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Journal of Heart and Lung Transplantation

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https://www.readbyqxmd.com/read/29426715/the-first-step-of-a-long-journey-effect-of-induction-regimen-on-prognosis-among-simultaneous-heart-kidney-transplant-recipients
#1
EDITORIAL
Avishay Grupper
No abstract text is available yet for this article.
February 2, 2018: Journal of Heart and Lung Transplantation
https://www.readbyqxmd.com/read/29452978/the-management-of-antibodies-in-heart-transplantation-an-ishlt-consensus-document
#2
Jon Kobashigawa, Monica Colvin, Luciano Potena, Duska Dragun, Maria G Crespo-Leiro, Juan F Delgado, Michael Olymbios, Jayan Parameshwar, Jignesh Patel, Elaine Reed, Nancy Reinsmoen, E Rene Rodriguez, Heather Ross, Randall C Starling, Dolly Tyan, Simon Urschel, Andreas Zuckermann
Despite the successes from refined peri-operative management techniques and immunosuppressive therapies, antibodies remain a serious cause of morbidity and mortality for patients both before and after heart transplantation. Patients awaiting transplant who possess antibodies against human leukocyte antigen are disadvantaged by having to wait longer to receive an organ from a suitably matched donor. The number of pre-sensitized patients has been increasing, a trend that is likely due to the increased use of mechanical circulatory support devices...
January 31, 2018: Journal of Heart and Lung Transplantation
https://www.readbyqxmd.com/read/29449075/cardiac-transplantation-in-children-with-down-syndrome-turner-syndrome-and-other-chromosomal-anomalies-a-multi-institutional-outcomes-analysis
#3
Christopher R Broda, Antonio G Cabrera, Joseph W Rossano, John L Jefferies, Jeffrey A Towbin, Clifford Chin, Pirouz Shamszad
BACKGROUND: The purpose of this study was to describe the prevalence, characteristics, and outcomes in pediatric patients with chromosomal anomalies (CA) undergoing orthotopic heart transplantation (OHT). METHODS: A query of the database of the Pediatric Health Information System, a large administrative and billing database of 43 tertiary children's hospitals, was performed for the Years 2004 to 2016. Pediatric patients who received OHT were analyzed based on presence and type of CA...
January 31, 2018: Journal of Heart and Lung Transplantation
https://www.readbyqxmd.com/read/29428317/don-t-worry-be-happy-with-intravenous-norepinephrine
#4
EDITORIAL
Maria Rosa Costanzo
No abstract text is available yet for this article.
January 31, 2018: Journal of Heart and Lung Transplantation
https://www.readbyqxmd.com/read/29398282/dr-michael-peter-kaye
#5
EDITORIAL
Stuart Jamieson
No abstract text is available yet for this article.
January 31, 2018: Journal of Heart and Lung Transplantation
https://www.readbyqxmd.com/read/29395751/early-stroke-post-heart-transplant-is-associated-with-decreased-survival-in-children
#6
Cheryl Cammock, Swati Choudhry, Chesney M Castleberry, Noor Al-Hammadi, Pirooz Eghtesady, Charles E Canter, Kathleen E Simpson
BACKGROUND: Major neurologic events (MNEs) after heart transplantation (HTx) and their effect on survival have not been well described in children. In this study we aimed to characterize early MNEs (stroke, isolated seizures not from stroke and posterior reversible leukoencephalopathy [PRES] within 1 year after primary pediatric HTx) and evaluate their impact on 1-year post-HTx survival. We hypothesized that early an MNE after HTx is associated with decreased 1-year patient survival. METHODS: We performed a pediatric, single-center, retrospective analysis of 345 consecutive patients aged 0 to 22 years who underwent primary HTx during the period from November 1, 1994 to October 31, 2015...
January 9, 2018: Journal of Heart and Lung Transplantation
https://www.readbyqxmd.com/read/29395753/authors-reply-to-hadid-and-colleagues-comment-on-catheter-ablation-of-atrial-flutter-following-orthotopic-heart-transplantation
#7
LETTER
Yamina Mouhoub, Mikael Laredo, Guillaume Duthoit
No abstract text is available yet for this article.
December 24, 2017: Journal of Heart and Lung Transplantation
https://www.readbyqxmd.com/read/29402604/limited-usefulness-of-endoscopic-evaluation-in-patients-with-continuous-flow-left-ventricular-assist-devices-and-gastrointestinal-bleeding
#8
Jordan E Axelrad, Alberto Pinsino, Pauline N Trinh, Anusorn Thanataveerat, Christian Brooks, Ryan T Demmer, Lisa Effner, Grant Parkis, Barbara Cagliostro, Jiho Han, A Reshad Garan, Veli Topkara, Koji Takeda, Hiroo Takayama, Yoshifumi Naka, Ivonne Ramirez, Reuben Garcia-Carrasquillo, Paolo C Colombo, Tamas Gonda, Melana Yuzefpolskaya
BACKGROUND: Gastrointestinal bleeding (GIB) is a frequent cause of re-admission in patients with continuous-flow left ventricular assist devices (CF-LVADs) and is associated with multiple endoscopic procedures and high resource utilization. Our aim was to determine the diagnostic and therapeutic yield of endoscopy and to develop a more cost-effective approach for the management of GIB in CF-LVAD recipients. METHODS: We retrospectively reviewed 428 patients implanted with a CF-LVAD between 2009 and 2016 at the Columbia University Medical Center and identified those hospitalized for GIB...
December 20, 2017: Journal of Heart and Lung Transplantation
https://www.readbyqxmd.com/read/29398281/neurocognitive-outcomes-after-heart-transplantation-in-early-childhood
#9
Simon Urschel, Gwen Y Bond, Irina A Dinu, Fahime Moradi, Jennifer Conway, Gonzalo Garcia-Guerra, Bryan V Acton, Ari R Joffe, Mohammed AlAklabi, Ivan M Rebeyka, Charlene M T Robertson
BACKGROUND: Children requiring heart transplantation (HTx) for congenital heart disease (CHD) or failing anatomically normal hearts (CMP) face different challenges pre-HTx. We compared the neurocognitive capabilities in pre-school-age children receiving HTx for CHD vs CMP and determined factors predicting outcomes. METHODS: Data were collected within a prospective multi-provincial project from children who underwent HTx ≤4 years of age between 1999 and 2011. At age 54 ± 3 months, we obtained scores from the Wechsler Preschool and Primary Scales of Intelligence for full-scale intelligence quotient (FSIQ) verbal intelligence quotient (VIQ) and performance intelligence quotient (PIQ), and from the Beery-Buktenica Developmental Test for visual-motor integration (VMI)...
December 20, 2017: Journal of Heart and Lung Transplantation
https://www.readbyqxmd.com/read/29397284/preservation-of-conductive-propagation-after-surgical-repair-of-cardiac-defects-with-a-bio-engineered-conductive-patch
#10
Sheng He, Huifang Song, Jun Wu, Shu-Hong Li, Richard D Weisel, Hsing-Wen Sung, Jianding Li, Ren-Ke Li
BACKGROUND: Both stable and biodegradable biomaterials have been used to surgically repair congenital cardiac defects. However, neither type of biomaterial can conduct electrical activity. We evaluated the conductivity and efficacy of a newly synthesized conductive polypyrrole-chitosan (Ppy+Chi) gelfoam patch to support cardiomyocyte (CM) viability and function in vitro and to surgically repair a cardiac defect in vivo. METHODS: Ppy+Chi was incorporated into gelfoam (Gel) to form a 3-dimensional conductive patch...
December 20, 2017: Journal of Heart and Lung Transplantation
https://www.readbyqxmd.com/read/29395752/disclosure-of-infectious-risk-to-heart-transplant-candidates-shared-decision-making-is-here-to-stay
#11
EDITORIAL
Yasbanoo Moayedi, Heather J Ross, Kiran K Khush
The Public Health Service has defined 12 criteria of increased-risk (PHS-IR) for transmissible viral infections in potential organ donors where clinicians are required to document informed consent. Over the last decade, there has been a near tripling of PHS-IR donor organs in the United States. In light of the paucity in guidelines and consensus statements to guide clinicians on how to provide informed consent to potential recipients, using a typical case, we provide an overview including: how to effectively communicate infectious risk, whether clinicians should decline PHS-IR organs, the need to standardize disclosure practice across centers and finally how much information about the donor should be communicated to the transplant candidate...
December 20, 2017: Journal of Heart and Lung Transplantation
https://www.readbyqxmd.com/read/29370971/high-dose-catecholamine-donor-support-and-outcomes-after-heart-transplantation
#12
Philipp Angleitner, Alexandra Kaider, Johannes Gökler, Roxana Moayedifar, Emilio Osorio-Jaramillo, Andreas Zuckermann, Günther Laufer, Arezu Aliabadi-Zuckermann
BACKGROUND: Higher dose norepinephrine donor support is a frequent reason for donor heart decline, but its associations with outcomes after heart transplantation are unclear. METHODS: We retrospectively analyzed 965 patients transplanted between 1992 and 2015 in the Heart Transplant Program Vienna. Stratification was performed according to donor norepinephrine dose administered before organ procurement (Group 0: 0 µg/kg/min; Group 1: 0.01 to 0.1 µg/kg/min; Group 2: >0...
December 20, 2017: Journal of Heart and Lung Transplantation
https://www.readbyqxmd.com/read/29370970/association-of-long-pentraxin-3-with-pulmonary-hypertension-and-primary-graft-dysfunction-in-lung-transplant-recipients
#13
LETTER
Joshua M Diamond, Kristy Ramphal, Mary K Porteous, Edward Cantu, Jason D Christie, Steven M Kawut
No abstract text is available yet for this article.
December 20, 2017: Journal of Heart and Lung Transplantation
https://www.readbyqxmd.com/read/29358011/from-6-years-to-5-days-for-organ-allocation-policy-change
#14
LETTER
Thomas M Egan
No abstract text is available yet for this article.
December 20, 2017: Journal of Heart and Lung Transplantation
https://www.readbyqxmd.com/read/29373179/post-transplant-outcomes-in-pediatric-ventricular-assist-device-patients-a-pedimacs-pediatric-heart-transplant-study-linkage-analysis
#15
David L Sutcliffe, Elizabeth Pruitt, Ryan S Cantor, Justin Godown, John Lane, Mark W Turrentine, Sabrina P Law, Jodie L Lantz, James K Kirklin, Daniel Bernstein, Elizabeth D Blume
BACKGROUND: Pediatric ventricular assist device (VAD) support as bridge to transplant has improved waitlist survival, but the effects of pre-implant status and VAD-related events on post-transplant outcomes have not been assessed. This study is a linkage analysis between the PediMACS and Pediatric Heart Transplant Study databases to determine the effects of VAD course on post-transplant outcomes. METHODS: Database linkage between October 1, 2012 and December 31, 2015 identified 147 transplanted VAD patients, the primary study group...
December 13, 2017: Journal of Heart and Lung Transplantation
https://www.readbyqxmd.com/read/29248336/erratum
#16
(no author information available yet)
No abstract text is available yet for this article.
December 13, 2017: Journal of Heart and Lung Transplantation
https://www.readbyqxmd.com/read/29426716/utility-of-troponin-assays-for-exclusion-of-acute-cellular-rejection-after-heart-transplantation-a-systematic-review
#17
Sarah Fitzsimons, Jonathan Evans, Jayan Parameshwar, Stephen J Pettit
BACKGROUND: Acute cellular rejection (ACR) is a common complication in the first year after heart transplantation (HT). Routine surveillance for ACR is undertaken by endomyocardial biopsy (EMB). Measurement of cardiac troponins (cTn) in serum is an established diagnostic test of cardiac myocyte injury. This systematic review aimed to determine whether cTn measurement could be used to diagnose or exclude ACR. METHODS: PubMed, Google Scholar and the JHLT archive were searched for studies reporting the result of a cTn assay and a paired surveillance EMB...
December 11, 2017: Journal of Heart and Lung Transplantation
https://www.readbyqxmd.com/read/29329761/n-terminal-pro-b-type-natriuretic-peptide-for-monitoring-after-balloon-pulmonary-angioplasty-for-chronic-thromboembolic-pulmonary-hypertension
#18
Steffen D Kriechbaum, Christoph B Wiedenroth, Jan Sebastian Wolter, Regula Hütz, Moritz Haas, Andreas Breithecker, Fritz C Roller, Till Keller, Stefan Guth, Andreas Rolf, Christian W Hamm, Eckhard Mayer, Christoph Liebetrau
BACKGROUND: Balloon pulmonary angioplasty (BPA) is an emerging interventional treatment option for chronic thromboembolic pulmonary hypertension (CTEPH). The non-invasive monitoring of CTEPH patients is a clinical challenge. In this study we examined changes in N-terminal pro-B-type natriuretic peptide (NT-proBNP) in patients undergoing BPA for inoperable CTEPH and related them to peri-procedural success. METHODS: In this study we analyzed a total of 51 consecutive patients who underwent BPA treatment and completed a 6-month follow-up (6-MFU) between March 2014 and March 2017...
December 8, 2017: Journal of Heart and Lung Transplantation
https://www.readbyqxmd.com/read/29275844/left-ventricular-assist-devices-versus-medical-management-in-ambulatory-heart-failure-patients-an-analysis-of-intermacs-profiles-4-and-5-to-7-from-the-roadmap-study
#19
Keyur B Shah, Randall C Starling, Joseph G Rogers, Douglas A Horstmanshof, James W Long, Vigneshwar Kasirajan, Josef Stehlik, Joyce Chuang, David J Farrar, Jerry D Estep
BACKGROUND: The ROADMAP study showed survival with improved functional status was better with left ventricular assist device (LVAD) therapy compared with optimal medical management (OMM) in ambulatory, non-inotrope-dependent (INTERMACS [IM] Profile 4 to 7) patients. To study more balanced cohorts and better define which patients may benefit from implantation of an LVAD, we re-evaluated the patients enrolled in ROADMAP when stratified by INTERMACS profile (Profile 4 and Profiles 5 to 7)...
December 7, 2017: Journal of Heart and Lung Transplantation
https://www.readbyqxmd.com/read/29275142/isolated-hyperammonemic-encephalopathy-in-heart-transplantation
#20
LETTER
Ronson J Madathil, Lauren G Gilstrap, Marc P Pelletier, Mandeep R Mehra
No abstract text is available yet for this article.
December 7, 2017: Journal of Heart and Lung Transplantation
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