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Pediatric Allergy and Immunology

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https://www.readbyqxmd.com/read/28786506/immunologic-study-of-two-fruit-induced-fpies-cases
#1
LETTER
Mª Victoria Moreno, Esther Caparrós, Javier Fernández, Purificación González-Delgado
FPIES is a severe non-IgE-mediated food hypersensitivity that typically occurs within the first months of life characterized by profuse vomiting and diarrhea, with progression to dehydration and shock in some patients (1). Normally, it is caused by cow's milk and/or soy but in the last years many other foods have been implicated. This article is protected by copyright. All rights reserved.
August 8, 2017: Pediatric Allergy and Immunology
https://www.readbyqxmd.com/read/28786498/food-induced-anaphylaxis-to-a-known-food-allergen-in-children-often-occurs-despite-adult-supervision
#2
LETTER
Sarah De Schryver, Ann Clarke, Sebastien La Vieille, Harley Eisman, Judy Morris, Rodrick Lim, Jocelyn Gravel, Moshe Ben-Shoshan
Food-related allergic reactions are the leading cause of anaphylaxis and emergency department visits and hospital admissions for food-induced anaphylaxis in children are increasing. Strict avoidance of food allergens is the main strategy in prevention of food-induced anaphylaxis and there are continuous efforts to educate patients and caregivers and to ensure proper food-labeling. This article is protected by copyright. All rights reserved.
August 8, 2017: Pediatric Allergy and Immunology
https://www.readbyqxmd.com/read/28783215/sensitization-to-dust-mite-defines-different-phenotypes-of-asthma-a-multicenter-study
#3
Silvia Ruggieri, Gaspare Drago, Valeria Longo, Paolo Colombo, Martin Balzan, David Bilocca, Christopher Zammit, Stephen Montefort, Gianluca Scaccianoce, Giuseppina Cuttitta, Giovanni Viegi, Fabio Cibella
BACKGROUND: Indoor allergens are risk factors for asthma: thus, the characterization of indoor air quality is important for studying environment-health relationships in children. In particular, Dermatophagoides pteronyssinus is the dominant allergen for asthma. We cross-sectionally investigated the relationships among respiratory symptoms and function, airway inflammation, allergen sensitization and indoor allergen concentration. METHODS: One hundred thirty two children aging 10-14 years and living in a Southern Mediterranean area were evaluated by parental questionnaires...
August 7, 2017: Pediatric Allergy and Immunology
https://www.readbyqxmd.com/read/28782296/combining-anti-ige-with-oral-immunotherapy
#4
REVIEW
Chunrong Lin, Ivan T Lee, Vanitha Sampath, Chitra Dinakar, Rosemarie H DeKruyff, Lynda C Schneider, Kari C Nadeau
Food allergy is a significant medical problem that affects up to 8% of children in developed countries. At present, there are no curative therapies available in routine practice and management of food allergy involves strict allergen avoidance, education, and prompt treatment upon accidental exposure. Oral immunotherapy (OIT) is an efficacious experimental approach to food allergy and has been shown to provide a substantial benefit in terms of allergen desensitization. However, OIT is associated with high rates of allergic reactions, and the period of protection offered by OIT appears to be limited and highly variable...
August 7, 2017: Pediatric Allergy and Immunology
https://www.readbyqxmd.com/read/28782291/fatal-case-of-ataxia-telangiectasia-complicated-by-severe-epistaxis-due-to-nasal-telangiectasia-in-a-12-year-old-boy
#5
LETTER
Renate Krüger, Sören Marian Zappe, Katharina Stölzel, Horst von Bernuth, Volker Wahn, Steffen Knopke
Ataxia telangiectasia (AT) is a rare autosomal inherited disorder with progressive ataxia, cutaneous and ocular telangiectasia, and an increased risk for malignancies due to chromosomal instability and varying degrees of immunodeficiency. Telangiectasia mostly occurs in eyes and sun exposed skin areas. However, mucosal bleeding due to telangiectasia within the vesical bladder has been reported. We, for the first time, report massive epistaxis in a 12 year old boy with AT due to multiple endonasal telangiectasias...
August 7, 2017: Pediatric Allergy and Immunology
https://www.readbyqxmd.com/read/28782222/ige-reactivity-to-shrimp-allergens-in-infants-and-their-cross-reactivity-to-house-dust-mite
#6
LETTER
Sandip D Kamath, Elecia B Johnston, Swati Iyer, Patrick M Schaeffer, Jennifer Koplin, Katrina Allen, Andreas L Lopata
The rise in shellfish allergy incidence, accompanying an increase in consumption and exposure to shellfish allergens, has become a serious problem worldwide. Precise diagnosis of shellfish allergy poses a challenge due to the diversity of consumed species, and immunological cross-reactivity to similar invertebrate pan-allergens. Moreover, variable concentrations of major and minor allergens in diagnostic preparations often result in false-negative results. This article is protected by copyright. All rights reserved...
August 7, 2017: Pediatric Allergy and Immunology
https://www.readbyqxmd.com/read/28782200/should-lip-dosing-be-reconsidered-when-performing-open-food-challenges
#7
LETTER
Carina Venter, Kate Maslin, Jane Grundy, Gillian Glasbey, Tara Dean
A lip dose or labial food challenge (LFC) is a simple, easy to perform method of diagnosis that could potentially be a convenient alternative to conducting an oral food challenge in children (1). Rance and Dutau (1) published a paper on LFC in 1997 demonstrating their clinical utility, according to the technique described by Moneret-Vautrin et al. (2). This involved a drop of the allergen being placed on the lower lip and left for 10 seconds to two minutes, with the mouth slightly opened. However, in the study by Rance et al...
August 7, 2017: Pediatric Allergy and Immunology
https://www.readbyqxmd.com/read/28779496/vaccination-and-allergy-eaaci-position-paper-practical-aspects
#8
REVIEW
Lennart Nilsson, Knut Brockow, Johan Alm, Victoria Cardona, Jean-Christoph Caubet, Eva Gomes, Maria C Jenmalm, Susanne Lau, Eva Netterlid, Jürgen Schwarze, Aziz Sheikh, Jann Storsaeter, Chrysanthi Skevaki, Ingrid Terreehorst, Giovanna Zanoni
Immunization is highly effective in preventing infectious diseases and therefore an indispensable public health measure. Allergic patients deserve access to the same publicly recommended immunizations as nonallergic patients unless risks associated with vaccination outweigh the gains. Whereas the number of reported possible allergic reactions to vaccines is high, confirmed vaccine-triggered allergic reactions are rare. Anaphylaxis following vaccination is rare, affecting less than 1/100,000, but can occur in any patient...
August 4, 2017: Pediatric Allergy and Immunology
https://www.readbyqxmd.com/read/28755494/breastfeeding-is-associated-with-a-decreased-risk-of-childhood-asthma-exacerbations-later-in-life
#9
Fariba Ahmadizar, Susanne J H Vijverberg, Hubertus G M Arets, Anthonius de Boer, Johan Garssen, Aletta D Kraneveld, Anke H Maitland-van der Zee
BACKGROUND: Breastfeeding has been suggested to influence the risk of asthma and asthma severity in children. However, the conclusions from epidemiological studies are inconsistent. METHODS: We used data from 960 children (aged 4-12 years) using regular asthma medication who participated in the PACMAN study. Breastfeeding exposure was based on questionnaire data and stratified into: 1) ever versus never, and 2) ≥6 versus <6 months duration of breastfeeding...
July 29, 2017: Pediatric Allergy and Immunology
https://www.readbyqxmd.com/read/28755473/personalized-treatment-of-severe-atopic-dermatitis-in-a-child-a-ten-year-follow-up
#10
LETTER
Simona Barni, Francesca Mori, Barbara Bortone, Elio Novembre
A 4-year-old-boy with a history of persistent rhinitis and milk and/or egg induced anaphylaxis was first referred to our Allergy Unit in 2008 because of severe atopic dermatitis (AD) since the age of one month. The physical examination was remarkable due to lichenified plaques, scaly and excoriated patchy papules (Figure 1). Moreover he complained of persistent generalized itchiness, with sleeping difficulties which greatly affected his quality of life. This article is protected by copyright. All rights reserved...
July 29, 2017: Pediatric Allergy and Immunology
https://www.readbyqxmd.com/read/28692169/the-relationship-between-anxiety-and-quality-of-life-in-children-with-hereditary-angioedema
#11
Aharon Kessel, Henriette Farkas, Shmuel Kivity, Nóra Veszeli, Kinga Viktória Kőhalmi, Batya Engel-Yeger
BACKGROUND: The severe life-threatening characteristics of hereditary angioedema (HAE) with C1-inhibitor deficiency (C1-INH-HAE) can affect anxiety levels among pediatric patients. This emotional burden together with the physical restrictions of C1-INH-HAE may decrease children's health-related quality of life (HRQoL). OBJECTIVE: (1) To compare anxiety state and trait between children with C1-INH-HAE and healthy controls (2) To examine the relationship between the level of anxiety of children with C1-INH-HAE, their disease activity/affected sites and their HRQoL (3) To predict the HRQoL of children with C1-INH-HAE based on their anxiety level and disease activity/affected sites...
July 10, 2017: Pediatric Allergy and Immunology
https://www.readbyqxmd.com/read/28692145/efficacy-and-safety-of-tiotropium-in-school-age-children-with-moderate-to-severe-symptomatic-asthma-a-systematic-review
#12
Gustavo J Rodrigo, Hugo Neffen
BACKGROUND: Recently published data support the benefits and safety of the once-daily (OD) long-acting anticholinergic tiotropium bromide bronchodilator for the treatment of uncontrolled moderate to severe asthma in adults and adolescents. However, its role for the treatment of school-age asthmatics has not yet been clearly defined. The aim of this systematic review was to assess the efficacy and safety of tiotropium Respimat(®) in children aged 6-11 years with moderate to severe symptomatic asthma...
July 10, 2017: Pediatric Allergy and Immunology
https://www.readbyqxmd.com/read/28686792/igg-subclass-deficiencies-in-children-facts-and-fiction
#13
REVIEW
Volker Wahn, Horst von Bernuth
The chance to analyse the four IgG subclasses arose with the publication of Terry and Fahey(1) . Since then, a lot of new information on the role of subclasses and their deficiency states in humans has been obtained. This review tries to analyse critically our current knowledge of subclass deficiencies in children.
July 7, 2017: Pediatric Allergy and Immunology
https://www.readbyqxmd.com/read/28686791/adherence-and-stress-in-a-population-of-inner-city-children-with-asthma
#14
LETTER
Meredith A Dilley, Carter R Petty, William J Sheehan, Jonathan M Gaffin, Marissa Hauptman, Wanda Phipatanakul
No abstract text is available yet for this article.
July 7, 2017: Pediatric Allergy and Immunology
https://www.readbyqxmd.com/read/28686349/the-role-of-vitamin-d-on-circulating-memory-t-cells-in-children-the-generation-r-study
#15
Kirsten I M Looman, Michelle A E Jansen, Trudy Voortman, Diana van den Heuvel, Vincent W V Jaddoe, Oscar H Franco, Menno C van Zelm, Henriëtte A Moll
BACKGROUND: Previous studies have demonstrated that vitamin D affects T-cell function and maturation via the vitamin D receptor. However, no studies in children have been performed on this topic. Because most of the T-cell memory is formed in the first 5 years of life, we aimed to determine the association between serum 25-hydroxyvitamin D (25(OH)D) levels and numbers of circulatory naive, central memory (Tcm), and effector memory (Tem) T lymphocytes in a large population of healthy children...
July 7, 2017: Pediatric Allergy and Immunology
https://www.readbyqxmd.com/read/28686314/several-patient-reported-outcome-measures-exist-for-children-with-atopic-eczema-dermatitis-but-their-validity-is-largely-unknown
#16
LETTER
Christian J Apfelbacher, Daniel Heinl, Helen E Smith
No abstract text is available yet for this article.
July 7, 2017: Pediatric Allergy and Immunology
https://www.readbyqxmd.com/read/28686311/anaphylaxis-to-horses-and-epinephrine-use-increasing-awareness-among-pediatric-patients-and-families
#17
LETTER
Wilfredo Cosme-Blanco, Eduardo López-Medina, Sylvia Morales-Bronner, William Blouin, Vivian Hernandez-Trujillo
No abstract text is available yet for this article.
July 7, 2017: Pediatric Allergy and Immunology
https://www.readbyqxmd.com/read/28661552/asthma-treatment-patterns-in-dutch-children-using-medication-dispensing-data
#18
LETTER
Ali Arabkhazaeli, Susanne J H Vijverberg, C Kors van der Ent, Jan A M Raaijmakers, Anke H Maitland-van der Zee
No abstract text is available yet for this article.
June 29, 2017: Pediatric Allergy and Immunology
https://www.readbyqxmd.com/read/28660739/pooled-efficacy-and-safety-data-for-house-dust-mite-sublingual-immunotherapy-tablets-in-adolescents
#19
Tomokazu Matsuoka, David I Bernstein, Keisuke Masuyama, Hendrik Nolte, Kazuhiro Okamiya, Dorthe Seitzberg, Harold S Nelson
BACKGROUND: House dust mite (HDM) respiratory allergy is a common and burdensome disease in children and adolescents. There are few HDM allergy immunotherapy trials in children with perennial allergic rhinitis. This post hoc analysis used pooled data to evaluate efficacy and safety of the SQ HDM sublingual immunotherapy (SLIT) tablet in adolescents (12-17 years). METHODS: In 2 double-blind, placebo-controlled trials conducted in North America and Japan, respectively, subjects aged 12+ years with HDM allergic rhinitis were randomized to up to one year of treatment...
June 29, 2017: Pediatric Allergy and Immunology
https://www.readbyqxmd.com/read/28660720/prednisolone-for-the-first-rhinovirus-induced-wheezing-and-4-year-asthma-risk-a-randomized-trial
#20
Annamari Koistinen, Minna Lukkarinen, Riitta Turunen, Tytti Vuorinen, Tero Vahlberg, Carlos A Camargo, James Gern, Olli Ruuskanen, Tuomas Jartti
BACKGROUND: Previous findings show that corticosteroid treatment during the first acute wheezing episode may reduce recurrent wheezing in children with high rhinovirus genome load at 12-month follow-up. Longer-term effects have not been investigated prospectively. METHODS: After PCR confirmation of rhinovirus from nasopharyngeal aspirate, 79 children with the first acute wheezing episode were randomized to receive orally prednisolone or placebo for 3 days. The initiation of asthma control medication before the age of 5 years was confirmed from medical record and/or from parental interview...
June 29, 2017: Pediatric Allergy and Immunology
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