journal
MENU ▼
Read by QxMD icon Read
search

Pediatric Blood & Cancer

journal
https://www.readbyqxmd.com/read/28087884/the-role-of-immunoglobulin-prophylaxis-for-prevention-of-cytomegalovirus-infection-in-pediatric-hematopoietic-stem-cell-transplantation-recipients
#1
Gal Goldstein, Tal Frenkel Rutenberg, Sarina Levy Mendelovich, Daphna Hutt, Michal Teperberg Oikawa, Amos Toren, Bella Bielorai
BACKGROUND: Following cessation of intravenous immunoglobulin (IVIg) administration for allogeneic hematopoietic stem cell transplantation (HSCT) recipients at our unit, we observed a sharp decline in the incidence of cytomegalovirus (CMV) infection. PROCEDURE: We conducted a retrospective study of the role of IVIg in the prevention of CMV infection in children and young adults who underwent HSCT from matched related donor. RESULTS: We included 109 patients (IVIg+/IVIg- ratio 82/27)...
January 14, 2017: Pediatric Blood & Cancer
https://www.readbyqxmd.com/read/28084680/rapid-and-fulminant-leptomeningeal-spread-following-radiotherapy-in-diffuse-intrinsic-pontine-glioma
#2
Christopher L Tinkle, Brent A Orr, John T Lucas, Paul Klimo, Zoltan Patay, Suzanne J Baker, Alberto Broniscer, Ibrahim Qaddoumi
A 4-year-old male presented with rapid-onset cranial nerve palsy and ataxia. Brain magnetic resonance imaging (MRI) revealed a pontine mass lesion with discordant conventional and advanced imaging. A stereotactic core biopsy revealed glioblastoma with immunostaining suggestive of histone H3K27M and TP53 mutation, consistent with diffuse intrinsic pontine glioma. MRI 3 months after radiotherapy revealed extensive new leptomeningeal metastatic disease involving both the supra- and infratentorial brain, as well as the imaged portion of the spine...
January 13, 2017: Pediatric Blood & Cancer
https://www.readbyqxmd.com/read/28084677/location-location-location-does-it-matter-for-childhood-cancer-survivors-considering-pediatric-vs-adult-care-settings
#3
Megan V Hilgers, Megan E Slater, Karim Thomas Sadak
No abstract text is available yet for this article.
January 13, 2017: Pediatric Blood & Cancer
https://www.readbyqxmd.com/read/28084675/transient-juvenile-myelomonocytic-leukemia-in-the-setting-of-ptpn11-mutation-and-noonan-syndrome-with-secondary-development-of-monosomy-7
#4
Katrina O'Halloran, A Kim Ritchey, Miroslav Djokic, Erika Friehling
Juvenile myelomonocytic leukemia (JMML) is a rare childhood neoplasm with poor prognosis except in the setting of Noonan syndrome, where prognosis is generally favorable. We present the case of a child with JMML in the setting of germline PTPN11 mutation and Noonan syndrome with suspected secondary development of monosomy 7 in the bone marrow. Diagnosed shortly after birth, she has been managed with active surveillance alone. Myeloblast percentages initially fluctuated; however, bone marrow biopsy at 4 years of age showed spontaneous remission despite persistence of the monosomy 7 clone, supporting a cautious approach in similar cases...
January 13, 2017: Pediatric Blood & Cancer
https://www.readbyqxmd.com/read/28084041/salvage-therapy-for-children-with-relapsed-or-refractory-philadelphia-chromosome-positive-acute-lymphoblastic-leukemia
#5
Yuichi Kodama, Atsushi Manabe, Hirohide Kawasaki, Itaru Kato, Keisuke Kato, Atsushi Sato, Kimikazu Matsumoto, Motohiro Kato, Hidefumi Hiramatsu, Hideki Sano, Takashi Kaneko, Megumi Oda, Akiko M Saito, Souichi Adachi, Keizo Horibe, Shuki Mizutani, Eiichi Ishii, Hiroyuki Shimada
BACKGROUND: In the tyrosine kinase inhibitor (TKI) era, outcomes after salvage therapy for relapsed or refractory Philadelphia chromosome-positive (Ph+) acute lymphoblastic leukemia (ALL) remain unclear. PROCEDURE: The clinical courses of 19 patients with relapse (n = 13) or induction failure (n = 6) in the Japanese Pediatric Leukemia/Lymphoma Study Group Ph+ ALL04 study were retrospectively reviewed. RESULTS: Fifteen male and four female patients had a median age of 8 (range 4-15) years at relapse or induction failure...
January 13, 2017: Pediatric Blood & Cancer
https://www.readbyqxmd.com/read/28083994/on-paranoid-parents
#6
Pan Pantziarka
No abstract text is available yet for this article.
January 13, 2017: Pediatric Blood & Cancer
https://www.readbyqxmd.com/read/28074636/comment-on-juvenile-granulosa-cell-ovarian-tumor-in-a-child-with-beckwith-wiedemann-syndrome
#7
LETTER
Frederic Brioude, Irène Netchine
No abstract text is available yet for this article.
January 11, 2017: Pediatric Blood & Cancer
https://www.readbyqxmd.com/read/28074607/the-use-of-intravenous-pentamidine-for-the-prophylaxis-of-pneumocystis-pneumonia-in-pediatric-patients
#8
Matthijs D Kruizinga, Dorine Bresters, Frans J Smiers, Arjan C Lankester, Robbert G M Bredius
Pneumocystis jiroveci pneumonia was common in the immunocompromised host before the widespread use of prophylaxis. When trimethoprim-sulfamethoxazole is not tolerated, prophylaxis with intravenous pentamidine (IVP) may be initiated. We performed a retrospective analysis of all pediatric patients who received IVP regarding efficacy, safety, and reason for initiation. Of 106 patients included in our analysis, one patient tested positive for Pneumocystis DNA. Adverse events were reported in 18% of IVP courses, and main reason for initiation was cytopenia (59%)...
January 11, 2017: Pediatric Blood & Cancer
https://www.readbyqxmd.com/read/28074592/birthweight-and-site-of-osteosarcoma-development
#9
LETTER
Brandon J Diessner, Logan G Spector
No abstract text is available yet for this article.
January 11, 2017: Pediatric Blood & Cancer
https://www.readbyqxmd.com/read/28074551/detection-of-a-clone-specific-gata1-mutation-to-monitor-treatment-response-and-involvement-of-a-monozygotic-twin-in-myeloid-leukemia-of-down-syndrome
#10
LETTER
Salah Ali, Kaleem Ashraf, John Chen, Johann K Hitzler
No abstract text is available yet for this article.
January 11, 2017: Pediatric Blood & Cancer
https://www.readbyqxmd.com/read/28074537/neuroblastoma-causes-alterations-of-the-intestinal-microbiome-gut-hormones-inflammatory-cytokines-and-bile-acid-composition
#11
Christoph Castellani, Georg Singer, Margarita Kaiser, Thomas Kaiser, Jianfeng Huang, Daniela Sperl, Karl Kashofer, Guenter Fauler, Barbara Guertl-Lackner, Gerald Höfler, Holger Till
OBJECTIVE: To assess the effect of neuroblastoma (NB) on the intestinal microbiome, metabolism, and inflammatory parameters in a murine model. MATERIALS AND METHODS: Athymic Hsd:Fox1nu mice received subperitoneal implantation of human NB cells (MHH-NB11) (tumor group, TG) or culture medium (sham group). Following 10 weeks of tumor growth, all animals were sacrificed to collect total white adipose tissue (WAT). Luminex assays were performed for gut hormone and inflammation marker analysis...
January 11, 2017: Pediatric Blood & Cancer
https://www.readbyqxmd.com/read/28074531/antibiotic-use-during-infectious-episodes-in-the-first-6-months-of-anticancer-treatment-a-swedish-cohort-study-of-children-aged-7-16-years
#12
M Af Sandeberg, E Johansson, L Wettergren, O Björk, O Hertting, A Nilsson
BACKGROUND: Children undergoing cancer therapy are at risk for infectious complications that require hospitalization and antimicrobial therapy. Host factors such as age and underlying disease may predict the risk of severe infections in these children. To describe the increased morbidity due to infections in children with cancer, we characterized the antibiotic use during the infectious complications in a national cohort of children 7-16 years of age with cancer. PROCEDURE: Data on infectious complications were prospectively collected from the medical records of all newly diagnosed children with cancer, aged 7-16 years, in Sweden between 2004 and 2006...
January 11, 2017: Pediatric Blood & Cancer
https://www.readbyqxmd.com/read/28067012/venous-thromboembolism-in-pediatric-trauma-patients-ten-year-experience-and-long-term-follow-up-in-a-tertiary-care-center
#13
Christine M Leeper, Madhav Vissa, James D Cooper, Lynn M Malec, Barbara A Gaines
BACKGROUND: Pediatric trauma patients are at high risk for development of venous thromboembolism (VTE). Our objective is to describe incidence, risk factors, and timing of development of VTE, anticoagulation complications, and long-term VTE outcomes in a critically injured pediatric population. PROCEDURE: We did a retrospective review of pediatric (0-17 years) trauma admissions to intensive care unit from 2005 to 2014. Our center employs VTE screening and prevention protocols for high-risk patients based on hypercoagulable history, age, injuries, and medical interventions...
January 9, 2017: Pediatric Blood & Cancer
https://www.readbyqxmd.com/read/28066994/a-case-of-gata2-related-myelodysplastic-syndrome-with-unbalanced-translocation-der-1-7-q10-p10
#14
LETTER
Takashi Kurata, Tomonari Shigemura, Hideki Muramatsu, Yusuke Okuno, Yozo Nakazawa
No abstract text is available yet for this article.
January 9, 2017: Pediatric Blood & Cancer
https://www.readbyqxmd.com/read/28066990/management-of-adrenal-masses-in-patients-with-beckwith-wiedemann-syndrome
#15
Suzanne P MacFarland, Sogol Mostoufi-Moab, Kristin Zelley, Peter A Mattei, Lisa J States, Tricia R Bhatti, Kelly A Duffy, Garrett M Brodeur, Jennifer M Kalish
Beckwith-Wiedemann syndrome (BWS) is a genetic overgrowth and cancer predisposition syndrome, associated with both benign and malignant adrenal findings. Literature review and an institutional case series elucidate the wide spectrum of adrenal findings in BWS patients. The altered expression of the 11p15 region is likely related to adrenal gland hyperplasia and growth dysregulation. Given the absence of guidelines for managing adrenal findings in BWS, we propose a systematic approach to adrenal findings in BWS patients, to allow for maximum detection of potentially malignant pathology without posing additional risk to patients...
January 9, 2017: Pediatric Blood & Cancer
https://www.readbyqxmd.com/read/28066975/targeting-brak-mek-mtor-and-now-akt-in-histiocytosis-the-ongoing-revolution-of-therapies-in-orphan-diseases
#16
Julien Haroche
No abstract text is available yet for this article.
January 9, 2017: Pediatric Blood & Cancer
https://www.readbyqxmd.com/read/28052556/platinum-plus-bortezomib-for-the-treatment-of-pediatric-renal-medullary-carcinoma-two-cases
#17
Marcus A Carden, Stephen Smith, Holly Meany, Hong Yin, Adina Alazraki, Louis B Rapkin
Renal medullary carcinoma (RMC) was first described over two decades ago as the seventh sickle nephropathy. Survival after diagnosis with metastatic disease still rarely extends beyond 1 year, with recent reports of median overall survival in patients treated with platinum therapy being just 10 months. We describe our experience using platinum-based chemotherapy plus the proteasome inhibitor bortezomib to treat metastatic RMC in two pediatric patients who had complete responses. One patient passed away 7 years after diagnosis, while another remains disease free nearly 2 years from diagnosis...
January 4, 2017: Pediatric Blood & Cancer
https://www.readbyqxmd.com/read/28052553/response-to-tobacco-use-among-siblings-of-childhood-cancer-survivors-a-report-from-the-childhood-cancer-survivor-study
#18
LETTER
David Buchbinder, E Anne Lown
No abstract text is available yet for this article.
January 4, 2017: Pediatric Blood & Cancer
https://www.readbyqxmd.com/read/28042910/whole-brain-radiotherapy-with-volumetric-modulated-arc-therapy-for-pediatric-intracranial-embryonic-carcinoma-prevents-permanent-alopecia
#19
LETTER
Atsushi Iwai, Katsutsugu Umeda, Megumi Uto, Hiroshi Nihira, Koji Kawaguchi, Masamitsu Mikami, Seishiro Nodomi, Satoshi Saida, Hidefumi Hiramatsu, Kengo Ogura, Masahiro Tanji, Yoshiki Arakawa, Tatsunori Sakamoto, Souichi Adachi, Takashi Mizowaki, Toshio Heike
No abstract text is available yet for this article.
January 2, 2017: Pediatric Blood & Cancer
https://www.readbyqxmd.com/read/28035790/a-pediatric-patient-with-glycogen-storage-disease-type-ia-and-castleman-disease
#20
LETTER
Branko Cuglievan, Brian A Menegaz, April DePombo, Ajaykumar C Morani, Roberto N Miranda, Michael Rytting
No abstract text is available yet for this article.
December 30, 2016: Pediatric Blood & Cancer
journal
journal
20217
1
2
Fetch more papers »
Fetching more papers... Fetching...
Read by QxMD. Sign in or create an account to discover new knowledge that matter to you.
Remove bar
Read by QxMD icon Read
×

Search Tips

Use Boolean operators: AND/OR

diabetic AND foot
diabetes OR diabetic

Exclude a word using the 'minus' sign

Virchow -triad

Use Parentheses

water AND (cup OR glass)

Add an asterisk (*) at end of a word to include word stems

Neuro* will search for Neurology, Neuroscientist, Neurological, and so on

Use quotes to search for an exact phrase

"primary prevention of cancer"
(heart or cardiac or cardio*) AND arrest -"American Heart Association"