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Journal of Pediatrics

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https://www.readbyqxmd.com/read/28712521/subclinical-kidney-injury-in-children-receiving-nonsteroidal-anti-inflammatory-drugs-after-cardiac-surgery
#1
Edward Nehus, Ahmad Kaddourah, Michael Bennett, Olivia Pyles, Prasad Devarajan
OBJECTIVE: To investigate the association of nonsteroidal anti-inflammatory drug (NSAID) administration with urinary neutrophil gelatinase-associated lipocalin (NGAL) levels in children following cardiopulmonary bypass (CPB) who did not develop acute kidney injury (AKI). STUDY DESIGN: In this prospective observational study, urinary NGAL levels were investigated in 210 children who underwent cardiothoracic surgery requiring CPB. Children with clinical AKI (defined as an increase in serum creatinine ≥50% from baseline within 72 hours of CPB) were excluded from the analysis...
July 13, 2017: Journal of Pediatrics
https://www.readbyqxmd.com/read/28712520/rear-facing-car-safety-seat-use-for-children-18-months-of-age-prevalence-and-determinants
#2
Ashley T Jones, Benjamin D Hoffman, Adrienne R Gallardo, Tess A Gilbert, Kathleen F Carlson
OBJECTIVE: To examine the prevalence and potential determinants of rear-facing car safety seat use among children approximately 18 months of age born at a university hospital. STUDY DESIGN: We administered a telephone survey to caregivers of children 17-19 months of age who were born between November 2013 and May 2014. The survey was designed to assess the prevalence of rear-facing car safety seat use and estimate the likelihood of rear-facing car safety seat use, compared with forward-facing car seat use, in reference to hypothesized determinants...
July 13, 2017: Journal of Pediatrics
https://www.readbyqxmd.com/read/28712519/contemporary-outcomes-of-infants-with-gastroschisis-in-north-america-a-multicenter-cohort-study
#3
Brenna S Fullerton, Cristine S Velazco, Eric A Sparks, Kate A Morrow, Erika M Edwards, Roger F Soll, Biren P Modi, Jeffrey D Horbar, Tom Jaksic
OBJECTIVE: To quantify outcomes and analyze factors predictive of morbidity and mortality in infants with gastroschisis. STUDY DESIGN: Clinical data regarding neonates with gastroschisis born between 2009 and 2014 were prospectively collected at 175 North American centers. Multivariate regression was used to assess risk factors for mortality and length of stay (LOS). RESULTS: Gastroschisis was diagnosed in 4420 neonates with median birth weight 2410 g (IQR 2105-2747)...
July 13, 2017: Journal of Pediatrics
https://www.readbyqxmd.com/read/28712518/subclinical-atherosclerosis-in-youth-relation-to-obesity-insulin-resistance-and-polycystic-ovary-syndrome
#4
Brenda Mendizábal, Elaine M Urbina
No abstract text is available yet for this article.
July 13, 2017: Journal of Pediatrics
https://www.readbyqxmd.com/read/28712517/comparison-of-oropharyngeal-and-nasopharyngeal-swab-specimens-for-the-detection-of-mycoplasma-pneumoniae-in-children-with-lower-respiratory-tract-infection
#5
Fujio Kakuya, Takahiro Kinebuchi, Hitoshi Okubo, Kumihiro Matsuo
The oropharyngeal swab specimen was superior to the nasopharyngeal swab specimen for the detection of Mycoplasma pneumoniae in children with lower respiratory tract infection. The oropharyngeal loop-mediated isothermal amplification had 100% sensitivity and specificity compared with polymerase chain reaction testing, whereas the oropharyngeal rapid antigen detection test using immunochromatographic assay had relatively low sensitivity (66%) and reasonable specificity (90.7%).
July 13, 2017: Journal of Pediatrics
https://www.readbyqxmd.com/read/28712516/online-master-of-education-program-academic-outcomes
#6
EDITORIAL
Robert Harper, Lea Alaee, Jeanne R Spaulding, Thomas DeWitt, Melissa Klein
No abstract text is available yet for this article.
July 13, 2017: Journal of Pediatrics
https://www.readbyqxmd.com/read/28711176/biologic-agents-in-the-treatment-of-childhood-onset-rheumatic-disease
#7
Jay Mehta, Timothy Beukelman
No abstract text is available yet for this article.
July 13, 2017: Journal of Pediatrics
https://www.readbyqxmd.com/read/28711177/size-of-facial-port-wine-birthmark-may-predict-neurologic-outcome-in-sturge-weber-syndrome
#8
Malgorzata Dymerska, Anna Y Kirkorian, Elizabeth A Offermann, Doris D Lin, Anne M Comi, Bernard A Cohen
OBJECTIVE: To determine whether the size of the birthmark in patients with Sturge-Weber syndrome (SWS) who have brain involvement can help predict neurologic disability. STUDY DESIGN: Fifty-one patients with SWS with facial birthmarks and brain involvement documented on magnetic resonance imaging were included in this retrospective chart review. A neuroradiologist, blinded to all clinical information, assigned a previously validated SWS neuroimaging score. A pediatric neurologist prospectively assigned previously validated neurologic severity scores, based on seizures, hemiparesis, visual field cut, and cognitive impairments...
July 12, 2017: Journal of Pediatrics
https://www.readbyqxmd.com/read/28711175/the-prevalence-of-rome-iv-nonerosive-esophageal-phenotypes-in-children
#9
Lisa B Mahoney, Samuel Nurko, Rachel Rosen
OBJECTIVES: To assess the prevalence of Rome IV nonerosive esophageal phenotypes in children using multichannel intraluminal impedance testing and to describe the rates of proton pump inhibitor (PPI) responsiveness and the frequency of microscopic esophagitis in these patients. STUDY DESIGN: We conducted a retrospective review of all children ≥5 years of age who underwent esophagogastroduodenoscopy and multichannel intraluminal impedance testing off PPI therapy for evaluation of typical gastroesophageal reflux symptoms...
July 12, 2017: Journal of Pediatrics
https://www.readbyqxmd.com/read/28711174/secondhand-smoke-exposure-and-preclinical-markers-of-cardiovascular-risk-in-toddlers
#10
Judith A Groner, Hong Huang, Mandar S Joshi, Nicholas Eastman, Lisa Nicholson, John Anthony Bauer
OBJECTIVE: To investigate relationships between secondhand smoke exposure in young children and several preclinical markers of cardiovascular risk that have been established as relevant to adult populations. STUDY DESIGN: There were 139 children, 2-5 years of age, enrolled in a cross-sectional study. Secondhand smoke exposure was objectively determined by hair nicotine level; a comprehensive panel of clinical markers (morning blood pressure, fasting glucose and insulin, lipid profiles, inflammation) and research markers (markers of oxidation, endothelial stress, and endothelial repair) of cardiovascular risk status were assessed...
July 12, 2017: Journal of Pediatrics
https://www.readbyqxmd.com/read/28711173/presymptomatic-diagnosis-of-spinal-muscular-atrophy-through-newborn-screening
#11
Yin-Hsiu Chien, Shu-Chuan Chiang, Wen-Chin Weng, Ni-Chung Lee, Ching-Jie Lin, Wu-Shiun Hsieh, Wang-Tso Lee, Yuh-Jyh Jong, Tsang-Ming Ko, Wuh-Liang Hwu
OBJECTIVE: To demonstrate the feasibility of presymptomatic diagnosis of spinal muscular atrophy (SMA) through newborn screening (NBS). STUDY DESIGN: We performed a screening trial to assess all newborns who underwent routine newborn metabolic screening at the National Taiwan University Hospital newborn screening center between November 2014 and September 2016. A real-time polymerase chain reaction (RT-PCR) genotyping assay for the SMN1/SMN2 intron 7 c.888+100A/G polymorphism was performed to detect homozygous SMN1 deletion using dried blood spot (DBS) samples...
July 12, 2017: Journal of Pediatrics
https://www.readbyqxmd.com/read/28709634/examining-the-role-of-the-pediatric-emergency-department-in-reducing-unintended-adolescent-pregnancy
#12
Michelle Solomon, Gia M Badolato, Lauren S Chernick, Maria E Trent, James M Chamberlain, Monika K Goyal
OBJECTIVES: To determine pregnancy risk and receptiveness to emergency department (ED)-based pregnancy prevention interventions among adolescents accessing care in the ED. STUDY DESIGN: Cross-sectional electronic survey of adolescent females in a pediatric ED used to calculate the Pregnancy Risk Index, a validated measure estimating the annual risk of becoming pregnant based on recent sexual activity, contraceptive method(s), method-specific contraceptive failure rates, and interest in receipt of ED-based contraceptive services...
July 11, 2017: Journal of Pediatrics
https://www.readbyqxmd.com/read/28709633/treatment-and-nontreatment-of-the-patent-ductus-arteriosus-identifying-their-roles-in-neonatal-morbidity
#13
EDITORIAL
Ronald I Clyman, Melissa Liebowitz
No abstract text is available yet for this article.
July 11, 2017: Journal of Pediatrics
https://www.readbyqxmd.com/read/28709632/call-for-a-european-paediatric-association-union-of-national-european-paediatric-societies-and-associations-survey-on-national-child-health-care-services-for-european-children-with-malignancies
#14
EDITORIAL
Gerhard Gaedicke, Wibke Gronau, Holger Lode, Jochen Ehrich
No abstract text is available yet for this article.
July 11, 2017: Journal of Pediatrics
https://www.readbyqxmd.com/read/28709631/neurodevelopmental-profiles-of-children-with-congenital-heart-disease-at-school-age
#15
Nadja Naef, Rabia Liamlahi, Ingrid Beck, Vera Bernet, Hitendu Dave, Walter Knirsch, Beatrice Latal
OBJECTIVES: To assess 6-year neurodevelopmental outcomes in a current cohort of children with congenital heart disease (CHD) who underwent cardiopulmonary bypass surgery (CPB), and to determine risk factors for adverse outcomes. STUDY DESIGN: Outcomes were examined in 233 prospectively enrolled children with CHD (including 64 with a recognized genetic disorder) who underwent CPB between 2004 and 2009. Follow-up assessment included standardized neurologic, motor, and cognitive tests...
July 11, 2017: Journal of Pediatrics
https://www.readbyqxmd.com/read/28709630/validity-and-reliability-of-the-brazilian-version-of-the-weight-control-behaviors-scale
#16
Karin Louise Lenz Dunker, Angelica Medeiros Claudino
OBJECTIVE: To develop and validate the weight-control behaviors (WCBs) scale and to evaluate its psychometric properties. STUDY DESIGN: We made use of data from a cluster-randomized trial assessing the effectiveness of the Brazilian New Moves Program. The Brazilian New Moves Program was a multicomponent intervention aimed at preventing weight-related problems among adolescent girls in public schools in São Paulo, Brazil. RESULTS: Healthy and unhealthy WCBs were strongly associated...
July 11, 2017: Journal of Pediatrics
https://www.readbyqxmd.com/read/28709629/what-happens-to-blood-glucose-concentrations-after-oral-treatment-for-neonatal-hypoglycemia
#17
Deborah L Harris, Greg D Gamble, Philip J Weston, Jane E Harding
OBJECTIVE: To determine the change in blood glucose concentration after oral treatment of infants with hypoglycemia in the first 48 hours after birth. STUDY DESIGN: We analyzed data from 227 infants with hypoglycemia (blood glucose <46.8 mg/dL, 2.6 mmol/L) born at a tertiary hospital who experienced 295 episodes of hypoglycemia. Blood glucose concentrations were measured (glucose oxidase) within 90 minutes after randomization to dextrose or placebo gel plus feeding with formula, expressed breast milk, or breast feeding...
July 11, 2017: Journal of Pediatrics
https://www.readbyqxmd.com/read/28709628/prostaglandin-e1-induced-periostitis-and-reversibility-with-discontinuation
#18
Aditya Badheka, Pradeep Bangalore Prakash, Veerajalandhar Allareddy
No abstract text is available yet for this article.
July 11, 2017: Journal of Pediatrics
https://www.readbyqxmd.com/read/28705656/impact-of-enteroviral-polymerase-chain-reaction-testing-on-length-of-stay-for-infants-60-days-old-or-younger
#19
Paul L Aronson, Todd W Lyons, Andrea T Cruz, Stephen B Freedman, Pamela J Okada, Alesia H Fleming, Joseph L Arms, Amy D Thompson, Suzanne M Schmidt, Jeffrey Louie, Michael J Alfonzo, Michael C Monuteaux, Lise E Nigrovic
OBJECTIVE: To determine the impact of a cerebrospinal fluid enterovirus polymerase chain reaction (PCR) test performance on hospital length of stay (LOS) in a large multicenter cohort of infants undergoing evaluation for central nervous system infection. STUDY DESIGN: We performed a planned secondary analysis of a retrospective cohort of hospitalized infants ≤60 days of age who had a cerebrospinal fluid culture obtained at 1 of 18 participating centers (2005-2013)...
July 10, 2017: Journal of Pediatrics
https://www.readbyqxmd.com/read/28705655/twenty-five-year-survival-of-children-with-intellectual-disability-in-western-australia
#20
Jenny Bourke, Wendy N Nembhard, Kingsley Wong, Helen Leonard
OBJECTIVES: To investigate survival up to early adulthood for children with intellectual disability and compare their risk of mortality with that of children without intellectual disability. STUDY DESIGN: This was a retrospective cohort study of all live births in Western Australia between January 1, 1983 and December 31, 2010. Children with an intellectual disability (n = 10 593) were identified from the Western Australian Intellectual Disability Exploring Answers Database...
July 10, 2017: Journal of Pediatrics
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