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Lancet Neurology

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https://www.readbyqxmd.com/read/28434855/health-care-use-before-a-first-demyelinating-event-suggestive-of-a-multiple-sclerosis-prodrome-a-matched-cohort-study
#1
José M A Wijnands, Elaine Kingwell, Feng Zhu, Yinshan Zhao, Tanja Högg, Karen Stadnyk, Okechukwu Ekuma, Xinya Lu, Charity Evans, John D Fisk, Ruth Ann Marrie, Helen Tremlett
BACKGROUND: Degenerative processes in neurodegenerative diseases can start years before clinical manifestation. We aimed to establish whether a multiple sclerosis prodromal period exists by examining patterns of health-care use before a first demyelinating event. METHODS: In this matched cohort study, we used data from linked health administrative and clinical databases from four Canadian provinces (British Columbia, Saskatchewan, Manitoba, and Nova Scotia) to compare hospital, physician, and prescription use data from people with multiple sclerosis and matched general population controls in the 5 years before the first demyelinating disease claim (health administrative index date) or clinically reported symptom onset (clinical index date)...
April 20, 2017: Lancet Neurology
https://www.readbyqxmd.com/read/28238712/the-prion-model-for-progression-and-diversity-of-neurodegenerative-diseases
#2
REVIEW
Barbara E Stopschinski, Marc I Diamond
The neuropathology of different neurodegenerative diseases begins in different brain regions, and involves distinct brain networks. Evidence indicates that transcellular propagation of protein aggregation, which is the basis of prion disease, might underlie the progression of pathology in neurodegenerative diseases such as Alzheimer's disease, Parkinson's disease, and Huntington's disease. The prion model predicts specific patterns of neuronal vulnerability and network involvement on the basis of the conformation of pathological proteins...
February 23, 2017: Lancet Neurology
https://www.readbyqxmd.com/read/28238710/solving-the-conundrum-of-insoluble-protein-aggregates
#3
Sonia George, Patrik Brundin
No abstract text is available yet for this article.
February 23, 2017: Lancet Neurology
https://www.readbyqxmd.com/read/28222966/selective-sodium-channel-blockers-in-trigeminal-neuralgia
#4
Troels Staehelin Jensen
No abstract text is available yet for this article.
February 17, 2017: Lancet Neurology
https://www.readbyqxmd.com/read/28190752/henrik-zetterberg-biomarking-neurological-disorders
#5
Tony Kirby
No abstract text is available yet for this article.
February 9, 2017: Lancet Neurology
https://www.readbyqxmd.com/read/28187920/holter-electrocardiogram-monitoring-in-patients-with-acute-ischaemic-stroke-find-afrandomised-an-open-label-randomised-controlled-trial
#6
Rolf Wachter, Klaus Gröschel, Götz Gelbrich, Gerhard F Hamann, Pawel Kermer, Jan Liman, Joachim Seegers, Katrin Wasser, Anna Schulte, Falko Jürries, Anna Messerschmid, Nico Behnke, Sonja Gröschel, Timo Uphaus, Anne Grings, Tugba Ibis, Sven Klimpe, Michaela Wagner-Heck, Magdalena Arnold, Evgeny Protsenko, Peter U Heuschmann, David Conen, Mark Weber-Krüger
BACKGROUND: Atrial fibrillation is a major risk factor for recurrent ischaemic stroke, but often remains undiagnosed in patients who have had an acute ischaemic stroke. Enhanced and prolonged Holter-electrocardiogram-monitoring might increase detection of atrial fibrillation. We therefore investigated whether enhanced and prolonged rhythm monitoring was better for detection of atrial fibrillation than standard care procedures in patients with acute ischaemic stroke. METHODS: Find-AFRANDOMISED is an open-label randomised study done at four centres in Germany...
February 8, 2017: Lancet Neurology
https://www.readbyqxmd.com/read/28159524/corrections
#7
(no author information available yet)
No abstract text is available yet for this article.
January 31, 2017: Lancet Neurology
https://www.readbyqxmd.com/read/28139348/blockade-of-the-neurite-outgrowth-inhibitor-nogo-a-in-amyotrophic-lateral-sclerosis
#8
Anne-Marie Wills
No abstract text is available yet for this article.
January 28, 2017: Lancet Neurology
https://www.readbyqxmd.com/read/28414653/increasing-value-and-reducing-waste-in-stroke-research
#9
REVIEW
Eivind Berge, Rustam Al-Shahi Salman, H Bart van der Worp, Christian Stapf, Peter Sandercock, Nikola Sprigg, Malcolm R Macleod, Peter J Kelly, Paul J Nederkoorn, Gary A Ford
Stroke is a major burden to patients and society, and resources spent on stroke research must be used efficiently and produce good value in terms of improvements in human health. However, many instances of poor value from stroke research funding have resulted from the way in which stroke research topics have been chosen and how studies have been designed, conducted, analysed, regulated, managed, disseminated, or reported. A cooperative effort of European stroke researchers aimed to identify sources of inefficiency and waste, recommend approaches to increase value, and highlight examples of best practice in stroke research...
May 2017: Lancet Neurology
https://www.readbyqxmd.com/read/28414652/no-past-no-future-studies-in-the-art-and-science-of-memory
#10
Jules Morgan
No abstract text is available yet for this article.
May 2017: Lancet Neurology
https://www.readbyqxmd.com/read/28414651/historical-landmarks-in-dementia-with-lewy-bodies
#11
Christoph Mueller, Clive Ballard, Anne Corbett, Dag Aarsland
No abstract text is available yet for this article.
May 2017: Lancet Neurology
https://www.readbyqxmd.com/read/28414650/edor-kabashi
#12
(no author information available yet)
No abstract text is available yet for this article.
May 2017: Lancet Neurology
https://www.readbyqxmd.com/read/28414649/gaining-ground-against-cerebral-malaria
#13
Adrian Burton
No abstract text is available yet for this article.
May 2017: Lancet Neurology
https://www.readbyqxmd.com/read/28414648/r%C3%A3-mi-w-bouchard-a-pioneer-in-behavioural-neurology
#14
LETTER
Robert Laforce, Louis Verret, Stéphane Poulin, Marie-Pierre Fortin, Michèle Houde
No abstract text is available yet for this article.
May 2017: Lancet Neurology
https://www.readbyqxmd.com/read/28414647/diagnosis-and-classification-of-optic-neuropathies-authors-reply
#15
LETTER
Valerie Biousse, Nancy J Newman
No abstract text is available yet for this article.
May 2017: Lancet Neurology
https://www.readbyqxmd.com/read/28414646/membrane-damage-is-at-the-core-of-alzheimer-s-disease
#16
LETTER
John Hardy
No abstract text is available yet for this article.
May 2017: Lancet Neurology
https://www.readbyqxmd.com/read/28414645/diagnosis-and-classification-of-optic-neuropathies
#17
LETTER
Piergiorgio Lochner, Francesco Brigo, Raffaele Nardone, Martin Lesmeister, Klaus Fassbender
No abstract text is available yet for this article.
May 2017: Lancet Neurology
https://www.readbyqxmd.com/read/28414644/corrections
#18
(no author information available yet)
No abstract text is available yet for this article.
May 2017: Lancet Neurology
https://www.readbyqxmd.com/read/28414643/optimisation-of-stroke-research
#19
Mahmoud Reza Azarpazhooh, Vladimir Hachinski
No abstract text is available yet for this article.
May 2017: Lancet Neurology
https://www.readbyqxmd.com/read/28414642/disease-progression-in-lrrk2-parkinsonism
#20
Marios Politis
No abstract text is available yet for this article.
May 2017: Lancet Neurology
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