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Pediatric Dermatology

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https://www.readbyqxmd.com/read/28636180/characterization-of-herpes-simplex-virus-infections-seen-in-the-pediatric-dermatology-office
#1
Julia K Gittler, Euphemia W Mu, Seth J Orlow
BACKGROUND/OBJECTIVES: Atypical and severe clinical manifestations of primary and recurrent herpes simplex virus (HSV) infections may present to a pediatric dermatologist for evaluation. The purpose of this study was to characterize the clinical features of the population diagnosed with HSV referred to a pediatric dermatology office. METHODS: This retrospective case series examined patients diagnosed with HSV in a pediatric dermatology practice at an academic medical center from 2005 to 2015...
June 21, 2017: Pediatric Dermatology
https://www.readbyqxmd.com/read/28636122/hidradenitis-suppurativa-in-down-syndrome-a-case-series
#2
Issam Hamadah, Mansoor Haider, Muzamil Chisti, Yousef Binamer
BACKGROUND/OBJECTIVES: Many dermatologic and systemic diseases have been reported in association with hidradenitis suppurativa, but its association with Down syndrome is rarely mentioned in the literature. The objective of the current study was to assess the frequency of hidradenitis suppurativa in patients with Down syndrome who visited our clinic over 4 years. METHODS: We recorded the presenting complaints and dermatologic problems of patients with Down syndrome who visited our clinic from January 2011 to December 2014...
June 21, 2017: Pediatric Dermatology
https://www.readbyqxmd.com/read/28612487/anagen-effluvium-in-association-with-extracorporeal-membrane-oxygenation
#3
Lisa Cotter, Kyle Cheng, Anna Yasmine Kirkorian
Anagen effluvium (AE) is a type of alopecia with hair loss during the growth phase of a hair follicle and is most often associated with cytotoxic chemotherapy. This report describes a case of AE in a critically ill 2-year-old boy who developed cardiorespiratory failure requiring extracorporeal membranous oxygenation. We postulate that the combination of hypotension and hypoxia with subsequent reperfusion triggered an apoptotic cascade in the hair matrix, resulting in AE.
June 13, 2017: Pediatric Dermatology
https://www.readbyqxmd.com/read/28568680/mucositis-secondary-to-chlamydia-pneumoniae-infection-expanding-the-mycoplasma-pneumoniae-induced-rash-and-mucositis-concept
#4
Ander Mayor-Ibarguren, Marta Feito-Rodriguez, Jéssica González-Ramos, Teresa Del Rosal-Rabes, Francisco Javier González-Sainz, Alba Sánchez-Orta, Raul de Lucas-Laguna
The term Mycoplasma pneumoniae-induced rash and mucositis (MIRM) was recently proposed to identify the mucocutaneous condition secondary to M. pneumoniae infection that had historically been regarded among the more confusing pathologies of erythema multiforme and Stevens-Johnson syndrome. Based on a number of previous reports, these syndromes require differentiation since they have different prognoses and specific treatment requirements. We report a case of oral and genital erosions that strongly resembled MIRM without rash but were found to be secondary to a Chlamydia pneumoniae infection...
June 1, 2017: Pediatric Dermatology
https://www.readbyqxmd.com/read/28556385/atenolol-versus-propranolol-for-treatment-of-infantile-hemangiomas-during-the-proliferative-phase-a-retrospective-noninferiority-study
#5
Cheryl B Bayart, Joan E Tamburro, Allison T Vidimos, Lu Wang, Alex B Golden
BACKGROUND/OBJECTIVES: The nonselective beta-blocker propranolol is the current criterion standard for treatment of infantile hemangiomas (IHs) and the first therapy that the U.S. Food and Drug Administration has approved for the condition, but concern about adverse effects, such as bronchospasm, hypoglycemia, and sleep disturbances, has sparked interest in the use of alternative agents such as the selective β1 antagonist atenolol. Our aim was to compare the efficacy and adverse effect profiles of atenolol with those of propranolol in the treatment of IHs in a retrospective noninferiority trial...
May 28, 2017: Pediatric Dermatology
https://www.readbyqxmd.com/read/28548465/assessment-of-infantile-hemangiomas-using-a-handheld-wireless-diffuse-optical-spectroscopic-device
#6
Christopher J Fong, Maria C Garzon, Jennifer W Hoi, Hyun K Kim, Christine T Lauren, Kimberly Morel, Lauren Geller, Nina Antonov, Nicole Weitz, June Wu, Andreas H Hielscher
BACKGROUND/OBJECTIVES: Infantile hemangiomas (IHs) are vascular tumors with the potential for significant morbidity. There is a lack of validated objective tools to assess IH severity and response to treatment. Diffuse optical spectroscopy (DOS), a noninvasive, nonionizing imaging modality, can measure total hemoglobin concentration and hemoglobin oxygen saturation in tissue to assess IH vascularity and response to treatment. Our objective was to evaluate the utility of a wireless, handheld DOS system to assess IH characteristics at selected points during their clinical course...
May 26, 2017: Pediatric Dermatology
https://www.readbyqxmd.com/read/28547875/primary-cutaneous-b-cell-lymphoblastic-lymphoma-arising-from-a-long-standing-lesion-in-a-child-and-review-of-the-literature
#7
Hannah Song, Patricia Todd, Roberto Chiarle, Amy L Billett, Stephen Gellis
Precursor B-cell lymphoblastic lymphoma (B-LBL) is a rare entity and primary cutaneous B-LBL is an even more uncommon diagnosis that typically affects children. A 4-year-old boy presented with a persistent rash on his left cheek for almost 2 years and was found to have primary cutaneous B-LBL. We report this case to emphasize that B-LBL should be in the differential diagnosis for an otherwise unimpressive persistent lesion in the head and neck region and review all reported pediatric cases of primary cutaneous B-LBL without extracutaneous involvement...
May 26, 2017: Pediatric Dermatology
https://www.readbyqxmd.com/read/28547757/lymphocytic-thrombophilic-arteritis-a-possible-association-with-minocycline
#8
Colin W X Tan, Mark J A Koh
We describe a case of lymphocytic thrombophilic arteritis in a 15-year-old girl who had previously taken minocycline for a year. Cutaneous polyarteritis nodosa and lymphocytic thrombophilic arteritis share many features and may both be triggered by minocycline. There may be a long latency between drug exposure to minocycline and development of disease.
May 26, 2017: Pediatric Dermatology
https://www.readbyqxmd.com/read/28544092/fever-and-multiple-eschars-after-an-african-safari-report-of-three-cases
#9
Fátima Albízuri Prado, Alba Sánchez, Marta Feito, Ander Mayor, Ana Rodriguez, Raúl de Lucas
African tick-bite fever (ATBF), a tickborne disease endemic in rural areas of sub-Saharan Africa and the West Indies caused by Rickettsia africae, has been recognized as an emerging health problem in recent years. ATBF has been reported as the second most commonly documented etiology of fever, after malaria, in travelers who return ill from sub-Saharan Africa. Most cases reported in the literature occurred in middle-aged adults, so the incidence of ATBF in children is unclear. We report a cluster of three cases of ATBF that occurred in children ages 7 to 16 years after returning from a game-hunting safari in South Africa...
May 25, 2017: Pediatric Dermatology
https://www.readbyqxmd.com/read/28543922/molluscum-contagiosum-of-the-gluteal-cleft-observations-and-implications-for-management-in-five-children
#10
Joshua R Bakke, Sarah L Stein
Molluscum contagiosum (MC) is a common, self-limited skin infection caused by a double-stranded DNA virus of the family Poxviridae. Although the morphology of the disease is well described, MC presenting at unusual sites can exhibit atypical morphology, resulting in misdiagnosis. This observational, retrospective case series discusses the novel morphology of MC presenting in the intergluteal cleft of five children seen in the outpatient dermatology clinic of an academic medical center. We present this case series to highlight this novel presentation of MC in children and to emphasize a conservative approach to management given the sensitive location and the self-limited nature of the infection...
May 25, 2017: Pediatric Dermatology
https://www.readbyqxmd.com/read/28543852/cutaneous-granular-cell-tumors-in-children-case-series-and-review-of-the-literature
#11
Oluwatobi Olayiwola, Kristen Hook, Daniel Miller, Sheilagh Maguiness
Granular cell tumors (GCTs) are uncommon benign neoplasms thought to originate from Schwann cells. They most commonly present in adults as papules or nodules on mucosal sites. The clinical spectrum of GCT in children is not well delineated, although mucosal and cutaneous presentations have been reported. We present three children with cutaneous GCTs and review the literature in an attempt to further characterize this rare pediatric neoplasm.
May 25, 2017: Pediatric Dermatology
https://www.readbyqxmd.com/read/28543846/congenital-herpes-simplex-virus-type-1-infection-mimicking-congenital-erosive-and-vesicular-dermatosis-possible-pathogenic-insights
#12
Andrew W Swarbrick, Christopher C Blyth, Anne R Halbert
Congenital erosive and vesicular dermatosis (CEVD) is a rare entity of unknown etiology. We report a case of congenital herpes simplex virus (HSV) type 1 infection that healed with reticulated and supple scarring, similar to that seen in CEVD. Twenty percent of previously reported cases of CEVD had recurrent HSV infection throughout the first year of life. We postulate that at least some previous cases of CEVD may have been due to undiagnosed congenital HSV infection.
May 25, 2017: Pediatric Dermatology
https://www.readbyqxmd.com/read/28543769/perceptions-and-practices-regarding-atopic-dermatitis-a-survey
#13
Katherine R Grey, Kristen P Hook, Ingrid C Polcari, Sheilagh M Maguiness
Parents (N = 392) completed a survey at the Minnesota State Fair in August and September 2015 addressing knowledge regarding the pathogenesis of atopic dermatitis (AD), basic skin care practices, and the perceived role of infection and food allergies in AD. Of participating parents, 82% identified food allergy or sensitivity in AD pathogenesis, whereas only 42% identified bacterial infection as an important factor in AD severity. Participants most often received education on skin health from their pediatrician (49%), followed by Internet-based sources (23%), rather than a dermatologist or pediatric dermatologist...
May 25, 2017: Pediatric Dermatology
https://www.readbyqxmd.com/read/28543755/comparison-of-two-formulations-of-topical-timolol-for-the-treatment-of-infantile-hemangiomas
#14
Michelle Si Ying Ng, Yong-Kwang Tay, Shanna Shan-Yi Ng, Alice Yee Wah Foong, Mark Jean-Aan Koh
This report compares the efficacy of timolol maleate 0.5% eyedrops (TM) with that of timolol maleate 0.5% ophthalmic gel-forming solution in the treatment of infantile hemangiomas (IHs). Sixty-six patients undergoing treatment with topical timolol were retrospectively reviewed; our results revealed similar therapeutic efficacies for both types of timolol formulations. Early treatment initiation (<3 mos) and superficial lesions correlated with better treatment response. TM eyedrops may be a more cost effective, equally efficacious modality of treatment for IHs...
May 25, 2017: Pediatric Dermatology
https://www.readbyqxmd.com/read/28543716/an-atopic-dermatitis-management-algorithm-for-primary-care-providers-and-assessment-of-its-usefulness-as-a-clinical-tool
#15
Maria E Miyar, Megan Brown, Karina L Vivar, Kimberly Jablon, Christy Boscardin, Moise L Levy, Joyce M Teng, Erin F Mathes
BACKGROUND/OBJECTIVES: There is a lack of primary care provider (PCP) understanding of atopic dermatitis (AD) treatments and topical steroid use. We designed an AD management algorithm for pediatric PCPs. We hypothesized that the algorithm would improve pediatric PCPs' knowledge of AD diagnosis and management. METHODS: Pediatric primary care resident and attending physicians at three residency programs were invited to participate in an electronic AD algorithm survey that contained demographic and 19 knowledge-based questions...
May 25, 2017: Pediatric Dermatology
https://www.readbyqxmd.com/read/28543629/epidemiology-and-predisposing-factors-for-erythema-toxicum-neonatorum-and-transient-neonatal-pustular-a-multicenter-study
#16
Flávia Pereira Reginatto, Fernanda Mello Muller, Juliano Peruzzo, Tania Ferreira Cestari
BACKGROUND/OBJECTIVES: Erythema toxicum neonatorum (ETN) and transient neonatal pustular melanosis (TNPM) are benign pustular skin conditions that are relatively common in newborns, but the predisposing factors for these conditions are unknown. Our goal was to verify the prevalence of ETN and TNPM and their predisposing factors in a large sample of neonates. METHODS: In this prospective 1-year multicenter study, 2,831 neonates (age ≤72 hours) born in southern Brazil were randomized to undergo skin examination by a dermatologist...
May 25, 2017: Pediatric Dermatology
https://www.readbyqxmd.com/read/28544234/clinical-microscopic-and-ultrastructural-findings-in-a-case-of-short-anagen-syndrome
#17
Jose M Martin, Encarnacion Montesinos, Sara Sanchez, Catalina Torres, Dolores Ramon
Short anagen syndrome is an uncommon and recently described disease characterized by many telogen hairs and short maximum hair length. We report here the case of a 3-year-old girl whose short, sparse, fine hair since birth was consistent with short anagen syndrome. X-ray microanalysis demonstrated normal composition of the main bioelements of her hairs.
May 23, 2017: Pediatric Dermatology
https://www.readbyqxmd.com/read/28544027/a-novel-vps33b-mutation-in-a-patient-with-arthrogryposis-renal-dysfunction-cholestasis-syndrome
#18
Amanda T Moon, Theresa Christensen, Jenna L Streicher, Leslie Castelo-Soccio
We report a case of arthrogryposis-renal dysfunction-cholestasis (ARC) syndrome in a girl with a novel VPS33B mutation. To our knowledge, this is the first reported case of ARC syndrome in the United States.
May 23, 2017: Pediatric Dermatology
https://www.readbyqxmd.com/read/28543809/practice-patterns-of-dermatologists-in-the-pediatric-contact-dermatitis-registry
#19
Sharon E Jacob, Michael B Lipp, Eric Suh, Alina Goldenberg
BACKGROUND/OBJECTIVES: U.S. adults and children are equally likely to have allergic contact dermatitis. Historically the narrow geographic location of data-reporting providers has quantitatively and qualitatively limited the pediatric contact dermatitis data. The Pediatric Contact Dermatitis Registry was used to evaluate self-identified pediatric patch test providers within the United States with regard to demographic characteristics, geographic location, and practice patterns. METHODS: A wide range of U...
May 23, 2017: Pediatric Dermatology
https://www.readbyqxmd.com/read/28543792/lichenoid-drug-eruption-with-prominent-nail-changes-due-to-leflunomide-in-a-12-year-old-child
#20
Caitlin May, Philip Fleckman, Heather A Brandling-Bennett, Bonnie Cole, Robert Sidbury
We present the case of a 12-year-old-girl who developed lichenoid dermatitis approximately 1 year after starting leflunomide for juvenile idiopathic arthritis. The eruption resolved promptly with discontinuation of the suspected culprit agent, supportive of a lichenoid drug eruption, but she subsequently developed markedly dystrophic nails with lichen planus-like features. A biopsy of her cutaneous findings at the time of initial presentation demonstrated lichenoid dermatitis, and a nail matrix biopsy was deferred given clinical correlation...
May 23, 2017: Pediatric Dermatology
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