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Journal of Surgical Research

Kevin N Harrell, Mohammad R Jajja, Lauren M Postlewait, Bahar Memis, Shishir K Maithel, Juan M Sarmiento, N Volkan Adsay, David A Kooby
BACKGROUND: Postoperative pancreatic fistula (POPF) is a potentially debilitating complication following pancreatoduodenectomy (PD). There are limited data correlating pancreatic parenchymal histopathologic features specifically fat and fibrosis content with development of POPF after PD. METHODS: Patients who underwent PD (January 2010-May 2015) with archived pathologic slides were included. Each pancreatic neck transection margin was histologically graded for fat and fibrosis, scored from 0 to 4, and grader was blinded to clinical outcomes...
May 10, 2018: Journal of Surgical Research
Chenglong Wang, Adriana C Panayi, Minqiang Xin
No abstract text is available yet for this article.
April 24, 2018: Journal of Surgical Research
Amy E Lawrence, Brent H Adler, Peter C Minneci
No abstract text is available yet for this article.
April 12, 2018: Journal of Surgical Research
Melanie S Morris, Mary T Hawn
No abstract text is available yet for this article.
April 6, 2018: Journal of Surgical Research
Heather J Logghe, Luke V Selby, Marissa A Boeck, Nikki L Stamp, Jason Chuen, Christian Jones
Social media, Twitter in particular, has emerged as an essential tool for surgeons. In the realm of academic surgery, it enables surgeons to advance the core values of academic surgery, as outlined by the Association for Academic Surgery: inclusion, leadership, innovation, scholarship, and mentorship. This article details the ways in which surgeons are using Twitter to embody these values and how the Twitter account for the Association of Academic Surgeons accomplishes its goal of inspiring and developing young academic surgeons...
April 2, 2018: Journal of Surgical Research
Tyler J Loftus, Janeen R Jordan
No abstract text is available yet for this article.
April 2, 2018: Journal of Surgical Research
Haejin In, Marisa Langdon-Embry, Lauren Gordon, Clyde B Schechter, Judith Wylie-Rosett, Philip E Castle, M Margaret Kemeny, Bruce D Rapkin
BACKGROUND: A questionnaire that distinguishes how variability in gastric cancer prevalence is associated with ethnicity/birth country/immigration/cultural diet along with known risk factors may improve targeting populations for gastric cancer screening in the United States. METHODS: Existing literature was used to identify the item pool. Cluster analysis, focus groups, and cognitive interviewing were used to reduce collinear items and refine the questionnaire...
April 2, 2018: Journal of Surgical Research
Umut Safer, Mustafa Kaplan, Vildan Binay Safer
No abstract text is available yet for this article.
March 31, 2018: Journal of Surgical Research
Zhuqing Rao, Haoming Zhou, Zhengnian Ding
No abstract text is available yet for this article.
March 29, 2018: Journal of Surgical Research
Corey Timmerman, Anny Ochoa Hernandez, Cesar Ortiz, Victor Lopez Huertas, Ricardo Lopez, Sergio Huerta
No abstract text is available yet for this article.
March 28, 2018: Journal of Surgical Research
Reginald Anunobi, Brian A Boone, Nick Cheh, Daolin Tang, Rui Kang, Tara Loux, Michael T Lotze, Herbert J Zeh
BACKGROUND: Inflammation promotes the growth and survival of malignant cells. Inflammation within the tumor microenvironment is a result of damage-associated molecular patterns released by dead or dying cells that provide survival signals to the surrounding cells. It has been proposed that extracellular DNA can act as a damage-associated molecular pattern given the association between circulating DNA and autoimmune diseases. Herein, we demonstrate a novel role for genomic extracellular DNA binding to the Toll-like receptor (TLR)-9 on tumor cells in response to cytotoxic insult...
March 28, 2018: Journal of Surgical Research
Lucas Castro-Alves, Mark C Kendall
No abstract text is available yet for this article.
March 9, 2018: Journal of Surgical Research
Louise S van Galen, Daisy Vedder, Tom Boeije, Wilma Jansen, Nieke E Mullaart-Jansen, Donald L van der Peet, Ralph K L So, Prabath W B Nanayakkara
BACKGROUND: Although unscheduled readmissions are increasingly being used as a quality indicator, only few readmission studies have focused on surgical patient populations. METHODS: An observational study "CURIOS@" was performed at three centers in the Netherlands. Readmitted patients and treating doctors were surveyed to assess the discharge process during index admission and their opinion on predictability and preventability of the readmission. Risk factors associated with predictability and preventability as judged by patients and their doctor were identified...
March 8, 2018: Journal of Surgical Research
Benjamin C James, Briseis Aschebrook-Kilfoy, Michael G White, Megan K Applewhite, Sharone P Kaplan, Peter Angelos, Edwin L Kaplan, Raymon H Grogan
BACKGROUND: Thyroid cancer is the fastest growing malignancy in the United States. Previous studies have shown a decrease in quality of life (QoL) after the treatment of thyroid cancer. To date, there have been no studies assessing physician perceptions regarding how a diagnosis of thyroid cancer affects QoL. Based on this and other findings from our study, we aim to assess physician perceptions on the effect of thyroid cancer on QoL. MATERIALS AND METHODS: Physicians were recruited from two national organizations comprised physicians focusing on thyroid cancer...
June 2018: Journal of Surgical Research
Carly Richards, Kelli Ishihara, Cary Grayson, Michael Lustik, Christopher Yheulon
BACKGROUND: Serum lactate is frequently tested in the emergency department (ED) setting to diagnose visceral ischemia and as a marker of end-organ perfusion. It is highly nonspecific, and levels can be affected by both kidney and liver function. In this retrospective chart review, we aim to demonstrate that serum lactate is overused in the ED setting and predicts resource utilization but not the need for surgical intervention. METHODS: ED records with a chief complaint of "abdominal pain" were queried for the preceding 12 mo...
June 2018: Journal of Surgical Research
Huanrui Hu, Zhoupeng Wu, Jichun Zhao, Jiarong Wang, Bin Huang, Yi Yang, Fei Xiong
BACKGROUND: Hemodialysis is a common treatment for end-stage renal disease, and maintenance of access patency remains a key issue. Angioplasty is recommended as the first choice for access stenosis, but it poses a risk of a high rate of restenosis. Stent graft placement can generate a high patency rate of dialysis access. This study aimed to compare the primary patency of the treatment area and access circuit between stent grafts and angioplasty in dialysis access failure. MATERIALS AND METHODS: Three electronic databases, namely, PubMed, Cochrane Library of Systematic Reviews, and EMBASE, were searched from the database inception to September 2017 without language restriction...
June 2018: Journal of Surgical Research
S Erpulat Ozis, Tamila Akhayeva, Sahika Guner, Sibel S Kilicoglu, Arzu Pampal
BACKGROUND: The aim of the study is to evaluate in vivo and in vitro effects of etanercept, a soluble tumor necrosis factor receptor, on the contractile responses of superior mesenteric artery in an experimental mesenteric ischemia and reperfusion model. MATERIAL AND METHODS: After obtaining animal ethics committee approval, 24 Sprague-Dawley rats were allocated to three groups. Control group (Gr C, n = 6) underwent a sham operation, whereas ischemia/reperfusion and treatment groups underwent 90 min ischemia and 24-h reperfusion (Gr I/R, n = 12; Gr I/R+E, n = 6)...
June 2018: Journal of Surgical Research
Caitlin W Hicks, Joseph K Canner, Kevin Kirkland, Mahmoud B Malas, James H Black, Christopher J Abularrage
BACKGROUND: Hemodialysis (HD) has been shown to be an independent predictor of poor outcomes after femoropopliteal revascularization procedures in patients with chronic limb-threatening ischemia. However, HD patients tend to have isolated infrageniculate disease, an anatomic risk factor for inferior patency. We aimed to compare outcomes for HD versus non-HD patients after infrageniculate open lower extremity bypass (LEB) and endovascular peripheral vascular interventions (PVIs). METHODS: Data from the Society for Vascular Surgery Vascular Quality Initiative database (2008-2014) were analyzed...
June 2018: Journal of Surgical Research
Tobias Haltmeier, Kenji Inaba, Beat Schnüriger, Stefano Siboni, Elizabeth Benjamin, Lydia Lam, Damon Clark, Demetrios Demetriades
BACKGROUND: Major trauma leads to increased nutritional requirements. However, little is known about the actual amount of calories and protein administered and the factors affecting the intake over time in critically ill trauma patients. METHODS: Prospective study including 100 trauma patients admitted to the Los Angeles County + University of Southern California Medical Center intensive care unit between March 2014 and October 2014. Inclusion criteria were age > 16 y, surgery at admission, and no oral nutrition...
June 2018: Journal of Surgical Research
Ze-Wu Meng, Xiu-Quan Lin, Jin-Hai Zhu, Sheng-Hua Han, Yan-Ling Chen
BACKGROUND: In this study, we developed and validated a nomogram to predict lymph node metastasis before surgery in patients with intrahepatic cholangiocarcinoma (ICC). METHODS: Using the data from January 2006 to January 2015, we enrolled a total of 218 eligible patients with clinicopathologically confirmed ICC as a primary cohort to develop the nomogram. After various variables before surgery were analyzed by multivariable logistic regression, we combined the preoperative carbohydrate antigen 19-9, primary site of tumor, lymphonodus size on computed tomography imaging, tumor growth pattern, and (if applicable) histologic grade to make two different predictive nomograms...
June 2018: Journal of Surgical Research
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