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Neurology

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https://www.readbyqxmd.com/read/28615437/chance-juxtapositions-and-un-biased-methods-in-science-more-efficient-at-inefficiency
#1
EDITORIAL
Nina F Schor
No abstract text is available yet for this article.
June 14, 2017: Neurology
https://www.readbyqxmd.com/read/28615436/hospital-safety-among-neurologic-patients-a-population-based-cohort-study-of-adverse-events
#2
Khara M Sauro, Hude Quan, Khokan C Sikdar, Peter Faris, Nathalie Jette
OBJECTIVE: To examine the frequency and type of adverse events (AEs) experienced by neurologic patients in hospital. METHODS: This population-based, retrospective cohort study used hospital discharge abstract data for children and adults admitted to hospital from 2009 to 2015 with 1 of 9 neurologic conditions (Alzheimer disease and related dementia, brain tumor, epilepsy, motor neuron disease, multiple sclerosis, parkinsonism/Parkinson disease, spinal cord injury, traumatic brain injury, and stroke)...
June 14, 2017: Neurology
https://www.readbyqxmd.com/read/28615435/the-virtual-neurologist
#3
E Ray Dorsey
No abstract text is available yet for this article.
June 14, 2017: Neurology
https://www.readbyqxmd.com/read/28615434/a-randomized-trial-of-telemedicine-efficacy-and-safety-for-nonacute-headaches
#4
Kai I Müller, Karl B Alstadhaug, Svein I Bekkelund
OBJECTIVE: To evaluate long-term treatment efficacy and safety of one-time telemedicine consultations for nonacute headaches. METHODS: We randomized, allocated, and consulted nonacute headache patients via telemedicine (n = 200) or in a traditional manner (n = 202) in a noninferiority trial. Efficacy endpoints, assessed by questionnaires at 3 and 12 months, included change from baseline in Headache Impact Test-6 (HIT-6) (primary endpoint) and pain intensity (visual analogue scale [VAS]) (secondary endpoint)...
June 14, 2017: Neurology
https://www.readbyqxmd.com/read/28615433/disease-progression-in-c9orf72-mutation-carriers
#5
Mary K Floeter, Bryan J Traynor, Jennifer Farren, Laura E Braun, Michael Tierney, Edythe A Wiggs, Tianxia Wu
OBJECTIVE: To assess changes in 3 clinical measures, the Revised ALS Functional Rating Scale (ALSFRS-R), letter fluency, and Frontal Behavioral Inventory (FBI), over time in C9orf72 mutation carriers (C9+) with varied clinical phenotypes. METHODS: Thirty-four unrelated participants with mutations in C9orf72 were enrolled in a prospective natural history study. Participants were classified as asymptomatic, amyotrophic lateral sclerosis (ALS), ALS-familial frontotemporal dementia (FTD), or behavioral-variant FTD by clinical diagnostic criteria...
June 14, 2017: Neurology
https://www.readbyqxmd.com/read/28615432/dento-corneal-aberrant-regeneration-as-evidence-of-v2-innervation-of-the-inferior-human-cornea
#6
Anand Bery, J Alexander Fraser
No abstract text is available yet for this article.
June 14, 2017: Neurology
https://www.readbyqxmd.com/read/28615431/chronic-headache-what-s-in-a-name
#7
EDITORIAL
Mark A Louter, Thomas N Ward, Gisela M Terwindt
No abstract text is available yet for this article.
June 14, 2017: Neurology
https://www.readbyqxmd.com/read/28615430/characterization-of-patients-with-longstanding-idiopathic-rem-sleep-behavior-disorder
#8
Alex Iranzo, Ambra Stefani, Monica Serradell, Maria Jose Martí, Francisco Lomeña, Philipp Mahlknecht, Heike Stockner, Carles Gaig, Ana Fernández-Arcos, Werner Poewe, Eduard Tolosa, Birgit Högl, Joan Santamaria
OBJECTIVE: To evaluate the presence of prodromal markers of Parkinson disease (PD) in patients with longstanding idiopathic REM sleep behavior disorder (IRBD), a small subgroup of individuals with IRBD with long-term follow-up thought not to be at risk of developing PD. METHODS: Demographic, clinical, and neuroimaging markers of PD were evaluated in 20 patients with polysomnographic-confirmed long-standing IRBD and in 32 matched controls. RESULTS: Patients were 16 men and 4 women with mean age of 72...
June 14, 2017: Neurology
https://www.readbyqxmd.com/read/28615429/diagnostic-algorithm-for-relapsing-acquired-demyelinating-syndromes-in-children
#9
Yael Hacohen, Kshitij Mankad, W K Chong, Frederik Barkhof, Angela Vincent, Ming Lim, Evangeline Wassmer, Olga Ciccarelli, Cheryl Hemingway
OBJECTIVE: To establish whether children with relapsing acquired demyelinating syndromes (RDS) and myelin oligodendrocyte glycoprotein antibodies (MOG-Ab) show distinctive clinical and radiologic features and to generate a diagnostic algorithm for the main RDS for clinical use. METHODS: A panel reviewed the clinical characteristics, MOG-Ab and aquaporin-4 (AQP4) Ab, intrathecal oligoclonal bands, and Epstein-Barr virus serology results of 110 children with RDS. A neuroradiologist blinded to the diagnosis scored the MRI scans...
June 14, 2017: Neurology
https://www.readbyqxmd.com/read/28615428/increased-rate-of-venous-thrombosis-may-be-associated-with-inpatient-dihydroergotamine-treatment
#10
Amy R Tso, Irene R Patniyot, Amy A Gelfand, Peter J Goadsby
OBJECTIVE: To review whether the incidence of catheter-associated venous thromboses was higher in patients receiving IV dihydroergotamine compared to lidocaine. METHODS: We retrospectively reviewed all admissions at the University of California, San Francisco Headache Center from February 25, 2008, through October 31, 2014, for age, sex, diagnosis, aura, treatment dose, type of IV line used, days with line, superficial (SVT) or deep venous thrombosis (DVT), and pulmonary embolism (PE)...
June 14, 2017: Neurology
https://www.readbyqxmd.com/read/28615427/acute-flaccid-myelitis-and-enterovirus-d68-d%C3%A3-j%C3%A3-vu-all-over-again
#11
EDITORIAL
Max Wiznitzer, Avindra Nath
No abstract text is available yet for this article.
June 14, 2017: Neurology
https://www.readbyqxmd.com/read/28615426/modulation-of-intrinsic-resting-state-fmri-networks-in-women-with-chronic-migraine
#12
X Michelle Androulakis, Kaitlin Krebs, B Lee Peterlin, Tianming Zhang, Nasim Maleki, Souvik Sen, Chris Rorden, Priyantha Herath
OBJECTIVE: To evaluate the intrinsic resting functional connectivity of the default mode network (DMN), salience network (SN), and central executive network (CEN) network in women with chronic migraine (CM), and whether clinical features are associated with such abnormalities. METHODS: We analyzed resting-state connectivity in 29 women with CM as compared to age- and sex-matched controls. Relationships between clinical characteristics and changes in targeted networks connectivity were evaluated using a multivariate linear regression model...
June 14, 2017: Neurology
https://www.readbyqxmd.com/read/28615425/epilepsy-associated-long-term-mortality-after-aneurysmal-subarachnoid-hemorrhage
#13
Jukka Huttunen, Antti Lindgren, Mitja I Kurki, Terhi Huttunen, Juhana Frösen, Timo Koivisto, Mikael von Und Zu Fraunberg, Arto Immonen, Juha E Jääskeläinen, Reetta Kälviäinen
OBJECTIVE: To elucidate the epilepsy-associated causes of death and subsequent excess long-term mortality among 12-month survivors of subarachnoid hemorrhage from saccular intracranial aneurysm (SIA-SAH). METHODS: The Kuopio SIA Database (kuopioneurosurgery.fi) includes all SIA-SAH patients admitted to the Kuopio University Hospital from its defined catchment population in Eastern Finland. The study cohort consists of 779 patients, admitted from 1995 to 2007, who were alive at 12 months after SIA-SAH...
June 14, 2017: Neurology
https://www.readbyqxmd.com/read/28615424/epilepsy-and-mortality-after-aneurysmal-subarachnoid-hemorrhage
#14
EDITORIAL
Adil Harroud, Amy Z Crepeau
No abstract text is available yet for this article.
June 14, 2017: Neurology
https://www.readbyqxmd.com/read/28615423/diagnosis-of-dwi-negative-acute-ischemic-stroke-a-meta-analysis
#15
Brian L Edlow, Shelley Hurwitz, Jonathan A Edlow
OBJECTIVE: To determine the prevalence of diffusion-weighted imaging (DWI)-negative acute ischemic stroke (AIS) and to identify clinical characteristics of patients with DWI-negative AIS. METHODS: We systematically searched PubMed and Ovid/MEDLINE for relevant studies between 1992, the year that the DWI sequence entered clinical practice, and 2016. Studies were included based upon enrollment of consecutive patients presenting with a clinical diagnosis of AIS prior to imaging...
June 14, 2017: Neurology
https://www.readbyqxmd.com/read/28615422/prognostic-factors-for-chronic-headache-a-systematic-review
#16
REVIEW
Katrin Probyn, Hannah Bowers, Fiona Caldwell, Dipesh Mistry, Martin Underwood, Manjit Matharu, Tamar Pincus
OBJECTIVE: To identify predictors of prognosis and trial outcomes in prospective studies of people with chronic headache. METHODS: This was a systematic review of published literature in peer-reviewed journals. We included (1) randomized controlled trials (RCTs) of interventions for chronic headache that reported subgroup analyses and (2) prospective cohort studies, published in English, since 1980. Participants included adults with chronic headache (including chronic headache, chronic migraine, and chronic tension-type headache with or without medication overuse headache)...
June 14, 2017: Neurology
https://www.readbyqxmd.com/read/28615421/outcomes-of-colorado-children-with-acute-flaccid-myelitis-at-1-year
#17
Jan A Martin, Kevin Messacar, Michele L Yang, John A Maloney, Jennifer Lindwall, Terri Carry, Patricia Kenyon, Stefan H Sillau, Joyce Oleszek, Kenneth L Tyler, Samuel R Dominguez, Teri L Schreiner
OBJECTIVE: We describe long-term functional, neurodiagnostic, and psychosocial outcomes of a cohort of 12 children from Colorado diagnosed with acute flaccid myelitis (AFM) in 2014. METHODS: Children were assessed every 3 months for 1 year or until clinical resolution. Assessments included neurologic examination, MRI, EMG/nerve conduction studies (NCS), functional measures (Assisting Hand Assessment, Hammersmith Functional Motor Scale), and Patient-Reported Outcomes Measurement Information System questionnaires...
June 14, 2017: Neurology
https://www.readbyqxmd.com/read/28615420/insulin-resistance-among-obese-middle-aged-is-associated-with-decreased-cerebrovascular-reactivity
#18
Olivia H Frosch, Po Lai Yau, Ricardo S Osorio, Henry Rusinek, Pippa Storey, Antonio Convit
OBJECTIVE: To evaluate differences in cerebrovascular reactivity (CVR) to mild hypercapnia in obese/overweight individuals with and without insulin resistance (IR) compared to comparable lean controls. METHODS: A total of 60 cognitively normal participants (20 lean controls and 24 obese/overweight individuals with and 16 without IR) were evaluated using a high spatial resolution arterial spin labeling MRI technique at rest and during mild hypercapnia. We analyzed group differences in CVR in cerebral cortex and ascertained the relationships between CVR, IR, and body mass index (BMI)...
June 14, 2017: Neurology
https://www.readbyqxmd.com/read/28600462/failure-of-alemtuzumab-therapy-to-control-mog-encephalomyelitis
#19
Brigitte Wildemann, Sven Jarius, Alexander Schwarz, Ricarda Diem, Andrea Viehöver, Stefan Hähnel, Markus Reindl, Mirjam Korporal-Kuhnke
No abstract text is available yet for this article.
June 9, 2017: Neurology
https://www.readbyqxmd.com/read/28600461/cerebrovascular-disease-affects-brain-structural-integrity-long-before-clinically-overt-strokes
#20
EDITORIAL
David S Knopman, Babak Hooshmand
No abstract text is available yet for this article.
June 9, 2017: Neurology
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