated surgically at our institution. METHODS: Between 2001 and 2015, a total of 38 pediatric patients with the diagnosis of intestinal perforation secondary to FBs were retrospectively reviewed. RESULTS: The series comprised 22 males and 16 females. The average age of the patients was 1...
March 1, 2017: Pediatric Surgery International
https://www.readbyqxmd.com/read/28243740/atypical-pulmonary-sequestration-causing-respiratory-distress-in-a-2-month-old-male-infant
#19
Julio Bauza Rossi
Pulmonary sequestrations are non-functional masses of lung tissue lacking normal communication with the tracheobronchial tree and systemic-circulation-derived blood supply. The disconnection between the normal airway and pulmonary arterial supply prevents pulmonary sequestrations from participating in respiration while their aberrant circulation increases the potential for hemodynamic imbalance. Extralobar sequestrations are prenatally diagnosed, congenital lesions that may become symptomatic before or after birth, whereas intralobar sequestrations are usually identified during adulthood...
February 27, 2017: Pediatric Surgery International
https://www.readbyqxmd.com/read/28229239/same-day-discharge-after-incision-and-drainage-of-soft-tissue-abscess-in-diaper-age-children-is-safe-and-effective
#20
Ian C Glenn, Nicholas E Bruns, Domenic Craner, Alexander T Gibbons, Danial Hayek, Neil L McNinch, Oliver S Soldes, Todd A Ponsky
PURPOSE: Many pediatric centers admit patients following incision and drainage (I&D) of soft-tissue abscesses. The purpose of this study is to assess the safety and efficacy of the same-day discharge following I&D. METHODS: Retrospective review was performed of children aged 3 months-4 years who underwent operative I&D of an abscess followed by same-day discharge. Patients receiving antibiotics within 2 weeks of presentation were excluded. Treatment failure was defined as readmission or repeat procedure related to the initial abscess...
February 22, 2017: Pediatric Surgery International
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