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Pathogens and Global Health

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https://www.readbyqxmd.com/read/28645237/homologous-microscopic-agglutinating-antibodies-after-natural-infection-with-leptospires-results-from-a-long-term-follow-up-of-a-cohort-living-in-an-endemic-area
#1
R Vimal Raj, K Vinod Kumar, A P Sugunan, K Natarajaseenivasan, P Vijayachari
No abstract text is available yet for this article.
June 23, 2017: Pathogens and Global Health
https://www.readbyqxmd.com/read/28605993/in-vitro-sensitivity-to-antimalarial-drugs-and-polymorphisms-in-pfg377-gene-in-plasmodium-falciparum-field-isolates-from-mewat-india
#2
Vineeta Singh, Amit Kumar, Purva Gupta
The malaria infection is the interplay of several complex factors, among which drug resistance and gametocyte biology are the crucial ones. Measurements of the drug sensitivity assays and prevalence of gametocyte genes play a major role in malaria eradication programmes. The purpose of this study was to assess the current drug sensitivity profile in the field isolates and type the Pfg377 gene. In vitro drug sensitivity assay was used to assess the susceptibility of Plasmodium falciparum field isolates collected from Mewat (Haryana), located in Northern region of India to four anti-malarial drugs...
June 12, 2017: Pathogens and Global Health
https://www.readbyqxmd.com/read/28549390/clinical-and-molecular-monitoring-of-plasmodium-falciparum-resistance-to-antimalarial-drug-artesunate-sulphadoxine-pyrimethamine-in-two-highly-malarious-district-of-madhya-pradesh-central-india-from-2012-2014
#3
Sweta Mishra, Praveen K Bharti, Man M Shukla, Nazia A Ali, Sher S Kashyotia, Avdhesh Kumar, Akshay C Dhariwal, Neeru Singh
The spread of P. falciparum resistant strain has led to a significant resurgence of malaria morbidity and mortality. The current cornerstone in malaria treatment in India is Artemisinin based Combination (Artesunate + Sulphadoxine-Pyrimethamine) Therapy (ACT) for treatment of uncomplicated P. falciparum malaria since 2010. In the present study we assessed the therapeutic efficacy of ACT and molecular monitoring of antimalarial resistance. Therapeutic efficacy was determined by in vivo method using 28 days follow-up...
May 26, 2017: Pathogens and Global Health
https://www.readbyqxmd.com/read/28502227/malaria-and-severe-anemia-over-eight-years-at-gambo-rural-hospital-southern-ethiopia
#4
Pablo Barreiro, Gebre Tiziano, Haji Fano, Tafesse Yohannes, Ashenafi Gosa, Francisco Reyes, Abraham Tesfamariam, Miguel Górgolas, José M Ramos
Evolution of incident malaria and frequency of anemia were analyzed over eight years in a rural hospital in southern Ethiopia. Capillary blood samples were tested for hemoglobin concentration, and in some instances for malaria parasites, at Gambo Rural General Hospital between January 2007 and September 2014, and the results recorded. Main demographic data were also recorded in subjects with Plasmodium sp. infections. Of a total of 54,493 blood samples taken from 45,096 different patients, 21,723 (39.9%) samples from 19,173 (42...
May 13, 2017: Pathogens and Global Health
https://www.readbyqxmd.com/read/28486849/vaccination-refusal-autonomy-and-permitted-coercion
#5
Andrzej Grzybowski, Rafał K Patryn, Jarosław Sak, Anna Zagaja
The article presents vaccination obligation in relation to the existing or newly enacted legislation. Mass vaccinations and a wave of criticism they cause, forces us to reflect on the limits of medical intervention in the human body and the boundaries granted to individual's freedom and autonomy. This problem is universal and exists mainly in countries without mandatory vaccinations. Analyzing recent years, it must be underlined that a process in some legislatures has been introduced to enforce various forms of vaccination coercion...
May 9, 2017: Pathogens and Global Health
https://www.readbyqxmd.com/read/28403683/whole-genome-sequencing-of-klebsiella-pneumoniae-mdr-strain-isolated-in-a-syrian-refugee
#6
Silvia Angeletti, Eleonora Cella, Alessia Lai, Alessandra Lo Presti, Francesca Antonelli, Alessia Conti, Maurizio Lopalco, Silvia Spoto, Gianguglielmo Zehender, Massimo Ciccozzi
No abstract text is available yet for this article.
April 12, 2017: Pathogens and Global Health
https://www.readbyqxmd.com/read/28395597/genome-sequencing-and-comparative-analysis-of-an-ndm-1-producing-klebsiella-pneumoniae-st15-isolated-from-a-refugee-patient
#7
Tamara Salloum, Harout Arabaghian, Sahar Alousi, Edmond Abboud, Sima Tokajian
The escalating problem of antibiotic resistance, specifically cabarpenemase and extended-spectrum β-lacatamase (ESBL) producing K. pneumoniae strains, is directly correlated with increased patient morbidity and mortality and prolonged hospitalization and costs. In this study, a comprehensive genomic analysis encompassing the resistomics, virulence repertoire and mobile genetic elements of an NDM-1 positive ESBL-producing K. pneumoniae EA-MEH ST15 isolated from a urine sample collected from a Syrian refugee was conducted...
April 11, 2017: Pathogens and Global Health
https://www.readbyqxmd.com/read/28385129/in-vitro-antileishmanial-activity-of-fisetin-flavonoid-via-inhibition-of-glutathione-biosynthesis-and-arginase-activity-in-leishmania-infantum
#8
Keivan Adinehbeigi, Mohammad Hossein Razi Jalali, Ali Shahriari, Somayeh Bahrami
With the increasing emergence of drug resistant Leishmania sp. in recent years, combination therapy has been considered as a useful way to treat and control of Leishmaniasis. The present study was designed to evaluate the antileishmanial effects of the fisetin alone and combination of fisetin plus Meglumine antimoniate (Fi-MA) against Leishmania infantum. The IC50 values for fisetin were obtained 0.283 and 0.102 μM against promastigotes and amastigote forms, respectively. Meglumine antimoniate (MA, Glucantime) as control drug also revealed IC50 values of 0...
April 7, 2017: Pathogens and Global Health
https://www.readbyqxmd.com/read/28605992/the-third-international-workshop-on-aedes-albopictus-building-scientific-alliances-in-the-fight-against-the-globally-invasive-asian-tiger-mosquito
#9
Robert M Waterhouse, Xiaoguang Chen, Mariangela Bonizzoni, Giuliano Gasperi
No abstract text is available yet for this article.
June 2017: Pathogens and Global Health
https://www.readbyqxmd.com/read/28367735/severe-vivax-malaria-a-prospective-exploration-at-a-tertiary-healthcare-centre-in-southwestern-india
#10
Rishikesh Kumar, Kavitha Saravu
Plasmodium vivax is recognized to cause severe malaria and mortality. We aimed to determine the proportion of disease severity, the spectrum of complications, underlying non-infectious comorbidities and predictors of severity in monoinfection P. vivax malaria among adults at a tertiary healthcare centre in Southwestern India. A prospective cohort study was conducted among microscopically confirmed monoinfection P. vivax acute malaria patients aged, ≥18 years. Cases with pregnancy and concomitant febrile illnesses including mixed malaria were excluded...
May 2017: Pathogens and Global Health
https://www.readbyqxmd.com/read/28362226/camel-as-a-transboundary-vector-for-emerging-exotic-salmonella-serovars
#11
Nahed H Ghoneim, Khaled A Abdel-Moein, Hala Zaher
The current study was conducted to shed light on the role of imported camels as a transboundary vector for emerging exotic Salmonella serovars. Fecal samples were collected from 206 camels directly after slaughtering including 25 local camels and 181 imported ones as well as stool specimens were obtained from 50 slaughterhouse workers at the same abattoir. The obtained samples were cultured while Salmonella serovars were identified through Gram's stain films, biochemical tests and serotyping with antisera kit...
May 2017: Pathogens and Global Health
https://www.readbyqxmd.com/read/28353411/polymyxin-b-and-vancomycin-associated-acute-kidney-injury-in-critically-ill-patients
#12
Douglas de Sousa Soares, André da Fonte Reis, Geraldo Bezerra da Silva Junior, Tacyano Tavares Leite, Sérgio Luiz Arruda Parente Filho, Carina Vieira de Oliveira Rocha, Elizabeth De Francesco Daher
BACKGROUND: This study aims to investigate renal toxicities of Polymyxin B and Vancomycin among critically ill patients and risk factors for acute kidney injury (AKI). METHODS: This is a cross-sectional study conducted with patients admitted to an intensive care unit (ICU) of a tertiary hospital in Brazil. Patients were divided into two groups: those who used association of Polymyxin B + Vancomycin (Group I) and those who used only Polymyxin B (Group II). Risk factors for AKI were also analyzed...
May 2017: Pathogens and Global Health
https://www.readbyqxmd.com/read/28353409/what-do-we-know-about-the-role-of-regulatory-b-cells-breg-during-the-course-of-infection-of-two-major-parasitic-diseases-malaria-and-leishmaniasis
#13
Roberta Reis Soares, Luciana Maria Ribeiro Antinarelli, Clarice Abramo, Gilson Costa Macedo, Elaine Soares Coimbra, Kézia Katiani Gorza Scopel
Parasitic diseases, such as malaria and leishmaniasis, are relevant public health problems worldwide. For both diseases, the alarming number of clinical cases and deaths reported annually has justified the incentives directed to better understanding of host's factors associated with susceptibility to infection or protection. In this context, over recent years, some studies have given special attention to B lymphocytes with a regulator phenotype, known as Breg cells. Essentially important in the maintenance of immunological tolerance, especially in autoimmune disease models such as rheumatoid arthritis and experimentally induced autoimmune encephalomyelitis, the function of these lymphocytes has so far been poorly explored during the course of diseases caused by parasites...
May 2017: Pathogens and Global Health
https://www.readbyqxmd.com/read/28335696/development-and-initial-evaluation-of-a-lateral-flow-dipstick-test-for-antigen-detection-of-entamoeba-histolytica-in-stool-sample
#14
Syazwan Saidin, Muhammad Hafiznur Yunus, Nurulhasanah Othman, Yvonne Ai-Lian Lim, Zeehaida Mohamed, Nik Zairi Zakaria, Rahmah Noordin
Entamoeba histolytica infection remains a public health concern in developing countries. Early diagnosis of amoebiasis can avoid disease complications, thus this study was aimed at developing a test that can rapidly detect the parasite antigens in stool samples. Rabbits were individually immunized with recombinant pyruvate phosphate dikinase (rPPDK) and E. histolytica excretory-secretory antigens to produce polyclonal antibodies. A rapid dipstick test was produced using anti-rPPDK PAb lined on the dipstick as capture reagent and anti-EhESA PAb conjugated to colloidal gold as the detector reagent...
May 2017: Pathogens and Global Health
https://www.readbyqxmd.com/read/28279129/association-of-enteric-parasitic-infections-with-intestinal-inflammation-and-permeability-in-asymptomatic-infants-of-s%C3%A3-o-tom%C3%A3-island
#15
Marisol Garzón, Luis Pereira-da-Silva, Jorge Seixas, Ana Luísa Papoila, Marta Alves, Filipa Ferreira, Ana Reis
The cumulative effect of repeated asymptomatic enteric infections on intestinal barrier is not fully understood in infants. We aimed to evaluate the association between previous enteric parasitic infections and intestinal inflammation and permeability at 24-months of age, in asymptomatic infants of São Tomé Island. A subset of infants from a birth cohort, with intestinal parasite evaluations in at least four points of assessment, was eligible. Intestinal inflammatory response and permeability were assessed using fecal S100A12 and alpha-1-antitrypsin (A1AT), respectively...
May 2017: Pathogens and Global Health
https://www.readbyqxmd.com/read/28274195/quality-control-and-data-validation-procedure-in-large-scale-quantitative-monitoring-of-mosquito-density-the-case-of-aedes-albopictus-in-emilia-romagna-region-italy
#16
Marco Carrieri, Alessandro Albieri, Sandra Urbanelli, Paola Angelini, Claudio Venturelli, Carmela Matrangolo, Romeo Bellini
The risk of local transmission of chikungunya, dengue, and Zika viruses from viremic travelers arriving from affected areas is a real possibility in southern Europe, due to the large presence of the vector Aedes albopictus. The first chikungunya outbreak in Europe occurred in the Emilia-Romagna region, Italy, in 2007, prompting the regional public health department to implement an Ae. albopictus monitoring and control plan. This paper presents the procedure developed for the quality control of the data collected by the regional ovitrap monitoring network...
March 2017: Pathogens and Global Health
https://www.readbyqxmd.com/read/28245722/the-epidemiological-investigation-and-control-of-an-anthrax-outbreak-in-a-village-in-central-anatolia-turkey
#17
Hayati Demiraslan, Arda Borlu, Serkan Sahin, Fatih Buyuk, Yunus Karadag, Mehmet Doganay, Mitat Sahin
No abstract text is available yet for this article.
March 1, 2017: Pathogens and Global Health
https://www.readbyqxmd.com/read/28221822/clinical-characteristics-and-spatial-distribution-of-visceral-leishmaniasis-in-children-in-s%C3%A3-o-paulo-state-an-emerging-focus-of-visceral-leishmaniasis-in-brazil
#18
Patricia Rodrigues Naufal Spir, Luiz Euribel Prestes-Carneiro, Elivelton Silva Fonseca, Aline Dayse, Rogério Giuffrida, Lourdes Aparecida Zampieri D'Andrea
BACKGROUND: Visceral leishmaniasis (VL) is an emerging zoonosis, and Brazil harbors about 90% of those infected in Latin America. Since 1998, the disease has been spreading quickly in São Paulo state, and the western region is considered an emerging focus of VL in Brazil. Our aim was to evaluate the clinical characteristics and spatial distribution of VL in children referred to a public tertiary hospital located in the western region of São Paulo state, Brazil. METHODS: Medical records of children up to 18 years of age who were diagnosed with VL between January 2006 and December 2010 were reviewed...
March 2017: Pathogens and Global Health
https://www.readbyqxmd.com/read/28220714/is-maternal-education-a-social-vaccine-for-childhood-malaria-infection-a-cross-sectional-study-from-war-torn-democratic-republic-of-congo
#19
Cary Ma, Kasereka Masumbuko Claude, Zacharie Tsongo Kibendelwa, Hannah Brooks, Xiaonan Zheng, Michael Hawkes
In zones of violent conflict in the tropics, social disruption leads to elevated child mortality, of which malaria is the leading cause. Understanding the social determinants of malaria transmission may be helpful to optimize malaria control efforts. We conducted a cross-sectional study of healthy children aged 2 months to 5 years attending well-child and/or immunization visits in the Democratic Republic of Congo (DRC). Six hundred and forty-seven children were tested for malaria antigenemia by rapid diagnostic test and the accompanying parent or legal guardian simultaneously completed a survey questionnaire related to demographics, socioeconomic status, maternal education, as well as bednet use and recent febrile illness...
March 2017: Pathogens and Global Health
https://www.readbyqxmd.com/read/28219255/the-surge-of-universal-influenza-vaccines
#20
Antonio Cassone
No abstract text is available yet for this article.
March 2017: Pathogens and Global Health
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