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Journal of Heart and Lung Transplantation

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https://www.readbyqxmd.com/read/28527532/poor-outcomes-in-adolescent-lung-transplant-patients-why-the-gap
#1
EDITORIAL
Debra Boyer
No abstract text is available yet for this article.
May 4, 2017: Journal of Heart and Lung Transplantation
https://www.readbyqxmd.com/read/28457699/erratum
#2
(no author information available yet)
No abstract text is available yet for this article.
April 27, 2017: Journal of Heart and Lung Transplantation
https://www.readbyqxmd.com/read/28457698/cajita-ma-denhaerynck-k-dobbels-f-berben-l-russell-cl-davidson-pm-health-literacy-in-heart-transplantation-prevalence-correlates-and-associations-with-health-behaviors-findings-from-the-international-bright-study-j-heart-lung-transplant-2017-36-3-272-79
#3
https://www.readbyqxmd.com/read/28483300/donor-derived-ureaplasma-is-a-potentially-lethal-infection-in-lung-allograft-recipients
#4
LETTER
Ankit Bharat, G R Scott Budinger, Michael G Ison
No abstract text is available yet for this article.
April 24, 2017: Journal of Heart and Lung Transplantation
https://www.readbyqxmd.com/read/28506394/iron-its-complicated
#5
EDITORIAL
Ashish S Shah
No abstract text is available yet for this article.
April 19, 2017: Journal of Heart and Lung Transplantation
https://www.readbyqxmd.com/read/28495445/preservation-of-von-willebrand-factor-multimers-and-function-in-patients-with-an-evaheart-centrifugal-type-continuous-flow-left-ventricular-assist-device
#6
LETTER
Yuki Ichihara, Tomohiro Nishinaka, Masahide Komagamine, Yukiko Yamada, Kenji Yamazaki
No abstract text is available yet for this article.
April 19, 2017: Journal of Heart and Lung Transplantation
https://www.readbyqxmd.com/read/28487045/pentraxin-3-levels-in-bronchoalveolar-lavage-fluid-of-lung-transplant-recipients-with-invasive-aspergillosis
#7
Dima Kabbani, Archana Bhaskaran, Lianne G Singer, Alyajahan Bhimji, Coleman Rotstein, Shaf Keshavjee, W Conrad Liles, Shahid Husain
BACKGROUND: Invasive aspergillosis is the most common invasive fungal infection in lung transplant recipients. The use of galactomannan testing in bronchoalveolar lavage (BAL) fluid has improved diagnosis of invasive aspergillosis; however, false-positive results can lead to overdiagnosis and unnecessary treatment. The use of proinflammatory markers such as pentraxin 3 (PTX3) may help differentiate between Aspergillus colonization and disease. METHODS: BAL PTX3 concentrations were measured by enzyme-linked immunosorbent assay in 151 lung transplant recipients and 9 healthy control subjects...
April 19, 2017: Journal of Heart and Lung Transplantation
https://www.readbyqxmd.com/read/28479033/intragastric-balloon-for-management-of-morbid-obesity-in-a-candidate-for-heart-transplantation
#8
LETTER
Andrew C Storm, Neal K Lakdawala, Christopher C Thompson
No abstract text is available yet for this article.
April 19, 2017: Journal of Heart and Lung Transplantation
https://www.readbyqxmd.com/read/28457697/extended-distance-cardiac-allograft-can-successfully-be-utilized-without-impacting-long-term-survival
#9
Ann C Gaffey, Carol W Chen, Jennifer J Chung, Jason Han, Anjali Owens, Michael A Acker, Pavan Atluri
BACKGROUND: Despite the severe shortage of donor cardiac allografts, the general belief in worse outcomes with donors from prolonged distances has resulted in many centers greatly limiting the acceptable geographic distance of acceptable donors. However, with improvements in allograft preservation, it is likely that distance may be extended without compromising graft integrity. We hypothesized that recipients of appropriately selected allografts from greater distances would have equivalent long-term survival compared with recipients from closer geographic regions...
April 15, 2017: Journal of Heart and Lung Transplantation
https://www.readbyqxmd.com/read/28431982/red-blood-cells-and-left-ventricular-assist-devices-a-lifespan-under-stress
#10
EDITORIAL
Christopher S Hayward
No abstract text is available yet for this article.
March 29, 2017: Journal of Heart and Lung Transplantation
https://www.readbyqxmd.com/read/28465118/development-and-validation-of-a-major-adverse-transplant-event-mate-score-to-predict-late-graft-loss-in-pediatric-heart-transplantation
#11
Christopher S Almond, Helena Hoen, Joseph W Rossano, Chesney Castleberry, Scott R Auerbach, Lingyao Yang, Ashwin K Lal, Melanie D Everitt, Matthew Fenton, Seth A Hollander, Elfriede Pahl, Elizabeth Pruitt, David N Rosenthal, Doff B McElhinney, Kevin P Daly, Manisha Desai
BACKGROUND: There is inadequate power to perform a valid clinical trial in pediatric heart transplantation (HT) using a conventional end-point, because the disease is rare and hard end-points, such as death or graft loss, are infrequent. We sought to develop and validate a surrogate end-point involving the cumulative burden of post-transplant complications to predict death/graft loss to power a randomized clinical trial of maintenance immunosuppression in pediatric HT. METHODS: Pediatric Heart Transplant Study (PHTS) data were used to identify all children who underwent an isolated orthotopic HT between 2005 and 2014 who survived to 6 months post-HT...
March 24, 2017: Journal of Heart and Lung Transplantation
https://www.readbyqxmd.com/read/28431983/comparison-of-extracorporeal-photopheresis-and-alemtuzumab-for-the-treatment-of-chronic-lung-allograft-dysfunction
#12
Anna Moniodis, Keri Townsend, Alexander Rabin, Obadah Aloum, Jessica Stempel, Patrick Burkett, Phillip Camp, Miguel Divo, Souheil El-Chemaly, Hari Mallidi, Ivan Rosas, Anne Fuhlbrigge, Sophia Koo, Hilary J Goldberg
BACKGROUND: Survival after lung transplantation is limited by chronic lung allograft dysfunction (CLAD). Immunomodulatory therapies such as extracorporeal photopheresis (ECP) and alemtuzumab (AL) have been described for refractory CLAD, but comparative outcomes are not well defined. METHODS: We retrospectively reviewed spirometric values and clinical outcomes after therapy with ECP, AL, or no treatment (NT) in patients with CLAD who underwent transplant between January 2005 and December 2014...
March 24, 2017: Journal of Heart and Lung Transplantation
https://www.readbyqxmd.com/read/28431981/ventricular-assist-device-elicits-serum-natural-igg-that-correlates-with-the-development-of-primary-graft-dysfunction-following-heart-transplantation
#13
Sarah B See, Kevin J Clerkin, Peter J Kennel, Feifan Zhang, Matthew P Weber, Kortney J Rogers, Debanjana Chatterjee, Elena R Vasilescu, George Vlad, Yoshifumi Naka, Susan W Restaino, Maryjane A Farr, Veli K Topkara, Paolo C Colombo, Donna M Mancini, P Christian Schulze, Bruce Levin, Emmanuel Zorn
BACKGROUND: Pre-transplant sensitization is a limiting factor in solid-organ transplantation. In heart transplants, ventricular assist device (VAD) implantation has been associated with sensitization to human leukocyte antigens (HLA). The effect of VAD on non-HLA antibodies is unclear. We have previously shown that polyreactive natural antibodies (Nabs) contribute to pre-sensitization in kidney allograft recipients. Here we assessed generation of Nabs after VAD implantation in pre-transplant sera and examined their contribution to cardiac allograft outcome...
March 24, 2017: Journal of Heart and Lung Transplantation
https://www.readbyqxmd.com/read/28431980/shear-stress-alterations-in-the-celiac-trunk-of-patients-with-a-continuous-flow-left-ventricular-assist-device-as-shown-by-in-silico-and-in-vitro-flow-analyses
#14
Francesco Scardulla, Salvatore Pasta, Leonardo D'Acquisto, Sergio Sciacca, Valentina Agnese, Christian Vergara, Alfio Quarteroni, Francesco Clemenza, Diego Bellavia, Michele Pilato
BACKGROUND: The use of left ventricular assist devices (LVADs) to treat advanced cardiac heart failure is constantly increasing, although this device leads to high risk for gastrointestinal bleeding. METHODS: Using in-silico flow analysis, we quantified hemodynamic alterations due to continuous-flow LVAD (HeartWare, Inc., Framingham, MA) in the celiac trunk and major branches of the abdominal aorta, and then explored the relationship between wall shear stress (WSS) and celiac trunk orientation...
March 24, 2017: Journal of Heart and Lung Transplantation
https://www.readbyqxmd.com/read/28416103/a-new-twist-on-right-heart-failure-with-left-ventricular-assist-systems
#15
EDITORIAL
Brian A Houston, Keyur B Shah, Mandeep R Mehra, Ryan J Tedford
Despite significant efforts to predict and prevent right heart failure, it remains a leading cause of morbidity and mortality after implantation of left ventricular assist systems (LVAS). In this Perspective, we review the underappreciated anatomic and physiologic principles that govern the relationship between left and right heart function and contribute to this phenomenon. This includes the importance of considering the right ventricle (RV) and pulmonary arterial circuit as a coupled system; the contribution of the left ventricle (LV) to RV contractile function and the potential negative impact of acutely unloading the LV; the influence of the pericardium and ventricular twist on septal function; the role of RV deformation in reduced mechanical efficiency after device placement; and the potential of ongoing stressors of an elevated right-sided preload...
March 24, 2017: Journal of Heart and Lung Transplantation
https://www.readbyqxmd.com/read/28396089/the-new-united-states-heart-allocation-policy-progress-through-collaborative-revision
#16
EDITORIAL
Ryan R Davies, Maryjane Farr, Scott Silvestry, Liz Robbins Callahan, Leah Edwards, Dan M Meyer, Kimberly Uccellini, Kevin M Chan, Joseph G Rogers
No abstract text is available yet for this article.
March 21, 2017: Journal of Heart and Lung Transplantation
https://www.readbyqxmd.com/read/28389169/hard-to-swallow-dysmotility-reflux-and-chronic-lung-allograft-dysfunction-in-pediatric-lung-transplantation
#17
EDITORIAL
Joshua A Blatter
No abstract text is available yet for this article.
March 20, 2017: Journal of Heart and Lung Transplantation
https://www.readbyqxmd.com/read/28389168/how-do-you-mend-a-donor-heart
#18
EDITORIAL
Peter Macdonald
No abstract text is available yet for this article.
March 20, 2017: Journal of Heart and Lung Transplantation
https://www.readbyqxmd.com/read/28365176/into-the-hearts-of-babes-stem-cell-therapy-for-pediatric-heart-failure
#19
EDITORIAL
Jessica C Garbern, Kevin P Daly
No abstract text is available yet for this article.
March 9, 2017: Journal of Heart and Lung Transplantation
https://www.readbyqxmd.com/read/28365177/high-dose-vitamin-d-after-lung-transplantation-a-randomized-trial
#20
Robin Vos, David Ruttens, Stijn E Verleden, Elly Vandermeulen, Hannelore Bellon, Anke Van Herck, Annelore Sacreas, Tobias Heigl, Veronique Schaevers, Dirk E Van Raemdonck, Eric K Verbeken, Arne P Neyrinck, Lieven J Dupont, Jonas Yserbyt, Bart M Vanaudenaerde, Geert M Verleden
BACKGROUND: Vitamin D may have innate immunomodulatory functions with potentially beneficial therapeutic effects in lung transplant recipients. METHODS: This was a single-center, double blind, randomized, placebo-controlled, prevention trial of once-monthly oral vitamin D (cholecalciferol; 100,000 IU, n = 44) vs placebo (n = 43) during 2 years in adult lung transplant recipients enrolled from October 2010 to August 2013. Primary outcome was prevalence of chronic lung allograft dysfunction (CLAD) 3 years after transplantation...
March 8, 2017: Journal of Heart and Lung Transplantation
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