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Journal of Surgical Research

Barbara C Cahill, Sanjeev Raman, John R Stringham, Stephen H McKellar, Craig H Selzman, Theodore G Liou
No abstract text is available yet for this article.
September 4, 2018: Journal of Surgical Research
Stephen A Castellanos, Gerardo Buentello, Diana Gutierrez-Meza, Angela Forgues, Lisa Haubert, Avo Artinyan, Cameron L Macdonald, James W Suliburk
No abstract text is available yet for this article.
August 30, 2018: Journal of Surgical Research
Kyoko Okada, Motohiro Sekino, Hiroyuki Funaoka, Shuntaro Sato, Taiga Ichinomiya, Hiroaki Murata, Takuji Maekawa, Masaharu Nishikido, Kiyoyuki Eishi, Tetsuya Hara
BACKGROUND: Intestinal fatty acid-binding protein (I-FABP), a biomarker of enterocyte injury, has been reported to be a diagnostic marker of intestinal ischemia and a prognostic marker in critically ill patients. However, the kinetics of I-FABP in renal failure patients is unknown. We sought to identify I-FABP levels in patients with chronic kidney disease (CKD) and end-stage kidney disease (ESKD) on hemodialysis (HD) and to identify the manner in which the I-FABP levels change. MATERIALS AND METHODS: Adult patients who were admitted for elective cardiac surgery with either normal renal function (NRF), CKD, or ESKD on HD were enrolled...
October 2018: Journal of Surgical Research
Heather Carmichael, Ethan Jamison, Kirk A Bol, Robert McIntyre, Catherine G Velopulos
BACKGROUND: Intimate partner violence (IPV) is prevalent but underrecognized; at least 25% of United States women experience IPV within their lifetime. We examined the most severe consequence of IPV by exploring the patterns of death from IPV in a statewide database of homicide victims. MATERIALS AND METHODS: This is a retrospective review of the Colorado Violent Death Reporting System from 2004 to 2015. Deaths were coded as IPV if the primary relationship between the suspect and victim fell into the following categories: spouse, ex-spouse, girlfriend/boyfriend, and ex-girlfriend/ex-boyfriend...
October 2018: Journal of Surgical Research
Nicholas Sellke, Caroline Gordon, Isabella Lawandy, Anastassia Y Gorvitovskaia, Laura A Scrimgeour, James G Fingleton, Frank W Sellke, Jun Feng
BACKGROUND: We have previously found that hyperkalemic cardioplegic arrest in the setting of cardiopulmonary bypass (CP/CPB) is associated with impairment of the coronary arteriolar response to phenylephrine in nondiabetic (ND) patients. We hypothesized that diabetes may alter coronary arteriolar response to alpha-1 adrenergic agonist in the setting of CP/CPB. In this study, we further investigated the effects of diabetes on the altered coronary arteriolar response to phenylephrine in patients undergoing cardiac surgery...
October 2018: Journal of Surgical Research
Austin D Williams, Yun R Li, Alycia So, Laura Steel, Elena Carrigan, Vicky Ro, Jenny Nguyen, Julia Tchou
BACKGROUND: The use of aspirin has been associated with improved survival in patients with breast cancer, but the results have been mixed. We aim to analyze the impact of aspirin use before or after breast cancer diagnosis on breast cancer clinical characteristics and outcomes. MATERIALS AND METHODS: We performed a single-institution, retrospective analysis of 1113 women diagnosed with operable breast cancer between 1995 and 2015. Patients were grouped according to their aspirin use: never (944), before diagnosis (79), and after diagnosis (90)...
October 2018: Journal of Surgical Research
Ramon Diez-Barroso, Carlos H Palacio, Julian A Martinez, Konstantinos Makris, Nader N Massarweh, Christy Y Chai, Samir S Awad, Hop S Tran Cao
BACKGROUND: With the increasing use of the robotic platform in general surgery, whether 8-mm ports should be closed comes into question. We sought to characterize the incidence of port-site hernias (PSHs) among patients undergoing robotic-assisted general surgery. METHODS: A retrospective chart review of a single institutional database identified patients who underwent robotic-assisted general surgery from July 2010 to December 2016. For each patient, the number, type, location, and size of all ports were collected...
October 2018: Journal of Surgical Research
Courtney J Balentine, Meredith C Mason, Peter J Richardson, Panagiotis Kougias, Faisal Bakaeen, Aanand D Naik, David H Berger, Daniel A Anaya
BACKGROUND: Variation in use of postacute care (PAC), including skilled nursing facilities and inpatient rehabilitation, accounts for 73% of regional variation in Medicare spending. Studies of hospital variation in PAC use have typically focused on nonsurgical patients or have been limited to Medicare data. Consequently, there is no nationally representative data on how rates of postoperative discharge to PAC differ between hospitals. The purpose of this study was to explore hospital-level variation in PAC utilization after cardiovascular and abdominal surgery...
October 2018: Journal of Surgical Research
Noriyuki Hirahara, Yoshitsugu Tajima, Yusuke Fujii, Ryoji Hyakudomi, Tetsu Yamamoto, Kazunari Ishitobi, Takahito Taniura, Yasunari Kawabata
BACKGROUND: Red cell distribution width (RDW) is routinely assessed as part of the complete blood count (CBC) to gather information on the heterogeneity in the size of circulating erythrocytes. RDW is a more sensitive screening marker for anemia, inflammation, and nutritional deficiencies. The purpose of this study was to explore the prognostic value of RDW in esophageal squamous cell carcinoma (ESCC) patients. METHODS: We conducted a retrospective study of data from 148 ESCC consecutive patients who underwent potentially curative esophagectomy and analyzed the correlation of RDW with various clinicopathological factors...
October 2018: Journal of Surgical Research
Melissa L Mao, Thomas Joyal, Omar Picado, Darcy Kerr, John I Lew, Josefina C Farrá
BACKGROUND: The reclassification of noninvasive encapsulated follicular variant papillary thyroid carcinoma (FVPTC) to noninvasive follicular thyroid neoplasm with papillary-like nuclear features (NIFTP) may have significant implications by changing overall malignancy rates and minimizing the extent of surgical treatment. METHODS: A retrospective review of 847 patients who underwent thyroidectomy at a single institution from January 2010 to April 2016 was performed...
October 2018: Journal of Surgical Research
Sarah B Cairo, George Ventro, Ellene Sandoval, David H Rothstein
BACKGROUND: The purpose of this study is to describe a cohort of pediatric patients undergoing cholecystectomy for biliary dyskinesia (BD) and characterize postoperative resource utilization. METHODS: Single-institution, retrospective chart review of pediatric patients after cholecystectomy for BD was done. Patient demographics and clinical characteristics as well as operative details and postoperative interventions were abstracted. Telephone follow-up was performed to identify persistent symptoms, characterize the patient experience, and quantify postoperative resource utilization...
October 2018: Journal of Surgical Research
Hubert Y Luu, Eric D Wang, Shareef M Syed, Xiaoti Xu, Scott L Hansen, Charles M Eichler, Eric K Nakakura
BACKGROUND: Current surgical management of retroperitoneal masses involving major vessels now includes complete en bloc resection with in situ venous, arterial, or combined reconstruction. No studies have investigated preresection arterial bypass for continuous lower extremity perfusion during definitive resection. Here, we characterize and compare the outcomes of surgery for retroperitoneal masses with major vascular involvement by a two-stage approach (femoral-femoral bypass preceding resection) and the traditional one-stage approach (consecutive resection and in situ vascular reconstruction)...
October 2018: Journal of Surgical Research
Brian Ezekian, Mohamad A Adam, Megan C Turner, Brian F Gilmore, Kyle Freischlag, Harold J Leraas, Christopher R Mantyh, John Migaly
BACKGROUND: Controversy exists regarding current National Comprehensive Cancer Network guidelines, which recommend local excision for rectal carcinoids ≤2 cm and radical resection for tumors >2 cm. Given the limited data examining optimal surgical approach for these lesions, we queried a national database to determine the impact of extent of resection on survival. METHODS: Patients undergoing treatment for clinical stage I and II rectal carcinoid (RC) were identified from the National Cancer Data Base (1998-2012)...
October 2018: Journal of Surgical Research
Alexander Bonde, Rasmus Kirial, Peter Svenningsen, Martin Sillesen
BACKGROUND: Despite initial lifesaving benefits, posttraumatic resuscitation strategies have been associated with immunologic complications leading to systemic inflammatory response syndrome, sepsis, multiple organ failure, and late trauma death. Nevertheless, the direct effect on immunologic surface markers remains inadequately described. We hypothesized that changes in monocyte and T-cell surface markers were associated with initial posttraumatic fluid resuscitation. MATERIALS AND METHODS: Data were extracted from the inflammation and host response to injury (Glue Grant) study...
October 2018: Journal of Surgical Research
Xuehan Li, Yi Xu, Yan Cheng, Rurong Wang
BACKGROUND: Activation of transient receptor potential vanilloid type 1 (TRPV1) decreases lung ischemia-reperfusion injury (LIRI) in rabbits and rats. Stimulation of α7 nicotinic acetylcholine receptors (α7nAChRs) protects against lung injury. Here we examined whether α7nAChRs contribute to TRPV1-mediated protection against LIRI. METHODS: Wild-type (WT) and TRPV1-knockout (KO) mice were subjected to 1-h lung ischemia by clamping left hilum, followed by 2-h reperfusion...
October 2018: Journal of Surgical Research
Annika Winsnes, Ulf Gunnarsson, Peter Falk, Birgit Stark, Jan Ø Moskaug, Karin Strigård
BACKGROUND: Importance: Hernia surgery requires reinforcement material with few side effects when used in the intraperitoneal position. Autologous skin grafting may meet this requirement, but animal experiments are obligatory before being applied in humans. OBJECTIVE: To compare survival and effects of isogeneic full-thickness skin grafts in the intraperitoneal onlay mesh (IPOM) position in mice, with a control group using the onlay position. Primary end point was graft survival and secondary end point adhesion formation and inflammation through NF-κB activity...
October 2018: Journal of Surgical Research
Andrew J Lee, Yi-Ju Chiang, Jeffrey E Lee, Claudius Conrad, Yun-Shin Chun, Thomas A Aloia, Jean-Nicolas Vauthey, Ching-Wei D Tzeng
BACKGROUND: For gallbladder cancer (GBC), the American Joint Committee on Cancer eighth edition (AJCC 8) staging system classifies lymph node (LN) stage by the number of positive LN and recommends sampling of ≥6 LNs. We evaluated the prognostic capability of the AJCC 8 for patients undergoing resection and the current national trends in LN staging in the context of these new recommendations for nodal (N) sampling. METHODS: Utilizing the National Cancer Data Base, we identified all gallbladder adenocarcinoma patients treated with surgical resection in 2004-2014...
October 2018: Journal of Surgical Research
Daniel Ruter, Wei Chen, Ramon Garza, Daniel Eiferman, Roman Skoracki
BACKGROUND: The standard of care for treatment of lymphedema is manual lymphatic drainage and compression therapy, which is time intensive and requires a life-long commitment. Autologous lymph node transfer is a microsurgical treatment in which a vascularized lymph node flap is harvested with its blood supply and transferred to the lymphedematous region to assist with lymph fluid clearance. An ideal donor lymph node site minimizes the risk of iatrogenic lymphedema and other donor site morbidity...
October 2018: Journal of Surgical Research
Stephen Tabiri, Edwin M T Yenli, Frank E Gyamfi, Ali Jalali, Richard E Nelson, Raymond R Price, Micah G Katz
BACKGROUND: Despite the recognition that inguinal hernia (IH) repair is cost-effective, repair rates in low- and middle-income countries remain low. Estimated use of mesh in low- and middle-income countries also remains low despite publications about low-cost, noncommercial mesh. The purpose of our study was to assess the current state of IH repair in the northern and transitional zone of Ghana. MATERIALS AND METHODS: A retrospective review of surgical case logs of IH repairs from 2013 to 2017 in 41 hospitals was performed...
October 2018: Journal of Surgical Research
Leah Schoel, Ilan I Maizlin, Tal Koppelmann, Chinwendu Onwubiko, Michelle Shroyer, Ann Douglas, Robert T Russell
BACKGROUND: Data from the American College of Surgeons National Surgical Quality Improvement Program identified our hospital as an outlier for preoperative computed tomography (CT) use in the diagnosis of acute appendicitis in children. We performed a quality improvement project to reduce this utilization in favor of ultrasound-based diagnoses (ultrasonography [US]) through creation and implementation of an evidence-based appendicitis algorithm. METHODS: Over a 2-y period (1 y preceding and 1 y following institution of the algorithm), the clinical information of all pediatric patients operated on for suspicion of acute appendicitis following imaging studies in our institution was collated...
October 2018: Journal of Surgical Research
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