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Magnetic Resonance in Medicine: Official Journal of the Society of Magnetic Resonance in Medicine

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https://www.readbyqxmd.com/read/29457287/zero-te-based-pseudo-ct-image-conversion-in-the-head-and-its-application-in-pet-mr-attenuation-correction-and-mr-guided-radiation-therapy-planning
#1
Florian Wiesinger, Mikael Bylund, Jaewon Yang, Sandeep Kaushik, Dattesh Shanbhag, Sangtae Ahn, Joakim H Jonsson, Josef A Lundman, Thomas Hope, Tufve Nyholm, Peder Larson, Cristina Cozzini
PURPOSE: To describe a method for converting Zero TE (ZTE) MR images into X-ray attenuation information in the form of pseudo-CT images and demonstrate its performance for (1) attenuation correction (AC) in PET/MR and (2) dose planning in MR-guided radiation therapy planning (RTP). METHODS: Proton density-weighted ZTE images were acquired as input for MR-based pseudo-CT conversion, providing (1) efficient capture of short-lived bone signals, (2) flat soft-tissue contrast, and (3) fast and robust 3D MR imaging...
February 18, 2018: Magnetic Resonance in Medicine: Official Journal of the Society of Magnetic Resonance in Medicine
https://www.readbyqxmd.com/read/29451329/high-spatiotemporal-resolution-bssfp-imaging-of-hyperpolarized-1-13-c-pyruvate-and-1-13-c-lactate-with-spectral-suppression-of-alanine-and-pyruvate-hydrate
#2
Eugene Milshteyn, Cornelius von Morze, Jeremy W Gordon, Zihan Zhu, Peder E Z Larson, Daniel B Vigneron
PURPOSE: The balanced steady-state free precession (bSSFP) acquisition enables high spatiotemporal resolution for hyperpolarized 13 C MRI at 3T but is limited by spectral contamination from adjacent resonances. The purpose of this study was to develop a framework for in vivo dynamic high resolution imaging of hyperpolarized [1- 13 C]pyruvate and [1- 13 C]lactate generated in vivo at 3T by simplifying the spectrum through the use of selective suppression pulses. METHODS: Spectral suppression pulses were incorporated into the bSSFP sequence for suppression of [1- 13 C]alanine and [1- 13 C]pyruvate-hydrate signals, leaving only the pyruvate and lactate resonances...
February 16, 2018: Magnetic Resonance in Medicine: Official Journal of the Society of Magnetic Resonance in Medicine
https://www.readbyqxmd.com/read/29446149/distinction-of-the-gaba-2-29-ppm-resonance-using-triple-refocusing-at-3-t-in-vivo
#3
Vivek Tiwari, Zhongxu An, Yiming Wang, Changho Choi
PURPOSE: To develop 1 H MR spectroscopy that provides distinction of γ-aminobutyric acid (GABA) signal at 3 T in vivo. METHODS: Triple-refocusing was tailored at 3 T, with numerical simulations and phantom validation, for distinction of the GABA 2.29-ppm resonance from the neighboring glutamate resonance. The optimization was performed on the inter-RF pulse time delays and the duration and carrier frequency of a non-slice-selective RF pulse. The optimized triple refocusing was tested in multiple regions in 6 healthy subjects, including hippocampus...
February 14, 2018: Magnetic Resonance in Medicine: Official Journal of the Society of Magnetic Resonance in Medicine
https://www.readbyqxmd.com/read/29446127/whole-body-mri-for-metastatic-cancer-detection-using-t-2-weighted-imaging-with-fat-and-fluid-suppression
#4
Xinzeng Wang, Ali Pirasteh, James Brugarolas, Neil M Rofsky, Robert E Lenkinski, Ivan Pedrosa, Ananth J Madhuranthakam
PURPOSE: To develop a whole-body MRI technique at 3T with improved lesion conspicuity for metastatic cancer detection using fast, high-resolution and high SNR T 2 -weighted (T 2 W) imaging with simultaneous fat and fluid suppression. THEORY AND METHODS: The proposed dual-echo T 2 -weighted acquisition for enhanced conspicuity of tumors (DETECT) acquires 4 images, in-phase (IP) and out-of-phase (OP) at a short and a long TE using single-shot turbo spin echo. The IP/OP images at the short and long TEs are reconstructed using the standard Dixon and shared-field-map Dixon reconstruction respectively, for robust fat-water separation...
February 14, 2018: Magnetic Resonance in Medicine: Official Journal of the Society of Magnetic Resonance in Medicine
https://www.readbyqxmd.com/read/29446125/feasibility-of-high-spatiotemporal-resolution-for-an-abbreviated-3d-radial-breast-mri-protocol
#5
Jorge E Jimenez, Roberta M Strigel, Kevin M Johnson, Leah C Henze Bancroft, Scott B Reeder, Walter F Block
PURPOSE: To develop a volumetric imaging technique with 0.8-mm isotropic resolution and 10-s/volume rate to detect and analyze breast lesions in a bilateral, dynamic, contrast-enhanced MRI exam. METHODS: A local low-rank temporal reconstruction approach that also uses parallel imaging and spatial compressed sensing was designed to create rapid volumetric frame rates during a contrast-enhanced breast exam (vastly undersampled isotropic projection [VIPR] spatial compressed sensing with temporal local low-rank [STELLR])...
February 14, 2018: Magnetic Resonance in Medicine: Official Journal of the Society of Magnetic Resonance in Medicine
https://www.readbyqxmd.com/read/29446118/water-suppression-in-the-human-brain-with-hypergeometric-rf-pulses-for-single-voxel-and-multi-voxel-mr-spectroscopy
#6
Kimberly L Chan, Ronald Ouwerkerk, Peter B Barker
PURPOSE: To develop and investigate a novel water suppression sequence with hypergeometric pulses at 3 T. METHODS: Simulations were used to optimize the delays and amplitudes of 5 hypergeometric prepulses, to minimize the residual water over a range of T 1 and B 1 values. Single-voxel data with hypergeometric water suppression (HGWS) prepulses were acquired in the centrum semiovale, 2 parietal regions, and insula of 7 subjects, and compared with VAPOR water suppression...
February 14, 2018: Magnetic Resonance in Medicine: Official Journal of the Society of Magnetic Resonance in Medicine
https://www.readbyqxmd.com/read/29436733/placental-perfusion-imaging-using-velocity-selective-arterial-spin-labeling
#7
Zungho Zun, Catherine Limperopoulos
PURPOSE: The placenta remains the least understood human organ, in large part because of the lack of noninvasive tools currently available to examine placental function in vivo. This study investigates the feasibility of using velocity-selective arterial spin labeling (VSASL) to assess placental perfusion. METHODS: In placental perfusion imaging, VSASL was compared with pseudocontinuous ASL (PCASL), which is currently the standard technique in brain arterial spin labeling (ASL)...
February 13, 2018: Magnetic Resonance in Medicine: Official Journal of the Society of Magnetic Resonance in Medicine
https://www.readbyqxmd.com/read/29427446/erratum-to-full-analytical-solution-of-the-bloch-equation-when-using-a-hyperbolic-secant-driving-function-magn-reson-med-2017-77-1630-1638
#8
Jinjin Zhang, Michael Garwood, Jang-Yeon Park
No abstract text is available yet for this article.
February 10, 2018: Magnetic Resonance in Medicine: Official Journal of the Society of Magnetic Resonance in Medicine
https://www.readbyqxmd.com/read/29427405/robust-sense-reconstruction-of-simultaneous-multislice-epi-with-low-rank-enhanced-coil-sensitivity-calibration-and-slice-dependent-2d-nyquist-ghost-correction
#9
Mengye Lyu, Markus Barth, Victor B Xie, Yilong Liu, Xin Ma, Yanqiu Feng, Ed X Wu
PURPOSE: To improve simultaneous multislice (SMS) EPI by robust Nyquist ghost correction in both coil sensitivity calibration and SMS reconstruction. METHODS: To derive coil sensitivity and slice-dependent phase difference map between positive- and negative-echo images, single-band EPI reference data are fully sampled with EPI parameters matched to SMS acquisition. First, the reference data are organized into positive- and negative-echo virtual channels where missing data are estimated using low-rank-based simultaneous autocalibrating and k-space estimation (SAKE) at small matrix size...
February 9, 2018: Magnetic Resonance in Medicine: Official Journal of the Society of Magnetic Resonance in Medicine
https://www.readbyqxmd.com/read/29427402/retrospective-multi-phase-non-contrast-enhanced-magnetic-resonance-angiography-romance-mra-for-robust-angiogram-separation-in-the-presence-of-cardiac-arrhythmia
#10
Hahnsung Kim, Suhyung Park, Eung Yeop Kim, Jaeseok Park
PURPOSE: To develop a novel, retrospective multi-phase non-contrast-enhanced MRA (ROMANCE MRA) in a single acquisition for robust angiogram separation even in the presence of cardiac arrhythmia. METHODS: In the proposed ROMANCE MRA, data were continuously acquired over all cardiac phases using retrospective, multi-phase flow-sensitive single-slab 3D fast spin echo (FSE) with variable refocusing flip angles, while an external pulse oximeter was in sync with pulse repetitions in FSE to record real-time information on cardiac cycles...
February 9, 2018: Magnetic Resonance in Medicine: Official Journal of the Society of Magnetic Resonance in Medicine
https://www.readbyqxmd.com/read/29427395/minimum-echo-time-press-based-proton-observed-carbon-edited-poce-mrs-in-rat-brain-using-simultaneous-editing-and-localization-pulses
#11
Chathura Kumaragamage, Dan Madularu, Axel P Mathieu, Derek Lupinsky, Robin A de Graaf, Jamie Near
PURPOSE: Indirect 13 C MRS by proton-observed carbon editing (POCE) is a powerful method to study brain metabolism. The sensitivity of POCE-MRS can be enhanced through the use of short TEs, which primarily minimizes homonuclear J-evolution related losses; previous POCE-MRS implementations use longer than optimal echo times due to sequence limitations, or short TE image selected in vivo spectroscopy-based multi-shot acquisitions for 3D localization. To that end, this paper presents a novel single-shot point resolved spectroscopy (PRESS)-localized POCE-MRS sequence that involves the application of simultaneous editing and localization pulses (SEAL)-PRESS, allowing the TE to be reduced to a theoretically optimal value of ∼ 1/JHC ...
February 9, 2018: Magnetic Resonance in Medicine: Official Journal of the Society of Magnetic Resonance in Medicine
https://www.readbyqxmd.com/read/29427393/dynamic-2d-self-phase-map-nyquist-ghost-correction-for-simultaneous-multi-slice-echo-planar-imaging
#12
Uten Yarach, Yi-Hang Tung, Kawin Setsompop, Myung-Ho In, Itthi Chatnuntawech, Renat Yakupov, Frank Godenschweger, Oliver Speck
PURPOSE: To develop a reconstruction pipeline that intrinsically accounts for both simultaneous multislice echo planar imaging (SMS-EPI) reconstruction and dynamic slice-specific Nyquist ghosting correction in time-series data. METHODS: After 1D slice-group average phase correction, the separate polarity (i.e., even and odd echoes) SMS-EPI data were unaliased by slice GeneRalized Autocalibrating Partial Parallel Acquisition. Both the slice-unaliased even and odd echoes were jointly reconstructed using a model-based framework, extended for SMS-EPI reconstruction that estimates a 2D self-phase map, corrects dynamic slice-specific phase errors, and combines data from all coils and echoes to obtain the final images...
February 9, 2018: Magnetic Resonance in Medicine: Official Journal of the Society of Magnetic Resonance in Medicine
https://www.readbyqxmd.com/read/29427389/in-vivo-self-gated-23-na-mri-at-7-t-using-an-oval-shaped-body-resonator
#13
Tanja Platt, Reiner Umathum, Thomas M Fiedler, Armin M Nagel, Andreas K Bitz, Florian Maier, Peter Bachert, Mark E Ladd, Mark O Wielpütz, Hans-Ulrich Kauczor, Nicolas G R Behl
PURPOSE: This work faces three challenges of sodium (23 Na) torso MRI on the way to quantitative 23 Na MRI: Development of a 23 Na radiofrequency transmit and receive coil covering a large part of the human body in width and length for 23 Na MRI at 7 T; reduction of blurring due to respiration in free-breathing 23 Na MRI using a self-gating approach; and reduction of image noise using a compressed-sensing reconstruction. METHODS: An oval-shaped birdcage resonator with a large field of view of (400 mm)3 and a homogeneous transmit and receive field distribution was designed, simulated, and implemented on a 7T MR system...
February 9, 2018: Magnetic Resonance in Medicine: Official Journal of the Society of Magnetic Resonance in Medicine
https://www.readbyqxmd.com/read/29427386/diffusion-mri-monitoring-of-specific-structures-in-the-irradiated-rat-brain
#14
Julie Constanzo, Matthieu Dumont, Réjean Lebel, Luc Tremblay, Kevin Whittingstall, Laurence Masson-Côté, Sameh Geha, Philippe Sarret, Martin Lepage, Benoit Paquette, Maxime Descoteaux
PURPOSE: The analysis of biological and mesoscopic structures properties by diffusion MRI (dMRI) in brain after radiation therapy remains challenging. In our study, we described the consequences associated with an unwanted dose to healthy tissue, assessing radiation-induced brain alterations of living rats with dMRI compared to histopathology and behavioral assays. METHODS: The right primary motor cortex M1 of the rat brain was targeted by stereotactic radiosurgery with a mean radiation dose of 41 Gy...
February 9, 2018: Magnetic Resonance in Medicine: Official Journal of the Society of Magnetic Resonance in Medicine
https://www.readbyqxmd.com/read/29427382/feasibility-of-in-vivo-measurement-of-glucose-metabolism-in-the-mouse-hypothalamus-by-1-h-13-c-mrs-at-14-1t
#15
Blanca Lizarbe, Hongxia Lei, Joao M N Duarte, Bernard Lanz, Antoine Cherix, Rolf Gruetter
PURPOSE: Determine the feasibility of 1 H-[13 C] MRS in the mouse hypothalamus using a 14.1T magnet. METHODS: We optimized the design of a 1 H-[13 C] surface coil to maximize the signal-to-noise ratio of 1 H-[13 C] MRS in the mouse hypothalamus. With enhanced signal, 13 C accumulation in glucose metabolites was measured in a 8.7 µL voxel in the hypothalamus of 5 healthy mice during the continuous administration of [1,6-13 C2 ]glucose. RESULTS: Accumulation of 13 C label in glucose C6 and lactate C3 was visible in the hypothalamus 11 min after glucose administration...
February 9, 2018: Magnetic Resonance in Medicine: Official Journal of the Society of Magnetic Resonance in Medicine
https://www.readbyqxmd.com/read/29427379/phase-correcting-non-local-means-filtering-for-diffusion-weighted-imaging-of-the-spinal-cord
#16
Sevgi Gokce Kafali, Tolga Çukur, Emine Ulku Saritas
PURPOSE: DWI suffers from low SNR when compared to anatomical MRI. To maintain reasonable SNR at relatively high spatial resolution, multiple acquisitions must be averaged. However, subject motion or involuntary physiological motion during diffusion-sensitizing gradients cause phase offsets among acquisitions. When the motion is localized to a small region, these phase offsets become particularly problematic. Complex averaging of acquisitions lead to cancellations from these phase offsets, whereas magnitude averaging results in noise amplification...
February 9, 2018: Magnetic Resonance in Medicine: Official Journal of the Society of Magnetic Resonance in Medicine
https://www.readbyqxmd.com/read/29427366/simultaneous-multislice-acquisition-without-trajectory-modification-for-hyperpolarized-13-c-experiments
#17
Angus Z Lau, Justin Y C Lau, Albert P Chen, Charles H Cunningham
PURPOSE: To investigate the feasibility of performing large FOV hyperpolarized 13 C metabolic imaging using simultaneous multislice excitation. METHODS: A spectral-spatial multislice excitation pulse was constructed by cosine modulation and incorporated into a 13 C spiral imaging sequence. Phantom and in vivo pig experiments were performed to test the feasibility of simultaneous multislice data acquisition and image reconstruction. In vivo cardiac-gated images of hyperpolarized pyruvate, bicarbonate, and lactate were obtained at 1 × 1 × 1 cm3 resolution over a 48 × 48 × 24 cm3 FOV with 2-fold acceleration in the slice direction...
February 9, 2018: Magnetic Resonance in Medicine: Official Journal of the Society of Magnetic Resonance in Medicine
https://www.readbyqxmd.com/read/29427349/quantifying-precision-in-cardiac-diffusion-tensor-imaging-with-second-order-motion-compensated-convex-optimized-diffusion-encoding
#18
Eric Aliotta, Kévin Moulin, Patrick Magrath, Daniel B Ennis
PURPOSE: To quantify the precision of in vivo cardiac DTI (cDTI) acquired with a spin echo, first- and second-order motion-compensated (M1 M2 ), convex optimized diffusion encoding (CODE) sequence. METHODS: Free-breathing CODE-M1 M2 cDTI were acquired in healthy volunteers (N = 10) at midsystole and diastole with 10 repeated acquisitions per phase. 95% confidence intervals of uncertainty in reconstructed diffusion tensor eigenvectors ( E→1, E→2, E→3), mean diffusivity (MD), fractional anisotropy (FA), and tensor Mode were measured using a bootstrapping approach...
February 9, 2018: Magnetic Resonance in Medicine: Official Journal of the Society of Magnetic Resonance in Medicine
https://www.readbyqxmd.com/read/29427325/controlling-t2-blurring-in-3d-rare-arterial-spin-labeling-acquisition-through-optimal-combination-of-variable-flip-angles-and-k-space-filtering
#19
Li Zhao, Ching-Di Chang, David C Alsop
PURPOSE: To improve the SNR efficiency and reduce the T2 blurring of 3D rapid acquisition with relaxation enhancement stack-of-spiral arterial spin labeling imaging by using variable refocusing flip angles and k-space filtering. METHODS: An algorithm for determining the optimal combination of variable flip angles and filtering correction is proposed. The flip angles are designed using extended phase graph physical simulations in an analytical and global optimization framework, with an optional constraint on deposited power...
February 9, 2018: Magnetic Resonance in Medicine: Official Journal of the Society of Magnetic Resonance in Medicine
https://www.readbyqxmd.com/read/29427315/an-8-15-channel-tx-rx-head-neck-rf-coil-combination-with-region-specific-b1-shimming-for-whole-brain-mri-focused-on-the-cerebellum-at-7t
#20
Viktor Pfaffenrot, Sascha Brunheim, Stefan H G Rietsch, Peter J Koopmans, Thomas M Ernst, Oliver Kraff, Stephan Orzada, Harald H Quick
PURPOSE: To design and evaluate an 8/15-channel transmit/receive (Tx/Rx) head-neck RF coil combination with region-specific B1+ shimming for whole-brain MRI with focus on improved functional MRI of the cerebellum at 7 T. METHODS: An 8-channel transceiver RF head coil was combined with a 7-channel receive-only array. The noise parameters and acceleration capabilities of this 8Tx/15Rx coil setup were compared with a commercially available 1Tx/32Rx RF head coil. Region-specific 8-channel B1+ shimming was applied when using the 8Tx/15Rx RF coil...
February 9, 2018: Magnetic Resonance in Medicine: Official Journal of the Society of Magnetic Resonance in Medicine
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