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Occupational and Environmental Medicine

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https://www.readbyqxmd.com/read/28526715/cancer-incidence-in-female-laboratory-employees-extended-follow-up-of-a-swedish-cohort-study
#1
Per Gustavsson, Tomas Andersson, Annika Gustavsson, Christina Reuterwall
OBJECTIVES: Work in chemical laboratories is associated with exposure to chemicals, of which some are known or suspected carcinogens. A cohort study of laboratory workers in Stockholm followed until 1992 showed an excess of hematolymphatic malignancies in chemical laboratories and an excess of breast cancer among women working for more than 10 years in such laboratories. The follow-up of this cohort has now been extended by 20 years. METHODS: The cohort comprised 2245 female laboratory workers who are employed for >1 year from 1950 to 1989...
May 19, 2017: Occupational and Environmental Medicine
https://www.readbyqxmd.com/read/28515054/longitudinal-decline-in-lung-function-among-older-construction-workers
#2
John M Dement, Laura S Welch, Knut Ringen, Kim Cranford, Patricia Quinn
BACKGROUND: Occupational exposures to vapours, gasses, dusts and fumes (VGDF) and chest X-ray abnormalities by the International Labour Office (ILO) classification system are associated with reduced lung function, with the majority of published studies being cross-sectional. We examined the effects of VGDF exposures, as well as ILO parenchymal changes, pleural plaque and diffuse pleural thickening (DPT) on reduction in lung function in a longitudinal study. METHODS: Chest radiographs and spirometry for 3150 ageing construction workers enrolled in a medical screening programme with a baseline and at least one follow-up examination were studied...
May 17, 2017: Occupational and Environmental Medicine
https://www.readbyqxmd.com/read/28501798/dose-time-response-association-between-occupational-asbestos-exposure-and-pleural-mesothelioma
#3
Aude Lacourt, Emilie Lévêque, Elie Guichard, Anabelle Gilg Soit Ilg, Marie-Pierre Sylvestre, Karen Leffondré
OBJECTIVES: Early occupational exposure to asbestos has been shown to be associated with an increased risk of pleural mesothelioma (PM), which suggests that the timing of exposure might play a role in the dose-response relationship. However, none studies has evaluated the relative impact of increasing the annual intensity of occupational exposure to asbestos at each time of the whole exposure history. Yet such evaluation would allow the comparison of the risks of PM associated with different longitudinal profiles of occupational exposure to asbestos...
May 13, 2017: Occupational and Environmental Medicine
https://www.readbyqxmd.com/read/28490663/quantitative-estimated-exposure-to-vinyl-chloride-and-risk-of-angiosarcoma-of-the-liver-and-hepatocellular-cancer-in-the-us-industry-wide-vinyl-chloride-cohort-mortality-update-through-2013
#4
Kenneth A Mundt, Linda D Dell, Lori Crawford, Alexa E Gallagher
OBJECTIVE: To evaluate mortality risks of angiosarcoma of the liver (ASL), primary hepatocellular carcinoma (HCC) and other cancers among 9951 men employed between 1942 and 1972 at 35 US vinyl chloride (VC) or polyvinyl chloride plants followed for mortality through 31 December 2013. METHODS: SMR and time-dependent Cox proportional hazards analyses were used to evaluate mortality risks by cumulative VC exposure. RESULTS: Liver cancer mortality was elevated (SMR=2...
May 10, 2017: Occupational and Environmental Medicine
https://www.readbyqxmd.com/read/28490662/occupational-exposure-to-endotoxins-and-lung-cancer-risk-results-of-the-icare-study
#5
Soumaya Ben Khedher, Monica Neri, Florence Guida, Mireille Matrat, Sylvie Cenée, Marie Sanchez, Gwenn Menvielle, Florence Molinié, Danièle Luce, Isabelle Stücker
OBJECTIVES: To investigate the role of occupational exposure to endotoxins in lung cancer in a French population-based case-control study (ICARE (Investigation of occupational and environmental causes of respiratory cancers)). METHODS: Detailed information was collected on the occupational history and smoking habits from 2926 patients with histologically confirmed lung cancer and 3555 matched controls. We evaluated each subject's endotoxin exposure after cross referencing International Standard Classification of Occupations (ISCO) codes (for job tasks) and Nomenclature d'Activités Françaises (NAF) codes (for activity sectors)...
May 10, 2017: Occupational and Environmental Medicine
https://www.readbyqxmd.com/read/28490661/surgery-for-subacromial-impingement-syndrome-in-relation-to-occupational-exposures-lifestyle-factors-and-diabetes-mellitus-a-nationwide-nested-case-control-study
#6
Annett Dalbøge, Poul Frost, Johan Hviid Andersen, Susanne Wulff Svendsen
OBJECTIVES: To estimate the risk of surgery for subacromial impingement syndrome (SIS) in relation to occupational exposures, lifestyle factors and diabetes mellitus. METHODS: We conducted a case-control study nested in a register-based cohort study of the Danish working population. For each of 3000 first-time cases of surgery for SIS, two age-matched and sex-matched controls were drawn. Cases and controls received a questionnaire on job history and other factors...
May 10, 2017: Occupational and Environmental Medicine
https://www.readbyqxmd.com/read/28483972/work-disability-prevention-should-we-focus-on-high-body-weights-or-heavy-physical-workload
#7
EDITORIAL
Cameron A Mustard
No abstract text is available yet for this article.
May 8, 2017: Occupational and Environmental Medicine
https://www.readbyqxmd.com/read/28483971/association-of-household-cleaning-agents-and-disinfectants-with-asthma-in-young-german-adults
#8
Tobias Weinmann, Jessica Gerlich, Sabine Heinrich, Dennis Nowak, Erika von Mutius, Christian Vogelberg, Jon Genuneit, Stefanie Lanzinger, Saba Al-Khadra, Tina Lohse, Irina Motoc, Viola Walter, Katja Radon
OBJECTIVES: We scrutinised the association of private use of household sprays and disinfectants with asthma incidence in young adults in the transition from school to working life. METHODS: Between 2007 and 2009,2051 young adults aged 19-24 years living in two major German cities took part in the Study on Occupational Allergy Risks II. Self-reported exposure to household sprays and disinfectants was characterised according to a composite score for frequency of use as no use (score=0), low use (score between 1 and the median), medium use (score between the median and the 90th percentile) and high use (score above the 90th percentile)...
May 8, 2017: Occupational and Environmental Medicine
https://www.readbyqxmd.com/read/28468931/pleural-abnormalities-in-the-framingham-heart-study-prevalence-and-ct-image-features
#9
Tetsuro Araki, Masahiro Yanagawa, Fangui Jenny Sun, Josée Dupuis, Mizuki Nishino, Yoshitake Yamada, George R Washko, David C Christiani, Noriyuki Tomiyama, George T O'Connor, Gary M Hunninghake, Hiroto Hatabu
BACKGROUND: The prevalence of pleural abnormalities in the general population is an epidemiologically important index of asbestos exposure, which has not been investigated since a radiography-based study in 1980. METHODS: We examined 2633 chest CT scans (mean 59.2 years, 50% female) from the Framingham Heart Study (FHS) for the presence and image characteristics of pleural plaques and diffuse pleural thickening. Demographics and pulmonary function were stratified by the presence of pleural abnormalities in association with interstitial lung abnormalities...
May 3, 2017: Occupational and Environmental Medicine
https://www.readbyqxmd.com/read/28468930/need-for-methods-to-measuring-capacity-and-incapacity-from-working-life-to-old-age
#10
EDITORIAL
Clas-Håkan Nygård, Taina Rantanen
No abstract text is available yet for this article.
May 3, 2017: Occupational and Environmental Medicine
https://www.readbyqxmd.com/read/28456763/female-white-collar-workers-remain-at-higher-risk-of-breast-cancer-after-adjustments-for-individual-risk-factors-related-to-reproduction-and-lifestyle
#11
Cecilia Kullberg, Jenny Selander, Maria Albin, Signe Borgquist, Jonas Manjer, Per Gustavsson
OBJECTIVES: The aim was to investigate the variation in risk of breast cancer between occupational groups with a focus on white-collar and blue-collar workers and to investigate to what extent the differences were explained by risk factors related to reproduction and lifestyle. METHODS: Between 1991 and 1996, 14 119 women born between 1923 and 1950 and residents of Malmö, Sweden, were included in this cohort study. Individual data on risk factors (eg, age, parity, age at first child, months of breast feeding per child, hormonal replacement therapy, physical activity, alcohol consumption, smoking, height and body mass index) and occupational history were assessed using a questionnaire...
April 29, 2017: Occupational and Environmental Medicine
https://www.readbyqxmd.com/read/28442544/effects-of-aircraft-noise-exposure-on-saliva-cortisol-near-airports-in-france
#12
Marie Lefèvre, Marie-Christine Carlier, Patricia Champelovier, Jacques Lambert, Bernard Laumon, Anne-Sophie Evrard
BACKGROUND: Saliva cortisol is a possible marker of noise-induced stress and could then mediate the relation observed between exposure to aircraft or road traffic noise and cardiovascular diseases. However, the association between transportation noise and cortisol levels is still unclear. The objective of the study was to investigate the variability of saliva cortisol concentration as an indicator of disturbed hypothalamus-pituitary-adrenal (HPA) axis regulation in relation to long-term aircraft noise exposure...
April 25, 2017: Occupational and Environmental Medicine
https://www.readbyqxmd.com/read/28442543/effect-of-informal-employment-on-the-relationship-between-psychosocial-work-risk-factors-and-musculoskeletal-pain-in-central-american-workers
#13
David Gimeno Ruiz de Porras, Marianela Rojas Garbanzo, Aurora Aragón, Lino Carmenate-Milián, Fernando G Benavides
INTRODUCTION: The constant increase on the psychosocial demands experienced at work seems to contribute to the increase in health problems such as musculoskeletal pain (MSP). This association may be especially important in low-income and middle-income countries, where there is a large proportion of informal workers among whom there is little research. We analysed the association between psychosocial work risk factors and MSP among formal and informal workers using the First Central American Survey of Working Conditions and Health...
April 25, 2017: Occupational and Environmental Medicine
https://www.readbyqxmd.com/read/28438788/associations-between-persistent-organic-pollutants-type-2-diabetes-diabetic-nephropathy-and-mortality
#14
Brian A Grice, Robert G Nelson, Desmond E Williams, William C Knowler, Clinton Mason, Robert L Hanson, Kai McKeever Bullard, Meda E Pavkov
OBJECTIVE: Relationships were examined between persistent organic pollutants (POPs) and incident type 2 diabetes, end-stage renal disease (ESRD) and mortality. METHODS: In a nested case-control study, 300 persons without diabetes had baseline examinations between 1969 and 1974; 149 developed diabetes (cases) and 151 remained non-diabetic (controls) during 8.0 and 23.1 years of follow-up, respectively. POPs were measured at baseline. ORs for diabetes were computed by logistic regression analysis...
April 24, 2017: Occupational and Environmental Medicine
https://www.readbyqxmd.com/read/28438787/mortality-from-cancer-and-other-causes-among-italian-chrysotile-asbestos-miners
#15
Enrico Pira, Canzio Romano, Francesca Donato, Claudio Pelucchi, Carlo La Vecchia, Paolo Boffetta
OBJECTIVE: To investigate the long-term mortality of a cohort of Italian asbestos miners. METHODS: The cohort included 1056 men employed in a chrysotile mine between 1930 and 1990, who were followed up during 1946-2014, for a total of 37 471 person-years of observation. Expected deaths and SMRs were computed using national and local (after 1980, when available) reference. RESULTS: A total of 294 (27.8%) subjects were alive and at the end of follow-up, 722 (68...
April 24, 2017: Occupational and Environmental Medicine
https://www.readbyqxmd.com/read/28416643/can-serum-cytokine-profile-discriminate-irritant-induced-and-allergen-induced-symptoms-a-cross-sectional-study-in-workers-mostly-exposed-to-laboratory-animals
#16
Muriel Lemaire, Anne Oppliger, Philipp Hotz, Jean-Christophe Renauld, Julia Braun, Marion Maggi, Fabio Barresi, Peter Schmid-Grendelmeier, François Huaux, Holger Dressel
BACKGROUND: In workers exposed mostly to laboratory animals (LA), symptoms may be due to irritants or allergens. Correct aetiological diagnosis is important for health surveillance. OBJECTIVES: This study aims to test whether work-related (WR) allergen-induced symptoms are associated with a cytokine profile distinct from that due to irritants. METHODS: In a cross-sectional study (n=114), WR respiratory and/or skin symptoms were assessed through a standardised clinical examination and sensitisation to rat and/or mouse allergen determined by serum immunoglobulin E...
April 17, 2017: Occupational and Environmental Medicine
https://www.readbyqxmd.com/read/28416642/estimating-the-burden-of-occupational-cancer-assessing-bias-and-uncertainty
#17
Sally Hutchings, Lesley Rushton
BACKGROUND AND OBJECTIVES: We aimed to estimate credibility intervals for the British occupational cancer burden to account for bias uncertainty, using a method adapted from Greenland's Monte Carlo sensitivity analysis. METHODS: The attributable fraction (AF) methodology used for our cancer burden estimates requires risk estimates and population proportions exposed for each agent/cancer pair. Sources of bias operating on AF estimator components include non-portability of risk estimates, inadequate models, inaccurate data including unknown cancer latency and employment turnover and compromises in using the available estimators...
April 17, 2017: Occupational and Environmental Medicine
https://www.readbyqxmd.com/read/28408656/is-job-rotation-effective-for-prevention-of-work-related-musculoskeletal-disorders-and-sick-leave
#18
EDITORIAL
Charlotte Diana Nørregaard Rasmussen
No abstract text is available yet for this article.
April 13, 2017: Occupational and Environmental Medicine
https://www.readbyqxmd.com/read/28408655/military-small-arms-fire-in-association-with-acute-decrements-in-lung-function
#19
Anne Katrine Borander, Øyvind Albert Voie, Kjetil Longva, Tor Erik Danielsen, Svein Grahnstedt, Leiv Sandvik, Johny Kongerud, Liv Ingunn Bjoner Sikkeland
OBJECTIVE: After introduction of unleaded ammunition, Norwegian Armed Forces received reports of acute respiratory symptoms in soldiers after exposure to fumes from firing the standard weapon, HK416. The aim of the present study was to examine lung function before and after exposure to fumes from HK416 in a double-blinded standardised study design using three different types of ammunition. METHODS: Fifty-four healthy, non-smoking male volunteers (19-62 years) fired the weapons for 60 min with either leaded, unleaded or 'modified' unleaded ammunition...
April 13, 2017: Occupational and Environmental Medicine
https://www.readbyqxmd.com/read/28408654/radiographic-disease-progression-in-contemporary-us-coal-miners-with-progressive-massive-fibrosis
#20
A Scott Laney, David John Blackley, Cara N Halldin
INTRODUCTION: Among contemporary US coal miners, there has been an increase in the prevalence and severity of pneumoconiosis, including its advanced form progressive massive fibrosis (PMF). We examine radiographic progression in Coal Workers' Health Surveillance Program (CWHSP) participants. METHODS: CWHSP participants with a final determination of PMF during 1 January 2000-1 October 2016 with at least one prior radiograph in the system were included. We characterised demographics, participation and progression patterns...
April 13, 2017: Occupational and Environmental Medicine
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