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Journal of Surgical Oncology

Chun-Kai Liao, Jy-Ming Chiang, Wen-Sy Tsai, Jeng-Fu You, Pao-Shiu Hsieh, Hsin-Yuan Hung, Hong-Hwa Chen, Rei-Ping Tang, Jinn-Shiun Chen, Chien-Yuh Yeh
BACKGROUND AND OBJECTIVES: We aim to investigate whether a difference exists between right-sided and left-sided colon cancer at the same disease stage and subsequent liver metastasis and identify whether tumor location can independently influence survival. METHODS: Right-sided colon cancer was defined as malignancy arising from the cecum to the transverse colon; left-sided colon cancer was defined as malignancy arising from the splenic flexure to the sigmoid colon...
November 8, 2018: Journal of Surgical Oncology
Darren W Chua, Koh Ye Xin, Liew Yi Xin, Chung-Yip Chan, Ser-Yee Lee, Peng-Chung Cheow, Pierce K Chow, Alexander Y Chung, London L Ooi, Brian Kp Goh
BACKGROUND AND OBJECTIVES: Spontaneous rupture of Hepatocellular Carcinoma (srHCC) is a life-threatening emergency. We sought to identify the pre-operative predictors of early tumor recurrence/mortality including the role of inflammatory indices after partial hepatectomy for srHCC. METHODS: Between 2000-2015, 79 patients with srHCC were identified to have undergone upfront partial hepatectomy following srHCC. Clinicopathologic data were retrospectively analyzed to identify pre-operative predictors of early (<1 year) recurrence and mortality...
November 6, 2018: Journal of Surgical Oncology
Charles Honoré, Matthieu Faron, Olivier Mir, Leila Haddag-Miliani, Sarah Dumont, Philippe Terrier, Cecile LePéchoux, Angela Botticella, Julien Adam, Axel Le Cesne
BACKGROUND: Despite surgery, many patients experience locoregional recurrence (LR), the optimum treatment of which is still debated. METHODS: All 297 consecutive patients operated for a nonmetastatic primary retroperitoneal soft tissue sarcoma (RPS) between 1994 and 2017 were retrospectively analyzed to report our experience in treating LR. RESULTS: After a median follow-up of 97 months, 55 patients (19%) developed LR. The first site of recurrence was locoregional in 100% with associated peritoneal metastases in 45% and distant metastases in 5%...
November 6, 2018: Journal of Surgical Oncology
Andrea Viti, Laura Socci, Miguel Congregado, Mahmoud Ismail, Dania Nachira, Carlos Galvez Muñoz, Sergio Bolufer, Jens C Rückert, Stefano Margaritora, Alberto Terzi
BACKGROUND AND OBJECTIVES: Prolonged air leaks (PAL) are the most frequent complication after lobectomy for non-small cell lung cancer, even in case of minimally invasive approaches. We developed a novel score to identify high-risk patients for PAL during minimally invasive lobectomy. METHODS: A dedicated database was created. We investigated preoperative candidate features and specific intraoperative variables. Univariate and subsequent logistic regression analysis with bootstrap resampling have been used...
November 6, 2018: Journal of Surgical Oncology
Kemal H Turkoz, Bulent Erol, Ipek E Seven
BACKGROUND AND OBJECTIVES: The reasons behind the removal of the biopsy tract in osteosarcomas are not well known, and studies about tumor seeding in the biopsy tract have generated conflicting results. This study is designed to evaluate the presence and possible clinical significance of tumor cell seeding in the biopsy tract of osteosarcomas. METHODS: We prospectively evaluated 55 cases of osteosarcomas for tumor cell seeding and other clinical and pathologic prognostic parameters...
November 6, 2018: Journal of Surgical Oncology
Hanumant Chouhan, Tarik Sammour, Michelle L Thomas, James W Moore
PURPOSE: The predictive role of biomarkers in colon cancer is still being defined. The aim of this study is to determine the interaction between BRAF mutation and microsatellite instability (MSI) status in determining survival benefit after adjuvant 5-FU based chemotherapy in stage III colon cancer. METHODS: We performed a retrospective cohort study including all curatively resected stage III colon cancer cases over a 33-year period. A clinicopathological database was collated (adjuvant chemotherapy, age, gender, obstruction, perforation, tumor location, grade, mucin, nodal stage, extramural vascular, and perineural invasion)...
November 6, 2018: Journal of Surgical Oncology
Meifeng He, Zhanwu Jiang, Chunguang Wang, Zhiwei Hao, Jie An, Jiankai Shen
BACKGROUND: This meta-analysis was conducted to evaluate the diagnostic value of near-infrared (NIR) or fluorescent indocyanine green (ICG) guided sentinel lymph node (SLN) mapping in gastric cancer (GC). METHODS: This meta-analysis was registered at the PROSPERO. Clinical studies were retrieved from the electronic database Pubmed, Embase, Medline, Web of science, and the Cochrane Library. Quality assessment was conducted by an adapted checklist of QUADAS-2. A bivariate mixed-effects model was used to pool the data...
October 31, 2018: Journal of Surgical Oncology
Xin Guo, Zheng Peng, Xiaohui Lv, Jianxin Cui, Kecheng Zhang, Jiyang Li, Naizhong Jin, Hongqi Xi, Bo Wei, Lin Chen
BACKGROUND AND OBJECTIVES: We compared the clinical outcomes of laparoscopic and open spleen-preserving splenic hilar lymphadenectomy (LSPL and OSPL) for gastric cancer. METHODS: We performed a single-center, randomized, controlled trial to compare the short-term surgical outcomes between LSPL and OSPL. The study was registered in (NCT02980861). RESULTS: A total of 222 patients were enrolled (114 in the LSPL group and 108 in the OSPL group)...
October 31, 2018: Journal of Surgical Oncology
Georgios Gemenetzis, Vincent P Groot, Alex B Blair, Ding Ding, Sameer S Thakker, Elliot K Fishman, John L Cameron, Martin A Makary, Matthew J Weiss, Christopher L Wolfgang, Jin He
BACKGROUND: The incidence of occult metastatic disease (OMD) in pancreatic ductal adenocarcinoma (PDAC) and associated risk factors are largely unknown. METHODS: We identified all patients with PDAC, who had an aborted oncologic operation due to OMD within a 10-year period. The cases were matched to a cohort of resected PDAC patients on a 1:3 ratio, based on age and sex, for comparison of preoperative clinical characteristics and potential risk factors for OMD...
October 31, 2018: Journal of Surgical Oncology
Allison N Martin, Allison Silverstein, Robinson Ssebuufu, Joseph Lule, Pacifique Mugenzi, Alexandra Fehr, Tharcisse Mpunga, Lawrence N Shulman, Paul H Park, Ainhoa Costas-Chavarri
BACKGROUND: Gastric cancer is the fifth most common cancer in Eastern Africa. Diagnostic delays in low-resource countries result in advanced disease presentation. We describe perioperative management of gastric cancer in Rwanda. METHODS: A retrospective review of records at three hospitals was performed to identify gastric adenocarcinoma cases from January 2012 to June 2016. Multiple perioperative and tumor-related variables were collected. Descriptive and bivariate analyses were performed...
October 31, 2018: Journal of Surgical Oncology
Quetzalihuitl Arroyo-Martinez, Won Ho Han, Bang Wool Eom, Hong Man Yoon, Young Il Kim, Soo Jeong Cho, Jong Yeul Lee, Chan Gyoo Kim, Salvador Morales-Conde, Javier Padillo-Ruiz, Myeong-Cherl Kook, Il Ju Choi, Young Woo Kim, Keun Won Ryu
BACKGROUND AND OBJECTIVES: Additional surgery should be done after non-curative endoscopic resection (ER) in early gastric cancer (EGC) due to the risk of lymph node metastasis (LNM). However, the distribution pattern of LNM in these patients is complicated and unpredictable. The aim of this study is to identify any different distribution patterns of LNM in patients with EGC who underwent additional surgery after non-curative (ER) comparing to those without ER. METHODS: Patients who underwent surgery for EGC between 2001 and 2016 were included...
October 27, 2018: Journal of Surgical Oncology
Kyeong-Hyeon Byeon, Yun-Sok Ha, Seock-Hwan Choi, Bum Soo Kim, Hyun Tae Kim, Eun Sang Yoo, Tae Gyun Kwon, Jun Nyung Lee, Tae-Hwan Kim
BACKGROUND AND OBJECTIVES: The adrenal gland is a frequent site for metastasis, and a solitary adrenal mass is often observed during staging workup or imaging follow-up in patients with extra-adrenal malignancy. To create an appropriate management plan, it is essential to distinguish between benign adrenal lesions and metastasis in patients with extra-adrenal cancer having solitary adrenal masses. Therefore, here we evaluated the predictive factors for adrenal metastasis in patients with extra-adrenal malignancy having solitary adrenal mass...
October 27, 2018: Journal of Surgical Oncology
Viraj A Master, Cecilia G Ethun, David A Kooby, Charles A Staley, Shishir K Maithel
INTRODUCTION: We report the evolution of the largest, contemporary, single-institution experience with this complex procedure to highlight the value of a cross-discipline, team-based approach. METHODS: Patients from a prospectively maintained database who underwent resection of renal cell carcinoma (RCC) with inferior vena cava (IVC) tumor thrombus from 2005 to 2016 at a single-institution were included for analysis. RESULTS: Of 140 patients, 102 (73%) had tumor thrombus below the level of the hepatic vein confluence, and 96 (69%) were performed for curative-intent, while 43 (31%) were cytoreductive procedures for clinical trial consideration...
October 17, 2018: Journal of Surgical Oncology
Naveena A N Kumar, Kamlesh Verma, Rajesh S Shinde, Praveen Kammar, Rohit Dusane, Ashwin Desouza, Vikas Ostwal, Prachi Patil, Reena Engineer, George Karimundackal, C S Pramesh, Avanish Saklani
BACKGROUND: This study was undertaken to evaluate the effect of change in policy of computed tomography (CT) scan of the thorax in staging and follow-up of colorectal cancer (CRC). Another objective was to review the outcomes following pulmonary metastasectomies (Pmets) and to determine the prognostic factors affecting outcomes. METHODS: This is a retrospective analysis from a prospective cohort database of patients, who underwent Pmet for CRC origin from August 2004 to February 2016...
October 17, 2018: Journal of Surgical Oncology
Jianlu Kong, Wenjie Sun, Wenyuan Zhu, Chuanxia Liu, Honghe Zhang, Huiming Wang
BACKGROUND AND OBJECTIVES: Long noncoding RNAs (lncRNAs) play key roles in carcinoma metastasis. We aimed to investigate lncRNA LINC01133 in oral squamous cell carcinoma (OSCC) metastasis. METHODS: The RNA levels of LINC01133 and growth and differentiation factor 15 (GDF15) in tissue samples from OSCC patients, and OSCC cell lines were tested by real-time quantitative polymerase chain reaction (RT-qPCR). SPSS20.0 was used to perform statistical analysis of LINC01133 expression in clinical samples and correlate expression of LINC01133 and GDF15...
October 17, 2018: Journal of Surgical Oncology
Luca Roncati, Francesco Piscioli
No abstract text is available yet for this article.
September 27, 2018: Journal of Surgical Oncology
Federica Domati, Luca R Bonetti, Valeria Barresi, Maurizio Zizzo, Antonio Manenti
No abstract text is available yet for this article.
September 9, 2018: Journal of Surgical Oncology
Mark C Kendall, Lucas J Castro-Alves
No abstract text is available yet for this article.
September 9, 2018: Journal of Surgical Oncology
Florencio Quero-Valenzuela, Inmaculada Piedra-Fernández, Francisco Hernández-Escobar
No abstract text is available yet for this article.
September 9, 2018: Journal of Surgical Oncology
Reiko Tsukuura, Hayahito Sakai, Yuma Fuse, Takumi Yamamoto
No abstract text is available yet for this article.
September 5, 2018: Journal of Surgical Oncology
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