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Journal of Surgical Research

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https://www.readbyqxmd.com/read/28711371/extubation-to-high-flow-nasal-cannula-in-critically-ill-surgical-patients
#1
Navpreet K Dhillon, Eric J T Smith, Ara Ko, Megan Y Harada, Danielle Polevoi, Richard Liang, Galinos Barmparas, Eric J Ley
BACKGROUND: High-flow nasal cannula (HFNC) is increasingly used to reduce reintubations in patients with respiratory failure. Benefits include providing positive end expiratory pressure, reducing anatomical dead space, and decreasing work of breathing. We sought to compare outcomes of critically ill surgical patients extubated to HFNC versus conventional therapy. METHODS: A retrospective review was conducted in the surgical intensive care unit of an academic center during August 2015 to February 2016...
July 12, 2017: Journal of Surgical Research
https://www.readbyqxmd.com/read/28711370/assessing-the-risk-of-hypercalcemic-crisis-in-patients-with-primary-hyperparathyroidism
#2
Andrew J Lowell, Norah M Bushman, Xing Wang, Yue Ma, Susan C Pitt, Rebecca S Sippel, David F Schneider, Reese W Randle
BACKGROUND: Hypercalcemic crisis (HC) is a potentially life-threatening manifestation of primary hyperparathyroidism (PHPT). This study aimed to identify patients with PHPT at greatest risk for developing HC. METHODS: This retrospective cohort study included patients with a preoperative calcium of at least 12 mg/dL undergoing initial parathyroidectomy for PHPT from 11/2000 to 03/2016. We compared those with HC, defined as needing hospitalization for hypercalcemia, to those without HC...
July 12, 2017: Journal of Surgical Research
https://www.readbyqxmd.com/read/28711369/predicting-failure-to-rescue-after-abdominal-aortic-aneurysm-repair-in-elderly-patients
#3
Caitlin W Hicks, Anna O'Kelly, Tammam Obeid, Satinderjit Locham, Mahmoud B Malas
BACKGROUND: We aim to describe trends in failure to rescue (FTR) among elderly patients undergoing elective open aortic aneurysm repair (OAR) and endovascular aortic aneurysm repair (EVAR). MATERIALS AND METHODS: All patients aged ≥80 y recorded in the Vascular Quality Initiative database (2002-2014) undergoing nonruptured infrarenal AAA repair were included. Primary outcome was FTR, defined as percentage of deaths in patients who had a complication within 30 d of surgery...
July 12, 2017: Journal of Surgical Research
https://www.readbyqxmd.com/read/28711368/the-safety-and-feasibility-of-early-discharge-following-ileostomy-reversal-a-national-surgical-quality-improvement-program-analysis
#4
Arash Azin, Emily Le Souder, David Urbach, Allan Okrainec, Sami A Chadi, Fayez Quereshy, Timothy D Jackson, Ahmad Elnahas
BACKGROUND: This study aimed to compare 30-day clinical outcomes following routine ileostomy reversal between patients that underwent early discharge (<24 h) and standard discharge (postoperative day [POD] 2 or 3). METHODS: A retrospective cohort analysis was conducted between 2005 and 2014 using the American College of Surgeons National Surgical Quality Improvement Program data set. All patients undergoing ileostomy reversal who were discharged on POD 0 or 1 (early discharge group [EDG]) versus POD 2 or 3 (standard discharge group [SDG]) were identified...
July 12, 2017: Journal of Surgical Research
https://www.readbyqxmd.com/read/28711367/optimization-of-a-multigene-biochip-for-detection-of-relapsed-and-early-relapsed-colorectal-cancer
#5
Yu-Tang Chang, Yung-Sung Yeh, Cheng-Jen Ma, Ching-Wen Huang, Hsiang-Lin Tsai, Ming-Yii Huang, Tian-Lu Cheng, Jaw-Yuan Wang
BACKGROUND: With the recent development of molecular markers, strategies for identifying patients with colorectal cancer (CRC) having a high risk of postoperative early relapse (within 1 y) and relapse have been improved. We previously constructed a multigene biochip with 19 candidate genes. The objective of the present study was to optimize a multigene biochip for detecting the risk of postoperative early relapse and relapse in patients with CRC. METHODS: We included 357 patients with stage I-III CRC who underwent curative resection at a single institution between June 2010 and May 2015...
July 12, 2017: Journal of Surgical Research
https://www.readbyqxmd.com/read/28684110/the-association-for-academic-surgeons-2001-2010-a-decade-of-inclusiveness
#6
Daniel I Chu, Herbert Chen
The Association for Academic Surgery (AAS) was established to inspire and develop academic surgeons. Since its founding in 1966, each decade has been marked by continued growth and innovations. The era of 2001-2010 was a decade notable for its focus on inclusiveness and diversity. In those ten years, the AAS grew its membership from all surgical backgrounds, established defining programs that remain today, and invested substantially in international outreach. In this article, we review these historical highlights and will demonstrate that the AAS remains the most important home for the young academic surgeon...
July 3, 2017: Journal of Surgical Research
https://www.readbyqxmd.com/read/28676224/pediatric-non-fatal-drowning-events-do-they-warrant-trauma-team-activation
#7
LETTER
Jonathon Webber, Andrew C Schmidt, Justin R Sempsrott, David Szpilman, Ana Catarina Queiroga
No abstract text is available yet for this article.
July 1, 2017: Journal of Surgical Research
https://www.readbyqxmd.com/read/28666527/pediatric-near-drowning-events-do-they-warrant-trauma-team-activation
#8
LETTER
Pranit N Chotai, Lisa Manning, Benjamin Eithun, Joshua C Ross, James W Eubanks, Chad Hamner, Ankush Gosain
No abstract text is available yet for this article.
June 27, 2017: Journal of Surgical Research
https://www.readbyqxmd.com/read/28602225/erratum
#9
(no author information available yet)
No abstract text is available yet for this article.
June 8, 2017: Journal of Surgical Research
https://www.readbyqxmd.com/read/28595817/relationships-between-study-habits-burnout-and-general-surgery-resident-performance-on-the-american-board-of-surgery-in-training-examination
#10
Matthew R Smeds, Carol R Thrush, Faith K McDaniel, Roop Gill, Mary K Kimbrough, Brian D Shames, Jeffrey J Sussman, Joseph M Galante, Catherine M Wittgen, Parswa Ansari, Steven R Allen, Michael S Nussbaum, Donald T Hess, David C Knight, Frederick R Bentley
BACKGROUND: The American Board of Surgery In-Training Examination (ABSITE) is used by programs to evaluate the knowledge and readiness of trainees to sit for the general surgery qualifying examination. It is often used as a tool for resident promotion and may be used by fellowship programs to evaluate candidates. Burnout has been associated with job performance and satisfaction; however, its presence and effects on surgical trainees' performance are not well studied. We sought to understand factors including burnout and study habits that may contribute to performance on the ABSITE examination...
May 12, 2017: Journal of Surgical Research
https://www.readbyqxmd.com/read/28602224/general-surgeon-management-of-complex-hepatopancreatobiliary-trauma-at-a-level-i-trauma-center
#11
Peter Kilen, Alissa Greenbaum, Richard Miskimins, Manuel Rojo, Razvan Preda, Thomas Howdieshell, Stephen Lu, Sonlee West
BACKGROUND: The impact of general surgeons (GS) taking trauma call on patient outcomes has been debated. Complex hepatopancreatobiliary (HPB) injuries present a particular challenge and often require specialized care. We predicted no difference in the initial management or outcomes of complex HPB trauma between GS and trauma/critical care (TCC) specialists. MATERIALS AND METHODS: A retrospective review of patients who underwent operative intervention for complex HPB trauma from 2008 to 2015 at an ACS-verified level I trauma center was performed...
May 11, 2017: Journal of Surgical Research
https://www.readbyqxmd.com/read/28602222/diabetes-and-hyperglycemia-as-risk-factors-for-postoperative-outcome-in-maxillofacial-surgery
#12
Roman K Rahimi-Nedjat, Keyvan Sagheb, Andreas Pabst, Moritz Foersch, Collin Jacobs, Leonie Vollandt, Bilal Al-Nawas, Christian Walter
BACKGROUND: Aim of this study was to investigate the frequency of complications in maxillofacial surgery in-patients in correlation to diabetes mellitus or a pathologically altered glucose metabolism. MATERIALS AND METHODS: All patients' electronic health records were analyzed retrospectively. Diabetes mellitus anamnesis, the treatment regime, blood glucose levels, and the duration of inpatient treatment were recorded. Glucose readings ≥200 mg/dL measured at any time and fasting glucose levels of ≥110 mg/dL were defined as hyperglycemic...
May 11, 2017: Journal of Surgical Research
https://www.readbyqxmd.com/read/28602221/violent-reinjury-risk-assessment-instrument-vrrai-for-hospital-based-violence-intervention-programs
#13
Erik J Kramer, James Dodington, Ava Hunt, Terrell Henderson, Adaobi Nwabuo, Rochelle Dicker, Catherine Juillard
BACKGROUND: Violent injury is the second most common cause of death among 15- to 24-year olds in the US. Up to 58% of violently injured youth return to the hospital with a second violent injury. Hospital-based violence intervention programs (HVIPs) have been shown to reduce injury recidivism through intensive case management. However, no validated guidelines for risk assessment strategies in the HVIP setting have been reported. We aimed to use qualitative methods to investigate the key components of risk assessments employed by HVIP case managers and to propose a risk assessment model based on this qualitative analysis...
May 11, 2017: Journal of Surgical Research
https://www.readbyqxmd.com/read/28602220/inhibition-of-microrna-24-increases-liver-fibrosis-by-enhanced-menin-expression-in-mdr2-mice
#14
Chad Hall, Laurent Ehrlich, Fanyin Meng, Pietro Invernizzi, Francesca Bernuzzi, Terry C Lairmore, Gianfranco Alpini, Shannon Glaser
BACKGROUND: Liver transplantation remains the primary treatment for primary sclerosing cholangitis (PSC). Mdr2(-/-) mice provide a reliable in vivo model of PSC and develop characteristic biliary inflammation and fibrosis. We tested the hypothesis that the tumor suppressor protein menin is implicated in the progression of liver fibrosis and that menin expression can be regulated in the liver via microRNA-24 (miR-24). MATERIALS AND METHODS: Menin expression was measured in human PSC and Mdr2(-/-) mice...
May 11, 2017: Journal of Surgical Research
https://www.readbyqxmd.com/read/28595819/risk-factors-and-prediction-model-for-inpatient-surgical-site-infection-after-major-abdominal-surgery
#15
Aslam Ejaz, Carl Schmidt, Fabian M Johnston, Steve M Frank, Timothy M Pawlik
BACKGROUND: Surgical site infections (SSIs) are a common source of postoperative morbidity and a marker of surgical quality. The ability to predict the incidence of SSIs is limited and most models have poor predictive value. We sought to identify risk factors associated with SSIs and develop a prediction model for SSIs after major abdominal surgery. METHODS: A total of 1744 patients undergoing pancreatic, hepatobiliary, and colorectal resections between January 1, 2010 and August 31, 2013 at Johns Hopkins Hospital were identified...
May 11, 2017: Journal of Surgical Research
https://www.readbyqxmd.com/read/28595818/do-not-resuscitate-orders-and-high-risk-pediatric%C3%A2-surgery-professional-nuisance-or%C3%A2-medical%C3%A2-necessity
#16
Lauren M Baumann, Kibileri Williams, Fizan Abdullah, Richard J Hendrickson, Tolulope A Oyetunji
BACKGROUND: There is a paucity of data in the literature regarding end-of-life care and do-not-resuscitate (DNR) status of the pediatric surgical patient, although invasive procedures are frequently performed in very high risk and critically ill children. Despite significant efforts in adult medicine to enhance discussions around end-of-life care, little is known about similar endeavors in the pediatric population. METHODS: A retrospective review of the National Surgical Quality Improvement Program Pediatric database was performed...
May 11, 2017: Journal of Surgical Research
https://www.readbyqxmd.com/read/28587892/the-modified-frailty-index-to-predict-morbidity-and-mortality-for-retroperitoneal-sarcoma-resections
#17
Jiwon Sarah Park, Sarah B Bateni, Richard J Bold, Amanda R Kirane, Daniel J Canter, Robert J Canter
BACKGROUND: The modified frailty index (mFI) is an important method to risk-stratify surgical patients and has been validated for general surgery and selected surgical subspecialties. However, there are currently no data assessing the efficacy of the mFI to predict acute morbidity and mortality in patients undergoing surgery for retroperitoneal sarcoma. METHODS: Using the American College of Surgeons' National Surgical Quality Improvement Program from 2007 to 2012, we performed a retrospective analysis of patients with a diagnosis of primary malignant retroperitoneal neoplasm who underwent surgical resection...
May 11, 2017: Journal of Surgical Research
https://www.readbyqxmd.com/read/28587891/the-accessibility-readability-and-quality-of-online-resources-for-gender-affirming-surgery
#18
Christina R Vargas, Joseph A Ricci, Michelle Lee, Adam M Tobias, Daniel A Medalie, Bernard T Lee
BACKGROUND: The transgender population is disproportionally affected by health disparities related to access to care. In many communities, transgender specialists are geographically distant and locally available medical professionals may be unfamiliar with unique needs of transgender patients. As a result, use of Internet resources for information about gender affirming surgery is particularly important. This study simulates a patient search for online educational material about gender affirming surgery and evaluates the accessibility, readability, and quality of the information...
May 11, 2017: Journal of Surgical Research
https://www.readbyqxmd.com/read/28583756/thrombelastography-indicates-limitations-of-animal-models-of-trauma-induced-coagulopathy
#19
Gregory R Stettler, Ernest E Moore, Hunter B Moore, Peter J Lawson, Miguel Fragoso, Geoffrey R Nunns, Christopher C Silliman, Anirban Banerjee
BACKGROUND: Thrombelastography (TEG) has been used to characterize the coagulation changes associated with injury and shock. Animal models developed to investigate trauma-induced coagulopathy (TIC) have failed to produce excessive bleeding. We hypothesize that a native TEG will demonstrate marked differences in humans compared with these experimental models, which explains the difficulties in reproducing a clinically relevant coagulopathy in animal models. METHODS: Whole blood was collected from 138 healthy human volunteers, 25 swine and 66 Sprague-Dawley rats before experimentation...
May 11, 2017: Journal of Surgical Research
https://www.readbyqxmd.com/read/28583755/prognostic-significance-of-an-antenatal-magnetic-resonance-imaging-staging-system-on-airway-outcomes-of-fetal-craniofacial-venolymphatic-malformations
#20
David T Schindel, Diane Twickler, Natalie Frost, Deryk Walsh, Patricia Santiago-Munoz, Romaine Johnson
BACKGROUND: The aim of the article was to determine if anatomical findings on fetal magnetic resonance imaging (MRI) of venolymphatic malformations of the face and neck (VLMFN) can be used to create a staging system predictive of airway outcomes. METHODS: We reviewed 13 fetuses evaluated for VLMFN. Stage was assigned based on anatomical findings on fetal MRI. Stage I: no evidence of polyhydramnios with free egress of amniotic fluid and clear visualization of the aryepiglottic folds and larynx...
May 11, 2017: Journal of Surgical Research
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