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Ophthalmology

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https://www.readbyqxmd.com/read/28732590/cost-utility-of-evaluation-for-posterior-vitreous-detachment-and-prophylaxis-of-retinal-detachment
#1
Nicolas A Yannuzzi, Jonathan S Chang, Gary C Brown, William E Smiddy
PURPOSE: To evaluate the costs and cost-utility of examination for posterior vitreous detachment (PVD) and treatment of associated pathology, and of managing various other peripheral retinal disorders to prevent retinal detachment (RD). DESIGN: A decision analysis model of cost-utility. PARTICIPANTS: There were no participants. METHODS: Published retrospective data on the natural course of PVD, retinal tears, and lattice degeneration were used to quantitate the visual benefits of examination and treatment...
July 18, 2017: Ophthalmology
https://www.readbyqxmd.com/read/28732589/accuracy-of-diagnostic-imaging-modalities-for-classifying-pediatric-eyes-as-papilledema-versus-pseudopapilledema
#2
Melinda Y Chang, Federico G Velez, Joseph L Demer, Laura Bonelli, Peter A Quiros, Anthony C Arnold, Alfredo A Sadun, Stacy L Pineles
PURPOSE: To identify the most accurate diagnostic imaging modality for classifying pediatric eyes as papilledema (PE) or pseudopapilledema (PPE). DESIGN: Prospective observational study. SUBJECTS: Nineteen children between the ages of 5 and 18 years were recruited. Five children (10 eyes) with PE, 11 children (19 eyes) with PPE owing to suspected buried optic disc drusen (ODD), and 3 children (6 eyes) with PPE owing to superficial ODD were included...
July 18, 2017: Ophthalmology
https://www.readbyqxmd.com/read/28728924/strabismus-measurements-with-novel-video-goggles
#3
Konrad P Weber, Daniel Rappoport, Muriel Dysli, Tanja Schmückle Meier, Guy B Marks, Christopher J Bockisch, Klara Landau, Hamish G MacDougall
PURPOSE: To assess the validity of a novel, simplified, noninvasive test for strabismus using video goggles. DESIGN: Cross-sectional method comparison study in which the new test, the strabismus video goggles, is compared with the existing reference standard, the Hess screen test. PARTICIPANTS: We studied 41 adult and child patients aged ≥6 years with ocular misalignment owing to congenital or acquired paralytic or comitant strabismus and 17 healthy volunteers...
July 17, 2017: Ophthalmology
https://www.readbyqxmd.com/read/28712657/prevalence-of-age-related-macular-degeneration-in-europe-the-past-and-the-future
#4
Johanna M Colijn, Gabriëlle H S Buitendijk, Elena Prokofyeva, Dalila Alves, Maria L Cachulo, Anthony P Khawaja, Audrey Cougnard-Gregoire, Bénédicte M J Merle, Christina Korb, Maja G Erke, Alain Bron, Eleftherios Anastasopoulos, Magda A Meester-Smoor, Tatiana Segato, Stefano Piermarocchi, Paulus T V M de Jong, Johannes R Vingerling, Fotis Topouzis, Catherine Creuzot-Garcher, Geir Bertelsen, Norbert Pfeiffer, Astrid E Fletcher, Paul J Foster, Rufino Silva, Jean-François Korobelnik, Cécile Delcourt, Caroline C W Klaver
PURPOSE: Age-related macular degeneration (AMD) is a frequent, complex disorder in elderly of European ancestry. Risk profiles and treatment options have changed considerably over the years, which may have affected disease prevalence and outcome. We determined the prevalence of early and late AMD in Europe from 1990 to 2013 using the European Eye Epidemiology (E3) consortium, and made projections for the future. DESIGN: Meta-analysis of prevalence data. PARTICIPANTS: A total of 42 080 individuals 40 years of age and older participating in 14 population-based cohorts from 10 countries in Europe...
July 14, 2017: Ophthalmology
https://www.readbyqxmd.com/read/28712656/treatments-for-ocular-adnexal-lymphoma-a-report-by-the-american-academy-of-ophthalmology
#5
Michael T Yen, Jurij R Bilyk, Edward J Wladis, Elizabeth A Bradley, Louise A Mawn
PURPOSE: To review the literature to determine the efficacy of available treatments for ocular adnexal lymphoma (OAL) and to evaluate the outcomes and complications of treatments in patients older than 13 years. METHODS: A literature search was conducted last in March 2017 in the PubMed and Cochrane Library databases for English-language original research investigations that evaluated treatment outcomes for OAL. The searches identified 307 unique citations, and 27 studies were selected according to the criteria outlined for this assessment...
July 13, 2017: Ophthalmology
https://www.readbyqxmd.com/read/28711218/significant-axial-elongation-with-minimal-change-in-refraction-in-3-to-6-year-old-chinese-preschoolers-the-shenzhen-kindergarten-eye-study
#6
Xinxing Guo, Min Fu, Xiaohu Ding, Ian G Morgan, Yangfa Zeng, Mingguang He
PURPOSE: To document the distribution of ocular biometry and to evaluate its associations with refraction in a group of Chinese preschoolers. DESIGN: Population-based cross-sectional study. PARTICIPANTS: A total of 1133 preschoolers 3 to 6 years of age from 8 representative kindergartens. METHODS: Biometric measurements including axial length (AL), anterior chamber depth (ACD), and corneal radius of curvature (CR) were obtained from partial-coherence laser interferometry (IOL Master; Carl Zeiss Meditec, Oberkochen, Germany) before cycloplegia...
July 13, 2017: Ophthalmology
https://www.readbyqxmd.com/read/28709702/clinical-and-morphologic-characteristics-of-mek-inhibitor-associated-retinopathy-differences-from-central-serous-chorioretinopathy
#7
Jasmine H Francis, Larissa A Habib, David H Abramson, Lawrence A Yannuzzi, Murk Heinemann, Mrinal M Gounder, Rachel N Grisham, Michael A Postow, Alexander N Shoushtari, Ping Chi, Neil H Segal, Rona Yaeger, Alan L Ho, Paul B Chapman, Federica Catalanotti
PURPOSE: To investigate the clinical and morphologic characteristics of serous retinal disturbances in patients taking mitogen-activated protein kinase kinase (MEK) inhibitors. PARTICIPANTS: A total of 313 fluid foci in 50 eyes of 25 patients receiving MEK inhibitors for treatment of their metastatic cancer, who had evidence of serous retinal detachments confirmed by optical coherence tomography (OCT). DESIGN: Single-center, retrospective cohort study...
July 12, 2017: Ophthalmology
https://www.readbyqxmd.com/read/28705429/disinfection-of-tonometers-a-report-by-the-american-academy-of-ophthalmology
#8
Anna K Junk, Philip P Chen, Shan C Lin, Kouros Nouri-Mahdavi, Sunita Radhakrishnan, Kuldev Singh, Teresa C Chen
OBJECTIVE: To examine the efficacy of various disinfection methods for reusable tonometer prisms in eye care and to highlight how disinfectants can damage tonometer tips and cause subsequent patient harm. METHODS: Literature searches were conducted last in October 2016 in the PubMed and the Cochrane Library databases for original research investigations. Reviews, non-English language articles, nonophthalmology articles, surveys, and case reports were excluded. RESULTS: The searches initially yielded 64 unique citations...
July 11, 2017: Ophthalmology
https://www.readbyqxmd.com/read/28689898/corticosteroid-related-adverse-events-systematically-increase-with-corticosteroid-dose-in-noninfectious-intermediate-posterior-or-panuveitis-post-hoc-analyses-from-the-visual-1-and-visual-2-trials
#9
Eric B Suhler, Jennifer E Thorne, Manish Mittal, Keith A Betts, Samir Tari, Anne Camez, Yanjun Bao, Avani Joshi
PURPOSE: Chronic use of corticosteroids for the treatment of uveitis has been linked with drug-associated toxicity and adverse events (AEs). This study examines the association between corticosteroid dosage and incidence rates of corticosteroid-related AEs. DESIGN: A post hoc analysis of the VISUAL-1 and VISUAL-2 placebo-controlled clinical trials. PARTICIPANTS: The clinical trials consisted of adults with active (VISUAL-1) and inactive (VISUAL-2) noninfectious intermediate, posterior, and panuveitis...
July 6, 2017: Ophthalmology
https://www.readbyqxmd.com/read/28689897/the-prevalence-and-causes-of-vision-loss-in-indigenous-and-non-indigenous-australians-the-national-eye-health-survey
#10
Joshua Foreman, Jing Xie, Stuart Keel, Peter van Wijngaarden, Sukhpal Singh Sandhu, Ghee Soon Ang, Jennifer Fan Gaskin, Jonathan Crowston, Rupert Bourne, Hugh R Taylor, Mohamed Dirani
PURPOSE: To conduct a nationwide survey on the prevalence and causes of vision loss in Indigenous and non-Indigenous Australians. DESIGN: Nationwide, cross-sectional, population-based survey. PARTICIPANTS: Indigenous Australians aged 40 years or older and non-Indigenous Australians aged 50 years and older. METHODS: Multistage random-cluster sampling was used to select 3098 non-Indigenous Australians and 1738 Indigenous Australians from 30 sites across 5 remoteness strata (response rate of 71...
July 6, 2017: Ophthalmology
https://www.readbyqxmd.com/read/28676282/anterior-segment-ocular-findings-and-microphthalmia-in-congenital-zika-syndrome
#11
Bruno de Paula Freitas, Andrea Zin, Albert Ko, Maurício Maia, Camila V Ventura, Rubens Belfort
No abstract text is available yet for this article.
July 1, 2017: Ophthalmology
https://www.readbyqxmd.com/read/28676281/chronic-kidney-disease-and-eye-diseases-the-beijing-eye-study
#12
Jost B Jonas, Ya Xing Wang, Wen Bin Wei, Jie Xu, Qi Sheng You, Liang Xu
No abstract text is available yet for this article.
July 1, 2017: Ophthalmology
https://www.readbyqxmd.com/read/28676280/evidence-based-criteria-for-assessment-of-visual-field-reliability
#13
Jithin Yohannan, Jiangxia Wang, Jamie Brown, Balwantray C Chauhan, Michael V Boland, David S Friedman, Pradeep Y Ramulu
PURPOSE: Assess the impact of false-positives (FP), false-negatives (FN), fixation losses (FL), and test duration (TD) on visual field (VF) reliability at different stages of glaucoma severity. DESIGN: Retrospective. PARTICIPANTS: A total of 10 262 VFs from 1538 eyes of 909 subjects with suspect or manifest glaucoma and ≥5 VF examinations. METHODS: Predicted mean deviation (MD) was calculated with multilevel modeling of longitudinal data...
July 1, 2017: Ophthalmology
https://www.readbyqxmd.com/read/28676279/projection-resolved-optical-coherence-tomography-angiography-of-macular-retinal-circulation-in-glaucoma
#14
Hana L Takusagawa, Liang Liu, Kelly N Ma, Yali Jia, Simon S Gao, Miao Zhang, Beth Edmunds, Mansi Parikh, Shandiz Tehrani, John C Morrison, David Huang
PURPOSE: To detect macular perfusion defects in glaucoma using projection-resolved optical coherence tomography (OCT) angiography. DESIGN: Prospective observation study. PARTICIPANTS: A total of 30 perimetric glaucoma and 30 age-matched normal participants were included. METHODS: One eye of each participant was imaged using 6 × 6-mm macular OCT angiography (OCTA) scan pattern by 70-kHz 840-nm spectral-domain OCT. Flow signal was calculated by the split-spectrum amplitude-decorrelation angiography algorithm...
July 1, 2017: Ophthalmology
https://www.readbyqxmd.com/read/28669492/atropine-for-the-prevention-of-myopia-progression-in-children-a-report-by-the-american-academy-of-ophthalmology
#15
Stacy L Pineles, Raymond T Kraker, Deborah K VanderVeen, Amy K Hutchinson, Jennifer A Galvin, Lorri B Wilson, Scott R Lambert
PURPOSE: To review the published literature on the efficacy of topical atropine for the prevention of myopic progression in children. METHODS: Literature searches were last conducted in December 2016 in the PubMed database with no date restrictions, but were limited to studies published in English, and in the Cochrane Library database without any restrictions. The combined searches yielded 98 citations, 23 of which were reviewed in full text. Of these, 17 articles were deemed appropriate for inclusion in this assessment and subsequently were assigned a level of evidence rating by the panel methodologist...
June 29, 2017: Ophthalmology
https://www.readbyqxmd.com/read/28655539/myopic-choroidal-neovascularization-review-guidance-and-consensus-statement-on-management
#16
Chui Ming Gemmy Cheung, Jennifer J Arnold, Frank G Holz, Kyu Hyung Park, Timothy Y Y Lai, Michael Larsen, Paul Mitchell, Kyoko Ohno-Matsui, Shih-Jen Chen, Sebastian Wolf, Tien Yin Wong
TOPIC: The aim of this article is to review and compile available information on the classification, pathophysiology, and clinical features of myopic choroidal neovascularization (CNV); to describe the latest data on the management of this disease; and to present guidance. CLINICAL RELEVANCE: In the United States, myopia affects approximately 34 million people (2010), and similar figures have been reported in Europe. Pathologic myopia (PM), a possible consequence of myopia, is estimated to affect up to 3% of the global population...
June 24, 2017: Ophthalmology
https://www.readbyqxmd.com/read/28655538/u-s-multicenter-clinical-trial-of-corneal-collagen-crosslinking-for-treatment-of-corneal-ectasia-after-refractive-surgery
#17
Peter S Hersh, R Doyle Stulting, David Muller, Daniel S Durrie, Rajesh K Rajpal
PURPOSE: To evaluate the safety and efficacy of corneal collagen crosslinking (CXL) for the treatment of corneal ectasia after laser refractive surgery. DESIGN: Prospective, randomized, multicenter, controlled clinical trial. PARTICIPANTS: One hundred seventy-nine subjects with corneal ectasia after previous refractive surgery. METHODS: The treatment group underwent standard CXL, and the sham control group received riboflavin alone without removal of the epithelium...
June 24, 2017: Ophthalmology
https://www.readbyqxmd.com/read/28655537/not-all-seeds-are-created-equal-seed-classification-is-predictive-of-outcomes-in%C3%A2-retinoblastoma
#18
Jesse L Berry, Mercy Bechtold, Sona Shah, Emily Zolfaghari, Mark Reid, Rima Jubran, Jonathan W Kim
OBJECTIVE: Intravitreal chemotherapy has emerged as an important modality for treating vitreous seeding in retinoblastoma. A classification system has been described as predictive of response to intravitreal melphalan (IVM) in patients treated predominantly with primary intra-arterial chemotherapy. The objective of this study is to evaluate the outcomes of retinoblastoma treated with intravenous chemotherapy and IVM as salvage for vitreous seeding, and further to determine whether vitreous seed classification (dust, spheres, cloud) is predictive of the total number and dose of IVM injections required for treatment in this cohort...
June 24, 2017: Ophthalmology
https://www.readbyqxmd.com/read/28651813/magnetic-oculomotor-prosthetics-for-acquired-nystagmus
#19
Parashkev Nachev, Geoff E Rose, David H Verity, Sanjay G Manohar, Kelly MacKenzie, Gill Adams, Maria Theodorou, Quentin A Pankhurst, Christopher Kennard
PURPOSE: Acquired nystagmus, a highly symptomatic consequence of damage to the substrates of oculomotor control, often is resistant to pharmacotherapy. Although heterogeneous in its neural cause, its expression is unified at the effector-the eye muscles themselves-where physical damping of the oscillation offers an alternative approach. Because direct surgical fixation would immobilize the globe, action at a distance is required to damp the oscillation at the point of fixation, allowing unhindered gaze shifts at other times...
June 23, 2017: Ophthalmology
https://www.readbyqxmd.com/read/28648381/clinical-phenotypes-of-poppers-maculopathy-and-their-links-to-visual-and-anatomic-recovery
#20
Laure B Van Bol, Rengin A Kurt, Pearse A Keane, Bishwanath Pal, Sobha Sivaprasad
No abstract text is available yet for this article.
June 22, 2017: Ophthalmology
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