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Pathogens and Global Health

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https://www.readbyqxmd.com/read/27908227/improved-infant-hemoglobin-hb-and-blood-glucose-concentrations-the-beneficial-effect-of-maternal-vitamin-a-supplementation-of-malaria-infected-mothers-in-ebonyi-state-nigeria
#1
Michael O Elom, Joseph E Eyo, Fabian C Okafor, Amos Nworie, Victor U Usanga, Gerald N Attamah, Chibueze C Igwe
One hundred and fifty-two malaria-infected pregnant women whose pregnancies had advanced to the 6th month were randomised into two study groups - supplemented and placebo groups, after obtaining their approved consents. Ten thousand international units of vitamin A soft gels were administered to the supplemented group three times per week. Vitamin A soft gels devoid of their active ingredients were administered thrice weekly to the placebo group. Two hundred thousand international units of vitamin A was administered to the supplemented groups within 8 weeks postpartum...
December 1, 2016: Pathogens and Global Health
https://www.readbyqxmd.com/read/27905267/zika-concerns-and-reality
#2
Antonio Cassone
No abstract text is available yet for this article.
December 1, 2016: Pathogens and Global Health
https://www.readbyqxmd.com/read/27903130/risk-factors-and-mortality-in-the-carbapenem-resistant-klebsiella-pneumoniae-infection-case-control-study
#3
Fethiye Akgul, Ilkay Bozkurt, Mustafa Sunbul, Saban Esen, Hakan Leblebicioglu
Carbapenem-resistant Klebsiella pneumoniae (CRKP) has been known as a nosocomial pathogen, both for the last 10 years in Turkey and for 20 years worldwide. Due to limited treatment options and high mortality rates, despite improvements in the field of medicine at the present time, CRKP is still a big threat for public health. This study was carried out between the dates of January 2010 and September 2014. Patients ≥18 who were hospitalized for at least 72 h and who also had CRKP growth were included in the study as a case group...
December 1, 2016: Pathogens and Global Health
https://www.readbyqxmd.com/read/27892799/antiviral-treatment-of-hbv-positive-pregnant-women-an-additional-tool-to-reduce-perinatal-transmission
#4
Roberto Bruni, Gloria Taliani, Anna Rita Ciccaglione
No abstract text is available yet for this article.
November 28, 2016: Pathogens and Global Health
https://www.readbyqxmd.com/read/27871210/para-kala-azar-dermal-leishmaniasis-cases-in-indian-subcontinent-a-case-series
#5
Rakesh Kumar, Vidya Nand Rabi Das, Roshan Kamal Topno, Biplab Pal, Adnan Imam, Kanhaiya Agrawal, Anima Singh, Krishna Murti, Chandra Shekhar Lal, Neena Verma, Pradeep Das, Krishna Pandey
No abstract text is available yet for this article.
November 22, 2016: Pathogens and Global Health
https://www.readbyqxmd.com/read/27854189/molecular-detection-of-leishmania-parasites-and-host-blood-meal-identification-in-wild-sand-flies-from-a-new-endemic-rural-region-south-of-iran
#6
Kourosh Azizi, Mohammad Bagher Askari, Mohsen Kalantari, Mohammad Djaefar Moemenbellah-Fard
Zoonotic Cutaneous Leishmaniosis (ZCL) remains the most crucial vector-borne public health disease particularly in endemic rural parts of Iran. The main aim of this study is to identify wild sand flies (Diptera: Psychodidae), determine their infection rate, and differentiate their host blood meal sources using the polymerase chain reaction-restriction fragment length polymorphism (PCR-RFLP) technique. Sand fly populations were caught with sticky paper traps from 10 different villages in the county of Darab, Fars province, southern Iran...
November 17, 2016: Pathogens and Global Health
https://www.readbyqxmd.com/read/27852150/frequency-diagnostic-performance-of-coproantigen-detection-and-genotyping-of-the-giardia-among-patients-referred-to-a-multi-level-teaching-hospital-in-northern-india
#7
Ujjala Ghoshal, Ratnakar Shukla, Priyannk Pant, Uday C Ghoshal
Giardiasis, a common gastrointestinal parasitic infection in tropics, is diagnosed on stool microscopy (gold standard); however, its sensitivity is low due to intermittent fecal shedding. Coproantigen detection (ELISA) is useful but requires further evaluation. We aimed to study: (a) detection of Giardia by stool microscopy and/or coproantigen, (b) diagnostic performance of fecal antigen detection and microscopy, and c) genotypic characterization of G. lamblia using PCR specific for triose phosphate isomerase (tpi) gene...
November 17, 2016: Pathogens and Global Health
https://www.readbyqxmd.com/read/27830997/impact-of-hiv-infection-in-patients-infected-with-chronic-hcv-genotypes-1a-and-3a-virological-and-clinical-changes
#8
Daryoush Behzadpour, Abbas Ahmadi Vasmehjani, Seyed Dawood Mousavi Nasab, Nayeb Ali Ahmadi, Rasoul Baharlou
BACKGROUND: Human immunodeficiency virus (HIV)/hepatitis C virus (HCV) coinfection has become a serious public health problem. The influence of HIV/HCV coinfection on plasma HCV RNA loads and clinical criteria which are usually regarded as a predictor of the progress of liver disease have not been reliably evaluated. OBJECTIVES: This study investigated the impact of HIV infection on HCV RNA load and clinical indexes in Yazd and Tehran. MATERIALS AND METHODS: HCV/HIV-coinfected patients and HCV-monoinfected controls were examined and compared for plasma HCV RNA and related risk factors such as HCV genotypes, liver enzymes, and transmission routes...
November 10, 2016: Pathogens and Global Health
https://www.readbyqxmd.com/read/27788631/detection-of-occult-hepatitis-b-and-window-period-infection-among-blood-donors-by-individual-donation-nucleic-acid-testing-in-a-tertiary-care-center-in-south-india
#9
Cinzia S Keechilot, Veena Shenoy, Anil Kumar, Lalitha Biswas, Sukhithasri Vijayrajratnam, Kavitha Dinesh, Prem Nair
With the introduction of highly sensitive hepatitis B surface antigen immunoassay, transfusion associated HBV infection have reduced drastically but they still tend to occur due to blood donors with occult hepatitis B infection (OBI) and window period (WP) infection. Sera from, 24338 healthy voluntary blood donors were screened for HBsAg, HIV and HCV antibody using Vitros Enhanced Chemiluminescent Immunoassay. The median age of the donor population was 30 (range 18-54) with male preponderance (98%). All serologically negative samples were screened by nucleic acid testing (NAT) for viral DNA and RNA...
October 27, 2016: Pathogens and Global Health
https://www.readbyqxmd.com/read/27697019/identification-production-and-assessment-of-two-toxoplasma-gondii-recombinant-proteins-for-use-in-a-toxoplasma-igg-avidity-assay
#10
Ai Ying Teh, Atefeh Amerizadeh, Sabariah Osman, Muhammad Hafiznur Yunus, Rahmah Noordin
The IgG avidity assay is an important tool in the management of suspected toxoplasmosis in pregnant women. This study aimed to produce new Toxoplasma gondii recombinant proteins and to assess their usefulness in an IgG avidity assay. Toxoplasma positive and negative serum samples were used, the former were categorized into low (LGA) and high (HGA) IgG avidity samples. Immunoblots were performed on 30 T. gondii cDNA clones to determine the reactivity and IgG avidity to the expressed proteins. Two of the clones were found to have diagnostic potential and were analyzed further; AG12b encoded T...
October 4, 2016: Pathogens and Global Health
https://www.readbyqxmd.com/read/27690200/zika-virus-infection-and-pregnancy-what-we-do-and-do-not-know
#11
Carlo Ticconi, Adalgisa Pietropolli, Giovanni Rezza
Recent data strongly suggest an association between the current outbreak of ZIKA virus (ZIKV) in many countries of Central and South America and a sharp increase in the detection of microcephaly and fetal malformations. The link with brain defect, which has been detected mainly in some areas of Brazil, is supported by the following evidence: (1) ZIKV transmission from infected pregnant women to their fetuses; (2) the potential of ZIKV to determine a specific congenital fetal syndrome characterized by abnormalities involving primarily the developing brain and eye...
September 30, 2016: Pathogens and Global Health
https://www.readbyqxmd.com/read/27670692/phylogenesys-and-homology-modeling-in-zika-virus-epidemic-food-for-thought
#12
Silvia Angeletti, Alessandra Lo Presti, Marta Giovanetti, Alba Grifoni, Massimo Amicosante, Marco Ciotti, Luiz-Carlos J Alcantara, Eleonora Cella, Massimo Ciccozzi
Zika virus (ZIKV) is an emerging Flavivirus that have recently caused an outbreak in Brazil and rapid spread in several countries. In this study, the consequences of ZIKV evolution on protein recognition by the host immune system have been analyzed. Evolutionary analysis was combined with homology modeling and T-B cells epitope predictions. Two separate clades, the African one with the Uganda sequence, as the most probable ancestor, and the second one containing all the most recent sequences from the equatorial belt were identified...
September 27, 2016: Pathogens and Global Health
https://www.readbyqxmd.com/read/27680296/early-marriage-and-pregnancy-among-syrian-adolescent-girls-in-jordan-do-they-have-a-choice
#13
Shible Sahbani, Maysa Al-Khateeb, Ruba Hikmat
No abstract text is available yet for this article.
September 2016: Pathogens and Global Health
https://www.readbyqxmd.com/read/27666187/the-detection-of-trypanosoma-cruzi-by-nested-pcr-in-elderly-patients-relationship-to-the-clinical-and-epidemiological-profile
#14
Mariane Barroso Pereira, Angélica Martins Batista, Camila Aguiar, Glaucia Elisete Barbosa Marcon, Luiz Cláudio Martins, Maria Elena Guariento, Sandra Cecília Botelho Costa, Eros Antonio de Almeida
Chagas disease, which is caused by Trypanosoma cruzi, is transmitted primarily by triatomine bugs, although the incidence of new cases has decreased as a result of vector control. In Brazil, most of those affected have the chronic form of the disease and are generally elderly individuals who require appropriate clinical follow-up. In this work, we undertook a descriptive study in which 85 patients were interviewed and blood samples were collected for molecular analyses based on the amplification of parasite satellite DNA...
September 2016: Pathogens and Global Health
https://www.readbyqxmd.com/read/27660895/pro-and-anti-inflammatory-cytokines-in-cutaneous-leishmaniasis-a-review
#15
Nahid Maspi, Amir Abdoli, Fathemeh Ghaffarifar
Cutaneous leishmaniasis (CL) is caused by different species of the genus Leishmania. Pro- and anti-inflammatory cytokines play different roles in resistance/susceptibility and the immunopathogenesis of Leishmania infection. The balance and dynamic changes in cytokines may control or predict clinical outcome. T helper 1 (Th1) inflammatory cytokines (especially interferon-γ, tumor necrosis factor-α and interleukin-12) are the crucial factors in the initiation of protective immunity against L. major infection, whereas T helper 2 cytokines including IL-5, IL-4, and IL-13 facilitate the persistence of parasites by downregulating the Th1 immune response...
September 2016: Pathogens and Global Health
https://www.readbyqxmd.com/read/27650884/intestinal-carriage-of-multidrug-resistant-gram-negative-bacteria-in-preterm-infants-during-hospitalization-in-neonatal-intensive-care-unit-nicu
#16
Polly Soo Xi Yap, Azanna Ahmad Kamar, Chun Wie Chong, Ivan Kok Seng Yap, Kwai Lin Thong, Yao Mun Choo, Mohd Yasim Md Yusof, Cindy Shuan Ju Teh
The prevalence and antibiotic susceptibility of intestinal carriage of Gram-negative bacteria among preterm infants admitted to the neonatal intensive care unit (NICU) in a tertiary teaching hospital in Malaysia were determined. A total of 34 stool specimens were obtained from preterm infants upon admission and once weekly up to two weeks during hospitalization. The presumptive colonies of Escherichia coli and Klebsiella pneumoniae were selected for identification, antibiotic susceptibility testing, and subtyping by using pulsed-field gel electrophoresis (PFGE)...
September 2016: Pathogens and Global Health
https://www.readbyqxmd.com/read/27646838/laboratory-diagnosis-and-genetic-analysis-of-a-family-clustering-outbreak-of-aseptic-meningitis-due-to-echovirus-30
#17
Shufa Zheng, Hongyan Ye, Juying Yan, Guoliang Xie, Dawei Cui, Fei Yu, Yiyin Wang, Xianzhi Yang, Fangman Zhou, Yanjun Zhang, Xueli Tian, Yu Chen
Echovirus 30 (E30) is a major pathogen associated with aseptic meningitis. In the summer of 2014, a family clustering aseptic meningitis outbreak occurred in urban-rural fringe of Ningbo city in Zhejiang Province in China. To identify the etiologic agent, specimens were tested by cell culture and reverse transcriptase-polymerase chain reaction. Pathogenic examination confirmed that the outbreak is caused by E30. The first case is a 6-year-old child, who studied in kindergarten in local, suffered from headache and fever...
September 2016: Pathogens and Global Health
https://www.readbyqxmd.com/read/27560094/lack-of-household-clustering-of-malaria-in-a-complex-humanitarian-emergency-implications-for-active-case-detection
#18
Hasan Hamze, Rhianna Charchuk, Makelele Katsuva Jean Paul, Kasereka Masumbuko Claude, Mashukano Léon, Michael T Hawkes
BACKGROUND: Malaria contributes to elevated morbidity and mortality in populations displaced by conflict in tropical zones. In an attempt to reduce malaria transmission in an internally displaced persons (IDP) camp in eastern Democratic Republic of Congo (DRC), we tested a strategy of active case detection of household contacts of malaria cases. METHODS: Prospective community-based survey. RESULTS: From a convenience sample of 100 febrile patients under 5 years of age from the IDP camp presenting to a nearby clinic for management of a fever episode, 19 cases of uncomplicated malaria and 81 controls with non-malarial febrile illness (NFMI) were diagnosed...
September 2016: Pathogens and Global Health
https://www.readbyqxmd.com/read/27348132/m%C3%A3-decins-sans-fronti%C3%A3-res-and-the-refugee-crisis-in-greece-an-interview-with-dr-apostolos-veizis
#19
Christos Louis
No abstract text is available yet for this article.
September 2016: Pathogens and Global Health
https://www.readbyqxmd.com/read/27677379/aetiology-of-pcr-negative-suspected-crimean-congo-hemorrhagic-fever-cases-in-an-endemic-area
#20
Esra Tanyel, Mustafa Sunbul, Tom E Fletcher, Hakan Leblebicioglu
Crimean-Congo hemorrhagic fever (CCHF) is a potentially fatal tick-borne viral infection that is widely distributed worldwide. The diagnosis is frequently missed due to the non-specific initial symptoms and the differential diagnosis included many infectious and non-infectious causes. This retrospective study describes the clinical features and final diagnoses of 116 suspect CCHF cases that were admitted to a tertiary CCHF center in Turkey, and were CCHF IgM and PCR negative.
June 2016: Pathogens and Global Health
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