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Liver Transplantation

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https://www.readbyqxmd.com/read/29149510/transferrin-as-a-predictor-of-survival-in-cirrhosis
#1
André Viveiros, Armin Finkenstedt, Benedikt Schaefer, Mattias Mandorfer, Bernhard Scheiner, Konrad Lehner, Moritz Tobiasch, Thomas Reiberger, Herbert Tilg, Michael Edlinger, Heinz Zoller
BACKGROUND AND AIMS: Patients with cirrhosis frequently present with high serum ferritin and low transferrin concentrations, reflecting impaired liver function and inflammation. Recent studies have shown that transferrin and its saturation with iron are MELD-independent predictors of mortality in patients with acute on chronic liver failure or decompensated cirrhosis. The aim of this study was to evaluate the prognostic utility of serum iron parameters in relation to markers of liver function and immune activation...
November 17, 2017: Liver Transplantation
https://www.readbyqxmd.com/read/29149464/novel-intra-operative-management-in-the-meld-na-era-continuous-veno-venous-hemofiltration-for-severe-hyponatremia-in-liver-transplantation
#2
Shunji Nagai, Dilip Moonka, Anita Patel
No abstract text is available yet for this article.
November 17, 2017: Liver Transplantation
https://www.readbyqxmd.com/read/29144592/ex-vivo-reduction-of-thickness-in-the-left-lateral-section-to-tailor-the-graft-size-in-infantile-split-deceased-donor-liver-transplantation
#3
Seisuke Sakamoto, Kengo Sasaki, Hajime Uchida, Toshihiro Kitajima, Soichi Narumoto, Yoshihiro Hirata, Tomoro Hishiki, Akinari Fukuda, Mureo Kasahara
No abstract text is available yet for this article.
November 16, 2017: Liver Transplantation
https://www.readbyqxmd.com/read/29144580/higher-retransplantation-rate-following-extended-right-split-liver-transplantation-an-analysis-from-the-eurotransplant-liver-follow-up-registry
#4
J Andrassy, S Wolf, M Lauseker, M Angele, M D van Rosmalen, U Samuel, X Rogiers, J Werner, M Guba
Split liver transplantation (SLT) has been perceived as an important strategy to increase the supply of liver grafts by creating 2 transplants from 1 allograft. The Eurotransplant allocation system (ELAS) envisages that the ERLs after splitting (usually in the pediatric center) are almost exclusively shipped to a second center. Whether the ELAS policy impacts the graft and patient survival of ERLT in comparison to WLT recipients remains unclear. Data on all LTs performed between 2007 and 2013 were retrieved from the ET Liver follow-up Registry (n=5351)...
November 16, 2017: Liver Transplantation
https://www.readbyqxmd.com/read/29140601/pilot-study-of-living-donor-liver-transplantation-for-patients-with-hcc-exceeding-milan-criteria-bclc-extended-criteria
#5
Josep M Llovet, Mihai Pavel, Jordi Rimola, Maria Alba Diaz, Jordi Colmenero, David Saavedra, Constantino Fondevila, Carmen Ayuso, Josep Fuster, Pere Ginès, Jordi Bruix, Juan Carlos Garcia Valdecasas
BACKGROUND & AIMS: A subset of patients with hepatocellular carcinoma (HCC) beyond Milan criteria might obtain acceptable survival outcomes after liver transplantation. Living donor liver transplantation (LDLT) has emerged as a feasible alternative to overcome the paucity of donors. METHODS: In 2001 we started a protocol for LDLT in Child A-B patients with HCC fulfilling a set of criteria - the BCLC expanded criteria- that expanded the conventional indications of transplantation: 1 tumor ≤ 7cm, 5 tumors ≤ 3cm, 3 tumors ≤ 5cm without macrovascular invasion or down-staging to Milan after loco-regional therapies...
November 15, 2017: Liver Transplantation
https://www.readbyqxmd.com/read/29140579/utilisation-of-dcd-liver-grafts-balancing-the-risk-between-donor-and-recipient
#6
LETTER
Marit Kalisvaart, Andrea Schlegel, Paolo Muiesan
No abstract text is available yet for this article.
November 15, 2017: Liver Transplantation
https://www.readbyqxmd.com/read/29125712/lipid-metabolism-and-functional-assessment-of-discarded-human-livers-with-steatosis-undergoing-24-hours-normothermic-machine-perfusion
#7
Qiang Liu, Ahmed Nassar, Laura Buccini, Giuseppe Iuppa, Basem Soliman, Daniele Pezzati, Ahmed Hassan, Matthew Blum, William Baldwin, Ana Bennett, Kenneth Chavin, Toshihiro Okamoto, Teresa Diago Uso, John Fung, Kareem Abu-Elmagd, Charles Miller, Cristiano Quintini
Normothermic machine perfusion (NMP) is an emerging technology to preserve liver allografts more effectively than cold storage (CS). However, little is known about the effect of NMP on steatosis, and the markers indicative of hepatic quality during NMP. To address these points we perfused 10 discarded human livers with oxygenated NMP for 24 hours after 4-6 hours of CS. All livers had variable degree of steatosisat at baseline. The perfusate consisted of packed red blood cells and fresh frozen plasma. Perfusate analysis showed an increase in triglyceride levels from the 1st hour (median 127 mg/dL; interquartile range 95-149) to 24th hour of perfusion (203;171-304) (p=0...
November 10, 2017: Liver Transplantation
https://www.readbyqxmd.com/read/29125693/current-status-of-liver-transplantation-for-cholangiocarcinoma
#8
LETTER
Seogsong Jeong, Meng Sha, Qiang Xia
No abstract text is available yet for this article.
November 10, 2017: Liver Transplantation
https://www.readbyqxmd.com/read/29125687/liver-transplantation-for-expanded-criteria-malignant-diseases-contra
#9
REVIEW
Benedikt Schaefer, Heinz Zoller, Stefan Schneeberger
No abstract text is available yet for this article.
November 10, 2017: Liver Transplantation
https://www.readbyqxmd.com/read/29125676/decreasing-mortality-and-disease-severity-in-hepatitis-c-patients-awaiting-liver-transplantation-in-the-united-states
#10
Allison Kwong, W Ray Kim, Ajitha Mannalithara, Nae-Yun Heo, Prowpanga Udompap, Donghee Kim
BACKGROUND: Hepatitis C virus (HCV) infection has been the leading indication for liver transplantation (LT) in the United States. Since 2013, interferon-free antiviral therapy has led to sustained virologic response in many LT candidates. We compared the waitlist mortality of HCV patients with that of patients with other chronic liver diseases. METHODS: Data for primary LT candidates were obtained from the Organ Procurement and Transplantation Network database...
November 10, 2017: Liver Transplantation
https://www.readbyqxmd.com/read/29125672/reply-to-17-638
#11
LETTER
Nicolas Goldaracena, Andre Gorgen, Gonzalo Sapisochin
No abstract text is available yet for this article.
November 10, 2017: Liver Transplantation
https://www.readbyqxmd.com/read/29108119/duct-to-duct-biliary-reconstruction-in-pediatric-split-liver-transplantation
#12
Cahit Yilmaz, Can A Karaca, Rasim Ferecov, Zaza Iakobadze, Kamil Kilic, Adnan Tosun, Murat Kilic
No abstract text is available yet for this article.
November 6, 2017: Liver Transplantation
https://www.readbyqxmd.com/read/29087030/more-is-less-calling-for-joining-forces-for-rare-pediatric-liver-tumors-research
#13
EDITORIAL
Jean de Ville de Goyet, Bruce Morland, Piotr Czauderna
No abstract text is available yet for this article.
October 31, 2017: Liver Transplantation
https://www.readbyqxmd.com/read/29087021/still-ironing-out-the-best-way-to-diagnose-infection
#14
EDITORIAL
Peter V Chin-Hong
No abstract text is available yet for this article.
October 31, 2017: Liver Transplantation
https://www.readbyqxmd.com/read/29080242/can-negligible-hepatic-steatosis-determined-by-mri-proton-density-fat-fraction-obviate-the-need-for-liver-biopsy-in-potential-liver-donors
#15
Janakan Satkunasingham, Hooman Hosseini Nik, Sandra Fischer, Ravi Menezes, Nazia Selzner, Mark Cattral, David Grant, Kartik Jhaveri
PURPOSE: To determine whether magnetic resonance proton density fat fraction (MR-PDFF) estimate of negligible hepatic fat percentage (<5%) can exclude significant hepatic steatosis (≥ 10%) in living liver donor candidates obviating the need for liver biopsy. To perform intra-individual comparisons between MR-PDFF techniques for hepatic steatosis quantification. MATERIALS AND METHODS: In an ethics approved retrospective study, 144 liver donor candidates with MR spectroscopy (MRS) and six-echo Dixon MRI between 2013 and 2015 were included...
October 28, 2017: Liver Transplantation
https://www.readbyqxmd.com/read/29080241/next-generation-sequencing-in-pediatric-hepatology-and-liver-transplantation
#16
REVIEW
Emanuele Nicastro, Lorenzo D'Antiga
Next Generation Sequencing (NGS) has revolutionized the analysis of human genetic variations, offering a highly cost-effective way to diagnose monogenic diseases (MDs). Since nearly half of children with chronic liver disorders have a genetic cause and approximately 20% of pediatric liver transplants are performed in children with MDs, NGS offers the opportunity to significantly improve the diagnostic yield in this field. Among the NGS strategies, the use of targeted gene panels has proven useful to rapidly and reliably confirm a clinical suspicion, whereas the whole exome sequencing (WES) with variants filtering has been adopted to assist the diagnostic work up in unclear clinical scenarios...
October 28, 2017: Liver Transplantation
https://www.readbyqxmd.com/read/29080238/-the-role-of-molecular-adsorbent-recirculating-system-in-pediatric-acute-liver-failure
#17
Jesús Quintero Bernabeu, Juan Ortega López, Javier Juampérez Goñi, Ecaterina Julio Tatis, Maria Mercadal, Itxarone Bilbao Aguirre, Carlos Rodrigo Gonzalo de Liria, Ramon Charco Torra
No abstract text is available yet for this article.
October 28, 2017: Liver Transplantation
https://www.readbyqxmd.com/read/29077253/extended-oncologic-indications-in-liver-transplantation-pro-with-caution
#18
REVIEW
Vincenzo Mazzaferro, Carlo Battiston, Carlo Sposito
No abstract text is available yet for this article.
October 27, 2017: Liver Transplantation
https://www.readbyqxmd.com/read/29069533/treatment-of-hepatitis-c-with-direct-acting-antivirals-in-patients-with-hepatocellular-carcinoma-before-liver-transplantation-still-an-open-issue
#19
LETTER
Federico Piñero, Marcelo Silva
No abstract text is available yet for this article.
October 25, 2017: Liver Transplantation
https://www.readbyqxmd.com/read/29024347/long-term-outcome-of-rendezvous-technique-for-hepaticojejunal-anastomotic-obstruction-after-pediatric-living-donor-liver-transplantation
#20
Yukihiro Sanada, Tomonori Yano, Taizen Urahashi, Yoshiyuki Ihara, Noriki Okada, Naoya Yamada, Yuta Hirata, Takumi Katano, Hironori Yamamoto, Koichi Mizuta
No abstract text is available yet for this article.
October 12, 2017: Liver Transplantation
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