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Pediatric Neurology

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https://www.readbyqxmd.com/read/28676246/subclinical-neuroaxonal-damage-in-patients-with-clinically-mild-encephalitis-encephalopathy-with-a-reversible-splenial-lesion
#1
LETTER
Mitsuo Motobayashi, Tetsuhiro Fukuyama, Jiu Okuno-Yuguchi, Keiko Tsukahara, Sachiko Nagaharu, Rokuro Hagimoto, Tatsuya Kinoshita, Yozo Nakazawa, Yuji Inaba
No abstract text is available yet for this article.
June 7, 2017: Pediatric Neurology
https://www.readbyqxmd.com/read/28676248/the-weekend-effect-on-morbidity-and-mortality-among-pediatric-epilepsy-admissions
#2
Timothy Wen, Daniel R Kramer, Steve Sirot, Lianne Ho, Alimohammad S Moalem, Steven Y Cen, David Millett, Christianne Heck, R Aaron Robison, William J Mack, Charles Y Liu
BACKGROUND: Pediatric epilepsy is one of the most common neurological disorders with low mortality and high morbidity, often requiring hospitalization. Weekend admissions have been shown to be associated with worse outcomes compared with their weekday counterparts. To date, no study has assessed the impact of weekend admission on clinical and quality outcomes in the pediatric epilepsy population. METHODS: Children with epilepsy were identified from the 2000, 2003, 2006, and 2009 Kids Inpatient Database...
June 2, 2017: Pediatric Neurology
https://www.readbyqxmd.com/read/28676247/a-series-of-experiences-the-2016-hower-award-lecture
#3
Harvey S Singer
No abstract text is available yet for this article.
June 2, 2017: Pediatric Neurology
https://www.readbyqxmd.com/read/28662915/a-new-patient-with-intermediate-severe-salla-disease%C3%A2-with-hypomyelination-a-literature-review-for-salla-disease
#4
Rebecca Barmherzig, Garrett Bullivant, Dawn Cordeiro, David S Sinasac, Susan Blaser, Saadet Mercimek-Mahmutoglu
BACKGROUND: Likely pathogenic variants in SLC17A5 results in allelic disorders of free sialic acid metabolism including (1) infantile free sialic acid storage disease with severe global developmental delay, coarse facial features, hepatosplenomegaly, and cardiomegaly; (2) intermediate severe Salla disease with moderate to severe global developmental delay, hypotonia, and hypomyelination with or without coarse facial features, and (3) Salla disease with normal appearance, mild cognitive dysfunction, and spasticity...
June 1, 2017: Pediatric Neurology
https://www.readbyqxmd.com/read/28676250/trends-in-antiepileptic-drug-use-in-children-and-adolescents-with-epilepsy
#5
Xinyue Liu, Paul R Carney, Regina Bussing, Richard Segal, Linda B Cottler, Almut G Winterstein
OBJECTIVE: We describe the trends in antiepileptic drug (AED) use in children and adolescents with epilepsy in the United States. METHODS: We undertook a cross-sectional study based on Medicaid Analytic eXtract data set from 26 US states. Children and adolescents aged three to 18 years with at least one year continuous Medicaid fee-for-service coverage after the second outpatient or the first inpatient diagnosis of epilepsy in each calendar year during 1999 to 2009 were included in the study; therefore, 11 cohorts were established...
May 29, 2017: Pediatric Neurology
https://www.readbyqxmd.com/read/28645465/muscle-medicine-a-small-success-worth-celebrating
#6
Stephen Mark Chrzanowski
No abstract text is available yet for this article.
May 26, 2017: Pediatric Neurology
https://www.readbyqxmd.com/read/28625466/first-pediatric-patient-with-neuromyelitis-optica-and-sj%C3%A3-gren%C3%A2-syndrome-successfully-treated-with-tocilizumab
#7
LETTER
Achille Marino, Sona Narula, Melissa A Lerman
No abstract text is available yet for this article.
May 26, 2017: Pediatric Neurology
https://www.readbyqxmd.com/read/28651978/changes-in-cerebral-oxygenation-in-preterm-infants-with-progressive-posthemorrhagic-ventricular-dilatation
#8
Michael Kochan, Jacob McPadden, William T Bass, Tushar Shah, Wendy T Brown, Gary W Tye, Turaj Vazifedan
BACKGROUND: Optimal timing of intervention in neonatal progressive posthemorrhagic hydrocephalus is often a difficult decision. Unchecked hydrocephalus can lead to irreversible brain injury through impaired perfusion, while placement of a shunt is not without long-term morbidity. The purpose of this study was to assess the use of near-infrared spectroscopy to measure changes in regional cerebral oxygen saturation as an indicator of cerebral perfusion in infants with progressive posthemorrhagic ventricular dilatation...
May 25, 2017: Pediatric Neurology
https://www.readbyqxmd.com/read/28648484/confusions-in-nomenclature-periventricular-leukomalacia-and-white-matter-injury-identical-distinct-or-overlapping
#9
Joseph J Volpe
No abstract text is available yet for this article.
May 24, 2017: Pediatric Neurology
https://www.readbyqxmd.com/read/28676245/epidemiology-clinical-presentation-and-prognosis-of-posterior-circulation-ischemic-stroke-in-children
#10
Samantha Carey, Jens Wrogemann, Frances A Booth, Mubeen F Rafay
BACKGROUND: Anterior and posterior circulation strokes are often different in terms of presentation and recurrence risk, but there are few studies that focused on posterior circulation stroke. METHODS: We performed a longitudinal retrospective study of children, birth to 18 years, with posterior circulation ischemic stroke at the Children's Hospital Winnipeg from January 1992 to December 2012. Clinical and radiological features and outcomes were collected using standardized tools...
May 19, 2017: Pediatric Neurology
https://www.readbyqxmd.com/read/28651977/dexamethasone-intravenous-immunoglobulin-and-rituximab-combination-immunotherapy-for-pediatric-opsoclonus-myoclonus-syndrome
#11
Michael R Pranzatelli, Elizabeth D Tate
BACKGROUND: Although pulse-dose dexamethasone is increasingly favored for treating pediatric opsoclonus-myoclonus syndrome (OMS), and multimodal immunotherapy is associated with improved clinical response, there have been no neuroimmunologic studies of dexamethasone-based multimodal disease-modifying therapy. METHODS: In this observational retrospective study, 19 children with OMS (with or without associated neuroblastoma) underwent multibiomarker evaluation for neuroinflammation...
May 19, 2017: Pediatric Neurology
https://www.readbyqxmd.com/read/28647131/congenital-mydriasis-with-aortic-and-cerebrovascular-disease
#12
Sandi Lam, Carolina Guimaraes, Jeremy Y Jones
No abstract text is available yet for this article.
May 19, 2017: Pediatric Neurology
https://www.readbyqxmd.com/read/28619376/early-imaging-and-adverse-neurodevelopmental-outcome-in-asphyxiated-newborns-treated-with-hypothermia
#13
Fatema Al Amrani, Saskia Kwan, Guillaume Gilbert, Christine Saint-Martin, Michael Shevell, Pia Wintermark
BACKGROUND: Brain injury can be identified as early as day two of life in asphyxiated newborns treated with hypothermia, when using diffusion magnetic resonance imaging (MRI). However, it remains unclear whether these diffusion changes can predict future neurodevelopment. This study aimed to determine whether abnormal early diffusion changes in newborns treated with hypothermia are associated with adverse neurodevelopmental outcome at age two years. METHODS: Asphyxiated newborns treated with hypothermia were enrolled prospectively...
May 19, 2017: Pediatric Neurology
https://www.readbyqxmd.com/read/28662916/patterns-of-head-computed-tomography-abnormalities-during-pediatric-extracorporeal-membrane-oxygenation-and-association-with-outcomes
#14
Kerri L LaRovere, Frederick W Vonberg, Sanjay P Prabhu, Kush Kapur, Chellamani Harini, Rogelio Garcia-Jacques, Jessica H Chao, Aliresa Akhondi-Asl, Ravi Thiagarajan, Robert C Tasker
BACKGROUND: We sought to classify type and distribution of acute infarction and hemorrhage on head computed tomography (CT) during pediatric extracorporeal membrane oxygenation (ECMO). We also analyzed the occurrence of seizures on electroencephalography and outcomes between those with and without CT abnormalities. METHODS: We conducted a single center observational study in pediatric intensive care units. The medical records of 179 children who underwent ECMO between 2009 and 2013 were reviewed...
May 18, 2017: Pediatric Neurology
https://www.readbyqxmd.com/read/28619377/cumulative-incidence-of-seizures-and-epilepsy-in-ten-year-old-children-born-before-28%C3%A2-weeks-gestation
#15
Laurie M Douglass, Timothy C Heeren, Carl E Stafstrom, William DeBassio, Elizabeth N Allred, Alan Leviton, T Michael O'Shea, Deborah Hirtz, Julie Rollins, Karl Kuban
OBJECTIVE: We evaluated the incidence of seizures and epilepsy in the first decade of life among children born extremely premature (less than 28 weeks' gestation). METHOD: In a prospective, multicenter, observational study, 889 of 966 eligible children born in 2002 to 2004 were evaluated at two and ten years for neurological morbidity. Complementing questionnaire data to determine a history of seizures, all caregivers were interviewed retrospectively for postneonatal seizures using a validated seizure screen followed by a structured clinical interview by a pediatric epileptologist...
May 18, 2017: Pediatric Neurology
https://www.readbyqxmd.com/read/28619375/a-case-of-progressive-leg-weakness
#16
Arpita Lakhotia
No abstract text is available yet for this article.
May 18, 2017: Pediatric Neurology
https://www.readbyqxmd.com/read/28583703/in-reply-death-in-pediatric-mitochondrial-disorders
#17
LETTER
Soyong Eom, Young-Mock Lee
No abstract text is available yet for this article.
May 11, 2017: Pediatric Neurology
https://www.readbyqxmd.com/read/28601240/first-episode-of-hemiplegic-migraine
#18
Stephanie Ahrens, Adam Ostendorf
No abstract text is available yet for this article.
May 10, 2017: Pediatric Neurology
https://www.readbyqxmd.com/read/28647130/fever-induced-paroxysmal-weakness-and-encephalopathy-a-new-phenotype-of-atp1a3-mutation
#19
Sho T Yano, Kenneth Silver, Richard Young, Suzanne D DeBrosse, Roseànne S Ebel, Kathryn J Swoboda, Gyula Acsadi
BACKGROUND: We identified a group of patients with ATP1A3 mutations at residue 756 who display a new phenotype, distinct from alternating hemiplegia of childhood, rapid-onset dystonia-parkinsonism, and cerebellar ataxia, areflexia, pes cavus, optic atrophy, sensorineural hearing loss syndromes. METHODS: Four patients with c.2267G>A (R756H) mutations from two families and two patients with c.2267G>T (R756L) mutations from one family are described and compared with the previously reported patients with mutations resulting in R756H and R756C protein variants...
April 29, 2017: Pediatric Neurology
https://www.readbyqxmd.com/read/28668233/incidence-and-demographics-of-pediatric-intracranial-hypertension
#20
Natalie Gillson, Charlotte Jones, Rachel E Reem, David L Rogers, Nicholas Zumberge, Shawn C Aylward
OBJECTIVE: We analyzed the incidence and demographic features of pediatric intracranial hypertension. METHODS: Inpatient and outpatient encounters of children aged 18 years or younger who were diagnosed with primary (idiopathic) or secondary intracranial hypertension between January 2010 and December 2013 were identified. Data were collected from a subspecialty clinic devoted to intracranial hypertension and the sole children's hospital in a large Midwestern city of the United States...
April 27, 2017: Pediatric Neurology
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