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Lancet Infectious Diseases

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https://www.readbyqxmd.com/read/30195997/back-to-chloroquine-for-malaria-prophylaxis-in-pregnancy
#1
R Matthew Chico, Feiko O Ter Kuile
No abstract text is available yet for this article.
September 5, 2018: Lancet Infectious Diseases
https://www.readbyqxmd.com/read/30195996/chloroquine-as-weekly-chemoprophylaxis-or-intermittent-treatment-to-prevent-malaria-in-pregnancy-in-malawi-a-randomised-controlled-trial
#2
Titus H Divala, Randy G Mungwira, Patricia M Mawindo, Osward M Nyirenda, Maxwell Kanjala, Masiye Ndaferankhande, Lufina E Tsirizani, Rhoda Masonga, Francis Muwalo, Gail E Potter, Jessie Kennedy, Jaya Goswami, Blair J Wylie, Atis Muehlenbachs, Lughano Ndovie, Priscilla Mvula, Yamikani Mbilizi, Tamiwe Tomoka, Miriam K Laufer
BACKGROUND: Sulfadoxine-pyrimethamine resistance threatens efficacy of intermittent preventive treatment of malaria during pregnancy, and alternative regimens need to be identified. With the return of chloroquine efficacy in southern Africa, we postulated that chloroquine either as an intermittent therapy or as weekly chemoprophylaxis would be more efficacious than intermittent sulfadoxine-pyrimethamine for prevention of malaria in pregnancy and associated maternal and newborn adverse outcomes...
September 5, 2018: Lancet Infectious Diseases
https://www.readbyqxmd.com/read/30195995/deliberations-of-the-strategic-advisory-group-of-experts-on-immunization-on-the-use-of-cyd-tdv-dengue-vaccine
#3
REVIEW
Annelies Wilder-Smith, Joachim Hombach, Neil Ferguson, Michael Selgelid, Kate O'Brien, Kirsten Vannice, Alan Barrett, Elizabeth Ferdinand, Stefan Flasche, Maria Guzman, Hillegonde Maria Novaes, Lee-Ching Ng, Peter G Smith, Piyanit Tharmaphornpilas, In-Kyu Yoon, Alejandro Cravioto, Jeremy Farrar, Terry M Nolan
The Strategic Advisory Group of Experts (SAGE) on Immunization advises WHO on global policies for vaccines. In April, 2016, SAGE issued recommendations on the use of the first licenced dengue vaccine, CYD-TDV. In November, 2017, a retrospective analysis of clinical trial data, stratifying participants according to their dengue serostatus before the first vaccine dose, showed that although in high seroprevalence settings the vaccine provides overall population benefit, there was an excess risk of severe dengue in seronegative vaccinees...
September 5, 2018: Lancet Infectious Diseases
https://www.readbyqxmd.com/read/30195994/corrections
#4
(no author information available yet)
No abstract text is available yet for this article.
September 5, 2018: Lancet Infectious Diseases
https://www.readbyqxmd.com/read/30194037/enterococcus-faecium-tolerance-to-isopropanol-from-good-science-to-misinformation
#5
LETTER
Didier Pittet, Alexandra Peters, Ermira Tartari
No abstract text is available yet for this article.
September 4, 2018: Lancet Infectious Diseases
https://www.readbyqxmd.com/read/30190197/corrections
#6
(no author information available yet)
No abstract text is available yet for this article.
September 3, 2018: Lancet Infectious Diseases
https://www.readbyqxmd.com/read/30174209/prognostic-value-of-interferon-%C3%AE-release-assays-and-tuberculin-skin-test-in-predicting-the-development-of-active-tuberculosis-uk-predict-tb-a-prospective-cohort-study
#7
Ibrahim Abubakar, Francis Drobniewski, Jo Southern, Alice J Sitch, Charlotte Jackson, Marc Lipman, Jonathan J Deeks, Chris Griffiths, Graham Bothamley, William Lynn, Helen Burgess, Bobby Mann, Ambreen Imran, Saranya Sridhar, Chuen-Yan Tsou, Vladyslav Nikolayevskyy, Melanie Rees-Roberts, Hilary Whitworth, Onn Min Kon, Pranab Haldar, Heinke Kunst, Sarah Anderson, Andrew Hayward, John M Watson, Heather Milburn, Ajit Lalvani
BACKGROUND: Tackling tuberculosis requires testing and treatment of latent tuberculosis in high-risk groups. The aim of this study was to estimate the predictive values of the tuberculin skin test (TST) and two interferon-γ release assays (IGRAs) for the development of active tuberculosis in high-risk groups-ie, people in recent contact with active tuberculosis cases and from high-burden countries. METHOD: In this prospective cohort study, we recruited participants from 54 centres (eg, clinics, community settings) in London, Birmingham, and Leicester in the UK...
August 30, 2018: Lancet Infectious Diseases
https://www.readbyqxmd.com/read/30174208/predicting-tuberculosis-the-blood-the-skin-or-the-sibyl
#8
Jean-Pierre Zellweger
No abstract text is available yet for this article.
August 30, 2018: Lancet Infectious Diseases
https://www.readbyqxmd.com/read/30172580/quantifying-drivers-of-antibiotic-resistance-in-humans-a-systematic-review
#9
REVIEW
Anuja Chatterjee, Maryam Modarai, Nichola R Naylor, Sara E Boyd, Rifat Atun, James Barlow, Alison H Holmes, Alan Johnson, Julie V Robotham
Mitigating the risks of antibiotic resistance requires a horizon scan linking the quality with the quantity of data reported on drivers of antibiotic resistance in humans, arising from the human, animal, and environmental reservoirs. We did a systematic review using a One Health approach to survey the key drivers of antibiotic resistance in humans. Two sets of reviewers selected 565 studies from a total of 2819 titles and abstracts identified in Embase, MEDLINE, and Scopus (2005-18), and the European Centre for Disease Prevention and Control, the US Centers for Disease Control and Prevention, and WHO (One Health data)...
August 29, 2018: Lancet Infectious Diseases
https://www.readbyqxmd.com/read/30170987/typhoid-conjugate-vaccines-a-new-tool-in-the-fight-against-antimicrobial-resistance
#10
REVIEW
Jason R Andrews, Stephen Baker, Florian Marks, Marcella Alsan, Denise Garrett, Bruce G Gellin, Samir K Saha, Farah Naz Qamar, Mohammad Tahir Yousafzai, Isaac I Bogoch, Marina Antillon, Virginia E Pitzer, Jong-Hoon Kim, Jacob John, Jillian Gauld, Vittal Mogasale, Edward T Ryan, Stephen P Luby, Nathan C Lo
Typhoid fever is an acute systemic infectious disease responsible for an estimated 12-20 million illnesses and over 150 000 deaths annually. In March, 2018, a new recommendation was issued by WHO for the programmatic use of typhoid conjugate vaccines in endemic countries. Health economic analyses of typhoid vaccines have informed funding decisions and national policies regarding vaccine rollout. However, by focusing only on averted typhoid cases and their associated costs, traditional cost-effectiveness analyses might underestimate crucial benefits of typhoid vaccination programmes, because the potential effect of typhoid vaccines on the treatment of patients with non-specific acute febrile illnesses is not considered...
August 28, 2018: Lancet Infectious Diseases
https://www.readbyqxmd.com/read/30170986/assessment-of-ultra-sensitive-malaria-diagnosis-versus-standard-molecular-diagnostics-for-malaria-elimination-an-in-depth-molecular-community-cross-sectional-study
#11
Natalie E Hofmann, Maria Gruenberg, Elma Nate, Alice Ura, Daniela Rodriguez-Rodriguez, Mary Salib, Ivo Mueller, Thomas A Smith, Moses Laman, Leanne J Robinson, Ingrid Felger
BACKGROUND: Submicroscopic malaria infections contribute to transmission in exposed populations but their extent is underestimated even by standard molecular diagnostics. Sophisticated sampling and ultra-sensitive molecular methods can maximise test sensitivity but are not feasible in routine surveillance. Here we investigate the gains achievable by using increasingly sensitive methods with the aim to understand what diagnostic sensitivity is necessary to guide malaria interventions. METHODS: Venous blood samples were collected from participants in a cross-sectional survey in two coastal medium-endemic villages in Madang province, Papua New Guinea...
August 28, 2018: Lancet Infectious Diseases
https://www.readbyqxmd.com/read/30170985/are-ultra-sensitive-molecular-tools-needed-to-detect-malaria-transmitters
#12
Anna Rosanas-Urgell, Johanna Helena Kattenberg
No abstract text is available yet for this article.
August 28, 2018: Lancet Infectious Diseases
https://www.readbyqxmd.com/read/30146320/burden-of-hiv-associated-histoplasmosis-compared-with-tuberculosis-in-latin-america-a-modelling-study
#13
Antoine A Adenis, Audrey Valdes, Claire Cropet, Orion Z McCotter, Gordana Derado, Pierre Couppie, Tom Chiller, Mathieu Nacher
BACKGROUND: Fungal infections remain a major contributor to the opportunistic infections that affect people living with HIV. Among them, histoplasmosis is considered neglected, often being misdiagnosed as tuberculosis, and is responsible for numerous deaths in Latin America. The objective of this study was to estimate the burden of HIV-associated histoplasmosis compared with tuberculosis in Latin American countries. METHODS: For this modelling study, we estimated prevalence of previous exposure to Histoplasma capsulatum, HIV-associated histoplasmosis annual incidence, and number of deaths in 2012 in Latin American countries based on historical histoplasmin skin test studies in the general population, with an antigen dilution level of more than 1/10...
August 23, 2018: Lancet Infectious Diseases
https://www.readbyqxmd.com/read/30146319/histoplasmosis-dethrones-tuberculosis-in-latin-america
#14
Alessandro C Pasqualotto, Flavio Quieroz-Telles
No abstract text is available yet for this article.
August 23, 2018: Lancet Infectious Diseases
https://www.readbyqxmd.com/read/30126644/patterns-in-the-epidemic-of-escherichia-coli-bloodstream-infection-in-oxfordshire
#15
David R Jenkins
No abstract text is available yet for this article.
August 17, 2018: Lancet Infectious Diseases
https://www.readbyqxmd.com/read/30126643/trends-over-time-in-escherichia-coli-bloodstream-infections-urinary-tract-infections-and-antibiotic-susceptibilities-in-oxfordshire-uk-1998-2016-a-study-of-electronic-health-records
#16
Karina-Doris Vihta, Nicole Stoesser, Martin J Llewelyn, T Phuong Quan, Tim Davies, Nicola J Fawcett, Laura Dunn, Katie Jeffery, Chris C Butler, Gail Hayward, Monique Andersson, Marcus Morgan, Sarah Oakley, Amy Mason, Susan Hopkins, David H Wyllie, Derrick W Crook, Mark H Wilcox, Alan P Johnson, Tim E A Peto, A Sarah Walker
BACKGROUND: Escherichia coli bloodstream infections are increasing in the UK and internationally. The evidence base to guide interventions against this major public health concern is small. We aimed to investigate possible drivers of changes in the incidence of E coli bloodstream infection and antibiotic susceptibilities in Oxfordshire, UK, over the past two decades, while stratifying for time since hospital exposure. METHODS: In this observational study, we used all available data on E coli bloodstream infections and E coli urinary tract infections (UTIs) from one UK region (Oxfordshire) using anonymised linked microbiological data and hospital electronic health records from the Infections in Oxfordshire Research Database (IORD)...
August 17, 2018: Lancet Infectious Diseases
https://www.readbyqxmd.com/read/30122439/sustainable-access-to-deworming-drugs-in-a-changing-landscape
#17
REVIEW
William M Lin, David G Addiss
The global effort to control and eliminate soil-transmitted helminthiasis (STH) currently depends on donations of albendazole and mebendazole, which reached more than 530 million children in 2016. As we approach 2020, the WHO goal of eliminating STH as a public health problem will not be met in most endemic countries, and ongoing treatment will be necessary. Additionally, the volume of drugs required might increase because global strategies for STH aim to interrupt transmission. Under the 2012 London Declaration on Neglected Tropical Diseases, pharmaceutical company commitments to donate drugs to control or eliminate neglected tropical diseases extend to 2020...
August 16, 2018: Lancet Infectious Diseases
https://www.readbyqxmd.com/read/30120070/nmcv-5-meningococcal-vaccine-neisseria-meningitidis-nemesis
#18
Marie-Pierre Preziosi, Brian Greenwood
No abstract text is available yet for this article.
August 14, 2018: Lancet Infectious Diseases
https://www.readbyqxmd.com/read/30120069/safety-and-immunogenicity-of-a-pentavalent-meningococcal-conjugate-vaccine-containing-serogroups-a-c-y-w-and-x-in-healthy-adults-a-phase-1-single-centre-double-blind-randomised-controlled-study
#19
Wilbur H Chen, Kathleen M Neuzil, C Rebecca Boyce, Marcela F Pasetti, Mardi K Reymann, Lionel Martellet, Nancy Hosken, F Marc LaForce, Rajeev M Dhere, Sambhaji S Pisal, Amol Chaudhari, Prasad S Kulkarni, Ray Borrow, Helen Findlow, Valerie Brown, Megan L McDonough, Len Dally, Mark R Alderson
BACKGROUND: Invasive meningococcal disease is an important public health problem, especially in sub-Saharan Africa. After introduction of MenAfriVac in 2010, Neisseria meningitidis serogroup A disease has been almost eliminated from the region. However, serogroups C, W, Y, and X continue to cause disease outbreaks. We assessed the NmCV-5 pentavalent meningococcal conjugate vaccine targeting A, C, Y, W, and X serogroups in a first-in-man, phase 1 study. METHODS: We did a single-centre, double-blind, randomised controlled trial at a research clinic in Baltimore (MD, USA)...
August 14, 2018: Lancet Infectious Diseases
https://www.readbyqxmd.com/read/30078662/global-burden-of-recurrent-vulvovaginal-candidiasis-a-systematic-review
#20
REVIEW
David W Denning, Matthew Kneale, Jack D Sobel, Riina Rautemaa-Richardson
Recurrent vulvovaginal candidiasis is a debilitating, long-term condition that can severely affect the quality of life of affected women. No estimates of the global prevalence or lifetime incidence of this disease have been reported. For this systematic review, we searched PubMed, Embase, and Web of Science databases for population-based studies published between 1985 and 2016 that reported on the prevalence of recurrent vulvovaginal candidiasis, defined as four or more episodes of the infection every year...
August 2, 2018: Lancet Infectious Diseases
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