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Journal of Neurology, Neurosurgery, and Psychiatry

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https://www.readbyqxmd.com/read/29777012/prodromal-muscle-cramps-predict-rapid-motor-functional-decline-in-amyotrophic-lateral-sclerosis
#1
LETTER
Kazumoto Shibuya, Sonoko Misawa, Yukari Sekiguchi, Minako Beppu, Hiroshi Amino, Tomoki Suichi, Yo-Ichi Suzuki, Atsuko Tsuneyama, Satoshi Kuwabara
No abstract text is available yet for this article.
May 18, 2018: Journal of Neurology, Neurosurgery, and Psychiatry
https://www.readbyqxmd.com/read/29769251/systematic-review-and-network-meta-analysis-of-resective-surgery-for-mesial-temporal-lobe-epilepsy
#2
Puneet Jain, George Tomlinson, Carter Snead, Beate Sander, Elysa Widjaja
OBJECTIVE: To evaluate the effectiveness of anterior temporal lobectomy (ATL) versus selective amygdalohippocampectomy (SAH) on seizure-free outcome in patients with temporal lobe epilepsy, using both direct and indirect evidence from the literature. METHODS: MEDLINE, Embase and Cochrane databases were searched for original research articles and systematic reviews comparing ATL versus SAH, and ATL or SAH versus medical management (MM). The outcome was seizure freedom at 12 months of follow-up or longer...
May 16, 2018: Journal of Neurology, Neurosurgery, and Psychiatry
https://www.readbyqxmd.com/read/29769250/acetazolamide-can-improve-symptoms-and-signs-in-ion-channel-related-congenital-myopathy
#3
LETTER
Emma Matthews, Louise Hartley, Richa Sud, Michael G Hanna, Francesco Muntoni, Pinki Munot
No abstract text is available yet for this article.
May 16, 2018: Journal of Neurology, Neurosurgery, and Psychiatry
https://www.readbyqxmd.com/read/29764926/search-for-a-prognostic-biomarker-in-multiple-sclerosis-a-step-in-the-right-direction
#4
EDITORIAL
Bruce V Taylor
No abstract text is available yet for this article.
May 15, 2018: Journal of Neurology, Neurosurgery, and Psychiatry
https://www.readbyqxmd.com/read/29743290/cerebrospinal-fluid-immunoglobulin-light-chain-ratios-predict-disease-progression-in-multiple-sclerosis
#5
Emma Rathbone, Lindsay Durant, James Kinsella, Antony R Parker, Ghaniah Hassan-Smith, Michael R Douglas, S John Curnow
OBJECTIVE: To determine whether the ratio of cerebrospinal fluid (CSF) immunoglobulin kappa to lambda light chains at time of multiple sclerosis (MS) diagnosis predicts disease progression and whether this was intrinsic to CSF plasmablasts. METHODS: CSF and peripheral blood were obtained from patients undergoing elective diagnostic lumbar puncture and included clinically isolated syndrome (CIS) (n=43), relapsing remitting MS (RRMS; n=50), primary progressive MS (PPMS; n=20) and other neurological disease controls, both inflammatory (ONID; n=23) and non-inflammatory (OND; n=114)...
May 9, 2018: Journal of Neurology, Neurosurgery, and Psychiatry
https://www.readbyqxmd.com/read/29735516/adolescent-brain-development-and-gender-predictors-of-future-reading-habits
#6
Clare Elizabeth Caldwell
No abstract text is available yet for this article.
May 7, 2018: Journal of Neurology, Neurosurgery, and Psychiatry
https://www.readbyqxmd.com/read/29735515/perifocal-metabolism-in-a-patient-with-brain-abscess-insights-from-cerebral-microdialysis
#7
LETTER
Verena Rass, Mario Kofler, Alois J Schiefecker, Max Gaasch, Claudia Unterhofer, Claudius Thomé, Paul Rhomberg, Bettina Pfausler, Ronny Beer, Erich Schmutzhard, Raimund Helbok
No abstract text is available yet for this article.
May 7, 2018: Journal of Neurology, Neurosurgery, and Psychiatry
https://www.readbyqxmd.com/read/29735514/paradox-of-amyotrophic-lateral-sclerosis-and-energy-metabolism
#8
EDITORIAL
Rebekah M Ahmed, Luc Dupuis, Matthew C Kiernan
No abstract text is available yet for this article.
May 7, 2018: Journal of Neurology, Neurosurgery, and Psychiatry
https://www.readbyqxmd.com/read/29735513/a-unifying-theory-for-cognitive-abnormalities-in-functional-neurological-disorders-fibromyalgia-and-chronic-fatigue-syndrome-systematic-review
#9
REVIEW
Tiago Teodoro, Mark J Edwards, Jeremy D Isaacs
BACKGROUND: Functional cognitive disorder (FCD) describes cognitive dysfunction in the absence of an organic cause. It is increasingly prevalent in healthcare settings yet its key neuropsychological features have not been reported in large patient cohorts. We hypothesised that cognitive profiles in fibromyalgia (FM), chronic fatigue syndrome (CFS) and functional neurological disorders (FNDs) would provide a template for characterising FCD. METHODS: We conducted a systematic review of studies with cognition-related outcomes in FM, CFS and FND...
May 7, 2018: Journal of Neurology, Neurosurgery, and Psychiatry
https://www.readbyqxmd.com/read/29735512/cognitive-behavioural-therapy-does-not-meaningfully-reduce-depression-in-most-people-with-epilepsy-a-systematic-review-of-clinically-reliable-improvement
#10
REVIEW
Adam J Noble, James Reilly, James Temple, Peter L Fisher
Psychological treatment is recommended for depression and anxiety in those with epilepsy. This review used standardised criteria to evaluate, for the first time, the clinical relevance of any symptom change these treatments afford patients. Databases were searched until March 2017 for relevant trials in adults. Trial quality was assessed and trial authors asked for individual participants' pre-treatment and post-treatment distress data. Jacobson's methodology determined the proportion in the different trial arms demonstrating reliable symptom change on primary and secondary outcome measures and its direction...
May 7, 2018: Journal of Neurology, Neurosurgery, and Psychiatry
https://www.readbyqxmd.com/read/29735511/muscle-mri-in-patients-with-dysferlinopathy-pattern-recognition-and-implications-for-clinical-trials
#11
Jordi Diaz-Manera, Roberto Fernandez-Torron, Jaume LLauger, Meredith K James, Anna Mayhew, Fiona E Smith, Ursula R Moore, Andrew M Blamire, Pierre G Carlier, Laura Rufibach, Plavi Mittal, Michelle Eagle, Marni Jacobs, Tim Hodgson, Dorothy Wallace, Louise Ward, Mark Smith, Roberto Stramare, Alessandro Rampado, Noriko Sato, Takeshi Tamaru, Bruce Harwick, Susana Rico Gala, Suna Turk, Eva M Coppenrath, Glenn Foster, David Bendahan, Yann Le Fur, Stanley T Fricke, Hansel Otero, Sheryl L Foster, Anthony Peduto, Anne Marie Sawyer, Heather Hilsden, Hanns Lochmuller, Ulrike Grieben, Simone Spuler, Carolina Tesi Rocha, John W Day, Kristi J Jones, Diana X Bharucha-Goebel, Emmanuelle Salort-Campana, Matthew Harms, Alan Pestronk, Sabine Krause, Olivia Schreiber-Katz, Maggie C Walter, Carmen Paradas, Jean-Yves Hogrel, Tanya Stojkovic, Shin'ichi Takeda, Madoka Mori-Yoshimura, Elena Bravver, Susan Sparks, Luca Bello, Claudio Semplicini, Elena Pegoraro, Jerry R Mendell, Kate Bushby, Volker Straub
BACKGROUND AND OBJECTIVE: Dysferlinopathies are a group of muscle disorders caused by mutations in the DYSF gene. Previous muscle imaging studies describe a selective pattern of muscle involvement in smaller patient cohorts, but a large imaging study across the entire spectrum of the dysferlinopathies had not been performed and previous imaging findings were not correlated with functional tests. METHODS: We present cross-sectional T1-weighted muscle MRI data from 182 patients with genetically confirmed dysferlinopathies...
May 7, 2018: Journal of Neurology, Neurosurgery, and Psychiatry
https://www.readbyqxmd.com/read/29706605/hypermetabolism-in-als-is-associated-with-greater-functional-decline-and-shorter-survival
#12
Frederik J Steyn, Zara A Ioannides, Ruben P A van Eijk, Susan Heggie, Kathryn A Thorpe, Amelia Ceslis, Saman Heshmat, Anjali K Henders, Naomi R Wray, Leonard H van den Berg, Robert D Henderson, Pamela A McCombe, Shyuan T Ngo
OBJECTIVE: To determine the prevalence of hypermetabolism, relative to body composition, in amyotrophic lateral sclerosis (ALS) and its relationship with clinical features of disease and survival. METHODS: Fifty-eight patients with clinically definite or probable ALS as defined by El Escorial criteria, and 58 age and sex-matched control participants underwent assessment of energy expenditure. Our primary outcome was the prevalence of hypermetabolism in cases and controls...
April 29, 2018: Journal of Neurology, Neurosurgery, and Psychiatry
https://www.readbyqxmd.com/read/29705720/o-2-18-f-fluoroethyl-l-tyrosine-pet-for-the-differentiation-of-tumour-recurrence-from-late-pseudoprogression-in-glioblastoma
#13
LETTER
Milena I Mihovilovic, Olivia Kertels, Heribert Hänscheid, Mario Löhr, Camelia-Maria Monoranu, Irene Kleinlein, Samuel Samnick, Almuth F Kessler, Thomas Linsenmann, Ralf-Ingo Ernestus, Andreas K Buck, Constantin Lapa
No abstract text is available yet for this article.
April 28, 2018: Journal of Neurology, Neurosurgery, and Psychiatry
https://www.readbyqxmd.com/read/29685900/physical-activity-as-a-risk-factor-in-als
#14
EDITORIAL
Michael Swash
No abstract text is available yet for this article.
April 23, 2018: Journal of Neurology, Neurosurgery, and Psychiatry
https://www.readbyqxmd.com/read/29685899/multicentre-cross-cultural-population-based-case-control-study-of-physical-activity-as-risk-factor-for-amyotrophic-lateral-sclerosis
#15
Anne E Visser, James P K Rooney, Fabrizio D'Ovidio, Henk-Jan Westeneng, Roel C H Vermeulen, Ettore Beghi, Adriano Chiò, Giancarlo Logroscino, Orla Hardiman, Jan H Veldink, Leonard H van den Berg
OBJECTIVE: To investigate the association between physical activity (PA) and amyotrophic lateral sclerosis (ALS) in population-based case-control studies in three European countries using a validated and harmonised questionnaire. METHODS: Patients with incident ALS and controls were recruited from five population-based registers in The Netherlands, Ireland and Italy. Demographic and data regarding educational level, smoking, alcohol habits and lifetime PA levels in both leisure and work time were gathered by questionnaire, and quantified using metabolic equivalent of task scores...
April 23, 2018: Journal of Neurology, Neurosurgery, and Psychiatry
https://www.readbyqxmd.com/read/29680791/central-nervous-system-in-motor-neuron-disease
#16
Andrew Eisen
No abstract text is available yet for this article.
April 21, 2018: Journal of Neurology, Neurosurgery, and Psychiatry
https://www.readbyqxmd.com/read/29674479/regionally-clustered-abcc8-polymorphisms-in-a-prospective-cohort-predict-cerebral-oedema-and-outcome-in-severe-traumatic-brain-injury
#17
Ruchira Menka Jha, Theresa A Koleck, Ava M Puccio, David O Okonkwo, Seo-Young Park, Benjamin E Zusman, Robert S B Clark, Lori A Shutter, Jessica S Wallisch, Philip E Empey, Patrick M Kochanek, Yvette P Conley
OBJECTIVE: ABCC8 encodes sulfonylurea receptor 1, a key regulatory protein of cerebral oedema in many neurological disorders including traumatic brain injury (TBI). Sulfonylurea-receptor-1 inhibition has been promising in ameliorating cerebral oedema in clinical trials. We evaluated whether ABCC8 tag single-nucleotide polymorphisms predicted oedema and outcome in TBI. METHODS: DNA was extracted from 485 prospectively enrolled patients with severe TBI. 410 were analysed after quality control...
April 19, 2018: Journal of Neurology, Neurosurgery, and Psychiatry
https://www.readbyqxmd.com/read/29666209/lesion-site-dependent-responses-to-therapy-after-aphasic-stroke
#18
LETTER
Oscar M Aguilar, Sheila J Kerry, Yean-Hoon Ong, Martina F Callaghan, Jennifer Crinion, Zoe Victoria Joan Woodhead, Cathy J Price, Alexander P Leff, Thomas M H Hope
No abstract text is available yet for this article.
April 17, 2018: Journal of Neurology, Neurosurgery, and Psychiatry
https://www.readbyqxmd.com/read/29666208/insights-into-parkinson-s-disease-from-computational-models-of-the-basal-ganglia
#19
REVIEW
Mark D Humphries, Jose Angel Obeso, Jakob Kisbye Dreyer
Movement disorders arise from the complex interplay of multiple changes to neural circuits. Successful treatments for these disorders could interact with these complex changes in myriad ways, and as a consequence their mechanisms of action and their amelioration of symptoms are incompletely understood. Using Parkinson's disease as a case study, we review here how computational models are a crucial tool for taming this complexity, across causative mechanisms, consequent neural dynamics and treatments. For mechanisms, we review models that capture the effects of losing dopamine on basal ganglia function; for dynamics, we discuss models that have transformed our understanding of how beta-band (15-30 Hz) oscillations arise in the parkinsonian basal ganglia...
April 17, 2018: Journal of Neurology, Neurosurgery, and Psychiatry
https://www.readbyqxmd.com/read/29666207/split-hand-muscle-echo-intensity-index-as-a-reliable-imaging-marker-for-differential-diagnosis-of-amyotrophic-lateral-sclerosis
#20
Hung Youl Seok, Jinseok Park, Yoo Hwan Kim, Ki-Wook Oh, Seung Hyun Kim, Byung-Jo Kim
OBJECTIVE: The objective of this study was to investigate the usefulness of muscle ultrasound in evaluating dissociated small hand muscle atrophy, termed 'split hand', and its feasibility in the diagnosis of amyotrophic lateral sclerosis (ALS). METHODS: Forty-four patients with ALS, 18 normal subjects and 9 patients with other neuromuscular disorders were included in this study. The hand muscles were divided into three regions, the median-innervated lateral hand muscle group (ML), the ulnar-innervated lateral hand muscle (UL) and the ulnar-innervated medial hand muscle (UM), and the muscle echo intensity (EI) and compound muscle action potential (CMAP) were measured...
April 17, 2018: Journal of Neurology, Neurosurgery, and Psychiatry
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