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Journal of Pediatric Gastroenterology and Nutrition

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https://www.readbyqxmd.com/read/30028829/is-the-who-creating-unnecessary-confusion-over-breast-milk-substitutes
#1
Stewart Forsyth
A recent statement by WHO that "breast milk substitutes should be understood to include any milks …that are specifically marketed for feeding infants and young children up to the age of 3 years" differs significantly from the definition in the International Code which states "a breast milk substitute is any food being marketed or otherwise presented as a partial or total replacement for breast milk, whether or not suitable for that purpose." The new interpretation, which lacks consultation and endorsement, is also ambiguous, with the boundaries between breast milk substitutes and complementary foods being blurred during the first 3 years of life...
July 19, 2018: Journal of Pediatric Gastroenterology and Nutrition
https://www.readbyqxmd.com/read/30028828/growth-body-composition-and-micronutrient-abnormalities-during-and-after-weaning-off-home-parenteral-nutrition
#2
Esther Neelis, Joanne Olieman, Dimitris Rizopoulos, René Wijnen, Edmond Rings, Barbara de Koning, Jessie Hulst
OBJECTIVES: To assess growth, body composition and micronutrient abnormalities in children with intestinal failure (IF) over time, both during and after weaning off parenteral nutrition (PN). METHODS: Retrospective study in children on home PN between 2001 and 2015. Weight-for-age (WFA) and height-for-age (HFA) SD scores (SDS) were calculated, as well as fat mass (FM) and fat free mass (FFM) SDS obtained by DEXA. The course of growth parameters and body composition was analyzed with linear mixed models...
July 19, 2018: Journal of Pediatric Gastroenterology and Nutrition
https://www.readbyqxmd.com/read/30028827/liver-biopsy-can-be-safely-performed-in-pediatric-acute-liver-failure-to-aid-in-diagnosis-and-management
#3
Catherine A Chapin, Saeed Mohammad, Lee M Bass, Sarah A Taylor, Susan Kelly, Estella M Alonso
OBJECTIVES: Liver biopsy can be a valuable tool to help determine the etiology of pediatric acute liver failure (PALF), but is often not performed due to safety concerns. The primary aim was to describe the incidence of major complications after liver biopsy performed in the setting of PALF. METHODS: Medical records from 2006-2016 were reviewed. Patients age 0-17 years, who met criteria for PALF, and had a liver biopsy performed while their international normalized ratio (INR) was ≥1...
July 19, 2018: Journal of Pediatric Gastroenterology and Nutrition
https://www.readbyqxmd.com/read/30024862/preparation-of-powdered-infant-formula-could-product-s-safety-be-improved
#4
Marina-Nadia Losio, Enrico Pavoni, Guido Finazzi, Carlo Agostoni, Paolo Daminelli, Elena Dalzini, Giorgio Varisco, Stefano Cinotti
The recent outbreak of Salmonella Agona linked to the consumption of infant formula (powdered formula) has rekindled the attention about the correct procedures for preparation and use of these products. International guidelines have already been published so far, particularly in association with Cronobacter sakazakii in early 2000's. FAO/WHO suggested to reconstitute formula with water at no less than 70°C. We therefore contaminated powdered formula with low levels of Salmonella spp. and C. sakazakii to evaluate the pathogens inactivation during the formula preparation using water at 70°C...
July 18, 2018: Journal of Pediatric Gastroenterology and Nutrition
https://www.readbyqxmd.com/read/29985879/response-to-letter-to-the-editor
#5
Jonathan E Markowitz
No abstract text is available yet for this article.
July 6, 2018: Journal of Pediatric Gastroenterology and Nutrition
https://www.readbyqxmd.com/read/29985878/efficacy-of-reslizumab-for-eosinophilic-esophagitis
#6
George J Fuchs
No abstract text is available yet for this article.
July 6, 2018: Journal of Pediatric Gastroenterology and Nutrition
https://www.readbyqxmd.com/read/29985877/switching-from-originator-to-biosimilar-infliximab-in-paediatric-inflammatory-bowel-disease-is-feasible-and-uneventful
#7
Lisa Gervais, Luke L McLean, Michelle L Wilson, Carol Cameron, Lee Curtis, Vikki Garrick, Kat Armstrong, Rachel Tayler, Paul Henderson, Richard Hansen, Iain Chalmers, David C Wilson, Richard K Russell
The safety, clinical efficacy and cost-effectiveness of biosimilar infliximab in adult inflammatory bowel disease (IBD) have now been extensively shown. Limited data has been collected in the paediatric setting. We report nationwide, prospective, clinical safety and effectiveness data for patients from all three Scottish paediatric IBD (PIBD) networks switching from originator to biosimilar infliximab.Prospective clinical data was collected for 33 patients. Information was collected from electronic patient records, laboratory reports and patient case notes...
July 6, 2018: Journal of Pediatric Gastroenterology and Nutrition
https://www.readbyqxmd.com/read/29985876/a-rare-case-of-a-2-year-old-boy-with-alagille-syndrome-type-3-hereditary-hemochromatosis-with-tfr2-mutation
#8
Ammar A Khayat, Mariko Suchi, Bernadette Vitola
No abstract text is available yet for this article.
July 6, 2018: Journal of Pediatric Gastroenterology and Nutrition
https://www.readbyqxmd.com/read/29985875/genetic-diversity-of-norovirus-infections-co-infections-and-undernutrition-in-children-from-brazilian-semiarid-region
#9
Rafhaella D G Gondim, Rafaela C Pankov, Mara M G Prata, Pedro H Q S Medeiros, Herlice N Veras, Ana K S Santos, Lyvia M C Magalhães, Alexandre Havt, Tulio M Fumian, Marize P Miagostovich, José P G Leite, Aldo A M Lima
BACKGROUND: Norovirus (NoV) infections are known to have high morbidity and mortality rates and are a major health problem globally. However, the impact of NoV on child development is poorly understood. OBJECTIVE: We evaluated the distribution of NoV genotypes in children from a low-income Brazilian semiarid region, in relation with their clinical symptoms, nutritional status, and co-pathogens. METHODS: The test population included children aged 2-36 months from six cities of the Brazilian semiarid region...
July 6, 2018: Journal of Pediatric Gastroenterology and Nutrition
https://www.readbyqxmd.com/read/29985874/erythromycin-and-reflux-events-in-premature-neonates-a-randomized-clinical-trial
#10
Cortney R Ballengee, Faranek Davalian, Mark R Conaway, Cary G Sauer, David A Kaufman
OBJECTIVE: Gastroesophageal reflux disease (GERD) in premature neonates may manifest as apnea, bradycardia, growth failure, aspiration or feeding intolerance. Erythromycin ethylsuccinate (EES), is often used as a pro-kinetic in the management of GERD, despite lack of evidence or safety from randomized controlled trials. We sought to study the efficacy of enteral EES at a dose of 50 mg/kg/day in decreasing the frequency of GER events as determined by pH-multichannel intraluminal impedance (pH-MII) monitoring...
July 6, 2018: Journal of Pediatric Gastroenterology and Nutrition
https://www.readbyqxmd.com/read/29985873/piecemeal-deglutition-and-the-implications-for-pressure-impedance-dysphagia-assessment-in-pediatrics
#11
Lara Ferris, Sebastian King, Lisa McCall, Nathalie Rommel, Ingrid Scholten, Warwick Teague, Sebastian Doeltgen, Taher Omari
OBJECTIVES: High resolution impedance manometry (HRIM) enables biomechanical swallow assessment. Piecemeal deglutition (PD) defines swallowing of a single bolus in two or more portions. We investigated PD sequences on HRIM recordings to ascertain appropriate swallow selection for analysis and to determine the impact of PD on swallow function measures. METHODS: Pharyngo-esophageal motility and bolus flow were assessed in 27 children (19 M, mean age 15 months) with repaired esophageal atresia and trachea-esophageal fistula, but who were asymptomatic of oropharyngeal dysphagia...
July 6, 2018: Journal of Pediatric Gastroenterology and Nutrition
https://www.readbyqxmd.com/read/29985872/newborn-exposure-to-polycyclic-aromatic-hydrocarbons-through-parenteral-nutrition
#12
Denise Bohrer, Marcia M Barichello, Carine Viana, Paulo C Nascimento, Leandro M Carvalho
BACKGROUND: Parenteral nutrition (PN) administered to newborns (NB) may be contaminated with polycyclic aromatic hydrocarbons (PAHs) and may therefore increase the contact with these toxicants in very early life stages. OBJECTIVES: To determine to what extent, if any, commercial products for parenteral nutrition are contaminated with PAHs. To determine whether these contaminants, when present in the bag content, are delivered to NB and whether 1-hydroxypyrene (1-HP), the pyrene metabolite, can be detected in the urine of exposed NB...
July 6, 2018: Journal of Pediatric Gastroenterology and Nutrition
https://www.readbyqxmd.com/read/29958254/indications-for-helicobacter-pylori-eradication-do-we-need-to-consider-to-screen-and-treat-asymptomatic-children
#13
Yalda Lucero, Sergio George, Miguel O'Ryan
No abstract text is available yet for this article.
June 28, 2018: Journal of Pediatric Gastroenterology and Nutrition
https://www.readbyqxmd.com/read/29958253/a-diagnostic-algorithm-for-cholesteryl-ester-storage-disease-clinical-presentation-in-19-polish-patients
#14
Patryk Lipiński, Agnieszka Ługowska, Ekaterina Y Zakharova, Piotr Socha, Anna Tylki-Szymańska
INTRODUCTION: Lysosomal acid lipase deficiency (LAL-D) is a rare autosomal recessive lysosomal lipid storage disorder that results in an early-onset, severe and lethal phenotype, known as Wolman disease, or a late-onset, attenuated phenotype, cholesteryl ester storage disease (CESD).The aim of our study was to describe the clinical presentation of CESD, focusing on the first noted abnormalities in patients. A diagnostic algorithm of CESD was also proposed. METHODS AND RESULTS: This is an observational, one-centre study of 19 Polish patients with late-onset LAL-D...
June 28, 2018: Journal of Pediatric Gastroenterology and Nutrition
https://www.readbyqxmd.com/read/29952830/variceal-bleeding-and-morbidity-considerations-for-primary-prophylaxis
#15
Lee M Bass
No abstract text is available yet for this article.
June 26, 2018: Journal of Pediatric Gastroenterology and Nutrition
https://www.readbyqxmd.com/read/29952829/polyethylene-glycol-maintenance-treatment-for-childhood-functional-constipation-a-randomized-placebo-controlled-trial
#16
Line Modin, Anne Mette Walsted, Kasper Dalby, Marianne Skytte Jakobsen
OBJECTIVE: To investigate the long-term efficacy of polyethylene glycol (PEG) during maintenance treatment of childhood functional constipation (FC) in a randomized, double-blinded, placebo-controlled trial. METHODS: Children (2-16y) with FC according to the Rome III criteria were randomly assigned to maintenance treatment with PEG or placebo for 24 wk. Children reporting treatment failure before 24 wk were switched to conventional treatment. Primary outcome was successful treatment, defined as absence of any Rome III criteria with or without use of medication after 24 wk...
June 26, 2018: Journal of Pediatric Gastroenterology and Nutrition
https://www.readbyqxmd.com/read/29952828/dehydrated-hereditary-stomatocytosis-presenting-as-severe-perinatal-ascites-and-cholestasis
#17
Jennifer Halma, Joshua Petrikin, James F Daniel, Ryan T Fischer
No abstract text is available yet for this article.
June 26, 2018: Journal of Pediatric Gastroenterology and Nutrition
https://www.readbyqxmd.com/read/29952827/physical-activity-and-skipping-breakfast-have-independent-effects-on-body-fatness-among-adolescents
#18
Suziane Ungari Cayres, Jacqueline Bexiga Urban, Rômulo Araújo Fernandes
OBJECTIVE: We analyzed the longitudinal relationship between breakfast intake and adiposity among adolescents, and the possible mediation role of physical activity on this phenomenon. METHODS: We conducted the longitudinal study composed of 86 adolescents (11 to 14 years-old), absence of any known chronic diseases and no regular medicine use that returned the formal consent and assent both signed. Breakfast intake was reported through face-to-face interviews. Adiposity was assessed using a densitometry scanner...
June 26, 2018: Journal of Pediatric Gastroenterology and Nutrition
https://www.readbyqxmd.com/read/29927866/anorectal-manometry-for-the-diagnosis-of-hirschsprung-disease-new-heights-for-the-balloon-or-just-hot-air
#19
Nikhil Thapar, Osvaldo Borrelli
No abstract text is available yet for this article.
June 20, 2018: Journal of Pediatric Gastroenterology and Nutrition
https://www.readbyqxmd.com/read/29927865/infant-feeding-practices-and-the-effect-in-reducing-functional-constipation-six-years-later-a-randomised-field-trial
#20
Caroline Nicola Sangalli, Paula Dos Santos Leffa, Mauro Batista de Morais, Márcia Regina Vitolo
OBJECTIVE: To assess the impact of health worker training on infant feeding practices on the prevalence of functional constipation among children at six years of age. METHODS: Cluster randomised field trial conducted in Porto Alegre, Brazil. Health centers were randomly allocated into intervention (n = 9) or control (n = 11) groups. In intervention sites, health workers joined training sessions on the "Ten Steps for Healthy Feeding for Children from Birth to Two Years of age"...
June 20, 2018: Journal of Pediatric Gastroenterology and Nutrition
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