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Journal of Pediatrics

Nicholas M McCrory, Mathew J Edick, Ayesha Ahmad, Susan Lipinski, Jessica A Scott Schwoerer, Shaohui Zhai, Kaitlin Justice, Cynthia A Cameron, Susan A Berry, Loren D M Pena
OBJECTIVES: To compare time to evaluation and symptoms at diagnosis of propionic acidemia (PA) by method of ascertainment, and to explore correlations between genotype and biochemical variables. STUDY DESIGN: Clinical symptoms, genotype, and biochemical findings were analyzed retrospectively in 58 individuals with PA enrolled in the Inborn Errors of Metabolism Information System (IBEM-IS) based on the type of initial ascertainment: abnormal newborn screening (NBS), clinical presentation (symptomatic), or family history...
October 21, 2016: Journal of Pediatrics
Seetha Shankaran, Abbot R Laptook, Scott A McDonald, Susan R Hintz, Patrick D Barnes, Abhik Das, Rosemary D Higgins
: Infants with perinatal sentinel events in the Eunice Kennedy Shriver National Institute of Child Health and Human Development Neonatal Research Network Hypothermia for Encephalopathy Trial had more basal ganglia and thalamus lesions on brain magnetic resonance imaging but similar neurodevelopmental outcomes at 18 months of age than infants without perinatal sentinel events. Outcomes correlated with the neonatal magnetic resonance imaging findings. TRIAL REGISTRATION: ClinicalTrials...
October 21, 2016: Journal of Pediatrics
Radha Ram, Marissa D Marolf, Douglas P Marx, Richard M Braverman, Mihail Firan, Honey H Herce
No abstract text is available yet for this article.
October 21, 2016: Journal of Pediatrics
Jacquelyn M Powers, Mark Shamoun, Timothy L McCavit, Leah Adix, George R Buchanan
OBJECTIVE: To assess the benefits and risks of intravenous (IV) ferric carboxymaltose (FCM) in children with iron deficiency anemia (IDA). STUDY DESIGN: In a retrospective cohort study of patients seen at our center, we identified all FCM infusions in children with IDA over a 12-month period through a query of pharmacy records. Clinical data, including hematologic response and adverse effects, were extracted from the electronic medical record. RESULTS: A total of 116 IV FCM infusions were administered to 72 patients with IDA refractory to oral iron treatment (median age, 13...
October 21, 2016: Journal of Pediatrics
Paula Meier, Aloka Patel, Anita Esquerra-Zwiers
No abstract text is available yet for this article.
October 20, 2016: Journal of Pediatrics
Gabriela Albuquerque, Milton Severo, Andreia Oliveira
OBJECTIVE: To assess early life characteristics associated with appetite-related eating behaviors in 7-year-old children. STUDY DESIGN: The participants are children from the population-based birth cohort Generation XXI. Data on sociodemographics, health, and lifestyles and anthropometrics were collected at birth, and 4- and 7-year-old evaluations. A Portuguese version of the Children's Eating Behavior Questionnaire was completed by mothers (n = 3562 children) with children aged 7 years old...
October 18, 2016: Journal of Pediatrics
Colm R Breatnach, Orla Franklin, Naomi McCallion, Afif El-Khuffash
Systemic hypoperfusion secondary to a patent ductus arteriosus (PDA) is thought to only affect post-ductal vessels. In a prospective observational study of 51 preterm infants, we demonstrated that a persistent PDA by day 5-7 is associated with reversed diastolic flow in the brachiocephalic artery when compared with those without a PDA.
October 18, 2016: Journal of Pediatrics
Takahiro Aoki, Katsuyoshi Koh, Yuki Arakawa, Makiko Mori, Eiji Oguma, Ryoji Hanada
No abstract text is available yet for this article.
October 18, 2016: Journal of Pediatrics
Mark Brittan, Troy Richardson, Chén Kenyon, Marion Sills, Evan Fieldston, Matt Hall, David Fox, Samir Shah, Jay Berry
OBJECTIVES: To assess the relationships between postdischarge emergency department visits, oral corticosteroid (OCS) use, and 15- to 90-day asthma readmission in children. STUDY DESIGN: Retrospective study of 9288 children from 12 states in the Truven MarketScan Database, ages 2-18 years, hospitalized between January 1, 2009, and June 30, 2011, with asthma, and continuously enrolled in Medicaid for 6 months prior and 3 months after hospitalization. The primary outcome was 15- to 90-day readmission for asthma...
October 18, 2016: Journal of Pediatrics
Brett Keller, Andrew Faciano, Adey Tsega, Jacqueline Ehrlich
OBJECTIVES: To identify risk factors and describe outcomes for children newly identified with blood lead levels (BLLs) ≥45 µg/dL in New York City (NYC) during 2004-2010 to promote timely identification as well as inform clinical practice and public health policy. STUDY DESIGN: Inclusion criteria were residence in NYC and an elevated confirmatory venous test within 2 weeks of the initial BLL ≥45 µg/dL. Data collected during case coordination of these children were linked with blood testing data and home inspection reports...
October 14, 2016: Journal of Pediatrics
Maria Ubals, Anna Castany, Patricia Bassas, Jordi Mollet, Gloria Aparicio, Vicente García-Patos
No abstract text is available yet for this article.
October 14, 2016: Journal of Pediatrics
Isaac D Bleicher, Mays A El-Dairi
No abstract text is available yet for this article.
October 14, 2016: Journal of Pediatrics
Jamie Perin, Christine Marie George
No abstract text is available yet for this article.
October 14, 2016: Journal of Pediatrics
Matjaž Homan, Mario Poljak, Nina Zidar
No abstract text is available yet for this article.
October 14, 2016: Journal of Pediatrics
Luke Baertlein, Stephanie Yendell
No abstract text is available yet for this article.
October 13, 2016: Journal of Pediatrics
Eyal Sheiner, Tamar Wainstock, Daniella Landau, Asnat Walfisch
OBJECTIVE: To evaluate the association between sex and long-term pediatric cardiovascular morbidity. STUDY DESIGN: A population-based cohort study was performed that compared the risk of long-term cardiovascular morbidity (up to the age of 18 years) of children according to sex. Deliveries occurred between the years 1991 and 2013 in a tertiary medical center. Multiple pregnancies and fetal congenital malformations were excluded. Kaplan-Meier survival curves were constructed to compare cumulative cardiovascular morbidity incidence...
October 13, 2016: Journal of Pediatrics
Nicole S Glaser, Sandra L Wootton-Gorges, Isaac Kim, Daniel J Tancredi, James P Marcin, Andrew Muir, Nathan Kuppermann
OBJECTIVE: To characterize regional differences in brain water distribution and content during diabetic ketoacidosis (DKA) in children and determine whether these differences correlate with regional vascular supply. STUDY DESIGN: We compared changes in brain water distribution and water content in different brain regions during DKA by analyzing magnetic resonance diffusion weighted imaging data collected during DKA and after recovery in 45 children (<18 years of age)...
October 13, 2016: Journal of Pediatrics
Benjamin F Arnold
No abstract text is available yet for this article.
October 13, 2016: Journal of Pediatrics
Andrew O'Keefe, Ann Clarke, Yvan St Pierre, Jennifer Mill, Yuka Asai, Harley Eisman, Sebastien La Vieille, Reza Alizadehfar, Lawrence Joseph, Judy Morris, Jocelyn Graveli, Moshe Ben-Shoshan
OBJECTIVES: To determine the recurrence rate of anaphylaxis in children medically attended in an emergency department (ED), we performed a prospective cohort study to evaluate prehospital and ED management of children with recurrent anaphylaxis and to assess factors associated with recurrent anaphylaxis. STUDY DESIGN: As part of the Cross-Canada Anaphylaxis Registry, parents of children with anaphylaxis identified prospectively in 3 EDs and through an emergency medical response service were contacted annually after presentation and queried on subsequent reactions...
October 12, 2016: Journal of Pediatrics
Mattie F Wolf, Roshan P George, Barry Warshaw, Elizabeth Wang, Larry A Greenbaum
OBJECTIVES: To quantify physical activity and grip strength in pediatric kidney transplant recipients and describe attitudes about exercise and exercise counseling given concerns about allograft injury. STUDY DESIGN: This was a cross-sectional analysis of 101 kidney transplant recipients (7-21 years old) >6 months post-transplant. Patients completed the Physical Activity Questionnaire (PAQ). Grip strength was measured with a dynamometer. We asked about activity limitations and provider counseling...
October 11, 2016: Journal of Pediatrics
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