journal
MENU ▼
Read by QxMD icon Read
search

Neurology

journal
https://www.readbyqxmd.com/read/29222127/unilateral-periodic-pupillary-constriction-causing-alternating-anisocoria
#1
Erin C Conrad, Imran Jivraj, Randy Kardon, Grant T Liu
No abstract text is available yet for this article.
December 8, 2017: Neurology
https://www.readbyqxmd.com/read/29222126/autoimmune-crmp5-neuropathy-phenotype-and-outcome-defined-from-105-cases
#2
Divyanshu Dubey, Vanda A Lennon, Avi Gadoth, Sean J Pittock, Eoin P Flanagan, John E Schmeling, Andrew McKeon, Christopher J Klein
OBJECTIVE: To establish the phenotype and clinical outcomes of collapsin response-mediator protein-5 (CRMP5) autoimmune neuropathy in comparison with anti-neuronal nuclear antibody type 1 (ANNA1)-immunoglobulin G (IgG) neuropathy. METHODS: Patients with CRMP5-IgG and/or ANNA1-IgGs were identified in our service-line testing, and medical records were reviewed. RESULTS: One hundred five patients with CRMP5-IgG neuropathy (88% smokers; 69% having cancer, most commonly small cell lung cancer [75%]) were identified and compared to 51 patients with ANNA1-IgG neuropathy, 27 with coexisting CRMP5-IgG...
December 8, 2017: Neurology
https://www.readbyqxmd.com/read/29212830/multicenter-evaluation-of-neurofilaments-in-early-symptom-onset-amyotrophic-lateral-sclerosis
#3
Emily Feneberg, Patrick Oeckl, Petra Steinacker, Federico Verde, Christian Barro, Philip Van Damme, Elizabeth Gray, Julian Grosskreutz, Claude Jardel, Jens Kuhle, Sonja Koerner, Foudil Lamari, Maria Del Mar Amador, Benjamin Mayer, Claudia Morelli, Petra Muckova, Susanne Petri, Koen Poesen, Joost Raaphorst, François Salachas, Vincenzo Silani, Beatrice Stubendorff, Martin R Turner, Marcel M Verbeek, Jochen H Weishaupt, Patrick Weydt, Albert C Ludolph, Markus Otto
OBJECTIVE: To examine neurofilament (Nf) concentrations according to symptom onset and clinical diagnostic certainty categories of amyotrophic lateral sclerosis (ALS). METHODS: We measured Nf light chain (NfL) and phosphorylated Nf heavy chain (pNfH) CSF and NfL serum levels in patients with ALS with first symptom onset ≤6 months (n = 54) or >6 months (n = 135) from sampling, and patients with other neurologic diseases, differential diagnoses of a motor neuron disease (MND mimics), and other MND variants to determine the diagnostic accuracy in patients with ALS with early symptom onset...
December 6, 2017: Neurology
https://www.readbyqxmd.com/read/29212829/pml-in-a-person-with-multiple-sclerosis-is-teriflunomide-the-felon
#4
Lorena Lorefice, Giuseppe Fenu, Simonetta Gerevini, Jessica Frau, Giancarlo Coghe, Maria Antonietta Barracciu, Franco Contu, Maria Giovanna Marrosu, Eleonora Cocco
No abstract text is available yet for this article.
December 6, 2017: Neurology
https://www.readbyqxmd.com/read/29212828/detecting-anxiety-in-individuals-with-parkinson-disease-a-systematic-review
#5
Bria Mele, Jayna Holroyd-Leduc, Eric E Smith, Tamara Pringsheim, Zahinoor Ismail, Zahra Goodarzi
OBJECTIVE: To examine diagnostic accuracy of anxiety detection tools compared with a gold standard in outpatient settings among adults with Parkinson disease (PD). METHODS: A systematic review was conducted. MEDLINE, EMABASE, PsycINFO, and Cochrane Database of Systematic Reviews were searched to April 7, 2017. Prevalence of anxiety and diagnostic accuracy measures including sensitivity, specificity, and likelihood ratios were gathered. Pooled prevalence of anxiety was calculated using Mantel-Haenszel-weighted DerSimonian and Laird models...
December 6, 2017: Neurology
https://www.readbyqxmd.com/read/29212827/diet-quality-is-associated-with-disability-and-symptom-severity-in-multiple-sclerosis
#6
Kathryn C Fitzgerald, Tuula Tyry, Amber Salter, Stacey S Cofield, Gary Cutter, Robert Fox, Ruth Ann Marrie
OBJECTIVE: To assess the association between diet quality and intake of specific foods with disability and symptom severity in people with multiple sclerosis (MS). METHODS: In 2015, participants in the North American Research Committee on MS (NARCOMS) Registry completed a dietary screener questionnaire that estimates intake of fruits, vegetables and legumes, whole grains, added sugars, and red/processed meats. We constructed an overall diet quality score for each individual based on these food groups; higher scores denoted a healthier diet...
December 6, 2017: Neurology
https://www.readbyqxmd.com/read/29212826/diet-in-multiple-sclerosis-science-takes-a-seat-at-the-table
#7
EDITORIAL
James F Sumowski, Gavin V McDonnell, Dennis Bourdette
No abstract text is available yet for this article.
December 6, 2017: Neurology
https://www.readbyqxmd.com/read/29196581/increased-midlife-triglycerides-predict-brain-%C3%AE-amyloid-and-tau-pathology-20-years-later
#8
Katarina Nägga, Anna-Märta Gustavsson, Erik Stomrud, Daniel Lindqvist, Danielle van Westen, Kaj Blennow, Henrik Zetterberg, Olle Melander, Oskar Hansson
OBJECTIVE: To evaluate the effect of midlife lipid levels on Alzheimer brain pathology 20 years later in cognitively normal elderly individuals. METHODS: This is a longitudinal cohort study of 318 cognitively normal individuals with data on fasting lipid levels at midlife (mean age 54 years). Presence of β-amyloid (Aβ) and tau pathologies 20 years later (mean age 73 years) were detected by quantifying Alzheimer disease (AD) biomarkers in CSF. In a subset (n = 134), Aβ (18F-flutemetamol) PET was also performed...
December 1, 2017: Neurology
https://www.readbyqxmd.com/read/29196580/sex-disparities-in-access-to-caregiving-in-parkinson-disease
#9
Nabila Dahodwala, Krunal Shah, Ying He, Samuel S Wu, Peter Schmidt, Fernando Cubillos, Allison W Willis
OBJECTIVE: To compare access to caregiving between men and women with Parkinson disease (PD). METHODS: This was a cross-sectional and longitudinal study among participants with PD enrolled in the National Parkinson Foundation Parkinson's Outcomes Project from 2009 to 2014 at 21 international sites. The primary outcome measures were presence of a caregiver at the baseline visit, caregiver burden as measured by the Multidimensional Caregiver Strain Index (MCSI) at baseline, and time to first paid caregiver...
December 1, 2017: Neurology
https://www.readbyqxmd.com/read/29196579/clinical-and-molecular-characterization-of-kcnt1-related-severe-early-onset-epilepsy
#10
Amy McTague, Umesh Nair, Sony Malhotra, Esther Meyer, Natalie Trump, Elena V Gazina, Apostolos Papandreou, Adeline Ngoh, Sally Ackermann, Gautam Ambegaonkar, Richard Appleton, Archana Desurkar, Christin Eltze, Rachel Kneen, Ajith V Kumar, Karine Lascelles, Tara Montgomery, Venkateswaran Ramesh, Rajib Samanta, Richard H Scott, Jeen Tan, William Whitehouse, Annapurna Poduri, Ingrid E Scheffer, W K Kling Chong, J Helen Cross, Maya Topf, Steven Petrou, Manju A Kurian
OBJECTIVE: To characterize the phenotypic spectrum, molecular genetic findings, and functional consequences of pathogenic variants in early-onset KCNT1 epilepsy. METHODS: We identified a cohort of 31 patients with epilepsy of infancy with migrating focal seizures (EIMFS) and screened for variants in KCNT1 using direct Sanger sequencing, a multiple-gene next-generation sequencing panel, and whole-exome sequencing. Additional patients with non-EIMFS early-onset epilepsy in whom we identified KCNT1 variants on local diagnostic multiple gene panel testing were also included...
December 1, 2017: Neurology
https://www.readbyqxmd.com/read/29196578/precision-therapy-for-epilepsy-due-to-kcnt1-mutations-a-randomized-trial-of-oral-quinidine
#11
Saul A Mullen, Patrick W Carney, Annie Roten, Michael Ching, Paul A Lightfoot, Leonid Churilov, Umesh Nair, Melody Li, Samuel F Berkovic, Steven Petrou, Ingrid E Scheffer
OBJECTIVE: To evaluate quinidine as a precision therapy for severe epilepsy due to gain of function mutations in the potassium channel gene KCNT1. METHODS: A single-center, inpatient, order-randomized, blinded, placebo-controlled, crossover trial of oral quinidine included 6 patients with severe autosomal dominant nocturnal frontal lobe epilepsy (ADNFLE) due to KCNT1 mutation. Order was block randomized and blinded. Four-day treatment blocks were used with a 2-day washout between...
December 1, 2017: Neurology
https://www.readbyqxmd.com/read/29196577/improving-the-costing-of-informal-caregiving-in-neurologic-populations
#12
Jill I Cameron
No abstract text is available yet for this article.
December 1, 2017: Neurology
https://www.readbyqxmd.com/read/29196576/apathy-is-associated-with-incident-dementia-in-community-dwelling-older-people
#13
Jan Willem van Dalen, Lennard L Van Wanrooij, Eric P Moll van Charante, Edo Richard, Willem A van Gool
OBJECTIVE: To assess whether apathy and depressive symptoms are independently associated with incident dementia during 6-year follow-up in a prospective observational population-based cohort study. METHODS: Participants were community-dwelling older people in the Prevention of Dementia by Intensive Vascular Care trial, aged 70-78 years, without dementia at baseline. Apathy and depressive symptoms were measured using the 15-item Geriatric Depression Scale (GDS-15)...
December 1, 2017: Neurology
https://www.readbyqxmd.com/read/29196575/pitfalls-in-developing-precision-medicine-for-genetic-epilepsy
#14
EDITORIAL
Kimford J Meador, Cheolsu Shin
No abstract text is available yet for this article.
December 1, 2017: Neurology
https://www.readbyqxmd.com/read/29196574/clinical-biomarkers-differentiate-myelitis-from-vascular-and-other-causes-of-myelopathy
#15
Paula Barreras, Kathryn C Fitzgerald, Maureen A Mealy, Jorge A Jimenez, Daniel Becker, Scott D Newsome, Michael Levy, Philippe Gailloud, Carlos A Pardo
OBJECTIVE: To assess the predictive value of the initial clinical and paraclinical features in the differentiation of inflammatory myelopathies from other causes of myelopathy in patients with initial diagnosis of transverse myelitis (TM). METHODS: We analyzed the clinical presentation, spinal cord MRI, and CSF features in a cohort of 457 patients referred to a specialized myelopathy center with the presumptive diagnosis of TM. After evaluation, the myelopathies were classified as inflammatory, ischemic/stroke, arteriovenous malformations/fistulas, spondylotic, or other...
December 1, 2017: Neurology
https://www.readbyqxmd.com/read/29196573/costs-of-informal-nursing-care-for-patients-with-neurologic-disorders-a-systematic-review
#16
REVIEW
Freya Diederich, Hans-Helmut König, Claudia Mietzner, Christian Brettschneider
OBJECTIVE: To systematically review the economic burden of informal nursing care (INC), often called informal care, caused by multiple sclerosis (MS), Parkinson disease (PD), and epilepsy, with special attention to disease severity. METHODS: We systematically searched MEDLINE, PsycINFO, and NHS Economic Evaluation Database for articles on the cost of illness of the diseases specified. Title, abstract, and full-text review were conducted in duplicate by 2 researchers...
December 1, 2017: Neurology
https://www.readbyqxmd.com/read/29187518/neurofascin-antibodies-in-autoimmune-genetic-and-idiopathic-neuropathies
#17
Elisabeth Burnor, Li Yang, Hao Zhou, Kristina R Patterson, Colin Quinn, Mary M Reilly, Alexander M Rossor, Steven S Scherer, Eric Lancaster
OBJECTIVE: To measure the frequency, persistence, isoform specificity, and clinical correlates of neurofascin antibodies in patients with peripheral neuropathies. METHODS: We studied cohorts of patients with Guillain-Barre syndrome (GBS) or chronic inflammatory demyelinating polyneuropathy (CIDP) (n = 59), genetic neuropathy (n = 111), and idiopathic neuropathy (n = 43) for immunoglobulin (Ig) G and IgM responses to 3 neurofascin (NF) isoforms (NF140, NF155, and NF186) using cell-based assays...
November 29, 2017: Neurology
https://www.readbyqxmd.com/read/29187517/-pinball-intrusions-in-spinocerebellar-ataxia-type-3
#18
João Lemos, Ana Novo, Cristina Duque, João Castelhano, Eric Eggenberger, Cristina Januário
No abstract text is available yet for this article.
November 29, 2017: Neurology
https://www.readbyqxmd.com/read/29150540/increased-florbetapir-binding-in-the-temporal-neocortex-from-age-20-to-60-years
#19
Julie Gonneaud, Eider M Arenaza-Urquijo, Florence Mézenge, Brigitte Landeau, Malo Gaubert, Alexandre Bejanin, Robin de Flores, Miranka Wirth, Clémence Tomadesso, Géraldine Poisnel, Ahmed Abbas, Béatrice Desgranges, Gaël Chételat
OBJECTIVE: To improve our understanding of early β-amyloid (Aβ) accumulation processes using florbetapir-PET scan in 20- to 60-year-old individuals. METHODS: Seventy-six cognitively normal individuals aged 20 to 60 years, 57 cognitively normal older individuals (61-84 years old), and 70 patients with mild cognitive impairment or probable Alzheimer disease (AD) underwent a florbetapir-PET scan. Images were spatially normalized and scaled using the whole cerebellum...
November 17, 2017: Neurology
https://www.readbyqxmd.com/read/29142090/virtual-reality-training-for-upper-extremity-in-subacute-stroke-virtues-a-multicenter-rct
#20
Iris Brunner, Jan Sture Skouen, Håkon Hofstad, Jörg Aßmus, Frank Becker, Anne-Marthe Sanders, Hanne Pallesen, Lola Qvist Kristensen, Marc Michielsen, Liselot Thijs, Geert Verheyden
OBJECTIVE: To compare the effectiveness of upper extremity virtual reality rehabilitation training (VR) to time-matched conventional training (CT) in the subacute phase after stroke. METHODS: In this randomized, controlled, single-blind phase III multicenter trial, 120 participants with upper extremity motor impairment within 12 weeks after stroke were consecutively included at 5 rehabilitation institutions. Participants were randomized to either VR or CT as an adjunct to standard rehabilitation and stratified according to mild to moderate or severe hand paresis, defined as ≥20 degrees wrist and 10 degrees finger extension or less, respectively...
November 15, 2017: Neurology
journal
journal
20202
1
2
Fetch more papers »
Fetching more papers... Fetching...
Read by QxMD. Sign in or create an account to discover new knowledge that matter to you.
Remove bar
Read by QxMD icon Read
×

Search Tips

Use Boolean operators: AND/OR

diabetic AND foot
diabetes OR diabetic

Exclude a word using the 'minus' sign

Virchow -triad

Use Parentheses

water AND (cup OR glass)

Add an asterisk (*) at end of a word to include word stems

Neuro* will search for Neurology, Neuroscientist, Neurological, and so on

Use quotes to search for an exact phrase

"primary prevention of cancer"
(heart or cardiac or cardio*) AND arrest -"American Heart Association"