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Journal of Pediatrics

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https://www.readbyqxmd.com/read/28438377/efficacy-and-safety-of-lactobacillus-plantarum-dsm-9843-lp299v-in-the-prevention-of-antibiotic-associated-gastrointestinal-symptoms-in-children-randomized-double-blind-placebo-controlled-study
#1
Agnieszka Olek, Marek Woynarowski, Irini Lazou Ahrén, Jarosław Kierkuś, Piotr Socha, Niklas Larsson, Gunilla Önning
OBJECTIVES: To determine if Lactobacillus plantarum DSM9843 (LP299V) reduces the frequency of antibiotic-associated loose/watery stools and gastrointestinal symptoms, and can be administered safely to children who are prescribed antibiotics. STUDY DESIGN: We performed a prospective, double-blind, randomized, placebo-controlled, multicenter, parallel-group study in children receiving outpatient antibiotic therapy in primary healthcare settings. The children were given LP299V/placebo during the antibiotic therapy and for 1 week after the end of treatment...
April 21, 2017: Journal of Pediatrics
https://www.readbyqxmd.com/read/28438376/current-trends-in-the-use-of-two-combination-antifungal-corticosteroid-creams
#2
Chikoti M Wheat, Ryan J Bickley, Yu-Han Hsueh, Bernard A Cohen
Superficial fungal infections are among the most commonly managed skin problems by general practitioners. Although evidence shows combination antifungal/corticosteroid topicals are more expensive and less effective than single-agent antifungals, practitioners continue to prescribe combination agents. We examined current prescription trends of 2 combination antifungal/corticosteroid medications, Lotrisone and Mycolog-II.
April 21, 2017: Journal of Pediatrics
https://www.readbyqxmd.com/read/28438375/racial-and-ethnic-differences-in-pediatric-readmissions-for-common-chronic-conditions
#3
Kavita Parikh, Jay Berry, Matt Hall, Grant M Mussman, Amanda Montalbano, Joanna Thomson, Rustin Morse, Karen M Wilson, Samir S Shah
OBJECTIVE: To compare the timing and magnitude of variation of pediatric readmission rates across race/ethnicity for selected chronic conditions: asthma, diabetes, seizures, migraines, and depression. STUDY DESIGN: Retrospective analysis of hospitalizations at 48 children's hospitals in the 2013 Pediatric Health Information System database for children (ages 0-18 years) admitted for asthma (n = 36 910), seizure (n = 35 361), diabetes (n = 12 468), migraine (n = 5882), and depression (n = 5132)...
April 21, 2017: Journal of Pediatrics
https://www.readbyqxmd.com/read/28438374/validity-of-self-assessed-sexual-maturation-against-physician-assessments-and-hormone-levels
#4
Jorge E Chavarro, Deborah J Watkins, Myriam C Afeiche, Zhenzhen Zhang, Brisa N Sánchez, David Cantonwine, Adriana Mercado-García, Clara Blank-Goldenberg, John D Meeker, Martha María Téllez-Rojo, Karen E Peterson
OBJECTIVE: To compare self-report and physician assessments of sexual maturation against serum hormone markers to evaluate the hypothesis that the validity of self-assessed sexual maturation is underestimated in traditional validation studies. STUDY DESIGN: We adapted a self-assessment instrument that 248 Mexican children and adolescents, aged 8-13 years, completed. The participants were examined by a trained pediatrician and provided fasting blood samples for measurement of reproductive hormones (eg, testosterone, estradiol, sex hormone-binding globulin, inhibin B) and other hormones (eg, C-peptide, insulin-like growth factor 1, leptin, dehydroepiandrosterone sulfate) known to change during adolescence...
April 21, 2017: Journal of Pediatrics
https://www.readbyqxmd.com/read/28434554/the-simulation-based-assessment-of-pediatric-rapid-response-teams
#5
James J Fehr, Mary E McBride, John R Boulet, David J Murray
OBJECTIVE: To create scenarios of simulated decompensating pediatric patients to train pediatric rapid response teams (RRTs) and to determine whether the scenario scores provide a valid assessment of RRT performance with the hypothesis that RRTs led by intensivists-in-training would be better prepared to manage the scenarios than teams led by nurse practitioners. STUDY DESIGN: A set of 10 simulated scenarios was designed for the training and assessment of pediatric RRTs...
April 20, 2017: Journal of Pediatrics
https://www.readbyqxmd.com/read/28433203/the-limitations-of-transforming-very-high-body-mass-indexes-into-z-scores-among-8-7-million-2-to-4-year-old-children
#6
David S Freedman, Nancy F Butte, Elsie M Taveras, Alyson B Goodman, Cynthia L Ogden, Heidi M Blanck
OBJECTIVE: To examine the associations among several body mass index (BMI) metrics (z-scores, percent of the 95th percentile (%BMIp95) and BMI minus 95th percentile (ΔBMIp95) as calculated in the growth charts from the Centers for Disease Control and Prevention (CDC). It is known that the widely used BMI z-scores (BMIz) and percentiles calculated from the growth charts can differ substantially from those that directly observed in the data for BMIs above the 97th percentile (z = 1...
April 19, 2017: Journal of Pediatrics
https://www.readbyqxmd.com/read/28433202/tinea-faciei-challenges-in-the-diagnosis
#7
Tanvi Dev, Himabindu Saginatham, Gomathy Sethuraman
No abstract text is available yet for this article.
April 19, 2017: Journal of Pediatrics
https://www.readbyqxmd.com/read/28431746/re-evaluation-of-serum-ferritin-cut-off-values-for-the-diagnosis-of-iron-deficiency-in-children-aged-12-36-months
#8
Kawsari Abdullah, Catherine S Birken, Jonathon L Maguire, Darcy Fehlings, Anthony J Hanley, Kevin E Thorpe, Patricia C Parkin
An ongoing challenge has been determining clinically relevant serum ferritin cut-offs in the diagnosis of iron deficiency in children aged 1-3 years. We identified 2 potential clinically relevant serum ferritin cut-off values through their association with clinically important cut-off of hemoglobin as the indicator of anemia.
April 18, 2017: Journal of Pediatrics
https://www.readbyqxmd.com/read/28427778/factors-associated-with-delayed-presentation-and-misdiagnosis-of-testicular-torsion-a-case-control-study
#9
Christopher E Bayne, Jeffrey Villanueva, Tanya D Davis, Hans G Pohl, H G Rushton
We identified factors associated with delay in presentation and misdiagnosis of testicular torsion. Compared with acute cases, delayed presentations were more likely to report isolated abdominal pain, developmental disorders, and history of recent genital trauma. Failure to perform a genitourinary examination or scrotal imaging was associated with misdiagnosis.
April 18, 2017: Journal of Pediatrics
https://www.readbyqxmd.com/read/28427777/extrapontine-myelinolysis-in-a-child-with-salt-intoxication
#10
Janaki D Vakharia, Bracha Goldsweig, Jeffery M Rogg, Lisa Swartz Topor
No abstract text is available yet for this article.
April 18, 2017: Journal of Pediatrics
https://www.readbyqxmd.com/read/28416243/psychological-interventions-for-children-with-functional-somatic-symptoms-a-systematic-review-and-meta-analysis
#11
Irma J Bonvanie, Karen H Kallesøe, Karin A M Janssens, Andreas Schröder, Judith G M Rosmalen, Charlotte U Rask
OBJECTIVE: To analyze the effectiveness of psychological treatments on symptom load and associated disability in children with functional somatic symptoms, and to explore potential moderators of effects. STUDY DESIGN: Cochrane, PubMed, PsycINFO, EMBASE, and CINAHL were searched for randomized controlled trials published in peer-reviewed journals. Randomized controlled trials studying the effect of a psychological treatment on symptom load and disability in children with functional somatic symptoms were selected...
April 14, 2017: Journal of Pediatrics
https://www.readbyqxmd.com/read/28411949/reliability-of-echocardiographic-indicators-of-pulmonary-vascular-disease-in-preterm-infants-at-risk-for-bronchopulmonary-dysplasia
#12
Erin F Carlton, Marci K Sontag, Adel Younoszai, Michael V DiMaria, Joshua I Miller, Brenda B Poindexter, Steven H Abman, Peter M Mourani
OBJECTIVES: To determine the assessment and inter-rater reliability of echocardiographic evaluations of pulmonary vascular disease (PVD) in preterm infants at risk for bronchopulmonary dysplasia. STUDY DESIGN: We prospectively studied echocardiograms from preterm infants (birthweights 500-1250 g) at 7 days of age and 36 weeks postmenstrual age (PMA). Echocardiograms were assessed by both a cardiologist on clinical service and a single research cardiologist. Interpretations were reviewed for inclusion of determinants of PVD and assessed for inter-rater reliability using the Prevalence Adjusted Bias Adjusted Kappa Score (PABAK)...
April 12, 2017: Journal of Pediatrics
https://www.readbyqxmd.com/read/28410752/acute-liver-failure-secondary-to-neuroblastoma-amplified-sequence-deficiency
#13
Vanessa Cardenas, Frank DiPaola, Stacie D Adams, Alexander M Holtz, Ayesha Ahmad
No abstract text is available yet for this article.
April 12, 2017: Journal of Pediatrics
https://www.readbyqxmd.com/read/28408129/extra-octave-fracture-in-a-14-year-old-basketball-player
#14
Logan Mims, Morteza Khodaee
No abstract text is available yet for this article.
April 10, 2017: Journal of Pediatrics
https://www.readbyqxmd.com/read/28408128/health-disparities-in-the-appropriate-management-of-cryptorchidism
#15
Kate B Savoie, Marielena Bachier-Rodriguez, Elleson Schurtz, Elizabeth A Tolley, Dana Giel, Alexander Feliz
OBJECTIVE: To assess regional practices in management of cryptorchidism with regard to timely fixation by the current recommended age of 18 months. STUDY DESIGN: A retrospective study was performed. Charts of all patients who underwent surgical correction for cryptorchidism by a pediatric general surgeon or urologist within a tertiary pediatric hospital in an urban setting were systematically reviewed. RESULTS: We identified 1209 patients with cryptorchidism...
April 10, 2017: Journal of Pediatrics
https://www.readbyqxmd.com/read/28408127/double-ileoileal-intussusception-following-surgical-reduction-of-ileocolic-intussusception-in-an-8-month-old-female
#16
Hannah Jolley, Ashley M Gefen, Howard Ginsburg, Gabrielle Gold-von Simson
No abstract text is available yet for this article.
April 10, 2017: Journal of Pediatrics
https://www.readbyqxmd.com/read/28408126/high-risk-of-coronary-artery-aneurysms-in-infants-younger-than-6-months-of-age-with-kawasaki-disease
#17
Andrea P Salgado, Negar Ashouri, Erika K Berry, Xiaoying Sun, Sonia Jain, Jane C Burns, Adriana H Tremoulet
OBJECTIVES: To characterize the clinical presentation and outcome in infants <6 months of age with Kawasaki disease (KD) and to describe the use of newer anti-inflammatory therapies in this young population. STUDY DESIGN: We evaluated 88 infants <6 months old and 632 ≥6 months old treated for KD. We compared differences in laboratory data, response to treatment, and coronary artery outcomes between the 2 cohorts. Fisher exact test was used to analyze categorical variables, whereas the Wilcoxon rank sum test was used for continuous variables...
April 10, 2017: Journal of Pediatrics
https://www.readbyqxmd.com/read/28396031/penetrance-of-hypertrophic-cardiomyopathy-in-children-who-are-mutation-positive
#18
Alexa M C Vermeer, Sally-Ann B Clur, Nico A Blom, Arthur A M Wilde, Imke Christiaans
OBJECTIVES: To investigate the presence of hypertrophic cardiomyopathy (HCM) at first cardiac evaluation and during follow-up and cardiac events in predictively tested children who are mutation positive. STUDY DESIGN: The study included 119 predictively tested children who were mutation positive, with a mean age of 12.1 years. A family history and clinical variables from all cardiac evaluations after predictive genetic testing were recorded. Outcome measures were a clinical diagnosis of HCM, death, and cardiac events...
April 7, 2017: Journal of Pediatrics
https://www.readbyqxmd.com/read/28396030/automated-insulin-delivery-the-light-at-the-end-of-the-tunnel
#19
Kamuran Turksoy, Nicole Frantz, Laurie Quinn, Magdalena Dumin, Jennifer Kilkus, Brooks Hibner, Ali Cinar, Elizabeth Littlejohn
No abstract text is available yet for this article.
April 7, 2017: Journal of Pediatrics
https://www.readbyqxmd.com/read/28396029/parental-incarceration-and-child-sleep-and-eating-behaviors
#20
Dylan B Jackson, Michael G Vaughn
OBJECTIVES: To examine whether parental incarceration is significantly associated with a number of sleep and eating behaviors among offspring during early childhood. STUDY DESIGN: Data from the Fragile Families and Child Well-Being Study, an at-risk sample of parents and their offspring, were employed to test this possibility. Both maternal and paternal incarceration history were examined as predictors of whether children manifested high levels of the following 7 health behaviors: sleep problems, short sleep duration, salty snack consumption, starch consumption, sweets consumption, soda consumption, and fast food consumption...
April 7, 2017: Journal of Pediatrics
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