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Journal of Pediatrics

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https://www.readbyqxmd.com/read/28942898/the-need-for-pediatric-drug-development
#1
Robert M Ward, Daniel K Benjamin, Jonathan M Davis, Richard L Gorman, Ralph Kauffman, Gregory L Kearns, Mary Dianne Murphy, Catherine M T Sherwin
No abstract text is available yet for this article.
September 21, 2017: Journal of Pediatrics
https://www.readbyqxmd.com/read/28942897/can-we-cure-bronchopulmonary-dysplasia
#2
Bernard Thébaud, Stella Kourembanas
No abstract text is available yet for this article.
September 21, 2017: Journal of Pediatrics
https://www.readbyqxmd.com/read/28918883/pseudoparalysis-of-parrot-a-diagnostic-aid-in-congenital-syphilis
#3
Annelyse Araújo Pereira, Sandra Márcia Castro, Ranielly Ribeiro Venturini, Fernanda Oliveira César, Patricia Marques Fortes, Paulo Sucasas Costa
No abstract text is available yet for this article.
September 14, 2017: Journal of Pediatrics
https://www.readbyqxmd.com/read/28918882/genome-wide-associations-related-to-hepatic-histology-in-nonalcoholic-fatty-liver-disease-in-hispanic-boys
#4
Julia Wattacheril, Joel E Lavine, Naga P Chalasani, Xiuqing Guo, Soonil Kwon, Jeffrey Schwimmer, Jean P Molleston, Rohit Loomba, Elizabeth M Brunt, Yii-Der Ida Chen, Mark O Goodarzi, Kent D Taylor, Katherine P Yates, James Tonascia, Jerome I Rotter
OBJECTIVE: To identify genetic loci associated with features of histologic severity of nonalcoholic fatty liver disease in a cohort of Hispanic boys. STUDY DESIGN: There were 234 eligible Hispanic boys age 2-17 years with clinical, laboratory, and histologic data enrolled in the Nonalcoholic Steatohepatitis Clinical Research Network included in the analysis of 624 297 single nucleotide polymorphisms (SNPs). After the elimination of 4 outliers and 22 boys with cryptic relatedness, association analyses were performed on 208 DNA samples with corresponding liver histology...
September 14, 2017: Journal of Pediatrics
https://www.readbyqxmd.com/read/28918881/clinical-detection-of-hemodynamically-significant-isolated-secundum-atrial-septal-defect
#5
Robert L Geggel
The diagnosis of secundum atrial septal defect often is delayed. For 310 patients with hemodynamically significant secundum atrial septal defect undergoing closure over a 5-year period at a single medical center, this study reviews the symptoms prompting referral, limitations of physical examination and electrocardiography, and basis for initially missing the diagnosis.
September 14, 2017: Journal of Pediatrics
https://www.readbyqxmd.com/read/28918880/iliac-subperiosteal-hematoma-with-ossification-in-a-15-year-old-boy
#6
Sun Hwa Lee, Seong Jong Yun
No abstract text is available yet for this article.
September 14, 2017: Journal of Pediatrics
https://www.readbyqxmd.com/read/28917956/bowel-dilation-diagnosed-prenatally
#7
Taieb Chouikh, Nicolas Mottet, Marion Lenoir, Yann Chaussy
No abstract text is available yet for this article.
September 13, 2017: Journal of Pediatrics
https://www.readbyqxmd.com/read/28917955/lidocaine-gel-for-urethral-catheterization-in-children-a-meta-analysis
#8
Michael E Chua, Paul Nimrod B Firaza, Jessica M Ming, Jan Michael A Silangcruz, Luis H Braga, Armando J Lorenzo
OBJECTIVE: To compare the efficacy and safety of lidocaine gel vs nonanesthetic gel (NAG) in reducing transurethral bladder catheterization (TUBC) procedural pain in children. STUDY DESIGN: A systematic literature search was done using electronic medical databases and trial registries up to September 2016 with no language restrictions. Randomized controlled trials (RCTs) that assessed the efficacy and safety of lidocaine gel vs NAG in reducing TUBC-associated pain in children were screened, identified, and appraised...
September 13, 2017: Journal of Pediatrics
https://www.readbyqxmd.com/read/28917954/-striatal-toe-sign-false-positive-extensor-plantar-response-in-dystonia
#9
Debabrata Ghosh
No abstract text is available yet for this article.
September 13, 2017: Journal of Pediatrics
https://www.readbyqxmd.com/read/28912052/assessing-children-s-report-of-stool-consistency-agreement-between-the-pediatric-rome-iii-questionnaire-and-the-bristol-stool-scale
#10
Mana H Vriesman, Carlos A Velasco-Benitez, Carmen R Ramirez, Marc A Benninga, Carlo Di Lorenzo, Miguel Saps
OBJECTIVES: To assess the agreement between the Questionnaire on Pediatric Gastrointestinal Symptoms-Rome III (QPGS-RIII) and the Bristol Stool Scale (BSS) in evaluating stool consistency and the diagnosis of functional constipation in children. STUDY DESIGN: Children aged 8-18 years were asked to describe their stool consistency in the previous month according to the QPGS-RIII and the BSS. Stool consistency according to both instruments was categorized into 3 categories: "hard," "normal," and "liquid...
September 11, 2017: Journal of Pediatrics
https://www.readbyqxmd.com/read/28912051/the-relationship-between-coronary-artery-disease-risk-factors-and-carotid-intima-media-thickness-in-children
#11
Dan White, Rebecca Place, Timothy Michael, Eric Hoffman, Paul M Gordon, Paul Visich
OBJECTIVE: To determine the number of coronary artery disease risk factors and the individual coronary artery disease risk factors that have a negative influence on carotid intima-media thickness in children. STUDY DESIGN: One hundred and nineteen children (mean age 10.51 ± 0.52 years; 51% female) participated. Each subject was assessed for carotid intima-media thickness, total cholesterol, high-density lipoprotein cholesterol (HDL-C), glucose, body mass index (BMI), and resting blood pressure...
September 11, 2017: Journal of Pediatrics
https://www.readbyqxmd.com/read/28912050/pancreatic-enzyme-replacement-therapy-in-children-with-severe-acute-malnutrition-a-randomized-controlled-trial
#12
Rosalie H Bartels, Céline Bourdon, Isabel Potani, Brian Mhango, Deborah A van den Brink, John S Mponda, Anneke C Muller Kobold, Robert H Bandsma, Michael Boele van Hensbroek, Wieger P Voskuijl
OBJECTIVE: To assess the benefits of pancreatic enzyme replacement therapy (PERT) in children with complicated severe acute malnutrition. STUDY DESIGN: We conducted a randomized, controlled trial in 90 children aged 6-60 months with complicated severe acute malnutrition at the Queen Elizabeth Central Hospital in Malawi. All children received standard care; the intervention group also received PERT for 28 days. RESULTS: Children treated with PERT for 28 days did not gain more weight than controls (13...
September 11, 2017: Journal of Pediatrics
https://www.readbyqxmd.com/read/28893384/influence-of-socioeconomic-context-on-the-rehospitalization-rates-of-infants-born-preterm
#13
Olivia Laugier, Patricia Garcia, Mohamed Boucékine, Alexandre Daguzan, Sophie Tardieu, Roland Sambuc, Farid Boubred
OBJECTIVE: To investigate the impact of social inequalities on the risk of rehospitalization in the first year after discharge from the neonatal unit in a population of preterm-born children. STUDY DESIGN: Preterm infants were included if they were born between 2006 and 2013 at ≤32 + 6 weeks of gestation and who received follow-up in a French regional medical network with a high level of healthcare. Socioeconomic context was estimated using a neighborhood-based socioeconomic deprivation index...
September 8, 2017: Journal of Pediatrics
https://www.readbyqxmd.com/read/28890205/shivering-in-febrile-children-frequency-and-usefulness-in-predicting-serious-bacterial-infections-a-prospective-case-control-study
#14
Yair Erell, Ilan Youngster, Ibrahim Abu-Kishk, Eran Kozer
A prospective case-control study was conducted in a pediatric emergency department to describe the proportion of febrile children experiencing shivering and its clinical significance. Shivering was reported in 186 of 645 febrile children (28.8%). The rate of serious bacterial infection was similar in 86 children with shivering and 86 matched controls.
September 7, 2017: Journal of Pediatrics
https://www.readbyqxmd.com/read/28890204/early-caffeine-prophylaxis-and-risk-of-failure-of-initial-continuous-positive-airway-pressure-in-very-low-birth-weight-infants
#15
Ravi M Patel, Kanecia Zimmerman, David P Carlton, Reese Clark, Daniel K Benjamin, P Brian Smith
OBJECTIVE: To test the hypothesis that early caffeine treatment on the day of birth, compared with later treatment in very low birth weight (VLBW, <1500 g) infants receiving continuous positive airway pressure (CPAP) therapy, is associated with a decreased risk of CPAP failure in the first week of life. STUDY DESIGN: Multicenter, observational cohort study in 366 US neonatal intensive care units. We evaluated inborn, VLBW infants discharged from 2000 to 2014, who received only CPAP therapy without surfactant treatment on day of life (DOL) 0, had a 5-minute Apgar ≥3, and received caffeine in first week of life...
September 7, 2017: Journal of Pediatrics
https://www.readbyqxmd.com/read/28888565/the-use-of-echocardiography-for-pediatric-patients-presenting-with-syncope
#16
Jonathan H Pelletier, Sarah Blanchard, Reid C Chamberlain, Christoph P Hornik, Michael J Campbell, Kevin D Hill
OBJECTIVES: To assess the frequency, yield, and cost of echocardiograms meeting "rarely appropriate" criteria. STUDY DESIGN: Retrospective, single-center study of pediatric patients presenting with syncope. Patients were categorized according to the appropriate use criteria and based upon location of care (emergency department only, primary care setting only, or referred to a pediatric cardiologist). Multivariable regression was used to determine factors associated with performance of a "rarely appropriate" echocardiogram...
September 6, 2017: Journal of Pediatrics
https://www.readbyqxmd.com/read/28888564/everolimus-for-the-treatment-of-tuberous-sclerosis-complex-related-cardiac-rhabdomyomas-in-pediatric-patients
#17
Nagib Dahdah
No abstract text is available yet for this article.
September 6, 2017: Journal of Pediatrics
https://www.readbyqxmd.com/read/28888563/bilirubin-uridine-diphosphate-glucuronosyltransferase-polymorphism-as-a-risk-factor-for-prolonged-hyperbilirubinemia-in-japanese-preterm-infants
#18
Takahide Yanagi, Sayuri Nakahara, Yoshihiro Maruo
OBJECTIVE: To determine whether a variant of the bilirubin uridine diphosphate-glucuronosyltransferase gene (UGT1A1*6) is a risk factor for prolonged hyperbilirubinemia in preterm infants. STUDY DESIGN: UGT1A1 genotypes in 46 Japanese preterm infants (<37 weeks of gestation) were compared with UGT1A1 genotypes in 38 control infants, using polymerase chain reaction-direct sequencing. Prolonged unconjugated hyperbilirubinemia was defined as serum total bilirubin concentration of >150 µmol/L (8...
September 6, 2017: Journal of Pediatrics
https://www.readbyqxmd.com/read/28888562/timing-and-chronicity-of-maternal-depression-symptoms-and-children-s-verbal-abilities
#19
Marilyn N Ahun, Marie-Claude Geoffroy, Catherine M Herba, Mara Brendgen, Jean R Séguin, Anne-Laure Sutter-Dallay, Michel Boivin, Richard E Tremblay, Sylvana M Côté
OBJECTIVE: To test the associations between the timing and chronicity of maternal depression symptoms (MDS) and children's long-term verbal abilities. STUDY DESIGN: Participants were 1073 mother-child pairs from a population-based birth cohort in Canada. MDS were assessed at ages 5 months, 1.5, 3.5, and 5 years using the Center for Epidemiologic Studies Depression Scale. Verbal abilities were measured at 5, 6, and 10 years using the Peabody Picture Vocabulary Test-Revised (PPVT-R)...
September 6, 2017: Journal of Pediatrics
https://www.readbyqxmd.com/read/28888561/delayed-presentation-and-prolonged-survival-of-a-child-with-surfactant-protein-b-deficiency
#20
Juan A López-Andreu, Antonio D Hidalgo-Santos, Miguel A Fuentes-Castelló, Nuria Mancheño-Franch, Juan A Cerón-Pérez, Maria J Esteban-Ricós, Laia Pedrola-Vidal, Lawrence M Nogee
Surfactant protein B encoding gene mutations have been related to early onset fatal respiratory distress in full-term neonates. We report a school-aged male child homozygous for a surfactant protein B encoding gene missense mutation who presented after the neonatal period. His respiratory insufficiency responded to high dose intravenous methylprednisolone and hydroxychloroquine.
September 6, 2017: Journal of Pediatrics
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