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Journal of Pediatric Gastroenterology and Nutrition

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https://www.readbyqxmd.com/read/28644370/adaptation-of-new-colombian-food-based-complementary-feeding-recommendations-using-linear-programming
#1
Marion Tharrey, Gilma A Olaya, Mary Fewtrell, Elaine Ferguson
OBJECTIVE: To use Linear Programming (LP) analyses to adapt New Complementary Feeding Guidelines (NCFg) designed for infants aged 6-12 month (m) living in poor socioeconomic circumstances in Bogota to ensure dietary adequacy for young children aged 12-23 m. DESIGN: A secondary data analysis was performed using dietary and anthropometric data collected from 12 m old infants (n = 72) participating in a randomised controlled trial. LP analyses were performed to identify nutrients whose requirements were difficult to achieve using local foods as consumed; and to test and compare the NCFg and alternative food-based recommendations (FBRs) on the basis of dietary adequacy, for 11 micronutrients, at the population level...
June 21, 2017: Journal of Pediatric Gastroenterology and Nutrition
https://www.readbyqxmd.com/read/28644369/european-society-for-pediatric-gastroenterology-hepatology-and-nutrition-s-educational-offer-and-the-training-syllabus
#2
Marco Maglione, Daniela Finizio, Gabor Veres, Tudor Lucian Pop, Grazia Isabella Continisio, Alexandra Papadopoulou, Alfredo Guarino
The basic knowledge necessary for a European pediatric gastroenterologist/hepatologist/nutritionist (PGHN) is set-out in the Training Syllabus (TS) of the European Society for Pediatric Gastroenterology, Hepatology, and Nutrition (ESPGHAN).We retrospectively compared the topics covered in ESPGHAN's training events between 2013 and 2016 with the basic knowledge TS items.Thirty-six initiatives including e-learning were identified. Twelve (33%) courses focused on gastroenterology, 9 (25%) on hepatology, and 10 (28%) on nutrition...
June 21, 2017: Journal of Pediatric Gastroenterology and Nutrition
https://www.readbyqxmd.com/read/28644368/vitamin-d-deficiency-is-not-associated-with-growth-or-the-incidence-of-common-morbidities-among-tanzanian-infants
#3
Christopher R Sudfeld, Karim P Manji, Emily R Smith, Said Aboud, Rodrick Kisenge, Wafaie W Fawzi, Christopher P Duggan
OBJECTIVE: The objective of this study was to examine risk factors for vitamin D deficiency and determine the association of vitamin D status with child growth and incidence of common morbidities among Tanzanian infants. METHODS: A prospective cohort of 581 Tanzanian infants born to HIV-uninfected mothers had serum 25-hydroxyvitamin D (25(OH)D) assessed at 6 weeks and 6 months of age. Infants were seen at monthly clinic visits for growth monitoring until 18 months of age...
June 21, 2017: Journal of Pediatric Gastroenterology and Nutrition
https://www.readbyqxmd.com/read/28644367/oral-cholic-acid-is-efficacious-and-well-tolerated-in-patients-with-bile-acid-synthesis-and-zellweger-spectrum-disorders
#4
James E Heubi, Kevin E Bove, Kenneth D R Setchell
BACKGROUND/AIMS: Patients with bile acid synthesis disorders (BASD) due to single enzyme defects (SED) or Zellweger spectrum disorders (ZSD) accumulate hepatotoxic atypical bile acids resulting in potentially fatal progressive liver disease. We evaluated the efficacy and safety of oral cholic acid in patients with BASD. METHODS: In this phase 3, open-label, single-arm, nonrandomized, noncomparative study conducted over 18 years, patients were administered cholic acid orally 10 to 15 mg/kg/day...
June 21, 2017: Journal of Pediatric Gastroenterology and Nutrition
https://www.readbyqxmd.com/read/28628545/salbutamol-therapy-for-food-impaction-in-eosinophilic-oesophagitis
#5
Jorge Amil Dias, Sofia Fernandes, Susana Corujeira, Eunice Trindade, Marta Tavares, Simon Murch
No abstract text is available yet for this article.
June 16, 2017: Journal of Pediatric Gastroenterology and Nutrition
https://www.readbyqxmd.com/read/28614114/primary-intestinal-lymphangiectasia-as-a-first-manifestation-of-tuberous-sclerosis-complex
#6
Natalie Boon Lin Tan, Simon Tamblyn, Rupert Hinds
No abstract text is available yet for this article.
June 13, 2017: Journal of Pediatric Gastroenterology and Nutrition
https://www.readbyqxmd.com/read/28614113/role-of-octreotide-in-pediatric-gastrointestinal-bleeding-secondary-to-angiodysplasia-in-children-with-right-heart-failure
#7
Kanika Puri, Robert Caldwell, Jean P Molleston
OBJECTIVES: Angiodysplasia is a relatively uncommon cause of GI bleeding in children and may be seen in right heart failure. Octreotide has been used successfully in adult patients with gastrointestinal bleeding due to angiodysplasias. METHODS: We describe two patients who had congenital heart disease with right heart failure and gastrointestinal bleeding from angiodysplasia. RESULTS: Angiodysplasia lesions were documented on traditional endoscopy and capsule endoscopy...
June 13, 2017: Journal of Pediatric Gastroenterology and Nutrition
https://www.readbyqxmd.com/read/28604517/espghan-guidelines-for-the-evaluation-and-treatment-of-gastrointestinal-and-nutritional-complications-in-children-with-neurological-impairment
#8
Claudio Romano, Myriam van Wynckel, Jessie Hulst, Ilse Broekaert, Jiri Bronsky, Luigi Dall'Oglio, Nataša Fidler Mis, Iva Hojsak, Rok Orel, Alexandra Papadopoulou, Michela Schaeppi, Nikhil Thapar, Michael Wilschanski, Peter Sullivan, Frédéric Gottrand
OBJECTIVES: Feeding difficulties are frequent in children with neurological impairments and can be associated with undernutrition, growth failure, micronutrients deficiencies, osteopenia and nutritional comorbidites. Gastrointestinal problems including gastroesophageal reflux disease, constipation and dysphagia are also very frequent in this population and impact quality of life and nutritional status. There is currently a lack of a systematic approach to the care of these patients. With this report, ESPGHAN aims to develop uniform guidelines for the management of the gastroenterological and nutritional problems in neurologically impaired chidren...
June 9, 2017: Journal of Pediatric Gastroenterology and Nutrition
https://www.readbyqxmd.com/read/28604516/mineral-intake-and-status-of-cow-s-milk-allergic-infants-consuming-an-amino-acid-based-formula
#9
B M Harvey, S R B M Eussen, Lucien F Harthoorn, A W Burks
Data on the mineral status of infants with cow's milk allergy (CMA) consuming an amino acid-based formula (AAF) have not been published. The present study aims to assess mineral status of term infants aged 0-8 months diagnosed with CMA receiving an AAF for 16 weeks. Serum concentrations of calcium, phosphorus, chloride, sodium, potassium, magnesium and ferritin were determined in 82 subjects at baseline and in 66 subjects after 16 weeks on AAF using standard methods and evaluated against age-specific reference ranges...
June 9, 2017: Journal of Pediatric Gastroenterology and Nutrition
https://www.readbyqxmd.com/read/28604515/novel-pressure-impedance-parameters-for-evaluating-esophageal-function-in-pediatric-achalasia
#10
Maartje M J Singendonk, Taher I Omari, Nathalie Rommel, Michiel P van Wijk, Marc A Benninga, Rachel Rosen, Samuel Nurko
OBJECTIVE: In achalasia, absent peristalsis and reduced esophagogastric junction (EGJ) relaxation and compliance underlie dysphagia symptoms. Novel high-resolution impedance manometry (HRIM) variables, i.e. bolus presence time (BPT) and trans-EGJ-bolus flow time (BFT) have been developed to estimate the duration of EGJ opening and trans-EGJ bolus flow. The aim of this study was to evaluate esophageal motor function and bolus flow in children diagnosed with achalasia using these variables...
June 9, 2017: Journal of Pediatric Gastroenterology and Nutrition
https://www.readbyqxmd.com/read/28604514/early-antibiotic-exposure-in-low-resource-settings-is-associated-with-increased-weight-in-the-first-two-years-of-life
#11
Elizabeth T Rogawski, James A Platts-Mills, Jessica C Seidman, Sushil John, Mustafa Mahfuz, Manjeswori Ulak, Sanjaya Shrestha, Sajid Bashir Soofi, Pablo Penataro Yori, Estomih Mduma, Erling Svensen, Tahmeed Ahmed, Aldo A M Lima, Zulfiqar Bhutta, Margaret Kosek, Dennis Lang, Michael Gottlieb, Anita Zaidi, Gagandeep Kang, Pascal Bessong, Eric R Houpt, Richard L Guerrant
OBJECTIVES: The potential growth-promoting effects of antibiotics are not well understood among undernourished children in environments with high pathogen exposure. We aimed to assess whether early antibiotic exposure duration and class were associated with growth to two years of age across 8 low-resource sites in the MAL-ED birth cohort study. METHODS: We followed 1,954 children twice per week from birth to two years to record maternally-reported antibiotic exposures and measure anthropometry monthly...
June 9, 2017: Journal of Pediatric Gastroenterology and Nutrition
https://www.readbyqxmd.com/read/28604513/severe-sarcopenia-and-increased-fat-stores-in-pediatric-patients-with-liver-kidney-or-intestine-failure
#12
Richard S Mangus, Weston J Bush, Chandrashekhar A Kubal, Christina Miller
OBJECTIVES: Malnutrition and wasting predict clinical outcomes in children with severe chronic illness. Objectively calculated malnutrition in children with end-stage organ failure has not been well studied. This analysis compares children with kidney, liver or intestine failure to healthy controls to quantitate the disparity in muscle and fat stores. METHODS: Children younger than age 19 with end stage liver, kidney or intestine failure and with pre-transplant computed tomography (CT) imaging were selected from the transplant database...
June 9, 2017: Journal of Pediatric Gastroenterology and Nutrition
https://www.readbyqxmd.com/read/28604512/changes-in-hepcidin-and-hemoglobin-after-anti-tnf-alpha-therapy-in-children-and-adolescents-with-crohn-s-disease
#13
Meredith A Atkinson, Mary B Leonard, Rita Herskovitz, Robert N Baldassano, Michelle R Denburg
BACKGROUND: Anemia is the most common systemic complication of inflammatory bowel disease, is more common in affected children than adults, and is mediated in large part by chronic inflammation. Inflammation increases levels of the iron-regulatory protein hepcidin, which have been elevated in adults with Crohn's disease. METHODS: We measured serum hepcidin-25 and hemoglobin (Hgb) in 40 children and adolescents with Crohn's disease at baseline and 10 weeks after initiation of anti-TNF-α therapy...
June 9, 2017: Journal of Pediatric Gastroenterology and Nutrition
https://www.readbyqxmd.com/read/28604511/incidence-and-risk-factors-for-perianal-disease-in-pediatric-crohn-s-disease-patients-followed-in-cedata-gpge-registry
#14
Annecarin Brückner, Katharina J Werkstetter, Jan de Laffolie, Claudia Wendt, Christine Prell, Tanja Weidenhausen, Klaus P Zimmer, Sibylle Koletzko
BACKGROUND AND AIMS: Perianal disease (PD) with fistula and/or abscess formation is a severe complication in Crohn's disease (CD). We examined prevalence, incidence and risk factors for PD development in a pediatric CD cohort. METHODS: CD patients from the prospective, multi-center registry for inflammatory bowel disease from Germany and Austria (CEDATA-GPGE) were included if diagnosed ≤18 years of age, registered within three months after diagnosis, and having at least two follow-up visits within the first year of registration...
June 9, 2017: Journal of Pediatric Gastroenterology and Nutrition
https://www.readbyqxmd.com/read/28604510/safety-and-efficacy-of-the-push-endoscopic-technique-in-the-management-of-esophageal-food-bolus-impactions-in-children
#15
Jamal Kriem, Riad Rahhal
OBJECTIVES: Adult-based guidelines support the use of the pull (extraction) endoscopic technique in managing esophageal food bolus impactions (FBIs) but allow the consideration of the push (advancement) technique with caution based on available published literature. The North American Society of Pediatric Gastroenterology, Hepatology and Nutrition guidelines mention the use of gentle endoscopic pushing for disimpaction but elaborate that this technique has not been studied in children...
June 9, 2017: Journal of Pediatric Gastroenterology and Nutrition
https://www.readbyqxmd.com/read/28604509/granulocyte-and-monocyte-apheresis-for-induction-of-remission-in-children-with-new-onset-inflammatory-bowel-colitis
#16
Helena Rolandsdotter, Michael Eberhardson, Ulrika L Fagerberg, Yigael Finkel
OBJECTIVE: To study the effect of granulocyte and monocyte apheresis (GMA) with mesalazine for induction of remission in pediatric patients with newly onset chronic inflammatory bowel disease (IBD) colitis. METHODS: Thirteen pediatric patients with newly onset extensive IBD colitis were investigated per the ECCO/ESPGHAN IBD protocol. Of these 13, 12 received ten treatments with Adacolumn (ADA) during a median of 6.25 weeks in combination with low-to-moderate doses of mesalazine, which was continued after apheresis...
June 9, 2017: Journal of Pediatric Gastroenterology and Nutrition
https://www.readbyqxmd.com/read/28582312/development-of-nerve-fibre-diameter-in-young-infants-with-hirschsprung-disease
#17
Maarten Janssen Lok, Roxana Rassouli-Kirchmeier, Nils Köster, Benno Kusters, Ivo de Blaauw
OBJECTIVES: Finding thickened nerve fibres is one of the key elements in the diagnosis of Hirschsprung Disease (HD); however, its value at different ages remains uncertain. Nerve fibre diameters <40 μm can be observed in infants younger than 8 weeks, despite the presence of HD. The aim of this study was to identify a change in maximum nerve fibre diameter in HD patients, measured before and after 8 weeks of age. METHODS: Nerve fibre diameter was retrospectively evaluated in tissue of 20 infants treated for definite HD...
June 2, 2017: Journal of Pediatric Gastroenterology and Nutrition
https://www.readbyqxmd.com/read/28574971/per-oral-endoscopic-myotomy-in-children-first-experience-with-a-new-triangular-knife
#18
Zaheer Nabi, Mohan Ramchandani, Radhika Chavan, Manu Tandan, Rakesh Kalapala, Santosh Darisetty, D Nageshwar Reddy
OBJECTIVES: Per-oral endoscopic myotomy (POEM) is a novel treatment modality for achalasia cardia (AC). The procedure is technically challenging and time consuming. Recently, a new triangle knife (TTJ) has been introduced which is equipped with water jet facility. In this study, we analysed the feasibility, safety and efficacy of POEM in children with new triangle tip knife. METHODS: We retrospectively evaluated the data of children (≤18 years) who underwent POEM using TTJ knife at our institution...
June 2, 2017: Journal of Pediatric Gastroenterology and Nutrition
https://www.readbyqxmd.com/read/28574970/probiotics-for-the-prevention-of-nosocomial-diarrhea-in-children
#19
Iva Hojsak, Hania Szajewska, Roberto Berni Canani, Alfredo Guarino, Flavia Indrio, Sanja Kolacek, Rok Orel, Raanan Shamir, Yvan Vandenplas, Johannes B van Goudoever, Zvi Weizman
This document provides recommendations developed by the ESPGHAN Working Group (WG) on Probiotics and Prebiotics on the role of probiotics in the prevention of nosocomial diarrhea in children based on a systematic review of previously completed systematic reviews and of subsequently published randomized controlled trials (RCTs). The quality of evidence was assessed using the Grading of Recommendations Assessment, Development and Evaluation (GRADE) guidelines. Recommendations were given only if at least 2 RCTs examined the same probiotic strain...
June 2, 2017: Journal of Pediatric Gastroenterology and Nutrition
https://www.readbyqxmd.com/read/28574969/daily-experiences-and-challenges-among-children-and-adolescents-with-celiac-disease-focus-group-results
#20
Sonya Meyer, Sara Rosenblum
OBJECTIVES: Maintaining a restrictive gluten-free diet is the only treatment for celiac disease (CD). Adherence among children and adolescents presents unique challenges and is often inadequate. The International Classification of Functioning, Disability and Health: Children and Youth version (ICF-CY) model encompasses all aspects of human health and daily function while dealing with a disease and interacting with the environment. The purpose was to explore everyday life experiences and challenges as perceived by children and adolescents with CD and their parents in light of the ICF-CY concepts to identify the most crucial components in management challenges...
June 2, 2017: Journal of Pediatric Gastroenterology and Nutrition
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