journal
https://read.qxmd.com/read/38414222/free-flap-reconstruction-at-a-rural-based-tertiary-medical-college-hospital-barriers-and-outcomes
#21
JOURNAL ARTICLE
Deepak Hongaiah, Abhay K Kattepur, Eldo V George, Abhishek Mahadev M, Deepika Kenkere, Aswathappa Dasappa
BACKGROUND AND OBJECTIVES: In a rural-based setting, providing optimal treatment is often difficult owing to the limited resources and financial constraints being rampant in cancer care delivery. Oncological resections often result in large, complex defects requiring free flap reconstruction to achieve cosmetic and/or functional goals. This article focuses on our experience of starting and promoting microvascular reconstruction in a rural tertiary medical college hospital. METHODS: Retrospective observational study of patients undergoing free flap reconstruction for oncological indications was included...
February 27, 2024: Journal of Surgical Oncology
https://read.qxmd.com/read/38406980/operative-trends-following-the-adoption-of-nonoperative-management-of-rectal-cancer
#22
JOURNAL ARTICLE
Justin Brewer, Maseray Kamara, Marianne Huebner, Elias Taxakis, Karen Grajewski, Carole Ramm, Robert K Cleary
BACKGROUND: Differentiating clinical near-complete and complete responses (cCR) after neoadjuvant therapy (NT) is challenging in rectal cancer patients. We hypothesized that magnetic resonance imaging staging limitations for low rectal cancers may increase the proportion of abdominoperineal resection (APR) with permanent colostomy for those without a cCR. METHODS: Single institution retrospective analysis of rectal cancer cases before and after adoption of nonoperative "watch and wait" (W&W) pathway...
February 26, 2024: Journal of Surgical Oncology
https://read.qxmd.com/read/38396372/outcomes-of-rectal-cancer-patients-who-refuse-surgery-after-incomplete-clinical-response-to-neoadjuvant-therapy
#23
JOURNAL ARTICLE
Kevin P Labadie, Kristofer A Olson, Steven H Sun, Philip H G Ituarte, Mark Hanna, Yasmin Zerhouni, Lily L Lai, Stephen M Sentovich, Andreas M Kaiser, Kurt A Melstrom
BACKGROUND AND OBJECTIVES: Total mesorectal excision (TME) remains the standard of care for patients with rectal cancer who have an incomplete response to total neoadjuvant therapy (TNT). A minority of patients will refuse curative intent resection. The aim of this study is to examine the outcomes for these patients. METHODS: A retrospective cohort study of stage 1-3 rectal adenocarcinoma patients who underwent neoadjuvant chemoradiation therapy or TNT at a single institution...
February 23, 2024: Journal of Surgical Oncology
https://read.qxmd.com/read/38389278/points-to-consider-regarding-prophylactic-total-gastrectomy-in-germline-cdh1-variant-carriers
#24
REVIEW
Giovanni Corso, Jeremy L Davis, Vivian E Strong
Pathogenic germline CDH1 mutation confers high risk for developing diffuse gastric and lobular breast cancers in asymptomatic carriers. In these individuals, the estimated gastric cancer risk at 80 years of age is up to 70% for males and 56% for females. Due to this high-risk predisposition, prophylactic total gastrectomy is considered a unique life-saving approach in germline CDH1 carriers, as endoscopy often fails to detect early stage diffuse gastric carcinoma. However, surgical indication is controversial in some clinical contexts, with possible contraindications...
February 22, 2024: Journal of Surgical Oncology
https://read.qxmd.com/read/38385690/a-guide-for-addressing-sexual-health-in-breast-cancer-patients
#25
JOURNAL ARTICLE
Minji Kim, Jeanne Carter, Audree B Tadros, Nour Abuhdra, Jonas A Nelson, Carrie S Stern
PURPOSE: Sexual health concerns are common in breast cancer surgery but often overlooked. Yet, breast cancer patients want more sexual health information from their providers. We aimed to share ways for providers to address sexual health concerns with their breast cancer patients at different stages of the treatment process. METHODS: Experts in breast cancer treatments, surgeries, and sexual health at Memorial Sloan Kettering Cancer Center assembled to review the literature and to develop the recommendations...
February 22, 2024: Journal of Surgical Oncology
https://read.qxmd.com/read/38385654/intravenous-tranexamic-acid-reduces-complications-following-surgical-treatment-of-pathologic-fractures-of-the-lower-extremity
#26
JOURNAL ARTICLE
Brandon S Gettleman, Kevin C Liu, Mary K Richardson, Matthew Chen, Arad Talehakimi, Nathanael D Heckmann, Lawrence Menendez, Alexander B Christ
BACKGROUND AND OBJECTIVES: This study aimed to evaluate the postoperative complications associated with administering intravenous (IV) tranexamic acid (TXA) in patients undergoing surgical fixation for neoplastic pathologic fractures of the lower extremities. METHODS: Patients ≥18 years old who underwent surgical intervention for neoplastic pathologic lower extremity fractures from 2015 to 2021 were identified using the Premier Healthcare Database. This cohort was divided by TXA receipt on the index surgery day...
February 22, 2024: Journal of Surgical Oncology
https://read.qxmd.com/read/38348696/neuroendocrine-neoplasms-of-the-gallbladder-a-single-institute-analysis-of-outcomes-and-prognostic-factors
#27
JOURNAL ARTICLE
Kunal Nandy, Shraddha Patkar, Subhash Yadav, Vikas Ostwal, Anant Ramaswamy, Prabhat Bhargav, Mahesh Goel
INTRODUCTION: Neuroendocrine neoplasms (NENs) are classified as neuroendocrine tumors (NETs), neuroendocrine carcinomas (NECs), and mixed neuroendocrine and nonneuroendocrine neoplasms (MiNENs) according to World Health Organization classification. We present our experience of NENs of the gallbladder (GB) from a high-volume cancer hospital. MATERIALS AND METHODS: The present study is a retrospective analysis of all patients with GB NENs who presented between January 2015 and June 2023...
February 13, 2024: Journal of Surgical Oncology
https://read.qxmd.com/read/38333997/liver-resection-is-superior-to-tumor-ablation-in-patients-with-multifocal-hepatocellular-carcinoma
#28
JOURNAL ARTICLE
Hanna Kakish, Mohammed O Suraju, Erik S Davis, Abhinav Seth, Yong K Kwon, Hassan Aziz
INTRODUCTION: The management of T2 multifocal hepatocellular carcinoma (MHCC) is controversial, and the comparative impact of liver resection (LR) versus tumor ablation (TA) on survival continues to be debated. The aim of our study was to examine short- and long-term survival for LR and TA in a nationally representative cohort. We hypothesized that patients who underwent LR would have improved survival. METHODS: We utilized the National Cancer Database (2004-2015) to identify patients diagnosed with non-metastatic T2 MHCC...
February 9, 2024: Journal of Surgical Oncology
https://read.qxmd.com/read/38321865/the-improvement-of-postoperative-blood-pressure-and-associated-factors-in-patients-with-hormone-negative-adrenal-adenoma-and-hypertension
#29
JOURNAL ARTICLE
Jiaxing Sun, Yingchun Dong, Hanbo Wang, Xudong Guo, Ning Suo, Shangjian Li, Xiangbin Ren, Shaobo Jiang
OBJECTIVE: To investigate the effect of adrenal surgery on blood pressure (BP) improvements in patients with hormone-negative adrenal adenoma (HNA) concomitant with hypertension and analyze associated prognostic factors. METHODS: We retrospectively reviewed the clinical data of patients with HNA and hypertension and patients with aldosterone-producing adenoma (APA) and hypertension who underwent adrenal surgery at our center between 2019 and 2022. Hypertension outcomes were evaluated in all patients and subjects were divided into three groups according to follow-up BP and the administration of anti-hypertensive agents: a clinical curation group, an improvement group, and a no-improvement group...
February 6, 2024: Journal of Surgical Oncology
https://read.qxmd.com/read/38321584/gray-oncologic-areas
#30
JOURNAL ARTICLE
Hilde M Buiting, Gabe S Sonke
No abstract text is available yet for this article.
February 6, 2024: Journal of Surgical Oncology
https://read.qxmd.com/read/38316936/postoperative-infectious-complications-worsen-oncologic-outcomes-following-pancreaticoduodenectomy-for-pancreatic-ductal-adenocarcinoma
#31
JOURNAL ARTICLE
Hussein H Khachfe, Abdulrahman Y Hammad, Samer AlMasri, Ibrahim Nassour, Rudy ElAsmar, Hao Liu, Annissa de Silva, Jasmine Kraftician, Kenneth K Lee, Amer H Zureikat, Alessandro Paniccia
BACKGROUND: Pancreaticoduodenectomy (PD) remains the only curative option for patients with pancreatic adenocarcinoma (PDAC). Infectious complications (IC) can negatively impact patient outcomes and delay adjuvant therapy in most patients. This study aims to determine IC effect on overall survival (OS) following PD for PDAC. STUDY DESIGN: Patients who underwent PD for PDAC between 2010 and 2020 were identified from a single institutional database. Patients were categorized into two groups based on whether they experienced IC or not...
February 5, 2024: Journal of Surgical Oncology
https://read.qxmd.com/read/38314575/impact-of-deep-muscle-invasion-on-nodal-status-and-survival-in-patients-with-pt2-esophageal-squamous-cancer
#32
JOURNAL ARTICLE
Cheng-Yi Yan, Yi-Min Gu, Gui-Dong Shi, Qi-Xin Shang, Han-Lu Zhang, Yu-Shang Yang, Wen-Ping Wang, Yong Yuan, Long-Qi Chen
BACKGROUND: Whether T2 esophageal squamous cell carcinoma should be subclassified remains controversial. We aimed to investigate the impact of the depth of muscularis propria invasion on nodal status and survival outcomes. METHODS: We identified patients with pT2 esophageal squamous cell carcinoma who underwent primary surgery from January 2009 to June 2017. Clinical data were extracted from prospectively maintained databases. Tumor muscularis propria invasion was stratified into superficial or deep...
February 5, 2024: Journal of Surgical Oncology
https://read.qxmd.com/read/38311813/the-application-of-three-dimensional-custom-made-prostheses-in-chest-wall-reconstruction-after-oncologic-sternal-resection
#33
JOURNAL ARTICLE
Chengxin Liu, Haipeng Sun, Feng Lin
BACKGROUND AND OBJECTIVES: As one of the cutting-edge advances in the field of reconstruction, three-dimensional (3D) printing technology has been constantly being attempted to assist in the reconstruction of complicated large chest wall defects. However, there is little literature assessing the treatment outcomes of 3D printed prostheses for chest wall reconstruction. This study aimed to analyze the surgical outcomes of 3D custom-made prostheses for the reconstruction of oncologic sternal defects and to share our experience in the surgical management of these rare and complex cases...
February 4, 2024: Journal of Surgical Oncology
https://read.qxmd.com/read/38305061/malignant-upgrade-rate-and-associated-clinicopathologic-predictors-for-concordant-intraductal-papilloma-without-atypia-%C3%A2-a-systematic-review-and-meta-analysis
#34
REVIEW
Niamh Keating, Jevan Cevik, David Hopkins, Jocelyn Lippey
Previously reported upgrade rates for benign breast intraductal papilloma (IDP) are widely variable. However, many previous studies have failed to consider radiologic-pathologic discordance of lesions. This review aims to synthesize malignant upgrade data for benign, concordant IDP at surgical excision. Thirteen studies were included in our meta-analysis. The pooled estimate for percentage underestimation of carcinoma was 1.4% (95% CI: 0.8%-2.0%). We conclude that these lesions can be safely managed by active surveillance...
February 2, 2024: Journal of Surgical Oncology
https://read.qxmd.com/read/38288783/patient-reported-outcomes-after-multivisceral-resection-for-advanced-rectal-cancers-in-female-patients
#35
JOURNAL ARTICLE
Mufaddal Kazi, Katyayani Choubey, Pooja Patil, Dushyant Jaiswal, Sejal Ajmera, Ashwin Desouza, Avanish Saklani
INTRODUCTION: Multivisceral resections for rectal cancer can lead to long-term functional disturbances. This study aims to evaluate the quality-of-life outcomes in female patients who underwent multivisceral resection for rectal cancer, specifically focusing on urinary and sexual functions. METHODS: A cross-sectional study was conducted on female patients who underwent multivisceral rectal resections. Quality of life was assessed using the EORTC QLQ-CR29. RESULTS: Out of 198 female patients that underwent multivisceral resections, 69 were assessable for functional outcomes...
January 30, 2024: Journal of Surgical Oncology
https://read.qxmd.com/read/38287517/internal-hemipelvectomy-a-single-institution-s-learning-curve-and-longitudinal-experience
#36
JOURNAL ARTICLE
Rajko S Vucicevic, Athan G Zavras, Michael P Fice, Zeeshan A Khan, Charles Gusho, Matthew Gasparro, Steven Gitelis, Alan Blank, Matthew W Colman
BACKGROUND AND OBJECTIVES: Wide margin resection for pelvic tumors via internal hemipelvectomy is among the most technically challenging procedures in orthopedic oncology. As such, surgeon experience and technique invariably affect patient outcomes. The aim of this clinical study was to assess how an individual surgeon's experiences and advancements in technology and techniques in the treatment of internal hemipelvectomy have impacted patient outcomes at our institution. METHODS: This study retrospectively examined a single tertiary academic institution's consecutive longitudinal experience with internal hemipelvectomy for primary sarcoma or pelvic metastases over a 26-year period between the years 1994 and 2020...
January 29, 2024: Journal of Surgical Oncology
https://read.qxmd.com/read/38263585/clinical-outcomes-in-patients-with-adamantinoma-report-from-the-bone-and-soft-tissue-tumor-registry-in-japan
#37
JOURNAL ARTICLE
Junya Shimizu, Makoto Emori, Yasutaka Murahashi, Akira Kawai, Atsushi Teramoto
BACKGROUND: Adamantinomas are rare malignant bone tumors. Due to their low incidence, there are few reports on the clinical results of adamantinoma. OBJECTIVES: This study aims to clarify outcomes in patients with adamantinoma using data from the National Bone and Soft Tissue Tumor Registry. METHODS: From 2006 to 2019, 38 cases of tibial origin were included. Twenty-four were male and 14 were female, with a mean age of 37 (6-87) years and a mean follow-up of 35 (1-128) months...
January 23, 2024: Journal of Surgical Oncology
https://read.qxmd.com/read/38247263/seroma-formation-after-mastectomy-a-systematic-review-and-network-meta-analysis-of-different-flap-fixation-techniques
#38
REVIEW
Merel A Spiekerman van Weezelenburg, Jean H T Daemen, Sander M J van Kuijk, Elisabeth R M van Haaren, Alfred Janssen, Yvonne L J Vissers, Geerard L Beets, James van Bastelaar
Flap fixation is the most promising solution to prevent seroma formation after mastectomy. In this systematic review with network meta-analysis (NMA), three different techniques were compared. The NMA included 25 articles, comprising 3423 patients, and revealed that sutures are superior to tissue glue in preventing clinically significant seroma. In addition, running sutures seemed to be superior to interrupted sutures. An RCT comparing these suture techniques seems necessary, given the quality and nature of existing literature...
January 21, 2024: Journal of Surgical Oncology
https://read.qxmd.com/read/38247024/rates-of-breast-reconstruction-uptake-and-attitudes-toward%C3%A2-breast-cancer-and-survivorship-among-south-asians-a-literature-review
#39
REVIEW
Prottusha Sarkar, Kristin N Huffman, Tokoya Williams, Avneet Deol, Isabella Zorra, Tarifa Adam, Rachel Donaldson, Umer Qureshi, Karan Gowda, Robert D Galiano
Our aim in this review was to ascertain rates of breast reconstruction among South Asian patients and identify attitudes towards breast cancer, survivorship, and breast reconstruction. Mastectomy rates for South Asian patients ranged from 52% to 77% and reconstruction following mastectomy varied from 0% to 14%. A negative perception of cancer, fears of social isolation, and taboos around breasts can prevent South Asian women from receiving surgical care after a breast cancer diagnosis.
January 21, 2024: Journal of Surgical Oncology
https://read.qxmd.com/read/38239092/recurrence-risk-stratification-using-the-beppu-score-and-selection-of-perioperative-chemotherapy-for-colorectal-liver-metastases
#40
REVIEW
Toru Beppu, Kensuke Yamamura, Katsunori Imai, Hiromitsu Hayashi, Yuji Miyamoto
The annual postoperative disease-free survival for colorectal liver metastases can be easily estimated by weighting six preoperative clinical parameters (Beppu score). We identified three recurrence-risk stratification groups: the low (≤6 points), moderate (7-10 points), and high-risk (≥11 points). For low-, moderate-, and high-risk patients, hepatectomy alone, hepatectomy with adjuvant chemotherapy, and hepatectomy with preoperative chemotherapy are recommended, respectively. The Beppu score enables the decision on the necessity and timing of perioperative chemotherapy...
January 18, 2024: Journal of Surgical Oncology
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