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Paediatric and Perinatal Epidemiology

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https://www.readbyqxmd.com/read/29053188/trends-in-risk-of-pregnancy-loss-among-us-women-1990-2011
#1
Lauren M Rossen, Katherine A Ahrens, Amy M Branum
BACKGROUND: Pregnancy loss can have physical and psychological consequences for women and their families. Though a previous study described an increase in the risk of self-reported pregnancy loss from 1970 to 2000, more recent examinations from population-based data of US women are lacking. METHODS: We used data from the 1995, 2002, 2006-2010, 2011-2015 National Survey of Family Growth on self-reported pregnancy loss (miscarriage, stillbirth, ectopic pregnancy) among US women (15-44 years) who reported at least one pregnancy conceived during 1990-2011 that did not result in induced termination (n = 20 012 women; n = 42 526 pregnancies)...
October 20, 2017: Paediatric and Perinatal Epidemiology
https://www.readbyqxmd.com/read/28984372/adverse-maternal-and-birth-outcomes-in-women-admitted-to-hospital-for-hyperemesis-gravidarum-a-population-based-cohort-study
#2
Linda Fiaschi, Catherine Nelson-Piercy, Jack Gibson, Lisa Szatkowski, Laila J Tata
BACKGROUND: Evidence for risks of adverse maternal and birth outcomes in women with hyperemesis gravidarum (HG) is predominantly from small studies, unknown, or conflicting. METHODS: A population-based cohort study using secondary health care records (Hospital Episode Statistics covering all of England from 1997 to 2012) was used to calculate odds ratios (OR) with 99% confidence intervals (CI) for the association between HG hospital admission and adverse outcomes, adjusting for maternal and pregnancy confounders...
October 6, 2017: Paediatric and Perinatal Epidemiology
https://www.readbyqxmd.com/read/28984369/maternal-multivitamin-intake-plasma-folate-and-vitamin-b12-levels-and-autism-spectrum-disorder-risk-in-offspring
#3
Ramkripa Raghavan, Anne W Riley, Heather Volk, Deanna Caruso, Lynn Hironaka, Laura Sices, Xiumei Hong, Guoying Wang, Yuelong Ji, Martha Brucato, Anastacia Wahl, Tom Stivers, Colleen Pearson, Barry Zuckerman, Elizabeth A Stuart, Rebecca Landa, M Daniele Fallin, Xiaobin Wang
BACKGROUND: To examine the prospective association between multivitamin supplementation during pregnancy and biomarker measures of maternal plasma folate and vitamin B12 levels at birth and child's Autism Spectrum Disorder (ASD) risk. METHODS: This report included 1257 mother-child pairs, who were recruited at birth and prospectively followed through childhood at the Boston Medical Center. ASD was defined from diagnostic codes in electronic medical records. Maternal multivitamin supplementation was assessed via questionnaire interview; maternal plasma folate and B12 were measured from samples taken 2-3 days after birth...
October 6, 2017: Paediatric and Perinatal Epidemiology
https://www.readbyqxmd.com/read/28971498/agreement-between-maternal-report-and-medical-records-during-pregnancy-medications-for-rheumatoid-arthritis-and-asthma
#4
Kristin Palmsten, Avanthi Hulugalle, Gretchen Bandoli, Grace M Kuo, Shayda Ansari, Ronghui Xu, Christina D Chambers
BACKGROUND: There are limited data regarding the comparability of medication exposure information during pregnancy from maternal report and medical records, including for rheumatoid arthritis and asthma-related medications. METHODS: This study included pregnant women with rheumatoid arthritis (n = 216) and asthma (n = 172) enrolled in the MothertoBaby Pregnancy Studies (2009-2014). Women reported types and dates of medications used through semi-structured telephone interviews up to three times during pregnancy and once after delivery, and medical records were obtained...
October 3, 2017: Paediatric and Perinatal Epidemiology
https://www.readbyqxmd.com/read/28940632/parental-age-and-risk-of-infant-leukaemia-a-pooled-analysis
#5
Erin L Marcotte, Todd E Druley, Kimberly J Johnson, Michaela Richardson, Julie von Behren, Beth A Mueller, Susan Carozza, Colleen McLaughlin, Eric J Chow, Peggy Reynolds, Logan G Spector
BACKGROUND: Infant leukaemia (IL) is extremely rare with fewer than 150 cases occurring each year in the United States. Little is known about its causes. However, recent evidence supports a role of de novo mutations in IL aetiology. Parental age has been associated with several adverse outcomes in offspring, including childhood cancers. Given the role of older parental age in de novo mutations in offspring, we carried out an analysis of parental age and IL. METHODS: We evaluated the relationship between parental age and IL in a case-control study using registry data from New York, Minnesota, California, Texas, and Washington...
September 22, 2017: Paediatric and Perinatal Epidemiology
https://www.readbyqxmd.com/read/28940519/a-time-varying-covariate-approach-for-survival-analysis-of-paediatric-outcomes
#6
Jian Zhao, Yun Zhao, Andy H Lee, Colin W Binns
BACKGROUND: Conventional survival analysis is commonly applied in the analysis of time-to-event data in paediatric studies, where the exposure variables of interest are often treated as time-fixed. However, the values of these exposure variables can vary over time and time-fixed analysis may introduce time-dependent bias. METHODS: Time-dependent bias is illustrated graphically considering two scenarios in longitudinal study settings for paediatric time-to-event outcomes...
September 22, 2017: Paediatric and Perinatal Epidemiology
https://www.readbyqxmd.com/read/28913940/caesarean-birth-is-associated-with-both-maternal-and-paternal-origin-in-immigrants-in-sweden-a-population-based-study
#7
Sol P Juárez, Rhonda Small, Anders Hjern, Erica Schytt
BACKGROUND: To investigate the association between maternal country of birth and father's origin and unplanned and planned caesarean birth in Sweden. METHODS: Population-based register study including all singleton births in Sweden between 1999 and 2012 (n = 1 311 885). Multinomial regression was conducted to estimate odds ratios (OR) for unplanned and planned caesarean with 95% confidence intervals for migrant compared with Swedish-born women. Analyses were stratified by parity...
September 15, 2017: Paediatric and Perinatal Epidemiology
https://www.readbyqxmd.com/read/28913889/prevalence-and-contributors-to-low-grade-inflammation-in-three-u-s-populations-of-reproductive-age-women
#8
Lindsey A Sjaarda, Rose G Radin, Chandra Swanson, Daniel L Kuhr, Sunni L Mumford, Noya Galai, Robert M Silver, Jean Wactawski-Wende, Neil J Perkins, Enrique F Schisterman
BACKGROUND: Inflammation, measured by high-sensitivity C-reactive protein (hsCRP), is linked to adverse reproductive outcomes. However, prevalence and predictors of low-grade inflammation are poorly understood among reproductive age women. Therefore, the current aim was to characterize: (i) the prevalence of elevated hsCRP and (ii) whether the association of various demographic, anthropometric, life style, and metabolic characteristics with higher hsCRP varies across populations of reproductive age women with varying risk profiles for adverse reproductive outcomes...
September 15, 2017: Paediatric and Perinatal Epidemiology
https://www.readbyqxmd.com/read/28898931/what-kind-of-policies-for-fertility-treatment-would-improve-affordability-and-outcomes-for-individuals-and-the-public
#9
Joseph B Stanford
No abstract text is available yet for this article.
September 12, 2017: Paediatric and Perinatal Epidemiology
https://www.readbyqxmd.com/read/28898924/prevalence-of-autism-spectrum-disorders-with-and-without-intellectual-disability-by-gestational-age-at-birth-in-the-stockholm-youth-cohort-a-register-linkage-study
#10
Sherlly Xie, Hein Heuvelman, Cecilia Magnusson, Dheeraj Rai, Kristen Lyall, Craig J Newschaffer, Christina Dalman, Brian K Lee, Kathryn Abel
BACKGROUND: Preterm birth has been linked to increased risk of autism spectrum disorders (ASD), but how this risk changes with gestational age at birth has not been well characterised, especially with regard to co-occurring intellectual disability (ID). METHODS: Register-based cohort study of singleton births in 1984-2007 in Stockholm County, Sweden (N total: 480 728; n ASD: 10 025). We assessed overall and sex-specific, gestational week-specific prevalence estimates and risk ratios of ASD with and without ID...
September 12, 2017: Paediatric and Perinatal Epidemiology
https://www.readbyqxmd.com/read/28881463/a-family-based-study-of-carbon-monoxide-and-nitric-oxide-signalling-genes-and-preeclampsia
#11
Anna E Bauer, Christy L Avery, Min Shi, Clarice R Weinberg, Andrew F Olshan, Quaker E Harmon, Jingchun Luo, Jenny Yang, Tracy A Manuck, Michael C Wu, Nicholas Williams, Ralph McGinnis, Linda Morgan, Kari Klungsøyr, Lill Trogstad, Per Magnus, Stephanie M Engel
BACKGROUND: Preeclampsia is thought to originate during placentation, with incomplete remodelling and perfusion of the spiral arteries leading to reduced placental vascular capacity. Nitric oxide (NO) and carbon monoxide (CO) are powerful vasodilators that play a role in the placental vascular system. Although family clustering of preeclampsia has been observed, the existing genetic literature is limited by a failure to consider both mother and child. METHODS: We conducted a nested case-control study within the Norwegian Mother and Child Birth Cohort of 1545 case-pairs and 995 control-pairs from 2540 validated dyads (2011 complete pairs, 529 missing mother or child genotype)...
September 7, 2017: Paediatric and Perinatal Epidemiology
https://www.readbyqxmd.com/read/28881452/hypertensive-disorders-in-pregnancy-and-future-maternal%C3%A2-cardiovascular-disease-the-challenges-of-looking-beyond-first-pregnancy
#12
Lisa A DeRoo
No abstract text is available yet for this article.
September 7, 2017: Paediatric and Perinatal Epidemiology
https://www.readbyqxmd.com/read/28881395/long-standing-challenges-to-exposure-measurement-and-outcome-definitions-the-case-of-alcohol-and-autism-spectrum-disorder
#13
Sarah A Keim, Kelly W Sheppard
No abstract text is available yet for this article.
September 7, 2017: Paediatric and Perinatal Epidemiology
https://www.readbyqxmd.com/read/28881394/the-effect-of-vaccination-against-human-papillomavirus-on-fecundability
#14
Kathryn A McInerney, Elizabeth E Hatch, Amelia K Wesselink, Ellen M Mikkelsen, Kenneth J Rothman, Rebecca B Perkins, Lauren A Wise
BACKGROUND: The human papillomavirus (HPV) vaccine was developed to prevent infection with strains of HPV that cause cervical cancer. While HPV infection has been associated with reduced semen quality and lower pregnancy rates in some studies, no studies have examined the relationship between HPV vaccination and fecundability. We hypothesize that HPV prevention via vaccination will protect fecundity. METHODS: We analysed data from Pregnancy Study Online (PRESTO), a preconception cohort of North American pregnancy planners...
September 7, 2017: Paediatric and Perinatal Epidemiology
https://www.readbyqxmd.com/read/28881393/outcomes-of-gallstone-disease-during-pregnancy-a-population-based-data-linkage-study
#15
Ibinabo Ibiebele, Margaret Schnitzler, Tanya Nippita, Jane B Ford
BACKGROUND: Gallstone disease is a leading indication for non-obstetric abdominal surgery during pregnancy. There are limited whole population data on maternal and neonatal outcomes. This population-based study aims to describe the outcomes of gallstone disease during pregnancy in an Australian setting. METHODS: Linked hospital, birth, and mortality data for all women with singleton pregnancies in New South Wales, Australia, 2001-2012 were analysed. Exposure of interest was gallstone disease (acute biliary pancreatitis, gallstones with/without cholecystitis)...
September 7, 2017: Paediatric and Perinatal Epidemiology
https://www.readbyqxmd.com/read/28881390/prenatal-alcohol-exposure-in-relation-to-autism-spectrum-disorder-findings-from-the-study-to-explore-early-development-seed
#16
Alison B Singer, Arthur S Aylsworth, Christina Cordero, Lisa A Croen, Carolyn DiGuiseppi, M Daniele Fallin, Amy H Herring, Stephen R Hooper, Rebecca E Pretzel, Laura A Schieve, Gayle C Windham, Julie L Daniels
BACKGROUND: Prenatal alcohol exposure can affect neurodevelopment, but few studies have examined associations with autism spectrum disorder (ASD). METHODS: We assessed the association between maternal alcohol use and ASD in the Study to Explore Early Development, a multi-site case-control study of children born between September 2003 and August 2006 in the US Regression analyses included 684 children with research clinician-confirmed ASD, 869 children with non-ASD developmental delays or disorders (DDs), and 962 controls ascertained from the general population (POP)...
September 7, 2017: Paediatric and Perinatal Epidemiology
https://www.readbyqxmd.com/read/28869795/maternal-smoking-during-pregnancy-and-offspring-weight-gain-a-consideration-of-competing-explanations
#17
Edmond D Shenassa
No abstract text is available yet for this article.
September 4, 2017: Paediatric and Perinatal Epidemiology
https://www.readbyqxmd.com/read/28869773/antioxidant-consumption-is-associated-with-decreased-odds-of-congenital-limb-deficiencies
#18
Nelson D Pace, Tania A Desrosiers, Suzan L Carmichael, Gary M Shaw, Andrew F Olshan, Anna Maria Siega-Riz
BACKGROUND: Approximately 1 in 2000 infants is born with a limb deficiency in the US. Research has shown that women's periconceptional diet and use of vitamin supplements can affect risk of birth defects. We investigated whether maternal consumption of nutritional antioxidants was associated with occurrence of transverse limb deficiency (TLD) and longitudinal limb deficiencies (LLD). METHODS: We analysed case-control data from mothers and their singleton infants with TLD (n = 566), LLD (n = 339), or no malformation (controls; n = 9384) in the National Birth Defects Prevention Study (1997-2009)...
September 4, 2017: Paediatric and Perinatal Epidemiology
https://www.readbyqxmd.com/read/28841756/gastroschisis-in-europe-a-case-malformed-control-study-of-medication-and-maternal-illness-during-pregnancy-as-risk-factors
#19
Joanne E Given, Maria Loane, Ester Garne, Vera Nelen, Ingeborg Barisic, Hanitra Randrianaivo, Babak Khoshnood, Awi Wiesel, Anke Rissmann, Catherine Lynch, Amanda J Neville, Anna Pierini, Marian Bakker, Kari Klungsoyr, Anna Latos Bielenska, Clara Cavero-Carbonell, Marie-Claude Addor, Natalya Zymak-Zakutnya, David Tucker, Helen Dolk
BACKGROUND: Gastroschisis, a congenital anomaly of the abdomen, is associated with young maternal age and has increased in prevalence in many countries. Maternal illness and medication exposure are among environmental risk factors implicated in its aetiology. METHODS: A population-based case-malformed control study was conducted using data from 18 European congenital anomaly registries, with information on first trimester medication use, covering 8 million births 1995-2012...
August 25, 2017: Paediatric and Perinatal Epidemiology
https://www.readbyqxmd.com/read/28841751/air-pollution-who-is-at-risk
#20
Pauline Mendola
No abstract text is available yet for this article.
August 25, 2017: Paediatric and Perinatal Epidemiology
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