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Nature Reviews. Clinical Oncology

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https://www.readbyqxmd.com/read/27922046/lung-cancer-liquid-biopsy-of-sclc-chemosensitivity
#1
David Killock
No abstract text is available yet for this article.
December 6, 2016: Nature Reviews. Clinical Oncology
https://www.readbyqxmd.com/read/27922045/head-and-neck-cancer-in-2016-a-watershed-year-for-improvements-in-treatment
#2
Alain P Algazi, Jennifer R Grandis
No abstract text is available yet for this article.
December 6, 2016: Nature Reviews. Clinical Oncology
https://www.readbyqxmd.com/read/27922044/from-tumour-heterogeneity-to-advances-in-precision-treatment-of-colorectal-cancer
#3
REVIEW
Cornelis J A Punt, Miriam Koopman, Louis Vermeulen
In recent years, the high heterogeneity of colorectal cancer (CRC) has become evident. Hence, biomarkers need to be developed that enable the stratification of patients with CRC into different prognostic subgroups and in relation to response to therapies, according to the distinctive tumour biology. Currently, only RAS-mutation status is used routinely as a negative predictive marker to avoid treatment with anti-EGFR agents in patients with metastatic CRC, and mismatch-repair status can guide the use of adjuvant chemotherapy in patients with early stage colon cancer...
December 6, 2016: Nature Reviews. Clinical Oncology
https://www.readbyqxmd.com/read/27922043/breast-cancer-paloma-2-hope-beyond-the-threshold
#4
Diana Romero
No abstract text is available yet for this article.
December 6, 2016: Nature Reviews. Clinical Oncology
https://www.readbyqxmd.com/read/27922042/neuroendocrine-tumours-in-2016-defining-rules-for-increasingly-personalized-treatments
#5
Massimo Falconi, Stefano Partelli
No abstract text is available yet for this article.
December 6, 2016: Nature Reviews. Clinical Oncology
https://www.readbyqxmd.com/read/27898067/the-need-for-multidisciplinarity-in-specialist-training-to-optimize-future-patient-care
#6
REVIEW
Alison C Tree, Victoria Harding, Aneel Bhangu, Venkatesh Krishnasamy, Dion Morton, Justin Stebbing, Bradford J Wood, Ricky A Sharma
Harmonious interactions between radiation, medical, interventional and surgical oncologists, as well as other members of multidisciplinary teams, are essential for the optimization of patient care in oncology. This multidisciplinary approach is particularly important in the current landscape, in which standard-of-care approaches to cancer treatment are evolving towards highly targeted treatments, precise image guidance and personalized cancer therapy. Herein, we highlight the importance of multidisciplinarity and interdisciplinarity at all levels of clinical oncology training...
November 29, 2016: Nature Reviews. Clinical Oncology
https://www.readbyqxmd.com/read/27898066/targeted-therapies-widening-the-treatment-net
#7
Lisa Hutchinson
No abstract text is available yet for this article.
November 29, 2016: Nature Reviews. Clinical Oncology
https://www.readbyqxmd.com/read/27898065/diagnosis-improved-diagnosis-therapy-and-outcomes-for-patients-with-cup
#8
F Anthony Greco
No abstract text is available yet for this article.
November 29, 2016: Nature Reviews. Clinical Oncology
https://www.readbyqxmd.com/read/27898064/palliative-care-lemonade-from-lemons-exploring-the-results-of-the-voice-study
#9
Nathan Cherny
No abstract text is available yet for this article.
November 29, 2016: Nature Reviews. Clinical Oncology
https://www.readbyqxmd.com/read/27874064/prostate-cancer-screening-and-treatment-where-do-we-go-from-here
#10
Fred Saad
No abstract text is available yet for this article.
November 22, 2016: Nature Reviews. Clinical Oncology
https://www.readbyqxmd.com/read/27874063/cns-cancer-tracing-stem-cells-in-oligodendroglioma
#11
Diana Romero
No abstract text is available yet for this article.
November 22, 2016: Nature Reviews. Clinical Oncology
https://www.readbyqxmd.com/read/27874062/systemic-perioperative-management-of-muscle-invasive-bladder-cancer-and-future-horizons
#12
REVIEW
Samuel A Funt, Jonathan E Rosenberg
Many patients diagnosed with muscle-invasive bladder cancer (MIBC) will develop distant metastatic disease. Over the past three decades, perioperative cisplatin-based chemotherapy has been investigated for its ability to reduce the number of deaths from bladder cancer. Insufficient evidence is available to fully support the use of such chemotherapy in the adjuvant setting; however, neoadjuvant cisplatin-based combination chemotherapy has become a standard of care for eligible patients based on the improved disease-specific and overall survival demonstrated in two randomized phase III trials, compared with surgery alone...
November 22, 2016: Nature Reviews. Clinical Oncology
https://www.readbyqxmd.com/read/27874061/strategies-to-avoid-treatment-induced-lineage-crisis-in-advanced-prostate-cancer
#13
REVIEW
Guilhem Roubaud, Bobby C Liaw, William K Oh, David J Mulholland
The increasing potency of therapies that target the androgen receptor (AR) signalling axis has correlated with a rise in the proportion of patients with prostate cancer harbouring an adaptive phenotype, termed treatment-induced lineage crisis. This phenotype is characterized by features that include soft-tissue metastasis and/or resistance to standard anticancer therapies. Potent anticancer treatments might force cancer cells to evolve and develop alternative cell lineages that are resistant to primary therapies, a mechanism similar to the generation of multidrug- resistant microorganisms after continued antibiotic use...
November 22, 2016: Nature Reviews. Clinical Oncology
https://www.readbyqxmd.com/read/27845767/activating-autophagy-to-potentiate-immunogenic-chemotherapy-and-radiation-therapy
#14
REVIEW
Lorenzo Galluzzi, José Manuel Bravo-San Pedro, Sandra Demaria, Silvia Chiara Formenti, Guido Kroemer
Autophagy is fundamental to the maintenance of intracellular homeostasis in virtually all human cells. Accordingly, defective autophagy predisposes healthy cells to undergoing malignant transformation. By contrast, malignant cells are able to harness autophagy to thrive, despite adverse microenvironmental conditions, and to resist therapeutic challenges. Thus, inhibition of autophagy has been proposed as a strategy to kill cancer cells or sensitize them to therapy; however, autophagy is also critical for optimal immune function, and mediates cell-extrinsic homeostatic effects owing to its central role in danger signalling by neoplastic cells responding to immunogenic chemotherapy and/or radiation therapy...
November 15, 2016: Nature Reviews. Clinical Oncology
https://www.readbyqxmd.com/read/27845348/lung-cancer-local-therapy-global-benefits
#15
David Killock
No abstract text is available yet for this article.
November 15, 2016: Nature Reviews. Clinical Oncology
https://www.readbyqxmd.com/read/27824048/genetics-new-paediatric-glioblastoma-treatment-option
#16
Lisa Hutchinson
No abstract text is available yet for this article.
November 8, 2016: Nature Reviews. Clinical Oncology
https://www.readbyqxmd.com/read/27824047/lung-cancer-best-supportive-care-a-reasonable-option-for-patients-with-brain-metastases
#17
Dirk Rades, Steven E Schild
No abstract text is available yet for this article.
November 8, 2016: Nature Reviews. Clinical Oncology
https://www.readbyqxmd.com/read/27824046/gastrointestinal-cancer-keeping-afloat-with-new-combination
#18
Diana Romero
No abstract text is available yet for this article.
November 8, 2016: Nature Reviews. Clinical Oncology
https://www.readbyqxmd.com/read/27805631/immunotherapy-more-gain-less-pain
#19
Lisa Hutchinson
No abstract text is available yet for this article.
November 2, 2016: Nature Reviews. Clinical Oncology
https://www.readbyqxmd.com/read/27805630/haematological-cancer-free-light-chains-should-be-monitored-in-blood
#20
Peter Sidaway
No abstract text is available yet for this article.
November 2, 2016: Nature Reviews. Clinical Oncology
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