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Xiangdong Wang, Xinjun Chen, Ming Zheng, Chengyao Liu, Chengshuo Wang, Luo Zhang
OBJECTIVES/HYPOTHESIS: To examine the anatomic relationships between the lower end opening into the inferior meatus of the bony nasolacrimal duct (NLD) and the anterior wall of the maxillary sinus. STUDY DESIGN: Anatomical investigation. METHODS: A total of 206 individuals were recruited for detailed anatomic investigation of the lower end of the bony NLD and their relation to the anterior wall of the maxillary sinus by high-resolution computed tomography (HRCT) imaging...
August 10, 2018: Laryngoscope
Matias Gomez Galarce, Juan C Yanez-Siller, Ricardo L Carrau, Alaa Montaser, Lucas Ramos Lima, Diego Servian, Bradley A Otto, Daniel M Prevedello, Cristian A Naudy
OBJECTIVES/HYPOTHESIS: Define the anatomic distribution of the olfactory filaments within specific mucosal regions of the nasal cavity. STUDY DESIGN: Cadaveric study. METHODS: Seventeen cadaveric specimens (34 sides) were dissected to study the anatomical distribution and density of olfactory fila within different regions of the nasal cavity. Olfactory fila were dissected retrogradely to their point of entry into the anterior cranial fossa through the cribriform plate...
August 10, 2018: Laryngoscope
Suresh Mohan, Iván Coto Hernández, Wenjin Wang, Kaiyang Yin, Cathryn A Sundback, Ulrike G K Wegst, Nate Jowett
OBJECTIVE: Use of cell culture and conventional in vivo mammalian models to assess nerve regeneration across guidance conduits is resource-intensive. Herein we describe a high-throughput platform utilizing transgenic mice for stain-free axon visualization paired with rapid cryosection techniques for low-cost screening of novel bioengineered nerve guidance conduit performance. METHODS: Interposition repair of sciatic nerve transection in mice expressing yellow fluorescent protein in peripheral neurons (Thy1...
August 10, 2018: Laryngoscope
Dante De Paz, Kai-Ping Chang, Huang-Kai Kao, William Wei-Kai Lao, Yu-Chen Huang, Yu-Liang Chang, Yenlin Huang
OBJECTIVES/HYPOTHESIS: The role of tumor-associated tissue eosinophilia (TATE) in oral cavity cancer remains quite controversial. This study investigated the potential role of TATE in tongue squamous cell carcinoma (TSCC). STUDY DESIGN: Retrospective case series. METHODS: This study retrospectively enrolled 259 consecutive TSCC patients who underwent surgery between July 2004 and December 2015. Histopathological examinations for TATE in TSCC tumors were reviewed, and the association of TATE with different clinicopathological factors was evaluated...
August 10, 2018: Laryngoscope
Sophie G Shay, Jonathan D Chrin, Marilene B Wang, Abie H Mendelsohn
OBJECTIVES/HYPOTHESIS: To objectively assess the initial and long-term retention of robotic surgical skills of otolaryngology residents. STUDY DESIGN: This study was performed in an academic otolaryngology residency training program. Between October 2015 and November 2016, residents were invited to complete a prospective, multiphase robotic surgical skills training course: 1) online da Vinci Surgical System Assessment and didactic, 2) faculty-supervised robotic simulator training, 3) robotic docking and draping training, 4) robotic dry-lab exercises...
August 10, 2018: Laryngoscope
Eric H Zhao, Kalin Nishimori, Jacob Brady, Sana H Siddiqui, Jean Anderson Eloy, Soly Baredes, Richard Chan W Park
OBJECTIVES/HYPOTHESIS: Evaluate risk factors for unplanned reoperation following free flap surgery of the head and neck. STUDY DESIGN: Retrospective database review. METHODS: The National Surgical Quality Improvement Program database was queried for free flap surgeries of the head and neck between 2010 and 2014. Bivariate and multivariate analyses were performed to compare perioperative variables and postoperative complications in patients with and without unplanned reoperation...
August 10, 2018: Laryngoscope
Chet C Xu, Ang Gao, Song Zhang
OBJECTIVES: The primary objective was to investigate the left-right vocal fold symmetry in rheological and histological properties using a rabbit model. The other objective was to develop statistical models for the comparison of rheological properties between paired vocal folds. METHODS: Viscoelastic shear properties of six pairs of vocal fold lamina propria specimens were measured over a frequency range of 1 to 250 Hz by a linear, controlled-strain, simple-shear rheometer...
August 10, 2018: Laryngoscope
Craig Zalvan, Craig Berzofsky, Raj Tiwari, Jan Geliebter
OBJECTIVE/HYPOTHESIS: Neurogenic chronic cough typically presents as a postviral chronic cough, often with paroxysms of coughing preceded by a tickle sensation with multiple triggers and often recalcitrant to multiple treatments for reflux disease, sinus disease, and asthma. Current treatment uses neuromodulating agents with moderate success. Post nasal drainage and laryngopharyngeal reflux can be triggers in the setting of laryngopharyngeal hypersensitivity. Treatment will focus on trigger reduction using nasal toilet and a dietary regimen for laryngopharyngeal reflux...
August 10, 2018: Laryngoscope
Colin Huntley, Armin Steffen, Karl Doghramji, Benedikt Hofauer, Clemens Heiser, Maurits Boon
OBJECTIVES/HYPOTHESIS: An elevated body mass index (BMI) influences the severity of disease and treatment options utilized for obstructive sleep apnea (OSA). With this study, we aim to evaluate a cohort of patients undergoing upper airway stimulation (UAS) for treatment of OSA and assess the impact of BMI on surgical and quality of life outcomes. METHODS: We designed a case-control, retrospective review, of all patients undergoing UAS at two academic institutions between 2014 and 2017...
August 10, 2018: Laryngoscope
Daniel Neu, Grégory Nawara, Johan Newell, David Bouchez, Olivier Mairesse
We report the case of obstructive sleep apnea in a 19-year-old, otherwise healthy male presenting with persistent daytime sleepiness and nonrestorative sleep after velo- and uvuloplasty. An individually tailored prototype of an orally inserted pharyngeal stenting device was proposed in the framework of a first clinical feasibility trial. The noninvasive, easily self-administered device is mounted on a simple inferior dental guard. Baseline total apnea-hypopnea index (AHI) was 15.5 and 24.4 per hour of rapid eye movement (REM) sleep...
August 10, 2018: Laryngoscope
Ahmad F Mahmoud, Erica R Thaler
No abstract text is available yet for this article.
August 10, 2018: Laryngoscope
Makoto Hosoya, Rika Kobayashi, Toyota Ishii, Masamitsu Senarita, Hiroyuki Kuroda, Hayato Misawa, Fujinobu Tanaka, Tetsuya Takiguchi, Masatsugu Tashiro, Sawako Masuda, Sho Hashimoto, Fumiyuki Goto, Shujiro Minami, Nobuko Yamamoto, Ryoto Nagai, Akiko Sayama, Takeshi Wakabayashi, Keitaro Toshikuni, Rumi Ueha, Yoko Fujimaki, Mihiro Takazawa, Sotaro Sekimoto, Kenji Itoh, Takaharu Nito, Akiko Kada, Koichi Tsunoda
OBJECTIVES/HYPOTHESIS: Vocal fold polyps and nodules are common benign laryngeal lesions. Currently, the Japanese health insurance system covers surgical interventions. However, the establishment of more cost-effective conservative methods is required, because healthcare costs are viewed as a major concern, and the government and taxpayers are demanding more economical, effective treatments. In this situation, more suitable vocal hygiene education may be important for the success of cost-effective conservative treatment...
August 6, 2018: Laryngoscope
Meghan M Crippen, Marcus L Elias, Joseph S Weisberger, Jacob S Brady, Jean Anderson Eloy, Soly Baredes, Richard Chan Woo Park
OBJECTIVES/HYPOTHESIS: To investigate the risk factors for refusal of recommended surgery in head and neck squamous cell carcinoma (HNSCC) treatment STUDY DESIGN: Retrospective review of a national database. METHODS: The Surveillance, Epidemiology, and End Results database was queried for all cases of HNSCC from 1989 to 2014. Patients who underwent recommended surgery (N = 98,270) were identified and compared to patients who refused recommended surgery (N = 3,582)...
August 2, 2018: Laryngoscope
Alice L Tang, Allen M Seiden
No abstract text is available yet for this article.
July 30, 2018: Laryngoscope
Alexandra E Quimby, Diana Khalil, Stephanie Johnson-Obaseki
OBJECTIVE: Controversy exists regarding the surgical management of cutaneous melanoma and the optimal timing of reconstruction. One approach to ensuring an oncologically sound outcome is a two-stage procedure, with reconstruction delayed for negative permanent section margins. Alternatively, a single-stage excision with immediate reconstruction is advantageous because it limits both resource use and patient morbidity from multiple procedures. We sought to examine available published data on the oncologic outcomes associated with immediate versus delayed reconstruction of cutaneous melanoma in the head and neck region...
June 22, 2018: Laryngoscope
Rachel R Anfang, Kris R Jatana, Rebecca L Linn, Keith Rhoades, Jared Fry, Ian N Jacobs
OBJECTIVES/HYPOTHESIS: Ingestion of button batteries (BB) can rapidly lead to caustic esophageal injury in infants and children, resulting in significant morbidity and mortality. To identify novel mitigation strategies, we tested common weakly acidic household beverages, viscous liquids, and Carafate® for their ability to act as protective esophageal irrigations until endoscopic removal of the BB. STUDY DESIGN: Cadaveric and live animal model. METHODS: Apple juice, orange juice, Gatorade®, POWERADE®, pure honey, pure maple syrup, and Carafate® were screened using a 3 V lithium (3 V-CR2032) BB on cadaveric porcine esophagus...
June 11, 2018: Laryngoscope
Michael Griessl, Anna-Maria Buchberger, Sybille Regn, Kilian Kreutzer, Katharina Storck
OBJECTIVES/HYPOTHESIS: To find an alternative approach to contemporary techniques in tissue augmentation and reconstruction, tissue engineering strategies aim to involve adipose-derived stem and stromal cells (ASCs) harboring a strong differentiation potential into various tissue types such as bone, cartilage, and fat. STUDY DESIGN: Animal research. METHODS: The stromal vascular fraction (SVF) was used directly as a cell source to provide a potential alternative to contemporary ASC-based adipose tissue engineering...
June 2018: Laryngoscope
Ya Hui Tang, R Will Thompson, Cherie-Ann Nathan, Jonathan Steven Alexander, Timothy Lian
OBJECTIVES: The lack of real-time assessment of vascular perfusion changes remains a major weakness in assessing the efficacy of bone marrow stromal cells (BMSC) therapeutic ischemia reperfusion (I/R) injury. This study provides for the first time the real-time in vivo perfusion monitoring in I/R mice with BMSC therapy. STUDY DESIGN: Animal model. METHODS: Surgically created cutaneous flaps perfused by the inferior epigastric vessels were subjected to 3...
June 2018: Laryngoscope
Ashley C Mays, Diana Bell, Renata Ferrarotto, Jack Phan, Dianna Roberts, Clifton D Fuller, Steven J Frank, Shaan M Raza, Michael E Kupferman, Franco DeMonte, Ehab Y Hanna, Shirley Y Su
OBJECTIVE: Compare outcomes of patients with olfactory neuroblastoma (ONB) without skull base involvement treated with and without resection of the dura and olfactory bulb. METHODS: Retrospective review of ONB patients treated from 1992 to 2013 at the MD Anderson Cancer Center (The University of Texas, Houston, Texas, U.S.A.). Primary outcomes were overall and disease-free survival. RESULTS: Thirty-five patients were identified. Most patients had Kadish A/B...
June 2018: Laryngoscope
VyVy N Young, Kwonho Jeong, Scott D Rothenberger, Amanda I Gillespie, Libby J Smith, Jackie L Gartner-Schmidt, Clark A Rosen
OBJECTIVES/HYPOTHESIS: The Voice Handicap Index-10 (VHI-10) is commonly used to measure patients' perception of vocal handicap. Clinical consensus has previously defined clinically meaningful improvement as a decrease ≥5. This study determines the minimal clinically important difference (MCID) for VHI-10 in patients with unilateral vocal fold paralysis (UVFP) using anchor-based methodology. STUDY DESIGN: Prospective cohort questionnaire analysis. METHODS: Two hundred eighty-one UVFP patients completed the VHI-10 on two consecutive visits (within 3 months)...
June 2018: Laryngoscope
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