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Journal of Sexual Medicine

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https://www.readbyqxmd.com/read/28089244/synchronous-ipsilateral-high-submuscular-placement-of-prosthetic-balloons-and-reservoirs
#1
Nicholas L Kavoussi, Matthias D Hofer, Boyd R Viers, Billy H Cordon, Ryan P Mooney, Travis J Pagliara, Jeremy M Scott, Allen F Morey
INTRODUCTION: Synchronous ipsilateral high submuscular placement of artificial urinary sphincter (AUS) pressure-regulating balloons (PRBs) and inflatable penile prosthesis (IPP) reservoirs in a single submuscular tunnel is a novel strategy that could be advantageous for patients who have had major pelvic surgery. AIM: To report our initial experience with synchronous ipsilateral vs bilateral placement of AUS PRBs and IPP reservoirs in men undergoing implant surgery...
January 11, 2017: Journal of Sexual Medicine
https://www.readbyqxmd.com/read/28087357/early-effect-of-bariatric-surgery-on-urogenital-function-in-morbidly-obese-men
#2
Maha Aleid, Asif Muneer, Sara Renshaw, Jason George, Andrew D Jenkinson, Marco Adamo, Mohamed Elkalaawy, Rachel Batterham, David J Ralph, Majid Hashemi, Selim Cellek
INTRODUCTION: Obesity is an independent risk factor for erectile dysfunction (ED) and lower urinary tract symptoms (LUTS). Bariatric surgery has been shown to improve erectile function and urinary symptoms in medium- to long-term studies (3- to 12-month postoperative follow-up). AIM: To investigate the early effect (1 month postoperatively) of bariatric surgery on ED and LUTS, which has not previously been investigated. METHODS: Morbidly obese men (body mass index > 35 kg/m(2)) undergoing bariatric surgery were asked to complete the International Index of Erectile Function (IIEF) and International Prostate Symptom Score (IPSS) questionnaires before surgery and 1, 3, and 6 months after surgery...
January 10, 2017: Journal of Sexual Medicine
https://www.readbyqxmd.com/read/28087356/long-term-sensitivity-and-patient-reported-functionality-of-the-neoclitoris-after-gender-reassignment-surgery
#3
Hannes Sigurjónsson, Caroline Möllermark, Johan Rinder, Filip Farnebo, T Kalle Lundgren
INTRODUCTION: A cornerstone of treating gender dysphoria for transgender women is gender reassignment surgery (GRS) encompassing vaginoplasty and clitoroplasty. The neoclitoris is harvested as a flap with a neurovascular pedicle from the proximal dorsal part of the glans penis. Few long-term follow-ups exist on postoperative sensation and patient-reported sexual functionality of the neoclitoris. AIM: To examine the sensitivity of the neoclitoris and its relation to orgasm and sexual function at least 1 year after GRS...
January 10, 2017: Journal of Sexual Medicine
https://www.readbyqxmd.com/read/28041844/is-pelvic-floor-dysfunction-an-independent-threat-to-sexual-function-a-cross-sectional-study-in-women-with-pelvic-floor-dysfunction
#4
Ryan J Li-Yun-Fong, Maryse Larouche, Momoe Hyakutake, Nicole Koenig, Catherine Lovatt, Roxana Geoffrion, Lori A Brotto, Terry Lee, Geoffrey W Cundiff
INTRODUCTION: Prior studies have reported an association of sexual dysfunction with pelvic floor dysfunction (PFD), but without defining causation. AIM: To investigate predictors of sexual function in women with PFD, including pelvic organ prolapse, stress urinary incontinence, overactive bladder, obstructed defecation, and fecal incontinence. METHODS: This retrospective cross-sectional study included 755 women (mean age = 56 years, 68% postmenopausal) referred for PFD (2008-2013)...
December 29, 2016: Journal of Sexual Medicine
https://www.readbyqxmd.com/read/27989490/paraphilic-sexual-offenders-do-not-differ-from-control-subjects-with-respect-to-dopamine-and-serotonin-related-genetic-polymorphisms
#5
Andrzej Jakubczyk, Aleksandra Krasowska, Marcin Bugaj, Maciej Kopera, Anna Klimkiewicz, Agata Łoczewska, Aneta Michalska, Aleksandra Majewska, Natalia Szejko, Anna Podgórska, Małgorzata Sołowiej, Leszek Markuszewski, Sławomir Jakima, Rafał Płoski, Kirk Brower, Marcin Wojnar
INTRODUCTION: Rape and pedophilic child molestation are the most commonly convicted sexual offenses in Poland. Recent studies have suggested a possible genetic contribution toward pathologic sexual interests and behaviors. AIM: To analyze and compare functional polymorphisms of genes associated with the activity of the serotonin and dopamine systems in a group of paraphilic sexual offenders and control subjects. METHODS: The study sample (n = 97) consisted of two groups: paraphilic sexual offenders (65 pedophilic child molesters and 32 rapists) and controls (n = 76)...
December 15, 2016: Journal of Sexual Medicine
https://www.readbyqxmd.com/read/27989489/testosterone-pellet-implantation-practices-a-sexual-medicine-society-of-north-america-smsna-member-questionnaire
#6
Michael J Piecuch, Brijesh G Patel, Lawrence Hakim, Run Wang, Hossein Sadeghi-Nejad
INTRODUCTION: There has been renewed interest in the use of subcutaneous testosterone pellets for the treatment of hypogonadism since the introduction of Testopel in 2008 by Slate Pharmaceuticals (Durham, NC, USA). Manufacturer guidelines recommend using two to six pellets; however, in the clinical setting, this is deemed insufficient. This has produced a wide variety of testosterone pellet usage that is not fully understood. AIM: To better understand subcutaneous testosterone pellet implantation practices among members of the Sexual Medicine Society of North America (SMSNA)...
December 15, 2016: Journal of Sexual Medicine
https://www.readbyqxmd.com/read/27989488/considering-attachment-and-partner-perceptions-in-the-prediction-of-physical-and-emotional-sexual-satisfaction
#7
Camilla S Øverup, C Veronica Smith
INTRODUCTION: Attachment theory provides a framework for understanding sexual satisfaction; in general, research suggests that attachment anxiety and avoidance are associated with decreased sexual satisfaction. Given their different working models of self and other, perceptions of the partner's level of satisfaction might differentially influence people's own perceptions of satisfaction based on their attachment avoidance and anxiety. AIM: To examine the predictive value of attachment anxiety and avoidance and perceptions of partner satisfaction in predicting physical and emotional satisfaction after sexual interactions in two studies...
December 15, 2016: Journal of Sexual Medicine
https://www.readbyqxmd.com/read/27989487/effect-of-bkca-channel-opener-ldd175-on-erectile-function-in-an-in%C3%A2-vivo-diabetic-rat-model
#8
Hyun Hwan Sung, Su Jeong Kang, Mee Ree Chae, Hye Kyung Kim, Jong Kwan Park, Chul Young Kim, Sung Won Lee
INTRODUCTION: The development of novel therapeutic options is imperative in patients with erectile dysfunction, especially those non-responsive to phosphodiesterase type 5 inhibitors. LDD175, a potent BKCa channel opener, has a relaxation effect on the in vitro cavernosal smooth muscle strip. AIM: To investigate the effect of LDD175 on erectile function using in vivo animal disease model. METHODS: Male Sprague-Dawley rats were assigned to a normal control group and seven diabetic groups: diabetic control, sildenafil (1 and 5 mg/kg), LDD175 (5 and 10 mg/kg), LDD175 5 mg/kg plus sildenafil 1 mg/kg, and LDD175 10 mg/kg plus tetraethylammonium...
December 15, 2016: Journal of Sexual Medicine
https://www.readbyqxmd.com/read/27986492/effects-of-low-intensity-extracorporeal-shockwave-therapy-on-erectile-dysfunction-a-systematic-review-and-meta-analysis
#9
REVIEW
Raul I Clavijo, Taylor P Kohn, Jaden R Kohn, Ranjith Ramasamy
INTRODUCTION: Low-intensity extracorporeal shock wave therapy (Li-ESWT) has been proposed as an effective non-invasive treatment option for erectile dysfunction (ED). AIM: To use systematic review and meta-analysis to assess the efficacy of Li-ESWT by comparing change in erectile function as assessed by the erectile function domain of the International Index of Erectile Function (IIEF-EF) in men undergoing Li-ESWT vs sham therapy for the treatment of ED. METHODS: Systematic search was conducted of MEDLINE, EMBASE, and ClinicalTrials...
December 13, 2016: Journal of Sexual Medicine
https://www.readbyqxmd.com/read/27939338/clinical-characteristics-health-care-utilization-and-costs-among-men-with-primary-or-secondary-hypogonadism-in-a-us-commercially-insured-population
#10
Michael Grabner, Amit Bodhani, Nikhil Khandelwal, Swetha Palli, Nicole Bonine, Mohit Khera
INTRODUCTION: Hypogonadism is broadly associated with increases in chronic comorbid conditions and health care costs. Little is known about the specific impact of primary and secondary hypogonadism on health care costs. AIM: To characterize the health care cost and utilization burden of primary and secondary hypogonadism in a population of US men with commercial insurance. METHODS: Newly diagnosed patients with International Classification of Diseases, Ninth Revision, Clinical Modification codes associated with specific medical conditions known to have a high prevalence of testosterone deficiency (ie, relating to primary or secondary hypogonadism) or who had fills for testosterone replacement therapy from January 1, 2007 through April 30, 2013 were identified in administrative claims data from the HealthCore Integrated Research Database...
December 8, 2016: Journal of Sexual Medicine
https://www.readbyqxmd.com/read/27938992/sexual-sensation-seeking-sexual-compulsivity-and-gender-identity-and-its-relationship-with-sexual-functioning-in-a-population-sample-of-men-and-women
#11
Andrea Burri
INTRODUCTION: Despite awareness of the importance of psycho-affective factors in the development of sexual problems, there is a lack of studies exploring the relation of sexual sensation seeking (SSS) and sexual compulsivity (SC) to sexual functioning. Because sex differences in SSS and SC have been reported, gender identity (GI; an individual's own experience of his or her gender that is unrelated to the actual biological sex) might act as a moderator in this relation. AIM: To understand the role of SSS and SC for men and women's sexual functioning and to explore whether these potential associations are moderated by GI...
December 6, 2016: Journal of Sexual Medicine
https://www.readbyqxmd.com/read/27938991/successful-placement-of-penile-prostheses-in-men-with-severe-corporal-fibrosis-following-vacuum-therapy-protocol
#12
Peter N Tsambarlis, Fahad Chaus, Laurence A Levine
INTRODUCTION: Penile prosthesis (PP) implantation in men with severe corporal fibrosis presents a significant surgical challenge. For the past 7 years, we have used a novel, preoperative protocol of daily vacuum therapy (VT) using a vacuum erection device for at least 3 months before PP placement for men with severe corporal fibrosis from PP infection or ischemic priapism. AIM: To evaluate this standardized preoperative regimen. METHODS: We retrospectively reviewed all patients who underwent three-piece PP placement at our institution from 2008 through 2015...
December 6, 2016: Journal of Sexual Medicine
https://www.readbyqxmd.com/read/27938990/effect-of-low-energy-linear-shockwave-therapy-on-erectile-dysfunction-a-double-blinded-sham-controlled-randomized-clinical%C3%A2-trial
#13
Grzegorz L Fojecki, Stefan Tiessen, Palle J S Osther
INTRODUCTION: Previous studies have shown that focal low-energy extracorporeal shockwave therapy (Li-ESWT) can have a positive effect in men with erectile dysfunction (ED). Linear Li-ESWT (LLi-ESWT) for ED has not been previously assessed in a randomized trial. AIM: To evaluate the treatment outcome of LLi-ESWT for ED. METHODS: Men with ED (n = 126) and a score lower than 25 points on the International Index of Erectile Function erectile function domain (IIEF-EF) were included...
December 6, 2016: Journal of Sexual Medicine
https://www.readbyqxmd.com/read/28065363/relationship-between-amyloid-precursor-protein-in-seminal-plasma-and-abnormal-penile-sympathetic-skin-response-in-lifelong-premature-ejaculation
#14
Zhiwei Hong, Yuming Feng, Hualong Ding, Xuechun Hu, Jin-Chun Lu, Xie Ge, Yifeng Ge, Bing Yao
INTRODUCTION: Hyperactivity of the sympathetic nervous system can play an important role in lifelong premature ejaculation (PE). Our previous study found that amyloid precursor protein (APP) levels in seminal plasma of patients with PE were clearly increased. Amyloid-β (Aβ) is derived from APP. Excessive Aβ, especially Aβ42, can cause neuronal dysfunction. AIM: To determine whether APP and Aβ42 are associated with an abnormal penile sympathetic skin response (PSSR)...
January 2017: Journal of Sexual Medicine
https://www.readbyqxmd.com/read/28065362/response-to-editorial-comment-profiles-of-cyberpornography-use-and-sexual-well-being-in-adults
#15
Marie-Pier Vaillancourt-Morel, Sarah Blais-Lecours, Chloé Labadie, Sophie Bergeron, Stéphane Sabourin, Natacha Godbout
No abstract text is available yet for this article.
January 2017: Journal of Sexual Medicine
https://www.readbyqxmd.com/read/28065361/editorial-comment-on-profiles-of-cyberpornography-use-and-sexual-well-being-in-adults
#16
Patricia D M Pascoal
No abstract text is available yet for this article.
January 2017: Journal of Sexual Medicine
https://www.readbyqxmd.com/read/28065360/intracavernous-injection-of-human-umbilical-cord-blood-mononuclear-cells-improves-erectile-dysfunction-in-streptozotocin-induced-diabetic-rats
#17
Tugba Cengiz, Ecem Kaya, Didem Yilmaz Oral, Isil Ozakca, Nur Bayatli, Arzu Zeynep Karabay, Tugba Altun Ensari, Tuna Karahan, Enis Yilmaz, Serap Gur
INTRODUCTION: Erectile dysfunction (ED) worsens in men with diabetes. Human umbilical cord blood (HUCB), because of its widespread availability and low immunogenicity, is a valuable source for stem cell-based therapies. AIM: To determine the effect of intracavernous injection of HUCB mononuclear cells (MNCs) on ED in rats with diabetes induced by streptozotocin. METHODS: Thirty adult male Sprague-Dawley rats were equally divided into three groups: (i) control, (ii) diabetes induced by streptozotocin (35 mg/kg intravenously for 8 weeks), and (iii) diabetic rats treated with MNCs (1 × 10(6) cells by intracavernosal injection)...
January 2017: Journal of Sexual Medicine
https://www.readbyqxmd.com/read/28065359/role-of-nanotechnology-in-erectile-dysfunction-treatment
#18
REVIEW
Alice Y Wang, Carol A Podlasek
INTRODUCTION: The biological importance of nanotechnology-based delivery vehicles for in vivo tissue regeneration is gaining acceptance by the medical community; however, its relevance and incorporation into the treatment of sexual dysfunction are evolving and have not been well evaluated. AIM: To provide scientific evidence examining the use of state-of-the-art nanotechnology-based delivery methodology in the treatment of erectile dysfunction (ED) in animal models and in patients...
January 2017: Journal of Sexual Medicine
https://www.readbyqxmd.com/read/28065358/standards-for-clinical-trials-in-male-and-female-sexual-dysfunction-iii-%C3%A2-unique-aspects-of-clinical-trials-in-male-sexual-dysfunction
#19
William A Fisher, Ilan Gruenwald, Emmanuele A Jannini, Ahinoam Lev-Sagie, Lior Lowenstein, Robert E Pyke, Yakov Reisman, Dennis A Revicki, Eusebio Rubio-Aurioles
This series of articles, Standards for Clinical Trials in Male and Female Sexual Dysfunction, began with the discussion of a common expected standard for clinical trial design in male and female sexual dysfunction, a common rationale for the design of phase I to IV clinical trials, and common considerations for the selection of study population and study duration in male and female sexual dysfunction. The second article in this series discussed fundamental principles in development, validation, and selection of patient- (and partner-) reported outcome assessment...
January 2017: Journal of Sexual Medicine
https://www.readbyqxmd.com/read/28065357/standards-for-clinical-trials-in-male-and-female-sexual-dysfunction-iv-unique-aspects-of-clinical-trials-in-female-sexual-dysfunction
#20
William A Fisher, Ilan Gruenwald, Emmanuele A Jannini, Ahinoam Lev-Sagie, Lior Lowenstein, Robert E Pyke, Yakov Reisman, Dennis A Revicki, Eusebio Rubio-Aurioles
The focus of this article, the fourth in the series, Standards for Clinical Trials in Male and Female Sexual Dysfunction, is on aspects of clinical trial design and measurement that are specific to clinical trials for treatments of female sexual dysfunction. Challenges in this area include the limited extent of treatment development and clinical trial research across the spectrum of female sexual dysfunctions, changing regulatory considerations, changing diagnostic criteria for female sexual dysfunction, and the need to articulate assessment procedures to these changes...
January 2017: Journal of Sexual Medicine
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