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Journal of Surgical Research

Mathieu C Raillard, Shannon M Axiak Flammer, Claudia Spadavecchia
No abstract text is available yet for this article.
January 8, 2018: Journal of Surgical Research
Karim Hamaoui, Sally Gowers, Bynvant Sandhu, Natalie Vallant, Terry Cook, Martyn Boutelle, Daniel Casanova, Vassilios Papalois
BACKGROUND: Hypothermic machine perfusion (HMP) is increasingly being used for extended criteria kidney grafts. Pancreatic HMP is challenging because physiologically the pancreas is a low-flow organ susceptible to edema. We report the successful development of preclinical HMP models using porcine pancreases, as well as human pancreases unsuitable for clinical transplantation. METHODS: Ten porcine pancreases were used in the development of these perfusion models...
January 8, 2018: Journal of Surgical Research
Chunyi Kan, Anding Liu, Haoshu Fang, Olaf Dirsch, Uta Dahmen, Michael Boettcher
No abstract text is available yet for this article.
January 3, 2018: Journal of Surgical Research
Jason M Weissler, Martin J Carney, Fabiola A Enriquez, Charles A Messa, Robyn Broach, Marilyn M Shapira, Frances K Barg, John P Fischer
BACKGROUND: Prophylactic mesh placement (PMP) at the time of open abdominal surgery has gained momentum over the last decade. However, there remains an identifiable gap in the literature regarding patient-reported outcomes and qualitative metrics. In effort to gauge the population's understanding or familiarity with PMP, this study provides an educational framework and uses crowdsourcing as a novel means to assess perception among the general population. METHODS: A cross-sectional survey study was conducted among the general public to elicit perspectives on PMP...
December 29, 2017: Journal of Surgical Research
David Krpata
No abstract text is available yet for this article.
December 19, 2017: Journal of Surgical Research
Efthimios D Avgerinos, Georgia Kostopanagiotou, Kostas Kostopanagiotou, Nikolaos Kopanakis, Ioanna Andreadou, Marilena Lekka, George Nakos, Vasilios Smyrniotis
No abstract text is available yet for this article.
December 9, 2017: Journal of Surgical Research
Chelsea Williams, Raquel Weston, Joe Feinglass, Marie Crandall
BACKGROUND: Bicycling is one of the most popular forms of play and exercise for children in the US. However, over 200,000 children per year are injured in bicycle crashes, and an estimated 22,000 pediatric bicycle-related traumatic brain injuries (TBIs) occur annually. Bicycle helmets are known to decrease the risk of head injury, but efficacy and magnitude of the effect of helmet legislation have not been fully elucidated. METHODS: This was a retrospective, observational study of children aged <18, who presented after a bicycle crash in Illinois from 1999 to 2009...
December 8, 2017: Journal of Surgical Research
Katherine McKendy, Lawrence Lee, Jeremy Grushka
No abstract text is available yet for this article.
December 4, 2017: Journal of Surgical Research
Christopher B Horn, Dajun Tian, Grant V Bochicchio, Isaiah R Turnbull
BACKGROUND: Appendicitis is the most common intraabdominal surgical emergency in the United States, with over 250,000 cases each year. Several recent studies have evaluated the efficacy of nonoperative management of appendicitis. We measured changes in the treatment of appendicitis in the United States from 1998 to 2014 and evaluated outcomes in the contemporary cohort of appendicitis cases from 2010 to 2014. METHODS: The National Inpatient Sample was queried for cases with a principal diagnosis of appendicitis...
December 1, 2017: Journal of Surgical Research
Michelle M Amaral, William E Herrin, Jonathan M Saxe, Lewis E Jacobson, Courtney D Jensen
No abstract text is available yet for this article.
November 30, 2017: Journal of Surgical Research
Shailendra Kapoor
No abstract text is available yet for this article.
November 25, 2017: Journal of Surgical Research
Richard S Cartabuke, Joseph D Tobias, Julie Rice, Dmitry Tumin
BACKGROUND: Considerable variation in the perioperative management of infants with pyloric stenosis (PS) led the authors to undertake a survey of pediatric anesthesiologists to determine if consensus-based guidelines could be developed. MATERIALS AND METHODS: Physicians who are members of the Society for Pediatric Anesthesia or the Association of Pediatric Anaesthetists of Great Britain and Ireland completed an online questionnaire through SurveyMonkey regarding current management of patients with PS...
November 17, 2017: Journal of Surgical Research
Tyler J Loftus, Scott C Brakenridge, Chasen A Croft, R Stephen Smith, Philip A Efron, Frederick A Moore, Alicia M Mohr, Janeen R Jordan
BACKGROUND: Our objective was to identify predictors of successful nonoperative management (NOM) of uncomplicated appendicitis. We hypothesized that the absence of diabetes, absence of an appendicolith, short duration of symptoms, absence of systemic inflammation, and low modified Alvarado score would predict successful NOM. METHODS: We performed a retrospective cohort analysis of 81 consecutive patients who underwent NOM of uncomplicated appendicitis. Successful NOM was defined as resolution of appendicitis with antibiotics alone and no recurrent appendicitis within 180 days...
November 13, 2017: Journal of Surgical Research
Catherine W Lancaster, Charles DiMaggio, Gary Marshall, Stephen Wall, Patricia Ayoung-Chee
BACKGROUND: Twenty-five percent of trauma patients are discharged to postacute care, indicating a loss of physical function and need for rehabilitation. The purpose of this study was to quantify the functional improvements in trauma patients discharged from inpatient rehabilitation facility (IRF) and identify predictors of improvement. MATERIALS AND METHODS: A retrospective cohort study of trauma patients aged ≥ 18 years were admitted to an IRF after discharge from a level-1 trauma center...
November 2, 2017: Journal of Surgical Research
Steven Craig Vranian, Kelly L Covert, Caitlin R Mardis, John W McGillicuddy, Kenneth D Chavin, Derek Dubay, David J Taber
BACKGROUND: There are only a limited number of studies that have sought to identify patients at high risk for medication errors and subsequent adverse clinical outcomes. This study sought to identify risk factors for increased health care resource utilization in kidney transplant recipients based on drug-related problems and self-administered surveys. METHODS: In this prospective observational study, adult kidney transplant recipients seen in the transplant clinic between September and November 2015 were surveyed for self-reported demographics, medication adherence, and health status/outlook...
October 31, 2017: Journal of Surgical Research
Alexander S Chiu, Raymond A Jean, Jolanta Gorecka, Kimberly A Davis, Kevin Y Pei
BACKGROUND: Many believe that the use of ureteral stents in colorectal surgery for diverticulitis aids prevention and easier identification of ureteral injuries; others argue that the added time, cost, and risks of stent placement negate potential benefits. Even among providers who use stents, selective use is common. Among unclear consensus, it remains unknown if the use of stents is growing. MATERIALS: Patients in the National Inpatient Sample who underwent a partial colectomy or anterior rectal excision for diverticulitis between 2000 and 2013 were included (n = 811,071)...
October 31, 2017: Journal of Surgical Research
Tyler J Loftus, Janeen R Jordan
No abstract text is available yet for this article.
October 27, 2017: Journal of Surgical Research
Wei-Jie Zhang, Xiao-Hua Wang, Shao-Ting Gao, Cheng Chen, Xin-Yun Xu, Qi Sun, Zhi-Hua Zhou, Guo-Zhong Wu, Qiao Yu, Guifang Xu, Yong-Zhong Yao, Wen-Xian Guan
BACKGROUND: Tumor-associated macrophages (TAMs) are associated with poor outcomes in multiple solid cancers and play important roles in cancer progression. Epithelial-mesenchymal transition (EMT) may account for metastasis and recurrence. However, the association between TAMs and EMT is not clarified in triple-negative breast cancer (TNBC). The aim of this study was to investigate the effects of TAMs on EMT in TNBC. MATERIAL AND METHODS: We studied specimens from 278 patients with TNBC...
February 2018: Journal of Surgical Research
Roman Marius Eickhoff, Andreas Kroh, Klaus Rübsamen, Daniel Heise, Marcel Binnebösel, Uwe Klinge, Ulf Peter Neumann, Christian Daniel Klink
BACKGROUND: Abdominal adhesions are one of the most common complications after abdominal surgery, and fibrin is suspected to be a crucial component. The aim of the current study was an in vivo evaluation of a new recombinant fibrinogenase (AK03) in two animal models. METHODS: Sixty-four rats were randomly divided into four groups (sodium chloride [NaCl], icodextrin, AK03 low dose, and AK03 high dose) and evaluated at two time endpoints. Adhesion model comprised both a visceral defect (terminal ileum) and parietal defect...
February 2018: Journal of Surgical Research
Wenjuan Sun, Shuhong Duan, Gang Xin, Juan Xiao, Fanzhen Hong, Haijie Hong, Yuange Wu, Yongping Xu
BACKGROUND: With the increase of cesarean deliveries globally, the incidence of placenta adhesive disorder has been on the rise greatly which is associated closely with maternal and infant morbidity and mortality. We sought to investigate the safety and efficacy of preoperative transfemoral balloon occlusion of abdominal aorta in cesarean section of women with placenta increta or percreta. METHODS: We conducted a retrospective study of 31 patients with placenta increta or percreta diagnosed by ultrasound and/or magnetic resonance imaging...
February 2018: Journal of Surgical Research
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