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Journal of Surgical Oncology

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https://www.readbyqxmd.com/read/29355996/lymphatic-vessel-diameter-in-female-pelvic-cancer-related-lower-extremity-lymphedematous-limbs
#1
Takumi Yamamoto, Mitsunaga Narushima, Isao Koshima
BACKGROUND: Lymphaticovenular anastomosis (LVA) has become one of the useful surgical treatments for compression-refractory lower extremity lymphedema (LEL). It is important to anastomose larger lymphatic vessels with abundant lymph flows in LVA surgery. This study aimed to clarify factors associated with lymphatic vessel diameter. METHODS: One hundred thirty-four LEL patients who underwent pre-operative indocyanine green (ICG) lymphography and LVA from June 2009 to August 2014 in a single institution were included in this retrospective observational study...
January 22, 2018: Journal of Surgical Oncology
https://www.readbyqxmd.com/read/29355987/staged-surgical-treatment-of-extremity-lymphedema-with-dual-gastroepiploic-vascularized-lymph-node-transfers-followed-by-suction-assisted-lipectomy-a-prospective-study
#2
Mouchammed Agko, Pedro Ciudad, Hung-Chi Chen
BACKGROUND: Both physiologic and excisional procedures have been described for the treatment of lymphedema. However, there exist few reports that combine these procedures. The objective of this study was to evaluate the effectiveness of combining vascularized lymph node transfer (VLNT) with suction-assisted lipectomy (SAL) in a staged manner for the treatment of extremity lymphedema. METHODS: Patients with unilateral late stage II lymphedema (International Society of Lymphology), who consented to staged surgical treatment, were evaluated prospectively...
January 22, 2018: Journal of Surgical Oncology
https://www.readbyqxmd.com/read/29355979/preoperative-coagulation-abnormalities-as-a-risk-factor-for-adverse-events-after-pancreas-surgery
#3
Joshua Castle, Aditya Mazmudar, David Bentrem
OBJECTIVE: To determine whether elevated INR or PTT values predicted 30-day postoperative adverse events following elective pancreatectomy. METHODS: The American college of surgeons national surgical quality improvement program (ACS-NSQIP) database was used to identify 14 747 patients undergoing elective pancreatectomy from 2005 to 2013. The association of elevated INR or PTT with 30-day postoperative outcomes of morbidity and mortality was examined using multivariate logistic regression analysis...
January 22, 2018: Journal of Surgical Oncology
https://www.readbyqxmd.com/read/29355977/helicobacter-pylori-infection-is-associated-with-favorable-outcome-in-advanced-gastric-cancer-patients-treated-with-s-1-adjuvant-chemotherapy
#4
Satoshi S Nishizuka, Gen Tamura, Masahiro Nakatochi, Norimasa Fukushima, Yukimi Ohmori, Chihiro Sumida, Takeshi Iwaya, Takashi Takahashi, Keisuke Koeda
BACKGROUND AND OBJECTIVES: Limited information exists regarding beneficial effects of Helicobacter pylori. To examine the effect in advanced gastric cancer, we compared survival for patients treated with surgery-only or adjuvant chemotherapy on the basis of H. pylori infection status. METHODS: A cohort of 491 patients who underwent R0 resection for locally advanced gastric cancer between 2000 and 2009 at 12 institutions in northern Japan was included. H. pylori infection status, was assessed from paraffin-embedded formalin-fixed samples...
January 22, 2018: Journal of Surgical Oncology
https://www.readbyqxmd.com/read/29355975/c-reactive-protein-as-a-marker-of-the-surgical-stress-reduction-within-an-eras-protocol-enhanced-recovery-after-surgery-in-colorectal-surgery-a-prospective-cohort-study
#5
Mercedes Cabellos Olivares, María Labalde Martínez, Miguel Torralba, José R Rodríguez Fraile, Juan C Atance Martínez
BACKGROUND: The aim of this study is to evaluate the effectiveness of an Enhanced Recovery After Surgery Protocol (ERAS) in relation to reduce the Systemic Inflammatory Response (SIR) to surgery using C-reactive protein (CRP) in the first (POD1), second (POD2) and third (POD3) postoperative day. METHODS: We enrolled 121 patients (ERAS group) that underwent elective colorectal surgery with ERAS, and compared them with 135 patients (preERAS group) that had undergone surgery prior to the implementation...
January 22, 2018: Journal of Surgical Oncology
https://www.readbyqxmd.com/read/29355970/comparison-of-open-and-closed-abdomen-techniques-for-the-delivery-of-intraperitoneal-pemetrexed-using-a-murine-model
#6
David Badrudin, Lucas Sideris, Camille Perrault-Mercier, Julien Hubert, François A Leblond, Pierre Dubé
BACKGROUND AND OBJECTIVES: Pemetrexed is an appealing agent to use for cytoreductive surgery with hyperthermic intraperitoneal chemotherapy (HIPEC). However, the optimal method of pemetrexed delivery still remains undefined. Using a murine model, we compared the use of open and closed abdomen techniques on the absorption of intraperitoneal (IP) pemetrexed in different compartments. METHODS: Eleven Sprague-Dawley rats were submitted to a fixed dose of IP pemetrexed (1000 mg/m2 ) at a perfusion temperature of 40°C during 25 min according to two techniques: open and closed...
January 22, 2018: Journal of Surgical Oncology
https://www.readbyqxmd.com/read/29355969/primary-liver-sarcomas-in-the-modern-era-resection-or-transplantation
#7
Ioannis T Konstantinidis, Carolijn Nota, Zeljka Jutric, Philip Ituarte, Warren Chow, Peiguo Chu, Gagandeep Singh, Susanne G Warner, Laleh G Melstrom, Yuman Fong
BACKGROUND AND OBJECTIVES: Primary liver sarcomas (PLS) are rare. Published series are limited by small numbers of patients. METHODS: We reviewed the National Cancer Database (2004-2014) for patients who underwent surgical resection of PLS. RESULTS: Of 237 patients identified, the majority were female (60.8%), with median age of 52 years. Histologies were: epithelioid hemangioendothelioma (n = 67), angiosarcoma (n = 64), leiomyosarcoma (n = 33), embryonal rhabdomyosarcoma (n = 31), carcinosarcoma (n = 16), giant cell sarcoma (n = 14), spindle cell sarcoma (n = 12)...
January 22, 2018: Journal of Surgical Oncology
https://www.readbyqxmd.com/read/29355966/predictors-for-30-day-readmission-after-pulmonary-resection-for-lung-cancer
#8
Florencio Quero-Valenzuela, Inmaculada Piedra-Fernández, María Martínez-Ceres, Pedro J Romero-Palacios, Abel Sánchez-Palencia, Antonio Cueto-Ladrón De Guevara, Pablo Torné-Poyatos
BACKGROUND: The purpose of this study was to assess the rate, cause, and factors associated with readmissions following pulmonary resection for lung cancer and their relationship with 90-day mortality. METHODS: A prospective cohort study was conducted of 379 patients who underwent surgery for lung cancer at the university hospitals Granada, Spain between 2012 and 2016. RESULTS: The rate of readmissions within 30 postoperative days was 6.2%...
January 22, 2018: Journal of Surgical Oncology
https://www.readbyqxmd.com/read/29355962/alternative-vascular-constructs-of-lymph-node-flap-transfer
#9
Fabio Nicoli, Georgios Orfaniotis, Pedro Ciudad, Kidakorn Kiranantawat, Davide Lazzeri, Michele Maruccia, Joannis Constantinides, Bulent Sacak, Ram M Chilgar, Ke Li, Yi Xin Zhang, Hung-Chi Chen
Vascularized lymph node transfer is a quite innovative physiological surgical procedure for the lymphedema treatment. Although is gaining more popularity due to its promising results, there are some concerns regarding difficult to harvest it and the potential risk of iatrogenic lymphedema. Here, we present alternative vascular constructs of lymph node flap for the treatment of lymphedema, which provide the benefits of a technically easier dissection and physiological reconstruction of the damaged lymphatics...
January 22, 2018: Journal of Surgical Oncology
https://www.readbyqxmd.com/read/29355959/optimized-thoracoport-design-for-the-thoracoscopic-procedure-during-minimally-invasive-esophagectomy
#10
Yunke Zhu, Xiaolong Zhang, Yang Hu, Lunxu Liu
Minimally invasive esophagectomy has several benefits as an effective alternative treatment for esophageal cancer. The three-phase esophageal resection may be the most popular approach to esophagectomy. Numerous thoracoport designs are available for the thoracoscopic procedure. The present study aims to contribute a distinctive three-port technique that is designed to minimize surgical trauma and facilitate operation during the thoracoscopic procedure. In this paper, we describe and demonstrate the details of the port design and each operation step...
January 22, 2018: Journal of Surgical Oncology
https://www.readbyqxmd.com/read/29346711/early-assessment-of-post-surgical-outcomes-with-pre-pectoral-breast-reconstruction-a-literature-review-and-meta-analysis
#11
Abhishek Chatterjee, Maurice Y Nahabedian, Allen Gabriel, David Macarios, Mousam Parekh, Fang Wang, Leah Griffin, Steven Sigalove
BACKGROUND: Pre-pectoral breast reconstruction is an emerging surgical approach. This study provides an early assessment of outcomes with the technique. METHODS: A comprehensive literature review was performed through searches of PubMed® /MEDLINE® to identify studies on pre-pectoral reconstruction. Patient characteristics and outcomes were extracted from studies and pooled. Linear relationships between complication rates and patient characteristics with pre-pectoral reconstruction were analyzed...
January 18, 2018: Journal of Surgical Oncology
https://www.readbyqxmd.com/read/29315649/current-principles-of-surgery-for-retroperitoneal-sarcomas
#12
REVIEW
Mark Fairweather, Ricardo J Gonzalez, Dirk Strauss, Chandrajit P Raut
Surgery for primary retroperitoneal sarcomas (RPS) often requires a technically challenging, en bloc multivisceral resection to optimize outcomes. Surgery may also be appropriate for patients with localized recurrent RPS. Anatomic considerations and tumor biology driven by histologic subtype may guide the extent of resection in patients with RPS. This review provides an overview of the current surgical principles for primary and recurrent RPS.
January 8, 2018: Journal of Surgical Oncology
https://www.readbyqxmd.com/read/29315604/trends-of-genetic-screening-in-patients-with-pheochromocytoma-and-paraganglioma-15-year-experience-in-a-high-volume-tertiary-referral-center
#13
Ammar Asban, Wouter P Kluijfhout, Frederick T Drake, Toni Beninato, Elizabeth Wang, Kate Chomsky-Higgins, Wen T Shen, Jessica E Gosnell, Insoo Suh, Quan-Yang Duh
BACKGROUND AND OBJECTIVES: Genetic testing for pheochromocytoma and paraganglioma allows for early detection of hereditary syndromes and enables close follow-up of high-risk patient. We investigated the trends in genetic testing among patients at a high-volume referral center and evaluated the prevalence of pheochromocytomas and paragangliomas. METHODS: We reviewed the charts of 129 patients who underwent adrenalectomy for pheochromocytoma and paraganglioma between January 2000 and July 2015...
January 8, 2018: Journal of Surgical Oncology
https://www.readbyqxmd.com/read/29315600/validation-of-clinical-prognostic-scores-for-patients-treated-with-curative-intent-for-recurrent-colorectal-liver-metastases
#14
Aurélien Dupré, Adeeb Rehman, Robert P Jones, Alex Parker, Rafael Diaz-Nieto, Stephen W Fenwick, Graeme J Poston, Hassan Z Malik
BACKGROUND: Scoring systems were developed to stratify patients with colorectal liver metastases considered for liver resection into different risk groups. Such scores have never been evaluated in recurrent liver metastases. The aim of this study was to evaluate whether these scores are applicable to patients with recurrent colorectal liver metastases and treated with curative intent. METHODS: We retrospectively analyzed data from 375 consecutive patients who underwent liver surgery for colorectal liver metastases between June 2010 and August 2015...
January 8, 2018: Journal of Surgical Oncology
https://www.readbyqxmd.com/read/29315595/mid-to-long-term-clinical-outcome-of-giant-cell-tumor-of-bone-treated-with-calcium-phosphate-cement-following-thorough-curettage-and-phenolization
#15
Akihiko Takeuchi, Prakrit Suwanpramote, Norio Yamamoto, Toshiharu Shirai, Katsuhiro Hayashi, Hiroaki Kimura, Shinji Miwa, Takashi Higuchi, Kensaku Abe, Hiroyuki Tsuchiya
BACKGROUND AND OBJECTIVES: Giant cell tumors of bone (GCTB) are intermediate and locally aggressive bone tumor. Calcium phosphate cement (CPC) is a bone void filler used in orthopaedic surgery. This study investigated the clinical outcome of GCTB treated with thorough curettage, phenolization, and CPC. METHODS: We investigated 26 patients with at least 36 months of follow-up. The mean age and follow-up were 37 years (range: 19-63) and 87 months (range: 38-169), respectively...
January 8, 2018: Journal of Surgical Oncology
https://www.readbyqxmd.com/read/29315584/evaluation-of-extended-antibiotic-prophylaxis-in-patients-undergoing-indicated-non-cosmetic-panniculectomy-at-the-time-of-gynecologic-surgery
#16
Jay R Patibandla, Christina N Kufel, Michael P Hopkins
BACKGROUND: Panniculectomy at time of gynecologic surgery is used to improve visualization and prevent major complications in morbidly obese patients. We examine the role of extended antibiotic prophylaxis in prevention of surgical site infections (SSI), specifically based on patient risk factors (hypertension, diabetes, smoking). METHODS: A prospective cohort study of all women who underwent panniculectomy at the time of gynecologic surgery from September 2014 to March 2016 at a university-affiliated hospital...
January 8, 2018: Journal of Surgical Oncology
https://www.readbyqxmd.com/read/29314041/surgical-morbidity-in-retroperitoneal-sarcoma-resection
#17
Andrea J MacNeill, Marco Fiore
Resection of retroperitoneal sarcoma (RPS) typically involves multivisceral resection. The morbidity of RPS resection has decreased over time despite widespread adoption of radical resection. Certain patterns of resection are associated with higher complication rates and elderly patients are at increased risk of morbidity. Administration of preoperative radiotherapy does not increase morbidity, but intraoperative and brachytherapy techniques are associated with heightened toxicities. Long-term functional outcomes and quality of life scores after RPS resection are acceptable...
January 3, 2018: Journal of Surgical Oncology
https://www.readbyqxmd.com/read/29284076/percutaneous-hepatic-perfusion-with-melphalan-in-uveal-melanoma-a-safe-and-effective-treatment-modality-in-an-orphan-disease
#18
Ioannis Karydis, Alexandra Gangi, Matthew J Wheater, Junsung Choi, Iain Wilson, Kerry Thomas, Neil Pearce, Arjun Takhar, Sanjay Gupta, Danielle Hardman, Sean Sileno, Brian Stedman, Jonathan S Zager, Christian Ottensmeier
BACKGROUND: Metastatic uveal melanoma (UM) carries a poor prognosis; liver is the most frequent and often solitary site of recurrence. Available systemic treatments have not improved outcomes. Melphalan percutaneous hepatic perfusion (M-PHP) allows selective intrahepatic delivery of high dose cytotoxic chemotherapy. METHODS: Retrospective analysis of outcomes data of UM patients receiving M-PHP at two institutions was performed. Tumor response and toxicity were evaluated using RECIST 1...
December 28, 2017: Journal of Surgical Oncology
https://www.readbyqxmd.com/read/29284072/adjuvant-therapy-is-associated-with-improved-survival-after-curative-resection-for-hilar-cholangiocarcinoma-a-multi-institution-analysis-from-the-u-s-extrahepatic-biliary-malignancy-consortium
#19
Bradley A Krasnick, Linda X Jin, Jesse T Davidson, Dominic E Sanford, Cecilia G Ethun, Timothy M Pawlik, George A Poultsides, Thuy Tran, Kamran Idrees, William G Hawkins, William C Chapman, Maria B M Doyle, Sharon M Weber, Steven M Strasberg, Ahmed Salem, Robert C G Martin, Chelsea A Isom, Charles Scoggins, Carl R Schmidt, Perry Shen, Eliza Beal, Ioannis Hatzaras, Rivfka Shenoy, Shishir K Maithel, Ryan C Fields
BACKGROUND: Curative-intent treatment for localized hilar cholangiocarcinoma (HC) requires surgical resection. However, the effect of adjuvant therapy (AT) on survival is unclear. We analyzed the impact of AT on overall (OS) and recurrence free survival (RFS) in patients undergoing curative resection. METHODS: We reviewed patients with resected HC between 2000 and 2015 from the ten institutions participating in the U.S. Extrahepatic Biliary Malignancy Consortium...
December 28, 2017: Journal of Surgical Oncology
https://www.readbyqxmd.com/read/29284070/evaluation-of-fluorescence-guided-surgery-agents-in-a-murine-model-of-soft-tissue-fibrosarcoma
#20
Andrew C Prince, Andrew S McGee, Herrick Siegel, Eben L Rosenthal, Nicole K Behnke, Jason M Warram
BACKGROUND AND OBJECTIVES: Soft tissue sarcomas (STS) are mesenchymal malignancies. Treatment mainstay is surgical resection with negative margins ± adjuvant treatment. Fluorescence-guided surgical (FGS) resection can delineate intraoperative margins; FGS has improved oncologic outcomes in other malignancies. This novel strategy may minimize resection-associated morbidity while improving local tumor control. METHODS: We evaluate the tumor-targeting specificity and utility of fluorescence-imaging agents to provide disease-specific contrast...
December 28, 2017: Journal of Surgical Oncology
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