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Lancet Neurology

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https://www.readbyqxmd.com/read/30415935/the-rise-of-neurology-in-haiti
#1
Jacquelyn Corley
No abstract text is available yet for this article.
November 8, 2018: Lancet Neurology
https://www.readbyqxmd.com/read/30415934/timing-of-anticoagulation-after-recent-ischaemic-stroke-in-patients-with-atrial-fibrillation
#2
REVIEW
David J Seiffge, David J Werring, Maurizio Paciaroni, Jesse Dawson, Steven Warach, Truman J Milling, Stefan T Engelter, Urs Fischer, Bo Norrving
BACKGROUND: About 13-26% of all acute ischaemic strokes are related to non-valvular atrial fibrillation, the most common cardiac arrhythmia globally. Deciding when to initiate oral anticoagulation in patients with non-valvular atrial fibrillation is a longstanding, common, and unresolved clinical challenge. Although the risk of early recurrent ischaemic stroke is high in this population, early oral anticoagulation is suspected to increase the risk of potentially harmful intracranial haemorrhage, including haemorrhagic transformation of the infarct...
November 8, 2018: Lancet Neurology
https://www.readbyqxmd.com/read/30413385/penumbral-imaging-and-functional-outcome-in-patients-with-anterior-circulation-ischaemic-stroke-treated-with-endovascular-thrombectomy-versus-medical-therapy-a-meta-analysis-of-individual-patient-level-data
#3
Bruce C V Campbell, Charles B L M Majoie, Gregory W Albers, Bijoy K Menon, Nawaf Yassi, Gagan Sharma, Wim H van Zwam, Robert J van Oostenbrugge, Andrew M Demchuk, Francis Guillemin, Philip White, Antoni Dávalos, Aad van der Lugt, Kenneth S Butcher, Aboubaker Cherifi, Henk A Marquering, Geoffrey Cloud, Juan M Macho Fernández, Jeremy Madigan, Catherine Oppenheim, Geoffrey A Donnan, Yvo B W E M Roos, Jai Shankar, Hester Lingsma, Alain Bonafé, Hélène Raoult, María Hernández-Pérez, Aditya Bharatha, Reza Jahan, Olav Jansen, Sébastien Richard, Elad I Levy, Olvert A Berkhemer, Marc Soudant, Lucia Aja, Stephen M Davis, Timo Krings, Marie Tisserand, Luis San Román, Alejandro Tomasello, Debbie Beumer, Scott Brown, David S Liebeskind, Serge Bracard, Keith W Muir, Diederik W J Dippel, Mayank Goyal, Jeffrey L Saver, Tudor G Jovin, Michael D Hill, Peter J Mitchell
BACKGROUND: CT perfusion (CTP) and diffusion or perfusion MRI might assist patient selection for endovascular thrombectomy. We aimed to establish whether imaging assessments of irreversibly injured ischaemic core and potentially salvageable penumbra volumes were associated with functional outcome and whether they interacted with the treatment effect of endovascular thrombectomy on functional outcome. METHODS: In this systematic review and meta-analysis, the HERMES collaboration pooled patient-level data from all randomised controlled trials that compared endovascular thrombectomy (predominantly using stent retrievers) with standard medical therapy in patients with anterior circulation ischaemic stroke, published in PubMed from Jan 1, 2010, to May 31, 2017...
November 6, 2018: Lancet Neurology
https://www.readbyqxmd.com/read/30413384/patients-with-large-brain-infarcts-might-also-benefit-from-thrombectomy
#4
Steven Warach
No abstract text is available yet for this article.
November 6, 2018: Lancet Neurology
https://www.readbyqxmd.com/read/30409709/global-regional-and-national-burden-of-motor-neuron-diseases-1990-2016-a-systematic-analysis-for-the-global-burden-of-disease-study-2016
#5
(no author information available yet)
BACKGROUND: Understanding how prevalence, incidence, and mortality of motor neuron diseases change over time and by location is crucial for understanding the causes of these disorders and for health-care planning. Our aim was to produce estimates of incidence, prevalence, and disability-adjusted life-years (DALYs) for motor neuron diseases for 195 countries and territories from 1990 to 2016 as part of the Global Burden of Diseases, Injuries, and Risk Factors Study (GBD) 2016. METHODS: The motor neuron diseases included in this study were amyotrophic lateral sclerosis, spinal muscular atrophy, hereditary spastic paraplegia, primary lateral sclerosis, progressive muscular atrophy, and pseudobulbar palsy...
November 2, 2018: Lancet Neurology
https://www.readbyqxmd.com/read/30409708/global-burden-of-motor-neuron-diseases-mind-the-gaps
#6
Orla Hardiman
No abstract text is available yet for this article.
November 2, 2018: Lancet Neurology
https://www.readbyqxmd.com/read/30366869/correction-to-lancet-neurol-2018-published-online-sept-28-http-doi-org-10-1016-s1474-4422-18-30319-3
#7
(no author information available yet)
No abstract text is available yet for this article.
October 23, 2018: Lancet Neurology
https://www.readbyqxmd.com/read/30366868/circadian-rhythm-and-epilepsy
#8
REVIEW
Sofia Khan, Lino Nobili, Ramin Khatami, Tobias Loddenkemper, Christian Cajochen, Prof Derk-Jan Dijk, Sofia H Eriksson
Advances in diagnostic technology, including chronic intracranial EEG recordings, have confirmed the clinical observation of different temporal patterns of epileptic activity and seizure occurrence over a 24-h period. The rhythmic patterns in epileptic activity and seizure occurrence are probably related to vigilance states and circadian variation in excitatory and inhibitory balance. Core circadian genes BMAL1 and CLOCK, which code for transcription factors, have been shown to influence excitability and seizure threshold...
October 23, 2018: Lancet Neurology
https://www.readbyqxmd.com/read/30366867/bart-de-strooper-views-from-the-rooftop
#9
Adrian Burton
No abstract text is available yet for this article.
October 23, 2018: Lancet Neurology
https://www.readbyqxmd.com/read/30361164/stephen-waxman-pioneer-in-axons-their-disorders-and-pain
#10
Tony Kirby
No abstract text is available yet for this article.
October 22, 2018: Lancet Neurology
https://www.readbyqxmd.com/read/30340930/optimal-stroke-prevention-in-patients-with-patent-foramen-ovale
#11
Bernhard Meier
No abstract text is available yet for this article.
October 16, 2018: Lancet Neurology
https://www.readbyqxmd.com/read/30337274/igf-1-for-spinal-and-bulbar-muscular-atrophy-hope-and-challenges
#12
Atsushi Hashizume, Masahisa Katsuno
No abstract text is available yet for this article.
October 15, 2018: Lancet Neurology
https://www.readbyqxmd.com/read/30337273/safety-tolerability-and-preliminary-efficacy-of-an-igf-1-mimetic-in-patients-with-spinal-and-bulbar-muscular-atrophy-a-randomised-placebo-controlled-trial
#13
Christopher Grunseich, Ram Miller, Therese Swan, David J Glass, Mohamed El Mouelhi, Mara Fornaro, Olivier Petricoul, Igor Vostiar, Ronenn Roubenoff, Matthew N Meriggioli, Angela Kokkinis, Robert D Guber, Maher S Budron, John Vissing, Gianni Soraru, Tahseen Mozaffar, Albert Ludolph, John T Kissel, Kenneth H Fischbeck
BACKGROUND: Spinal and bulbar muscular atrophy is an X-linked neuromuscular disease caused by CAG repeat expansion in the androgen receptor gene. Patients with this disease have low concentrations of insulin-like growth factor-1 (IGF-1), and studies of overexpression and administration of IGF-1 showed benefit in a transgenic model; thus the IGF-1 pathway presents as a potential treatment target. We assessed safety, tolerability, and preliminary efficacy of BVS857, an IGF-1 mimetic, in patients with spinal and bulbar muscular atrophy...
October 15, 2018: Lancet Neurology
https://www.readbyqxmd.com/read/30337272/argentina-s-unanswered-stroke-health-care-question
#14
Adrian Burton
No abstract text is available yet for this article.
October 15, 2018: Lancet Neurology
https://www.readbyqxmd.com/read/30274772/rivaroxaban-or-aspirin-for-patent-foramen-ovale-and-embolic-stroke-of-undetermined-source-a-prespecified-subgroup-analysis-from-the-navigate-esus-trial
#15
Scott E Kasner, Balakumar Swaminathan, Pablo Lavados, Mukul Sharma, Keith Muir, Roland Veltkamp, Sebastian F Ameriso, Matthias Endres, Helmi Lutsep, Steven R Messé, J David Spence, Krassen Nedeltechev, Kanjana Perera, Gustavo Santo, Veronica Olavarria, Arne Lindgren, Shrikant Bangdiwala, Ashkan Shoamanesh, Scott D Berkowitz, Hardi Mundl, Stuart J Connolly, Robert G Hart
BACKGROUND: Patent foramen ovale (PFO) is a contributor to embolic stroke of undetermined source (ESUS). Subgroup analyses from previous studies suggest that anticoagulation could reduce recurrent stroke compared with antiplatelet therapy. We hypothesised that anticoagulant treatment with rivaroxaban, an oral factor Xa inhibitor, would reduce the risk of recurrent ischaemic stroke compared with aspirin among patients with PFO enrolled in the NAVIGATE ESUS trial. METHODS: NAVIGATE ESUS was a double-blinded, randomised, phase 3 trial done at 459 centres in 31 countries that assessed the efficacy and safety of rivaroxaban versus aspirin for secondary stroke prevention in patients with ESUS...
September 28, 2018: Lancet Neurology
https://www.readbyqxmd.com/read/30170897/pharyngeal-stimulation-after-stroke-more-evidence-is-needed
#16
Martin Dennis
No abstract text is available yet for this article.
August 28, 2018: Lancet Neurology
https://www.readbyqxmd.com/read/30126645/risk-predictors-to-limit-neuronal-loss-after-intracerebral-haemorrhage
#17
M Edip Gurol
No abstract text is available yet for this article.
August 17, 2018: Lancet Neurology
https://www.readbyqxmd.com/read/30353868/global-regional-and-national-burden-of-migraine-and-tension-type-headache-1990-2016-a-systematic-analysis-for-the-global-burden-of-disease-study-2016
#18
(no author information available yet)
BACKGROUND: Through the Global Burden of Diseases, Injuries, and Risk Factors (GBD) studies, headache has emerged as a major global public health concern. We aimed to use data from the GBD 2016 study to provide new estimates for prevalence and years of life lived with disability (YLDs) for migraine and tension-type headache and to present the methods and results in an accessible way for clinicians and researchers of headache disorders. METHODS: Data were derived from population-based cross-sectional surveys on migraine and tension-type headache...
November 2018: Lancet Neurology
https://www.readbyqxmd.com/read/30353867/soundscapes-of-the-mind
#19
Emilia Harding
No abstract text is available yet for this article.
November 2018: Lancet Neurology
https://www.readbyqxmd.com/read/30353866/ophir-keret
#20
(no author information available yet)
No abstract text is available yet for this article.
November 2018: Lancet Neurology
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