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Journal of Surgical Oncology

Nadia Haj Mohammad, Sophia De Rooij, Maarten Hulshof, Jelle Ruurda, Bas Wijnhoven, Frans Erdkamp, Meindert Sosef, Suzanne Gisbertz, Mark van Berge Henegouwen, Mirjam Sprangers, Hanneke van Laarhoven
BACKGROUND AND OBJECTIVES: Neoadjuvant chemoradiation (nCRT) followed by esophagectomy is a treatment with curative intent for resectable esophageal cancer. The aim of this study was to measure activities of daily living (ADL) and quality of life (QoL), and to examine correlates of changes in ADL and QoL. METHODS: A prospective study was performed with three time points (baseline, 1 week after the end of nCRT, 3-months post-surgery) together with a cross-sectional post-treatment study...
October 20, 2016: Journal of Surgical Oncology
Yalan Bi, Yinghui Deng, Shanqing Li, Xiaoyun Zhou, Yeye Chen, Dongjie Ma, Xinxin Mao, Yuzhou Guan, Jie Chen, Yunxiao Meng
OBJECTIVES: To investigate the immunoreactivity of TTF-1 and PAX8 in neuroendocrine carcinoma of thymic (TNEC) and pulmonary origins (PNEC), and whether their immunophenotyping could be used to distinguish between NEC of the two sites, as well as prognosis of patients with TNEC. METHODS: Twenty-two cases of TNEC and 20 cases of PNEC were selected for immunohistochemical analysis using PAX8 and TTF-1. Clinical data and follow-up information were obtained for survival analyses...
October 20, 2016: Journal of Surgical Oncology
Shih-Ping Cheng, Po-Sheng Yang, Ming-Nan Chien, Ming-Jen Chen, Jie-Jen Lee, Chien-Liang Liu
BACKGROUND AND OBJECTIVES: The induction of tumor-associated carbohydrate antigen results from altered glycosylation in transformed cells. Globo H is a hexasaccharide glycosphingolipid overexpressed on malignancies of epithelial origin and has become an attractive vaccine target. We aimed to investigate the expression patterns and prognostic value of Globo H in thyroid neoplasms. METHODS: Globo H expression was examined by immunohistochemical analysis using commercial and in-house tissue microarrays...
October 18, 2016: Journal of Surgical Oncology
Jan Grendar, Elijah Dixon
No abstract text is available yet for this article.
October 18, 2016: Journal of Surgical Oncology
Ioannis Christakis, Angelica M Silva, Lily Joy Kwatampora, Carla L Warneke, Callisia N Clarke, Michelle D Williams, Elizabeth G Grubbs, Jeffrey E Lee, Naifa L Busaidy, Nancy D Perrier
BACKGROUND AND OBJECTIVES: Parathyroid carcinoma (PC) is rare but potentially lethal. No standardized staging system or treatment guidelines have been established. We aimed to determine whether management of PC and patient outcomes have changed at our institution over the past 35 years. METHODS: Retrospective review of patients with PC at our institution between 1980 and 2015. Patients were grouped by date of initial surgery: group 1, 1980-2001; group 2, 2002-2015...
October 18, 2016: Journal of Surgical Oncology
Le Xiao, Jian-Wei Li, Shu-Guo Zheng
BACKGROUND: The reported protocol was difficult to expose the hepatic veins for laparoscopic anatomical hepatectomy of segments VII and VIII. We introduce a new, convenient, applicable approach with the hepatic vein exposed from the head side. METHODS: This study included 10 patients who underwent laparoscopic liver resection for HCC in the segments VII and VIII between October, 2014 and November, 2015. Their perioperative course and operative techniques were retrospectively evaluated...
October 14, 2016: Journal of Surgical Oncology
Jeffrey D Robinson, Maria Venetis, Richard L Street, Thomas Kearney
BACKGROUND: Despite data on breast cancer patients' information needs and their association with patient outcomes, there are currently no data on what U.S. patients actually ask surgeons during primary consultations. METHODS: Working from transcripts of videotaped, treatment decision making consultations between breast cancer patients and surgeons, we identify all questions (by patients and companions) and then use grounded theory techniques to determine the most recurrent question-asking themes...
October 12, 2016: Journal of Surgical Oncology
Bertram Yuh
No abstract text is available yet for this article.
October 10, 2016: Journal of Surgical Oncology
Meritxell Valls-Mateus, Alexis Ortega, José Luis Blanch, Francesc Sabater, Manuel Bernal-Sprekelsen, Isabel Vilaseca
BACKGROUND AND OBJECTIVES: Previous studies showed good short-term Quality of life (QOL) after Transoral Laser Microsurgery (TLM) for laryngeal cancer. Here, we aimed to evaluate QOL after TLM in the long-term. METHODS: Prospective longitudinal study. Sixty-two consecutive disease-free patients were evaluated using UW-QOL v4 and SF-12 questionnaires, 1 and 5 years after TLM. Changes over time were assessed according to age, location, and tumor size. Long-term VHI-10 was also evaluated...
October 6, 2016: Journal of Surgical Oncology
Amine Souadka, Mohammed Anass Majbar, Mohamed Raiss
No abstract text is available yet for this article.
October 6, 2016: Journal of Surgical Oncology
Jin Cheon Kim
No abstract text is available yet for this article.
October 6, 2016: Journal of Surgical Oncology
Satoshi Onoda, Yoshihiro Kimata, Kiyoshi Yamada, Noriko Seki, Yuji Hiramatsu
PURPOSE: This study evaluated the relationships of the size and number of superficial groin lymph nodes with the lower limb lymphedema stage and thus examined the role of superficial lymphatic lymph nodes in secondary lymphedema development. METHODS: We determined the number and size of superficial groin lymph nodes using horizontal plane computed tomography (CT) and the lymphedema stage in the lower limbs of 25 patients with gynecologic cancer. RESULTS: The patients had an average of 2...
October 6, 2016: Journal of Surgical Oncology
Ting-Shi Su, Ping Liang, Huan-Zhen Lu, Jian Liang, Ying-Chuan Gao, Ying Zhou, Yong Huang, Min-Yang Tang, Jian-Ning Liang
No abstract text is available yet for this article.
October 4, 2016: Journal of Surgical Oncology
Yukihiko Hiroshima, Thinzar M Lwin, Takashi Murakami, Ali A Mawy, Tanaka Kuniya, Takashi Chishima, Itaru Endo, Bryan M Clary, Robert M Hoffman, Michael Bouvet
BACKGROUND AND OBJECTIVES: Delineation of adequate tumor margins is critical in oncologic surgery, particularly in resection of metastatic lesions. Surgeons are limited in visualization with bright-light surgery, but fluorescence-guided surgery (FGS) has been efficacious in helping the surgeon achieve negative margins. METHODS: The present study uses FGS in a mouse model that has undergone surgical orthotopic implantation (SOI) of colorectal liver metastasis tagged with green fluorescent protein (GFP)...
October 3, 2016: Journal of Surgical Oncology
Claudia Deckers, Bart H W Schreuder, Gerjon Hannink, Jacky W J de Rooy, Ingrid C M van der Geest
BACKGROUND AND OBJECTIVES: Both enchondroma and atypical cartilaginous tumors (ACT) are not considered malignant, so inactive and asymptomatic tumors might not need surgery. To the best of our knowledge, this is the first study that has been done to evaluate the natural course of conservative-treated enchondroma and ACT in the long bones. METHODS: For this retrospective study, we analyzed the results of patients in whom we refrained from surgery and only regularly performed radiological follow-up of the tumor...
October 3, 2016: Journal of Surgical Oncology
Anne Helene Køstner, Christian Kersten, Thyra Löwenmark, Karin A Ydsten, Reetta Peltonen, Helena Isoniemi, Caj Haglund, Ulf Gunnarsson, Bengt Isaksson
BACKGROUND AND OBJECTIVES: Systemic inflammation has been associated with poor survival in several tumor types, but has been less extensively studied in resectable metastatic disease. The aim of the present study was to evaluate the prognostic role of CRP in colorectal cancer patients with liver metastases (CRLM) compared to conventional tumor- and patient-related clinicopathological features as well as other indicators of the systemic inflammatory response (SIR). METHODS: A multinational retrospective study of 492 CRLM patients undergoing potentially curative resection of liver metastases between 1999 and 2009...
October 3, 2016: Journal of Surgical Oncology
Megan Winner, Ana Wilson, Alexander Yahanda, Yuhree Kim, Timothy M Pawlik
BACKGROUND AND OBJECTIVE: Patients with advanced cancer often misperceive the purpose and likely effectiveness of cancer treatments. The aim of this study was to characterize patient and provider perceptions in the setting of surgery for potentially curable cancer. METHODS: One hundred and six patient-surgeon dyads were surveyed about their expectations for upcoming surgery. Items scored using a Likert scale were compared using the Wilcoxon signed-rank test. RESULTS: Patients and surgeons reported excellent communication and shared decision-making...
October 3, 2016: Journal of Surgical Oncology
Daisuke Hokuto, Takeo Nomi, Ichiro Yamato, Satoshi Yasuda, Shinsaku Obara, Takahiro Yoshikawa, Chihiro Kawaguchi, Takatsugu Yamada, Hiromichi Kanehiro, Yoshiyuki Nakajima
BACKGROUND AND OBJECTIVES: The impact of perioperative chemotherapy on patients with multiple colorectal liver metastases (CRLM) remains unclear. We attempted to examine whether the introduction of modern chemotherapies has improved the prognosis of patients that undergo liver resection for ≥4 CRLM. METHODS: Between January 1990 and December 2013, 194 patients underwent liver resection for CRLM at our institution. The outcomes of the patients with ≥4 and 1-3 CRLM were compared before and after 2005, when modern chemotherapies were introduced to Japan...
September 28, 2016: Journal of Surgical Oncology
Peng Zhang, Rui Deng, Ke Liu, Xiao-Ming Shuai, Jie Bai, Wei-Long Chang, Jin-Bo Gao, Kai-Lin Cai, Guo-Bin Wang, Kai-Xiong Tao
OBJECTIVES: To investigate gastrointestinal stromal tumor (GIST) clinicopathologic characteristics in young adults. METHODS: Clinicopathologic data from GIST patients under 35 years diagnosed at our hospital from January 2005 to December 2014 were retrospectively collected. RESULTS: Thirty-one (5.3%, 31/585) patients were included; 17 (54.8%) were female. The most common presentation and primary tumor site were gastrointestinal bleeding (n = 18, 58...
September 23, 2016: Journal of Surgical Oncology
Kazuya Kato, Yoshiaki Iwasaki, Kazuhiko Onodera, Mineko Higuchi, Kimitaka Kato, Yurina Kato, Minoru Matsuda, Seiya Endo, Yuko Kobashi, Masahiko Taniguchi
BACKGROUND AND PURPOSE: We aimed to determine the success rate and any complications using a percutaneous approach to the femoral vein (FV) for placement of a totally implantable access port (TIVAP), with a preoperative assessment of the femoral and iliac veins using computed tomography-venography (CT-V). METHODS: A prospective study of 72 patients was conducted where placement of a TIVAP was attempted via the right FV, with the port placed in the anterior thigh, when subclavian vein or jugular vein access was contraindicated...
September 22, 2016: Journal of Surgical Oncology
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