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Journal of Surgical Oncology

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https://www.readbyqxmd.com/read/28727901/carbon-ion-radiotherapy-for-isolated-para-aortic-lymph-node-recurrence-from-colorectal-cancer
#1
Yuka Isozaki, Shigeru Yamada, Shohei Kawashiro, Shigeo Yasuda, Naomi Okada, Daniel Ebner, Hiroshi Tsuji, Tadashi Kamada, Hisahiro Matsubara
BACKGROUND: The safety and effectiveness of carbon-ion radiotherapy (CIRT) for isolated para-aortic lymph node (PALN) metastasis was evaluated retrospectively. METHODS: CIRT for isolated PALN metastasis from CRC was performed in 34 cases from June 2006 to August 2015 in our institute. A median dose of 52.8 Gy(RBE) (range, 48-52.8 Gy(RBE)) was delivered with a median daily dose of 4.4 Gy(RBE) (range, 4.0-4.4 Gy(RBE)). RESULTS: The median follow-up duration for all patients was 24...
July 20, 2017: Journal of Surgical Oncology
https://www.readbyqxmd.com/read/28727898/three-dimensional-printing-for-patient-counseling
#2
LETTER
Rex Wh Hui
No abstract text is available yet for this article.
July 20, 2017: Journal of Surgical Oncology
https://www.readbyqxmd.com/read/28715150/intraoperative-radiotherapy-patient-selection-management-and-follow-up
#3
REVIEW
Dennis R Holmes, Robert Zimmerman
Intraoperative partial breast radiotherapy is an alternative or an adjunct to fractionated whole breast irradiation for the administration of adjuvant radiotherapy in breast cancer following breast conserving surgery. Establishing intraoperative radiotherapy as a therapeutic modality requires a multidisciplinary approach to patient selection, workup, surgery, radiation protocols, chemotherapy, and patient follow up. In this article, we review the published evidence for best clinical practice, as a guide to the introduction of intraoperative radiotherapy for breast cancer treatment...
July 17, 2017: Journal of Surgical Oncology
https://www.readbyqxmd.com/read/28715140/the-natural-history-of-thin-melanoma-and-the-utility-of-sentinel-lymph-node-biopsy
#4
Alison B Durham, Jennifer L Schwartz, Lori Lowe, Lili Zhao, Andrew G Johnson, Kelly L Harms, Christopher K Bichakjian, Amy P Orsini, Scott A McLean, Carol R Bradford, Mark S Cohen, Timothy M Johnson, Michael S Sabel, Sandra L Wong
BACKGROUND AND OBJECTIVES: Current literature may overestimate the risk of nodal metastasis from thin melanoma due to reporting of data only from lesions treated with SLNB. Our objective was to define the natural history of thin melanoma, assessing the likelihood of nodal disease, in order to guide selection for SLNB. METHODS: Retrospective review. The primary outcome was the rate of nodal disease. Clinicopathologic factors were evaluated to find associations with nodal disease...
July 17, 2017: Journal of Surgical Oncology
https://www.readbyqxmd.com/read/28703911/low-incidence-of-metastasis-and-recurrence-from-cutaneous-squamous-cell-carcinoma-found-in-a-uk-population-do-we-need-to-adjust-our-thinking-on-this-rare-but-potentially-fatal-event
#5
Toby G Nelson, Richard E Ashton
BACKGROUND AND METHODS: Cutaneous squamous cell carcinoma (cSCC) is the commonest skin cancer with metastatic potential, however, reported rates of metastasis varies greatly. All cases of primary cSCC on the Isle of Wight between 2005 and 2014 were identified and retrospectively followed for recurrence and/or metastasis. Primary outcome was to identify the rate of metastasis/recurrence from cSCC. Secondary outcomes included associated risk factors for metastasis/recurrence, death from cSCC, and time from diagnosis of primary cSCC to event...
July 13, 2017: Journal of Surgical Oncology
https://www.readbyqxmd.com/read/28703900/rapid-genetic-counseling-and-testing-in-newly-diagnosed-breast-cancer-patients-and-health-professionals-attitudes-experiences-and-evaluation-of-effects-on-treatment-decision-making
#6
Marijke R Wevers, Neil K Aaronson, Eveline M A Bleiker, Daniela E E Hahn, Titia Brouwer, Thijs van Dalen, Evert B Theunissen, Bart van Ooijen, Marnix A de Roos, Paul J Borgstein, Bart C Vrouenraets, Eline Vriens, Wim H Bouma, Herman Rijna, Johannes P Vente, Marianne A Kuenen, Jacoline van der Sanden-Melis, Arjen J Witkamp, Emiel J Th Rutgers, Senno Verhoef, Margreet G E M Ausems
BACKGROUND: Rapid genetic counseling and testing (RGCT) in newly diagnosed high-risk breast cancer (BC) patients may influence surgical treatment decisions. To successfully integrate RGCT in practice, knowledge of professionals', and patients' attitudes toward RGCT is essential. METHODS: Between 2008 and 2010, we performed a randomized clinical trial evaluating the impact of RGCT. Attitudes toward and experience with RGCT were assessed in 265 patients (at diagnosis, 6- and 12-month follow-up) and 29 medical professionals (before and after the recruitment period)...
July 13, 2017: Journal of Surgical Oncology
https://www.readbyqxmd.com/read/28703886/dual-energy-ct-a-possible-new-method-to-assess-regression-of-rectal-cancers-after-neoadjuvant-treatment
#7
Issam Al-Najami, Henrik C Drue, Robert Steele, Gunnar Baatrup
BACKGROUND AND OBJECTIVES: The measurement of tumor regression after neoadjuvant oncological treatment has gained increasing interest because it has a prognostic value and because it may influence the method of treatment in rectal cancer. The assessment of tumor regression remains difficult and inaccurate with existing methods. Dual Energy Computed Tomography (DECT) enables qualitative tissue differentiation by simultaneous scanning with different levels of energy. We aimed to assess the feasibility of DECT in quantifying tumor response to neoadjuvant therapy in loco-advanced rectal cancer...
July 13, 2017: Journal of Surgical Oncology
https://www.readbyqxmd.com/read/28703880/performance-of-prognostic-scores-and-staging-systems-in-predicting-long-term-survival-outcomes-after-surgery-for-intrahepatic-cholangiocarcinoma
#8
Stefan Buettner, Boris Galjart, Jeroen L A van Vugt, Fabio Bagante, Sorin Alexandrescu, Hugo P Marques, Jorge Lamelas, Luca Aldrighetti, T Clark Gamblin, Shishir K Maithel, Carlo Pulitano, Georgios A Margonis, Matthew Weiss, Todd W Bauer, Feng Shen, George A Poultsides, J Wallis Marsh, Jan N M IJzermans, Bas Groot Koerkamp, Timothy M Pawlik
INTRODUCTION: We sought to validate the commonly used prognostic models and staging systems for intrahepatic cholangiocarcinoma (ICC) in a large multi-center patient cohort. METHODS: The overall (OS) and disease free survival (DFS) prognostic discriminatory ability of various commonly used models were assessed in a large retrospective cohort. Harrell's concordance index (c-index) was used to determine accuracy of model prediction. RESULTS: Among 1054 ICC patients, median OS was 37...
July 13, 2017: Journal of Surgical Oncology
https://www.readbyqxmd.com/read/28703872/lymph-node-station-ratio-revised-nodal-category-for-resected-esophageal-squamous-cell-carcinoma-patients
#9
Xiayu Fu, Qianwen Liu, Kongjia Luo, Jing Wen, Hong Yang, Yi Hu, Xinye Wang, Peng Lin, Jianhua Fu
OBJECTIVES: The objective of this study was to evaluate a revised nodal category based on the value of the lymph node (LN) station ratio (SR, metastatic LN stations/examined LN stations) in esophageal squamous cell carcinoma (ESCC) patients. METHODS: Data were obtained from 857 ESCC patients who underwent primary radical esophagectomy. Prognostic performance was evaluated using the Harrell concordance index (C-index), Akaike information criterion (AIC), and likelihood ratio χ(2) test (LR χ(2) test)...
July 13, 2017: Journal of Surgical Oncology
https://www.readbyqxmd.com/read/28699269/determinants-of-short-and-long-term-outcomes-in-patients-undergoing-immediate-breast-reconstruction-following-neoadjuvant-chemotherapy
#10
Craig A Wengler, Stephanie A Valente, Zahraa AlHilli, Neil M Woody, Julia H Muntean, Jame Abraham, Rahul D Tendulkar, Risal Djohan, Colin O'Rourke, Joseph P Crowe, Stephen R Grobmyer
BACKGROUND: We evaluated oncologic outcomes and complications of skin-sparing mastectomy (SSM) and nipple-sparing mastectomy (NSM) with immediate reconstruction (IR) after neoadjuvant chemotherapy (NAC) in patients with early-stage and locally advanced breast cancer (BC). METHODS: BC patients from 2000 to 2014 treated with NAC followed by SSM/NSM and IR were reviewed. Patient demographics, tumor characteristics, NAC response, complications, and recurrence were analyzed...
July 11, 2017: Journal of Surgical Oncology
https://www.readbyqxmd.com/read/28695707/comparison-of-long-term-clinical-outcomes-among-different-vascularized-lymph-node-transfers-6-year-experience-of-a-single-center-s-approach-to-the-treatment-of-lymphedema
#11
Pedro Ciudad, Mouchammed Agko, John Jaime Perez Coca, Oscar J Manrique, Wei-Ling Chang, Fabio Nicoli, Shih-Heng Chen, Hung-Chi Chen
BACKGROUND: This study evaluated the long-term clinical outcomes among different vascularized lymph node transfers (VLNT) used at our institution. METHODS: Between July 2010 and July 2016, all patients with International Society of Lymphology (ISL) stages II-III who underwent VLNT were evaluated. Demographic and clinical data (limb circumference, infectious episodes, lymphoscintigraphic studies) were recorded pre-operatively. Clinical outcomes, complications, and additional excisional procedures were analyzed post-operatively...
July 10, 2017: Journal of Surgical Oncology
https://www.readbyqxmd.com/read/28695641/favorable-factors-for-preserving-bladder-function-after-nerve-sparing-radical-hysterectomy-a-protocol-based-validation-study
#12
Hee Seung Kim, Miseon Kim, Yanlin Luo, Maria Lee, Yong Sang Song
OBJECTIVES: To investigate favorable factors of nerve-sparing radical hysterectomy (NSRH) for preserving the pelvic autonomic nerves and subsequent bladder function and to compare the safety between NSRH and conventional radical hysterectomy (CRH) for cervical cancer. METHODS: We recruited 87 consecutive patients with IB1-IIA cervical cancer who underwent NSRH, and reviewed the information of 81 patients who received CRH for historical comparisons. One gynaecologic oncologist performed all operations...
July 10, 2017: Journal of Surgical Oncology
https://www.readbyqxmd.com/read/28695608/integration-of-sick-lobe-hypothesis-with-concept-of-field-cancerisation-for-a-personalised-surgical-margin-for-breast-conserving-surgery
#13
LETTER
Mona P Tan
No abstract text is available yet for this article.
July 10, 2017: Journal of Surgical Oncology
https://www.readbyqxmd.com/read/28695575/combining-the-sick-lobe-theory-with-markers-of-field-cancerization-for-refinement-of-a-personalized-surgical-margin
#14
LETTER
Katarina Leyba, Radha Swaminathan, Anna Jones, John Russell, Nancy Joste, Marco Bisoffi, Kristina Trujillo
No abstract text is available yet for this article.
July 10, 2017: Journal of Surgical Oncology
https://www.readbyqxmd.com/read/28695567/tc-99m-tilmanocept-versus-tc-99m-sulfur-colloid-in-breast-cancer-sentinel-lymph-node-identification-results-from-a-randomized-blinded-clinical-trial
#15
Jonathan T Unkart, Ava Hosseini, Anne M Wallace
INTRODUCTION: No prior trials have compared sentinel lymph node (SLN) identification outcomes between Tc-99m tilmanocept (TcTM) and Tc-99m sulfur colloid (TcSC) in breast cancer (BC). METHODS: We report on the secondary outcomes from a randomized, double-blinded, single surgeon clinical trial comparing post-injection site pain between TcTM and TcSC. Patients were randomized to receive a preoperative single, peritumoral intradermal injection of TcTM or TcSC. The number of total, "hot", and blue nodes detected and removed were compared between groups...
July 10, 2017: Journal of Surgical Oncology
https://www.readbyqxmd.com/read/28695566/portal-vein-territory-identification-using-indocyanine-green-fluorescence-imaging-technical-details-and-short-term-outcomes
#16
Yuta Kobayashi, Yoshikuni Kawaguchi, Kosuke Kobayashi, Kazuhiro Mori, Junichi Arita, Yoshihiro Sakamoto, Kiyoshi Hasegawa, Norihiro Kokudo
BACKGROUND AND OBJECTIVES: Portal vein (PV) territory identification during liver resection may be performed using indocyanine green (ICG) fluorescence imaging technique. However, the technical details of the fluorescence staining technique have not been fully elucidated. This study was performed to demonstrate the technical details of PV territory identification using fluorescence imaging and evaluates the short-term outcomes. METHODS: From 2011 to 2015, 105 underwent liver resection at the University of Tokyo Hospital with one of the following fluorescence staining techniques by transhepatic PV injection or intravenous injection of ICG: single staining (n = 36), multiple staining (n = 31), counterstaining (n = 22), negative staining (n = 13), or paradoxical negative staining (n = 3)...
July 10, 2017: Journal of Surgical Oncology
https://www.readbyqxmd.com/read/28672101/impact-of-neoadjuvant-chemotherapy-on-surgical-outcomes-among-patients-with-hormone-receptor-positive-breast-cancer
#17
Andrew N Hage, Christina Capriccioso, Julia Brennan, Brendan Heiden, Alexander Zheutlin, Michael S Sabel
BACKGROUND: Pathologic complete response (pCR) after neoadjuvant chemotherapy (NACT) is a surrogate for outcome, but not necessarily conversion to BCT eligibility. We sought to examine the impact of NACT on surgical decision making among HR+ patients. METHODS: Our IRB-approved breast cancer database was queried for patients who underwent NACT, including the clinicopathologic data and surgeon's pre- and post-NACT assessment. Surgical conversion rate (SCR) was defined as patients ineligible for BCT prior to NACT, who were given the choice following NACT...
July 3, 2017: Journal of Surgical Oncology
https://www.readbyqxmd.com/read/28672078/surgery-for-recurrence-in-retroperitoneal-leiomyosarcoma-is-it-all-about-selection
#18
EDITORIAL
William W Tseng, Alessandro Gronchi
No abstract text is available yet for this article.
July 3, 2017: Journal of Surgical Oncology
https://www.readbyqxmd.com/read/28672049/diagnostic-and-prognostic-role-of-sf1-igf2-ki67-p53-adiponectin-and-leptin-receptors-in-human-adrenal-cortical-tumors
#19
Anna Babińska, Rafał Pęksa, Piotr Wiśniewski, Renata Świątkowska-Stodulska, Krzysztof Sworczak
BACKGROUND: The authors have examined the immunohistochemical expression of several proteins and their relationship with adrenal cortical carcinoma (ACC) diagnosis and progression. MATERIALS AND METHODS: A total of 83 patients with benign and malignant adrenal cortex tumors operated on in a single center were included in the study. Expression of the following proteins was examined: steroidogenic factor 1 (SF1), insulin growth factor 2 (IGF2), Ki67, p53, as well as adiponectin (Adipo R1, Adipo R2), and leptin (Ob-R) receptors...
July 3, 2017: Journal of Surgical Oncology
https://www.readbyqxmd.com/read/28672047/slnb-in-cutaneous-scc-a-review-of-the-current-state-of-literature-and-the-direction-for-the-future
#20
REVIEW
Omeed Ahadiat, Shauna Higgins, Adam Sutton, Alexandre Ly, Ashley Wysong
The concept of the sentinel lymph node biopsy (SLNB) has been universally accepted for melanoma, however, remains controversial for squamous cell carcinoma (SCC). We performed a quantitative review on 260 cases of SCC that had a SLNB. The positivity rate was found to be 14.6%. Literature was qualitatively reviewed to determine whether a positive SLNB has any bearing on prognosis in SCC cases, finding a significant relationship between poor prognosis and a positive SLN (P = 0.0082).
July 3, 2017: Journal of Surgical Oncology
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