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Journal of Pediatrics

Ania M Jastreboff, Tara M Chaplin, Sheridan Finnie, Mary Savoye, Matthew Stults-Kolehmainen, Wendy K Silverman, Rajita Sinha
OBJECTIVE: To assess the feasibility of engaging stressed, low-income parents with obesity in a novel mindfulness-based parent stress intervention aimed at decreasing the risk of early childhood obesity. STUDY DESIGN: An 8-week mindfulness-based parent stress group intervention (parenting mindfully for health) plus nutrition and physical activity counseling (PMH+N) was developed for parents with obesity aimed at preventing obesity in their at-risk 2- to 5-year-old children...
September 18, 2018: Journal of Pediatrics
Savithri Nageswaran, Shannon L Golden, W Adam Gower, Nancy M P King
OBJECTIVE: To describe the perceptions of caregivers of children with medical complexity (CMC) about their decision to pursue tracheostomy for their children, in particular the satisfaction with their decision. STUDY DESIGN: In this qualitative study conducted in western North Carolina between 2013 and 2014, we interviewed 56 caregivers of 41 CMC who had received tracheostomies in the past 5 years. Three of the CMC were deceased at the time of the interview; 8 were decannulated...
September 17, 2018: Journal of Pediatrics
Nicole Fortier O'Brien, Tshimanga Mutatshi Taty, Melissa Moore-Clingenpeel, Joseph Bodi Mabiala, Jean Mbaka Pongo, Davin Ambitapio Musungufu, Mananu Uchama, Marcel Yotebieng
OBJECTIVE: To evaluate neurovascular changes in pediatric patients with cerebral malaria. STUDY DESIGN: African children with cerebral malaria were enrolled and underwent daily transcranial Doppler ultrasound (TCD) examinations through hospital day 8, discharge, or death. Neurologic outcomes were assessed 2 weeks after enrollment. RESULTS: In total, 160 children with cerebral malaria and 155 comparison patients were included. In patients with cerebral malaria, TCD flow changes characterized as hyperemia were seen in 42 (26%), low flow in 46 (28%), microvascular obstruction in 35 (22%), cerebral vasospasm in 21 (13%), and isolated posterior hyperemia in 7 (4%)...
September 14, 2018: Journal of Pediatrics
Kristin L Berg, Cheng-Shi Shiu, Rebecca T Feinstein, Michael E Msall, Kruti Acharya
OBJECTIVE: To explore associations between level of adverse childhood experiences (ACEs) and unmet healthcare needs among children with autism spectrum disorder (ASD) using a population-based sample. STUDY DESIGN: Cross-sectional data from the 2011-2012 National Survey of Child Health were analyzed to estimate prevalence of unmet healthcare needs among children with ASD, aged 2-17 years (ASD = 1624; estimated population = 1 174 871). Multivariate Poisson and logistic regression models were used to estimate the relationship between reported ACEs and unmet healthcare needs among children with ASD...
September 14, 2018: Journal of Pediatrics
Veeral N Tolia, Karna Murthy, Monica M Bennett, Rachel G Greenberg, Daniel K Benjamin, P Brian Smith, Reese H Clark
OBJECTIVE: To estimate the relationship of initial pharmacotherapy with methadone or morphine and length of stay (LOS) in infants with neonatal abstinence syndrome (NAS) admitted to the neonatal intensive care unit (NICU). STUDY DESIGN: From the Pediatrix Clinical Data Warehouse database, we identified all infants born at ≥36 weeks of gestation between 2011 and 2015 who were diagnosed with NAS (International Classification of Diseases, Ninth Revision code 779...
September 14, 2018: Journal of Pediatrics
Koen Zwart, Dirk-Jan Van Ginkel, Caroline C C Hulsker, Marieke J Witvliet, Maud Y A Van Herwaarden-Lindeboom
OBJECTIVES: To evaluate whether the application of mechanical bowel preparation (MBP) before colorectal surgery reduces the risk of developing infectious complications in children. STUDY DESIGN: In this systematic review and meta-analysis, PubMed, Embase, and the Cochrane Library were systematically searched to identify all articles comparing pediatric patients receiving MBP with pediatric patients not receiving MBP before colorectal surgery. Results are presented with weighted risk differences based on the number of events and sample size per study...
September 12, 2018: Journal of Pediatrics
Karna Murthy, Nicolas F M Porta, Eugenia K Pallotto, Natalie Rintoul, Sarah Keene, Louis Chicoine, Jason Gien, Beverly S Brozanski, Yvette R Johnson, Beth Haberman, Robert DiGeronimo, Isabella Zaniletti, Theresa R Grover
OBJECTIVE: To predict incident bloodstream infection and urinary tract infection (UTI) in infants with congenital diaphragmatic hernia (CDH). STUDY DESIGN: We conducted a retrospective analysis using the Children's Hospital Neonatal Database during 2010-2016. Infants with CDH admitted at 22 participating regional neonatal intensive care units were included; patients repaired or discharged to home prior to admission/referral were excluded. The primary outcome was death or the occurrence of bloodstream infection or UTI prior to discharge...
September 11, 2018: Journal of Pediatrics
Bibhuti B Das, Maryanne Chrisant, Gerald Lavandosky, Megan Zakrzewski, Robert Winchester, Immanuel Turner, Steven Bibevski, Frank Scholl
No abstract text is available yet for this article.
September 11, 2018: Journal of Pediatrics
Katelyn Gordon, Linda Dynan, Robert Siegel
OBJECTIVE: To describe school cafeteria interventions in terms of a behavioral economics scheme and to assess which system is more likely to be effective in improving food selection or consumption. STUDY DESIGN: With this systematic review, we categorize cafeteria interventions using the behavioral economics theory of Kahneman into system 1 (fast and intuitive thinking) and system 2 (slow and cognitively demanding) or mixed (having elements of system 1 and system 2)...
September 10, 2018: Journal of Pediatrics
Emily B Heikamp, Ching-Hon Pui
No abstract text is available yet for this article.
September 10, 2018: Journal of Pediatrics
Rachel Kadakia, Denise M Scholtens, Gerald W Rouleau, Octavious Talbot, Olga R Ilkayeva, Tabitha George, Jami L Josefson
OBJECTIVE: To evaluate the association between cord blood amino acid and acylcarnitine profiles and measures of adiposity and hyperinsulinemia in healthy newborns. STUDY DESIGN: A cross-sectional study of 118 full-term infants born to mothers without gestational diabetes was performed. Cord blood leptin, C-peptide, acylcarnitine, and amino acid levels were measured. Body composition was measured by air displacement plethysmography. Multivariate linear regression and principal component analysis were used to analyze associations of cord blood metabolites with newborn anthropometrics, leptin, and C-peptide...
September 10, 2018: Journal of Pediatrics
Yi Zhong, Donna B Gilleskie, Miranda A L van Tilburg, Stephen R Hooper, Eniko Rak, Karina Javalkar, Meaghan Nazareth, Brian Pitts, Maggwa Ndugga, Nina Jain, Laura Hart, Suneet Bhansali, Jordan Richards, Randal K Detwiler, Karin True, Alexandre S F de Pomposo, Maria E Ferris
OBJECTIVE: To evaluate the roles of key individual, family, and illness characteristics on the levels of and gains in longitudinal healthcare transition (HCT) readiness in the pediatric setting and/or self-management skills (SMS) in the adult-focused setting, we used a large dataset with longitudinal measurements from 2006 to 2015. STUDY DESIGN: This longitudinal observational study followed 566 adolescents and young adults with chronic conditions at University of North Carolina Hospitals...
September 7, 2018: Journal of Pediatrics
Pieter Degraeuwe
No abstract text is available yet for this article.
September 7, 2018: Journal of Pediatrics
Sudeepta K Basu, Katherine Ottolini, Vedavalli Govindan, Suleiman Mashat, Gilbert Vezina, Yunfei Wang, Michaelande Ridore, Taeun Chang, Jeffrey R Kaiser, An N Massaro
OBJECTIVE: To investigate whether the early glycemic profile in infants with hypoxic ischemic encephalopathy is associated with distinct patterns of brain injury on magnetic resonance imaging (MRI). STUDY DESIGN: We performed a secondary analysis of 178 prospectively enrolled infants who received therapeutic hypothermia for hypoxic ischemic encephalopathy. Glycemic profiles were identified by glucose concentrations within 24 hours after birth: normoglycemia (all glucose concentrations of >47 to ≤150 mg/dL; n = 62); hypoglycemia (≥1 concentration ≤47 mg/dL; n = 17); hyperglycemia (≥1 concentration >150 mg/dL; n = 76); and labile glucose (both hypoglycemia and hyperglycemia; n = 23)...
September 6, 2018: Journal of Pediatrics
Julie D Flom, Yueh-Hsiu Mathilda Chiu, Hsiao-Hsien Leon Hsu, Katrina L Devick, Kelly J Brunst, Rebecca Campbell, Michelle Bosquet Enlow, Brent A Coull, Rosalind J Wright
OBJECTIVES: To evaluate associations between maternal lifetime traumatic stress and offspring birthweight and examine modifying effects of third trimester cortisol and fetal sex. STUDY DESIGN: Analyses included 314 mother-infant dyads from an ethnically mixed pregnancy cohort. Maternal lifetime trauma was reported via the Life Stressor Checklist-Revised. Fenton birthweight for gestational age z-scores (BWGA-z) were calculated. A 3-cm scalp-nearest maternal hair segment collected at birth was assayed to reflect cumulative third trimester cortisol secretion...
September 6, 2018: Journal of Pediatrics
Sarah Jane Schwarzenberg, Claudia K Fox
No abstract text is available yet for this article.
September 6, 2018: Journal of Pediatrics
Neil Patel, Anna Claudia Massolo, Anshuman Paria, Emily J Stenhouse, Lindsey Hunter, Emma Finlay, Carl F Davis
OBJECTIVE: To assess patterns of postnatal ventricular function and their relationship to prenatal and postnatal markers of disease severity in infants with congenital diaphragmatic hernia (CDH). STUDY DESIGN: In this observational case-control study of cardiac function in infants with CDH in the first 5 days of life, systolic and diastolic function in the right ventricle (RV) and left ventricle (LV) were assessed using speckle tracking echocardiography-derived global strain and tissue Doppler imaging...
September 6, 2018: Journal of Pediatrics
Prashant Mahajan, Lorin R Browne, Deborah A Levine, Daniel M Cohen, Rajender Gattu, James G Linakis, Jennifer Anders, Dominic Borgialli, Melissa Vitale, Peter S Dayan, T Charles Casper, Octavio Ramilo, Nathan Kuppermann
OBJECTIVE: To determine the risk of serious bacterial infections (SBIs) in young febrile infants with and without viral infections. STUDY DESIGN: Planned secondary analyses of a prospective observational study of febrile infants 60 days of age or younger evaluated at 1 of 26 emergency departments who did not have clinical sepsis or an identifiable site of bacterial infection. We compared patient demographics, clinical, and laboratory findings, and prevalence of SBIs between virus-positive and virus-negative infants...
September 6, 2018: Journal of Pediatrics
Richard J Schanler, Sharon L Groh-Wargo, Bridget Barrett-Reis, Robert D White, Kaashif A Ahmad, Jeffery Oliver, Geraldine Baggs, Larry Williams, David Adamkin
OBJECTIVE: To compare growth, feeding tolerance, and clinical and biochemical evaluations in human milk-fed preterm infants randomized to receive either an acidified or a nonacidified liquid human milk fortifier. STUDY DESIGN: This prospective, controlled, parallel, multicenter growth and tolerance study included 164 preterm infants (≤32 weeks of gestation, birth weight 700-1500 g) who were randomized to acidified or nonacidified liquid human milk fortifier from study day 1, the first day of fortification, through study day 29 or until hospital discharge...
September 5, 2018: Journal of Pediatrics
Philip Thaler Levy, Meghna D Patel, Gautam K Singh
No abstract text is available yet for this article.
September 5, 2018: Journal of Pediatrics
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