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Ophthalmology

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https://www.readbyqxmd.com/read/30419298/durability-of-diabetic-retinopathy-improvement-with-as-needed-ranibizumab-open-label-extension-of-ride-and-rise-studies
#1
Jennifer K Sun, Pin-Wen Wang, Sarah Taylor, Zdenka Haskova
OBJECTIVE: To evaluate durability of diabetic retinopathy (DR) improvements after a change in ranibizumab dosing from monthly to individualized pro re nata (PRN) therapy. DESIGN: Pooled analysis of the open-label extension (OLE) of RIDE/RISE (NCT00473382/NCT00473330) patients with DR and diabetic macular edema (DME). PARTICIPANTS: Patients who completed 36-month participation in RIDE/RISE and entered the OLE. METHODS: In the RIDE/RISE studies, patients (N = 759) were randomized 1:1:1 to ranibizumab 0...
November 9, 2018: Ophthalmology
https://www.readbyqxmd.com/read/30419297/rhegmatogenous-retinal-detachment-in-children-clinical-factors-predictive-of-successful-surgical-repair
#2
Jesse M Smith, Laura T Ward, Justin H Townsend, Jiong Yan, Andrew M Hendrick, Blaine E Cribbs, Steven Yeh, Nieraj Jain, G Baker Hubbard
OBJECTIVE: To describe presenting clinical features and surgical techniques that are associated with successful surgical repair of pediatric rhegmatogenous retinal detachment (RRD). DESIGN: Retrospective interventional case series. SUBJECTS: 212 eyes of 191 patients, aged 0-18 years, undergoing surgical repair for RRD between 2001 and 2015 with a minimum follow up of 3 months. METHODS: Patients were divided into three age groups (0-6 years, 7-12 years, 13-18 years) and comparisons were made using bivariate and multivariable generalized estimating equation models...
November 9, 2018: Ophthalmology
https://www.readbyqxmd.com/read/30403988/24-hour-intraocular-pressure-control-with-fixed-dose-combination-brinzolamide-1-brimonidine-0-2-a-multicenter-randomized-trial
#3
Robert N Weinreb, Jason Bacharach, Robert D Fechtner, Malik Y Kahook, David Wirta, Steve Burmaster, Xiangyi Meng, Douglas A Hubatsch
PURPOSE: To determine the intraocular pressure (IOP)-lowering effect of fixed-combination brinzolamide 1%/brimonidine 0.2% (BBFC) over a 24-hour period. DESIGN: Prospective, multicenter, double-masked, parallel-group clinical trial conducted at 16 academic and non-academic sites in the USA. PARTICIPANTS: Subjects with open-angle glaucoma (OAG) or ocular hypertension (OHT) aged ≥18 years, with mean baseline IOP measurements in at least one eye of ≥21 and <28 mmHg...
November 4, 2018: Ophthalmology
https://www.readbyqxmd.com/read/30389424/the-arms2-a69s-polymorphism-is-associated-with-delayed-rod-mediated-dark-adaptation-in-eyes-at-risk-for-incident-age-related-macular-degeneration
#4
Robert F Mullins, Gerald McGwin, Karen Searcey, Mark E Clark, Elizabeth L Kennedy, Christine A Curcio, Edwin M Stone, Cynthia Owsley
OBJECTIVE: To examine the association between sequence variants in genetic risk factors for age-related macular degeneration (AMD), and delayed rod-mediated dark adaptation (RMDA), the first functional biomarker for incident AMD, in older adults with normal macular health and early AMD. DESIGN: Cross-sectional SUBJECTS: Older adults aged ≥60 years in normal macular health (defined as both eyes at step 1 on the Age-Related Eye Disease 9-step AMD classification system) and those with AMD in one or both eyes (defined as steps 2-9)...
October 30, 2018: Ophthalmology
https://www.readbyqxmd.com/read/30367884/effect-of-an-injectable-fluocinolone-acetonide-insert-on-recurrence-rates-in-noninfectious-uveitis-affecting-the-posterior-segment-12-month-results
#5
Glenn J Jaffe, Stephen Foster, Carlos Pavesio, Dario Paggiarino, Gerard E Riedel
OBJECTIVE: To assess the safety and efficacy of an intravitreal fluocinolone acetonide insert (FAi) to manage inflammation associated with noninfectious posterior uveitis. DESIGN: Multi-center, randomized, prospective, doubled-masked, sham-controlled, 3-year, phase 3 clinical trial. PARTICIPANTS: A total of 129 participants with recurrent noninfectious posterior uveitis were randomly assigned to FAi (N=87) or sham injection (N=42). The more severely affected eye in participants with bilateral disease was designated as the study eye...
October 24, 2018: Ophthalmology
https://www.readbyqxmd.com/read/30366800/blepharitis-preferred-practice-pattern%C3%A2
#6
Guillermo Amescua, Esen K Akpek, Marjan Farid, Francisco J Garcia-Ferrer, Amy Lin, Michelle K Rhee, Divya M Varu, David C Musch, Steven P Dunn, Francis S Mah
No abstract text is available yet for this article.
October 23, 2018: Ophthalmology
https://www.readbyqxmd.com/read/30366799/bacterial-keratitis-preferred-practice-pattern%C3%A2
#7
Amy Lin, Michelle K Rhee, Esen K Akpek, Guillermo Amescua, Marjan Farid, Francisco J Garcia-Ferrer, Divya M Varu, David C Musch, Steven P Dunn, Francis S Mah
No abstract text is available yet for this article.
October 23, 2018: Ophthalmology
https://www.readbyqxmd.com/read/30366798/dry-eye-syndrome-preferred-practice-pattern%C3%A2
#8
Esen K Akpek, Guillermo Amescua, Marjan Farid, Francisco J Garcia-Ferrer, Amy Lin, Michelle K Rhee, Divya M Varu, David C Musch, Steven P Dunn, Francis S Mah
No abstract text is available yet for this article.
October 23, 2018: Ophthalmology
https://www.readbyqxmd.com/read/30366797/conjunctivitis-preferred-practice-pattern%C3%A2
#9
Divya M Varu, Michelle K Rhee, Esen K Akpek, Guillermo Amescua, Marjan Farid, Francisco J Garcia-Ferrer, Amy Lin, David C Musch, Francis S Mah, Steven P Dunn
No abstract text is available yet for this article.
October 23, 2018: Ophthalmology
https://www.readbyqxmd.com/read/30366796/telemetric-intraocular-pressure-monitoring-after-boston-keratoprosthesis-surgery
#10
Philip Enders, Jonathan Hall, Marco Bornhauser, Kaweh Mansouri, Lebriz Altay, Stefan Schrader, Thomas S Dietlein, Bjoern O Bachmann, Thomas Neuhann, Claus Cursiefen
No abstract text is available yet for this article.
October 23, 2018: Ophthalmology
https://www.readbyqxmd.com/read/30366795/corneal-edema-opacification-preferred-practice-pattern%C3%A2
#11
Marjan Farid, Michelle K Rhee, Esen K Akpek, Guillermo Amescua, Francisco J Garcia-Ferrer, Amy Lin, Divya M Varu, David C Musch, Francis S Mah, Steven P Dunn
No abstract text is available yet for this article.
October 23, 2018: Ophthalmology
https://www.readbyqxmd.com/read/30366794/corneal-ectasia-preferred-practice-pattern%C3%A2
#12
Francisco J Garcia-Ferrer, Esen K Akpek, Guillermo Amescua, Marjan Farid, Amy Lin, Michelle K Rhee, Divya M Varu, David C Musch, Francis S Mah, Steven P Dunn
No abstract text is available yet for this article.
October 23, 2018: Ophthalmology
https://www.readbyqxmd.com/read/30352226/a-randomized-trial-of-binocular-dig-rush-game-treatment-for-amblyopia-in-children-aged-7-to-12-years-of-age
#13
Jonathan M Holmes, Ruth E Manny, Elizabeth L Lazar, Eileen E Birch, Krista R Kelly, Allison I Summers, Stacy R Martinson, Aparna Raghuram, Jeffrey D Colburn, Christine Law, Justin D Marsh, Derek P Bitner, Raymond T Kraker, David K Wallace
PURPOSE: To compare visual acuity (VA) improvement in children aged 7 to 12 years with amblyopia treated with a binocular iPad® game plus continued spectacle correction versus continued spectacle correction alone. DESIGN: Multi-center randomized clinical trial PARTICIPANTS: One hundred thirty-eight participants aged 7 to 12 years with amblyopia (33 to 72 letters, i.e., approximately 20/200 to 20/40) resulting from strabismus, anisometropia, or both. Participants were required to have at least 16 weeks of optical treatment in spectacles if needed or demonstrate no improvement in amblyopic-eye visual acuity (VA) for at least 8 weeks prior to enrollment...
October 20, 2018: Ophthalmology
https://www.readbyqxmd.com/read/30352225/genetic-architecture-of-primary-open-angle-glaucoma-in-individuals-of-african-descent-the-african-descent-glaucoma-evaluation-study-adages-iii
#14
Kent D Taylor, Xiuqing Guo, Linda M Zangwill, Jeffrey M Liebmann, Christopher A Girkin, Robert M Feldman, Harvey Dubiner, Yang Hai, Brian C Samuels, Joseph F Panarelli, John P Mitchell, Lama A Al-Aswad, Sung Chul Park, Celso Tello, Jeremy Cotliar, Rajendra Bansal, Paul A Sidoti, George A Cioffi, Dana Blumberg, Robert Ritch, Nicholas P Bell, Lauren S Blieden, Garvin Davis, Felipe A Medeiros, Swapan K Das, Jasmin Divers, Carl D Langefeld, Nicholette D Palmer, Barry I Freedman, Donald W Bowden, Maggie C Y Ng, Yii-Der Ida Chen, Radha Ayyagari, Jerome I Rotter, Robert N Weinreb
OBJECTIVE: Find genetic contributions to glaucoma in African Americans. DESIGN: Cross-sectional, case-control study. PARTICIPANTS: 1875 POAG cases and 1709 controls, self-identified as African Descent (AD), from the African Descent and Glaucoma Evaluation Study (ADAGESIII) and Wake Forest School of Medicine. METHODS: MegaChip genotypes were imputed to Thousand Genomes data. Association of SNPs with POAG and advanced POAG was tested by linear mixed model correcting for relatedness and population stratification...
October 20, 2018: Ophthalmology
https://www.readbyqxmd.com/read/30343940/reply
#15
LETTER
Robert Kersten, M Reza Vagefi, George B Bartley
No abstract text is available yet for this article.
October 18, 2018: Ophthalmology
https://www.readbyqxmd.com/read/30343939/re-adrean-et-al-consistent-long-term-therapy-of-neovascular-age-related-macular-degeneration-managed-by-50-or-more-anti-vegf-injections-using-a-treat-extend-stop-protocol-ophthalmology-2018-125-1047-1053
#16
LETTER
https://www.readbyqxmd.com/read/30343938/reply
#17
LETTER
Sean D Adrean, Siyang Chaili, Hema Ramkumar, Ash Pirouz, Scott Grant
No abstract text is available yet for this article.
October 18, 2018: Ophthalmology
https://www.readbyqxmd.com/read/30343937/re-young-et-al-conservatively-treated-orbital-blowout-fractures-spontaneous-radiologic-improvement-ophthalmology-2018-125-938-944
#18
LETTER
Enis D Kocak, Jonathan K Kam, Anthony J Hall
No abstract text is available yet for this article.
October 18, 2018: Ophthalmology
https://www.readbyqxmd.com/read/30343936/reply
#19
LETTER
Aaron Lee, Paul Taylor, Jayashree Kalpathy-Cramer, Adnan Tufail
No abstract text is available yet for this article.
October 18, 2018: Ophthalmology
https://www.readbyqxmd.com/read/30343935/re-lee-et-al-machine-learning-has-arrived-ophthalmology-2017-124-1726-1728
#20
LETTER
Nikitha Murali, Susan Forster
No abstract text is available yet for this article.
October 18, 2018: Ophthalmology
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