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Pediatric Cardiology

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https://www.readbyqxmd.com/read/29147800/the-pediatric-heart-failure-workforce-an-international-multicenter-survey
#1
Scott R Auerbach, Melanie D Everitt, Ryan J Butts, David N Rosenthal, Yuk M Law
Our objective was to understand the scope of pediatric heart failure (HF) and the current staffing environment of HF programs. An online survey was distributed to members of the Pediatric Heart Transplant Study and the Pediatric Council of the International Society for Heart and Lung Transplantation. All participants received the primary 23-question survey. Additionally, HF program directors received a 32-question supplemental survey. Of 235 invitations sent, there were 69 (29%) primary surveys and 34 program director surveys completed (24 U...
November 17, 2017: Pediatric Cardiology
https://www.readbyqxmd.com/read/29147786/risk-factors-for-development-of-ectopic-atrial-tachycardia-in-post-operative-congenital-heart-disease
#2
Bradley C Clark, John T Berger, Charles I Berul, Richard A Jonas, Jonathan R Kaltman, Julianne Lapsa, Dilip S Nath, Elizabeth D Sherwin, Pranava Sinha, David Zurakowski, Jeffrey P Moak
Ectopic atrial tachycardia (EAT) is common in surgically repaired congenital heart disease (CHD) and carries the potential for significant hemodynamic compromise. Our objective was to determine the incidence, and risk factors of EAT after CHD surgery. Prospective study of patients that underwent surgery for CHD from February to October 2016 was performed. Demographic, perioperative and electrophysiologic data were collected. Sustained EAT (> 30 s) was documented by telemetry or electrocardiogram and confirmed by a pediatric electrophysiologist...
November 17, 2017: Pediatric Cardiology
https://www.readbyqxmd.com/read/29138879/predictive-factors-for-patients-undergoing-asd-device-occlusion-who-crossover-to-surgery
#3
Venkatachalam Mulukutla, Athar M Qureshi, Ricardo Pignatelli, Frank F Ing
The aim of this study was to define characteristics of those patients who are referred for device closure of an Atrial septal defect (ASD), but identified to "crossover" surgery. All patients who underwent surgical and device (Amplatzer or Helex occluder) closures of secundum ASDs from 2001 to 2010 were reviewed and organized into three groups: surgical closure, device closure, and "crossover" group. 369 patients underwent ASD closure (265 device, 104 surgical). 42 of the 265 patients referred for device closure "crossed over" to the surgical group at various stages of the catheterization procedure...
November 15, 2017: Pediatric Cardiology
https://www.readbyqxmd.com/read/29138878/higher-cost-of-hospitalizations-for-non-cardiac-diagnoses-in-adults-with-congenital-heart-disease
#4
Michael D Seckeler, Ian D Thomas, Jennifer Andrews, Omar Meziab, Tabitha Moe, Elissa Heller, Scott E Klewer
Adults with congenital heart disease (CHD) are a rapidly increasing population and their impact on healthcare resources is not fully understood. The purpose of this study was to describe the costs of hospitalizations for non-cardiac disease for adults with CHD. We conducted a retrospective review of hospital discharge data from the University HealthSystem Consortium Clinical Data Base/Resource Manager from January 2011 through December 2013. Patients were ≥ 18 years old at admission with any ICD-9 code for moderate or high severity CHD; cardiac surgical admissions were excluded...
November 15, 2017: Pediatric Cardiology
https://www.readbyqxmd.com/read/29134238/a-comparison-of-anterograde-versus-retrograde-approaches-for-neonatal-balloon-aortic-valvuloplasty
#5
Namrita Mozumdar, Edmund Burke, Melissa Schweizer, Matthew J Gillespie, Yoav Dori, Hari K Narayan, Jonathan J Rome, Andrew C Glatz
In neonates requiring balloon aortic valvuloplasty, both anterograde and retrograde approaches are feasible. A recent comparison of these two approaches is lacking. A retrospective cohort study of neonates at a single center undergoing BAV from 9/00 to 7/14 was performed. Records were reviewed including pre- and post-intervention echocardiograms and catheterization data. Comparisons of acute efficacy and procedural safety were made based on type of approach utilized. Forty-two neonates underwent BAV. Eleven cases utilized exclusively an anterograde approach, while 31 included a retrograde approach (including 4 with both approaches used)...
November 13, 2017: Pediatric Cardiology
https://www.readbyqxmd.com/read/29119215/surgical-ligation-versus-percutaneous-closure-of-patent-ductus-arteriosus-in-very-low-weight-preterm-infants-which-are-the-real-benefits-of-the-percutaneous-approach
#6
A Rodríguez Ogando, I Planelles Asensio, A Rodríguez Sánchez de la Blanca, F Ballesteros Tejerizo, M Sánchez Luna, J M Gil Jaurena, C Medrano López, J L Zunzunegui Martínez
Percutaneous treatment of patent ductus arteriosus (PDA) in extreme premature infants is technically difficult, and therefore, often not consider as an alternative to surgery. The main objective of our work was to compare respiratory status prior and post ductal closure and morbi-mortality, in our series of preterm infants with percutaneous PDA closure versus surgical ligation in the same time-period. Retrospective review of all premature infants submitted to percutaneous and surgical PDA closure from January 2011 to December 2016...
November 8, 2017: Pediatric Cardiology
https://www.readbyqxmd.com/read/29119214/safety-and-efficacy-of-radiofrequency-catheter-ablation-for-tachyarrhythmia-in-children-weighing-less-than-10%C3%A2-kg
#7
Noriyasu Ozaki, Yoshihide Nakamura, Tsugutoshi Suzuki, Jun Yoshimoto, Keiko Toyohara, Hitoo Fukuhara, Hiroshi Katayama, Kanta Kishi, Yutaka Odanaka, Hiroshi Tamai
An increasing number of children are undergoing radiofrequency catheter ablation (RFCA) for tachyarrhythmia. However, infants and toddlers undergoing RFCA are often resistant to medication or need to eliminate arrhythmia substrate, and the risks of RFCA complications are still high in infants and toddlers. From April 2008 and December 2016, 285 children who underwent radiofrequency catheter ablation (RFCA) were stratified according to body weight (group A, less than 10 kg, n = 22; group B, over 10 kg, n = 263) and the clinical features of RFCA were retrospectively reviewed in these groups...
November 8, 2017: Pediatric Cardiology
https://www.readbyqxmd.com/read/29098353/pediatric-heart-transplantation-transitioning-to-adult-care-transit-baseline-findings
#8
Kathleen L Grady, Kathleen Van't Hof, Adin-Cristian Andrei, Tamara Shankel, Richard Chinnock, Shelley Miyamoto, Amrut V Ambardekar, Allen Anderson, Linda Addonizio, Farhana Latif, Debra Lefkowitz, Lee Goldberg, Seth A Hollander, Michael Pham, Jill Weissberg-Benchell, Nichole Cool, Clyde Yancy, Elfriede Pahl
Young adult solid organ transplant recipients who transfer from pediatric to adult care experience poor outcomes related to decreased adherence to the medical regimen. Our pilot trial for young adults who had heart transplant (HT) who transfer to adult care tests an intervention focused on increasing HT knowledge, self-management and self-advocacy skills, and enhancing support, as compared to usual care. We report baseline findings between groups regarding (1) patient-level outcomes and (2) components of the intervention...
November 3, 2017: Pediatric Cardiology
https://www.readbyqxmd.com/read/29098351/the-roles-of-genetic-factors-in-kawasaki-disease-a-systematic-review-and-meta-analysis-of-genetic-association-studies
#9
REVIEW
Xiaochuan Xie, Xiaohan Shi, Meilin Liu
This systematic review and meta-analysis aimed to better elucidate the roles of genetic factors in Kawasaki disease (KD), and determine the potential genetic biomarkers of KD. The systematic literature search of PubMed, Medline, Embase, Web of Science and CNKI identified 164 eligible studies. The qualitative synthesis revealed that 62 genes may be correlated with the susceptibility to KD, and 47 genes may be associated with the incidence of coronary artery lesions (CALs) in KD. A total of 53 polymorphisms in 34 genes were investigated in further quantitative synthesis...
November 2, 2017: Pediatric Cardiology
https://www.readbyqxmd.com/read/29098350/reintervention-burden-and-vessel-growth-after-surgical-reimplantation-of-a-pulmonary-artery-during-childhood
#10
Stephan J Wu, Tacy Downing, Christopher Mascio, Matthew J Gillespie, Yoav Dori, Jonathan J Rome, Andrew C Glatz
Children requiring reimplantation of a branch pulmonary artery (PA) are at risk for postoperative stenosis and impaired growth of the reimplanted PA. Outcomes and risk factors for reintervention and impaired growth are incompletely described. We reviewed data on patients who underwent reimplantation of a branch PA between 1/1/99 and 5/1/15 at a single center. The primary outcome was reintervention to treat postoperative stenosis. The secondary outcome was "catch-up" growth (faster diameter growth of the affected PA compared with the unaffected PA from the preoperative to follow-up measurements...
November 2, 2017: Pediatric Cardiology
https://www.readbyqxmd.com/read/29098349/vortex-flow-in-the-right-atrium-surrogates-supraventricular-arrhythmia-and-thrombus-after-atriopulmonary-connection-type-fontan-operation-vortex-flow-analysis-using-conventional-cine-magnetic-resonance-imaging
#11
Yumi Shiina, Kei Inai, Tatsunori Takahashi, Yamato Shimomiya, Umiko Ishizaki, Kenji Fukushima, Michinobu Nagao
We developed a novel imaging technique, designated as vortex flow (VF) mapping, which presents a vortex flow visually on conventional two-dimensional (2D) cine MRI. Using it, we assessed circumferential VF patterns and influences on RA thrombus and supraventricular tachycardia (SVT) in AP connection-type Fontan circulation. Retrospectively, we enrolled 27 consecutive patients (25.1 ± 9.2 years) and 7 age-matched controls who underwent cardiac MRI. Conventional cine images acquired using a 1.5-Tesla scanner were scanned for axial and coronal cross section of the RA...
November 2, 2017: Pediatric Cardiology
https://www.readbyqxmd.com/read/29094192/changes-in-bi-ventricular-function-after-hematopoietic-stem-cell-transplant-as-assessed-by-speckle-tracking-echocardiography
#12
Stuart Covi, Yaddanapudi Ravindranath, Ahmad Farooqi, Sureyya Savasan, Roland Chu, Sanjeev Aggarwal
Hematopoietic stem cell transplant (HSCT) is a therapeutic option for patients with sickle cell disease (SCD) and severe acquired aplastic anemia (SAA). HSCT may have beneficial effects on ventricular function in damaged myocardium. We hypothesized improvement in ventricular performance and pulmonary hypertension following HSCT with strain echocardiography in SCD and SAA. Echocardiographic strain and other standard functional data were obtained via retrospective cohort analysis of patients (n = 23) with SCD and SAA who underwent HSCT and were followed at a single center between 2000 and 2014...
November 1, 2017: Pediatric Cardiology
https://www.readbyqxmd.com/read/29090353/rapid-improvement-of-pulmonary-functions-in-children-after-transcatheter-closure-of-an-atrial-septal-defect
#13
Serkan F Çelik, Cemşit Karakurt, Nurdan Yıldırım Acar, Elif Çelik
There are very few studies in the literature on respiratory system functions and complications of children with an atrial septal defect (ASD). The aim of this study is to investigate the pulmonary functions and pulmonary complications before and after transcatheter closure in children with an ASD. In this study, pulmonary function test parameters of 30 ASD patients between 5 and 18 years of age who were eligible to be treated by transcatheter ASD closure were compared with 30 healthy children. The patients undergoing transcatheter ASD closure received pulmonary function tests (PFT) at baseline (1 day before ASD closure), and 3 months after the procedure...
October 31, 2017: Pediatric Cardiology
https://www.readbyqxmd.com/read/29090352/oxidation-reduction-potential-orp-is-predictive-of-complications-following-pediatric-cardiac-surgery
#14
Amy E Schmidt, Emily Gore, Kelly F Henrichs, Grace Conley, Charles Dorsey, Kimberly B Bjugstad, Majed A Refaai, Neil Blumberg, Jill M Cholette
Oxidation reduction potential (ORP) or Redox is the ratio of activity between oxidizers and reducers. Oxidative stress (OS) can cause cellular injury and death, and is important in the regulation of immune response to injury or disease. In the present study, we investigated changes in the redox system as a function of cardiopulmonary bypass (CPB) in pediatric patients. 664 plasma samples were collected from 162 pediatric patients having cardiac surgery of various CPB times. Lower ORP values at 12 h post-CPB were associated with poor survival rate (mean ± SD 167 ± 20 vs...
October 31, 2017: Pediatric Cardiology
https://www.readbyqxmd.com/read/29090351/usefulness-of-routine-coronary-ct-angiography-in-patients-with-transposition-of-the-great-arteries-after-an-arterial-switch-operation
#15
Konrad Szymczyk, Maciej Moll, Katarzyna Sobczak-Budlewska, Jadwiga A Moll, Ludomir Stefańczyk, Piotr Grzelak, Jacek J Moll, Krzysztof W Michalak
Coronary complications in patients with transposition of the great arteries (TGA) after an arterial switch operation (ASO) are relatively rare, but of all the possible postoperative adverse events, they are potentially the most dangerous. The fate of the coronary arteries, which are transplanted during the neonatal ASO, remains uncertain. There is also no consensus regarding their postoperative evaluation, especially in asymptomatic patients. The aim of this study was to present the early results of routinely performed coronary computed tomography angiography (CCTA) in asymptomatic adolescents and young adults with TGA after an ASO...
October 31, 2017: Pediatric Cardiology
https://www.readbyqxmd.com/read/29090350/longer-ischemic-time-is-associated-with-increased-ventricular-stiffness-as-measured-by-pressure-volume-loop-analysis-in-pediatric-heart-transplant-recipients
#16
Luke W Schroeder, Shahryar M Chowdhury, Ali L Burnette, Minoo N Kavarana, G Hamilton Baker, Andrew J Savage, Andrew M Atz, Ryan J Butts
BACKGROUND: The purpose of this study was to investigate the associations between clinical factors and cardiac function as measured by pressure-volume loops (PVLs) in a pediatric heart transplant cohort. METHODS: Patients (age < 20 years) who underwent heart transplantation presenting for a clinically indicated catheterization were enrolled. PVLs were recorded using microconductance catheters (CD Leycom(®), Zoetermeer, Netherlands). Demographic data, serum B-type natriuretic peptide (BNP), time from transplant, ischemic time, presence of transplant coronary artery disease, donor-specific antibodies, and history of rejection were recorded at the time of catheterization...
October 31, 2017: Pediatric Cardiology
https://www.readbyqxmd.com/read/29086807/characteristics-of-non-postoperative-pediatric-pericardial-effusion-a-multicenter-retrospective-cohort-study-from-the-pediatric-health-information-system-phis
#17
Elijah H Bolin, Xinyu Tang, Sean M Lang, Joshua A Daily, R Thomas Collins
Little is known about the causes and risks of non-postoperative pericardial effusion (PCE) in pediatric patients. We sought to assess the diagnoses most frequently associated with admissions for PCE, and to determine if certain conditions were associated with higher in-hospital mortality and rates of readmission. Nationally distributed data from 44 pediatric hospitals in the 2004-2015 Pediatric Health Information System database were used to identify patients with hospital admissions for International Classification of Disease, Ninth Revision (ICD-9) codes for PCE and/or cardiac tamponade...
October 31, 2017: Pediatric Cardiology
https://www.readbyqxmd.com/read/29079985/preserved-cardiac-blood-supply-workload-balance-in-pediatric-patients-after-aortic-arch-repair
#18
Tomoaki Murakami, Atsuhito Takeda
One of the most important problems in patients with aortic coarctation after aortic arch repair is future cardiovascular disease. We have previously reported that the enhancement of aortic pressure wave reflection in patients could be one of the causes of future cardiovascular diseases, because it results in an increase of the left ventricular workload and is disadvantageous for coronary circulation. Seventeen patients who had undergone aortic arch repair without pressure gradient in their aortic arch were enrolled...
October 27, 2017: Pediatric Cardiology
https://www.readbyqxmd.com/read/29071373/longitudinal-myocardial-deformation-does-not-predict-single-ventricle-ejection-fraction-assessed-by-cardiac-magnetic-resonance-imaging-in-children-with-a-total-cavopulmonary-connection
#19
L P Koopman, L M Geerdink, S S M Bossers, N Duppen, I M Kuipers, A D Ten Harkel, G van Iperen, G Weijers, C de Korte, W A Helbing, L Kapusta
Survival of children with single ventricle heart defects after the total cavopulmonary connection (TCPC) has improved, but impaired cardiac function remains a major cause of morbidity and mortality. Cardiac magnetic resonance imaging (cMRI) is the gold standard in assessing single ventricle volume and function, but high costs and limited availability hamper its routine use. A cheaper and more available alternative is echocardiography. Myocardial function can be studied in more detail using speckle tracking echocardiography (STE)...
October 25, 2017: Pediatric Cardiology
https://www.readbyqxmd.com/read/29063953/magnetic-resonance-myocardial-perfusion-imaging-safety-and-indications-in-pediatrics-and-young-adults
#20
David M Biko, R Thomas Collins, Sara L Partington, Matthew Harris, Kevin K Whitehead, Marc S Keller, Mark A Fogel
The purpose of this study was to assess the safety and indications for cardiac magnetic resonance (CMR) with myocardial perfusion imaging (MPI) in a cohort of children and young adults. A retrospective review of 178 children and young adults who underwent CMR with MPI was performed. Studies were categorized based on study protocols as MPI with resting perfusion only, adenosine stress MPI, exercise-induced stress MPI, and MPI for cardiac mass diagnosis. Relevant clinical history, exam indications, and adverse reactions following gadolinium-based contrast agent and adenosine administration were recorded...
October 24, 2017: Pediatric Cardiology
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