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Journal of Surgical Research

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https://www.readbyqxmd.com/read/28890131/characterization-of-systemic-neutrophil-function-in-patients-undergoing-colorectal-cancer-resection
#1
Jonathan J R Richardson, Charles Hendrickse, Fang Gao-Smith, David R Thickett
BACKGROUND: In patients with colorectal cancer, the generation and maintenance of a systemic inflammatory response is associated with poor outcomes. Neutrophils have been implicated in the prognosis of such patients, but little is known about their functional response to surgery. This study was conducted to characterize neutrophil function of patients undergoing colorectal cancer resection. MATERIALS AND METHODS: Systemic neutrophils were isolated from patients with colorectal cancer who underwent surgical resection preoperatively (day 0) and postoperatively (day 1 and day 3)...
September 7, 2017: Journal of Surgical Research
https://www.readbyqxmd.com/read/28844460/barriers-to-the-implementation-and-uptake-of-simulation-based-training-programs-in-general-surgery-a-multinational-qualitative-study
#2
Shady G Hosny, Maximilian J Johnston, Philip H Pucher, Simon Erridge, Ara Darzi
BACKGROUND: Despite evidence demonstrating the advantages of simulation training in general surgery, it is not widely integrated into surgical training programs worldwide. The aim of this study was to identify barriers and facilitators to the implementation and uptake of surgical simulation training programs. METHODS: A multinational qualitative study was conducted using semi-structured interviews of general surgical residents and experts. Each interview was audio recorded, transcribed verbatim, and underwent emergent theme analysis...
August 24, 2017: Journal of Surgical Research
https://www.readbyqxmd.com/read/28807327/problems-of-artificial-neural-network
#3
LETTER
Sadettin Er, Mesut Tez
No abstract text is available yet for this article.
August 11, 2017: Journal of Surgical Research
https://www.readbyqxmd.com/read/28732685/the-three-paradigm-shifts-of-the-1980s-and-the-aas
#4
Michael Zinner
No abstract text is available yet for this article.
July 18, 2017: Journal of Surgical Research
https://www.readbyqxmd.com/read/28711371/extubation-to-high-flow-nasal-cannula-in-critically-ill-surgical-patients
#5
Navpreet K Dhillon, Eric J T Smith, Ara Ko, Megan Y Harada, Danielle Polevoi, Richard Liang, Galinos Barmparas, Eric J Ley
BACKGROUND: High-flow nasal cannula (HFNC) is increasingly used to reduce reintubations in patients with respiratory failure. Benefits include providing positive end expiratory pressure, reducing anatomical dead space, and decreasing work of breathing. We sought to compare outcomes of critically ill surgical patients extubated to HFNC versus conventional therapy. METHODS: A retrospective review was conducted in the surgical intensive care unit of an academic center during August 2015 to February 2016...
July 12, 2017: Journal of Surgical Research
https://www.readbyqxmd.com/read/28711369/predicting-failure-to-rescue-after-abdominal-aortic-aneurysm-repair-in-elderly-patients
#6
Caitlin W Hicks, Anna O'Kelly, Tammam Obeid, Satinderjit Locham, Mahmoud B Malas
BACKGROUND: We aim to describe trends in failure to rescue (FTR) among elderly patients undergoing elective open aortic aneurysm repair (OAR) and endovascular aortic aneurysm repair (EVAR). MATERIALS AND METHODS: All patients aged ≥80 y recorded in the Vascular Quality Initiative database (2002-2014) undergoing nonruptured infrarenal AAA repair were included. Primary outcome was FTR, defined as percentage of deaths in patients who had a complication within 30 d of surgery...
July 12, 2017: Journal of Surgical Research
https://www.readbyqxmd.com/read/28711368/the-safety-and-feasibility-of-early-discharge-following-ileostomy-reversal-a-national-surgical-quality-improvement-program-analysis
#7
Arash Azin, Emily Le Souder, David Urbach, Allan Okrainec, Sami A Chadi, Fayez Quereshy, Timothy D Jackson, Ahmad Elnahas
BACKGROUND: This study aimed to compare 30-day clinical outcomes following routine ileostomy reversal between patients that underwent early discharge (<24 h) and standard discharge (postoperative day [POD] 2 or 3). METHODS: A retrospective cohort analysis was conducted between 2005 and 2014 using the American College of Surgeons National Surgical Quality Improvement Program data set. All patients undergoing ileostomy reversal who were discharged on POD 0 or 1 (early discharge group [EDG]) versus POD 2 or 3 (standard discharge group [SDG]) were identified...
July 12, 2017: Journal of Surgical Research
https://www.readbyqxmd.com/read/28711367/optimization-of-a-multigene-biochip-for-detection-of-relapsed-and-early-relapsed-colorectal-cancer
#8
Yu-Tang Chang, Yung-Sung Yeh, Cheng-Jen Ma, Ching-Wen Huang, Hsiang-Lin Tsai, Ming-Yii Huang, Tian-Lu Cheng, Jaw-Yuan Wang
BACKGROUND: With the recent development of molecular markers, strategies for identifying patients with colorectal cancer (CRC) having a high risk of postoperative early relapse (within 1 y) and relapse have been improved. We previously constructed a multigene biochip with 19 candidate genes. The objective of the present study was to optimize a multigene biochip for detecting the risk of postoperative early relapse and relapse in patients with CRC. METHODS: We included 357 patients with stage I-III CRC who underwent curative resection at a single institution between June 2010 and May 2015...
July 12, 2017: Journal of Surgical Research
https://www.readbyqxmd.com/read/28684110/the-association-for-academic-surgeons-2001-2010-a-decade-of-inclusiveness
#9
Daniel I Chu, Herbert Chen
The Association for Academic Surgery (AAS) was established to inspire and develop academic surgeons. Since its founding in 1966, each decade has been marked by continued growth and innovations. The era of 2001-2010 was a decade notable for its focus on inclusiveness and diversity. In those ten years, the AAS grew its membership from all surgical backgrounds, established defining programs that remain today, and invested substantially in international outreach. In this article, we review these historical highlights and will demonstrate that the AAS remains the most important home for the young academic surgeon...
July 3, 2017: Journal of Surgical Research
https://www.readbyqxmd.com/read/28676224/pediatric-non-fatal-drowning-events-do-they-warrant-trauma-team-activation
#10
LETTER
Jonathon Webber, Andrew C Schmidt, Justin R Sempsrott, David Szpilman, Ana Catarina Queiroga
No abstract text is available yet for this article.
July 1, 2017: Journal of Surgical Research
https://www.readbyqxmd.com/read/28666527/pediatric-near-drowning-events-do-they-warrant-trauma-team-activation
#11
LETTER
Pranit N Chotai, Lisa Manning, Benjamin Eithun, Joshua C Ross, James W Eubanks, Chad Hamner, Ankush Gosain
No abstract text is available yet for this article.
June 27, 2017: Journal of Surgical Research
https://www.readbyqxmd.com/read/28918962/the-1990s-and-the-association-for-academic-surgery
#12
David I Soybel
This lecture reviews the progress of the Association for Academic Surgery during the 1990s, a decade of sweeping innovations in technology, communication, and biomedical sciences; a well as a decade of transition in the demographics of surgical trainees; and a decade of new and previously unimagined possibilities for new directions in academic surgical careers.
September 2017: Journal of Surgical Research
https://www.readbyqxmd.com/read/28918961/remembrances-from-an-early-follower-and-leader-of-the-association-for-academic-surgery
#13
Hiram C Polk
This reflection retraces the evolution of early followers and leaders. Social change and early contributions set the stage for the current Association for Academic Surgery. Perhaps the most important contribution was Dr. George Zuidema's theme of inclusiveness. AAS was a decade ahead of its time in that regard.
September 2017: Journal of Surgical Research
https://www.readbyqxmd.com/read/28918960/erratum
#14
(no author information available yet)
No abstract text is available yet for this article.
September 2017: Journal of Surgical Research
https://www.readbyqxmd.com/read/28918959/the-association-for-academic-surgery-its-first-decade
#15
George D Zuidema
No abstract text is available yet for this article.
September 2017: Journal of Surgical Research
https://www.readbyqxmd.com/read/28918958/the-association-for-academic-surgery-2011-present-standing-on-the-shoulders-of-giants
#16
Allison L Speer, Lillian S Kao
The Association for Academic Surgery (AAS), which is a society dedicated to inspiring and developing young academic surgeons, recently celebrated its 50th anniversary. Each decade since its inception has seen incredible growth. This most recent decade, from 2011 to present, has been characterized by: (1) reevaluation and clarification of the society's vision, mission, core values and organizational structure; (2) diversification of the membership and leadership; (3) support for international outreach and global surgery research; (4) expansion of its impact through social media; and (5) adaptability to a changing political climate...
September 2017: Journal of Surgical Research
https://www.readbyqxmd.com/read/28918957/introduction-to-the-2017-founders-lecture-of-the-association-for-academic-surgery
#17
Francis Charles Brunicardi, Mitra Jamshidian
This year's Founders' Lecture will focus on the founding and history of the Association for Academic Surgery (AAS), as presented by five past presidents. The lecture will give the readers a unique and condensed perspective on the remarkable history of the AAS. The AAS was founded in 1967 by Dr George Zuidema with the mission to offer young academic surgeons an inclusive forum for discussion about surgical research and the opportunity for professional growth.1 Since its establishment in 1966, with a membership of only 33 people,1the organization has grown into a diverse international organization with over 2800 members...
September 2017: Journal of Surgical Research
https://www.readbyqxmd.com/read/28711370/assessing-the-risk-of-hypercalcemic-crisis-in-patients-with-primary-hyperparathyroidism
#18
Andrew J Lowell, Norah M Bushman, Xing Wang, Yue Ma, Susan C Pitt, Rebecca S Sippel, David F Schneider, Reese W Randle
BACKGROUND: Hypercalcemic crisis (HC) is a potentially life-threatening manifestation of primary hyperparathyroidism (PHPT). This study aimed to identify patients with PHPT at greatest risk for developing HC. METHODS: This retrospective cohort study included patients with a preoperative calcium of at least 12 mg/dL undergoing initial parathyroidectomy for PHPT from 11/2000 to 03/2016. We compared those with HC, defined as needing hospitalization for hypercalcemia, to those without HC...
September 2017: Journal of Surgical Research
https://www.readbyqxmd.com/read/28587892/the-modified-frailty-index-to-predict-morbidity-and-mortality-for-retroperitoneal-sarcoma-resections
#19
Jiwon Sarah Park, Sarah B Bateni, Richard J Bold, Amanda R Kirane, Daniel J Canter, Robert J Canter
BACKGROUND: The modified frailty index (mFI) is an important method to risk-stratify surgical patients and has been validated for general surgery and selected surgical subspecialties. However, there are currently no data assessing the efficacy of the mFI to predict acute morbidity and mortality in patients undergoing surgery for retroperitoneal sarcoma. METHODS: Using the American College of Surgeons' National Surgical Quality Improvement Program from 2007 to 2012, we performed a retrospective analysis of patients with a diagnosis of primary malignant retroperitoneal neoplasm who underwent surgical resection...
September 2017: Journal of Surgical Research
https://www.readbyqxmd.com/read/28583756/thrombelastography-indicates-limitations-of-animal-models-of-trauma-induced-coagulopathy
#20
Gregory R Stettler, Ernest E Moore, Hunter B Moore, Peter J Lawson, Miguel Fragoso, Geoffrey R Nunns, Christopher C Silliman, Anirban Banerjee
BACKGROUND: Thrombelastography (TEG) has been used to characterize the coagulation changes associated with injury and shock. Animal models developed to investigate trauma-induced coagulopathy (TIC) have failed to produce excessive bleeding. We hypothesize that a native TEG will demonstrate marked differences in humans compared with these experimental models, which explains the difficulties in reproducing a clinically relevant coagulopathy in animal models. METHODS: Whole blood was collected from 138 healthy human volunteers, 25 swine and 66 Sprague-Dawley rats before experimentation...
September 2017: Journal of Surgical Research
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