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Journal of Surgical Research

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https://www.readbyqxmd.com/read/28318527/the-ideal-porcine-model-for-major-liver-resection-is-there-any-yet
#1
LETTER
Mohamed Bekheit, Petru Bucur, Eric Vibert
No abstract text is available yet for this article.
March 7, 2017: Journal of Surgical Research
https://www.readbyqxmd.com/read/28117092/then-we-all-fall-down-fall-mortality-by-trauma-center-level
#2
Daniel Roubik, Alan D Cook, Jeanette G Ward, Kristina M Chapple, Sheldon Teperman, Melvin E Stone, Brian Gross, Forrest O Moore
BACKGROUND: Ground-level falls (GLFs) are the predominant mechanism of injury in US trauma centers and accompany a spectrum of comorbidities, injury severity, and physiologic derangement. Trauma center levels define tiers of capability to treat injured patients. We hypothesized that risk-adjusted observed-to-expected mortality (O:E) by trauma center level would evaluate the degree to which need for care was met by provision of care. MATERIALS AND METHODS: This retrospective cohort study used National Trauma Data Bank files for 2007-2014...
January 6, 2017: Journal of Surgical Research
https://www.readbyqxmd.com/read/28095987/an-anatomic-risk-model-to-screen-post-endovascular-aneurysm-repair-patients-for-aneurysm-sac-enlargement
#3
Chien Yi M Png, Rami O Tadros, William E Beckerman, Daniel K Han, Melissa L Tardiff, Marielle R Torres, Michael L Marin, Peter L Faries
BACKGROUND: Follow-up computed tomography angiography (CTA) scans add considerable postimplantation costs to endovascular aneurysm repairs (EVARs) of abdominal aortic aneurysms (AAAs). By building a risk model, we hope to identify patients at low risk for aneurysm sac enlargement to minimize unnecessary CTAs. METHODS: 895 consecutive patients who underwent EVAR for AAA were reviewed, of which 556 met inclusion criteria. A Probit model was created for aneurysm sac enlargement, with preoperative aneurysm morphology, patient demographics, and operative details as variables...
December 27, 2016: Journal of Surgical Research
https://www.readbyqxmd.com/read/28032577/evaluation-of-neutrophil-to-lymphocyte-ratio-as-a-potential-biomarker-for-acute-cholecystitis
#4
Andrei M Beliaev, Neville Angelo, Michael Booth, Colleen Bergin
BACKGROUND: The diagnosis of acute cholecystitis (AC) is frequently associated with an increase in white cell count (WCC) and C-reactive protein (CRP). However, one or both of these inflammatory biomarkers can be normal in AC. The aim of this study was to evaluate and compare the discriminative powers of the neutrophil-to-lymphocyte ratio (NLR) with WCC and CRP in diagnosing AC. METHODS: This was a retrospective cohort study. For more than a period of 5 y, 1959 patients were identified from the cholecystectomy Registry...
March 2017: Journal of Surgical Research
https://www.readbyqxmd.com/read/28032576/informing-the-process-of-consent-for-surgery-identification-of-key-constructs-and-quality-factors
#5
N Mark Bagnall, Philip H Pucher, Maximilian J Johnston, Sonal Arora, Thanos Athanasiou, Omar Faiz, Lord Ara Darzi
BACKGROUND: Informed consent is a fundamental requirement of any invasive procedure. Failure to obtain appropriate and informed consent may result in unwanted or unnecessary procedures, as well as financial penalty in case of litigation. The aim of this study was to identify key constructs of the consent process which might be used to determine the performance of clinicians taking informed consent in surgery. METHODS: A multimodal methodology was used. A systematic review was conducted in accordance with PRISMA guidelines to identify evidence-based components of the consent process...
March 2017: Journal of Surgical Research
https://www.readbyqxmd.com/read/28032575/liver-resection-versus-liver-resection-plus-tace-for-patients-with-hepatocellular-carcinoma-beyond-milan-criteria
#6
Chuan Li, Tian-Fu Wen, Lv-Nan Yan, Wu-Sheng Lu, Bo Li, Wen-Tao Wang, Ming-Qing Xu, Jia-Yin Yang
BACKGROUND: The recurrence of patients with hepatocellular carcinoma (HCC) beyond the Milan criteria after liver resection (LR) is common. This study aimed to clarify whether LR plus postoperative adjuvant transcatheter arterial chemoembolization (TACE) could improve the outcomes of patients with HCC beyond the Milan criteria after LR. METHODS: A total of 754 consecutive patients with HCC beyond the Milan criteria who received LR alone (n = 459) or LR + TACE (n = 295) were included...
March 2017: Journal of Surgical Research
https://www.readbyqxmd.com/read/28032574/a-novel-technique-of-inserting-pancreaticogastrostomy-with-duct-to-mucosa-anastomosis-can-potentially-reduce-postoperative-pancreatic-fistula
#7
Cai-de Lu, Jing Huang, Yong-Fei Hua, Ammar Asrar Javed, Jin He, Sheng-Dong Wu, Wei-Ming Yu, Chang-Jiang Lu
BACKGROUND: We describe our novel technique of inserting pancreaticogastrostomy (IPG) after pancreaticoduodenectomy. In our technique, the seromuscular and mucosal layers of the posterior gastric wall are separated to create a mucosal pouch. A duct-to-mucosa anastomosis is performed through a small incision in the mucosal layer. An inner suture at the seromuscular-mucosal margin incorporating the pancreatic parenchyma and an outer suture on the exterior margin of the seromuscular layer to wrap the pouch around the pancreas are placed to complete the IPG...
March 2017: Journal of Surgical Research
https://www.readbyqxmd.com/read/28032572/postoperative-sepsis-prediction-in-patients-undergoing-major-cancer-surgery
#8
Akshay Sood, Firas Abdollah, Jesse D Sammon, Nivedita Arora, Matthew Weeks, James O Peabody, Mani Menon, Quoc-Dien Trinh
BACKGROUND: Cancer patients are at increased risk for postoperative sepsis. However, studies addressing the issue are lacking. We sought to identify preoperative and intraoperative predictors of 30-d sepsis after major cancer surgery (MCS) and derive a postoperative sepsis risk stratification tool. METHODS: Patients undergoing one of nine MCSs (gastrointestinal, urological, gynecologic, or pulmonary) were identified within the American College of Surgeons National Surgical Quality Improvement Program (2005-2011, n = 69,169)...
March 2017: Journal of Surgical Research
https://www.readbyqxmd.com/read/28032571/readmissions-after-general-surgery-a-prospective-multicenter-audit
#9
Matthew J Lee, Sarah L Daniels, Jonathan R L Wild, Timothy R Wilson
BACKGROUND: Readmission rates after surgical procedures are viewed as a marker of quality of care and as a driver to improve outcomes in the United Kingdom, they are not remunerated. However, readmissions are not wholly avoidable. The aim of this study was to develop a regional overview of readmissions to determine the proportion that might be avoidable and to examine predictors of readmissions at a unit level. METHODS: We undertook a prospective multicenter audit of readmissions following National Health Service funded general surgical procedures in five National Health Service hospitals and three independent sector providers over a 2-wk period...
March 2017: Journal of Surgical Research
https://www.readbyqxmd.com/read/28032570/hypokalemia-during-acute-metabolic-acidosis-on-hemodilution-with-succinylated-gelatin-in-rats
#10
Johanna K Teloh, Ricarda Rohrig, Indra N Waack, Herbert de Groot
BACKGROUND: Extracellular metabolic acidosis of mineral origin is commonly associated with plasma hyperkalemia. Nevertheless, in previous experiments, animals subjected to acute metabolic acidosis induced by normovolemic hemodilution using a colloidal volume replacement solution containing succinylated gelatin (gelafundin), developed a hypokalemic state with concomitant marked increases in diuresis and renal potassium excretion. In the present study, the succinylated gelatin's impact on diuresis and consequently potassium excretion was studied...
March 2017: Journal of Surgical Research
https://www.readbyqxmd.com/read/28032569/value-of-the-prognostic-nutritional-index-in-advanced-gastric-cancer-treated-with-preoperative-chemotherapy
#11
Jianyi Sun, Donghai Wang, Ying Mei, Hailong Jin, Kankai Zhu, Xiaosun Liu, Qing Zhang, Jiren Yu
BACKGROUND: The prognostic nutritional index (PNI) is a useful parameter indicating the immune and nutritional status of cancer patients; this study investigated the prognostic value of the PNI in advanced gastric cancer patients treated with preoperative chemotherapy. MATERIALS AND METHODS: We retrospectively reviewed 117 advanced gastric cancer patients who met the inclusion criteria for preoperative chemotherapy and underwent surgical resection from July 2004 to December 2011...
March 2017: Journal of Surgical Research
https://www.readbyqxmd.com/read/28032568/seven-day-intensive-preoperative-rehabilitation-for-elderly-patients-with-lung-cancer-a-randomized-controlled-trial
#12
Yutian Lai, Jian Huang, Mei Yang, Jianhua Su, Jing Liu, Guowei Che
BACKGROUND: As a newly developed treatment, preoperative pulmonary rehabilitation (PR) has been studied in depth. However, few studies have assessed the relationship between advanced age and a shorter term intensive pattern of preoperative PR in patients with lung cancer (LC) and especially those patients waiting for therapeutic LC surgeries. This study investigated short-term preoperative PR combined with inspiratory muscle training (IMT) and aerobic endurance training in elderly patients scheduled to undergo LC lobectomy...
March 2017: Journal of Surgical Research
https://www.readbyqxmd.com/read/28032563/surgeon-not-technique-defines-outcomes-after-central-venous-port-insertion
#13
Audrey E Ertel, Zachary D McHenry, Vijay K Venkatesan, Dennis J Hanseman, Koffi Wima, Richard S Hoehn, Shimul A Shah, Daniel E Abbott
BACKGROUND: Although central venous access for port placement is common and relatively safe, complications and poor resource utilization occur. We hypothesized that despite the simplicity of port placement, surgeon and/or resident performance-rather than technique-is associated with clinical outcomes and operating room efficiency. MATERIALS AND METHODS: Medical records of 1200 patients who underwent port placement between 2012 and 2015 at our institution were retrospectively reviewed...
March 2017: Journal of Surgical Research
https://www.readbyqxmd.com/read/28032562/a-novel-secure-transfixing-blood-vessel-occluder-comparison-with-the-hemoclip-in-the-porcine-model
#14
Arnold Miller, Nir Lilach, Ana-Maria Botero-Anug, Udi Willenz, Raanan Miller
BACKGROUND: Secure vessel occlusion is critical to the success of all surgical and interventional procedures. The purpose of this study was to compare in vivo the use of the Amsel Vessel Occluder (AVO), a novel occlusion clip device for secure blood vessel closure, with one of the many commercially available hemoclips, the Ligaclip, in the porcine model. METHODS: Vessel closure of arteries and veins was performed on 10 swine to compare the ease of use, safety, and efficacy of the AVO with the Ligaclip as well as the tissue response at 7 and 30 d...
March 2017: Journal of Surgical Research
https://www.readbyqxmd.com/read/28032558/early-learners-as-health-coaches-for-older-adults-preparing-for-surgery
#15
Jennifer A Kaplan, Zabecca Brinson, Rebecca Hofer, Patricia O'Sullivan, Anna Chang, Helen Horvath, George J Chang, Emily Finlayson
BACKGROUND: Few opportunities exist for early learners to engage in authentic roles on health care teams. In a geriatric optimization clinic for frail high-risk surgical patients, first-year medical and nurse practitioner students were integrated into an interprofessional team as health coaches. MATERIALS AND METHODS: Frail surgical patients with planned operations were referred to a new preoperative optimization clinic to see a geriatrician, occupational, and physical therapists and a nutritionist...
March 2017: Journal of Surgical Research
https://www.readbyqxmd.com/read/28032554/detection-of-clinically-important-colorectal-surgical-site-infection-using-bayesian-network
#16
Sunghwan Sohn, David W Larson, Elizabeth B Habermann, James M Naessens, Jasim Y Alabbad, Hongfang Liu
BACKGROUND: Despite extensive efforts to monitor and prevent surgical site infections (SSIs), real-time surveillance of clinical practice has been sparse and expensive or nonexistent. However, natural language processing (NLP) and machine learning (i.e., Bayesian network analysis) may provide the methodology necessary to approach this issue in a new way. We investigated the ability to identify SSIs after colorectal surgery (CRS) through an automated detection system using a Bayesian network...
March 2017: Journal of Surgical Research
https://www.readbyqxmd.com/read/27993221/exendin-4-a-glucagon-like-peptide-1-analogue-accelerates-diabetic-wound-healing
#17
Jun-Neng Roan, Han-Ni Cheng, Chao-Chung Young, Chi-Ju Lee, Ming-Long Yeh, Chwan-Yau Luo, Yau-Sheng Tsai, Chen-Fuh Lam
BACKGROUND: Diabetes disregulates inflammatory responses and impairs vascular function in wounds. Glucagon-like peptide-1 receptor (Glp-1R) agonists are hypoglycemic agents with pleiotropic vascular protective and anti-inflammatory effects. The therapeutic potential of a Glp-1 analogue in a diabetic rat model of excisional wound injury was investigated. MATERIALS AND METHODS: Excisional wounds were created on the dorsum of streptozotocin-induced diabetic rats, which received placebo or Glp-1 analogue exendin-4 (Ex4; 0...
February 2017: Journal of Surgical Research
https://www.readbyqxmd.com/read/27993220/intestinal-alkaline-phosphatase-decreases-intraperitoneal-adhesion-formation
#18
Sanjiv K Hyoju, Sara Morrison, Sarah Gul, Mohammad Hadi Gharedaghi, Mohamed Mussa, Mehran Najibi, Konstantinos P Economopoulos, Sulaiman R Hamarneh, Richard A Hodin
BACKGROUND: Damage to the peritoneum initiates an inflammatory response leading to the formation of adhesions, which subsequently cause significant morbidity in some patients. Intestinal alkaline phosphatase (IAP) is a gut enzyme capable of detoxifying various inflammatory mediators such as lipopolysaccharide, lipoteichoic acid, CpG DNA, and adenosine triphosphate. In this study, we aimed to examine the anti-inflammatory effects of IAP on postoperative adhesions in mice. METHODS: C57BL/6 mice were subjected to a midline laparotomy and then six musculoperitoneal buttons (MPBs) were created by pinching and ligating the peritoneum and underlying muscle...
February 2017: Journal of Surgical Research
https://www.readbyqxmd.com/read/27993219/behavior-of-a-new-long-chain-cyanoacrylate-tissue-adhesive-used-for-mesh-fixation-in-hernia-repair
#19
Juan M Bellón, Mar Fernández-Gutiérrez, Marta Rodríguez, Paloma Pérez-López, Bárbara Pérez-Köhler, Andree Kühnhardt, Gemma Pascual, Julio San Román
BACKGROUND: Synthetic tissue adhesives (TA) are sometimes used in hernia repair surgery. This study compares the use of a new, noncommercial, long-chain cyanoacrylate (n-octyl) TA and Ifabond for mesh fixation. MATERIALS AND METHODS: In two implant models in the rabbit, expanded polytetrafluorethylene meshes were fixed to the parietal peritoneum using a TA or tacks (intraperitoneal model), or polypropylene meshes used to repair partial abdominal wall defects were fixed with a TA or sutures (extraperitoneal model)...
February 2017: Journal of Surgical Research
https://www.readbyqxmd.com/read/27993218/magnetic-compression-anastomosis-for-enteroenterostomy-under-peritonitis-conditions-in-dogs
#20
Hongke Zhang, Kai Tan, Chao Fan, Jingwei Du, Jiangbin Li, Tao Yang, Yi Lv, Xilin Du
BACKGROUND: The risk of complications and mortality are high after enteroenterostomy in severe peritonitic conditions. Magnetic compression anastomosis (MCA) is a sutureless technique of high efficacy and safety. The purpose of this study was to compare the efficacy of MCA for enteroenterostomy with stapled and hand-sewn techniques under peritonitic conditions. METHODS: The peritonitic conditions were created by puncturing the colon with a circular blade in 27 mongrel dogs...
February 2017: Journal of Surgical Research
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