journal
MENU ▼
Read by QxMD icon Read
search

Journal of Heart and Lung Transplantation

journal
https://www.readbyqxmd.com/read/29802086/uric-acid-is-an-independent-predictor-of-cardiac-allograft-vasculopathy-after-heart-transplantation
#1
Rabea Asleh, Megha Prasad, Alexandros Briasoulis, Valentina Nardi, Rosalyn Adigun, Brooks S Edwards, Naveen L Pereira, Richard C Daly, Amir Lerman, Sudhir S Kushwaha
BACKGROUND: Cardiac allograft vasculopathy (CAV) is a major complication after heart transplantation (HT). Uric acid (UA) may play a role in CAV due to its role in stimulating T-cell-mediated immunity. Sirolimus is associated with CAV attenuation through a number of mechanisms, including immune-mediated effects. We aimed to determine whether UA is an independent predictor of CAV and whether conversion to sirolimus as primary immunosuppression modulates UA levels. METHODS: We retrospectively analyzed a cohort of 224 patients who underwent HT between 2004 and 2015 and had serial coronary intravascular ultrasound (IVUS) studies...
May 1, 2018: Journal of Heart and Lung Transplantation
https://www.readbyqxmd.com/read/29802081/donor-heart-selection-and-outcomes-an-analysis-of-over-2-000-cases
#2
Arezu Z Aliabadi-Zuckermann, Johannes Gökler, Alexandra Kaider, Julia Riebandt, Roxana Moayedifar, Emilio Osorio, Thomas Haberl, Phillipp Angleitner, Günther Laufer, John Forsythe, Ivan Knezevic, Bosko Skoric, Michiel Erasmus, Johan van Cleemput, Kadir Caliskan, Nicolaas De Jonge, Zoltan Szabolcs, Zsolt Prodán, Andrä Wasler, Christoph Bara, Mario Udovičić, Tim Sandhaus, Jens Garbade, Arjang Ruhparwar, Felix Schoenrath, Stephan Hirt, Herwig Antretter, Uwe Schulz, Manfred Richter, Josef Thul, Markus J Barten, Assad Haneya, Ivan Aleksic, Sandra Eifert, Michael Berchtold-Herz, Jacqueline Smits, Andreas O Zuckermann
BACKGROUND: Decision-making when offered a donor heart for transplantation is complex, and supportive data describing outcomes according to acceptance or non-acceptance choices are sparse. Our aim was to analyze donor heart acceptance decisions and associated outcomes at a single center, and after subsequent acceptance elsewhere. METHODS: This investigation was a retrospective analysis of data obtained from the University of Vienna Medical Center and Eurotransplant centers for the period 2001 to 2015...
April 30, 2018: Journal of Heart and Lung Transplantation
https://www.readbyqxmd.com/read/29802082/plasma-exchange-to-remove-heparin-induced-thrombocytopenia-antibodies-and-the-use-of-heparin-during-cardiopulmonary-bypass-in-critically-ill-cardiac-patients
#3
LETTER
Bhavadharini Ramu, Rebecca J Cogswell, Mark T Reding, Ranjit John, Cindy M Martin
No abstract text is available yet for this article.
April 27, 2018: Journal of Heart and Lung Transplantation
https://www.readbyqxmd.com/read/29709440/the-2018-ishlt-apm-ast-iccac-stsw-recommendations-for-the-psychosocial-evaluation-of-adult-cardiothoracic-transplant-candidates-and-candidates-for-long-term-mechanical-circulatory-support
#4
EDITORIAL
Mary Amanda Dew, Andrea F DiMartini, Fabienne Dobbels, Kathleen L Grady, Sheila G Jowsey-Gregoire, Annemarie Kaan, Kay Kendall, Quincy-Robyn Young, Susan E Abbey, Zeeshan Butt, Catherine C Crone, Sabina De Geest, Christina T Doligalski, Christiane Kugler, Laurie McDonald, Linda Ohler, Liz Painter, Michael G Petty, Desiree Robson, Thomas Schlöglhofer, Terry D Schneekloth, Jonathan P Singer, Patrick J Smith, Heike Spaderna, Jeffrey J Teuteberg, Roger D Yusen, Paula C Zimbrean
The psychosocial evaluation is well-recognized as an important component of the multifaceted assessment process to determine candidacy for heart transplantation, lung transplantation, and long-term mechanical circulatory support (MCS). However, there is no consensus-based set of recommendations for either the full range of psychosocial domains to be assessed during the evaluation, or the set of processes and procedures to be used to conduct the evaluation, report its findings, and monitor patients' receipt of and response to interventions for any problems identified...
April 27, 2018: Journal of Heart and Lung Transplantation
https://www.readbyqxmd.com/read/29907500/inhibition-of-regulated-necrosis-attenuates-receptor-interacting-protein-kinase-1-mediated-ischemia-reperfusion-injury-after-lung-transplantation
#5
Takashi Kanou, Akihiro Ohsumi, Hyunhee Kim, Manyin Chen, Xiaohui Bai, Zehong Guan, David Hwang, Marcelo Cypel, Shaf Keshavjee, Mingyao Liu
BACKGROUND: Increasing evidence indicates that regulated necrosis plays a critical role during cell death caused by ischemia-reperfusion (IR) injury. Necroptosis is one form of regulated necrosis. Necrostatin-1 (Nec-1), an inhibitor of receptor-interacting protein kinase 1 (RIPK1), is known to reduce necroptosis. We investigated the effect of Nec-1 treatment on IR-induced lung injury in a rat lung transplant model. METHODS: Lewis rats were divided into 4 groups (n = 6 each): (1) Control (no treatment), (2) Donor treatment (D), (3) Recipient treatment (R), and (4) Donor plus Recipient treatment (D+R) groups...
April 26, 2018: Journal of Heart and Lung Transplantation
https://www.readbyqxmd.com/read/29907499/incidence-of-temporary-mechanical-circulatory-support-before-heart-transplantation-and-impact-on-post-transplant-outcomes
#6
David Ouyang, Gunsagar Gulati, Richard Ha, Dipanjan Banerjee
BACKGROUND: Proposed changes to the United Network for Organ Sharing heart transplant allocation protocol will prioritize patients receiving temporary mechanical circulatory support (tMCS), including extracorporeal membrane oxygenation (ECMO), percutaneous ventricular assist devices (PVADs), and intra-aortic balloon pumps (IABPs). We sought to evaluate contemporary trends in the incidence and outcomes of patients who required tMCS during the hospitalization before heart transplantation...
April 26, 2018: Journal of Heart and Lung Transplantation
https://www.readbyqxmd.com/read/29802083/interagency-registry-for-mechanically-assisted-circulatory-support-report-on-the-total-artificial-heart
#7
Francisco A Arabía, Ryan S Cantor, Devin A Koehl, Vigneshwar Kasirajan, Igor Gregoric, Jaime D Moriguchi, Fardad Esmailian, Danny Ramzy, Joshua S Chung, Lawrence S Czer, Jon A Kobashigawa, Richard G Smith, James K Kirklin
BACKGROUND: We sought to better understand the patient population who receive a temporary total artificial heart (TAH) as bridge to transplant or as bridge to decision by evaluating data from the Interagency Registry for Mechanically Assisted Circulatory Support (INTERMACS) database. METHODS: We examined data related to survival, adverse events, and competing outcomes from patients who received TAHs between June 2006 and April 2017 and used hazard function analysis to explore risk factors for mortality...
April 26, 2018: Journal of Heart and Lung Transplantation
https://www.readbyqxmd.com/read/29907501/danazol-treatment-of-gastrointestinal-bleeding-in-left-ventricular-assist-device-supported-patients
#8
LETTER
Sarah Schettle, Badr Al Bawardy, Rabea Asleh, Saadia Sherazi, Elizabeth Rajan, John Stulak, Naveen Pereira
No abstract text is available yet for this article.
April 25, 2018: Journal of Heart and Lung Transplantation
https://www.readbyqxmd.com/read/29802084/usefulness-of-thrombosis-and-inflammation-biomarkers-in-chronic-thromboembolic-pulmonary-hypertension-sampling-plasma-and-surgical-specimens
#9
Nika Skoro-Sajer, Christian Gerges, Mario Gerges, Adelheid Panzenböck, Johannes Jakowitsch, Annabella Kurz, Shahrokh Taghavi, Roela Sadushi-Kolici, Ioana Campean, Walter Klepetko, David S Celermajer, Irene Marthe Lang
BACKGROUND: Chronic thromboembolic pulmonary hypertension (CTEPH) results from persistent pulmonary vascular obstructions, presumably due to inflammatory thrombosis. Because estimates of thrombus volume at diagnosis have no predictive value, we investigated the role of the thrombosis marker, D-dimer, and the inflammation marker, C-reactive protein (CRP), for predicting outcomes in CTEPH. METHODS: A total 289 consecutive patients with CTEPH were followed for 57 (median 45 to 69) months...
April 25, 2018: Journal of Heart and Lung Transplantation
https://www.readbyqxmd.com/read/29776811/first-in-man-use-of-the-mvad-axial-flow-pump-long-term-outcome
#10
LETTER
Marian Urban, Anfrew Woods, Nicola Robinson-Smith, Guy MacGowan, Chandrika Roysam, Stephan Schueler
No abstract text is available yet for this article.
April 25, 2018: Journal of Heart and Lung Transplantation
https://www.readbyqxmd.com/read/29752076/predictions-are-difficult-especially-about-the-future
#11
EDITORIAL
Michelle M Kittleson
No abstract text is available yet for this article.
April 25, 2018: Journal of Heart and Lung Transplantation
https://www.readbyqxmd.com/read/29754763/importance-and-clinical-implications-of-new-methods-for-grading-aortic-valve-regurgitation-in-patients-supported-with-a-continuous-flow-left-ventricular-assist-devices
#12
LETTER
Angelo M Dell'Aquila, Henryk Welp
No abstract text is available yet for this article.
April 24, 2018: Journal of Heart and Lung Transplantation
https://www.readbyqxmd.com/read/29754764/monitoring-of-early-humoral-immunity-to-identify-lung-recipients-at-risk-for-development-of-serious-infections-a-multicenter-prospective-study
#13
Elizabeth Sarmiento, Jose Cifrian, Leticia Calahorra, Carles Bravo, Sonia Lopez, Rosalia Laporta, Piedad Ussetti, Amparo Sole, Carmen Morales, Alicia de Pablos, Maria Jaramillo, Ikram Ezzahouri, Sandra García, Joaquin Navarro, Marcos Lopez-Hoyos, Javier Carbone
BACKGROUND: Infection is still a leading cause of death during the first year after lung transplantation. We performed a multicenter study among teaching hospitals to assess monitoring of early humoral immunity as a means of identifying lung recipients at risk of serious infections. METHODS: We prospectively analyzed 82 adult lung recipients at 5 centers in Spain. Data were collected before transplantation and at 7 and 30 days after transplantation. Biomarkers included IgG, IgM, IgA, complement factors C3 and C4, titers of antibodies to pneumococcal polysaccharide antigens (IgG, IgA, IgM) and antibodies to cytomegalovirus (IgG), and serum B-cell activating factor (BAFF) levels...
April 6, 2018: Journal of Heart and Lung Transplantation
https://www.readbyqxmd.com/read/29706574/early-detection-of-cardiac-allograft-vasculopathy-using-highly-automated-3-dimensional-optical-coherence-tomography-analysis
#14
Michal Pazdernik, Zhi Chen, Helena Bedanova, Josef Kautzner, Vojtech Melenovsky, Vladimir Karmazin, Ivan Malek, Ales Tomasek, Eva Ozabalova, Jan Krejci, Janka Franekova, Andreas Wahle, Honghai Zhang, Tomas Kovarnik, Milan Sonka
BACKGROUND: Optical coherence tomography (OCT)-based studies of cardiac allograft vasculopathy (CAV) published thus far have focused mainly on frame-based qualitative analysis of the vascular wall. Full capabilities of this inherently 3-dimensional (3D) imaging modality to quantify CAV have not been fully exploited. METHODS: Coronary OCT imaging was performed at 1 month and 12 months after heart transplant (HTx) during routine surveillance cardiac catheterization...
April 6, 2018: Journal of Heart and Lung Transplantation
https://www.readbyqxmd.com/read/29776812/preservation-with-%C3%AE-1-antitrypsin-improves-primary-graft-function-of-murine-lung-transplants
#15
Jessica Götzfried, Natalia F Smirnova, Carmela Morrone, Brice Korkmaz, Ali Önder Yildirim, Oliver Eickelberg, Dieter E Jenne
BACKGROUND: Vascular damage and primary graft dysfunction increase with prolonged preservation times of transplanted donor lungs. Hence, storage and conservation of donated lungs in protein-free, dextran-containing electrolyte solutions, like Perfadex, is limited to about 6 hours. We hypothesized that transplanted lungs are protected against neutrophil-mediated proteolytic damage by adding α1 -anti-trypsin (AAT), a highly abundant human plasma proteinase inhibitor, to Perfadex. METHODS: A realistic clinically oriented murine model of lung transplantation was used to simulate the ischemia-reperfusion process...
March 30, 2018: Journal of Heart and Lung Transplantation
https://www.readbyqxmd.com/read/29731239/indwelling-central-venous-catheter-occlusion-during-chronic-epoprostenol-infusion
#16
LETTER
Grzegorz Kopeć, Marcin Waligóra, Jakub Stępniewski, Piotr Podolec
No abstract text is available yet for this article.
March 30, 2018: Journal of Heart and Lung Transplantation
https://www.readbyqxmd.com/read/29731238/human-heart-transplantation-from-donation-after-circulatory-determined-death-donors-using-normothermic-regional-perfusion-and-cold-storage
#17
Simon Messer, Aravinda Page, Simon Colah, Richard Axell, Barbora Parizkova, Steven Tsui, Stephen Large
Heart transplantation from donation after circulatory-determined-death (DCD) donors is emerging as an additional avenue to increase heart transplant activity. Previous methods of DCD heart retrieval include direct procurement and cold storage, direct procurement, and machine perfusion and normothermic regional perfusion, followed by machine perfusion during transportation. Herein we report a further technique resulting in successful DCD heart transplantation utilizing normothermic regional perfusion and permitting functional assessment followed by cold storage...
March 30, 2018: Journal of Heart and Lung Transplantation
https://www.readbyqxmd.com/read/29703578/early-in-vivo-experience-with-the-pediatric-continuous-flow-total-artificial-heart
#18
Jamshid H Karimov, David J Horvath, Nicole Byram, Gengo Sunagawa, Barry D Kuban, Shengqiang Gao, Raymond Dessoffy, Kiyotaka Fukamachi
BACKGROUND: Heart transplantation in infants and children is an accepted therapy for end-stage heart failure, but donor organ availability is low and always uncertain. Mechanical circulatory support is another standard option, but there is a lack of intracorporeal devices due to size and functional range. The purpose of this study was to evaluate the in vivo performance of our initial prototype of a pediatric continuous-flow total artificial heart (P-CFTAH), comprising a dual pump with one motor and one rotating assembly, supported by a hydrodynamic bearing...
March 30, 2018: Journal of Heart and Lung Transplantation
https://www.readbyqxmd.com/read/29699851/blockade-of-adhesion-molecule-lymphocyte-function-associated-antigen-1-improves-long-term-heart-allograft-survival-in-mixed-chimeras
#19
Nina Pilat, Philipp Sabler, Christoph Klaus, Benedikt Mahr, Lukas Unger, Karin Hock, Mario Wiletel, Christoph Schwarz, Ivan Kristo, Heinz Regele, Thomas Wekerle
BACKGROUND: The mixed chimerism approach for intentional induction of donor-specific tolerance was shown to be successful in various models from mice to humans. For transplant patients, the approach would obviate the need for long-term immunosuppression and associated side effects; moreover, it would preclude the risk of late graft loss due to chronic rejection. Widespread clinical application is hindered by toxicities related to recipient pre-conditioning. Herein we aimed to investigate a clinically relevant protocol for tolerance induction to cardiac allografts, sparing CD40 blockade or T-cell depletion...
March 30, 2018: Journal of Heart and Lung Transplantation
https://www.readbyqxmd.com/read/29793656/a-case-of-recipient-derived-pulmonary-kaposi-sarcoma-after-bilateral-lung-transplantation
#20
LETTER
Julie Ng, Allison Cleary, Hisashi Tsukada, Hilary Goldberg
No abstract text is available yet for this article.
June 2018: Journal of Heart and Lung Transplantation
journal
journal
20152
1
2
Fetch more papers »
Fetching more papers... Fetching...
Read by QxMD. Sign in or create an account to discover new knowledge that matter to you.
Remove bar
Read by QxMD icon Read
×

Search Tips

Use Boolean operators: AND/OR

diabetic AND foot
diabetes OR diabetic

Exclude a word using the 'minus' sign

Virchow -triad

Use Parentheses

water AND (cup OR glass)

Add an asterisk (*) at end of a word to include word stems

Neuro* will search for Neurology, Neuroscientist, Neurological, and so on

Use quotes to search for an exact phrase

"primary prevention of cancer"
(heart or cardiac or cardio*) AND arrest -"American Heart Association"